Organization
Nagoya University Hospital Obstetrics and Gynecology Assistant Professor
Graduate School
Graduate School of Medicine
Title
Assistant Professor
NAGAO Yukari
Degree 1
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博士（医学） （ 2024.9 名古屋大学 ）
Awards 4
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名古屋大学学術奨励賞
2024.5 名古屋大学
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日本産科婦人科学会優秀論文賞
2024.3 日本産科婦人科学会
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名古屋大学医学系研究科医学奨励賞
2023.12 名古屋大学
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日本癌学会若手研究者ポスター賞
2021.10 日本癌学会
Papers 13
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Natural-killer-cell-dominant immune landscape and HLA-E-mediated immune evasion in choriocarcinoma Reviewed Open Access
Shibata, M; Yoshida, K; Yasui, Y; Nishiko, Y; Hattori, S; Nakamura, K; Koya, Y; Yamamoto, Y; Suzuki, K; Yoshihara, M; Nagao, Y; Tamauchi, S; Yokoi, A; Yoshikawa, N; Nishino, K; Yamamoto, E; Niimi, K; Kajiyama, H
PLACENTA Vol. 174 page： 9 - 18 2026.2
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Risk factors for recurrent cases of early-stage uterine sarcoma after complete surgical resection Reviewed Open Access
Nagao, Y; Yokoi, A; Yoshida, K; Yoshihara, M; Tamauchi, S; Yoshikawa, N; Niimi, K; Kajiyama, H
BMC CANCER Vol. 26 ( 1 ) 2026.1
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Downregulation of Chromosome 19 miRNA Cluster and the Tumor-Suppressive Role of miR-517a-3p in Choriocarcinoma Reviewed Open Access
Nishiko, Y; Yoshida, K; Yasui, Y; Yokoi, A; Kitagawa, M; Inami, E; Yoshihara, M; Mogi, K; Nagao, Y; Tamauchi, S; Yoshikawa, N; Nishino, K; Yamamoto, E; Niimi, K; Kajiyama, H
CANCER SCIENCE Vol. 116 ( 12 ) page： 3473 - 3486 2025.12
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Exploring drug resistance via intercellular crosstalk using spatial transcriptomics in high-grade serous ovarian carcinoma Reviewed Open Access
Suzuki, H; Yoshida, K; Yokoi, A; Suzuki, K; Hirano, Y; Kitagawa, M; Asano-Inami, E; Yoshihara, M; Nagao, Y; Tamauchi, S; Yoshikawa, N; Kajiyama, H; Yamamoto, Y
NPJ PRECISION ONCOLOGY Vol. 9 ( 1 ) page： 345 2025.11
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Application of multimodal integration to develop preoperative diagnostic models for borderline and malignant ovarian tumors Reviewed Open Access
Kunishima, A; Inaba, D; Iyoshi, S; Ikeda, Y; Goto, M; Muramatsu, R; Hashimoto, M; Yoshida, K; Mogi, K; Yoshihara, M; Nagao, Y; Tamauchi, S; Yokoi, A; Yoshikawa, N; Niimi, K; Koizumi, N; Kajiyama, H
SCIENTIFIC REPORTS Vol. 15 ( 1 ) page： 37114 2025.10
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Proteomic Profiling of Bacterial Extracellular Vesicles for Exploring Ovarian Cancer Biomarkers Reviewed Open Access
Asano-Inami, E; Yokoi, A; Yoshida, K; Taki, K; Kitagawa, M; Suzuki, K; Uekusa, R; Nagao, Y; Yoshikawa, N; Niimi, K; Yamamoto, Y; Kajiyama, H
JOURNAL OF EXTRACELLULAR BIOLOGY Vol. 4 ( 10 ) page： e70073 2025.10
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Tamauchi, S; Niimi, K; Iyoshi, S; Yoshida, K; Mogi, K; Yoshihara, M; Nagao, Y; Yokoi, A; Yoshikawa, N; Kajiyama, H
JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH Vol. 51 ( 7 ) page： e70013 2025.7
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子宮平滑筋肉腫における発がんメカニズム解析と新規治療戦略の同定 Open Access
長尾 有佳里, 横井 暁, 吉田 康将, 北川 雅美, 山本 雄介, 加藤 友康, 梶山 広明
日本婦人科腫瘍学会雑誌 Vol. 42 ( 2 ) page： 75 - 85 2024.4
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Nagao, Y; Yokoi, A; Yoshida, K; Kitagawa, M; Asano-Inami, E; Kato, T; Ishikawa, M; Yamamoto, Y; Kajiyama, H
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE Vol. 1870 ( 4 ) page： 167103 2024.4
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Spatial exosome analysis using cellulose nanofiber sheets reveals the location heterogeneity of extracellular vesicles Reviewed
NATURE COMMUNICATIONS Vol. 14 ( 1 ) page： 6915 2023.11
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Small Extracellular Vesicles from adipose-derived stem cells suppress cell proliferation by delivering the let-7 family of microRNAs in ovarian cancer Reviewed
Hironori Suzuki, Akira Yokoi, Kaname Uno, Kosuke Yoshida, Masami Kitagawa, Eri Asano-Inami, Seiko Matsuo, Yukari Nagao, Kazuhiro Suzuki, Kae Nakamura, Masato Yoshihara, Satoshi Tamauchi, Yusuke Shimizu, Yoshiki Ikeda, Nobuhisa Yoshikawa, Hiroaki Kajiyama, Yusuke Yamamoto
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Vol. 680 page： 211 - 219 2023.11
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Novel therapeutic strategies targeting UCP2 in uterine leiomyosarcoma Reviewed
Yukari Nagao, Akira Yokoi, Kosuke Yoshida, Mai Sugiyama, Eri Watanabe, Kae Nakamura, Masami Kitagawa, Eri Asano-Inami, Yoshihiro Koya, Masato Yoshihara, Satoshi Tamauchi, Yusuke Shimizu, Yoshiki Ikeda, Nobuhisa Yoshikawa, Tomoyasu Kato, Yusuke Yamamoto, Hiroaki Kajiyama
PHARMACOLOGICAL RESEARCH Vol. 189 page： 106693 2023.3
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Clinical effects of cervical conization with positive margins in cervical cancer Reviewed
Yukari Nagao, Akira Yokoi, Kosuke Yoshida, Masanori Sumi, Masato Yoshihara, Satoshi Tamauchi, Yoshiki Ikeda, Nobuhisa Yoshikawa, Kimihiro Nishino, Kaoru Niimi, Hiroaki Kajiyama
SCIENTIFIC REPORTS Vol. 11 ( 1 ) page： 23288 2021.12
Research Project for Joint Research, Competitive Funding, etc. 2
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EVシートによる革新的卵巣がん細胞外小胞解析と臨床応用
2025年度JCA-KFCR若手研究助成
Authorship：Principal investigator
Grant amount：\1000000
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EVシートによる卵巣癌患者細胞外小胞バイオマーカー確立
医学研究助成
Grant amount：\500000
KAKENHI (Grants-in-Aid for Scientific Research) 1
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Grant number：25K23841 2025.7 - 2027.3
科学研究費助成事業 研究活動スタート支援
長尾 有佳里
Authorship：Principal investigator
Grant amount：\2730000 （ Direct Cost: \2100000 、 Indirect Cost：\630000 ）
細胞外小胞（Extracellular vesicle、EV）は細胞由来情報を搭載し体液中を循環し機能する。近年我々は微量体液からのEV捕捉と安定的保存を可能とした次世代EV回収法であるEVシートを開発した。EVシートを体液に浸すソーキング法と術中に腹腔内各臓器に貼付するアタッチング法の2種の利用法があり、回収したEVの解析が可能である。本研究では、EVシートの利点を最大限に生かし、卵巣癌の早期診断、病期分類、治療効果予測、再発予測などのバイオマーカーを確立し、卵巣癌の悪性化メカニズムに関わる卵管采由来EVの生物学的特徴や転移巣へのEVの関与を解明する。
Industrial property rights 1
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卵巣癌を検査する方法