Updated on 2024/10/09

写真a

 
FUNAHASHI Yoshio
 
Organization
Nagoya University Hospital Emergency and Critical Care Medicine Assistant professor of hospital
Title
Assistant professor of hospital

Degree 1

  1. 博士（医学） （ 2019.3   名古屋大学 ） 

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Research Interests 2

  1. Cardiorenal Syndrome

  2. Acute Kidney Injury

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Research Areas 1

  1. Life Science / Nephrology

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Professional Memberships 6

  1. 日本内科学会

  2. 日本腎臓学会

  3. 日本集中治療医学会

  4. 日本透析医学会

  5. 日本急性血液浄化学会

  6. 日本救急医学会

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Awards 9

  1. Best Abstract Award

    2024   67th Annual Meeting of the Japanese Society of Nephrology  

    Yoshio Funahashi

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    Award type：Award from Japanese society, conference, symposium, etc.  Country：Japan

  2. Karen L. Campbell, PhD, Travel Support Program

    2023   American Society of Nephrology Kidney Week  

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    Award type：Award from international society, conference, symposium, etc.  Country：United States

  3. Karen L. Campbell, PhD, Travel Support Program

    2022   American Society of Nephrology Kidney Week  

    Yoshio Funahashi

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    Award type：Award from international society, conference, symposium, etc.  Country：United States

  4. Travel Grant

    2019   56th ERA-EDTA Congress  

    Yoshio Funahashi

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    Award type：Award from international society, conference, symposium, etc.  Country：Hungary

  5. Excellent Abstract Award

    2019   62nd Annual Meeting of the Japanese Society of Nephrology  

    Yoshio Funahashi

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    Award type：Award from Japanese society, conference, symposium, etc.  Country：Japan

  6. Travel Award

    2018   41st Annual Conference on Shock  

    Yoshio Funahashi

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    Award type：Award from international society, conference, symposium, etc.  Country：United States

  7. Young Investigator Award

    2018   International Society of Nephrology Frontiers Meeting  

    Yoshio Funahashi

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    Award type：Award from international society, conference, symposium, etc.  Country：Japan

  8. Travel Grant

    2017   54th ERA-EDTA Congress  

    Yoshio Funahashi

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    Award type：Award from international society, conference, symposium, etc.  Country：Spain

  9. Kidney STARS

    2017   ASN Kidney Week  

    Yoshio Funahashi

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    Award type：Award from international society, conference, symposium, etc.  Country：United States

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Papers 10

  1. Nanotherapeutic kidney cell-specific targeting to ameliorate acute kidney injury Reviewed International coauthorship

    Yoshio Funahashi, Seung Hun Park, Jessica F Hebert, Mahaba B Eiwaz, Adam C Munhall, Tahnee Groat, Lingxue Zeng, Jonghan Kim, Hak Soo Choi, Michael P Hutchens

    KIDNEY INTERNATIONAL   Vol. 106 ( 4 ) page： 597 - 610   2024.10

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    Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/j.kint.2024.06.021

  2. Cilastatin Ameliorates Rhabdomyolysis-induced AKI in Mice Invited Reviewed International coauthorship

    Katsuyuki Matsushita, Kiyoshi Mori, Turgay Saritas, Mahaba B Eiwaz, Yoshio Funahashi, Megan N Nickerson, Jessica F Hebert, Adam C Munhall, James A McCormick, Motoko Yanagita, Michael P Hutchens

    Journal of the American Society of Nephrology   Vol. 32 ( 10 ) page： 2579 - 2594   2021.8

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1681/ASN.2020030263

  3. Detecting and exploring kidney-derived extracellular vesicles in plasma Reviewed

    Komatsu, S; Kato, N; Kitai, H; Funahashi, Y; Noda, Y; Tsubota, S; Tanaka, A; Sato, Y; Maeda, K; Saito, S; Furuhashi, K; Ishimoto, T; Kosugi, T; Maruyama, S; Kadomatsu, K

    CLINICAL AND EXPERIMENTAL NEPHROLOGY   Vol. 28 ( 7 ) page： 617 - 628   2024.7

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Clinical and Experimental Nephrology  

    Background: Extracellular vesicles (EVs) have received considerable attention as ideal biomarkers for kidney diseases. Most reports have focused on urinary EVs, that are mainly derived from the cells in the urinary tract. However, the detection and the application of kidney-derived EVs in plasma remains uncertain. Methods: We examined the kidney-derived small EVs (sEVs) in plasma that were supposedly released from renal mesangial and glomerular endothelial cells, using clinical samples from healthy controls and patients with kidney transplants. Plasma from healthy controls underwent ultracentrifugation, followed by on-bead flow cytometry, targeting α8 integrin, an antigen-specific to mesangial cells. To confirm the presence of kidney-derived sEVs in peripheral blood, plasma from ABO-incompatible kidney transplant recipients was ultracentrifuged, followed by western blotting for donor blood type antigens. Results: Immunohistochemistry and immunoelectron microscopy confirmed α8 integrin expression in kidney mesangial cells and their sEVs. The CD9-α8 integrin double-positive sEVs were successfully detected using on-bead flow cytometry. Western blot analysis further revealed transplanted kidney-derived sEVs containing blood type B antigens in non-blood type B recipients, who had received kidneys from blood type B donors. Notably, a patient experiencing graft kidney loss exhibited diminished signals of sEVs containing donor blood type antigens. Conclusion: Our findings demonstrate the potential usefulness of kidney-derived sEVs in plasma in future research for kidney diseases.

    DOI： 10.1007/s10157-024-02464-z

    Web of Science

    Scopus

    PubMed

  4. Share Parental recovered acute kidney injury causes prenatal renal dysfunction and fetal growth restriction with sexually dimorphic implications for adult offspring. Reviewed

    Jessica F Hebert, Yoshio Funahashi, Jacqueline M Emathinger, Megan N Nickerson, Tahnee Groat, Nicole K Andeen, Susan B Gurley, Michael P Hutchens

    Frontiers Phsysiology     2024.4

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    Language：English  

    DOI： 10.3389/fphys.2024.1357932

  5. Natural Killer Lymphocytes Mediate Renal Fibrosis Due to Acute Cardiorenal Syndrome. Reviewed

    Kevin G Burfeind, Yoshio Funahashi, Adam C Munhall, Michael P Hutchens

    Kidney360   Vol. 5 ( 1 ) page： 8 - 21   2024.1

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    Authorship：Lead author   Language：English  

  6. Harm! foul! How acute kidney injury SHReDDs patient futures. Reviewed

    Jessica F Hebert, Yoshio Funahashi, Michael P Hutchens

    Current Opinion in Nephrology and Hypertension   Vol. 32 ( 2 ) page： 165 - 171   2023.3

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    Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1097/MNH.0000000000000864

  7. Systematic characterization of seed overlap microRNA cotargeting associated with lupus pathogenesis Reviewed

    Kitai H, Kato N, Ogami K, Komatsu S, Watanabe Y, Yoshino S, Koshi E, Tsubota S, Funahashi Y, Maeda T, Furuhashi K, Ishimoto T, Kosugi T, Maruyama S, Kadomatsu K, Suzuki HI.

    BMC Biology   Vol. 20 ( 1 ) page： 248   2022.11

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1186/s12915-022-01447-4

  8. Renal injury in cardiorenal syndrome type 1 is mediated by albumin Invited Reviewed International coauthorship

    Yoshio Funahashi, Mizuko Ikeda, Rumie Wakasaki, Sheuli Chowdhury, Tahnee Groat, Douglas Zeppenfeld, Michael P. Hutchens

    Physiological Reports     2022.2

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    Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.14814/phy2.15173

  9. Acute Cardiorenal Syndrome: Models and Heart-Kidney Connectors Reviewed

    Yoshio Funahashi, Sheuli Chowdhury, Mahaba B Eiwaz, Michael P Hutchens

    Nephron   Vol. 144 ( 12 ) page： 629 - 633   2020.8

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    Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1159/000509353

  10. miR-146a targeted to splenic macrophages prevents sepsis-induced multiple organ injury Reviewed

    Yoshio Funahashi, Noritoshi Kato, Tomohiro Masuda, Fumitoshi Nishio, Hiroki Kitai, Takuji Ishimoto, Tomoki Kosugi, Naotake Tsuboi, Naoyuki Matsuda, Shoichi Maruyama, Kenji Kadomatsu

    Laboratory Investigation   Vol. 99 ( 8 ) page： 1130 - 1142   2019.1

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    Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1038/s41374-019-0190-4

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Books 1

  1. 敗血症治療に対する核酸医薬開発と課題

    船橋嘉夫（ Role： Contributor）

    医学のあゆみ　医師薬出版株式会社  2019 

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    Total pages：2   Language：Japanese Book type：Scholarly book

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