Publishing type：Research paper (scientific journal)   Publisher：Beilstein Institut  

Lithium ion-endohedral fullerene (Li⁺@C₆₀), a member of the burgeoning family of ion-endohedral fullerenes, holds substantial promise for diverse applications owing to its distinctive ionic properties. Despite the high demand for precise property tuning through chemical modification, there have been only a few reports detailing synthetic protocols for the derivatization of this novel material. In this study, we report the synthesis of Li⁺@C₆₀ derivatives via the thermal [2 + 2] cycloaddition reaction of styrene derivatives, achieving significantly higher yields of monofunctionalized Li⁺@C₆₀ compared to previously reported reactions. Furthermore, by combining experimental and theoretical approaches, we clarified the range of applicable substrates for the thermal [2 + 2] cycloaddition of Li⁺@C₆₀, highlighting the expanded scope of this straightforward and selective functionalization method.

DOI： 10.3762/bjoc.20.58

Other Link： https://www.beilstein-journals.org/bjoc/content/pdf/1860-5397-20-58.pdf