Updated on 2024/03/18

写真a

 
FURUKAWA Katsuya
 
Organization
Nagoya University Hospital Center for Postgraduate Clinical Training and Career Development Assistant professor of hospital
Title
Assistant professor of hospital

Degree 1

  1. bachelor （ 2011.3   Nara Medical University ） 

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Papers 10

  1. Development and Efficacy of a Novel Bromodomain and Extraterminal Domain Degrader K-256 in MYC/BCL2-Related Lymphoma

    Furukawa, K; Shimada, K; Esaki, M; Tanaka, K; Yamamoto, K; Mori, K; Kiyoi, H

    BLOOD   Vol. 142   2023.11

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  2. Clinicopathological characteristics associated with the engraftment of patient lymphoma cells in NOG mice Invited Reviewed

    Sahashi S, Shimada K, Takagi Y, Aoki T, Kunou S, Sakamoto A, Murase A, Furukawa K, Kagaya Y, Yamaga Y, Takai M, Tokuyama K, Shimada S, Nakamura S, Kiyoi H.

    Int J Hematol   Vol. 118 ( 2 ) page： 221 - 230   2023.8

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    Language：English  

  3. Cellular kinetics and outcome of tisagenlecleucel for diffuse large B-cell lymphoma Reviewed

    HANAJIRI Ryo, FURUKAWA Katsuya, NAKASHIMA Marie, USHIJIMA Yoko, SHIMADA Kazuyuki, ISHIKAWA Yuichi, TERAKURA Seitaro, MURATA Makoto, KIYOI Hitoshi

    Rinsho Ketsueki   Vol. 64 ( 3 ) page： 167 - 174   2023

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    Language：Japanese   Publisher：The Japanese Society of Hematology  

    <p>CD19-targeted chimeric antigen receptor T-cell (CAR-T) therapy has shown promise as treatment of relapsed or refractory B-cell malignancies. However, the clinical utility of early CAR-T monitoring within 1 month after infusion has not been elucidated. In this study, we quantitatively measured CAR-T kinetics in peripheral blood on days 2, 4, 7, 9, 11, 14, 21, and 28 post-infusion using flow cytometry and quantitative polymerase chain reaction in 13 patients with relapsed refractory diffuse large B-cell lymphoma (DLBCL) treated with tisagenlecleucel (tisa-cel). No relationships were identified between bulk CAR-T kinetics and treatment outcomes. Interestingly, the magnitude of CD4<sup>+</sup> CAR-T expansion was higher in responders than in nonresponders, while CD8<sup>+</sup> CAR-T expansion was minimal in responders. Additionally, CAR-T proliferation was more pronounced in patients with cytokine release syndrome. Our results suggest that CD4<sup>+</sup> CAR-T cellular kinetics within 1 month after CAR-T infusion may predict its efficacy after tisa-cel therapy in adult patients with DLBCL.</p>

    DOI： 10.11406/rinketsu.64.167

    PubMed

    CiNii Research

  4. Mantle cell lymphoma with aseptic meningitis mimicking hydrocephalus on brain imaging Reviewed

    Satoshi Samizo, Katsuya Furukawa, Hiroyuki Umegaki

    Nagoya J Med Sci.   Vol. 84 ( 2 ) page： 470 - 476   2022.5

  5. CD19-positive lymphocyte count is critical for acquisition of anti-SARS-CoV-2 IgG after vaccination in B-cell lymphoma. Reviewed

    Okamoto A, Fujigaki H, Iriyama C, Goto N, Yamamoto H, Mihara K, Inaguma Y, Miura Y, Furukawa K, Yamamoto Y, Akatsuka Y, Kasahara S, Miyao K, Tokuda M, Sato S, Mizutani Y, Osawa M, Hattori K, Iba S, Kajiya R, Okamoto M, Saito K, Tomita A

    Blood advances     2022.1

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    Language：English  

    DOI： 10.1182/bloodadvances.2021006302

    PubMed

  6. Follicular T-cell lymphoma mimicking lymphocyte-rich classic Hodgkin lymphoma: a case report of a diagnostic pitfall

    Sakakibara Ayako, Suzuki Yuka, Kato Harumi, Yamamoto Kazuhito, Sakata-Yanagimoto Mamiko, Ishikawa Yuichi, Furukawa Katsuya, Shimada Kazuyuki, Kohno Kei, Nakamura Shigeo, Satou Akira, Kato Seiichi

    Journal of Clinical and Experimental Hematopathology   Vol. 61 ( 2 ) page： 97 - 101   2021

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    Language：English   Publisher：The Japanese Society for Lymphoreticular Tissue Research  

    <p>Follicular T-cell lymphoma (FTCL), one of the nodal T-cell lymphomas with T follicular helper (T<sub><sup>FH</sup></sub>) phenotype, is an uncommon disease. The diagnosis of FTCL is challenging on the distinction from the morphological mimics mostly exemplified by follicular lymphoma. Here, we described a case of FTCL that mimicked lymphocyte-rich classic Hodgkin lymphoma (LRCHL). A 47-year-old male presented with cervical lymphadenopathy. The biopsy specimen demonstrated nodular lymphoid proliferation, which included scattered CD30+ CD15- CD20- PAX5 weakly+ Hodgkin and Reed-Sternberg (HRS)-like cells and a rich distribution of CD3+ CD4+ PD1+ T-cells. Epstein Barr virus was not detected in HRS-like cells, but it was detected in a small proportion of the scattered lymphocytes. The large cells were also negative for programmed cell death ligand 1, which appeared to be coincidental as described in our previous report of LRCHL. However, flow cytometry showed a CD3- CD4+ T-cell population that constituted 37.4% of all gated lymphocytes. A PCR analysis showed a clonal T-cell receptor-gamma gene rearrangement, but not a clonal immunoglobulin heavy chain gene rearrangement, and showed <i>RHOA</i> G17V mutation. The constellation of these findings led us to revise the diagnosis to FTCL. This result indicated that our case belonged to a relatively indolent subgroup of nodal peripheral T-cell lymphoma of T<sub><sup>FH</sup></sub> phenotype, which affects patients ≤60 years old, recently proposed by our group. This case report expands our understanding of the morphologic spectrum of FTCL and its clinicopathologic significance.</p>

    DOI： 10.3960/jslrt.20052

    Web of Science

    PubMed

    CiNii Research

  7. Primary cutaneous NK/T-cell lymphoma of nasal type: an age-related lymphoproliferative disease? Reviewed

    Chun-Chieh Wu, Emiko Takahashi, Naoko Asano, Tomoko Miyata-Takata, Katsuyoshi Takata, Katsuya Furukawa, Ahmed Ali Elsayed, Lei-Ming Hu, Akira Satou MD, Kei Kohno, Hiroshi Kosugi, Kenichi Ohashi, Tomohiro Kinoshita, Shigeo Nakamura, Seiichi Kato.

    Human Pathology   Vol. 68   page： 61 - 8   2017.10

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    Language：English  

    DOI： 10.1016/j.humpath.2017.08.025

  8. Welder's pulmonary hemosiderosis associated with systemic iron overload following exacerbation of acute adult T-cell leukemia/lymphoma. Reviewed

    J Clin Exp Hematop   Vol. 57 ( 2 ) page： 74 - 8   2017.10

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  9. Clinicopathological analysis of 12 patients with Epstein-Barr virus-positive primary gastrointestinal T/NK-cell lymphoma. (EBV+ GITNKL) Reviewed

    Lei-Ming Hu, Katsuyoshi Takata, Tomoko Miyata-Takata, Naoko Asano, Emiko Takahashi, Katsuya Furukawa, Hiroaki Miyoshi, Akira Satou, Kei Kohno, Hiroshi Kosugi, Tomohiro Kinoshita, Yoshiki Hirooka, Hidemi Goto, Shigeo Nakamura, Seiichi Kato.

    Histopathology   Vol. 70 ( 7 ) page： 1052 - 63   2017.6

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  10. GM-CSF Autoantibodypositive Pulmonary Alveolar Proteinosis with Simultaneous Myeloproliferative Neoplasm. Reviewed

    Naoto Imoto, Nakashima Harunori, Katsuya Furukawa, Naoyuki Tange, Atsushi Murase, Masaya Hayakawa, Masatoshi Ichihara, Yosuke Iwata, Hiroshi Kosugi.

    Intern Med.   Vol. 56 ( 4 ) page： 435 - 9   2017.2

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Books 4

  1. 再発および治療抵抗性造血器腫瘍の治療戦略

    古川勝也, 島田和之（再発・難治性びまん性大細胞型B細胞リンパ腫に対する治療）

    科学評論社  2021.8 

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    Total pages：212-7  

  2. 病期とくすり2021 基礎と実践Expert’s Guide

    古川勝也, 島田和之, 清井仁（悪性リンパ腫）

    南山堂  2021 

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    Responsible for pages：1526-35  

  3. リンパ系腫瘍の治療開発で明らかになったことと今後の課題

    古川勝也, 山本一仁（未治療マントル細胞リンパ腫に対する標準導入療法と今後の課題）

    科学評論社  2018.6 

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    Responsible for pages：732-7  

  4. 診断と治療のABC [133] 悪性リンパ腫

    古川勝也, 山本一仁（（第4章）管理・治療組織型別の経過・予後）

    最新医学社  2018.4 

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