Updated on 2026/01/13

写真a

 
TERAMAE Hiroki
 
Organization
Graduate School of Medicine Program in Integrated Medicine Development Assistant Professor
Graduate School
Graduate School of Medicine
Undergraduate School
School of Medicine Department of Medicine
Title
Assistant Professor

Degree 3

  1. 博士(医学) ( 2010.9   北海道大学 ) 

  2. 修士(医科学) ( 2005.3   北海道大学 ) 

  3. 学士(教育学) ( 2003.3   北海道教育大学 ) 

Research Interests 2

  1. Anatomy

  2. Science Education

Research Areas 1

  1. Life Science / Anatomy

Research History 2

  1. Nagoya University   Assistant Professor

    2025.4

  2. Nagoya Keizai University   Faculty of Human Life and Sciences Department of Health and Nutritional Science   Associate Professor

    2024.4 - 2025.3

Professional Memberships 2

  1. 日本顕微鏡学会

    2024.10

  2. 日本生物教育学会

Committee Memberships 1

  1. 教科「理科」関連学会協議会   委員(日本生物教育学会)  

    2017.9   

 

Papers 20

  1. In vitro proliferation and long-term preservation of functional primary rat hepatocytes in cell fibers Reviewed Open Access

    Mazari-Arrighi E,Okitsu T,Teramae H,Aoyagi H,Kiyosawa M,Yano M,Chatelain F,Fuchs A,Takeuchi S

    Scientific reports   Vol. 12 ( 1 )   2022.5

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    Language:English  

    DOI: 10.1038/s41598-022-12679-3

    Open Access

  2. Millimeter-thick xenoislet-laden fibers as retrievable transplants mitigate foreign body reactions for long-term glycemic control in diabetic mice Reviewed

    Watanabe T,Okitsu T,Ozawa F,Nagata S,Matsunari H,Nagashima H,Nagaya M,Teramae H,Takeuchi S

    Biomaterials   Vol. 255   2020.10

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    Language:English  

    DOI: 10.1016/j.biomaterials.2020.120162

  3. Recombinant collagenase from Grimontia hollisae as a tissue dissociation enzyme for isolating primary cells Reviewed Open Access

    Tanaka K,Okitsu T,Teramura N,Iijima K,Hayashida O,Teramae H,Hattori S

    Scientific reports   Vol. 10 ( 1 )   2020.3

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    Language:English  

    DOI: 10.1038/s41598-020-60802-z

    Open Access

  4. Hyperglycaemia augments lipopolysaccharide-induced reduction in rat and human macrophage phagocytosis via the endoplasmic stress-C/EBP homologous protein pathway Reviewed

    Iida J,Ishii S,Nakajima Y,Sessler DI,Teramae H,Kageyama K,Maeda S,Anada N,Shibasaki M,Sawa T,Nakayama Y

    British journal of anaesthesia   Vol. 123 ( 1 ) page: 51 - 59   2019.7

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    Language:English  

    DOI: 10.1016/j.bja.2019.03.040

  5. 3D tissue formation of unilocular adipocytes in hydrogel microfibers Reviewed

    Hsiao AY,Okitsu T,Teramae H,Takeuchi S

    Advanced healthcare materials   Vol. 5 ( 5 ) page: 548 - 556   2016.3

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    Language:English  

    DOI: 10.1002/adhm.201500673

  6. Smooth muscle-like tissue constructs with circumferentially oriented cells formed by the cell fiber technology Reviewed Open Access

    Hsiao AY,Okitsu T,Onoe H,Kiyosawa M,Teramae H,Iwanaga S,Kazama T,Matsumoto T,Takeuchi S

    PloS one   Vol. 10 ( 3 ) page: e0119010   2015.3

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  7. Cellular building unit integrated with microstrand-shaped bacterial cellulose Reviewed

    Hirayama K,Okitsu T,Teramae H,Kiriya D,Onoe H,Takeuchi S

    Biomaterials   Vol. 34 ( 10 ) page: 2421 - 2427   2013.5

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    Language:English  

    DOI: 10.1016/j.biomaterials.2012.12.013

  8. Hypoxia affects in vitro growth of newly established cell lines from patients with malignant pleural mesothelioma Reviewed Open Access

    Goudarzi H,Hida Y,Takano H,Teramae H,Iizasa H,Hamada J

    Biomedical research (Tokyo, Japan)   Vol. 34 ( 1 ) page: 13 - 21   2013.2

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    Language:English  

    DOI: 10.2220/biomedres.34.13

    Open Access

  9. Improved hypothermic short-term storage of isolated mouse islets by adding serum to preservation solutions Reviewed Open Access

    Kimura Y,Okitsu T,Xibao L,Teramae H,Okonogi A,Toyoda K,Uemoto S,Fukushima M

    Islets   Vol. 5 ( 1 ) page: 45 - 52   2013.1

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    Language:Japanese  

    DOI: 10.4161/isl.24025

    Open Access

  10. ENDOPLASMIC RETICULUM STRESS SENSOR PROTEINS EXPRESSION AND ITS ALTERATION IN SEPSIS DEPEND ON CELL TYPES IN PANCREAS AND ADRENAL GLAND

    Suzuki, T; Matsuda, N; Teramae, H; Sato, N; Koike, K

    SHOCK   Vol. 37   page: 111 - 111   2012

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  11. Augmented damage of islets by impaired exocrine acinar cells undergoing apoptosis that is possibly converted to necrosis during isolation Reviewed Open Access

    Elgendy H,Okitsu T,Kimura Y,Liu X,Nafady-Hego H,Kurata J,Teramae H,Elbahrawy A,Uemoto S,Fukuda K

    Islets   Vol. 3 ( 3 ) page: 102 - 110   2011.5

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    Language:English  

    DOI: 10.4161/isl.3.3.15611

  12. FADD SIRNA REDUCES AUTOPHAGY AND APOPTOSIS IN SEPTIC MICE

    Matsuda, N; Teramae, H

    CRITICAL CARE MEDICINE   Vol. 38 ( 12 ) page: U20 - U20   2010.12

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  13. The cellular expression of SMCT2 and its comparison with other transporters for monocarboxylates in the mouse digestive tract Reviewed Open Access

    Teramae H,Yoshikawa T,Inoue R,Ushida K,Takebe K,Nio-Kobayashi J,Iwanaga T

    Biomedical research (Tokyo, Japan)   Vol. 31 ( 4 ) page: 239 - 249   2010.8

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    Language:English  

    DOI: 10.2220/biomedres.31.239

    Open Access

  14. The modulation of vascular ATP-sensitive K+ channel function via the phosphatidylinositol 3-kinase-Akt pathway activated by phenylephrine Reviewed

    Haba M,Hatakeyama N,Kinoshita H,Teramae H,Azma T,Hatano Y,Matsuda N

    The journal of pharmacology and experimental therapeutics   Vol. 334 ( 2 ) page: 673 - 678   2010.8

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  15. Up-regulation of histamine H4 receptors contributes to splenic apoptosis in septic mice: counteraction of the antiapoptotic action of nuclear factor-kappaB Reviewed

    Matsuda N,Teramae H,Futatsugi M,Takano K,Yamamoto S,Tomita K,Suzuki T,Yokoo H,Koike K,Hattori Y

    The journal of pharmacology and experimental therapeutics   Vol. 332 ( 3 ) page: 730 - 737   2010.5

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    Language:English  

    DOI: 10.1124/jpet.109.163543

  16. Insights Into Sepsis Therapeutic Design Based on the Apoptotic Death Pathway Open Access

    Hattori Yuichi, Takano Ken-ichi, Teramae Hiroki, Yamamoto Seiji, Yokoo Hiroki, Matsuda Naoyuki

    Journal of Pharmacological Sciences   Vol. 114 ( 4 ) page: 354 - 365   2010

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    Language:English   Publisher:The Japanese Pharmacological Society  

    Sepsis remains the leading cause of death in critically ill patients. A major problem contributing to sepsis-related high mortality is the lack of effective medical treatment. Thus, the key goal in critical care medicine is to develop novel therapeutic strategies that will impact favorably on septic patient outcome. While it is generally accepted that sepsis is an inflammatory state resulting from the systemic response to infection, apoptosis is implicated to be an important mechanism of the death of lymphocytes, gastrointestinal and lung epithelial cells, and vascular endothelial cells associated with the development of multiple organ failure in sepsis. The pivotal role of cell apoptosis is now highlighted by multiple studies demonstrating that prevention of cell apoptosis can improve survival in clinically relevant animal models of sepsis. In this review article, we address the scientific rationale for remedying apoptotic cell death in sepsis and propose that therapeutic efforts aimed at blocking cell signaling pathways leading to apoptosis may represent an attractive target for sepsis therapy.

    DOI: 10.1254/jphs.10r04cr

    Web of Science

    Scopus

    PubMed

    CiNii Research

  17. Systemic Inflammatory Response Syndrome (SIRS) and Tachyarrhythmia: How to Construct Treatment Strategy?

    HATAKEYAMA Noboru, AOKI Yuta, KINOSHITA Hiroyuki, TERAMAE Hiroki, MATSUDA Naoyuki, YAMAZAKI Mitsuaki

    THE JOURNAL OF JAPAN SOCIETY FOR CLINICAL ANESTHESIA   Vol. 30 ( 5 ) page: 765 - 770   2010

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    Language:Japanese   Publisher:THE JAPAN SOCIETY FOR CLINICAL ANESTHESIA  

    Tachyarrhythmia is frequently seen during the course of SIRS and it is sometimes intractable. Sympathetic hypertonia and hyper catecholaminea, in addition to inhibited expression of L-type calcium channel and over-expression of active nitrogen species, account for the pathogenesis of tachyarrhythmia. Combined use of a phosphodiesterase III inhibitor and a β blocker is recommended to construct a treatment strategy.

    DOI: 10.2199/jjsca.30.765

    CiNii Research

  18. A novel approach to prevent progressive apoptosis in septic shock Reviewed

    Matsuda N,Yamamoto S,Teramae H,Takano KI,Beppu S,Yamazaki H,Yokoo H,Hatakeyama N,Koike K,Hattori Y

    Nihon yakurigaku zasshi. Folia pharmacologica Japonica   Vol. 134 ( 4 ) page: 198 - 201   2009

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    Language:Japanese  

    DOI: 10.1254/fpj.134.198

  19. Cellular expression of Noc2, a Rab effector protein, in endocrine and exocrine tissues in the mouse Reviewed

    Teramae H,Fujimoto W,Seino S,Iwanaga T

    Histochemistry and cell biology   Vol. 127 ( 1 )   2007.1

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    Authorship:Lead author   Language:English  

    DOI: 10.1007/s00418-006-0207-0

  20. Electronic structure of polycarbosilane studied by UV photoelectron spectroscopy

    Sakurai, Y; Yoshimura, D; Ishii, H; Ouchi, Y; Isaka, H; Teramae, H; Matsumoto, N; Hasegawa, S; Ueno, N; Seki, K

    JOURNAL OF PHYSICAL CHEMISTRY B   Vol. 105 ( 24 ) page: 5626 - 5629   2001.6

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    Publisher:Journal of Physical Chemistry B  

    An ultraviolet photoelectron spectroscopic study was performed to examine the electronic structure of poly(1,1,2,2-tetramethyldisilylenemethylene), [(SiMe<inf>2</inf>)<inf>2</inf>CH<inf>2</inf>]<inf>n</inf>, which consists of repeating Si-Si-C units. We compared the observed spectra to reported gas-phase spectra of Si<inf>2</inf>Me<inf>6</inf> and Si<inf>4</inf>Me<inf>10</inf> and theoretical molecular orbital calculations. Theoretical calculations by the ab initio and PM3 methods agree well with the observed spectra, which enabled assignment of the observed spectral features. The broad peak derived from Si-Si bond orbitals in polycarbosilane suggests that Si-Si units, which are separated by carbon atoms, still interact with each other, to form σ-conjugation through the backbone. The observed ionization threshold energy of the polycarbosilane[(SiMe<inf>2</inf>)<inf>2</inf>CH<inf>2</inf>]<inf>n</inf> is 6.4 eV. The dispersion of the highest valence band of polycarbosilane is less than that of polysilane, indicating that the degree of σ-conjugation of polycarbosilane is smaller than that of polysilane.

    DOI: 10.1021/jp0031698

    Web of Science

    Scopus

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KAKENHI (Grants-in-Aid for Scientific Research) 3

  1. Development and evaluation of usefulness of objective structured practice examination in teacher training stage

    Grant number:16K13585  2016.4 - 2019.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Challenging Exploratory Research

    TERAMAE Hiroki

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    In teacher training, in addition to teaching skills and curriculum development, students who wish to be science teachers for secondary schools and students who are interested in primary teachers are required to master skills of science experiments. Also in the recruitment screening exams for public school teachers, there are local governments that impose practical exams of science experiments and observations, so the applicants must obtain such skills as teachers.
    In this study, we developed the Objective Structured Practical Examination (OSPE) for students in the teacher training stage. In particular, in elementary and junior high school, we worked on the evaluation of experimental skill tests for microscopes used in all grades, and verified the validity of test items and evaluation methods from trial tests. As a result, it became clear that the variation of scoring by evaluators was small, and the usefulness as an experimental skill test was suggested.

  2. Functional morphology analysis of an autophagy and Gene therapy on the pancreatic B cell in an inflammation stimulus

    Grant number:26861530  2014.4 - 2016.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Young Scientists (B)

    TERAMAE Hiroki

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    Severe sepsis is easy to combine systemic inflammation by pro inflammatory cytokines production but an effective remedy hasn't been established yet.
    In this study, I cultured pancreatic B cell line Min6, provided inflammation stimulus on it and examined how the autophagy effects mRNAs, proteins and morphology in this cell line.
    Together these results, I will analyze those of the cells knocked down autophagy derived protein and summarized this monograph.

  3. 炎症刺激下での血管内皮細胞における蛋白異化の形態的ならびに分子生物学的解明

    Grant number:23792073  2011.4 - 2012.3

    日本学術振興会  科学研究費助成事業  若手研究(B)

    寺前 洋生

 

Teaching Experience (On-campus) 1

  1. 現代医学入門

    2025

Teaching Experience (Off-campus) 9

  1. 生化学Ⅱ

    2025.9 Nagoya Keizai University)

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    Level:Undergraduate (specialized)  Country:Japan

  2. 生化学実験Ⅱ

    2025.9 Nagoya Keizai University)

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    Level:Undergraduate (specialized)  Country:Japan

  3. 運動生理学

    2024.9 Nagoya Keizai University)

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    Level:Undergraduate (specialized)  Country:Japan

  4. 生化学実験Ⅰ

    2024.4 Nagoya Keizai University)

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    Level:Undergraduate (specialized)  Country:Japan

  5. 生化学Ⅰ

    2024.4 Nagoya Keizai University)

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    Level:Undergraduate (specialized)  Country:Japan

  6. 生化学

    2023.9 Taisei Gakuin University)

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    Country:Japan

  7. 解剖生理学Ⅱ

    2023.9 Taisei Gakuin University)

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    Level:Undergraduate (specialized)  Country:Japan

  8. 解剖生理学Ⅰ

    2023.4 Taisei Gakuin University)

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    Level:Undergraduate (specialized)  Country:Japan

  9. 生物学

    2023.4 Taisei Gakuin University)

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    Level:Undergraduate (specialized)  Country:Japan

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