Updated on 2022/05/17

写真a

 
MURATA Yuki
 
Organization
Nagoya University Hospital Gastroenterological Surgery 1 Assistant professor of hospital
Title
Assistant professor of hospital

Degree 1

  1. 学士(医学) ( 名古屋大学 ) 

Research Areas 1

  1. Life Science / Digestive surgery

Awards 1

  1. Young Investigator's Award

    2021.4   骨盤内臓全摘術後のサルコペニア-内腸骨動脈血管処理に着目して-

     More details

    Award type:Award from Japanese society, conference, symposium, etc. 

 

Papers 12

  1. 特集 直腸癌局所再発に挑む-最新の治療戦略と手術手技 総論 局所再発直腸癌の治療方針-臓器温存手術や遠隔転移併存症例の手術適応も含めて

    村田 悠記, 上原 圭, 小倉 淳司, 杉田 静紀, 渡辺 伸元, 砂川 真輝, 尾上 俊介, 宮田 一志, 山口 淳平, 水野 隆史, 伊神 剛, 國料 俊男, 横山 幸浩, 江畑 智希

    臨床外科   Vol. 77 ( 5 ) page: 514 - 519   2022.5

     More details

    Publisher:株式会社医学書院  

    DOI: 10.11477/mf.1407213704

    CiNii Research

  2. 特集 内視鏡手術からみえる新しい解剖学 II. 下部消化管 6.左側結腸癌に対する腹腔鏡下大動脈周囲リンパ節郭清

    相場 利貞, 上原 圭, 小倉 淳司, 村田 悠記, 水野 隆史, 横山 幸浩, 江畑 智希

    外科   Vol. 84 ( 5 ) page: 484 - 488   2022.5

     More details

    Publisher:南江堂  

    DOI: 10.15106/j_geka84_484

    CiNii Research

  3. Role of resection for extrahepatopulmonary metastases of colon cancer.

    Mishina T, Uehara K, Ogura A, Murata Y, Aiba T, Mizuno T, Yokoyama Y, Ebata T

    Japanese journal of clinical oncology     2022.4

     More details

    Language:English  

    DOI: 10.1093/jjco/hyac045

    PubMed

  4. Stoma creation is associated with a low incidence of midline incisional hernia after colorectal surgery: the "fighting over the fascia" theory concerning the incision and stoma hole

    Ohara Noriaki, Uehara Kay, Ogura Atsushi, Sando Masanori, Aiba Toshisada, Murata Yuki, Mizuno Takashi, Toshio Kokuryo, Yokoyama Yukihiro, Ishigaki Satoko, Li Yuanying, Yatsuya Hiroshi, Ebata Tomoki

    SURGERY TODAY     2022.1

     More details

    Language:Japanese   Publisher:Surgery Today  

    Purpose: Parastomal hernia (PH) develops more frequently than incisional hernia (IH) after colorectal surgery with stoma. This study evaluated our hypothesis that inward traction of the fascia when closing a midline incision widens the stoma hole and increases the incidence of PH. Methods: A total of 795 patients who underwent colorectal resection between 2006 and 2016 were retrospectively analyzed. The risk classification was constructed from IH risk factors extracted from the non-stoma group. Then, the classification was extrapolated to the stoma group for predicting midline IH and PH. Results: The incidence of IH was 5.3% in the stoma group and 12.5% in the non-stoma group (p = 0.005). PH developed in 19.6% of 97 patients with permanent stoma. The risk classification was able to predict PH without a significant difference but was well balanced in patients with permanent stoma; however, it failed to predict IH in the stoma group. Conclusion: The risk classification constructed from the non-stoma group was useful for predicting not midline IH but PH, suggesting that the stoma site was the most vulnerable for herniation. The “fighting over the fascia” theory between the midline incision and stoma hole may explain the causal relationship between the midline IH and PH.

    DOI: 10.1007/s00595-021-02434-y

    Web of Science

    Scopus

    PubMed

  5. Solitary Recurrent Tumor from Cecal Cancer Adjacent to the Femoral Head: A Surgical Case Report

    Mishina Takuya, Uehara Kay, Aiba Toshisada, Ogura Atsushi, Murata Yuki, Kambara Yuichi, Suzuki Yumi, Sato Yusuke, Hattori Norifumi, Nakayama Goro, Kodera Yasuhiro, Ebata Tomoki

    Nippon Daicho Komonbyo Gakkai Zasshi   Vol. 75 ( 1 ) page: 44 - 50   2022

     More details

    Language:Japanese   Publisher:The Japan Society of Coloproctology  

    <p>A 69-year-old woman visited a previous hospital with chief complaints of abdominal pain and a femoral mass. CT revealed locally advanced cecal cancer which had retroperitoneal penetration and formed a widespread abscess extending to the right femur. Systemic chemotherapy brought remarkable tumor shrinkage, therefore, conversion ileocecal resection could be performed. She received capecitabine monotherapy as an adjuvant chemotherapy for a half year.</p><p>Two and a half years after surgery, a femoral tumor was found and she was referred to our hospital. Incisional biopsy revealed that the tumor was recurrent cecal cancer. The tumor was successfully removed with combined resection of the joint capsule and femoral nerve in cooperation with orthopedic surgeons. Intraoperative radiotherapy was given around the acetabulum to improve local control. Pathological examination demonstrated that it was R1 resection at that site.</p><p>Postoperative lymphatic leakage was prolonged, therefore, a rectus abdominis musculocutaneous flap was given by plastic surgeons.</p><p>One and a half years after surgery, although meningeal dissemination without neurological symptoms developed, she remains healthy without local relapse and is receiving systemic chemotherapy.</p>

    DOI: 10.3862/jcoloproctology.75.44

    CiNii Research

  6. Local Recurrence after Abdominoperineal Resection with Vertical Rectus Abdominis Musculocutaneous Flap:A Case Report of Pelvic Exenteration with Preservation of the Flap

    Murata Yuki, Uehara Kay, Ogura Atsushi, Aiba Toshisada, Mishina Takuya, Kambara Yuichi, Suzuki Yumi, Ebata Tomoki

    Nippon Daicho Komonbyo Gakkai Zasshi   Vol. 75 ( 1 ) page: 15 - 20   2022

     More details

    Language:Japanese   Publisher:The Japan Society of Coloproctology  

    <p>A 75-year-old man underwent abdominoperineal resection (APR) and reconstruction using a right vertical rectus abdominis musculocutaneous (VRAM) flap for fistula-associated anal cancer 1 year ago. Pathological findings revealed mucinous adenocarcinoma (T4N0M0) with R1 resection. Six months after surgery, local recurrence developed and he was referred to our hospital. CT findings showed that the recurrent tumor, 30 mm in diameter, was adjacent to the right side of the prostate and the ventral side of the VRAM flap, however, there was no finding of invasion of the feeding vessels.</p><p>Total pelvic exenteration (TPE) with preservation of the VRAM flap was successfully performed. He was discharged on the 27th day after surgery and remains alive without recurrence 1 year after surgery.</p><p>The VRAM flap has been widely used in perineal reconstruction after extended pelvic surgery. In the case of local recurrence thereafter, redo surgery may be complicated, especially when the flap should be preserved. In this case, fortunately we could achieve R0 resection, however, preservation sometimes threatens curability, therefore, the indication should be carefully considered.</p>

    DOI: 10.3862/jcoloproctology.75.15

    CiNii Research

  7. 増刊号 Stepごとに要点解説 標準術式アトラス最新版-特別付録Web動画 4.大腸 直腸癌-骨盤内臓全摘術

    小倉 淳司, 上原 圭, 村田 悠記, 三品 拓也, 伊神 剛, 水野 隆史, 山口 淳平, 宮田 一志, 尾上 俊介, 渡辺 伸元, 横山 幸浩, 江畑 智希

    臨床外科   Vol. 76 ( 11 ) page: 128 - 137   2021.10

     More details

    Publisher:株式会社医学書院  

    DOI: 10.11477/mf.1407213500

    CiNii Research

  8. The carcinoembryonic antigen ratio is a potential predictor of survival in recurrent colorectal cancer

    Suzuki Yumi, Ogura Atsushi, Uehara Kay, Aiba Toshisada, Ohara Noriaki, Murata Yuki, Jinno Takanori, Mishina Takuya, Sato Yusuke, Hattori Norifumi, Nakayama Goro, Kodera Yasuhiro, Ebata Tomoki

    INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY   Vol. 26 ( 7 ) page: 1264 - 1271   2021.7

     More details

    Language:Japanese   Publisher:International Journal of Clinical Oncology  

    Background: The carcinoembryonic antigen (CEA) “value” itself is often useless in patients with a normal CEA level at initial presentation and those with tumor-irrelevant elevated CEA. Although the unified marker using CEA has been desirable for recurrent tumor staging as well as for primary tumor staging, little is known concerning its relationship with the survival of patients with recurrent colorectal cancer in particular. Methods: This retrospective historical study included patients who experienced disease relapse after curative surgery for stage I–III colorectal cancer between 2006 and 2018. A total of 129 patients with recurrent disease after curative surgery for colorectal cancer were included. We focused on the CEA “ratio” (CEA-R: the ratio of the CEA level at the time of recurrence to that measured 3 months before recurrence) and aimed to evaluate the correlation between CEA-R and survival in recurrent colorectal cancer. Results: Patients with a high CEA-R (≥ 2) exhibited significantly worse 2 year survival than those with a low CEA-R (< 2) (88.1% vs. 44.9%, P < 0.001), irrespective of the CEA value before primary resection. Multivariate analyses demonstrated that the CEA-R (HR; 3.270, 95% CI 1.646–6.497, P = 0.001) was a significant prognostic factor. Conclusion: The CEA-R is a potential marker stratifying the survival of patients with disease relapse who exhibit aggressive biology at recurrent disease foci. As a novel marker, the CEA-R would serve as a clinical guide for tailoring treatment strategies at the time of disease relapse in patients with colorectal cancer.

    DOI: 10.1007/s10147-021-01919-7

    Web of Science

    Scopus

    PubMed

  9. Transanal lateral pelvic lymph node dissection

      Vol. 76 ( 5 ) page: 596 - 602   2021.5

  10. Indications for neoadjuvant treatment based on risk factors for poor prognosis before and after neoadjuvant chemotherapy alone in patients with locally advanced rectal cancer

    Ogura Atsushi, Uehara Kay, Aiba Toshisada, Sando Masanori, Tanaka Aya, Ohara Noriaki, Murata Yuki, Sato Yusuke, Hattori Norifumi, Nakayama Goro, Ebata Tomoki, Kodera Yasuhiro, Nagino Masato

    EJSO   Vol. 47 ( 5 ) page: 1005 - 1011   2021.5

     More details

    Language:Japanese   Publisher:European Journal of Surgical Oncology  

    Introduction: The oncological benefit of neoadjuvant chemotherapy (NAC) alone for locally advanced rectal cancer (LARC) remains controversial. The aim of this study was to clarify the clinical risk factors for poor prognosis before and after NAC for decision making regarding additional treatment in patients with LARC. Materials and methods: We examined a total of 96 patients with MRI-defined poor-risk locally advanced mid-low rectal cancer treated by NAC alone between 2006 and 2018. Survival outcomes and clinical risk factors for poor prognosis before and after NAC were analyzed. Results: In the median follow-up duration after surgery of 60 months (3–120), the rates of 5-year overall survival (OS), relapse-free survival (RFS), and local recurrence (LR) were 83.6%, 78.4%, and 8.2%, respectively. In the multivariate analyses, patients with cT4 disease had a significantly higher risk of poor OS (HR; 6.10, 95% CI; 1.32–28.15, P = 0.021) than those with cT3 disease. After NAC, ycN+ was significantly associated with a higher risk of poor OS (HR; 5.92, 95% CI; 1.27–27.62, P = 0.024) and RFS (HR; 2.55, 95% CI; 1.01–6.48, P = 0.048) than ycN-. In addition, patients with CEA after NAC (post-CEA) ≥ 5 ng/ml had a significantly higher risk LR (HR; 5.63, 95% CI; 1.06–29.93, P = 0.043). Conclusion: NAC alone had an insufficient survival effect on patients with cT4 disease, ycN+, or an elevated post-CEA level. In contrast, NAC alone is a potential treatment for other patients with LARC.

    DOI: 10.1016/j.ejso.2020.10.038

    Web of Science

    Scopus

    PubMed

  11. 特集 専門医必携 新外科手術書-新しい手術手技のエッセンス IV. 大腸 5.剝離層を意識した腹腔鏡下低位前方切除術の手術手技

    小倉 淳司, 上原 圭, 相場 利貞, 村田 悠記, 江畑 智希

    外科   Vol. 83 ( 5 ) page: 506 - 512   2021.4

     More details

    Publisher:南江堂  

    DOI: 10.15106/j_geka83_506

    CiNii Research

  12. Pathological Complete Response to Second Line Chemotherapy in a Patient with Cervical Lymph Node Metastasis from Transverse Colon Cancer with RAS and BRAF V600E Mutations: A Case Report

    Murata Yuki, Uehara Kay, Aiba Toshisada, Ogura Atsushi, Fukaya Masahide, Miyata Kazushi, Tanaka Aya, Ohara Noriaki, Jinno Takanori, Ebata Tomoki

    The Japanese Journal of Gastroenterological Surgery   Vol. 54 ( 4 ) page: 278 - 284   2021.4

     More details

    Language:Japanese   Publisher:The Japanese Society of Gastroenterological Surgery  

    <p>Patients with colorectal cancer with the BRAF V600E mutation, which rarely coexists with a RAS mutation, have an extremely poor prognosis. In contrast, the outcomes of patients with a BRAF mutation and high microsatellite instability (MSI-high) have been found to be favorable. Thus, the significance of having multiple mutations remains unclear. We experienced a rare case with cervical lymph node metastasis from right-sided transverse colon cancer with RAS mutation, BRAF mutation and MSI-high, which developed 9 months after primary resection, just after completion of oxaliplatin-based 6-month adjuvant chemotherapy. As second-line chemotherapy, the patient received FOLFIRI plus aflibercept for 12 months. The tumor shrank markedly from 37 mm to 12 mm in maximum diameter and no new lesion was found; therefore, she underwent conversion surgery. Pathological findings confirmed no residual cancer cells (pathological complete response). Although the postoperative follow-up period is still <9 months, the patient has had no additional treatment after conversion surgery and is alive without recurrence. This case suggests that even in patients with metastatic colorectal cancer with the BRAF V600E mutation, aggressive surgical treatment might be an option in a situation of well-controlled systemic disease similar to that without a BRAF mutation. Further investigation of the significance of coexisting MSI-high with a BRAF mutation is required.</p>

    DOI: 10.5833/jjgs.2020.0057

    Scopus

    CiNii Research

▼display all

Presentations 4

  1. 切除不能同時性肝肺転移を有する直腸癌に対してFOLFOXIRI+bevacizumab療法で奏功が得られ二期的にR0切除し得た1例

    村田悠記

    第135回日本消化器病学会東海支部  2021.12.11  消化器内視鏡学会東海支部

     More details

    Event date: 2021.12

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:ウインクあいち   Country:Japan  

  2. 他科と連携した骨盤内臓全摘術 - 骨盤部感染の低減 /QOL 向上を目指して -

    村田悠記

    第83回日本臨床外科学会総会  2021.11.18  東京医科大学 消化器・小児外科学分野

     More details

    Event date: 2021.11

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:京王プラザホテル   Country:Japan  

  3. 骨盤側方深部郭清の精度を高める経肛門的アプローチの手術手技

    村田悠記

    第76回 日本消化器外科学会総会  2021.7.9  京都府立医科大学大学院医学研究科 消化器外科

     More details

    Event date: 2021.7

    Language:English   Presentation type:Symposium, workshop panel (public)  

    Venue:国立京都国際会館   Country:Japan  

  4. 骨盤内臓全摘術後のサルコペニア 内腸骨動脈血管処理に着目して

    村田悠記

    第121回日本外科学会  2021.4  日本外科学会

     More details

    Event date: 2021.4

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:幕張メッセ   Country:Japan