Teikyo University School of Medicine, Department of Dermatology, Associate Professor

1999.6 - 2001.6

Kitasato Institute Hospital, Senior Staff Dermatologist

1995.4 - 1999.5

Kitasato Institute Hospital, Staff Dermatologist

1994.6 - 1995.3

Department of Medicine, Division of Dermatology, University of Washington, School of Medicine, Senior research fellow

1994.4 - 1994.5

Department of Biological Structure, University of Washington, School of Medicine, Senior research fellow

1992.7 - 1994.3

Shimizu City Hospital, Senior Staff Dermatologist

1992.5 - 1992.6

Shimizu City Hospital, Staff Dermatologist

1990.7 - 1992.4

Two novel anti-aminoacyl tRNA synthetase antibodies: Autoantibodies against cysteinyl-tRNA synthetase and valyl-tRNA synthetase.

Muro Y, Yamashita Y, Koizumi H, Ogawa-Momohara M, Takeichi T, Mitsuma T, Akiyama M

Autoimmunity reviews   Vol. 21 ( 12 ) page： 103204   2022.10

Long-term risk of cancer development among anti-Th/To antibody-positive systemic sclerosis patients: comment on the article by Mecoli et al.

Yamashita Y, Muro Y, Koizumi H, Takeichi T, Yamano Y, Kondoh Y, Akiyama M

Arthritis & rheumatology (Hoboken, N.J.)     2021.8

Immune recognition of lysyl-tRNA synthetase and isoleucyl-tRNA synthetase by anti-OJ antibody-positive sera.

Muro Y, Yamano Y, Yoshida K, Oto Y, Nakajima K, Mitsuma T, Kikuchi S, Matsumae A, Ogawa-Momohara M, Takeichi T, Kondoh Y, Katayama M, Todoroki Y, Tanaka Y, Satoh M, Akiyama M

Journal of autoimmunity   Vol. 122   page： 102680   2021.8

Altered replication stress response due to CARD14 mutations promotes recombination-induced revertant mosaicism.

Miyauchi T, Suzuki S, Takeda M, Peh JT, Aiba M, Natsuga K, Fujita Y, Takeichi T, Sakamoto T, Akiyama M, Shimizu H, Nomura T

American journal of human genetics   Vol. 108 ( 6 ) page： 1026 - 1039   2021.6

Autoantibody profiles in patients' sera associated with distribution patterns of dermatomyositis skin symptoms.

Ogawa-Momohara M, Kinoshita F, Muro Y, Kobayashi Y, Takeichi T, Akiyama M

Journal of the American Academy of Dermatology   Vol. 84 ( 6 ) page： 1720 - 1722   2021.6

Extensive multiple organ involvement in VEXAS syndrome.

Takahashi N, Takeichi T, Nishida T, Takahashi Y, Sato J, Yamamura M, Ogi T, Akiyama M

Arthritis & rheumatology (Hoboken, N.J.)     2021.4

Hair graying with aging in mice carrying oncogenic RET.

Aging cell   Vol. 19 ( 11 ) page： e13273   2020.11

Association of Topical Minoxidil With Autosomal Recessive Woolly Hair/Hypotrichosis Caused by LIPH Pathogenic Variants

Taki Tomoki, Tanahashi Kana, Takeichi Takuya, Yoshikawa Takenori, Murase Yuya, Sugiura Kazumitsu, Akiyama Masashi

JAMA DERMATOLOGY   Vol. 156 ( 10 ) page： 1030 - 1032   2020.10

<i>Staphylococcus</i> Agr virulence is critical for epidermal colonization and associates with atopic dermatitis development.

Science translational medicine   Vol. 12 ( 551 )   2020.7

Frequent FOXA1-Activating Mutations in Extramammary Paget's Disease

Takeichi Takuya, Okuno Yusuke, Matsumoto Takaaki, Tsunoda Nobuyuki, Suzuki Kyogo, Tanahashi Kana, Kono Michihiro, Kikumori Toyone, Muro Yoshinao, Akiyama Masashi

CANCERS   Vol. 12 ( 4 )   2020.4

SDR9C7 catalyzes critical dehydrogenation of acylceramides for skin barrier formation.

Takeichi T, Hirabayashi T, Miyasaka Y, Kawamoto A, Okuno Y, Taguchi S, Tanahashi K, Murase C, Takama H, Tanaka K, Boeglin WE, Calcutt MW, Watanabe D, Kono M, Muro Y, Ishikawa J, Ohno T, Brash AR, Akiyama M

The Journal of clinical investigation   Vol. 130 ( 2 ) page： 890 - 903   2020.2

A novel NCSTN missense mutation in the signal peptide domain causes hidradenitis suppurativa, which has features characteristic of an autoinflammatory keratinization disease

Takeichi T., Matsumoto T., Nomura T., Takeda M., Niwa H., Kono M., Shimizu H., Ogi T., Akiyama M.

BRITISH JOURNAL OF DERMATOLOGY   Vol. 182 ( 2 ) page： 491 - 493   2020.2

CASE REPORT: ADVANCED MELANOMA PATIENT WITH FAVORABLE RESPONSE TO IMMUNE CHECKPOINT INHIBITOR TREATMENT SHOWS SEVERE ERYTHEMA CIRCINATUM WITH ANTI-SS-A ANTIBODIES

Ogawa-Momohara Mariko, Muro Yoshinao, Goto Katsunobu, Obuse Chikashi, Satoh Minoru, Kono Michihiro, Akiyama Masashi

ANNALS OF THE RHEUMATIC DISEASES   Vol. 78   page： 1481 - 1482   2019.6

CLINICAL CHARACTERISTICS OF ANTI-RO52A AND ANTI-RO52B ANTIBODIES IN DERMATOMYOSITIS/POLYMYOSITIS

Ogawa-Momohara Mariko, Muro Yoshinao, Akiyama Masashi

ANNALS OF THE RHEUMATIC DISEASES   Vol. 78   page： 851 - 852   2019.6

More than keratitis, ichthyosis, and deafness: multisystem effects of lethal GJB2 mutations.

Lilly E, Bunick CG, Maley AM, Zhang S, Spraker MK, Theos AJ, Vivar KL, Seminario-Vidal L, Bennett AE, Sidbury R, Ogawa Y, Akiyama M, Binder B, Hadj-Rabia S, Morotti RA, Glusac EJ, Choate KA, Richard G, Milstone LM

Journal of the American Academy of Dermatology   Vol. 80 ( 3 ) page： 617 - 625   2019.3

Early-onset generalized pustular psoriasis is representative of autoinflammatory keratinization diseases.

Akiyama M

The Journal of allergy and clinical immunology     2018.12

Reduction of stratum corneum ceramides in Neu-Laxova syndrome caused by phosphoglycerate dehydrogenase deficiency

Takeichi Takuya, Okuno Yusuke, Kawamoto Akane, Inoue Takeshi, Nagamoto Eiko, Murase Chiaki, Shimizu Eri, Tanaka Kenichi, Kageshita Yuichi, Fukushima Satoshi, Kono Michihiro, Ishikawa Junko, Ihn Hironobu, Takahashi Yoshiyuki, Akiyama Masashi

JOURNAL OF LIPID RESEARCH   Vol. 59 ( 12 ) page： 2413-2420   2018.12

Sterol profiles are valuable biomarkers for phenotype expression of Conradi-Hunermann-Happle syndrome with EBP mutations

Takeichi T., Honda A., Okuno Y., Kojima D., Kono M., Nakamura Y., Tohyama M., Tanaka T., Aoyama Y., Akiyama M.

BRITISH JOURNAL OF DERMATOLOGY   Vol. 179 ( 5 ) page： 1186-1188   2018.11

Bilateral striatal necrosis and dyschromatosis symmetrica hereditaria: A-I editing efficiency of ADAR1 mutants and phenotype expression

Kono M., Suganuma M., Dutta A., Ghosh S. K., Takeichi T., Muro Y., Akiyama M.

BRITISH JOURNAL OF DERMATOLOGY   Vol. 179 ( 2 ) page： 509-511   2018.8

Two cases of generalized pustular psoriasis complicated by IgG4-related disease

Miyazawa H., Fujita Y., Iwata H., Ishikawa Y., Nishio S., Ishijima K., Shinmei Y., Takeichi T., Goto K., Oi R., Akiyama M., Shimizu H.

BRITISH JOURNAL OF DERMATOLOGY   Vol. 179 ( 2 ) page： 537-539   2018.8

Hand, Foot, and Mouth Disease in an Adult

Murase Chiaki, Akiyama Masashi

NEW ENGLAND JOURNAL OF MEDICINE   Vol. 378 ( 14 ) page： E20-E20   2018.4

Chromosomal inversions as a hidden disease-modifying factor for somatic recombination phenotypes

Nomura Toshifumi, Suzuki Shotaro, Miyauchi Toshinari, Takeda Masae, Shinkuma Satoru, Fujita Yasuyuki, Nishie Wataru, Akiyama Masashi, Shimizu Hiroshi

JCI INSIGHT   Vol. 3 ( 6 )   2018.3

Autoinflammatory keratinization diseases

Akiyama Masashi, Takeichi Takuya, McGrath John A., Sugiura Kazumitsu

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY   Vol. 140 ( 6 ) page： 1545 - 1547   2017.12

Biallelic Mutations in KDSR Disrupt Ceramide Synthesis and Result in a Spectrum of Keratinization Disorders Associated with Thrombocytopenia

Takeichi Takuya, Torrelo Antonio, Lee John Y. W., Ohno Yusuke, Luisa Lozano Maria, Kihara Akio, Liu Lu, Yasuda Yuka, Ishikawa Junko, Murase Takatoshi, Belen Rodrigo Ana, Fernandez-Crehuet Pablo, Toi Yoichiro, Mellerio Jemima, Rivera Jose, Vicente Vicente, Kelsell David P., Nishimura Yutaka, Okuno Yusuke, Kojima Daiei, Ogawa Yasushi, Sugiura Kazumitsu, Simpson Michael A., McLean W. H. Irwin, Akiyama Masashi, McGrath John A.

JOURNAL OF INVESTIGATIVE DERMATOLOGY   Vol. 137 ( 11 ) page： 2344-2353   2017.11

Autosomal dominant familial generalized pustular psoriasis caused by a CARD14 mutation

Takeichi T., Kobayashi A., Ogawa E., Okuno Y., Kataoka S., Kono M., Sugiura K., Okuyama R., Akiyama M.

BRITISH JOURNAL OF DERMATOLOGY   Vol. 177 ( 4 ) page： E133-E135   2017.10

Chromosomal inversions as a hidden disease-modifying factor

Nomura T., Suzuki S., Miyauchi T., Takeda M., Fujita Y., Nishie W., Akiyama M., Shimizu H.

JOURNAL OF INVESTIGATIVE DERMATOLOGY   Vol. 137 ( 10 ) page： S226-S226   2017.10

A Child with Epidermolytic Ichthyosis from a Parent with Epidermolytic Nevus: Risk Evaluation of Transmission from Mosaic to Germline

Kono Michihiro, Suga Yasushi, Akashi Tomohiro, Ito Yasutomo, Takeichi Takuya, Muro Yoshinao, Akiyama Masashi

JOURNAL OF INVESTIGATIVE DERMATOLOGY   Vol. 137 ( 9 ) page： 2024 - 2026   2017.9

Mutational analysis of 29 patients with autosomal-recessive woolly hair and hypotrichosis: LIPH mutations are extremely predominant in autosomal-recessive woolly hair and hypotrichosis in Japan

Takeichi T., Tanahashi K., Taki T., Kono M., Sugiura K., Akiyama M.

BRITISH JOURNAL OF DERMATOLOGY   Vol. 177 ( 1 ) page： 290-292   2017.7

Toll-like receptor 4 antagonist TAK-242 inhibits autoinflammatory symptoms in DITRA Reviewed

Shibata A, Sugiura K, Furuta Y, Mukumoto Y, Kaminuma O, Akiyama M

J Autoimmun   Vol. 80   page： 28 - 38   2017.6

PNPLA1 has a crucial role in skin barrier function by directing acylceramide biosynthesis. Reviewed

Hirabayashi T, Anjo T, Kaneko A, Senoo Y, Shibata A, Takama H, Yokoyama K, Nishito Y, Ono T, Taya C, Muramatsu K, Fukami K, Muñoz-Garcia A, Brash A, Ikeda K, Arita M, Akiyama M, Murakami M.

Nat Commun   Vol. 8   page： 14609   2017.3

Large Intragenic Deletion in DSTYK Underlies Autosomal-Recessive Complicated Spastic Paraparesis, SPG23.

Lee JYW, Hsu CK, Michael M, Nanda A, Liu L, McMillan JR, Pourreyron C, Takeichi T, Tolar J, Reid E, Hayday T, Blumen SC, Abu-Mouch S, Straussberg R, Basel-Vanagaite L, Barhum Y, Zouabi Y, Al-Ajmi H, Huang HY, Lin TC, Akiyama M, Lee JYY, McLean WHI, Simpson MA, Parsons M, McGrath JA

American journal of human genetics   Vol. 100 ( 2 ) page： 364 - 370   2017.2

Pityriasis Rubra Pilaris Type V as an Autoinflammatory Disease by CARD14 Mutations

Takeichi Takuya, Sugiura Kazumitsu, Nomura Toshifumi, Sakamoto Taiko, Ogawa Yasushi, Oiso Naoki, Futei Yuko, Fujisaki Aki, Koizumi Akiko, Aoyama Yumi, Nakajima Kimiko, Hatano Yutaka, Hayashi Kei, Ishida-Yamamoto Akemi, Fujiwara Sakuhei, Sano Shigetoshi, Iwatsuki Keiji, Kawada Akira, Suga Yasushi, Shimizu Hiroshi, McGrath John A., Akiyama Masashi

JAMA DERMATOLOGY   Vol. 153 ( 1 ) page： 66-70   2017.1

Germline NLRP1 mutations cause skin inflammatory and cancer susceptibility syndromes via inflammasome activation Reviewed

  Vol. 167 ( 1 ) page： 187-202   2016.9

Essential role of the cytochrome P450 CYP4F22 in the production of acylceramide, the key lipid for skin permeability barrier formation. Reviewed

Ohno Y, Nakamichi S, Ohkuni A, Kamiyama N, Naoe A, Tsujimura H, Yokose U, Sugiura K, Ishikawa J, Akiyama M, Kihara A

Proc Natl Acad Sci USA   Vol. 112 ( 25 ) page： 7707-7712   2015.6

Autoantibodies to DNA mismatch repair enzymes in polymyositis/dermatomyositis and other autoimmune conditions: a possible marker of favorable prognosis Reviewed

Muro Y, Nakashima R, Hosono Y, Sugiura K, Mimori T, Akiyama M

Arthritis Rheumatol   Vol. 66 ( 12 ) page： 3457-3462   2014.12

Epithelial inflammation resulting from an inherited loss-of-function mutation in EGFR. Reviewed

Campbell P, Morton PE, Takeichi T, Salam A, Roberts N, Proudfoot LE, Mellerio JE, Aminu K, Wellington C, Patil SN, Akiyama M, Liu L, McMillan JR, Aristodemou S, Ishida-Yamamoto A, Abdul-Wahab A, Petrof G, Fong K, Harnchoowong S, Stone KL, Harper JI, McLean WH, Simpson MA, Parsons M, McGrath JA

The Journal of investigative dermatology   Vol. 134 ( 10 ) page： 2570-8   2014.10

Solitary organizing pneumonia mimicking lung adenocarcinoma in systemic sclerosis. Reviewed

Sugiura K, Muro Y, Akiyama M

Arthritis & rheumatology (Hoboken, N.J.)   Vol. 66 ( 9 ) page： 2648   2014.9

Revertant mutation releases confined lethal mutation, opening Pandora's box: a novel genetic pathogenesis. Reviewed

Ogawa Y, Takeichi T, Kono M, Hamajima N, Yamamoto T, Sugiura K, Akiyama M.

PLoS Genet   Vol. 10 ( 5 ) page： e1004276   2014.5

Comprehensive screening for a complete set of Japanese-population-specific filaggrin gene mutations Reviewed

Kono M, Nomura T, Oguchi Y, Mizuno O, Suzuki S, Tsujiuchi H, Hamajima N, McLean WHI, Shimizu H, Akiyama M

Allergy   Vol. 69 ( 4 ) page： 537-540   2014.4

Mutations in the Grainyhead-like 2 transcription factor result in an autosomal recessive ectodermal dysplasia syndrome Reviewed

Petrof G, Nanda A, Howden J, Takeichi T, McMillan JR, Aristodemou S, Ozoemena L, Liu L, South AP, Pourreyron C, Dafou D, Proudfoot LE, Al-Ajmi H, Akiyama M, McLean WHI, Simpson MA, Parsons M, McGrath JA

Am J Hum Genet   Vol. 95 ( 3 ) page： 308-314   2014.3

High survival rate of harlequin ichthyosis in Japan. Reviewed

Shibata A, Ogawa Y, Sugiura K, Muro Y, Abe R, Suzuki T, Akiyama M

Journal of the American Academy of Dermatology   Vol. 70 ( 2 ) page： 387-8   2014.2

The majority of generalized pusular psoriasis without psoriasis vulgaris is caused by deficiency of interleukin-36 receptor antagonist Reviewed

Sugiura K, Takemoto A, Yamaguchi M, Takahashi H, Shoda Y, Mitsuma T, Tsuda K, Nishida E, Togawa Y, Nakajima K, Sakakibara A, Kawachi S, Shimizu M, Ito Y, Takeichi T, Kono M, Ogawa Y, Muro Y, Ishida-Yamamoto A, Sano S, Matsue H, Morita A, Mizutani H, Iizuka H, Muto M, Akiyama M

J Invest Dermatol   Vol. 133 ( 11 ) page： 2514-2521   2013.11

Whole-exome sequencing identifies ADAM10 mutations as a cause of reticulate acropigmentation of Kitamura, a clinical entity distinct from Dowling-Degos disease Reviewed

Kono M, Sugiura K, Suganuma M, Hayashi M, Takama H, Suzuki T, Matsunaga K, Tomita Y, Akiyama M

Hum Mol Genet   Vol. 22 ( 17 ) page： 3524-3533   2013.5

The β9 loop domain of PA-PLA1α has a crucial role in autosomal recessive woolly hair/hypotrichosis. Reviewed

  Vol. 132 ( 8 ) page： 2093-5   2012.8

Haploinsufficiency for AAGAB causes clinically heterogeneous forms of punctate palmoplantar keratoderma Reviewed

Pohler E, Mamai O, Hirst J, Zamiri M, Horn H, Nomura T, Irvine AD, Moran BE, Wilson NJ, Smith FJD, Goh CSM, Sandilands A, Cole C, Barton GJ, Evans AT, Shimizu H, Akiyama M, Suehiro A, Konohana I, Shboul M, Teissier, Boussofara L, Denguezli M, Saad A, Gribaa M, Dopping-Hepenstal PJ, McGrath JA, Brown SJ, Goudie DR, Reversade B, Munro CS, McLean WHI

Nature Genetics   Vol. 44   page： 1272-1276   2012

Revised nomenclature and classification of inherited ichthyoses: results of the First Ichthyosis Consensus Conference in Sorèze 2009. Reviewed

Oji V, Tadini G, Akiyama M, Blanchet Bardon C, Bodemer C, Bourrat E, Coudiere P, DiGiovanna JJ, Elias P, Fischer J, Fleckman P, Gina M, Harper J, Hashimoto T, Hausser I, Hennies HC, Hohl D, Hovnanian A, Ishida-Yamamoto A, Jacyk WK, Leachman S, Leigh I, Mazereeuw-Hautier J, Milstone L, Morice-Picard F, Paller AS, Richard G, Schmuth M, Shimizu H, Sprecher E, Van Steensel M, Taïeb A, Toro JR, Vabres P, Vahlquist A, Williams M, Traupe H

  Vol. 63 ( 4 ) page： 607-41   2010.10

Bone marrow transplantation restores epidermal basement membrane protein expression and rescues epidermolysis bullosa model mice Reviewed

Fujita Y, Abe R, Inokuma D, Sasaki M, Hoshina D, Natsuga K, Nishie W, McMillan JR, Nakamura H, Shimizu T, Akiyama M, Sawamura D, Shimizu H

Proc Natl Acad Sci U S A   Vol. 107 ( 32 ) page： 14345-50   2010.8

Harlequin ichthyosis model mouse reveals alveolar collapse and severe fetal skin barrier defects Reviewed

Yanagi T, Akiyama M, Nishihara H, Sakai K, Nishie W, Tanaka S, Shimizu H

Hum Mol Genet   Vol. 17 ( 19 ) page： 3075-83   2008.10

Oncostatin M receptor-beta mutations underlie familial primary localized cutaneous amyloidosis Reviewed

Arita K, South AP, Hans-Filho G, Sakuma TH, Lai-Cheong J, Clements S, Odashiro M, Odashiro DN, Hans-Neto G, Hans NR, Holder MV, Bhogal BS, Hartshorne ST, Akiyama M, Shimizu H, McGrath JA

Am J Hum Genet   Vol. 82 ( 1 ) page： 73-80   2008.1

Humanization of autoantigen Reviewed

Nishie W, Sawamura D, Goto M, Ito K, Shibaki A, McMillan JR, Sakai K, Nakamura H, Olasz E, Yancey KB, Akiyama M, Shimizu H

Nat Med   Vol. 13 ( 3 ) page： 378-83   2007.3

Unique mutations in the filaggrin gene in Japanese patients with ichthyosis vulgaris and atopic dermatitis Reviewed

Nomura T, Sandilands A, Akiyama M, Liao H, Evans AT, Sakai K, Ota M, Sugiura H, Yamamoto K, Sato H, Palmer CN, Smith FJ, McLean WH, Shimizu H

J Allergy Clin Immunol   Vol. 119 ( 2 ) page： 434-40   2007.2

Mutations in lipid transporter ABCA12 in harlequin ichthyosis and functional recovery by corrective gene transfer Reviewed

Akiyama M, Sugiyama-Nakagiri Y, Sakai K, McMillan JR, Goto M, Arita K, Tsuji-Abe Y, Tabata N, Matsuoka K, Sasaki R, Sawamura D, Shimizu H

J Clin Invest   Vol. 115 ( 7 ) page： 1777-84   2005.7

Loss of kindlin-1, a human homolog of the Caenorhabditis elegans actin-extracellular-matrix linker protein UNC-112, causes Kindler syndrome Reviewed

Siegel DH, Ashton GH, Penagos HG, Lee JV, Feiler HS, Wilhelmsen KC, South AP, Smith FJ, Prescott AR, Wessagowit V, Oyama N, Akiyama M, Al Aboud D, Al Aboud K, Al Githami A, Al Hawsawi K, Al Ismaily A, Al-Suwaid R, Atherton DJ, Caputo R, Fine JD, Frieden IJ, Fuchs E, Haber RM, Harada T, Kitajima Y, Mallory SB, Ogawa H, Sahin S, Shimizu H, Suga Y, Tadini G, Tsuchiya K, Wiebe CB, Wojnarowska F, Zaghloul AB, Hamada T, Mallipeddi R, Eady RA, McLean WH, McGrath JA, Epstein EH

Am J Hum Genet   Vol. 73 ( 1 ) page： 174-87   2003.7

Oesophageal involvement in pemphigus vulgaris Reviewed

Gomi H, Akiyama M, Yakabi K, Nakamura T, Matsuo I

Lancet   Vol. 354 ( 9192 ) page： 1794   1999.11

Prenatal diagnosis of tyrosinase-negative oculocutaneous albinism Reviewed

Shimizu H, Ishiko A, Kikuchi A, Akiyama M, Suzumori K, Nishikawa T

Lancet   Vol. 340 ( 8821 ) page： 739-40   1992.9

Dual clinical features of fine and rough scales seen in a combined ichthyosis vulgaris and X-linked recessive ichthyosis patient with atopic dermatitis.

Nakane Y, Yoshikawa T, Takeichi T, Kono M, Akiyama M

The Journal of dermatology     2023.9

Treatment of Severe Dermatitis, Multiple Allergies, and Metabolic Wasting With Dupilumab.

Koike Y, Takeichi T, Ishii N, Waseda T, Murayama N, Akiyama M, Murota H

JAMA dermatology   Vol. 159 ( 9 ) page： 1009 - 1011   2023.9

Mild generalised pustular psoriasis patient with a heterozygous hypomorphic MPO variant successfully treated with granulocyte and monocyte adsorption apheresis.

Takeichi T, Yoshikawa T, Iqbal MN, Farooq M, Taki T, Muro Y, Shimomura Y, Seishima M, Akiyama M

Experimental dermatology   Vol. 32 ( 9 ) page： 1557 - 1562   2023.9

Giant condyloma of Buschke-Löwenstein in a Netherton syndrome patient, successfully treated with cryotherapy and intravenous immunoglobulin.

Sawa M, Murase C, Yamada N, Fukaura R, Tetsuka N, Sato Y, Takeichi T, Akiyama M

The Journal of dermatology   Vol. 50 ( 9 ) page： e289 - e291   2023.9

English version of Japanese guidance for biologics in treating atopic dermatitis.

Saeki H, Akiyama M, Abe M, Igarashi A, Imafuku S, Ohya Y, Katoh N, Kameda H, Kabashima K, Tsunemi Y, Hide M, Ohtsuki M, Committee for reviewing the safety of atopic dermatitis/urticaria treatment, Japanese Dermatological Association

The Journal of dermatology     2023.8

Cathepsin and cutaneous disorders of cornification and inflammation: their close links.

Akiyama M

The British journal of dermatology   Vol. 189 ( 3 ) page： 256 - 257   2023.8

Methicillin-resistant Staphylococcus aureus-induced staphylococcal scalded skin syndrome in a preterm infant, and subsequent toxigenic analysis.

Fukaura R, Terashima-Murase C, Ota M, Noda H, Oka K, Ishihara Y, Shibayama K, Akiyama M

The Journal of dermatology     2023.8

Plucked scalp hair follicle samples are useful RNA sources for mRNA analysis of most genodermatosis-associated genes.

Takeuchi S, Takeichi T, Muro Y, Shimamura T, Akiyama M

Journal of dermatological science   Vol. 111 ( 2 ) page： 68 - 70   2023.8

Anti-KIF20B autoantibodies in systemic autoimmune rheumatic diseases: Their high prevalence in systemic lupus erythematosus.

Koizumi H, Muro Y, Yamashita Y, Takeichi T, Fritzler MJ, Akiyama M

The Journal of dermatology   Vol. 50 ( 8 ) page： 990 - 998   2023.8

Ichthyotic skin phenotype induced by the chronic activation of Toll-like receptor 2, and autoinflammation.

Takeichi T, Muro Y, Akiyama M

The British journal of dermatology   Vol. 189 ( 2 ) page： 252   2023.7

An in-frame 18 bp deletion in linker domain L1 of KRT9 identified in a Japanese patient with epidermolytic palmoplantar keratoderma.

Omi M, Takeichi T, Chiba T, Asano Y, Muro Y, Akiyama M

The Journal of dermatology     2023.7

Myiasis on a spindle cell squamous cell carcinoma: A scanning electron microscope observation of Lucilia sericata larvae.

Fukaura R, Terashima-Murase C, Mori S, Higa Y, Akiyama M

The Journal of dermatology   Vol. 50 ( 7 ) page： 964 - 966   2023.7

Cutaneous manifestations of microscopic polyangiitis successfully controlled with avacopan alone

Kamiya Satoshi, Koizumi Haruka, Suzuki Yuika, Imai Satoko, Yamashita Yuta, Ogawa-Momohara Mariko, Takeichi Takuya, Muro Yoshinao, Yasuda Kazushi, Akiyama Masashi

JOURNAL OF DERMATOLOGY   Vol. 50 ( 7 ) page： E206 - E207   2023.7

Recent Advances in Clinical Research on Rare Intractable Hereditary Skin Diseases in Japan.

Akiyama M, Takeichi T, Ikeda S, Ishiko A, Kurosawa M, Murota H, Shimomura Y, Suzuki T, Tamai K, Tanaka A, Terui T, Amagai M

The Keio journal of medicine     2023.6

Functional preservation benefits of minimal surgery for extramammary Paget's disease.

Okumura M, Ogata D, Namikawa K, Takahashi A, Akiyama M, Yamazaki N

Experimental dermatology     2023.6

Diagnosis of acute generalized pustular bacterid facilitated by point-of-care testing.

Fukaura R, Terashima-Murase C, Tanahashi K, Takeichi T, Akiyama M

The Journal of dermatology     2023.6

Adenosquamous carcinoma of the Bartholin gland treated with surgery and radiotherapy.

Okumura M, Ogata D, Namikawa K, Takahashi A, Nishimura Y, Mori T, Yoshida H, Akiyama M, Yamazaki N

European journal of dermatology : EJD   Vol. 33 ( 3 ) page： 309 - 311   2023.6

The use of certolizumab pegol to successfully treat generalized pustular psoriasis combined with psoriatic uveitis

Yatsuzuka Kazuki, Matsumoto Takuya, Sakane Yuri, Fukaura Ryo, Takeichi Takuya, Akiyama Masashi, Murakami Masamoto

JOURNAL OF DERMATOLOGY   Vol. 50 ( 6 ) page： E175 - E176   2023.6

Successful combination therapy of bimekizumab and granulocyte monocyte adsorption apheresis for generalized pustular psoriasis complicated with microscopic polyangiitis

Shukuin Rie, Koizumi Haruka, Ebata Aoi, Imai Satoko, Yamashita Yuta, Ogawa-Momohara Mariko, Takeichi Takuya, Muro Yoshinao, Takami Norito, Akiyama Masashi

JOURNAL OF DERMATOLOGY   Vol. 50 ( 6 ) page： E181 - E182   2023.6

COVID-19 infection- and vaccination-related exacerbation of Darier's disease in a single patient

Fukaura Ryo, Takeichi Takuya, Ebata Aoi, Muro Yoshinao, Akiyama Masashi

JOURNAL OF DERMATOLOGY   Vol. 50 ( 6 ) page： 833 - 836   2023.6

Abdominal pain accompanied by elevated serum inflammatory markers and biliary enzymes for diagnosing immune checkpoint inhibitor-induced sclerosing cholangitis.

Yamamoto T, Mizuno K, Ito T, Yokoyama S, Yamamoto K, Imai N, Ishizu Y, Honda T, Ishikawa T, Kanamori A, Yasuda S, Toyoda H, Yokota K, Hase T, Nishio N, Maeda O, Ishii M, Sone M, Ando Y, Akiyama M, Ishigami M, Kawashima H

Investigational new drugs   Vol. 41 ( 3 ) page： 512 - 521   2023.6

Targeting IL-36 in Inflammatory Skin Diseases

Fukaura Ryo, Akiyama Masashi

BIODRUGS   Vol. 37 ( 3 ) page： 279 - 293   2023.5

Involvement of hypoxia-inducible factor activity in inevitable air-exposure treatment upon differentiation in a three-dimensional keratinocyte culture

Teshima Hirofumi, Endo Mayuko, Furuyama Yumea, Takama Hiroyuki, Akiyama Masashi, Tsuji Tokuji, Tatsukawa Hideki, Hitomi Kiyotaka

FEBS JOURNAL   Vol. 290 ( 8 ) page： 2049 - 2063   2023.4

Successful treatment of rapid progressive interstitial lung disease in a case of anti-Zo antibody positive anti-synthetase syndrome

Koizumi Haruka, Muro Yoshinao, Kamiya Satoshi, Akashi Norika, Imai Satoko, Yamashita Yuta, Ogawa-Momohara Mariko, Takeichi Takuya, Akiyama Masashi

INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES   Vol. 26 ( 9 ) page： 1872 - 1873   2023.3

Multiple diagnostic examinations are effective for the early diagnosis of scrofuloderma.

Ueno E, Murase C, Fukaura R, Adachi R, Mori S, Suzuki Y, Tetsuka N, Akiyama M

Clinical medicine (London, England)   Vol. 23 ( 2 ) page： 179 - 181   2023.3

A case of advanced diffuse large B-cell lymphoma diagnosed from widespread superficial mycosis of the skin

Suzuki Yuika, Murase Chiaki, Ushijima Yoko, Hanai Yuriko, Ogawa Yasushi, Toyama Takanori, Akiyama Masashi

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY   Vol. 37 ( 6 ) page： e779 - e781   2023.2

Current understanding of the phenotypic spectrum of patients with NLRP1 variants.

Takeichi T, Akiyama M

The British journal of dermatology   Vol. 188 ( 2 ) page： 160 - 167   2023.2

Prominent dermal accumulation of Russell bodies underlying pseudocarcinomatous hyperplasia with fungal infection

Noda Tatsuhiro, Akashi Norika, Shimomura Maiko, Koizumi Haruka, Mizuta Miyuki, Nakajima Kosei, Takeichi Takuya, Mitsuma Teruyuki, Akiyama Masashi

NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 85 ( 1 ) page： 123 - 126   2023.2

FLG mutations, eczema control, and respiratory symptom at one-year-old in early-onset atopic dermatitis infants (PACI-ON cohort study).

Kumagai F, Yamamoto-Hanada K, Saito-Abe M, Sato M, Ishikawa F, Irahara M, Miyaji Y, Kabashima S, Ohya Y, Akiyama M, Kono M

Journal of dermatological science   Vol. 109 ( 2 ) page： 99 - 101   2023.2

Clustering using unsupervised machine learning to stratify the risk of immune-related liver injury

Yamamoto Takafumi, Morooka Hikaru, Ito Takanori, Ishigami Masatoshi, Mizuno Kazuyuki, Yokoyama Shinya, Yamamoto Kenta, Imai Norihiro, Ishizu Yoji, Honda Takashi, Yokota Kenji, Hase Tetsunari, Maeda Osamu, Hashimoto Naozumi, Ando Yuichi, Akiyama Masashi, Kawashima Hiroki

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 38 ( 2 ) page： 251 - 258   2023.2

Ichthyotic skin lesions of Conradi-Hunermann-Happle syndrome successfully treated with dupilumab

Fukaura Ryo, Takeichi Takuya, Ebata Aoi, Murase Chiaki, Muro Yoshinao, Akiyama Masashi

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY   Vol. 37 ( 6 ) page： e732 - e734   2023.1

English version of Japanese guidance for the use of oral Janus kinase (JAK) inhibitors in the treatments of atopic dermatitis

Saeki Hidehisa, Akiyama Masashi, Abe Masatoshi, Igarashi Atsuyuki, Imafuku Shinichi, Ohya Yukihiro, Katoh Norito, Kameda Hideto, Kabashima Kenji, Tsunemi Yuichiro, Hide Michihiro, Ohtsuki Mamitaro

JOURNAL OF DERMATOLOGY   Vol. 50 ( 1 ) page： E1 - E19   2023.1

Appropriate immunoassay systems are needed to evaluate various anticentromere antibodies as biomarkers for disease progression in systemic sclerosis

Muro Yoshinao, Yamashita Yuta, Koizumi Haruka, Takeichi Takuya, Akiyama Masashi, Ogawa-Momohara Mariko

JOURNAL OF IMMUNOLOGICAL METHODS   Vol. 512   page： 113400   2023.1

Exploring biomarkers to predict clinical improvement of atopic dermatitis in patients treated with dupilumab (B-PAD study)

Nakahara Takeshi, Izuhara Kenji, Onozuka Daisuke, Saeki Hidehisa, Nunomura Satoshi, Takenaka Motoi, Matsumoto Mai, Kataoka Yoko, Fujimoto Rai, Kaneko Sakae, Morita Eishin, Tanaka Akio, Hide Michihiro, Okano Tatsuro, Miyagaki Tomomitsu, Aoki Natsuko, Nakajima Kimiko, Ichiyama Susumu, Kido-Nakahara Makiko, Tonomura Kyoko, Nakagawa Yukinobu, Tamagawa-Mineoka Risa, Masuda Koji, Takeichi Takuya, Akiyama Masashi, Ishiuji Yozo, Katsuta Michie, Kinoshita Yuki, Tateishi Chiharu, Yamamoto Aya, Morita Akimichi, Matsuda-Hirose Haruna, Hatano Yutaka, Kawasaki Hiroshi, Tanese Keiji, Ohtsuki Mamitaro, Kamiya Koji, Kabata Yudai, Abe Riichiro, Mitsui Hiroshi, Kawamura Tatsuyoshi, Tsuji Gaku, Katoh Norito, Furue Masutaka

CLINICAL AND EXPERIMENTAL ALLERGY   Vol. 53 ( 2 ) page： 233 - 238   2022.12

Application of nanopore sequencing in identifying null mutations and intragenic copy number variations in filaggrin gene

Chang Y., Lin Y., Chiu F., Akiyama M., Hsu C.

JOURNAL OF INVESTIGATIVE DERMATOLOGY   Vol. 142 ( 12 ) page： S230 - S230   2022.12

Whole-exome sequencing reveals a retinitis pigmentosa-causative PRPH2 variant as a secondary finding in a patient with pseudoxanthoma elasticum

Miyazaki Akira, Takeichi Takuya, Tanahashi Kana, Taki Tomoki, Taki Yosuke, Muro Yoshinao, Akiyama Masashi

JOURNAL OF DERMATOLOGY   Vol. 50 ( 2 ) page： e85 - e86   2022.10

Novel homozygous missense mutation c.1654G&gt;T in the ALOX12B gene causing congenital ichthyosiform erythroderma.

Mae K, Kawakami Y, Kajita A, Takeichi T, Noda T, Hirai Y, Akiyama M, Morizane S

The Journal of dermatology     2022.10

Comment on: Disease evolution in a long-term follow-up of 104 undifferentiated connective tissue disease patients.

Yamashita Y, Muro Y, Koizumi H, Ogawa-Momohara M, Takeichi T, Akiyama M

Clinical and experimental rheumatology     2022.10

Postoperative radiation therapy improves prognoses in extramammary Paget's disease presenting with multiple lymph node metastases.

Okumura M, Ogata D, Namikawa K, Tsutsui K, Takahashi A, Okuma K, Kashihara T, Igaki H, Akiyama M, Yamazaki N

The Journal of dermatology   Vol. 49 ( 10 ) page： 1005 - 1011   2022.10

A case of juvenile amyopathic dermatomyositis with anti-transcription intermediary factor 1-α antibody showing negative anti-TIF1-γ ELISA results: Comment on "Case of pembrolizumab-induced dermatomyositis with anti-transcription intermediary factor 1-γ antibody".

Koizumi H, Muro Y, Imai S, Yamashita Y, Ogawa-Momohara M, Takeichi T, Murakami M, Mitsuma T, Akiyama M

The Journal of dermatology     2022.9

Application of nanopore sequencing in identifying null mutations and intragenic copy number variations (CNVs) in FLG.

Lin YC, Chang YH, Chiu FP, Akiyama M, Hsu CK

Journal of dermatological science     2022.9

Development of pemphigus vegetans and exacerbation of pemphigus foliaceus after secukinumab loading in a patient with complicated generalized pustular psoriasis and pyoderma gangrenosum.

Minai L, Takeichi T, Ogawa Y, Honobe-Tabuchi A, Okamoto T, Mitsui H, Shimada S, Akiyama M, Kawamura T

The Journal of dermatology     2022.9

Ceramide profiling of stratum corneum in Sjögren-Larsson syndrome.

Arai A, Takeichi T, Wakamoto H, Sassa T, Ito Y, Murase Y, Ogi T, Akiyama M, Kihara A

Journal of dermatological science   Vol. 107 ( 3 ) page： 114 - 122   2022.9

Neutrophil extracellular traps are involved in enhanced contact hypersensitivity response in IL-36 receptor antagonist-deficient mice.

Hasegawa Y, Iwata Y, Fukushima H, Tanaka Y, Watanabe S, Saito K, Ito H, Sugiura M, Akiyama M, Sugiura K

Scientific reports   Vol. 12 ( 1 ) page： 13384   2022.8

Comment on: Favourable complete remission of anti-OJ antibody-positive myositis after lung cancer resection.

Muro Y, Nishida K, Yamashita Y, Koizumi H, Takeichi T, Satoh M, Akiyama M

Rheumatology (Oxford, England)   Vol. 61 ( 8 ) page： e232 - e234   2022.8

Darier disease successfully treated with a topical agent containing vitamin A (retinyl palmitate), vitamin E, and urea.

Miyazaki A, Taki T, Takeichi T, Kono M, Yagi H, Akiyama M

The Journal of dermatology   Vol. 49 ( 8 ) page： 779 - 782   2022.8

Extremely mild dominant dystrophic epidermolysis bullosa: Genotype information from whole-exome sequencing of salivary gDNA predicts disease severity.

Miyazaki A, Takeichi T, Takeuchi S, Taki T, Muro Y, Akiyama M

The Journal of dermatology   Vol. 49 ( 8 ) page： e276 - e277   2022.8

Eosinophilic granulomatosis with polyangiitis complicated with idiopathic thrombocytopenic purpura and sclerosing cholangitis showing eosinophilic infiltration.

Yamashita Y, Takeichi T, Ishizu Y, Suzuki N, Tsuboi T, Matsuura K, Koizumi H, Muro Y, Akiyama M

The Journal of dermatology   Vol. 49 ( 8 ) page： e270 - e271   2022.8

Deep Phenotyping of Superficial Epidermolytic Ichthyosis due to a Recurrent Mutation in <i>KRT2</i>.

Suzuki Y, Takeichi T, Tanahashi K, Muro Y, Suga Y, Ogi T, Akiyama M

International journal of molecular sciences   Vol. 23 ( 14 )   2022.7

Clinical utility of botulinum toxin type A local injection therapy for head and forehead hyperhidrosis.

Ando Y, Ohshima Y, Yanagishita T, Watanabe H, Tamada Y, Akiyama M, Watanabe D

The Journal of dermatology   Vol. 49 ( 7 ) page： 719 - 723   2022.7

The interferon-β/STAT1 axis drives the collective invasion of skin squamous cell carcinoma with sealed intercellular spaces.

Kumagai Y, Nio-Kobayashi J, Ishihara S, Enomoto A, Akiyama M, Ichihara R, Haga H

Oncogenesis   Vol. 11 ( 1 ) page： 27   2022.5

Epithelioid cell granuloma formation in CARD14-associated papulosquamous eruptions

Takeichi T., Ikeda K., Muro Y., Ogi T., Morizane S., Akiyama M.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY   Vol. 36 ( 5 ) page： E369 - E371   2022.5

Cytomegalovirus-induced skin erosions mimicking bullous pemphigoid relapse

Shibata A, Mabuchi Y, Fukuzawa S, Akiyama M

European journal of dermatology : EJD   Vol. 32 ( 2 ) page： 272 - 273   2022.4

Case of ichthyosis with confetti caused by KRT10 mutation, complicated with multiple malignant melanomas.

Ito Y, Takeichi T, Nakagawa K, Tanahashi K, Muro Y, Ogi T, Akiyama M

The Journal of dermatology     2022.3

Symmetrical peripheral gangrene in a patient with septic shock due to Serratia marcescens.

Okochi S, Murase C, Akiyama M

The Journal of dermatology     2022.3

Mutations in SAM syndrome and palmoplantar keratoderma patients suggest genotype/phenotype correlations in DSG1 mutations

Takeuchi S., Takeichi T., Koike Y., Takama H., Tanahashi K., Okuno Y., Ishii N., Muro Y., Ogi T., Suga Y., Akiyama M.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY   Vol. 36 ( 3 ) page： E215 - E218   2022.3

Understanding immune profiles in ichthyosis may lead to novel therapeutic targets.

Akiyama M

The Journal of allergy and clinical immunology     2022.2

Ichthyosis Scoring System-A Powerful Tool in the Era of Immune Pathway-Targeted Therapies for Ichthyosis.

Akiyama M

JAMA dermatology     2022.2

Cutaneous ischemia-reperfusion injury is exacerbated by IL-36 receptor antagonist deficiency

Tanaka Y., Iwata Y., Saito K., Fukushima H., Watanabe S., Hasegawa Y., Akiyama M., Sugiura K.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY   Vol. 36 ( 2 ) page： 295 - 304   2022.2

UVB-Induced Skin Autoinflammation Due to <i>Nlrp1b</i> Mutation and Its Inhibition by Anti-IL-1β Antibody.

Murase Y, Takeichi T, Koseki J, Miyasaka Y, Muro Y, Ohno T, Shimamura T, Akiyama M

Frontiers in immunology   Vol. 13   page： 876390   2022

Autoinflammatory keratinization diseases: The concept, diseases involved, and pathogeneses

Akiyama Masashi

DERMATOLOGICA SINICA   Vol. 40 ( 4 ) page： 197 - 203   2022

Case of harlequin ichthyosis in preterm infant with a compound heterozygous ABCA12 missense mutation.

Miyazaki M, Ohkawa N, Miyabayashi K, Shoji H, Takeichi T, Kantake M, Akiyama M, Shimizu T

The Journal of dermatology     2021.12

Nodular fasciitis with prominent myxoid changes on the face.

Ito E, Masaki S, Akiyama M

The Journal of dermatology     2021.11

Pustular psoriasis as an autoinflammatory keratinization disease (AiKD): Genetic predisposing factors and promising therapeutic targets.

Akiyama M

Journal of dermatological science     2021.11

Increased risk of thyroid dysfunction by PD-1 and CTLA-4 blockade in patients without thyroid autoantibodies at baseline.

Iwama S, Kobayashi T, Yasuda Y, Okuji T, Ito M, Ando M, Zhou X, Yamagami A, Onoue T, Kawaguchi Y, Miyata T, Sugiyama M, Takagi H, Hagiwara D, Suga H, Banno R, Hase T, Morise M, Wakahara K, Yokota K, Kato M, Nishio N, Tanaka C, Miyata K, Ogura A, Ito T, Sawada T, Shimokata T, Niimi K, Ohka F, Ishigami M, Gotoh M, Hashimoto N, Saito R, Kiyoi H, Kajiyama H, Ando Y, Hibi H, Sone M, Akiyama M, Kodera Y, Arima H

The Journal of clinical endocrinology and metabolism     2021.11

Clinical characteristics of gastrointestinal immune-related adverse events of immune checkpoint inhibitors and their association with survival.

Yamada K, Sawada T, Nakamura M, Yamamura T, Maeda K, Ishikawa E, Iida T, Mizutani Y, Kakushima N, Ishikawa T, Furukawa K, Ohno E, Honda T, Kawashima H, Ishigami M, Furune S, Hase T, Yokota K, Maeda O, Hashimoto N, Akiyama M, Ando Y, Fujishiro M

World journal of gastroenterology   Vol. 27 ( 41 ) page： 7190 - 7206   2021.11

Pitfalls in establishing mouse model of female infertility by immunization with human centromere protein.

Muro Y, Yamashita Y, Koizumi H, Takeichi T, Akiyama M

Immunology letters   Vol. 239   page： 20 - 22   2021.11

A case of generalised pustular psoriasis with bullous pemphigoid showing spongiform pustule of Kogoj with eosinophils.

Nozaki H, Iinuma S, Komatsu S, Hashimoto Y, Shibaki H, Takeichi T, Ishii N, Akiyama M, Honma M, Ishida-Yamamoto A

European journal of dermatology : EJD   Vol. 31 ( 5 ) page： 660 - 662   2021.10

Clinical course of liver injury induced by immune checkpoint inhibitors in patients with advanced malignancies.

Ito T, Ishigami M, Yamamoto T, Mizuno K, Yamamoto K, Imai N, Ishizu Y, Honda T, Kawashima H, Yasuda S, Toyoda H, Yokota K, Hase T, Nishio N, Maeda O, Kato M, Hashimoto N, Hibi H, Kodera Y, Sone M, Ando Y, Akiyama M, Shimoyama Y, Fujishiro M

Hepatology international   Vol. 15 ( 5 ) page： 1278 - 1287   2021.10

Differential Pathomechanisms of Desmoglein 1 Transmembrane Domain Mutations in Skin Disease.

Zimmer SE, Takeichi T, Conway DE, Kubo A, Suga Y, Akiyama M, Kowalczyk AP

The Journal of investigative dermatology     2021.8

Updated allele frequencies of SERPINB7 founder mutations in Asian patients with Nagashima-type palmoplantar keratosis/keratoderma.

Ito Y, Takeichi T, Ikeda K, Tanahashi K, Yoshikawa T, Murase Y, Muro Y, Kawakami Y, Nakamura Y, Matsuyama K, Muto J, Oiso N, Morizane S, Sugiura K, Suga Y, Seishima M, Kawada A, Ogi T, Akiyama M

Journal of dermatological science   Vol. 103 ( 2 ) page： 116 - 119   2021.8

Intravenous allogeneic multilineage-differentiating stress-enduring cells in adults with dystrophic epidermolysis bullosa: a phase 1/2 open-label study

Fujita Y., Nohara T., Takashima S., Natsuga K., Adachi M., Yoshida K., Shinkuma S., Takeichi T., Nakamura H., Wada O., Akiyama M., Ishiko A., Shimizu H.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY   Vol. 35 ( 8 ) page： E528 - E531   2021.8

Clinical significance of anti-NOR90 antibodies in systemic sclerosis and idiopathic interstitial pneumonia.

Yamashita Y, Yamano Y, Muro Y, Ogawa-Momohara M, Takeichi T, Kondoh Y, Akiyama M

Rheumatology (Oxford, England)     2021.7

Low plasma fibrinogen levels are associated with poor prognosis in cutaneous angiosarcoma of the head and neck.

Mori S, Taki T, Murakami Y, Urata T, Okumura M, Akanabe H, Ebata A, Imai S, Yokota K, Akiyama M

Cancer science     2021.7

Paradoxical Reaction in a Patient with Hidradenitis Suppurativa Undergoing Adalimumab Treatment.

Ikeya S, Takeichi T, Taki T, Muro Y, Ogi T, Akiyama M

Acta dermato-venereologica   Vol. 101 ( 6 ) page： adv00484   2021.6

Japanese guidelines for the management of palmoplantar keratoderma.

Yoneda K, Kubo A, Nomura T, Ishida-Yamamoto A, Suga Y, Akiyama M, Kanazawa N, Hashimoto T, Committee on Guidelines for the Management of PPKs.

The Journal of dermatology     2021.6

Case of annular pustular psoriasis/circinate erythematous psoriasis induced by hydroxychloroquine in a patient with systemic lupus erythematosus: Possible association with CARD-14 mutation.

Midorikawa H, Kiniwa Y, Minagawa A, Osawa K, Shirai T, Sano T, Nakamura K, Ashida A, Ueno KI, Takeichi T, Akiyama M, Okuyama R

The Journal of dermatology     2021.6

Hereditary Mucoepithelial Dysplasia and Autosomal-Dominant IFAP Syndrome Is a Clinical Spectrum Due to SREBF1 Variants.

Murase C, Takeichi T, Nomura T, Ogi T, Akiyama M

The Journal of investigative dermatology   Vol. 141 ( 6 ) page： 1596 - 1598   2021.6

Isolated autosomal recessive woolly hair/hypotrichosis: genetics, pathogenesis and therapies.

Akiyama M

Journal of the European Academy of Dermatology and Venereology : JEADV     2021.5

Subcutaneous giant trichoblastoma in the abdomen.

Goto K, Kono M, Urata T, Hasegawa-Murakami Y, Matsumoto T, Yamashita Y, Yokota K, Akiyama M

The Journal of dermatology     2021.5

Cutaneous malignant melanoma in an elderly patient with intermediate junctional epidermolysis bullosa.

Yamashita Y, Taki T, Takeichi T, Okumura M, Mori S, Ito Y, Ogi T, Yamada M, Akiyama M

The Journal of dermatology     2021.5

A case of adolescent striae distensae accompanied by ileitis

Shibata Tomoyuki, Takama Hiroyuki, Oshima Yuichiro, Kono Michihiro, Akiyama Masashi, Watanabe Daisuke

JOURNAL OF DERMATOLOGY   Vol. 48 ( 5 ) page： E219 - E220   2021.5

MEDNIK-like syndrome due to compound heterozygous mutations in AP1B1

Ito Y., Takeichi T., Igari S., Mori T., Ono A., Suyama K., Takeuchi S., Muro Y., Ogi T., Hosoya M., Yamamoto T., Akiyama M.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY   Vol. 35 ( 5 ) page： E345 - E347   2021.5

Immediate response to apremilast in patients with palmoplantar pustulosis: a retrospective pilot study

Kato Noriko, Takama Hiroyuki, Ando Yoriko, Yanagishita Takeshi, Ohshima Yuichiro, Ohashi Wataru, Akiyama Masashi, Watanabe Daisuke

INTERNATIONAL JOURNAL OF DERMATOLOGY   Vol. 60 ( 5 ) page： 570 - 578   2021.5

Successful dupilumab treatment for ichthyotic and atopic features of Netherton syndrome.

Murase C, Takeichi T, Taki T, Yoshikawa T, Suzuki A, Ogi T, Suga Y, Akiyama M

Journal of dermatological science   Vol. 102 ( 2 ) page： 126 - 129   2021.5

Odontogenic keratocysts are an important clue for diagnosing basal cell nevus syndrome.

Kaibuchi-Ando K, Takeichi T, Ito Y, Takeuchi S, Yamashita Y, Yamada M, Muro Y, Ogi T, Akiyama M

Nagoya journal of medical science   Vol. 83 ( 2 ) page： 393 - 396   2021.5

Pathogenic and Compensatory Mechanisms in Epidermis of Sphingomyelin Synthase 2-Deficient Mice.

Sakai S, Makino A, Nishi A, Ichikawa T, Yamashita T, Taniguchi M, Tokudome Y, Hirabayashi Y, Akiyama M, Crumrine D, Uchida Y, Elias PM, Tsuchida T, Hamanaka S

Skin pharmacology and physiology     page： 1 - 7   2021.4

Identification of a novel causative mutation in KRT1 in diffuse palmoplantar keratoderma, facilitated by whole-exome sequencing.

Takeuchi S, Takeichi T, Ito Y, Tanahashi K, Muro Y, Ogi T, Akiyama M

European journal of dermatology : EJD   Vol. 31 ( 2 ) page： 264 - 265   2021.4

Acylceramide is a key player in skin barrier function: insight into the molecular mechanisms of skin barrier formation and ichthyosis pathogenesis

Akiyama Masashi

FEBS JOURNAL   Vol. 288 ( 7 ) page： 2119 - 2130   2021.4

Cutaneous extramedullary hematopoiesis in a patient with secondary myelofibrosis due to MPL gene mutation

Murase Y., Takeichi T., Tanahashi K., Marumo Y., Suzuki Y., Nakamura S., Akiyama M.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY   Vol. 35 ( 4 ) page： E257 - E259   2021.4

Darier's disease with epilepsy in an elderly patient after surgery for aortic dissection

Murase Yuya, Takeichi Takuya, Shibata Tomoyuki, Muro Yoshinao, Akiyama Masashi

JOURNAL OF DERMATOLOGY   Vol. 48 ( 4 ) page： E169 - E170   2021.4

Acute generalized exanthematous pustulosis triggered by acetaminophen in an IL36RN variant heterozygote

Murase Chiaki, Takeichi Takuya, Sugiura Kazumitsu, Akiyama Masashi

JOURNAL OF DERMATOLOGY   Vol. 48 ( 4 ) page： E186 - E187   2021.4

ANCA-associated neuropathy in systemic sclerosis: A case report and review of literature

Takenaka Kayo, Takeichi Takuya, Nishi Ryoji, Suzuki Masashi, Koike Haruki, Katsuno Masahisa, Ogawa-Momohara Mariko, Muro Yoshinao, Akiyama Masashi

JOURNAL OF CUTANEOUS IMMUNOLOGY AND ALLERGY   Vol. 4 ( 2 ) page： 34 - 36   2021.4

Two Cases of Porokeratosis with MVD Mutations, in Association with Bullous Pemphigoid.

Arisawa Y, Ito Y, Tanahashi K, Muro Y, Ogi T, Takeichi T, Akiyama M

Acta dermato-venereologica   Vol. 101 ( 3 ) page： adv00423   2021.3

Morphea in a Crohn's disease patient undergoing ustekinumab treatment.

Makihara-Inukai M, Takeichi T, Ogawa-Momohara M, Muro Y, Akiyama M

European journal of dermatology : EJD   Vol. 31 ( 1 ) page： 96 - 97   2021.2

Neutrophil/lymphocyte ratio as a predictor of lymph node metastasis in extramammary Paget disease: A retrospective study.

Ebata A, Taki T, Mori S, Murakami Y, Urata T, Okumura M, Akanabe H, Imai S, Yokota K, Akiyama M

Journal of the American Academy of Dermatology     2021.1

A case with overlapping features of IgG4-related autoimmune pancreatitis, Sjögren's syndrome and anti-aminoacyl-tRNA synthetase syndrome.

  Vol. 5 ( 1 ) page： 82-86   2021.1

Generalized pustular psoriasis associated with systemic lupus erythematosus successfully treated with secukinumab

Akaji Kazuya, Nakagawa Yukinobu, Kakuda Kasumi, Takafuji Madoka, Kiyohara Eiji, Murase Chiaki, Takeichi Takuya, Akiyama Masashi, Fujimoto Manabu

JOURNAL OF DERMATOLOGY   Vol. 48 ( 1 ) page： E43 - E44   2021.1

Whole-exome sequencing and host cell reactivation assay lead to a diagnosis of xeroderma pigmentosum group D with mild ultraviolet radiation sensitivity.

Sugaya M, Funamizu K, Kono M, Okuno Y, Kondo T, Ono R, Akiyama M, Nishigori C, Sato S

The Journal of dermatology   Vol. 48 ( 1 ) page： 96 - 100   2021.1

Systemic inflammatory diseases due to germ line EGFR mutations, with features suggestive of autoinflammatory keratinization diseases

Takeichi Takuya, Akiyama Masashi

JOURNAL OF DERMATOLOGY   Vol. 48 ( 1 ) page： E24 - E25   2021.1

A patient with CARD14-associated papulosquamous eruptions showing atopic dermatitis-like features

Takeichi T., Terawaki S., Kubota Y., Ito Y., Tanahashi K., Muro Y., Akiyama M.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY   Vol. 35 ( 1 ) page： E58 - E59   2021.1

Autoinflammatory Keratinization Disease With Hepatitis and Autism Reveals Roles for JAK1 Kinase Hyperactivity in Autoinflammation.

Takeichi T, Lee JYW, Okuno Y, Miyasaka Y, Murase Y, Yoshikawa T, Tanahashi K, Nishida E, Okamoto T, Ito K, Muro Y, Sugiura K, Ohno T, McGrath JA, Akiyama M

Frontiers in immunology   Vol. 12   page： 737747   2021

Clinical practice guide for the treatment of perforating dermatosis.

Kawakami T, Akiyama M, Ishida-Yamamoto A, Nakano H, Mitoma C, Yoneda K, Suga Y

The Journal of dermatology   Vol. 47 ( 12 ) page： 1374 - 1382   2020.12

Neutrophil extracellular traps are induced in a psoriasis model of interleukin-36 receptor antagonist-deficient mice

Watanabe Soichiro, Iwata Yohei, Fukushima Hidehiko, Saito Kenta, Tanaka Yoshihito, Hasegawa Yurie, Akiyama Masashi, Sugiura Kazumitsu

SCIENTIFIC REPORTS   Vol. 10 ( 1 ) page： 20149   2020.11

A heterozygous SERPINB7 mutation is a possible modifying factor for epidermolytic palmoplantar keratoderma.

Yoshikawa T, Takeichi T, Ogi T, Suga Y, Muro Y, Akiyama M

Journal of dermatological science   Vol. 100 ( 2 ) page： 148 - 151   2020.11

Anti-Zo antibodies in Japanese myositis patients detected by a newly developed ELISA.

Muro Y, Hashimoto T, Izumi S, Ogawa-Momohara M, Takeichi T, Yamashita H, Yasuoka H, Akiyama M

Clinical and experimental rheumatology     page： .   2020.10

Acquired reactive perforating collagenosis with chondrodermatitis nodularis chronica helicis

Murase Yuya, Takeichi Takuya, Tanahashi Kana, Takama Hiroyuki, Akiyama Masashi

JOURNAL OF DERMATOLOGY   Vol. 47 ( 10 ) page： E362 - E364   2020.10

Classical Vohwinkel syndrome with heterozygous p.Asp66His mutation in GJB2 gene: Second Asian case

Ikeda Kenta, Takeichi Takuya, Ito Yasutoshi, Kawakami Yoshio, Nakagawa Yuki, Naito Seiko, Yamasaki Osamu, Akiyama Masashi, Morizane Shin

JOURNAL OF DERMATOLOGY   Vol. 47 ( 10 ) page： E352 - E354   2020.10

Successful treatment with i.v. immunoglobulin and rituximab for bronchiolitis obliterans associated with paraneoplastic pemphigus.

Kaibuchi-Ando K, Sugiura K, Muro Y, Takahashi Y, Kojima S, Ishii N, Hashimoto T, Akiyama M

The Journal of dermatology   Vol. 47 ( 10 ) page： E368 - E370   2020.10

Reducing immunosuppressant use in patients with chronic inflammation during the COVID-19 pandemic: Risks versus benefits

Ogawa-Momohara Mariko, Muro Yoshinao, Takeichi Takuya, Akiyama Masashi

JOURNAL OF CUTANEOUS IMMUNOLOGY AND ALLERGY   Vol. 3 ( 5 ) page： 120-121   2020.10

Clinical and serological features of dermatomyositis and systemic lupus erythematosus patients with autoantibodies to ADAR1.

Muro Y, Ogawa-Momohara M, Takeichi T, Fukaya S, Yasuoka H, Kono M, Akiyama M

Journal of dermatological science   Vol. 100 ( 1 ) page： 82 - 84   2020.10

Myocardial Vasculitis Associated With the Immune Checkpoint Inhibitor Pembrolizumab.

Oishi H, Morimoto R, Shimoyama Y, Kuroda K, Urata T, Kondo T, Okumura T, Bando YK, Akiyama M, Murohara T

JACC. Case reports   Vol. 2 ( 12 ) page： 1937 - 1941   2020.10

Exploration of biomarkers to predict clinical improvement of atopic dermatitis in patients treated with dupilumab: A study protocol.

Nakahara T, Izuhara K, Onozuka D, Nunomura S, Tamagawa-Mineoka R, Masuda K, Ichiyama S, Saeki H, Kabata Y, Abe R, Ohtsuki M, Kamiya K, Okano T, Miyagaki T, Ishiuji Y, Asahina A, Kawasaki H, Tanese K, Mitsui H, Kawamura T, Takeichi T, Akiyama M, Nishida E, Morita A, Tonomura K, Nakagawa Y, Sugawara K, Tateishi C, Kataoka Y, Fujimoto R, Kaneko S, Morita E, Tanaka A, Hide M, Aoki N, Sano S, Matsuda-Hirose H, Hatano Y, Takenaka M, Murota H, Katoh N, Furue M

Medicine   Vol. 99 ( 38 ) page： e22043   2020.9

IL-36 receptor antagonist deficiency resulted in delayed wound healing due to excessive recruitment of immune cells

Saito Kenta, Iwata Yohei, Fukushima Hidehiko, Watanabe Soichiro, Tanaka Yoshihito, Hasegawa Yurie, Akiyama Masashi, Sugiura Kazumitsu

SCIENTIFIC REPORTS   Vol. 10 ( 1 ) page： 14772   2020.9

Mild epidermolytic ichthyosis with palmoplantar keratoderma due to the KRT1 mutation p.lle479Thr.

Murase Y, Tanahashi K, Takeichi T, Sugiura K, Aiyama A, Nishida K, Mitsuma T, Akiyama M

The Journal of dermatology   Vol. 47 ( 9 ) page： E336 - E339   2020.9

Editorial: Autoinflammatory Keratinization Disease (AiKD).

Akiyama M, De Vita V, Sugiura K

Frontiers in immunology   Vol. 11   page： 1753   2020.8

Mutations inFLG, the gene-coding profilaggrin/filaggrin, are associated with putative hay fever in patients with atopic dermatitis

Minakawa Satoko, Matsuzaki Yasushi, Suwa Hideyuki, Kono Michihiro, Akiyama Masashi, Sawamura Daisuke

JOURNAL OF CUTANEOUS IMMUNOLOGY AND ALLERGY   Vol. 3 ( 4 ) page： 98 - 100   2020.8

Late-onset Langerhans cell histiocytosis without extracutaneous involvement

Iwata Mai, Takeichi Takuya, Muro Yoshinao, Akiyama Masashi

JOURNAL OF CUTANEOUS IMMUNOLOGY AND ALLERGY   Vol. 3 ( 4 ) page： 94-95   2020.8

A case of late middle age-onset recurrent rheumatic fever

Shibata A., Yoshikawa T., Makita S., Muro Y., Akiyama M.

CLINICAL AND EXPERIMENTAL DERMATOLOGY   Vol. 45 ( 5 ) page： 595 - 596   2020.7

A single-centre cohort study on cutaneous manifestations of antinuclear matrix protein 2 antibody-positive dermatomyositis

Okochi S., Ogawa-Momohara M., Muro Y., Dittmer M. R., Akiyama M.

CLINICAL AND EXPERIMENTAL DERMATOLOGY   Vol. 45 ( 5 ) page： 591 - 593   2020.7

A case of pemphigus with anti-desmoglein 3 and anti-desmocollin 2 and 3 autoantibodies, associated with follicular lymphoma and bronchiolitis obliterans.

Yoshikawa M, Takeichi T, Taki T, Hayakawa F, Ishii N, Hashimoto T, Muro Y, Akiyama M

European journal of dermatology : EJD   Vol. 30 ( 4 ) page： 424 - 425   2020.7

Pathogenesis of a variant in the 5 ' untranslated region of ADAR1 in dyschromatosis symmetrica hereditaria

Suganuma Mutsumi, Kono Michihiro, Yamanaka Masayoshi, Akiyama Masashi

PIGMENT CELL & MELANOMA RESEARCH   Vol. 33 ( 4 ) page： 591 - 600   2020.7

Recurrent KRT10 Variant in Ichthyosis with Confetti.

Takeichi T, Suga Y, Mizuno T, Okuno Y, Ichikawa D, Kono M, Lee JYW, McGrath JA, Akiyama M

Acta dermato-venereologica   Vol. 100 ( 14 ) page： adv00209   2020.7

Annular Sarcoidosis with Geographic Appearance in a Patient with Systemic Sarcoidosis.

Takama H, Ohshima Y, Ando Y, Yanagishita T, Takahashi E, Tsuzuki T, Uchida K, Eishi Y, Akiyama M, Watanabe D

Acta dermato-venereologica   Vol. 100 ( 13 ) page： adv00182   2020.6

Real world data of liver injury induced by immune checkpoint inhibitors in Japanese patients with advanced malignancies

Mizuno Kazuyuki, Ito Takanori, Ishigami Masatoshi, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Kawashima Hiroki, Inukai Yosuke, Toyoda Hidenori, Yokota Kenji, Hase Tetsunari, Maeda Osamu, Kiyoi Hitoshi, Nagino Masato, Hibi Hideharu, Kodera Yasuhiro, Fujimoto Yasushi, Sone Michihiko, Gotoh Momokazu, Ando Yuichi, Akiyama Masashi, Hasegawa Yoshinori, Fujishiro Mitsuhiro

JOURNAL OF GASTROENTEROLOGY   Vol. 55 ( 6 ) page： 653 - 661   2020.6

Subacute cutaneous lupus erythematosus with melanocyte elimination induced by pembrolizumab.

Ogawa-Momohara M, Muro Y, Goto K, Obuse C, Satoh M, Kono M, Akiyama M

The Journal of dermatology   Vol. 47 ( 6 ) page： E217 - E219   2020.6

A systemic form chronic active Epstein-Barr virus infection diagnosed from erythema nodosum-like skin lesions.

Shibata A, Ishiguro Y, Makita S, Yamaga Y, Kimura H, Akiyama M

European journal of dermatology : EJD   Vol. 30 ( 3 ) page： 314 - 316   2020.5

Two cases of refractory nail psoriasis successfully treated with calcipotriol plus betamethasone dipropionate gel

Takama Hiroyuki, Ando Yoriko, Yanagishita Takeshi, Ohshima Yuichiro, Akiyama Masashi, Watanabe Daisuke

JOURNAL OF DERMATOLOGY   Vol. 47 ( 5 ) page： E211 - E213   2020.5

KLICK Syndrome Linked to a POMP Mutation Has Features Suggestive of an Autoinflammatory Keratinization Disease

Takeichi Takuya, Akiyama Masashi

FRONTIERS IN IMMUNOLOGY   Vol. 11   page： 641   2020.4

Generalized Pustular Psoriasis: Clinical Management and Update on Autoinflammatory Aspects

Takeichi Takuya, Akiyama Masashi

AMERICAN JOURNAL OF CLINICAL DERMATOLOGY   Vol. 21 ( 2 ) page： 227 - 236   2020.4

Anti-thyroid antibodies and thyroid echo pattern at baseline as risk factors for thyroid dysfunction induced by anti-programmed cell death-1 antibodies: a prospective study

Okada Norio, Iwama Shintaro, Okuji Takayuki, Kobayashi Tomoko, Yasuda Yoshinori, Wada Eri, Onoue Takeshi, Goto Motomitsu, Sugiyama Mariko, Tsunekawa Taku, Takagi Hiroshi, Hagiwara Daisuke, Ito Yoshihiro, Suga Hidetaka, Banno Ryoichi, Hase Tetsunari, Morise Masahiro, Kanda Mitsuro, Yokota Kenji, Hashimoto Naozumi, Ando Masahiko, Fujimoto Yasushi, Nagino Masato, Kodera Yasuhiro, Fujishiro Mitsuhiro, Hibi Hideharu, Sone Michihiko, Kiyoi Hitoshi, Gotoh Momokazu, Ando Yuichi, Akiyama Masashi, Hasegawa Yoshinori, Arima Hiroshi

BRITISH JOURNAL OF CANCER   Vol. 122 ( 6 ) page： 771 - 777   2020.3

Deep phenotyping of ichthyosis follicularis with atrichia and photophobia syndrome associated with MBTPS2 mutations

Murase Chiaki, Takeichi Takuya, Okuno Yusuke, Ikumi Kyoko, Morita Akimichi, Akiyama Masashi

JOURNAL OF DERMATOLOGY   Vol. 47 ( 3 ) page： E87 - E88   2020.3

Successful secukinumab treatment of recalcitrant juvenile generalized pustular psoriasis.

Nishida M, Takeichi T, Kono M, Imanishi A, Maekawa N, Akiyama M, Fukai K

The Journal of dermatology   Vol. 47 ( 3 ) page： E77 - E78   2020.3

sQUIZ your knowledge: Multiple subcutaneous nodules symmetrically located on tendinous regions

Hokari Naohiro, Ogawa-Momohara Mariko, Akiyama Masashi

EUROPEAN JOURNAL OF DERMATOLOGY   Vol. 30 ( 2 ) page： 226 - 227   2020.3

Pembrolizumab-induced psoriasis vulgaris successfully treated with apremilast

Takama Hiroyuki, Shibata Tomoyuki, Ando Yoriko, Yanagishita Takeshi, Ohshima Yuichiro, Akiyama Masashi, Watanabe Daisuke

EUROPEAN JOURNAL OF DERMATOLOGY   Vol. 30 ( 2 ) page： 188 - 190   2020.3

Autoinflammatory Keratinization Diseases (AiKDs): Expansion of Disorders to Be Included

Akiyama Masashi

FRONTIERS IN IMMUNOLOGY   Vol. 11   page： 280   2020.2

A case of brain metastasis in HER2-negative extramammary Paget's disease.

Maki-Inoue Y, Takeichi T, Sawada M, Fujitani S, Ohashi A, Akiyama M

European journal of dermatology : EJD     2020.2

Child case of Buruli ulcer successfully treated through a school-based skin survey project in Cote d'Ivoire

Yotsu Rie R., Murase Chiaki, N'Guessan Konan, Yao Aubin, Kouadio Kouame, N'Golo David Coulibaly, N'Guetta Aka, Akiyama Masashi, Constance Kadio, Vagamon Bamba

JOURNAL OF DERMATOLOGY   Vol. 47 ( 2 ) page： E64 - E65   2020.2

Multifaceted Analyses of Epidermal Serine Protease Activity in Patients with Atopic Dermatitis.

Nomura H, Suganuma M, Takeichi T, Kono M, Isokane Y, Sunagawa K, Kobashi M, Sugihara S, Kajita A, Miyake T, Hirai Y, Yamasaki O, Akiyama M, Morizane S

International journal of molecular sciences   Vol. 21 ( 3 )   2020.2

TAK-242 ameliorates contact dermatitis exacerbated by IL-36 receptor antagonist deficiency

Fukushima Hidehiko, Iwata Yohei, Watanabe Soichiro, Saito Kenta, Tanaka Yoshihito, Hasegawa Yurie, Akiyama Masashi, Sugiura Kazumitsu

SCIENTIFIC REPORTS   Vol. 10 ( 1 ) page： 734   2020.1

A juvenile male case of dermatofibrosarcoma protuberans on the breast

Murase Y., Takeichi T., Matsumoto T., Sakakibara A., Akiyama M.

CLINICAL AND EXPERIMENTAL DERMATOLOGY   Vol. 45 ( 1 ) page： 111 - 113   2020.1

A patient with bullous pemphigoid with mucosal involvement serologically positive for anti-BP230 autoantibodies only

Taki T., Takeichi T., Kono M., Sugiura K., Sugimura Y., Ishii N., Hashimoto T., Akiyama M.

BRITISH JOURNAL OF DERMATOLOGY   Vol. 182 ( 1 ) page： 221 - 223   2020.1

Unique reticular hyperkeratotic eruptions seen in a patient with Darier's disease and attention deficit hyperactivity disorder

Yoshikawa T., Takeichi T., Suga Y., Kitajima Y., Akiyama M.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY   Vol. 34 ( 1 ) page： E41 - E43   2020.1

Remodelling of calcinosis cutis in a patient with scleroderma overlap syndrome

Dittmer M. R., Ogawa-Momohara M., Muro Y., Kono M., Akiyama M.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY   Vol. 34 ( 1 ) page： E20 - E21   2020.1

Atopic dermatitis without serum immunoglobulin E elevation or loss-of-function filaggrin gene mutation in a patient with X-linked agammaglobulinemia

Yamazaki Emi, Kikuchi Katsuko, Sasahara Yoji, Kono Michihiro, Akiyama Masashi, Aiba Setsuya

JOURNAL OF DERMATOLOGY   Vol. 47 ( 1 ) page： 58 - 60   2020.1

Reduced stratum corneum acylceramides in autosomal recessive congenital ichthyosis with a NIPAL4 mutation

Murase Yuya, Takeichi Takuya, Kawamoto Akane, Tanahashi Kana, Okuno Yusuke, Takama Hiroyuki, Shimizu Eri, Ishikawa Junko, Ogi Tomoo, Akiyama Masashi

JOURNAL OF DERMATOLOGICAL SCIENCE   Vol. 97 ( 1 ) page： 50 - 56   2020.1

Homozygous variant p.Ser427Pro in PNPLA1 is a preventive factor from atopic dermatitis

Watanabe Naoki, Kono Michihiro, Suganuma Mutsumi, Tanahashi Kana, Akiyama Masashi

JOURNAL OF DERMATOLOGICAL SCIENCE   Vol. 97 ( 1 ) page： 86 - 88   2020.1

Case of erythrokeratodermia variabilis successfully treated with narrowband ultraviolet B

Okuda Kayoko, Nishida Emi, Tori Kan, Matubara Akihiro, Sagawa Yoko, Takeichi Takuya, Akiyama Masashi, Morita Akimichi

JOURNAL OF DERMATOLOGY   Vol. 47 ( 1 ) page： E30 - E31   2020.1

A case of systemic lupus erythematosus/systemic sclerosis overlap syndrome successfully treated with belimumab.

Hara M, Ogawa-Momohara M, Muro Y, Takeichi T, Akiyama M

European journal of dermatology : EJD   Vol. 30 ( 5 ) page： 615 - 617   2020

Pituitary dysfunction induced by immune checkpoint inhibitors is associated with better overall survival in both malignant melanoma and non-small cell lung carcinoma: a prospective study

Kobayashi Tomoko, Iwama Shintaro, Yasuda Yoshinori, Okada Norio, Okuji Takayuki, Ito Masaaki, Onoue Takeshi, Goto Motomitsu, Sugiyama Mariko, Tsunekawa Taku, Takagi Hiroshi, Hagiwara Daisuke, Ito Yoshihiro, Suga Hidetaka, Banno Ryoichi, Yokota Kenji, Hase Tetsunari, Morise Masahiro, Hashimoto Naozumi, Ando Masahiko, Fujimoto Yasushi, Hibi Hideharu, Sone Michihiko, Ando Yuichi, Akiyama Masashi, Hasegawa Yoshinori, Arima Hiroshi

JOURNAL FOR IMMUNOTHERAPY OF CANCER   Vol. 8 ( 2 )   2020

Oculodentodigital Dysplasia Diagnosed from Severe Hypotrichosis

Taki Tomoki, Takeichi Takuya, Sugiura Kazumitsu, Akiyama Masashi

ACTA DERMATO-VENEREOLOGICA   Vol. 99 ( 13 ) page： 1307 - 1308   2019.12

Response to: 'Anti-Ku antibodies: important points to consider' by Mahler <i>et al</i>.

Ogawa-Momohara M, Muro Y, Akiyama M

Annals of the rheumatic diseases     2019.11

Antiphospholipid antibody-positive Sjogren's syndrome with leg ulcers

Ota Saki, Muro Yoshinao, Kono Michihiro, Goto Naoya, Akiyama Masashi

JOURNAL OF DERMATOLOGY   Vol. 46 ( 11 ) page： E429 - E430   2019.11

Ganciclovir pre-emptive therapy for cytomegalovirus antigenemia in a pemphigus vulgaris patient.

Shibata A, Yoshikawa T, Makita S, Takami N, Matsuzaki T, Sugiyama Y, Akiyama M

The Journal of dermatology   Vol. 46 ( 11 ) page： E423 - E424   2019.11

Successful treatment of pustulotic arthro-osteitis with apremilast: a case report with follow-up MRI

Takama Hiroyuki, Ando Yoriko, Yanagishita Takeshi, Ohshima Yuichiro, Akiyama Masashi, Watanabe Daisuke

EUROPEAN JOURNAL OF DERMATOLOGY   Vol. 29 ( 6 ) page： 656 - 658   2019.11

Japanese real-world study of sequential nivolumab and ipilimumab treament in melanoma.

Tsutsumida A, Fukushima S, Yokota K, Yoshikawa S, Yamasaki O, Tanemura A, Okuyama R, Uhara H, Muto Y, Miyashita A, Akiyama M, Kaji T, Koga H, Kato J, Katayama T, Itakura E, Yamazaki N, Kiyohara Y

The Journal of dermatology   Vol. 46 ( 11 ) page： 947 - 955   2019.11

Overlap of systemic lupus erythematosus and myositis is rare in anti-Ku antibody-positive patients.

Ogawa-Momohara M, Muro Y, Akiyama M

Annals of the rheumatic diseases     2019.10

Case of herpes zoster complicated with paralysis of the recurrent and glossopharyngeal nerves.

Shibata A, Yoshikawa T, Makita S, Ueda Y, Akiyama M

The Journal of dermatology   Vol. 46 ( 10 ) page： E348 - E350   2019.10

Drug-induced acute eosinophilic pneumonia due to hydroxychloroquine in a chilblain lupus patient

Ishiguro Yuri, Muro Yoshinao, Murase Chiaki, Takeichi Takuya, Kono Michihiro, Adachi Runa, Takahashi Kazuomi, Akiyama Masashi

JOURNAL OF DERMATOLOGY   Vol. 46 ( 10 ) page： E356 - E357   2019.10

Clinical characteristics of anti-Ro52 alpha and anti-Ro52 beta antibodies in dermatomyositis/polymyositis

Ogawa-Momohara Mariko, Muro Yoshinao, Mitsuma Teruyuki, Katayama Masao, Yanaba Koichi, Nara Mizuho, Kakeda Masato, Akiyama Masashi

JOURNAL OF DERMATOLOGICAL SCIENCE   Vol. 96 ( 1 ) page： 50 - 52   2019.10

Pityriasis rubra pilaris type V with a heterozygous mutation in CARD14

Miyauchi T., Nomura T., Suzuki S., Takeda M., Peh J., Natsuga K., Fujita Y., Nishie W., Akiyama M., Shimizu H.

JOURNAL OF INVESTIGATIVE DERMATOLOGY   Vol. 139 ( 9 ) page： S265 - S265   2019.9

Hailey-Hailey disease with oesophageal involvement due to a previously unreported ATP2C1 mutation.

Kono M, Kodera M, Inasaka Y, Hasegawa I, Muro Y, Nakazawa Y, Ogi T, Akiyama M

European journal of dermatology : EJD     2019.8

A case of recurrent Stevens-Johnson syndrome caused by nivolumab therapy.

Shibata A, Yoshikawa T, Makita S, Nakagawa S, Ueda Y, Akiyama M

European journal of dermatology : EJD     2019.7

Studies on differentiation-dependent expression and activity of distinct transglutaminases by specific substrate peptides using three-dimensional reconstituted epidermis

Tanabe Yuki, Yamane Miki, Kato Manami, Teshima Hirofumi, Kuribayashi Miki, Tatsukawa Hideki, Takama Hiroyuki, Akiyama Masashi, Hitomi Kiyotaka

FEBS JOURNAL   Vol. 286 ( 13 ) page： 2536 - 2548   2019.7

Acrodermatitis continua of Hallopeau with dense infiltration of IgG4-positive cells in the lesional dermis

Ogawa-Momohara M., Muro Y., Nakaguro M., Takeichi T., Kono M., Akiyama M.

BRITISH JOURNAL OF DERMATOLOGY   Vol. 180 ( 4 ) page： 941 - 942   2019.4

Anti-Mi-2 antibody titers and cutaneous manifestations in dermatomyositis

Ogawa-Momohara Mariko, Muro Yoshinao, Akiyama Masashi

JOURNAL OF CUTANEOUS IMMUNOLOGY AND ALLERGY   Vol. 2 ( 2 ) page： 49-52   2019.4

Congenital ichthyoses: there is always more to learn about managing these rare and complex diseases

Akiyama M.

BRITISH JOURNAL OF DERMATOLOGY   Vol. 180 ( 3 ) page： 449-450   2019.3

Urticarial vasculitis and subcutaneous nodules in the extremities seen in a patient with mucopolysaccharidosis II after hematopoietic stem cell therapy.

Shibata A, Yoshikawa T, Makita S, Takama H, Arakawa T, Akiyama M

The Journal of dermatology   Vol. 46 ( 2 ) page： E63 - E64   2019.2

Somatic recombination underlies frequent revertant mosaicism in loricrin keratoderma.

Suzuki S, Nomura T, Miyauchi T, Takeda M, Fujita Y, Nishie W, Akiyama M, Ishida-Yamamoto A, Shimizu H

Life science alliance   Vol. 2 ( 1 )   2019.2

The lipoxygenase-hepoxilin pathway is activated in cutaneous plaque lesions of psoriasis

Takeichi Takuya, Kinoshita Fumie, Tanaka Hirotaka, Fujita Setsuko, Kobayashi Yumiko, Nakatochi Masahiro, Sugiura Kazumitsu, Akiyama Masashi

JOURNAL OF CUTANEOUS IMMUNOLOGY AND ALLERGY   Vol. 2 ( 1 ) page： 15-24   2019.2

Multiple pebble-like ectopic nails as a subsequent complication of phenol cauterization treatment for onychocryptosis.

Fujita-Tanaka H, Kono M, Sakakibara A, Akiyama M

The Journal of dermatology     2019.1

Unilateral case of multiple minute digitate hyperkeratosis.

Okochi S, Kono M, Takama H, Takeichi T, Muro Y, Akiyama M

The Journal of dermatology     2019.1

A Japanese Case of Galli-Galli Disease due to a Previously Unreported POGLUT1 Mutation.

Kono M, Sawada M, Nakazawa Y, Ogi T, Muro Y, Akiyama M

Acta dermato-venereologica     2019.1

Aberrant CARD14 function might cause defective barrier formation.

Murase Y, Takeichi T, Akiyama M

The Journal of allergy and clinical immunology     2019.1

Dyschromatosis symmetrica hereditaria and reticulate acropigmentation of Kitamura: An update.

Kono M, Akiyama M

Journal of dermatological science     2019.1

Brooke-Spiegler syndrome with chronic obstructive pulmonary disease and chronic sinusitis.

Hattori Y, Takeichi T, Akiyama M, Seishima M

The Journal of dermatology     2019.1

Equestrian cold panniculitis in a cold-storage-room worker.

Adachi A, Masaki S, Akiyama M

The Journal of dermatology     2019.1

Prognosis of dysphagia in dermatomyositis.

Ogawa-Momohara M, Muro Y, Kono M, Akiyama M

Clinical and experimental rheumatology   Vol. 37 ( 1 ) page： 165   2019.1

[Successful treatment of pre-engraftment disseminated fusariosis with high-dose liposomal amphotericin B in a cord blood transplant recipient].

Harada Y, Murata M, Matsumoto A, Kato D, Yagi T, Yaguchi T, Yoshikawa T, Takeichi T, Akiyama M, Yamaguchi Y, Koyama D, Terakura S, Nishida T, Kiyoi H

[Rinsho ketsueki] The Japanese journal of clinical hematology   Vol. 60 ( 12 ) page： 1641 - 1646   2019

Prognosis of dysphagia in dermatomyositis

Ogawa-Momohara M., Muro Y., Kono M., Akiyama M.

CLINICAL AND EXPERIMENTAL RHEUMATOLOGY   Vol. 37 ( 1 ) page： 165 - 165   2019

Indeterminate dendritic cell neoplasm accompanied by eosinophilic pneumonia successfully treated by systemic steroid therapy: Report of the first case with muscular and parotid involvement and review of published work.

Kiyohara T, Nakamaru S, Miyamoto M, Shijimaya T, Nagano N, Makimura K, Takama H, Akiyama M, Tanimura H

The Journal of dermatology   Vol. 45 ( 12 ) page： 1444 - 1447   2018.12

Autosomal dominant progressive hyperpigmentation and lentigines in a Japanese pedigree due to a missense mutation near the C-terminus of KIT

Takeichi T., Sugiura K., Tanahashi K., Noda K., Kono M., Akiyama M.

BRITISH JOURNAL OF DERMATOLOGY   Vol. 179 ( 5 ) page： 1210-1211   2018.11

Cross-sectional survey on disease severity in Japanese patients with harlequin ichthyosis/ichthyosis: Syndromic forms and quality-of-life analysis in a subgroup.

Murase C, Takeichi T, Shibata A, Nakatochi M, Kinoshita F, Kubo A, Nakajima K, Ishii N, Amano H, Masuda K, Kawakami H, Kanekura T, Washio K, Asano M, Teramura K, Akasaka E, Tohyama M, Hatano Y, Ochiai T, Moriwaki S, Sato T, Ishida-Yamamoto A, Seishima M, Kurosawa M, Ikeda S, Akiyama M

Journal of dermatological science   Vol. 92 ( 2 ) page： 127 - 133   2018.11

Japanese guidelines for the management and treatment of generalized pustular psoriasis: The new pathogenesis and treatment of GPP

Fujita Hideki, Terui Tadashi, Hayama Koremasa, Akiyama Masashi, Ikeda Shigaku, Mabuchi Tomotaka, Ozawa Akira, Kanekura Takuro, Kurosawa Michiko, Komine Mayumi, Nakajima Kimiko, Sano Shigetoshi, Nemoto Osamu, Muto Masahiko, Imai Yasutomo, Yamanishi Kiyofumi, Aoyama Yumi, Iwatsuki Keiji

JOURNAL OF DERMATOLOGY   Vol. 45 ( 11 ) page： 1235 - 1270   2018.11

Mild Hailey-Hailey disease cases with aberrant splicing variants of ATP2C1 successfully controlled with excimer light

Kono M., Niizawa M., Takeichi T., Muro Y., Akiyama M.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY   Vol. 32 ( 11 ) page： E413-E416   2018.11

Hearing impairment: A secondary symptom in a congenital ichthyosiform erythroderma patient with ABCA12 mutations

Murase Chiaki, Takeichi Takuya, Sugiura Kazumitsu, Kobayashi Miki, Shiomi Kozue, Ikebuchi Kaichiro, Tsutsumi Yutaka, Akiyama Masashi

JOURNAL OF DERMATOLOGY   Vol. 45 ( 11 ) page： E303-E304   2018.11

Girdin/GIV regulates collective cancer cell migration by controlling cell adhesion and cytoskeletal organization

Wang Xiaoze, Enomoto Atsushi, Weng Liang, Mizutani Yasuyuki, Abudureyimu Shaniya, Esaki Nobutoshi, Tsuyuki Yuta, Chen Chen, Mii Shinji, Asai Naoya, Haga Hisashi, Ishida Sumire, Yokota Kenji, Akiyama Masashi, Takahashi Masahide

CANCER SCIENCE   Vol. 109 ( 11 ) page： 3643-3656   2018.11

Dipeptidyl Peptidase-4 Inhibitor-associated Bullous Pemphigoid: Recurrence with Epitope Spreading

Takama Hiroyuki, Yoshida Makiko, Izumi Kentaro, Yanagishista Takeshi, Muto Jun, Ohshima Yuichiro, Nishie Wataru, Shimizu Hiroshi, Akiyama Masashi, Watanabe Daisuke

ACTA DERMATO-VENEREOLOGICA   Vol. 98 ( 10 ) page： 983-984   2018.11

Strong correlation between cancer progression and anti-transcription intermediary factor 1γ antibodies in dermatomyositis patients.

Ogawa-Momohara M, Muro Y, Mitsuma T, Katayama M, Yanaba K, Nara M, Kakeda M, Kono M, Akiyama M

Clinical and experimental rheumatology   Vol. 36 ( 6 ) page： 990 - 995   2018.11

Dyschromatosis symmetrica hereditaria may be successfully controlled by topical sunscreen.

Kono M, Okamoto T, Takeichi T, Muro Y, Akiyama M

European journal of dermatology : EJD     2018.10

Case of mild X-linked ichthyosis complicated with paroxysmal supraventricular tachycardia and anemia.

Maki Y, Takeichi T, Kono M, Tanaka Y, Akiyama M

The Journal of dermatology   Vol. 45 ( 10 ) page： e275-e276   2018.10

Deficiency of the interleukin-36 receptor antagonist dramatically improved by secukinumab

Kinoshita Manao, Okamoto Takashi, Sano Shinya, Mitsui Hiroshi, Takeichi Takuya, Sugiura Kazumitsu, Akiyama Masashi, Shimada Shinji, Kawamura Tatsuyoshi

JOURNAL OF DERMATOLOGY   Vol. 45 ( 10 ) page： E280-E281   2018.10

Dyschromatosis symmetrica hereditaria with chilblains due to a novel two-amino-acid deletion in the double-stranded RNA-binding domain of ADAR1

Kono M., Suganuma M., Shimada T., Ishikura Y., Watanabe S., Takeichi T., Muro Y., Akiyama M.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY   Vol. 32 ( 10 ) page： E394-E396   2018.10

Familial or sporadic porokeratosis as an autoinflammatory keratinization disease.

Takeichi T, Akiyama M

The Journal of dermatology     2018.9

Increased healthcare costs for filaggrin-related eczema and asthma: hope for targeted management and prevention

Akiyama M., Bray N.

BRITISH JOURNAL OF DERMATOLOGY   Vol. 179 ( 3 ) page： 564-565   2018.9

Hyaline vascular-type unicentric Castleman disease presenting as a subcutaneous nodule in a child.

Hanamura T, Kono M, Yokota K, Takeichi T, Kohno K, Nakamura S, Mitsuma T, Nakajima K, Muro Y, Akiyama M

The Journal of dermatology     2018.8

Roles of aberrant hemichannel activities due to mutant connexin26 in the pathogenesis of KID syndrome

Taki T., Takeichi T., Sugiura K., Akiyama M.

SCIENTIFIC REPORTS   Vol. 8   2018.8

Case of adult-onset Still's disease with psoriasiform eruptions.

Ito Y, Takeichi T, Koide T, Akiyama M

The Journal of dermatology     2018.8

Filaggrin gene mutations may influence the persistence of food allergies in Japanese primary school children

Kono M., Akiyama M., Inoue Y., Nomura T., Hata A., Okamoto Y., Takeichi T., Muro Y., McLean W. H. I., Shimizu H., Sugiura K., Suzuki Y., Shimojo N.

BRITISH JOURNAL OF DERMATOLOGY   Vol. 179 ( 1 ) page： 190-191   2018.7

Mild case of Hailey-Hailey disease caused by a novel ATP2C1 mutation

Hanamura Takuya, Takeichi Takuya, Okuno Yusuke, Ichikawa Daisuke, Kono Michihiro, Akiyama Masashi

JOURNAL OF DERMATOLOGY   Vol. 45 ( 7 ) page： E207-E208   2018.7

The benefits of high-resolution, real-time colour-imaging of lymphatic flow for sentinel lymph node biopsy.

Yokota K, Matsumoto T, Urata T, Goto K, Kono M, Akiyama M

European journal of dermatology : EJD     2018.6

Dyshidrosiform pemphigoid restricted to the soles

Hioki Tomoyuki, Shibata Akitaka, Makita Sumiko, Akiyama Masashi

INTERNATIONAL JOURNAL OF DERMATOLOGY   Vol. 57 ( 6 ) page： 742-743   2018.6

Late-Onset Fulminant Myocarditis With Immune Checkpoint Inhibitor Nivolumab

Yamaguchi Shogo, Morimoto Ryota, Okumura Takahiro, Yamashita Yuta, Haga Tomoaki, Kuwayama Tasuku, Yokoi Tsuyoshi, Hiraiwa Hiroaki, Kondo Toru, Sugiura Yuki, Watanabe Naoki, Kano Naoaki, Kohno Kei, Fukaya Kenji, Sawamura Akinori, Yokota Kenji, Ishii Hideki, Nakaguro Masato, Akiyama Masashi, Murohara Toyoaki

CANADIAN JOURNAL OF CARDIOLOGY   Vol. 34 ( 6 ) page： 812.e1-812.e3   2018.6

Autoinflammatory keratinization diseases: An emerging concept encompassing various inflammatory keratinization disorders of the skin

Akiyama Masashi, Takeichi Takuya, McGrath John A., Sugiura Kazumitsu

JOURNAL OF DERMATOLOGICAL SCIENCE   Vol. 90 ( 2 ) page： 105-111   2018.5

Author's response to the comment to "Compound heterozygotes for filaggrin gene mutations do not always show severe atopic dermatitis'

Sekiya A., Kono M., Akiyama M.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY   Vol. 32 ( 5 ) page： E178-E179   2018.5

Analysis of genotype/phenotype correlations in Japanese patients with dyschromatosis symmetrica hereditaria

Kobayashi Tomoko, Kono Michihiro, Suganuma Mutsumi, Akita Hirotaka, Takai Ayaka, Tsutsui Kiyohiro, Inasaka Yu, Takeichi Takuya, Muro Yoshinao, Akiyama Masashi

NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 80 ( 2 ) page： 267-277   2018.5

An infant with generalized pustular psoriasis and geographic tongue had a heterozygous IL36RN mutation and IgG2 deficiency

Oi Risako, Takeichi Takuya, Okuno Yusuke, Kojima Daiei, Sugawara Kyoko, Kono Michihiro, Muramatsu Hideki, Akiyama Masashi

JOURNAL OF DERMATOLOGICAL SCIENCE   Vol. 90 ( 2 ) page： 216-218   2018.5

Hidradenitis suppurativa as an autoinflammatory keratinization disease Reply

Akiyama Masashi

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY   Vol. 141 ( 5 ) page： 1953 - 1954   2018.5

National survey of quality of life and disease severity in patients with congenital ichthyosis

Murase C., Takeichi T., Shibata A., Nakatochi M., Kinoshita F., Ikeda S., Kurosawa M., Akiyama M.

JOURNAL OF INVESTIGATIVE DERMATOLOGY   Vol. 138 ( 5 ) page： S44 - S44   2018.5

CD1a-positive cutaneous mastocytosis: Electron microscopic evidence of pleomorphic mast cell proliferation

Kiyohara Takahiro, Nagano Naoko, Terai Sayaka, Nakamaru Sei, Makimura Kaoru, Takama Hiroyuki, Akiyama Masashi, Tanimura Hirotsugu

JOURNAL OF DERMATOLOGY   Vol. 45 ( 4 ) page： E86-E87   2018.4

Dermoscopic features of endocrine mucin-producing sweat gland carcinoma

Hasegawa-Murakami Yoshie, Kono Michihiro, Yokota Kenji, Inaba Hiroko, Fukumoto Takaya, Akiyama Masashi

JOURNAL OF DERMATOLOGY   Vol. 45 ( 3 ) page： 353-356   2018.3

Patients With Antithyroid Antibodies Are Prone To Develop Destructive Thyroiditis by Nivolumab: A Prospective Study

Kobayashi Tomoko, Iwama Shintaro, Yasuda Yoshinori, Okada Norio, Tsunekawa Taku, Onoue Takeshi, Takagi Hiroshi, Hagiwara Daisuke, Ito Yoshihiro, Morishita Yoshiaki, Goto Motomitsu, Suga Hidetaka, Banno Ryoichi, Yokota Kenji, Hase Tetsunari, Morise Masahiro, Hashimoto Naozumi, Ando Masahiko, Kiyoi Hitoshi, Gotoh Momokazu, Ando Yuichi, Akiyama Masashi, Hasegawa Yoshinori, Arima Hiroshi

JOURNAL OF THE ENDOCRINE SOCIETY   Vol. 2 ( 3 ) page： 241-251   2018.3

Pansclerotic morphea associated with hypohidrosis and anti-M3 muscarinic acetylcholine receptor antibodies

Fujita-Tanaka H., Ogawa Y., Muro Y., Ogawa-Momohara M., Asashima H., Tsuboi H., Sumida T., Akiyama M.

BRITISH JOURNAL OF DERMATOLOGY   Vol. 178 ( 3 ) page： E210-E211   2018.3

Highly variable clinical feature and course of aggressive digital papillary adenocarcinoma

Yokota Kenji, Kono Michihiro, Shimizu Kazue, Sakakibara Akihiro, Akiyama Masashi

JOURNAL OF DERMATOLOGY   Vol. 45 ( 3 ) page： 357-360   2018.3

A novel IFIH1 mutation in the pincer domain underlies the clinical features of both Aicardi-Goutieres and Singleton-Merten syndromes in a single patient

Takeichi T., Katayama C., Tanaka T., Okuno Y., Murakami N., Kono M., Sugiura K., Aoyama Y., Akiyama M.

BRITISH JOURNAL OF DERMATOLOGY   Vol. 178 ( 2 ) page： E111-E113   2018.2

Trichothiodystrophy, complementation group A complicated with squamous cell carcinoma

Takeichi T., Tomimura S., Okuno Y., Hamada M., Kono M., Sugiura K., Akiyama M.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY   Vol. 32 ( 2 ) page： E75-E77   2018.2

Multiple keratotic papules and plaques on the trunk in Cowden's disease with MALT lymphoma

Mizuno Sayaka, Takeichi Takuya, Sato Junichi, Nakamura Masanao, Goto Hidemi, Sugiura Kazumitsu, Akiyama Masashi

JOURNAL OF DERMATOLOGY   Vol. 45 ( 2 ) page： 238-240   2018.2

Adult Staphylococcal Scalded Skin Syndrome Successfully Treated with Multimodal Therapy Including Intravenous Immunoglobulin

Urata Toru, Kono Michihiro, Ishihara Yuka, Akiyama Masashi

ACTA DERMATO-VENEREOLOGICA   Vol. 98 ( 1 ) page： 136-137   2018.1

Cytomegalovirus reactivation accompanied by varicella zoster virus reactivation or reinfection in an adult patient of multiple myeloma during bortezomib therapy

Hioki Tomoyuki, Takama Hiroyuki, Makita Sumiko, Watanabe Kazuko, Watanabe Daisuke, Akiyama Masashi

JOURNAL OF DERMATOLOGY   Vol. 45 ( 1 ) page： 108-109   2018.1

Hailey-Hailey disease due to ATP2C1 splice site mutation, successfully treated with minocycline hydrochloride

Kono M., Niizawa M., Takeichi T., Muro Y., Akiyama M.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY   Vol. 32 ( 1 ) page： E19-E20   2018.1

Hyper-IgE syndrome with a novel mutation of the STAT3 gene (vol 41, pg 687, 2016)

Minakawa S., Tanaka H., Kaneko T., Matsuzaki Y., Kono M., Akiyama M., Minegishi Y., Sawamura D.

CLINICAL AND EXPERIMENTAL DERMATOLOGY   Vol. 43 ( 1 ) page： 113 - 113   2018.1

Eosinophilia and systemic symptoms with transient ageusia: a drug reaction caused by zonisamide

Adachi Runa, Kono Michihiro, Takeichi Takuya, Muro Yoshinao, Akiyama Masashi

EUROPEAN JOURNAL OF DERMATOLOGY   Vol. 28 ( 4 ) page： 523 - 524   2018

Intramuscular haemorrhage in a patient with dermatomyositis and anti-TIF1 gamma antibodies

Adachi Runa, Muro Yoshinao, Kono Michihiro, Akiyama Masashi

EUROPEAN JOURNAL OF DERMATOLOGY   Vol. 28 ( 1 ) page： 116-118   2018

Impetigo herpetiformis with IL-36RN mutation successfully treated with secukinumab

Kinoshita Manao, Ogawa Youichi, Takeichi Takuya, Okamoto Takashi, Osada Atsushi, Shimada Shinji, Sugiura Kazumitsu, Akiyama Masashi, Kawamura Tatsuyoshi, Tsukamoto Katsuhiko

EUROPEAN JOURNAL OF DERMATOLOGY   Vol. 28 ( 3 ) page： 381 - 382   2018

Granulomatous pigmented purpuric dermatosis containing Propionibacterium acnes

Takama Hiroyuki, Yanagishista Takeshi, Muto Jun, Ohshima Yuichiro, Takahashi Emiko, Tsuzuki Toyonori, Uchida Keisuke, Eishi Yoshinobu, Akiyama Masashi, Watanabe Daisuke

EUROPEAN JOURNAL OF DERMATOLOGY   Vol. 28 ( 4 ) page： 540 - 542   2018

Sunlight is merely a temporary modifier of dyschromatosis symmetrica hereditaria

Kono Michihiro, Miyamura Yoshinori, Tomita Yasushi, Akiyama Masashi

EUROPEAN JOURNAL OF DERMATOLOGY   Vol. 28 ( 2 ) page： 251-252   2018

Superficial epidermolytic ichthyosis concomitant with atopic dermatitis

Shimada Hiromitsu, Takeo Naoko, Saito-Shono Tomoko, Ishikawa Kazushi, Sakai Takashi, Goto Mizuki, Hatano Yutaka, Fujiwara Sakuhei, Matsuda Mitsuhiro, Hamada Takahiro, Nakama Takekuni, Hashimoto Takashi, Kono Michihiro, Akiyama Masashi, Kitajima Yasuo

EUROPEAN JOURNAL OF DERMATOLOGY   Vol. 28 ( 1 ) page： 94 - 96   2018

Strong correlation between cancer progression and anti-transcription intermediary factor 1 gamma antibodies in dermatomyositis patients

Ogawa-Momohara M., Muro Y., Mitsuma T., Katayama M., Yanaba K., Nara M., Kakeda M., Kono M., Akiyama M.

CLINICAL AND EXPERIMENTAL RHEUMATOLOGY   Vol. 36 ( 6 ) page： 990-995   2018

Autoinflammatory keratinization diseases Reviewed

Akiyama M, Takeichi T, McGrath JA, Sugiura K

J Allergy Clin Immunol   Vol. 140 ( 6 ) page： 1545-1547   2017.12

Ultrasonography, a useful tool for detecting tumour "pseudoprogression'

Akiyama M.

BRITISH JOURNAL OF DERMATOLOGY   Vol. 177 ( 6 ) page： 1483-1484   2017.12

Clinicopathological analysis of 46 cases with CD4(+) and/or CD56(+) immature haematolymphoid malignancy: reappraisal of blastic plasmacytoid dendritic cell and related neoplasms

Suzuki Yuka, Kato Seiichi, Kohno Kei, Satou Akira, Eladl Ahmed E., Asano Naoko, Kono Michihiro, Kato Yuichi, Taniwaki Masafumi, Akiyama Masashi, Nakamura Shigeo

HISTOPATHOLOGY   Vol. 71 ( 6 ) page： 972-984   2017.12

Granulocyte and monocyte apheresis can control juvenile generalized pustular psoriasis with mutation of IL36RN

Koike Y., Okubo M., Kiyohara T., Fukuchi R., Sato Y., Kuwatsuka S., Takeichi T., Akiyama M., Sugiura K., Utani A.

BRITISH JOURNAL OF DERMATOLOGY   Vol. 177 ( 6 ) page： 1732-1736   2017.12

Biallelic mutations in KDSR disrupt ceramide synthesis and result in a spectrum of keratinization disorders associated with thrombocytopenia Reviewed

Takeichi T, Torrelo A, Lee JYW, Ohno Y, Lozano ML, Kihara A, Liu L, Yasuda Y, Ishikawa J, Murase T, Rodrigo AB, Fernández-Crehuet P, Toi Y, Mellerio J, Rivera J, Vicente V, Kelsell DP, Nishimura Y, Okuno Y, Kojima D, Ogawa Y, Sugiura K, Simpson MA, McLean WHI, Akiyama M, McGrath JA

J Invest Dermatol   Vol. 137 ( 11 ) page： 2344-2353   2017.11

Eosinophilic annular erythema localized on the neck

Hioki Tomoyuki, Takama Hiroyuki, Makita Sumiko, Shibata Akitaka, Akiyama Masashi, Watanabe Daisuke

EUROPEAN JOURNAL OF DERMATOLOGY   Vol. 27 ( 6 ) page： 673-674   2017.11

Leg ulcers associated with cutaneous vascular degeneration in a patient receiving pazopanib chemotherapy.

Hioki T, Takama H, Makita S, Chen KR, Watanabe D, Akiyama M

European journal of dermatology : EJD   Vol. 27 ( 5 ) page： 546-547   2017.10

Abscopal Effect of Local Irradiation Treatment for Diffuse Large B-cell Lymphoma

Hidaka Yuri, Takeichi Takuya, Ishikawa Yuichi, Kawamura Mariko, Akiyama Masashi

ACTA DERMATO-VENEREOLOGICA   Vol. 97 ( 9 ) page： 1140-1141   2017.10

A combination of low-dose systemic etretinate and topical calcipotriol/betamethasone dipropionate treatment for hyperkeratosis and itching in Olmsted syndrome associated with a TRPV3 mutation

Takeichi Takuya, Tsukamoto Katsuhiko, Okuno Yusuke, Kojima Daiei, Kono Michihiro, Suga Yasushi, Akiyama Masashi

JOURNAL OF DERMATOLOGICAL SCIENCE   Vol. 88 ( 1 ) page： 144-146   2017.10

Corneocyte lipid envelope (CLE), the key structure for skin barrier function and ichthyosis pathogenesis

Akiyama Masashi

JOURNAL OF DERMATOLOGICAL SCIENCE   Vol. 88 ( 1 ) page： 3-9   2017.10

Phosphorylated signal transducer and activator of transcription 3 in the epidermis in adult-onset Still's disease

Takeichi Takuya, Watanabe Naoki, Muro Yoshinao, Teshigawara Shiho, Sato Motoki, Ban Nobutaro, Akiyama Masashi

JOURNAL OF DERMATOLOGY   Vol. 44 ( 10 ) page： 1172-1175   2017.10

Image Gallery: Unilaterally dominant acrokeratoelastoidosis (punctate palmoplantar keratoderma type 3)

Taki T., Ogawa Y., Sakakibara A., Kono M., Akiyama M.

BRITISH JOURNAL OF DERMATOLOGY   Vol. 177 ( 4 ) page： E157-E157   2017.10

A child with epidermolytic ichthyosis from a parent with epidermolytic nevus: risk evaluation of transmission from mosaic to germline Reviewed

Kono M, Suga Y, Akashi T, Ito Y, Takeichi T, Muro Y, Akiyama M

J Invest Dermatol   Vol. 137 ( 9 ) page： 2024-2026   2017.9

Deficient stratum corneum intercellular lipid in a Japanese patient with lamellar ichthyosis with a homozygous deletion mutation in SDR9C7

Takeichi T., Nomura T., Takama H., Kono M., Sugiura K., Watanabe D., Shimizu H., Simpson M. A., McGrath J. A., Akiyama M.

BRITISH JOURNAL OF DERMATOLOGY   Vol. 177 ( 3 ) page： E62-E64   2017.9

Prevalence of anti-NT5C1A antibodies in Japanese patients with autoimmune rheumatic diseases in comparison with other patient cohorts

Muro Yoshinao, Nakanishi Hirotaka, Katsuno Masahisa, Kono Michihiro, Akiyama Masashi

CLINICA CHIMICA ACTA   Vol. 472   page： 1-4   2017.9

Pigmented macules in Waardenburg syndrome type 2 due to KITLG mutation

Ogawa Yasushi, Kono Michihiro, Akiyama Masashi

PIGMENT CELL & MELANOMA RESEARCH   Vol. 30 ( 5 ) page： 501-504   2017.9

Leg ulcers associated with cutaneous vascular degeneration in a patient receiving pazopanib chemotherapy

Hioki Tomoyuki, Takama Hiroyuki, Makita Sumiko, Chen Ko-Ron, Watanabe Daisuke, Akiyama Masashi

EUROPEAN JOURNAL OF DERMATOLOGY   Vol. 27 ( 5 ) page： 546-547   2017.9

Autoantibodies to Su/Argonaute 2 in Japanese patients with inflammatory myopathy

Ogawa-Momohara Mariko, Muro Yoshinao, Satoh Minoru, Akiyama Masashi

CLINICA CHIMICA ACTA   Vol. 471   page： 304-307   2017.8

Corneocyte lipid envelope (CLE), the key structure for skin barrier function and ichthyosis pathogenesis Reviewed

Akiyama M

J Dermatol Sci   Vol. 88 ( 1 ) page： 3-9   2017.7

Infantile bullous pemphigoid successfully treated with intravenous immunoglobulin therapy

Watanabe T., Hara S., Muto J., Watanabe D., Akiyama M.

CLINICAL AND EXPERIMENTAL DERMATOLOGY   Vol. 42 ( 5 ) page： 576-578   2017.7

Certolizumab pegol, a pegylated anti-TNF- antagonist, caused de novo-onset palmoplantar pustulosis followed by generalized pustular psoriasis in a patient with rheumatoid arthritis

Koizumi Haruka, Tokuriki Atsushi, Oyama Noritaka, Ido Hideki, Sugiura Kazumitsu, Akiyama Masashi, Hasegawa Minoru

JOURNAL OF DERMATOLOGY   Vol. 44 ( 6 ) page： 723-724   2017.6

Infant bald patch: ultrasonographic diagnosis of aplasia cutis congenita

Hioki T., Takama H., Makita S., Akiyama M.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY   Vol. 31 ( 6 ) page： E276-E277   2017.6

Anti-dense Fine Speckled 70 Autoantibodies in Japanese Children with Dermatomyositis, Localized Scleroderma, and Idiopathic Arthritis with Iridocyclitis

Muro Yoshinao, Iwata Naomi, Tanaka Yoshihito, Kodera Masanari, Kono Michihiro, Akiyama Masashi

JOURNAL OF RHEUMATOLOGY   Vol. 44 ( 5 ) page： 711-712   2017.5

Image Gallery: Palmoplantar hyperkeratosis in dermatomyositis with anti-PM/Scl antibodies

Taki T., Muro Y., Ogawa Y., Akiyama M.

BRITISH JOURNAL OF DERMATOLOGY   Vol. 176 ( 5 ) page： E94-E94   2017.5

Syndactyly type III and hypotrichosis in oculodentodigital syndrome with GJA1 mutation

Taki T., Takeichi T., Sugiura K., Akiyama M.

JOURNAL OF INVESTIGATIVE DERMATOLOGY   Vol. 137 ( 5 ) page： S151-S151   2017.5

Congenital Ichthyosis and Recurrent Eczema Associated with a Novel ALOXE3 Mutation

Takeichi Takuya, Okuno Yusuke, Saito Chiyo, Kojima Daiei, Kono Michihiro, Morita Akimichi, Sugiura Kazumitsu, Akiyama Masashi

ACTA DERMATO-VENEREOLOGICA   Vol. 97 ( 4 ) page： 532-533   2017.4

Morphological analyses in fragility of pili torti with Bjornstad syndrome

Marubashi Yuki, Yanagishita Takeshi, Muto Jun, Taguchi Nobuhiko, Sugiura Kazumitsu, Kawamoto Yoshiyuki, Akiyama Masashi, Watanabe Daisuke

JOURNAL OF DERMATOLOGY   Vol. 44 ( 4 ) page： 455-458   2017.4

Near-infrared image-guided super-selective intra-arterial infusion of high-dose cisplatin for squamous cell carcinoma on the lower lip

Yokota Kenji, Matsumoto Takaaki, Murakami Yoshie, Akiyama Masashi

EUROPEAN JOURNAL OF DERMATOLOGY   Vol. 27 ( 2 ) page： 208-209   2017.3

Punctate palmoplantar keratoderma type 1 with a novel AAGAB frameshift mutation: intrafamilial phenotype variation due to ageing

Kono M., Fukai K., Shimizu N., Nagao J., Takeichi T., Tsuruta D., Sugiura K., Akiyama M.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY   Vol. 31 ( 3 ) page： E175-E176   2017.3

Pectoral nerve blocks are useful for axillary sentinel lymph node biopsy in malignant tumors on the upper extremities

Yokota Kenji, Matsumoto Takaaki, Murakami Yoshie, Akiyama Masashi

INTERNATIONAL JOURNAL OF DERMATOLOGY   Vol. 56 ( 3 ) page： E64-E65   2017.3

Striate Palmoplantar Keratoderma Showing Transgrediens in a Patient Harbouring Heterozygous Nonsense Mutations in Both DSG1 and SERPINB7

Fukaura Ryo, Takeichi Takuya, Okuno Yusuke, Kojima Daiei, Kono Michihiro, Sugiura Kazumitsu, Suga Yasushi, Akiyama Masashi

ACTA DERMATO-VENEREOLOGICA   Vol. 97 ( 3 ) page： 399-401   2017.3

Successful treatment of a cutaneous ulcer due to cholesterol crystal embolization with topical basic fibroblast growth factor

Takeichi Takuya, Akiyama Masashi

EUROPEAN JOURNAL OF DERMATOLOGY   Vol. 27 ( 2 ) page： 182-183   2017.3

Large intragenic deletion in DSTYK underlies autosomal recessive complicated spastic paraparesis (SPG23) Reviewed

Lee JYW, Hsu C-K, Michael M, Nanda A, Liu L, McMillan JR, Pourreyron C, Takeichi T, Tolar J, Reid E, Hayday T, Blumen SC, Abu-Mouch S, Straussberg R, Basel-Vanagaite L, Barhum Y, Zouabi Y, Al-Ajmi H, Huang H-Y, Lin T-C, Akiyama M, Lee JYY, McLean WHI, Simpson MA, Parsons M, McGrath JA

Am J Hum Genet   Vol. 100 ( 2 ) page： 364-370   2017.2

A case of epidermolytic ichthyosis showing a very mild phenotype due to a novel tail extension mutation in KRT10

Kono M., Fukai K., Omura R., Sugawara K., Tsuruta D., Sugiura K., Akiyama M.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY   Vol. 31 ( 2 ) page： E68-E69   2017.2

Compound heterozygosity for novel splice site mutations of ITGA6 in lethal junctional epidermolysis bullosa with pyloric atresia

Masunaga Takuji, Ogawa Junki, Akiyama Masashi, Nishikawa Takeji, Shimizu Hiroshi, Ishiko Akira

JOURNAL OF DERMATOLOGY   Vol. 44 ( 2 ) page： 160-166   2017.2

Ripple-pattern lichen amyloidosis in a case of ichthyosis vulgaris with a novel FLG mutation

Kono M., Nishida K., Takeichi T., Sugiura K., Akiyama M.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY   Vol. 31 ( 2 ) page： E130-E132   2017.2

Recurrent Cellulitis Caused by Helicobacter cinaedi in a Patient with X-linked Agammaglobulinaemia

Sugimoto Masayo, Takeichi Takuya, Muramatsu Hideki, Kojima Daiei, Osada Yukari, Kono Michihiro, Kojima Seiji, Akiyama Masashi

ACTA DERMATO-VENEREOLOGICA   Vol. 97 ( 2 ) page： 277-278   2017.2

Epstein-Barr Virus-associated Natural Killer/T-cell Lymphoma in a Patient Receiving Therapy with Anti-Tumour Necrosis Factor and Thiopurine

Murase Chiaki, Ogawa Yasushi, Yamamoto Azusa, Iriyama Chisako, Akiyama Masashi

ACTA DERMATO-VENEREOLOGICA   Vol. 97 ( 2 ) page： 273-274   2017.2

Syndromic inherited poikiloderma due to a de novo mutation in FAM111B

Takeichi T., Nanda A., Yang H. -S., Hsu C. -K., Lee J. Y. -Y., Al-Ajmi H., Akiyama M., Simpson M. A., McGrath J. A.

BRITISH JOURNAL OF DERMATOLOGY   Vol. 176 ( 2 ) page： 534-536   2017.2

Anticentromere antibody-positive primary Sjogren's syndrome: Epitope analysis of a subset of anticentromere antibody-positive patients

Tanaka Noriyo, Muro Yoshinao, Suzuki Yasunori, Nishiyama Susumu, Takada Kunio, Sekiguchi Masahiro, Hashimoto Naoaki, Ohmura Koichiro, Shimoyama Kumiko, Saito Ichiro, Kawano Mitsuhiro, Akiyama Masashi

MODERN RHEUMATOLOGY   Vol. 27 ( 1 ) page： 115-121   2017.1

Angiofibroma of Soft Tissue on the Cheek: Diagnosis Confirmed by Gene Rearrangement in NCOA2

Jeong Jin-Wook, Kono Michihiro, Hasegawa-Murakami Yoshie, Motoi Toru, Yokota Kenji, Matsumoto Takaaki, Kaibuchi-Ando Kaori, Kato Yoichi, Tada Toyohiro, Akiyama Masashi

ACTA DERMATO-VENEREOLOGICA   Vol. 97 ( 1 ) page： 133-134   2017.1

A newly revealed IL36RN mutation in sibling cases complements our IL36RN mutation statistics for generalized pustular psoriasis

Takeichi Takuya, Togawa Yaei, Okuno Yusuke, Taniguchi Rieko, Kono Michihiro, Matsue Hiroyuki, Sugiura Kazumitsu, Akiyama Masashi

JOURNAL OF DERMATOLOGICAL SCIENCE   Vol. 85 ( 1 ) page： 58-60   2017.1

Pityriasis rubra pilaris type V as an autoinflammatory disease by CARD14 mutations. Reviewed

Takeichi T, Sugiura K, Nomura T, Sakamoto T, Ogawa Y, Oiso N, Futei Y, Fujisaki A, Koizumi A, Aoyama Y, Nakajima K, Hatano Y, Hayashi K, Ishida-Yamamoto A, Fujiwara, S, Sano S, Iwatsuki K, Kawada A, Suga Y, Shimizu H, McGrath JA, Akiyama M

JAMA Dermatol   Vol. 153 ( 1 ) page： 66-70   2017.1

Compound heterozygotes for filaggrin gene mutations do not always show severe atopic dermatitis

Sekiya A., Kono M., Tsujiuchi H., Kobayashi T., Nomura T., Kitakawa M., Suzuki N., Yamanaka K., Sueki H., McLean W. H. I., Shimizu H., Akiyama M.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY   Vol. 31 ( 1 ) page： 158-162   2017.1