Updated on 2024/11/08

写真a

 
AKIYAMA Koichi
 
Organization
Graduate School of Medicine Program in Integrated Medicine Development Professor
Graduate School
Graduate School of Medicine
Undergraduate School
School of Medicine Department of Medicine
Title
Professor
External link

Degree 2

  1. Doctor of Medicine （ 2005.3   Kyoto Prefectural University of Medicine ） 

  2. Doctor of Philosophy （ 2018.3   Kyoto Prefectural University of Medicine ） 

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Research Interests 6

  1. Pseudomons Aeruginosa

  2. Blood Flow Dynamics Analysis

  3. 4D Flow MRI

  4. Intraventricular Pressure Difference

  5. Vector Flow Mapping

  6. echocardiography

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Research Areas 5

  1. Life Science / Anesthesiology  / Anesthesiology

  2. Life Science / Cardiology  / echocardiography

  3. Life Science / Cardiovascular surgery  / cardiovascular surgery

  4. Manufacturing Technology (Mechanical Engineering, Electrical and Electronic Engineering, Chemical Engineering) / Fluid engineering  / Fluid Dynamics

  5. Life Science / Bacteriology  / Pseudomonas Aeruginosa

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Research History 2

  1. Nagoya University Graduate School of Medicine   Department of Anesthesiology   Professor

    2024.10

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  2. Kinki University   Department of Anesthesiology   Lecturer

    2022.6 - 2024.9

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    Country：Japan

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Education 1

  1. Kyoto Prefectural University of Medicine

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    Country： Japan

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Professional Memberships 7

  1. International Anesthesia Research Society

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  2. International Society for Heart and Lung Transplantation

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  3. 日本小児循環器学会

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  4. 日本小児麻酔学会

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  5. 日本心臓血管麻酔学会

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  6. 日本集中治療医学会

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  7. 日本麻酔科学会

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Committee Memberships 4

  1. 日本心筋保護研究会   心筋保護ガイドライン合同研究班委員  

    2023.1   

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    Committee type：Other

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  2. Japanese Society of Cardiovascular Anesthesia   Director  

    2022.6   

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    Committee type：Academic society

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  3. Japanese Society of Cardiovascular Anesthesia   Director of the Academic committee of Transesophageal Echocardiography  

    2022.1   

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    Committee type：Academic society

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  4. Japanese Society of Cardiovascular Anesthesia   Japanese Board of Perioperative Transesophageal Echocardiography Examination Preparation Committee  

    2020.1   

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    Committee type：Academic society

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Papers 94

  1. Variational Mode Decomposition Analysis of Electroencephalograms during General Anesthesia: Using the Grey Wolf Optimizer to Determine Hyperparameters

    Kosuke Kushimoto, Yurie Obata, Tomomi Yamada, Mao Kinoshita, Koichi Akiyama, Teiji Sawa

    Sensors   Vol. 24 ( 17 ) page： 5749 - 5749   2024.9

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    Publishing type：Research paper (scientific journal)   Publisher：MDPI AG  

    Frequency analysis via electroencephalography (EEG) during general anesthesia is used to develop techniques for measuring anesthesia depth. Variational mode decomposition (VMD) enables mathematical optimization methods to decompose EEG signals into natural number intrinsic mode functions with distinct narrow bands. However, the analysis requires the a priori determination of hyperparameters, including the decomposition number (K) and the penalty factor (PF). In the VMD analysis of EEGs derived from a noninterventional and noninvasive retrospective observational study, we adapted the grey wolf optimizer (GWO) to determine the K and PF hyperparameters of the VMD. As a metric for optimization, we calculated the envelope function of the IMF decomposed via the VMD method and used its envelope entropy as the fitness function. The K and PF values varied in each epoch, with one epoch being the analytical unit of EEG; however, the fitness values showed convergence at an early stage in the GWO algorithm. The K value was set to 2 to capture the α wave enhancement observed during the maintenance phase of general anesthesia in intrinsic mode function 2 (IMF-2). This study suggests that using the GWO to optimize VMD hyperparameters enables the construction of a robust analytical model for examining the EEG frequency characteristics involved in the effects of general anesthesia.

    DOI： 10.3390/s24175749

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  2. Pulmonary vein stump thrombosis and organ infarction after lung lobectomy.

    Teiji Sawa, Pipat Saeyup, Mao Kinoshita, Atsushi Kainuma, Satoru Ogawa, Fumimasa Amaya, Koichi Akiyama

    Journal of anesthesia     2024.8

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    Language：English   Publishing type：Research paper (scientific journal)  

    Lung resection surgery, which is performed as a treatment for lung cancer and metastatic lung tumors, is currently conducted via minimally invasive techniques such as video-assisted thoracoscopic surgery and robot-assisted methods. Postoperative complications related to this surgery, such as pulmonary vein thrombosis and cerebral and other organ infarctions, have been increasingly reported. The primary cause of these complications is thrombus formation in the pulmonary vein stump. Statistical data on the site of lung lobectomy have indicated that surgeries involving the left upper lobe are most frequently associated with embolic complications. Although this issue has not received considerable attention in anesthesiology, the importance of prevention and treatment in postoperative management is growing. The role of anesthesiologists in preventing these complications is critical. These roles involve careful fluid management to avoid hypercoagulable states, consideration of early postoperative anticoagulation therapy, assessment of the suitability of epidural anesthesia for postoperative anticoagulation, and improvement of hospital-wide safety systems and monitoring of high-risk patients. Anesthesiologists need to understand the pathology and risk factors involved and play an active role in preventing and treating these complications through effective collaboration with thoracic surgeons and the in-hospital stroke team.

    DOI： 10.1007/s00540-024-03389-3

    PubMed

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  3. Heat‐related changes in the velocity and kinetic energy of flowing blood influence the human heart's output during hyperthermia Reviewed

    Kazuhito Watanabe, Nuno Koch Esteves, Oliver R. Gibson, Koichi Akiyama, Sumie Watanabe, José González‐Alonso

    The Journal of Physiology     2024.5

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Wiley  

    Abstract

    Passive whole‐body hyperthermia increases limb blood flow and cardiac output (), but the interplay between peripheral and central thermo‐haemodynamic mechanisms remains unclear. Here we tested the hypothesis that local hyperthermia‐induced alterations in peripheral blood flow and blood kinetic energy modulate flow to the heart and . Body temperatures, regional (leg, arm, head) and systemic haemodynamics, and left ventricular (LV) volumes and functions were assessed in eight healthy males during: (1) 3 h control (normothermic condition); (2) 3 h of single‐leg heating; (3) 3 h of two‐leg heating; and (4) 2.5 h of whole‐body heating. Leg, forearm, and extracranial blood flow increased in close association with local rises in temperature while brain perfusion remained unchanged. Increases in blood velocity with small to no changes in the conduit artery diameter underpinned the augmented limb and extracranial perfusion. In all heating conditions, increased in association with proportional elevations in systemic vascular conductance, related to enhanced blood flow, blood velocity, vascular conductance and kinetic energy in the limbs and head (all R<sup>2</sup> ≥ 0.803; P &lt; 0.001), but not in the brain. LV systolic (end‐systolic elastance and twist) and diastolic functional profiles (untwisting rate), pulmonary ventilation and systemic aerobic metabolism were only altered in whole‐body heating. These findings substantiate the idea that local hyperthermia‐induced selective alterations in peripheral blood flow modulate the magnitude of flow to the heart and through changes in blood velocity and kinetic energy. Localised heat‐activated events in the peripheral circulation therefore affect the human heart's output.imageKey points

    Local and whole‐body hyperthermia increases limb and systemic perfusion, but the underlying peripheral and central heat‐sensitive mechanisms are not fully established.

    Here we investigated the regional (leg, arm and head) and systemic haemodynamics (cardiac output: ) during passive single‐leg, two‐leg and whole‐body hyperthermia to determine the contribution of peripheral and central thermosensitive factors in the control of human circulation.

    Single‐leg, two‐leg, and whole‐body hyperthermia induced graded increases in leg blood flow and . Brain blood flow, however, remained unchanged in all conditions. Ventilation, extracranial blood flow and cardiac systolic and diastolic functions only increased during whole‐body hyperthermia.

    The augmented with hyperthermia was tightly related to increased limb and head blood velocity, flow and kinetic energy.

    The findings indicate that local thermosensitive mechanisms modulate regional blood velocity, flow and kinetic energy, thereby controlling the magnitude of flow to the heart and thus the coupling of peripheral and central circulation during hyperthermia.

    DOI： 10.1113/jp285760

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  4. Patch dehiscence after mitral valve repair by posterior mitral leaflet augmentation at weaning from cardiopulmonary bypass Reviewed

    Satoshi Aihara, Yoshinobu Nakayama, Yasufumi Nakajima, Takatoshi Tsujimoto, Koichi Akiyama

    Cureus   Vol. 16 ( 6 ) page： e62872   2024

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    Authorship：Last author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： doi: 10.7759/cureus.62872.

  5. Blood flow kinetic energy is a novel marker for right ventricular global systolic function in patients with left ventricular assist device therapy Reviewed International coauthorship

    Koichi Akiyama, Paolo C. Colombo, Eric J. Stöhr, Ruiping Ji, Isaac Y. Wu, Keiichi Itatani, Shohei Miyazaki, Teruyasu Nishino, Naotoshi Nakamura, Yasufumi Nakajima, Barry J McDonnell, Koji Takeda, Melana Yuzefpolskaya, Hiroo Takayama

    Frontiers in Cardiovascular Medicine   Vol. 10   page： 1093576 - 1093576   2023.5

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    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： https://doi.org/10.3389/fcvm.2023.1093576

  6. Time-trend analysis of the center frequency of the intrinsic mode function from the Hilbert–Huang transform of electroencephalography during general anesthesia: a retrospective observational study Reviewed

    Yurie Obata, Tomomi Yamada, Koichi Akiyama, Teiji Sawa

    BMC Anesthesiology   Vol. 23 ( 1 ) page： 125 - 125   2023.4

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1186/s12871-023-02082-4

  7. Loss of left ventricular vortex ring in left ventricular assist device-induced right ventricular failure Reviewed International coauthorship

    Koichi Akiyama, Isaac Wu, Keiichi Itatani, Yosuke Tachibana, Yurie Obata, Hiroo Takayama

    Annals of Cardiac Anaesthesia   Vol. 26 ( 2 ) page： 235 - 235   2023.4

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    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： https://doi.org/10.4103/aca.aca_288_20

  8. Transesophageal echocardiographic diagnosis of pulmonary artery catheter entrapment caused by left atrial suture. Reviewed International coauthorship

    Tachibana Y, Wu I, Obata Y, Shiozaki K, Kawamoto T, Sato S, Inoue K, Azami T, Akiyama K

    Annals of Cardiac Anaesthesia   Vol. 26 ( 1 ) page： 111 - 112   2023

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    Authorship：Last author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： doi: 10.4103/aca.aca_11_21.

  9. PAPVRの患者に対するDouble Decker法による根治術前後の4D flow MRI解析 Reviewed

    秋山浩一、坂本 悠篤, 北條 絵理, 小角 怜子, 鎌本 洋通, 中嶋 康文

      Vol. 27   page： 184 - 184   2023

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    Authorship：Lead author,　Corresponding author   Language：Japanese   Publishing type：Research paper (other academic)  

  10. Pulsatility and flow patterns across macro- and microcirculatory arteries of continuous-flow left ventricular assist device patients Reviewed International coauthorship

    Eric J. Stöhr, Ruiping Ji, Giulio Mondellini, Lorenzo Braghieri, Koichi Akiyama, Francesco Castagna, Alberto Pinsino, John R. Cockcrof, Ronald H. Silverman, Samuel Trocio, Oksana Zatvarska, Elisa Konofagou, Iason Apostolakis, Veli K. Topkara, Hiroo Takayama, Koji Takeda, Yoshifumi Naka, Nir Uriel, Melana Yuzefpolskaya, Joshua Z. Willey, Barry J. McDonnell, Paolo C. Colombo

    Journal of Heart and Lung Transplantation   Vol. 42 ( 9 ) page： 1223 - 1232   2023

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： doi: 10.1016/j.healun.2023.04.002.

  11. Exploring surgical indication of re-RVOTR for patients with Tetralogy of Fallot using 4D flow MR Reviewed

    Koichi Akiyama, Hirokazu Koto, Hiroatsu Sakamoto, Reiko Kosumi, Tomoyuki Matsumoto, Yasufumi Nakajima

    Anesthesia & Analgesia   Vol. 136 ( 5S ) page： 126 - 127   2023

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    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (other academic)  

  12. Development of EEG Mode Decompositor: Hilbert Spectrum Analysis of Electroencephalography During General Anesthesia by Modified Empirical Wavelet Transform Reviewed

    Teiji Sawa, Kazuki Sudo, Tomomi Yamada, Yurie Obata, Koichi Akiyama

    Anesthesia & Analgesia   Vol. 136 ( 5S ) page： 564 - 566   2023

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    Authorship：Last author   Language：English   Publishing type：Research paper (other academic)  

    DOI： https://doi.org/10.1213/01.ane.0000977652.27377.97

  13. 閉塞性肥大型心筋症患者の左室流出路心筋切除前後における,心室内圧較差(IVPD)の変化 Reviewed

    坂本 悠篤, 岡本 健, 法里 慧, 石崎 智哉子, 冬田 昌樹, 岩元 辰篤, 太田 典之, 中嶋 康文, 秋山 浩一

    日本集中治療医学会雑誌   Vol. 30   page： 754 - 754   2023

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    Authorship：Last author,　Corresponding author   Language：Japanese   Publishing type：Research paper (other academic)  

  14. 開心術中に誘引なくRCAが解離した症例 Reviewed

    東方 謙介, 秋山 浩一, 坂本 悠篤, 北條 絵理, 小角 怜子, 中嶋 康文

      Vol. 27   page： 270 - 270   2023

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    Language：Japanese   Publishing type：Research paper (other academic)  

  15. 急性A型大動脈解離の麻酔導入中に左冠動脈にmalperfusionを引き起こし心停止した症例 Reviewed

    北條 絵理, 東方 謙介, 小角 怜子, 坂本 悠篤, 秋山 浩一, 中嶋 康文

      Vol. 27   page： 252 - 252   2023

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    Language：Japanese   Publishing type：Research paper (other academic)  

  16. MICSで脱血管挿入に難渋し、後腹膜血腫をきたした一症例 Reviewed

    鎌本 洋通, 北山 智哉子, 坂本 悠篤, 法里 慧, 北浦 淳寛, 秋山 浩一, 中嶋 康文

      Vol. 27   page： 247 - 247   2023

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  17. 孤立性の僧帽弁前尖cleftに伴う僧帽弁閉鎖不全症の一例 Reviewed

    坂本 悠篤, 秋山 浩一, 北條 絵理, 北浦 淳寛, 中嶋 康文

      Vol. 27   page： 239 - 239   2023

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  18. ST segment elevation immediately after cardiopulmonary bypass during modified Blalock-Taussig shunt and pulmonary artery banding Reviewed International coauthorship

    Koichi Akiyama, Isaac Y. Wu, Kei Hori, Hiroatsu Sakamoto, Reiko Kosumi, Hirokazu Koto, Satoshi Asada, Yasufumi Nakajima

    Journal of Cardiothoracic and Vascular Anesthesia   Vol. 37 ( 9 ) page： 1833 - 1834   2023

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    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： https://doi.org/10.1053/j.jvca.2023.05.034

  19. Preoperative Left Ventricular Energy Loss in the Operating Theater Reflects Subjective Symptoms in Chronic Aortic Regurgitation Reviewed International coauthorship

    Atsushi Kainuma, Keiichi Itatani, Koichi Akiyama, Yoshifumi Naito, Maki Ishii, Masaru Shimizu, Junya Ohara, Naotoshi Nakamura, Yasufumi Nakajima, Satoshi Numata, Hitoshi Yaku, Teiji Sawa

    Frontiers in Surgery   Vol. 9   page： 739743 - 739743   2022.2

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.3389/fsurg.2022.739743

  20. Left Ventricular Assist Device Support-Induced Alteration of Mechanical Stress on Aortic Valve and Aortic Wall Reviewed International coauthorship

    Atsushi Kainuma, Keiichi Itatani, Hideyuki Hayashi, Yuji Kaku, Isaac Y. Wu, Paolo C. Colombo, Giovanni Ferrari, Paul Kurlansky, Melana Yuzefpolskaya, Koji Takeda, Yoshifumi Naka, Koichi Akiyama, Hiroo Takayama

    ASAIO Journal   Vol. 68 ( 4 ) page： 516 - 523   2022

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1097/mat.0000000000001522

  21. Correlation Between Aortic Valve Protein Levels and Vector Flow Mapping Of Wall Shear Stress And Oscillatory Shear Index in Patients Supported with Continuous-Flow Left Ventricular Assist Devices Reviewed International coauthorship

    Serge Kobsa, Koichi Akiyama, Samantha K. Nemeth, Paul A. Kurlansky, Yoshifumi Naka, Koji Takeda, Keiichi Itatani, Emily G. Werth, Lewis M. Brown, Giovanni Ferrari, Hiroo Takayama

    The Journal of Heart and Lung Transplantation   Vol. 42 ( 1 ) page： 64 - 75   2022

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： https://doi.org/10.1016/j.healun.2022.09.017

  22. Paravalvular Leak After Mitral Valve Replacement or Another Source for a Regurgitant Jet? Reviewed International coauthorship

    Yu Hirase, Yurie Obata, Isaac Y. Wu, Hitoshi Sato, Tomoya Sato, Keiichi Itatani, Teiji Sawa, Koichi Akiyama

    Journal of Cardiothoracic and Vascular Anesthesia   Vol. 36 ( 6 ) page： 1807 - 1809   2022

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    Authorship：Last author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： https://doi.org/10.1053/j.jvca.2021.11.037

  23. Recovery of left ventricular diastolic function after cardiopulmonary bypass Reviewed

    Yurie Obata, Koichi Akiyama

    Anesthesia & Analgesia   Vol. 134 ( 5S ) page： 125 - 125   2022

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    Authorship：Last author   Language：English   Publishing type：Research paper (other academic)  

  24. Perioperative fluid dynamic assessment for a patient with aortic and pulmonary regurgitation 20 years after the Ross-Konno procedure Reviewed

    Risa Kawaguchi, Yurie Obata, Yu Hirase, Tomoya Sato, Hirokazu Muneishi, Hitoshi Sato, Teiji Sawa, Koichi Akiyama

    Anesthesia & Analgesia   Vol. 134 ( 5S ) page： 123 - 123   2022

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    Authorship：Last author,　Corresponding author   Language：English   Publishing type：Research paper (other academic)  

  25. Diastolic retrograde flow and wall shear stress in the proximal descending aorta Reviewed

    Koichi Akiyama, Yurie Obata, Yu Hirase, Hitoshi Sato, Tomoya Sato, Teiji Sawa

    Anesthesia & Analgesia   Vol. 134 ( 5S ) page： 102 - 102   2022

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    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (other academic)  

  26. Influence of aneurysmal aortic root geometry on mechanical stress to the aortic valve leaflet Reviewed International coauthorship

    Hideyuki Hayashi, Keiichi Itatani, Koichi Akiyama, Yanling Zhao, Paul Kurlansky, Scott DeRoo, Joseph Sanchez, Giovanni Ferrari, Melana Yuzefpolskaya, Paolo C. Colombo, Koji Takeda, Isaac Y Wu, Atsushi Kainuma, Hiroo Takayama

    European Heart Journal - Cardiovascular Imaging   Vol. 22 ( 9 ) page： 986 - 994   2021.8

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1093/ehjci/jeab006

  27. Difficult Airway Management in Neonates and Infants: Knowledge of Devices and a Device-Oriented Strategy Reviewed

    Teiji Sawa, Atsushi Kainuma, Koichi Akiyama, Mao Kinoshita, Masayuki Shibasaki

    Frontiers in Pediatrics   Vol. 9   page： 654291   2021.5

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.3389/fped.2021.654291

  28. Poincaré Plot Area of Gamma-Band EEG as a Measure of Emergence From Inhalational General Anesthesia Reviewed

    Kazuma Hayase, Atsushi Kainuma, Koichi Akiyama, Mao Kinoshita, Masayuki Shibasaki, Teiji Sawa

    Frontiers in Physiology   Vol. 12   page： 627088   2021.2

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.3389/fphys.2021.627088

  29. Poincaré Plot Area of Gamma-Band EEG as a Measure of Emergence From Inhalational General Anesthesia Reviewed

    Kazuma Hayase, Atsushi Kainuma, Koichi Akiyama, Mao Kinoshita, Masayuki Shibasaki, Teiji Sawa

    Frontiers in Physiology   Vol. 12   page： 627088 - 627088   2021.2

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    DOI： https://doi.org/10.3389/fphys.2021.627088

  30. 4D flow MRI analysis improved perioperative management in a patient with severe pulmonary regurgitation and pulmonary artery aneurysm Reviewed

    Koichi Akiyama, Yurie Obata, Yu Hirase, Teiji Sawa

    Anesthesia & Analgesia   Vol. 132 ( 5S ) page： 171   2021

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    Language：English   Publishing type：Research paper (other academic)  

  31. Cerebral vasoreactivity in HeartMate 3 patients Reviewed International coauthorship

    Eric J. Stöhr, Ruiping Ji, Koichi Akiyama, Giulio Mondellini, Lorenzo Braghieri, Alberto Pinsino, John R. Cockcroft, Melana Yuzefpolskaya, Amrin Amlani, Veli K. Topkara, Hiroo Takayama, Yoshifumi Naka, Nir Uriel, Koji Takeda, Paolo C. Colombo, Barry J. McDonnell, Joshua Z. Willey

    The Journal of Heart and Lung Transplantation   Vol. 40 ( 8 ) page： 786 - 793   2021

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/j.healun.2021.05.005

  32. Difference in Intraventricular Vortex Between the Single Right Ventricle and Single Left Ventricle Reviewed International coauthorship

    Koichi Akiyama, Keiichi Itatani, Isaac Y Wu, Yosuke Tachibana, Yurie Obata, Yasufumi Nakajima, Masaaki Yamagishi, Hiroo Takayama, Teiji Sawa

    Journal of Cardiothoracic and Vascular Anesthesia   Vol. 35 ( 7 ) page： 2242 - 2243   2021

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    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1053/j.jvca.2020.11.008

  33. Intraoperative Diagnosis of a Stuck Bioprosthetic Valve Leaflet Due to a Loop of Suture After Mitral Valve Replacement Reviewed

    Jun Takeshita, Koichi Akiyama, Natsuki Anada, Yasufumi Nakajima

    Journal of Cardiothoracic and Vascular Anesthesia   Vol. 35 ( 6 ) page： 1830 - 1832   2021

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1053/j.jvca.2020.07.007

  34. Assessment of left ventricular diastolic function by analyzing intraventricular pressure difference during third trimester of pregnancy Reviewed

    Yurie Obata, Koichi Akiyama, Yu Hirase, Teiji Sawa

    Anesthesia & Analgesia   Vol. 132 ( 5S ) page： 613   2021

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  35. 4D flow MRI analysis improved perioperative management in a patient with severe pulmonary regurgitation and pulmonary artery aneurysm Reviewed

    Koichi Akiyama, Yurie Obata, Yu Hirase, Teiji Sawa

    Anesthesia & Analgesia   Vol. 132 ( 5S ) page： 613   2021

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    Authorship：Lead author   Language：English   Publishing type：Research paper (other academic)  

  36. 新しい臨床モニタリング 心エコー新時代へ：Vector Flow MappingとIntraventricular Pressure Difference. Invited Reviewed

    秋山浩一

    Anet   Vol. 25 ( 2 ) page： 17 - 24   2021

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    Authorship：Lead author,　Corresponding author   Language：Japanese   Publishing type：Research paper (scientific journal)  

  37. 幽門側胃切除後に肝梗塞を発症した1症例 Reviewed

    春田愛, 林大, 前川真基, 三原聡仁, 秋山浩一

    麻酔   Vol. 70 ( 1 ) page： 94 - 97   2021

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    Authorship：Last author,　Corresponding author   Language：Japanese   Publishing type：Research paper (scientific journal)  

  38. Vector Flow Mappingを用いた大動脈弁のWall Shear Stress解析 Invited Reviewed

    小畑友里江, 秋山浩一

      Vol. 25 ( 1 ) page： 161 - 162   2021

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  39. Epidemiological survey of serum titers from adults against various Gram-negative bacterial V-antigens Reviewed

    Mao Kinoshita, Masaru Shimizu, Koichi Akiyama, Hideya Kato, Kiyoshi Moriyama, Teiji Sawa

    PLOS ONE   Vol. 15 ( 3 ) page： e0220924   2020.3

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： https://doi.org/10.1371/journal.pone.0220924

  40. Energetic performance index improvement after Glenn and Damus-Kaye-Stansel procedure using vector flow mapping analysis: a case report Reviewed

    Atsushi Kainuma, Koichi Akiyama, Yoshifumi Naito, Kazuma Hayase, Hisayuki Hongu, Keiichi Itatani, Masaaki Yamagishi, Teiji Sawa

    JA Clinical Reports   Vol. 6 ( 1 ) page： 5   2020

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： https://doi.org/10.1186/s40981-020-0312-4

  41. A novel in vivo assessment of fluid dynamics on aortic valve leaflet using epi‐aortic echocardiogram Reviewed International coauthorship

    Hideyuki Hayashi, Koichi Akiyama, Keiichi Itatani, Scott DeRoo, Joseph Sanchez, Giovanni Ferrari, Paolo C. Colombo, Koji Takeda, Isaac Y. Wu, Atsushi Kainuma, Hiroo Takayama

    Echocardiography   Vol. 37 ( 2 ) page： 323 - 330   2020

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： https://doi.org/10.1111/echo.14596

  42. Improved metabolic vasoreactivity in the brain of HM3 patients and its underlying microcirculatory mechanisms Reviewed

    Eric J. Stöhr, Ruiping Ji, Koichi Akiyama, Francesco Castagna, Pinsino Alberto, John Cockcroft, Melana Yuzefpolskaya, Reshad Garan, Veli Topkara, Hiroo Takayama, Koji Takeda, Yoshifumi Naka, Paolo Colombo, Joshua Willey, Barry J. McDonnell

    Artery Research   Vol. 25 ( 1S ) page： 142 - 143   2020

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    Language：English   Publishing type：Research paper (other academic)  

    DOI： 10.2991/artres.k.191224.129

  43. Secondary in-hospital epidemiological investigation after an outbreak of Pseudomonas aeruginosa ST357 Reviewed

    Toshihito Mihara, Takeshi Kimura, Kyoko Momiyama, Atsushi Kainuma, Koichi Akiyama, Junya Ohara, Keita Inoue, Mao Kinoshita, Masaru Shimizu, Kiyoshi Moriyama, Naohisa Fujita, Teiji Sawa

    Journal of Infection and Chemotherapy   Vol. 26 ( 3 ) page： 257 - 265   2020

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： https://doi.org/10.1016/j.jiac.2019.09.014

  44. Assessment of Cerebrovascular Reserve in the Heart Failure Patients Supported with the HeartMate3 Reviewed International coauthorship

    R. Ji, E.J. Stohr, K. Akiyama, A. Amlani, G.M. Mondellini, F. Castagna, A. Pinsino, J.R. Cockcroft, M. Yuzefpolskaya, V.K. Topkara, H. Takayama, K. Takeda, Y. Naka, N. Uriel, P.C. Colombo, B. McDonnell, J.Z. Willey

    The Journal of Heart and Lung Transplantation   Vol. 39 ( 4S ) page： 97   2020

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    Language：English   Publishing type：Research paper (other academic)  

  45. HM3 patients do not have an increased pulsatility in large, muscular or microcirculatory arteries Reviewed International coauthorship

    E.J. Stöhr, R. Ji, K. Akiyama, F. Castagna, A. Pinsino, J.R. Cockcroft, N. Uriel, M. Yuzefpolskaya, R. Garan, V. Topkara, H. Takayama, K. Takeda, Y. Naka, W.Z. Joshua, B. McDonnell, P.C. Colombo

    The Journal of Heart and Lung Transplantation   Vol. 39 ( 4S ) page： 138   2020

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    Language：English   Publishing type：Research paper (other academic)  

    DOI： 10.1016/j.healun.2020.01.1051

  46. Wall Shear Stress analysis on aortic valve within aneurysmal aortic root Reviewed International coauthorship

    Koichi Akiyama, Hideyuki Hayashi, Mao Kinoshita, Toshihito Mihara, Mana Haruta, Masaki Maekawa, Dai Hayashi, Teiji Sawa, Hiroo Takayama

    Anesthesia & Analgesia   Vol. 130 ( 5S ) page： 167   2020

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    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (other academic)  

  47. Clonality analysis of clinical isolates of Pseudomonas aeruginosa: The outbreak of high-risk clone ST357 Reviewed

    Toshihito Mihara, Atsushi Kainuma, Koichi Akiyama, Junya Ohara, Keita Inoue, Mao Kinoshita, Masaru Shimizu, Teiji Sawa

    Anesthesia & Analgesia   Vol. 130 ( 5S ) page： 361   2020

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    Language：English   Publishing type：Research paper (other academic)  

  48. V antigen epidemiological survey of pathogenic gram negative bacteria Reviewed

    Mao Kinoshita, Koichi Akiyama, Junya Ohara, Toshihito Mihara, Keita Inoue, Masaru Shimizu, Hideya Kato, Teiji Sawa

    Anesthesia & Analgesia   Vol. 130 ( 5S ) page： 363   2020

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    Language：English   Publishing type：Research paper (other academic)  

  49. Dehydration reduces stroke volume and cardiac output during exercise because of impaired cardiac filling and venous return, not left ventricular function Reviewed International coauthorship

    Kazuhito Watanabe, Eric J. Stöhr, Koichi Akiyama, Sumie Watanabe, José González‐Alonso

    Physiological Reports   Vol. 8 ( 11 ) page： e14433   2020

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： https://doi.org/10.14814/phy2.14433

  50. Preoperative left ventricular energy loss in the operating theater reflects subjective symptoms in patients with chronic aortic regurgitation Reviewed

    Atsushi Kainuma, Koichi Akiyama, Yoshifumi Naito, Mao Kinoshita, Masaru Shimizu, Maki Ishii, Junya Ohara, Teiji Sawa

    Anesthesia & Analgesia   Vol. 128 ( 5S ) page： 949   2019

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    Language：English   Publishing type：Research paper (other academic)  

  51. Novel approach to assess intraventricular pressure difference in patients with left ventricular assist device during ramp study Reviewed International coauthorship

    K. Akiyama, E.J. Stöhr, R. Ji, O.G. Jimenez, I. Wu, K. Itatani, S. Miyazaki, T. Furusawa, T. Nishino, B.J. McDonnell, A.R. Garan, M. Yuzefpolskaya, P.C. Colombo, Y. Naka, H. Takayama, K. Takeda

    The Journal of Heart and Lung Transplantation   Vol. 38 ( 4S ) page： 127 - 128   2019

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    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (other academic)  

  52. A comparison of middle cerebral artery and central retinal artery hemodynamics in HMⅡpatients Reviewed International coauthorship

    E.J. Stöhr, R. Ji, K. Akiyama, F. Castagna, A. Pinsino, J.R. Cockcroft, M. Yuzefpolskaya, A.R. Garan, V.K. Topkara, R.T. Te-Frey, H. Takayama, K. Takeda, Y. Naka, P.C. Colombo, J.Z. Willey, B.J. McDonnell

    The Journal of Heart and Lung Transplantation   Vol. 38 ( 4S ) page： 91   2019

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    Language：English   Publishing type：Research paper (other academic)  

  53. Wall shear stress in the middle cerebral artery of HMⅡpatients – A prospective, mechanistic study using vector flow mapping Reviewed

    K. Akiyama, R. Ji, F. Castagna, A. Pinsino, J.R. Cockcroft, M. Yuzefpolskaya, A.R. Garan, V.K. Topkara, K. Ross, H. Takayama, K. Takeda, Y. Naka, B.J. McDonnell, P.C. Colombo, J.Z. Willey, E.J. Stöhr

    The Journal of Heart and Lung Transplantation   Vol. 38 ( 4S ) page： 424   2019

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    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (other academic)  

  54. Blood flow kinetic energy of right ventricular outflow tract: A marker for right ventricular global systolic function Reviewed International coauthorship

    K. Akiyama, P.C. Colombo, E.J. Stöhr, R. Ji, O.G. Jimenez, I. Wu, S. Shames, K. Itatani, S. Miyazaki, T. Furusawa, T. Nishino, B.J. McDonnell, A.R. Garan, Y. Naka, K. Takeda, H. Takayama, M. Yuzefpolskaya

    The Journal of Heart and Lung Transplantation   Vol. 38 ( 4S ) page： 450   2019

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    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (other academic)  

  55. Assessment of wall shear stress on the aortic valve in patients with left ventricular assist device using vector flow mapping Reviewed International coauthorship

    K. Akiyama, R. Ji, E.J. Stöhr, O.G. Jimenez, I. Wu, K. Itatani, S. Miyazaki, T. Furusawa, T. Nishino, B.J. McDonnell, A.R. Garan, M. Yuzefpolskaya, P.C. Colombo, Y. Naka, K. Takeda, H. Takayama

    The Journal of Heart and Lung Transplantation   Vol. 38 ( 4S ) page： 452   2019

    　More details

    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (other academic)  

  56. Metabolic vasoreactivity in the middle cerebral artery of heart failure patients with and without continuous-flow left ventricular support Reviewed International coauthorship

    R. Ji, K. Akiyama, F. Castagna, A. Pinsino, J.R. Cockcroft, M. Yuzefpolskaya, A. Garan, V.K. Topkara, M.T. Pineda, H. Takayama, K. Takeda, Y. Naka, P.C. Colombo, B. McDonnell, E.J. Stöhr, J.Z. Willey

    The Journal of Heart and Lung Transplantation   Vol. 38 ( 4S ) page： 234   2019

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    Language：English   Publishing type：Research paper (other academic)  

  57. Intraventricular Pressure Difference assessment from color M-mode image using transesophageal echocardiography Reviewed International coauthorship

    Koichi Akiyama, Isaac Wu, Eric J Stöhr, Aaron Mittel, Ruiping Ji, Keiichi Itatani, Yasufumi Nakajima, Atsushi Kainuma, Teiji Sawa, Hiroo Takayama

    Anesthesia & Analgesia   Vol. 128 ( 5S ) page： 144   2019

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    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (other academic)  

  58. Kinetic energy and energy loss in the Middle Cerebral Artery (MCA) of HeartMateⅡpatients Reviewed

    Koichi Akiyama, Ruiping Ji, Autumn Clemons, Francesco Castagna, Alberto Pinsino, John R. Cockcroft, Melana Yuzefpolsakaya, Reshad Garan, Hiroo Takayama, Koji Takeda, Yoshifumi Naka, Veli Topkara, Joshua Willey, Barry J. McDonnell, Paolo Colombo, Eric Stöhr

    Artery Research   Vol. 24 ( C ) page： 104 - 105   2018

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    Authorship：Lead author   Language：English   Publishing type：Research paper (other academic)  

    DOI： https://doi.org/10.1016/j.artres.2018.10.143

  59. 心臓血管内の血流解析とその応用 Invited Reviewed

    秋山浩一

      Vol. 22 ( 1 ) page： 1 - 10   2018

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    Authorship：Lead author,　Corresponding author   Language：Japanese   Publishing type：Research paper (scientific journal)  

  60. The effect of aortic regurgitation jet directionality on energy loss Reviewed

    Koichi Akiyama, Isaac Wu, Atsushi Kainuma, Yasufumi Nakajima, Teiji Sawa, Keiichi Itatani, Hiroo Takayama

    Anesthesia & Analgesia   Vol. 126 ( 4S ) page： 72   2018

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    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (other academic)  

  61. Energetic performance index improvement after Glenn and Damus-Kaye-Stansel procedure using vector flow mapping analysis Reviewed

    Atsushi Kainuma, Kazuma Hayase, Koichi Akiyama, Yoshifumi Naito, Masaru Shimizu, Keiichi Itatani, Teiji Sawa

    Anesthesia & Analgesia   Vol. 126 ( 4S ) page： 61   2018

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  62. An outbreak of fluoroquinolone-resistant Pseudomonas aeruginosa ST357 harboring the exoU gene Reviewed

    Atsushi Kainuma, Kyoko Momiyama, Takeshi Kimura, Koichi Akiyama, Keita Inoue, Yoshifumi Naito, Mao Kinoshita, Masaru Shimizu, Hideya Kato, Nobuaki Shime, Naohisa Fujita, Teiji Sawa

    Journal of Infection and Chemotherapy   Vol. 24 ( 8 ) page： 615 - 622   2018

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： https://doi.org/10.1016/j.jiac.2018.03.008

  63. 経食道心エコーによるIntraventricular Pressure Differenceの解析 Reviewed International coauthorship

    秋山 浩一, 高山 博夫, ウー・アイザック, 内藤 慶文, 中嶋 康文, 佐和 貞治

      Vol. 22   page： 252   2018

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    Authorship：Lead author,　Corresponding author   Language：Japanese   Publishing type：Research paper (other academic)  

  64. Vector flow mapping analysis of left ventricular energetic performance in healthy adult volunteers Reviewed

    Koichi Akiyama, Sachiko Maeda, Tasuku Matsuyama, Atsushi Kainuma, Maki Ishii, Yoshifumi Naito, Mao Kinoshita, Saeko Hamaoka, Hideya Kato, Yasufumi Nakajima, Naotoshi Nakamura, Keiichi Itatani, Teiji Sawa

    BMC Cardiovascular Disorders   Vol. 17 ( 1 ) page： 21   2017

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    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： https://doi.org/10.1186/s12872-016-0444-7

  65. Flow visualization technologyとその実用方法 Reviewed

    秋山 浩一, 石井 真紀, 甲斐沼 篤, 中嶋 康文, 溝部 俊樹, 佐和 貞治

    Cardiovascular Anesthesia   Vol. 21   page： 163   2017

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    Authorship：Lead author,　Corresponding author   Language：Japanese   Publishing type：Research paper (other academic)  

  66. Effective evaluation of arterial pulse waveform analysis by two-dimensional stroke volume variation–stroke volume index plots Reviewed

    Teiji Sawa, Mao Kinoshita, Atsushi Kainuma, Koichi Akiyama, Yoshifumi Naito, Hideya Kato, Fumimasa Amaya, Keiji Shigemi

    Journal of Clinical Monitoring and Computing   Vol. 31 ( 5 ) page： 927 - 941   2017

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： https://doi.org/10.1007/s10877-016-9916-7

  67. 従来型カフ圧計と新しいシリンジ型カフ圧計AG Cuffillの精度比較 Reviewed

    早瀬一馬, 河合直史, 木下真央, 秋山浩一, 坂東瑞樹, 横田勲, 柴﨑雅志

    麻酔   Vol. 66 ( 10 ) page： 1108 - 1112   2017

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    Language：Japanese   Publishing type：Research paper (scientific journal)  

  68. Visualization of suppressed intraventricular flow by constrictive pericarditis Reviewed

    Koichi Akiyama, Keiichi Itatani, Ayahiro Yamashita, Teiji Sawa

    Journal of Clinical Anesthesia   Vol. 42   page： 40 - 41   2017

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    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： https://doi.org/10.1016/j.jclinane.2017.08.013

  69. Energetic performance analysis of staged palliative surgery in tricuspid atresia using vector flow mapping Reviewed

    Mao Kinoshita, Koichi Akiyama, Keiichi Itatani, Ayahiro Yamashita, Maki Ishii, Atsushi Kainuma, Yoshinobu Maeda, Takako Miyazaki, Masaaki Yamagishi, Teiji Sawa

    Cardiovascular Ultrasound   Vol. 15 ( 1 ) page： 27   2017

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    Authorship：Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： https://doi.org/10.1186/s12947-017-0118-3

  70. Flow Energy Loss Evaluation in a Systolic Anterior Motion Case After the Ross Procedure Reviewed

    Koichi Akiyama, Yoshifumi Naito, Mao Kinoshita, Maki Ishii, Yasufumi Nakajima, Keiichi Itatani, Takako Miyazaki, Masaaki Yamagishi, Hitoshi Yaku, Teiji Sawa

    Journal of Cardiothoracic and Vascular Anesthesia   Vol. 31 ( 6 ) page： 2118 - 2122   2017

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    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： https://doi.org/10.1053/j.jvca.2017.03.006

  71. 術中経食道心エコーにて後尖のSystolic Anterior Motionを診断した症例でのenergetic performance analysis Reviewed

    石川 大基, 秋山 浩一, 井上 敬太, 吉田 敬之, 中嶋 康文, 佐和 貞治

    Cardiovascular Anesthesia   Vol. 21   page： 302   2017

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    Language：Japanese   Publishing type：Research paper (other academic)  

  72. Efficacy comparison of adjuvants in PcrV vaccine againstPseudomonas aeruginosapneumonia Reviewed

    Saeko Hamaoka, Yoshifumi Naito, Hideya Katoh, Masaru Shimizu, Mao Kinoshita, Koichi Akiyama, Atsushi Kainuma, Kiyoshi Moriyama, Ken J. Ishii, Teiji Sawa

    Microbiology and Immunology   Vol. 61 ( 2 ) page： 64 - 74   2017

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： https://doi.org/10.1111/1348-0421.12467

  73. Vector Flow Mapping and Impaired Left Ventricular Flow After the Alfieri Stitch Reviewed

    Koichi Akiyama, Keiichi Itatani, Yoshifumi Naito, Mao Kinoshita, Masaru Shimizu, Saeko Hamaoka, Hiroaki Yasumoto, Hideya Kato, Yasufumi Nakajima, Satoshi Numata, Hitoshi Yaku, Teiji Sawa

    Journal of Cardiothoracic and Vascular Anesthesia   Vol. 31 ( 1 ) page： 211 - 214   2017

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    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： https://doi.org/10.1053/j.jvca.2016.07.013

  74. Vortex formation of single right ventricle Reviewed

    Koichi Akiyama, Maki Ishii, Keiichi Itatani, Mao Kinoshita, Atsushi Kainuma, Yasufumi Nakajima, Teiji Sawa

    Anesthesia & Analgesia   Vol. 124 ( 5S ) page： 145 - 146   2017

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    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (other academic)  

  75. Flow energetic assessment of staged palliative surgery Reviewed

    Keita Inoue, Koichi Akiyama, Mao Kinoshita, Atsushi Kainuma, Saeko Hamaoka, Yoshifumi Naito, Teiji Sawa

    Anesthesia & Analgesia   Vol. 124 ( 5S ) page： 377 - 378   2017

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  76. The relation between the direction of AR jet flows and intracardiac EL changes Reviewed

    Atsushi Kainuma, Koichi Akiyama, Yoshifumi Naito, Keita Inoue, Shusuke Takeshita, Masaru Shimizu, Teiji Sawa

    Anesthesia & Analgesia   Vol. 124 ( 5S ) page： 1152   2017

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  77. Flow-dynamics assessment of mitral-valve surgery by intraoperative vector flow mapping Reviewed

    Koichi Akiyama, Naotoshi Nakamura, Keiichi Itatani, Yoshifumi Naito, Mao Kinoshita, Masaru Shimizu, Saeko Hamaoka, Hideya Kato, Hiroaki Yasumoto, Yasufumi Nakajima, Toshiki Mizobe, Satoshi Numata, Hitoshi Yaku, Teiji Sawa

    Interactive CardioVascular and Thoracic Surgery   Vol. 24 ( 6 ) page： 869 - 875   2017

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    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： https://doi.org/10.1093/icvts/ivx033

  78. IV Immunoglobulin for Acute Lung Injury and Bacteremia in Pseudomonas aeruginosa Pneumonia Reviewed

    Hideya Katoh, Hiroaki Yasumoto, Masaru Shimizu, Saeko Hamaoka, Mao Kinoshita, Koichi Akiyama, Teiji Sawa

    Critical Care Medicine   Vol. 44 ( 1 ) page： e12 - e24   2016

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： https://doi.org/10.1097/ccm.0000000000001271

  79. Epidemiological analysis of serum anti-Pseudomonas aeruginosaPcrV titers in adults Reviewed

    Hiroaki Yasumoto, Hideya Katoh, Mao Kinoshita, Masaru Shimizu, Saeko Hamaoka, Koichi Akiyama, Yoshifumi Naito, Teiji Sawa

    Microbiology and Immunology   Vol. 60 ( 2 ) page： 114 - 120   2016

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： https://doi.org/10.1111/1348-0421.12353

  80. GDT-2D-Visualizer: The development of on-line two-dimensional SVV-SVI plotting system Reviewed

    Teiji Sawa, Koichi Akiyama, Hideya Kato

    Anesthesia & Analgesia   Vol. 122 ( 5S ) page： 346   2016

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  81. Effect of immunoglobulin on virulence of pseudomonas aeruginosa in vitro cytotoxicity assay Reviewed

    Hideya Kato, Koichi Akiyama, Masaru Shimizu, Mao Kinoshita, Saeko Hamaoka, Yoshifumi Naito, Teiji Sawa

    Anesthesia & Analgesia   Vol. 122 ( 5S ) page： 88   2016

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  82. Definition of normal vortex and energy loss reference value in left ventricle using vector flow mapping Reviewed

    Koichi Akiyama, Sachiko Maeda, Yoshifumi Naito, Hideya Kato, Mao Kinoshita, Masaru Shimizu, Teiji Sawa

    Anesthesia & Analgesia   Vol. 122 ( 5S ) page： 356   2016

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  83. Mitral valve replacement impairs left ventricular blood flow Reviewed

    Koichi Akiyama, Keiichi Itatani, Mao Kinoshita, Masaru Shimizu, Saeko Hamaoka, Hideya Kato, Yoshifumi Naito, Yasufumi Nakajima, Satoshi Numata, Toshiki Mizobe, Hitoshi Yaku, Teiji Sawa

    Journal of American College fo Cardiology   Vol. 67 ( 13 ) page： 1701   2016

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    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (other academic)  

  84. Protective effects of intravenous immunoglobulin and antimicrobial agents on acute pneumonia in leukopenic mice Reviewed

    Masaru Shimizu, Hideya Katoh, Saeko Hamaoka, Mao Kinoshita, Koichi Akiyama, Yoshifumi Naito, Teiji Sawa

    Journal of Infection and Chemotherapy   Vol. 22 ( 4 ) page： 240 - 247   2016

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： https://doi.org/10.1016/j.jiac.2016.01.006

  85. The prophylactic effects of human IgG derived from sera containing high anti-PcrV titers against pneumonia-causingPseudomonas aeruginosa Reviewed

    Mao Kinoshita, Hideya Kato, Hiroaki Yasumoto, Masaru Shimizu, Saeko Hamaoka, Yoshifumi Naito, Koichi Akiyama, Kiyoshi Moriyama, Teiji Sawa

    Human Vaccines & Immunotherapeutics   Vol. 12 ( 11 ) page： 2833 - 2864   2016

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： https://doi.org/10.1080/21645515.2016.1209280

  86. 術中Vector Flow Mappingを用いたSAM原因の究明 Reviewed

    秋山 浩一, 石井 真紀, 加藤 秀哉, 中嶋 康文, 溝部 俊樹, 佐和 貞治

    Cardiovascular Anesthesia   Vol. 20   page： 190   2016

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    Authorship：Lead author,　Corresponding author   Language：Japanese   Publishing type：Research paper (other academic)  

  87. 単心室におけるエネルギー効率 Reviewed

    秋山 浩一, 谷口 文香, 内藤 慶史, 木下 真央, 加藤 秀哉, 甲斐沼 篤, 佐和 貞治

    日本小児麻酔学会誌   Vol. 22 ( 1 ) page： 116   2016

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    Authorship：Lead author,　Corresponding author   Language：Japanese   Publishing type：Research paper (other academic)  

  88. 術中リアルタイムVector Flow Mappingを用いた僧帽弁手術評価の展望 Reviewed

    秋山 浩一, 木下 真央, 内藤 慶史, 中嶋 康文, 溝部 俊樹, 佐和 貞治

    Cardiovascular Anesthesia   Vol. 20   page： 189   2016

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    Authorship：Lead author,　Corresponding author   Language：Japanese   Publishing type：Research paper (other academic)  

  89. Pseudomonas aeruginosa Type III Secretory Toxin ExoU and Its Predicted Homologs Reviewed

    Teiji Sawa, Saeko Hamaoka, Mao Kinoshita, Atsushi Kainuma, Yoshifumi Naito, Koichi Akiyama, Hideya Kato

    Toxins   Vol. 8 ( 11 ) page： 307   2016

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： https://doi.org/10.3390/toxins8110307

  90. 小児のvalvular ASの対するRoss手術でSAMを起こした症例における血流解析 Reviewed

    秋山 浩一, 上中 智恵, 岡林 志帆子, 内藤 慶史, 柴崎 雅志, 中嶋 康文, 溝部 俊樹, 佐和 貞治

    Cardiovascular Anesthesia   Vol. 19   page： 234   2015

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    Authorship：Lead author,　Corresponding author   Language：Japanese   Publishing type：Research paper (other academic)  

  91. Genotyping the typeⅢ secretory ExoU and phenotyping cytotoxicity in carbapenem-resistant clinical isolates of pseudomonas aeruginosa Reviewed

    Koichi Akiyama, Hideya Kato, Masaru Shimizu, Saeko Hamaoka, Mao Kinoshita, Yoshifumi Naito, Teiji Sawa

    American Journal of Respiratory and Critical Care Medicine   Vol. 191 ( A ) page： 6007   2015

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  92. Intraoperative cardiac assessment with transesophageal echocardiography for decision-making in cardiac anesthesia Reviewed

    Koichi Akiyama, Shoji Arisawa, Masahiro Ide, Masaaki Iwaya, Yoshiyuki Naito

    General Thoracic and Cardiovascular Surgery   Vol. 61 ( 6 ) page： 320 - 329   2013

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    Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： https://doi.org/10.1007/s11748-013-0208-6

  93. 自己弁温存大動脈基部置換術—Dynamic Aortic RootとTEEによる評価— Reviewed

    秋山浩一

      Vol. 16 ( 2 ) page： 7 - 14   2013

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  94. 肺動脈カテーテルの縫合損傷によるオプティカル・モジュール・コネクタからの血液漏出 Reviewed

    秋山浩一, 岩谷全亮, 内藤嘉之

    麻酔   Vol. 59 ( 10 ) page： 1257 - 1259   2010

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    Authorship：Lead author   Language：Japanese   Publishing type：Research paper (scientific journal)  

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To the head of Papers.▲

KAKENHI (Grants-in-Aid for Scientific Research) 3

  1. 血流解析から得られた新しいパラメータによる心不全患者の血栓リスク定量化

    2024.4 - 2027.3

    日本学術振興会 科学研究費助成事業 基盤研究(C) 

    金澤裕子, 前田琢磨, 秋山浩一

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    Authorship：Coinvestigator(s) 

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  2. Elucidation of the pathology concerning inflammasome associated pancytopenia in severe sepsis, and its control by microRNA.

    Grant number：23K08434  2023.4 - 2026.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

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  3. Development of perioperative management in adult patients with congenital heart disease using fluid dynamics analysis and proteomics

    Grant number：22K16615  2022.4 - 2025.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Early-Career Scientists  Grant-in-Aid for Early-Career Scientists

    Koichi Akiyama

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    Authorship：Principal investigator 

    Grant amount：\4550000 （ Direct Cost: \3500000 、 Indirect Cost：\1050000 ）

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To the head of KAKENHI (Grants-in-Aid for Scientific Research).▲