Meta-Analysisof Gut Dysbiosis in Parkinson's Disease

Nishiwaki Hiroshi, Ito Mikako, Ishida Tomohiro, Hamaguchi Tomonari, Maeda Tetsuya, Kashihara Kenichi, Tsuboi Yoshio, Ueyama Jun, Shimamura Teppei, Mori Hiroshi, Kurokawa Ken, Katsuno Masahisa, Hirayama Masaaki, Ohno Kinji

MOVEMENT DISORDERS   35 巻 ( 9 ) 頁： 1626 - 1635   2020年9月

ARHGAP10, which encodes Rho GTPase-activating protein 10, is a novel gene for schizophrenia risk

Sekiguchi Mariko, Sobue Akira, Kushima Itaru, Wang Chenyao, Arioka Yuko, Kato Hidekazu, Kodama Akiko, Kubo Hisako, Ito Norimichi, Sawahata Masahito, Hada Kazuhiro, Ikeda Ryosuke, Shinno Mio, Mizukoshi Chikara, Tsujimura Keita, Yoshimi Akira, Ishizuka Kanako, Takasaki Yuto, Kimura Hiroki, Xing Jingrui, Yu Yanjie, Yamamoto Maeri, Okada Takashi, Shishido Emiko, Inada Toshiya, Nakatochi Masahiro, Takano Tetsuya, Kuroda Keisuke, Amano Mutsuki, Aleksic Branko, Yamomoto Takashi, Sakuma Tetsushi, Aida Tomomi, Tanaka Kohichi, Hashimoto Ryota, Arai Makoto, Ikeda Masashi, Iwata Nakao, Shimamura Teppei, Nagai Taku, Nabeshima Toshitaka, Kaibuchi Kozo, Yamada Kiyofumi, Mori Daisuke, Ozaki Norio

TRANSLATIONAL PSYCHIATRY   10 巻 ( 1 ) 頁： 247   2020年7月

Integrated multiomics analysis of hepatoblastoma unravels its heterogeneity and provides novel druggable targets

Sekiguchi Masahiro, Seki Masafumi, Kawai Tomoko, Yoshida Kenichi, Yoshida Misa, Isobe Tomoya, Hoshino Noriko, Shirai Ryota, Tanaka Mio, Souzaki Ryota, Watanabe Kentaro, Arakawa Yuki, Nannya Yasuhito, Suzuki Hiromichi, Fujii Yoichi, Kataoka Keisuke, Shiraishi Yuichi, Chiba Kenichi, Tanaka Hiroko, Shimamura Teppei, Sato Yusuke, Sato-Otsubo Aiko, Kimura Shunsuke, Kubota Yasuo, Hiwatari Mitsuteru, Koh Katsuyoshi, Hayashi Yasuhide, Kanamori Yutaka, Kasahara Mureo, Kohashi Kenichi, Kato Motohiro, Yoshioka Takako, Matsumoto Kimikazu, Oka Akira, Taguchi Tomoaki, Sanada Masashi, Tanaka Yukichi, Miyano Satoru, Hata Kenichiro, Ogawa Seishi, Takita Junko

NPJ PRECISION ONCOLOGY   4 巻 ( 1 ) 頁： 20   2020年7月

EXOSC9 depletion attenuates P-body formation, stress resistance, and tumorigenicity of cancer cells

Yoshino Seiko, Matsui Yusuke, Fukui Yuya, Seki Masahide, Yamaguchi Kiyoshi, Kanamori Akane, Saitoh Yurika, Shimamura Teppei, Suzuki Yutaka, Furukawa Yoichi, Kaneko Shuichi, Seiki Motoharu, Murakami Yoshinori, Inoue Jun-ichiro, Sakamoto Takeharu

SCIENTIFIC REPORTS   10 巻 ( 1 ) 頁： 9275   2020年6月

Coordinated demethylation of H3K9 and H3K27 is required for rapid inflammatory responses of endothelial cells

Higashijima Yoshiki, Matsui Yusuke, Shimamura Teppei, Nakaki Ryo, Nagai Nao, Tsutsumi Shuichi, Abe Yohei, Link Verena M., Osaka Mizuko, Yoshida Masayuki, Watanabe Ryo, Tanaka Toshihiro, Taguchi Akashi, Miura Mai, Ruan Xiaoan, Li Guoliang, Inoue Tsuyoshi, Nangaku Masaomi, Kimura Hiroshi, Furukawa Tetsushi, Aburatani Hiroyuki, Wada Youichiro, Ruan Yijun, Glass Christopher K., Kanki Yasuharu

EMBO JOURNAL   39 巻 ( 7 ) 頁： e103949   2020年4月

Model-based cell clustering and population tracking for time-series flow cytometry data

Minoura Kodai, Abe Ko, Maeda Yuka, Nishikawa Hiroyoshi, Shimamura Teppei

BMC BIOINFORMATICS   20 巻 ( 1 ) 頁： 633   2019年12月

Meflin-Positive Cancer-Associated Fibroblasts Inhibit Pancreatic Carcinogenesis

Mizutani Yasuyuki, Kobayashi Hiroki, Iida Tadashi, Asai Naoya, Masamune Atsushi, Hara Akitoshi, Esaki Nobutoshi, Ushida Kaori, Mii Shinji, Shiraki Yukihiro, Ando Kenju, Weng Liang, Ishihara Seiichiro, Ponik Suzanne M., Conklin Matthew W., Haga Hisashi, Nagasaka Arata, Miyata Takaki, Matsuyama Makoto, Kobayashi Tomoe, Fujii Tsutomu, Yamada Suguru, Yamaguchi Junpei, Wang Tongtong, Woods Susan L., Worthley Daniel, Shimamura Teppei, Fujishiro Mitsuhiro, Hirooka Yoshiki, Enomoto Atsushi, Takahashi Masahide

CANCER RESEARCH   79 巻 ( 20 ) 頁： 5367 - 5381   2019年10月

Pathogenic Epigenetic Consequences of Genetic Alterations in IDH-Wild-Type Diffuse Astrocytic Gliomas

Ohka Fumiharu, Shinjo Keiko, Deguchi Shoichi, Matsui Yusuke, Okuno Yusuke, Katsushima Keisuke, Suzuki Miho, Kato Akira, Ogiso Noboru, Yamamichi Akane, Aoki Kosuke, Suzuki Hiromichi, Sato Shinya, Rayan Nirmala Arul, Prabhakar Shyam, Goke Jonathan, Shimamura Teppei, Maruyama Reo, Takahashi Satoru, Suzumura Akio, Kimura Hiroshi, Wakabayashi Toshihiko, Zong Hui, Natsume Atsushi, Kondo Yutaka

CANCER RESEARCH   79 巻 ( 19 ) 頁： 4814 - 4827   2019年10月

Phosphoethanolamine Accumulation Protects Cancer Cells under Glutamine Starvation through Downregulation of PCYT2

Osawa Tsuyoshi, Shimamura Teppei, Saito Kyoko, Hasegawa Yoko, Ishii Naoko, Nishida Miyuki, Ando Ritsuko, Kondo Ayano, Anwar Muyassar, Tsuchida Rika, Hino Shinjiro, Sakamoto Akihisa, Igarashi Kaori, Saitoh Kaori, Kato Keiko, Endo Keiko, Yamano Shotaro, Kanki Yasuharu, Matsumura Yoshihiro, Minami Takashi, Tanaka Toshiya, Anai Motonobu, Wada Youichiro, Wanibuchi Hideki, Hayashi Mitsuhiro, Hamada Akinobu, Yoshida Masayuki, Yachida Shinichi, Nakao Mitsuyoshi, Sakai Juro, Aburatani Hiroyuki, Shibuya Masabumi, Hanada Kentaro, Miyano Satoru, Soga Tomoyoshi, Kodama Tatsuhiko

CELL REPORTS   29 巻 ( 1 ) 頁： 89 - +   2019年10月

Divergent lncRNA MYMLR regulates MYC by eliciting DNA looping and promoter-enhancer interaction

Kajino Taisuke, Shimamura Teppei, Gong Shuyi, Yanagisawa Kiyoshi, Ida Lisa, Nakatochi Masahiro, Griesing Sebastian, Shimada Yukako, Kano Keiko, Suzuki Motoshi, Miyano Satoru, Takahashi Takashi

EMBO JOURNAL   38 巻 ( 17 )   2019年9月

Divergent lncRNA MYMLR regulates MYC by eliciting DNA looping and promoter-enhancer interaction.

Kajino T, Shimamura T, Gong S, Yanagisawa K, Ida L, Nakatochi M, Griesing S, Shimada Y, Kano K, Suzuki M, Miyano S, Takahashi T

The EMBO journal   38 巻 ( 17 ) 頁： e98441   2019年9月

Replication stress triggers microsatellite destabilization and hypermutation leading to clonal expansion in vitro

Matsuno Yusuke, Atsumi Yuko, Shimizu Atsuhiro, Katayama Kotoe, Fujimori Haruka, Hyodo Mai, Minakawa Yusuke, Nakatsu Yoshimichi, Kaneko Syuzo, Hamamoto Ryuji, Shimamura Teppei, Miyano Satoru, Tsuzuki Teruhisa, Hanaoka Fumio, Yoshioka Ken-ichi

NATURE COMMUNICATIONS   10 巻 ( 1 ) 頁： 3925   2019年9月

A network of networks approach for modeling interconnected brain tissue-specific networks

Kawakubo Hideko, Matsui Yusuke, Kushima Itaru, Ozaki Norio, Shimamura Teppei

BIOINFORMATICS   35 巻 ( 17 ) 頁： 3092 - 3101   2019年9月

Distinct methylation levels of mature microRNAs in gastrointestinal cancers

Konno Masamitsu, Koseki Jun, Asai Ayumu, Yamagata Akira, Shimamura Teppei, Motooka Daisuke, Okuzaki Daisuke, Kawamoto Koichi, Mizushima Tsunekazu, Eguchi Hidetoshi, Takiguchi Shuji, Satoh Taroh, Mimori Koshi, Ochiya Takahiro, Doki Yuichiro, Ofusa Ken, Mori Masaki, Ishii Hideshi

NATURE COMMUNICATIONS   10 巻 ( 1 ) 頁： 3888   2019年8月

Myxofibrosarcoma is characterized by frequent abnormalities in TP53 and increased genetic instability

Takeuchi Yasuhide, Kunitz Annegret, Suzuki Hiromichi, Yoshida Kenichi, Shiraishi Yuichi, Chiba Kenichi, Tanaka Hiroko, Shimamura Teppei, Kakiuchi Nobuyuki, Shiozawa Yusuke, Yokoyama Akira, Yoshizato Tetsuichi, Aoki Kosuke, Fujii Yoichi, Nannya Yasuhito, Makishima Hideki, Miyano Satoru, Haga Hironori, Damm Frederik, Ogawa Seishi

CANCER RESEARCH   79 巻 ( 13 )   2019年7月

ENIGMA: an enterotype-like unigram mixture model for microbial association analysis

Abe Ko, Hirayama Masaaki, Ohno Kinji, Shimamura Teppei

BMC GENOMICS   20 巻 ( Suppl 2 ) 頁： 191   2019年4月

Regnase-1-mediated post-transcriptional regulation is essential for hematopoietic stem and progenitor cell homeostasis

Kidoya Hiroyasu, Muramatsu Fumitaka, Shimamura Teppei, Jia Weizhen, Satoh Takashi, Hayashi Yumiko, Naito Hisamichi, Kunisaki Yuya, Arai Fumio, Seki Masahide, Suzuki Yutaka, Osawa Tsuyoshi, Akira Shizuo, Takakura Nobuyuki

NATURE COMMUNICATIONS   10 巻 ( 1 ) 頁： 1072   2019年3月

A latent allocation model for the analysis of microbial composition and disease

Abe Ko, Hirayama Masaaki, Ohno Kinji, Shimamura Teppei

BMC BIOINFORMATICS   19 巻 ( Suppl 19 ) 頁： 519   2018年12月

Metabolic Alterations Promotes Tumor Progression under Amino Acids deprivation

Osawa Tsuyoshi, Shimamura Teppei, Kondo Ayano, Tsuchida Rika, Miyano Satoru, Aburatani Hiroyuki, Shibuya Masabumi, Kodama Tatsuhiko

CANCER SCIENCE   109 巻   頁： 194 - 194   2018年12月

Comparative Analyses of Copy-Number Variation in Autism Spectrum Disorder and Schizophrenia Reveal Etiological Overlap and Biological Insights

Kushima Itaru, Aleksic Branko, Nakatochi Masahiro, Shimamura Teppei, Okada Takashi, Uno Yota, Morikawa Mako, Ishizuka Kanako, Shiino Tomoko, Kimura Hiroki, Arioka Yuko, Yoshimi Akira, Takasaki Yuto, Yu Yanjie, Nakamura Yukako, Yamamoto Maeri, Iidaka Tetsuya, Iritani Shuji, Inada Toshiya, Ogawa Nanayo, Shishido Emiko, Torii Youta, Kawano Naoko, Omura Yutaka, Yoshikawa Toru, Uchiyama Tokio, Yamamoto Toshimichi, Ikeda Masashi, Hashimoto Ryota, Yamamori Hidenaga, Yasuda Yuka, Someya Toshiyuki, Watanabe Yuichiro, Egawa Jun, Nunokawa Ayako, Itokawa Masanari, Arai Makoto, Miyashita Mitsuhiro, Kobori Akiko, Suzuki Michio, Takahashi Tsutomu, Usami Masahide, Kodaira Masaki, Watanabe Kyota, Sasaki Tsukasa, Kuwabara Hitoshi, Tochigi Mamoru, Nishimura Fumichika, Yamasue Hidenori, Eriguchi Yosuke, Benner Seico, Kojima Masaki, Yassin Walid, Munesue Toshio, Yokoyama Shigeru, Kimura Ryo, Funabiki Yasuko, Kosaka Hirotaka, Ishitobi Makoto, Ohmori Tetsuro, Numata Shusuke, Yoshikawa Takeo, Toyota Tomoko, Yamakawa Kazuhiro, Suzuki Toshimitsu, Inoue Yushi, Nakaoka Kentaro, Goto Yu-ichi, Inagaki Masumi, Hashimoto Naoki, Kusumi Ichiro, Son Shuraku, Murai Toshiya, Ikegame Tempei, Okada Naohiro, Kasai Kiyoto, Kunimoto Shohko, Mori Daisuke, Iwata Nakao, Ozaki Norio

CELL REPORTS   24 巻 ( 11 ) 頁： 2838 - 2856   2018年9月

A temporal shift of the evolutionary principle shaping intratumor heterogeneity in colorectal cancer

Saito Tomoko, Niida Atsushi, Uchi Ryutaro, Hirata Hidenari, Komatsu Hisateru, Sakimura Shotaro, Hayashi Shuto, Nambara Sho, Kuroda Yosuke, Ito Shuhei, Eguchi Hidetoshi, Masuda Takaaki, Sugimachi Keishi, Tobo Taro, Nishida Haruto, Daa Tsutomu, Chiba Kenichi, Shiraishi Yuichi, Yoshizato Tetsuichi, Kodama Masaaki, Okimoto Tadayoshi, Mizukami Kazuhiro, Ogawa Ryo, Okamoto Kazuhisa, Shuto Mitsutaka, Fukuda Kensuke, Matsui Yusuke, Shimamura Teppei, Hasegawa Takanori, Doki Yuichiro, Nagayama Satoshi, Yamada Kazutaka, Kato Mamoru, Shibata Tatsuhiro, Mori Masaki, Aburatani Hiroyuki, Murakami Kazunari, Suzuki Yutaka, Ogawa Seishi, Miyano Satoru, Mimori Koshi

NATURE COMMUNICATIONS   9 巻 ( 1 ) 頁： 2884   2018年7月

ATR inhibition controls aggressive prostate tumors deficient in Y-linked histone demethylase KDM5D

Komura Kazumasa, Yoshikawa Yuki, Shimamura Teppei, Chakraborty Goutam, Gerke Travis A., Hinohara Kunihiko, Chadalavada Kalyani, Jeong Seong Ho, Armenia Joshua, Du Shin-Yi, Mazzu Ying Z., Taniguchi Kohei, Ibuki Naokazu, Meyer Clifford A., Nanjangud Gouri J., Inamoto Teruo, Lee Gwo-Shu Mary, Mucci Lorelei A., Azuma Haruhito, Sweeney Christopher J., Kantoff Philip W.

JOURNAL OF CLINICAL INVESTIGATION   128 巻 ( 7 ) 頁： 2979 - 2995   2018年7月

Comprehensive analysis of genetic alterations and intratumor heterogeneity in myxofibrosarcoma

Takeuchi Yasuhide, Kunitz Annegret, Suzuki Hiromichi, Yoshida Kenichi, Kakiuchi Nobuyuki, Shiozawa Yusuke, Yokoyama Akira, Fujii Yoichi, Yoshizato Tetsuichi, Aoki Kosuke, Kataoka Keisuke, Nannya Yasuhito, Shiraishi Yuichi, Shimamura Teppei, Chiba Kenichi, Tanaka Hiroko, Makishima Hideki, Miyano Satoru, Haga Hironori, Damm Frederik, Ogawa Seishi

CANCER RESEARCH   78 巻 ( 13 )   2018年7月

Divergent lncRNA MYMLR regulates MYC by eliciting DNA looping and promoter-enhancer interaction

Kajino Taisuke, Shimamura Teppei, Gong Shuyi, Yanagisawa Kiyoshi, Nakatochi Masahiro, Griesing Sebastian, Shimada Yukako, Kano Keiko, Suzuki Motoshi, Miyano Satoru, Takahashi Takashi

CANCER RESEARCH   78 巻 ( 13 )   2018年7月

ER Stress Signaling Promotes the Survival of Cancer "Persister Cells" Tolerant to EGFR Tyrosine Kinase Inhibitors

Terai Hideki, Kitajima Shunsuke, Potter Danielle S., Matsui Yusuke, Quiceno Laura Gutierrez, Chen Ting, Kim Tae-jung, Rusan Maria, Thai Tran C., Piccioni Federica, Donovan Katherine A., Kwiatkowski Nicholas, Hinohara Kunihiko, Wei Guo, Gray Nathanael S., Fischer Eric S., Wong Kwok-Kin, Shimamura Teppei, Letai Anthony, Hammerman Peter S., Barbie David A.

CANCER RESEARCH   78 巻 ( 4 ) 頁： 1044 - 1057   2018年2月

Integrated Molecular Characterization of the Lethal Pediatric Cancer Pancreatoblastoma

Isobe Tomoya, Seki Masafumi, Yoshida Kenichi, Sekiguchi Masahiro, Shiozawa Yusuke, Shiraishi Yuichi, Kimura Shunsuke, Yoshida Misa, Inoue Yoshikage, Yokoyama Akira, Kakiuchi Nobuyuki, Suzuki Hiromichi, Kataoka Keisuke, Sato Yusuke, Kawai Tomoko, Chiba Kenichi, Tanaka Hiroko, Shimamura Teppei, Kato Motohiro, Iguchi Akihiro, Hama Asahito, Taguchi Tomoaki, Akiyama Masaharu, Fujimura Junya, Inoue Akiko, Ito Tsuyoshi, Deguchi Takao, Kiyotani Chikako, Iehara Tomoko, Hosoi Hajime, Oka Akira, Sanada Masashi, Tanaka Yukichi, Hata Kenichiro, Miyano Satoru, Ogawa Seishi, Takita Junko

CANCER RESEARCH   78 巻 ( 4 ) 頁： 865 - 876   2018年2月

Adaptive NetworkProfiler for Identifying Cancer Characteristic-Specific Gene Regulatory Networks

Park Heewon, Shimamura Teppei, Imoto Seiya, Miyano Satoru

JOURNAL OF COMPUTATIONAL BIOLOGY   25 巻 ( 2 ) 頁： 130 - 145   2018年2月

Comprehensive genetic analysis of donor cell derived leukemia with KMT2A rearrangement

Taniguchi Rieko, Muramatsu Hideki, Okuno Yusuke, Suzuki Kyogo, Obu Satoshi, Nakatochi Masahiro, Shimamura Teppei, Takahashi Yoshiyuki, Horikoshi Yasuo, Watanabe Kenichiro, Kojima Seiji

PEDIATRIC BLOOD & CANCER   65 巻 ( 2 )   2018年2月

Identification of Cardiomyocyte-Fated Progenitors from Human-Induced Pluripotent Stem Cells Marked with CD82

Takeda Masafumi, Kanki Yasuharu, Masumoto Hidetoshi, Funakoshi Shunsuke, Hatani Takeshi, Fukushima Hiroyuki, Izumi-Taguchi Akashi, Matsui Yusuke, Shimamura Teppei, Yoshida Yoshinori, Yamashita Jun K.

CELL REPORTS   22 巻 ( 2 ) 頁： 546 - 556   2018年1月

Long non-coding RNA X promotes tumor growth by regulating angiogenesis in response to nutrient starvation

Kondo Ayano, Nonaka Aya, Shimamura Teppei, Yamamoto Shogo, Yoshida Tetsuo, Kodama Tatsuhiko, Aburatani Hiroyuki, Osawa Tsuyoshi

CANCER SCIENCE   109 巻   頁： 120 - 120   2018年1月

Prognostic relevance of genetic alterations in diffuse lower-grade gliomas

Aoki Kosuke, Nakamura Hideo, Suzuki Hiromichi, Matsuo Keitaro, Kataoka Keisuke, Shimamura Teppei, Motomura Kazuya, Ohka Fumiharu, Shiina Satoshi, Yamamoto Takashi, Nagata Yasunobu, Yoshizato Tetsuichi, Mizoguchi Masahiro, Abe Tatsuya, Momii Yasutomo, Muragaki Yoshihiro, Watanabe Reiko, Ito Ichiro, Sanada Masashi, Yajima Hironori, Morita Naoya, Takeuchi Ichiro, Miyano Satoru, Wakabayashi Toshihiko, Ogawa Seishi, Natsume Atsushi

NEURO-ONCOLOGY   20 巻 ( 1 ) 頁： 66 - 77   2018年1月

Systems biology-based identification of MYMLR lncRNA modulating MYC oncogene

Kajino Taisuke, Shimamura Teppei, Gong Shuyi, Yanagisawa Kiyoshi, Nakatochi Masahiro, Griesing Sebastian, Shimada Yukako, Kano Keiko, Miyano Satoru, Takahashi Takashi

CANCER SCIENCE   109 巻   頁： 399 - 399   2018年1月

Comprehensive Analysis of Genetic Alterations and Intratumor Heterogeneity in Myxofibrosarcoma

Takeuchi Yasuhide, Suzuki Hiromichi, Yoshida Kenichi, Shiraish Yuichi, Shimamura Teppei, Yoshizato Tetsuichi, Shiozawa Yusuke, Chiba Kenichi, Makishima Hideki, Miyano Satoru, Haga Hironori, Damm Frederik, Ogawa Seishi

CANCER SCIENCE   109 巻   頁： 716 - 716   2018年1月

Japanese genome-wide association study identifies a significant colorectal cancer susceptibility locus at chromosome 10p14

Takahashi Yusuke, Sugimachi Keishi, Yamamoto Ken, Niida Atsushi, Shimamura Teppei, Sato Tetsuya, Watanabe Masahiko, Tanaka Junichi, Kudo Shinei, Sugihara Kenichi, Hase Kazuo, Kusunoki Masato, Yamada Kazutaka, Shimada Yasuhiro, Moriya Yoshihiro, Suzuki Yutaka, Miyano Satoru, Mori Masaki, Mimori Koshi

CANCER SCIENCE   108 巻 ( 11 ) 頁： 2239 - 2247   2017年11月

PRC2-Mediated Transcriptomic Alterations at the Embryonic Stage Govern Tumorigenesis and Clinical Outcome in MYCN-Driven Neuroblastoma

Tsubota Shoma, Kishida Satoshi, Shimamura Teppei, Ohira Miki, Yamashita Satoshi, Cao Dongliang, Kiyonari Shinichi, Ushijima Toshikazu, Kadomatsu Kenji

CANCER RESEARCH   77 巻 ( 19 ) 頁： 5259 - 5271   2017年10月

Long Noncoding RNA JHDM1D-AS1 Promotes Tumor Growth by Regulating Angiogenesis in Response to Nutrient Starvation

Kondo Ayano, Nonaka Aya, Shimamura Teppei, Yamamoto Shogo, Yoshida Tetsuo, Kodama Tatsuhiko, Aburatani Hiroyuki, Osawae Tsuyoshi

MOLECULAR AND CELLULAR BIOLOGY   37 巻 ( 18 )   2017年9月

Recurrent SPI1 (PU.1) fusions in high-risk pediatric T cell acute lymphoblastic leukemia

Seki Masafumi, Kimura Shunsuke, Isobe Tomoya, Yoshida Kenichi, Ueno Hiroo, Nakajima-Takagi Yaeko, Wang Changshan, Lin Lin, Kon Ayana, Suzuki Hiromichi, Shiozawa Yusuke, Kataoka Keisuke, Fujii Yoichi, Shiraishi Yuichi, Chiba Kenichi, Tanaka Hiroko, Shimamura Teppei, Masuda Kyoko, Kawamoto Hiroshi, Ohki Kentaro, Kato Motohiro, Arakawa Yuki, Koh Katsuyoshi, Hanada Ryoji, Moritake Hiroshi, Akiyama Masaharu, Kobayashi Ryoji, Deguchi Takao, Hashii Yoshiko, Imamura Toshihiko, Sato Atsushi, Kiyokawa Nobutaka, Oka Akira, Hayashi Yasuhide, Takagi Masatoshi, Manabe Atsushi, Ohara Akira, Horibe Keizo, Sanada Masashi, Iwama Atsushi, Mano Hiroyuki, Miyano Satoru, Ogawa Seishi, Takita Junko

NATURE GENETICS   49 巻 ( 8 ) 頁： 1274 - +   2017年8月

IDENTIFICATIONS OF NOVEL RECURRENT PU.1 FUSIONS WITH HIGHLY AGGRESSIVE PHENOTYPE IN PEDIATRIC T CELL ACUTE LYMPHOBLASTIC LEUKEMIA

Seki M., Kimura S., Isobe T., Yoshida K., Ueno H., Suzuki H., Shiozawa Y., Kataoka K., Fujii Y., Shiraishi Y., Chiba K., Tanaka H., Shimamura T., Lin L., Takagi M., Wang C., Iwama A., Ohki K., Kato M., Arakawa Y., Koh K., Hanada R., Moritake H., Akiyama M., Kobayashi R., Deguchi T., Hashii Y., Imamura T., Sato A., Kiyokawa N., Oka A., Hayashi Y., Manabe A., Ohara A., Horibe K., Sanada M., Mano H., Miyano S., Ogawa S., Takita J.

HAEMATOLOGICA   102 巻   頁： 327 - 328   2017年6月

Dynamically and epigenetically coordinated GATA/ETS/SOX transcription factor expression is indispensable for endothelial cell differentiation

Kanki Yasuharu, Nakaki Ryo, Shimamura Teppei, Matsunaga Taichi, Yamamizu Kohei, Katayama Shiori, Suehiro Jun-ichi, Osawa Tsuyoshi, Aburatani Hiroyuki, Kodama Tatsuhiko, Wada Youichiro, Yamashita Jun K., Minami Takashi

NUCLEIC ACIDS RESEARCH   45 巻 ( 8 ) 頁： 4344 - 4358   2017年5月

phyC: Clustering cancer evolutionary trees

Matsui Yusuke, Niida Atsushi, Uchi Ryutaro, Mimori Koshi, Miyano Satoru, Shimamura Teppei

PLOS COMPUTATIONAL BIOLOGY   13 巻 ( 5 ) 頁： e1005509   2017年5月

Correction: Integrated Multiregional Analysis Proposing a New Model of Colorectal Cancer Evolution.

Uchi R, Takahashi Y, Niida A, Shimamura T, Hirata H, Sugimachi K, Sawada G, Iwaya T, Kurashige J, Shinden Y, Iguchi T, Eguchi H, Chiba K, Shiraishi Y, Nagae G, Yoshida K, Nagata Y, Haeno H, Yamamoto H, Ishii H, Doki Y, Iinuma H, Sasaki S, Nagayama S, Yamada K, Yachida S, Kato M, Shibata T, Oki E, Saeki H, Shirabe K, Oda Y, Maehara Y, Komune S, Mori M, Suzuki Y, Yamamoto K, Aburatani H, Ogawa S, Miyano S, Mimori K

PLoS genetics   13 巻 ( 5 ) 頁： e1006798   2017年5月

High-resolution copy number variation analysis of schizophrenia in Japan

Kushima I., Aleksic B., Nakatochi M., Shimamura T., Shiino T., Yoshimi A., Kimura H., Takasaki Y., Wang C., Xing J., Ishizuka K., Oya-Ito T., Nakamura Y., Arioka Y., Maeda T., Yamamoto M., Yoshida M., Noma H., Hamada S., Morikawa M., Uno Y., Okada T., Iidaka T., Iritani S., Yamamoto T., Miyashita M., Kobori A., Arai M., Itokawa M., Cheng M-C, Chuang Y-A, Chen C-H, Suzuki M., Takahashi T., Hashimoto R., Yamamori H., Yasuda Y., Watanabe Y., Nunokawa A., Someya T., Ikeda M., Toyota T., Yoshikawa T., Numata S., Ohmori T., Kunimoto S., Mori D., Iwata N., Ozaki N.

MOLECULAR PSYCHIATRY   22 巻 ( 3 ) 頁： 430 - 440   2017年3月

Extracellular Acidic pH Activates the Sterol Regulatory Element-Binding Protein 2 to Promote Tumor Progression

Kondo Ayano, Yamamoto Shogo, Nakaki Ryo, Shimamura Teppei, Hamakubo Takao, Sakai Juro, Kodama Tatsuhiko, Yoshida Tetsuo, Aburatani Hiroyuki, Osawa Tsuyoshi

CELL REPORTS   18 巻 ( 9 ) 頁： 2228 - 2242   2017年2月

Aberrant Methylation of FOXE1 Contributes to a Poor Prognosis for Patients with Colorectal Cancer 査読有り

Sugimachi K, Matsumura T, Shimamura T, Hirata H, Uchi R, Ueda M, Sakimura S, Iguchi T, Eguchi H, Masuda T, Morita K, Takenaka K, Maehara Y, Mori M, Mimori K

Ann Surg Oncol   23 巻 ( 12 ) 頁： 3948-3955   2016年11月

D3M: detection of differential distributions of methylation levels 査読有り

Matsui Y, Mizuta M, Ito S, Miyano S, Shimamura T

Bioinformatics   32 巻 ( 15 ) 頁： 2248-2255   2016年8月

NECAB3 Promotes Activation of Hypoxia-inducible factor-1 during Normoxia and Enhances Tumourigenicity of Cancer Cells 査読有り

Nakaoka HJ, Hara T, Yoshino S, Kanamori A, Matsui Y, Shimamura T, Sato H, Murakami Y, Seiki M, Sakamoto T

Sci Rep   6 巻   頁： 22784   2016年5月

Genomic Landscape of Esophageal Squamous Cell Carcinoma in a Japanese Population

Sawada G, Niida A, Uchi R, Hirata H, Shimamura T, Suzuki Y, Shiraishi Y, Chiba K, Imoto S, Takahashi Y, Iwaya T, Sudo T, Hayashi T, Takai H, Kawasaki Y, Matsukawa T, Eguchi H, Sugimachi K, Tanaka F, Suzuki H, Yamamoto K, Ishii H, Shimizu M, Yamazaki H, Yamazaki M, Tachimori Y, Kajiyama Y, Natsugoe S, Fujita H, Mafune K, Tanaka Y, Kelsell DP, Scott CA, Tsuji S, Yachida S, Shibata T, Sugano S, Doki Y, Akiyama T, Aburatani H, Ogawa S, Miyano S, Mori M, Mimori K

Gastroenterology   150 巻 ( 5 ) 頁： 1171-1182   2016年5月

Integrated Multiregional Analysis Proposing a New Model of Colorectal Cancer Evolution 査読有り

Uchi R, Takahashi Y, Niida A, Shimamura T, Hirata H, Sugimachi K, Sawada G, Iwaya T, Kurashige J, Shinden Y, Iguchi T, Eguchi H, Chiba K, Shiraishi Y, Nagae G, Yoshida K, Nagata Y, Haeno H, Yamamoto H, Ishii H, Doki Y, Iinuma H, Sasaki S, Nagayama S, Yamada K, Yachida S, Kato M, Shibata T, Oki E, Saeki H, Shirabe K, Oda Y, Maehara Y, Komune S, Mori M, Suzuki Y, Yamamoto K, Aburatani H, Ogawa S, Miyano S, Mimori K

PLoS Genet   12 巻 ( 2 ) 頁： e1005778   2016年2月

An Integrative Analysis to Identify Driver Genes in Esophageal Squamous Cell Carcinoma 査読有り

Sawada G, Niida A, Hirata H, Komatsu H, Uchi R, Shimamura T, Takahashi Y, Kurashige J, Matsumura T, Ueo H, Takano Y, Ueda M, Sakimura S, Shinden Y, Eguchi H, Sudo T, Sugimachi K, Yamasaki M, Tanaka F, Tachimori Y, Kajiyama Y, Natsugoe S, Fujita H, Tanaka Y, Calin G, Miyano S, Doki Y, Mori M, Mimori K

PLoS One   10 巻 ( 10 ) 頁： e0139808   2015年10月

Integrated molecular analysis of adult T cell leukemia/lymphoma

Kataoka K, Nagata Y, Kitanaka A, Shiraishi Y, Shimamura T, Yasunaga JI, Totoki Y, Chiba K, Sato-Otsubo A, Nagae G, Ishii R, Muto S, Kotani S, Watatani Y, Takeda J, Sanada M, Tanaka H, Suzuki H, Sato Y, Shiozawa Y, Yoshizato T, Yoshida K, Makishima H, Iwanaga M, Ma G, Nosaka K, Hishizawa M, Itonaga H, Imaizumi Y, Munakata W, Ogasawara H, Sato T, Sasai K, Muramoto K, Penova M, Kawaguchi T, Nakamura H, Hama N, Shide K, Kubuki Y, Hidaka T, Kameda T, Nakamaki T, Ishiyama K, Miyawaki S, Yoon SS, Tobinai K, Miyazaki Y, Takaori-Kondo A, Matsuda F, Takeuchi K, Nureki O, Aburatani H, Watanabe T, Shibata T, Matsuoka M, Miyano S, Shimoda K, Ogawa S

Nature Genetics     2015年10月

Elevated β-catenin pathway as a novel target for patients with resistance to EGF receptor targeting drugs

Nakata A, Yoshida R, Yamaguchi R, Yamauchi M, Tamada Y, Fujita A, Shimamura T, Imoto S, Higuchi T, Nomura M, Kimura T, Nokihara H, Higashiyama M, Kondoh K, Nishihara H, Tojo A, Yano S, Miyano S, Gotoh N

Scientific Reports   5 巻   頁： 13076   2015年8月

Integrated genetic and epigenetic analysis defines novel molecular subgroups in rhabdomyosarcoma

Seki M, Nishimura R, Yoshida K, Shimamura T, Shiraishi Y, Sato Y, Kato M, Chiba K, Tanaka H, Hoshino N, Nagae G, Shiozawa Y, Okuno Y, Hosoi H, Tanaka Y, Okita H, Miyachi M, Souzaki R, Taguchi T, Koh K, Hanada R, Kato K, Nomura Y, Akiyama M, Oka A, Igarashi T, Miyano S, Aburatani H, Hayashi Y, Ogawa S, Takita J

Nature Communications   6 巻   頁： 7557   2015年7月

Genomic data assimilation using a higher moment filtering technique for restoration of gene regulatory networks

Hasegawa T, Mori T, Yamaguchi R, Shimamura T, Miyano S, Imoto S, Akutsu T

  9 巻   頁： 14   2015年5月

Mutational landscape and clonal architecture in grade II and III gliomas

Suzuki H, Aoki K, Chiba K, Sato Y, Shiozawa Y, Shiraishi Y, Shimamura T, Niida A, Motomura K, Ohka F, Yamamoto T, Tanahashi K, Ranjit M, Wakabayashi T, Yoshizato T, Kataoka K, Yoshida K, Nagata Y, Sato-Otsubo A, Tanaka H, Sanada M, Kondo Y, Nakamura H, Mizoguchi M, Abe T, Muragaki Y, Watanabe R, Ito I, Miyano S, Natsume A, Ogawa S

  47 巻 ( 5 ) 頁： 458-68   2015年4月

Loss of CDCP1 expression promotes invasiveness and poor prognosis in esophageal squamous cell carcinoma

Sawada G, Takahashi Y, Niida A, Shimamura T, Kurashige J, Matsumura T, Ueo H, Uchi R, Takano Y, Ueda M, Hirata H, Sakimura S, Shinden Y, Eguchi H, Sudo T, Sugimachi K, Miyano S, Doki Y, Mori M, Mimori K

Annals of Surgical Oncology     頁： S640-7   2014年12月

Allelic imbalance at an 8q24 oncogenic SNP is involved in activating MYC in human colorectal cancer

Sugimachi K, Niida A, Yamamoto K, Shimamura T, Imoto S, Iinuma H, Shinden Y, Eguchi H, Sudo T, Watanabe M, Tanaka J, Kudo S, Hase K, Kusunoki M, Yamada K, Shimada Y, Sugihara K, Maehara Y, Miyano S, Mori M, Mimori K

    頁： S515-21   2014年10月

Robust prediction of anti-cancer drug sensitivity and sensitivity-specific biomarker

Park H, Shimamura T, Miyano S, Imoto S

PLoS One   9 巻 ( 10 ) 頁： e108990   2014年10月

Biallelic DICER1 mutations in sporadic pleuropulmonary blastoma

Seki M, Yoshida K, Shiraishi Y, Shimamura T, Sato Y, Nishimura R, Okuno Y, Chiba K, Tanaka H, Kato K, Kato M, Hanada R, Nomura Y, Park MJ, Ishida T, Oka A, Igarashi T, Miyano S, Hayashi Y, Ogawa S, Takita J

Cancer Research   74 巻 ( 10 ) 頁： 2742-9   2014年5月

Systems biology analysis of Drosophila in vivo screen data elucidates core networks for DNA damage repair in SCA1. 査読有り

Barclay SS, Tamura T, Ito H, Fujita K, Tagawa K, Shimamura T, Katsuta A, Shiwaku H, Sone M, Imoto S, Miyano S, Okazawa H

Human Molecular Genetics   23 巻 ( 5 ) 頁： 1345-64   2014年5月