2022/05/12 更新

写真a

スギタ シズキ
杉田 静紀
SUGITA Shizuki
所属
医学部附属病院 消化器外科一 病院助教
職名
病院助教

学位 2

  1. 博士(医学) ( 2021年3月   名古屋大学 ) 

  2. 学士(医学) ( 2009年3月   名古屋市立大学 ) 

学歴 1

  1. 名古屋市立大学   医学部   医学科

    2003年4月 - 2009年3月

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    国名: 日本国

所属学協会 3

  1. 日本内視鏡外科学会

  2. 日本消化器外科学会   消化器外科専門医、指導医

  3. 日本外科学会   専門医

 

論文 3

  1. Long-term oncological outcomes of laparoscopic versus open transhiatal resection for patients with Siewert type II adenocarcinoma of the esophagogastric junction

    Sugita Shizuki, Kinoshita Takahiro, Kuwata Takeshi, Tokunaga Masanori, Kaito Akio, Watanabe Masahiro, Tonouchi Akiko, Sato Reo, Nagino Masato

    SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES   35 巻 ( 1 ) 頁: 340 - 348   2021年1月

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    記述言語:日本語   出版者・発行元:Surgical Endoscopy  

    Background: Insufficient information is available about the long-term outcomes of patients with Siewert type II adenocarcinoma of the esophagogastric junction (AEG) who undergo laparoscopic transhiatal approach (LTH). Here we evaluated the oncological safety of LTH for patients with Siewert type II AEG compared with the open transhiatal approach (OTH). Methods: Subjects included 79 patients with Siewert type II AEG who underwent gastrectomy combined with lower esophagectomy from 2008 to 2018 at our institution. Overall survival (OS), recurrence-free survival (RFS), status of adjuvant chemotherapy, late-phase complications, and recurrence patterns were compared between the OTH (n = 29) and LTH groups (n = 43). Results: The median observation periods were 60 months (6–120 months) and 36 months (1–88) for the OTH and LTH groups, respectively. The 5-year OS rates were significantly different: 74% (95% CI 71–77%) and 98% (95% CI 97–99) in the OTH and LTH groups (HR 0.10, 95% CI 0.01–0.83), respectively, though the OTH group included more patients with advanced disease. After stratification, according to pathological stage to adjust for selection bias, the 5-year OS and RFS rates were longer, but not significantly different among patients in the LTH group with pStage III (HR 0.42, 95% CI 0.05–3.47; HR 0.47, 95% CI 0.10–2.12, respectively). Recurrence patterns were similar in the both groups. Conclusions: Long-term outcomes of the LTH group were not inferior to those of the OTH group, suggesting the possibility of LTH as a treatment option for selected patients with Siewert type II AEG.

    DOI: 10.1007/s00464-020-07406-w

    Web of Science

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    PubMed

  2. Clinical significance of lymphatic invasion in the esophageal region in patients with adenocarcinoma of the esophagogastric junction

    Shizuki Sugita, Takeshi Kuwata, Masanori Tokunaga, Akio Kaito, Masahiro Watanabe, Akiko Tonouchi, Takahiro Kinoshita, Masato Nagino

    Journal of Surgical Oncology   122 巻 ( 3 ) 頁: 433 - 441   2020年5月

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    記述言語:日本語   出版者・発行元:Wiley  

    Background and Objectives: The lymphatic flow around the esophagogastric junction is complicated. Therefore, it is unclear whether lymphatic invasion in the esophageal region (eLI) and in the gastric region (gLI) in patients with adenocarcinoma of the esophagogastric junction (AEG) equally affect the incidence of lymph node metastases (LNM), and consequently, survival. Methods: We retrospectively reviewed clinicopathological data of 175 patients with AEG between January 2008 and July 2017. Risk factors for LNM and impacts of eLI or gLI on survival outcomes were investigated. Results: eLI was identified in 34% of the patients (59/175). By multivariate analysis, eLI was associated with an increased risk of both mediastinal LNM (odds ratio [OR] = 2.98, 95% confidence interval [CI]: 1.26-7.05) and abdominal LNM (OR = 5.44, 95% CI: 1.95-15.20). The 5-year overall survival for patients with eLI (53%) was significantly worse than for patients without eLI (76%) (hazard ratio = 2.45, 95% CI: 1.37-10.01). gLI was not selected in either of these analyses. Conclusions: Positive eLI was strongly associated with mediastinal and abdominal LNM and worse survival in patients with AEG compared with gLI. In the histopathological examination, it seems to make sense to assess eLI and gLI separately.

    DOI: 10.1002/jso.25964

    Web of Science

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    CiNii Research

  3. Intramucosal-lymphatic invasion has a slight impact on lymph node metastasis in patients with early gastric cancer

    Sugita Shizuki, Kinoshita Takahiro, Kuwata Takeshi, Tokunaga Masanori, Kaito Akio, Watanabe Masahiro, Tonouchi Akiko, Sato Reo, Nagino Masato

    SURGERY TODAY   50 巻 ( 5 ) 頁: 484 - 489   2020年5月

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    記述言語:日本語   出版者・発行元:Surgery Today  

    Purpose: Lymphatic invasion (LI) is associated with lymph node metastasis (LNM) and a poor prognosis in patients with early gastric cancer (EGC). Although the impact of the LI volume on LNM has been described, no reports have assessed the impact of its depth on LNM. Methods: A total of 360 EGC patients with pathologically proven LI who underwent radical gastrectomy with lymphadenectomy between January 2005 and June 2018 at our institution were extracted from our database. Patients were divided into 2 groups: the mLI group, in which LI was limited to the muscularis mucosae (n = 34); and the smLI group, in which LI reached the submucosal region (n = 326). Clinicopathological features, including the LNM incidence, were compared between the groups. Results: LNM was recognized in 3 patients (9%) in the mLI group and 101 (31%) in the smLI group (P = 0.005). In the mLI group, LNM was not recorded in any patients who met the curative criteria of ESD other than mLI. Conclusions: LI limited to the mucosal region does not seem to be a strong indicator for LNM. When pathological findings of an endoscopic submucosal dissection specimen show only mLI as a non-curative criterion, the probability of LNM may be very low.

    DOI: 10.1007/s00595-019-01913-7

    Web of Science

    Scopus

    PubMed