Faculty Profiles - FURUKAWA Katsuya

写真a

FURUKAWA Katsuya

Organization

Nagoya University Hospital Center for Postgraduate Clinical Training and Career Development Assistant professor of hospital

Degree 1

bachelor （ 2011.3 Nara Medical University ）

To the head of Degree.▲

Papers 12

Simple and early prediction of severe CAR-T-related adverse events after Axi-cel infusion by initial high fever. Invited Reviewed

Wakabayashi H, Terakura S, Ishigiwa K, Ohara F, Hirano S, Yokota H, Kuwano S, Furukawa K, Shimada K, Sato T, Hanajiri R, Kiyoi H.

Int J Hematol. 2025.2

　More details

DOI： 10.1007/s12185-025-03957-7.
Spheroid culture to select theoretical therapeutic drugs in intravascular large B-cell lymphoma. Reviewed

Takai M, Shimada K, Furukawa K, Yamaga Y, Yoshiyama S, Kagaya Y, Suzuki T, Hayashi K, Shimada S, Karube K, Kiyoi H.

Cancer Sci. Vol. 116 ( 1 ) page： 214 - 225 2025.1

　More details

Language：English
Development and Efficacy of a Novel Bromodomain and Extraterminal Domain Degrader K-256 in MYC/BCL2-Related Lymphoma

Furukawa, K; Shimada, K; Esaki, M; Tanaka, K; Yamamoto, K; Mori, K; Kiyoi, H

BLOOD Vol. 142 2023.11

　More details

DOI： 10.1182/blood-2023-179334

Web of Science
Clinicopathological characteristics associated with the engraftment of patient lymphoma cells in NOG mice Invited Reviewed

Sahashi S, Shimada K, Takagi Y, Aoki T, Kunou S, Sakamoto A, Murase A, Furukawa K, Kagaya Y, Yamaga Y, Takai M, Tokuyama K, Shimada S, Nakamura S, Kiyoi H.

Int J Hematol Vol. 118 ( 2 ) page： 221 - 230 2023.8

　More details

Language：English
Cellular kinetics and outcome of tisagenlecleucel for diffuse large B-cell lymphoma Reviewed

HANAJIRI Ryo, FURUKAWA Katsuya, NAKASHIMA Marie, USHIJIMA Yoko, SHIMADA Kazuyuki, ISHIKAWA Yuichi, TERAKURA Seitaro, MURATA Makoto, KIYOI Hitoshi

Rinsho Ketsueki Vol. 64 ( 3 ) page： 167 - 174 2023

　More details

Language：Japanese Publisher：The Japanese Society of Hematology

CD19-targeted chimeric antigen receptor T-cell (CAR-T) therapy has shown promise as treatment of relapsed or refractory B-cell malignancies. However, the clinical utility of early CAR-T monitoring within 1 month after infusion has not been elucidated. In this study, we quantitatively measured CAR-T kinetics in peripheral blood on days 2, 4, 7, 9, 11, 14, 21, and 28 post-infusion using flow cytometry and quantitative polymerase chain reaction in 13 patients with relapsed refractory diffuse large B-cell lymphoma (DLBCL) treated with tisagenlecleucel (tisa-cel). No relationships were identified between bulk CAR-T kinetics and treatment outcomes. Interestingly, the magnitude of CD4+ CAR-T expansion was higher in responders than in nonresponders, while CD8+ CAR-T expansion was minimal in responders. Additionally, CAR-T proliferation was more pronounced in patients with cytokine release syndrome. Our results suggest that CD4+ CAR-T cellular kinetics within 1 month after CAR-T infusion may predict its efficacy after tisa-cel therapy in adult patients with DLBCL.

DOI： 10.11406/rinketsu.64.167

PubMed

CiNii Research
Mantle cell lymphoma with aseptic meningitis mimicking hydrocephalus on brain imaging Reviewed

Satoshi Samizo, Katsuya Furukawa, Hiroyuki Umegaki

Nagoya J Med Sci. Vol. 84 ( 2 ) page： 470 - 476 2022.5
CD19-positive lymphocyte count is critical for acquisition of anti-SARS-CoV-2 IgG after vaccination in B-cell lymphoma. Reviewed

Okamoto A, Fujigaki H, Iriyama C, Goto N, Yamamoto H, Mihara K, Inaguma Y, Miura Y, Furukawa K, Yamamoto Y, Akatsuka Y, Kasahara S, Miyao K, Tokuda M, Sato S, Mizutani Y, Osawa M, Hattori K, Iba S, Kajiya R, Okamoto M, Saito K, Tomita A

Blood advances 2022.1

　More details

Language：English

DOI： 10.1182/bloodadvances.2021006302

PubMed
Follicular T-cell lymphoma mimicking lymphocyte-rich classic Hodgkin lymphoma: a case report of a diagnostic pitfall

Sakakibara Ayako, Suzuki Yuka, Kato Harumi, Yamamoto Kazuhito, Sakata-Yanagimoto Mamiko, Ishikawa Yuichi, Furukawa Katsuya, Shimada Kazuyuki, Kohno Kei, Nakamura Shigeo, Satou Akira, Kato Seiichi

Journal of Clinical and Experimental Hematopathology Vol. 61 ( 2 ) page： 97 - 101 2021

　More details

Language：English Publisher：The Japanese Society for Lymphoreticular Tissue Research

Follicular T-cell lymphoma (FTCL), one of the nodal T-cell lymphomas with T follicular helper (TFH) phenotype, is an uncommon disease. The diagnosis of FTCL is challenging on the distinction from the morphological mimics mostly exemplified by follicular lymphoma. Here, we described a case of FTCL that mimicked lymphocyte-rich classic Hodgkin lymphoma (LRCHL). A 47-year-old male presented with cervical lymphadenopathy. The biopsy specimen demonstrated nodular lymphoid proliferation, which included scattered CD30+ CD15- CD20- PAX5 weakly+ Hodgkin and Reed-Sternberg (HRS)-like cells and a rich distribution of CD3+ CD4+ PD1+ T-cells. Epstein Barr virus was not detected in HRS-like cells, but it was detected in a small proportion of the scattered lymphocytes. The large cells were also negative for programmed cell death ligand 1, which appeared to be coincidental as described in our previous report of LRCHL. However, flow cytometry showed a CD3- CD4+ T-cell population that constituted 37.4% of all gated lymphocytes. A PCR analysis showed a clonal T-cell receptor-gamma gene rearrangement, but not a clonal immunoglobulin heavy chain gene rearrangement, and showed RHOA G17V mutation. The constellation of these findings led us to revise the diagnosis to FTCL. This result indicated that our case belonged to a relatively indolent subgroup of nodal peripheral T-cell lymphoma of TFH phenotype, which affects patients ≤60 years old, recently proposed by our group. This case report expands our understanding of the morphologic spectrum of FTCL and its clinicopathologic significance.

DOI： 10.3960/jslrt.20052

Web of Science

PubMed

CiNii Research
Primary cutaneous NK/T-cell lymphoma of nasal type: an age-related lymphoproliferative disease? Reviewed

Chun-Chieh Wu, Emiko Takahashi, Naoko Asano, Tomoko Miyata-Takata, Katsuyoshi Takata, Katsuya Furukawa, Ahmed Ali Elsayed, Lei-Ming Hu, Akira Satou MD, Kei Kohno, Hiroshi Kosugi, Kenichi Ohashi, Tomohiro Kinoshita, Shigeo Nakamura, Seiichi Kato.

Human Pathology Vol. 68 page： 61 - 8 2017.10

　More details

Language：English

DOI： 10.1016/j.humpath.2017.08.025
Welder's pulmonary hemosiderosis associated with systemic iron overload following exacerbation of acute adult T-cell leukemia/lymphoma. Reviewed

J Clin Exp Hematop Vol. 57 ( 2 ) page： 74 - 8 2017.10

　More details

DOI： 10.3960/jslrt.17024
Clinicopathological analysis of 12 patients with Epstein-Barr virus-positive primary gastrointestinal T/NK-cell lymphoma. (EBV+ GITNKL) Reviewed

Lei-Ming Hu, Katsuyoshi Takata, Tomoko Miyata-Takata, Naoko Asano, Emiko Takahashi, Katsuya Furukawa, Hiroaki Miyoshi, Akira Satou, Kei Kohno, Hiroshi Kosugi, Tomohiro Kinoshita, Yoshiki Hirooka, Hidemi Goto, Shigeo Nakamura, Seiichi Kato.

Histopathology Vol. 70 ( 7 ) page： 1052 - 63 2017.6

　More details

DOI： 10.1111/his.13172
GM-CSF Autoantibodypositive Pulmonary Alveolar Proteinosis with Simultaneous Myeloproliferative Neoplasm. Reviewed

Naoto Imoto, Nakashima Harunori, Katsuya Furukawa, Naoyuki Tange, Atsushi Murase, Masaya Hayakawa, Masatoshi Ichihara, Yosuke Iwata, Hiroshi Kosugi.

Intern Med. Vol. 56 ( 4 ) page： 435 - 9 2017.2

▼display all

To the head of Papers.▲

Books 4

再発および治療抵抗性造血器腫瘍の治療戦略

古川勝也, 島田和之（再発・難治性びまん性大細胞型B細胞リンパ腫に対する治療）

科学評論社 2021.8

　More details

Total pages：212-7
病期とくすり2021 基礎と実践Expert’s Guide

古川勝也, 島田和之, 清井仁（悪性リンパ腫）

南山堂 2021

　More details

Responsible for pages：1526-35
リンパ系腫瘍の治療開発で明らかになったことと今後の課題

古川勝也, 山本一仁（未治療マントル細胞リンパ腫に対する標準導入療法と今後の課題）

科学評論社 2018.6

　More details

Responsible for pages：732-7
診断と治療のABC [133] 悪性リンパ腫

古川勝也, 山本一仁（（第4章）管理・治療組織型別の経過・予後）

最新医学社 2018.4

To the head of Books.▲

Presentations 3

MYC/BCL2関連リンパ腫に対する新規BET分解薬（K-256）の有効性

古川勝也

第86回日本血液学会学術集会 2024.10.11

　More details

Event date： 2024.10

Language：Japanese Presentation type：Poster presentation

Venue：京都 Country：Japan
Development and Efficacy of a Novel Bromodomain and Extraterminal Domain Degrader K-256 in MYC/BCL2-Related Lymphoma International conference

2023.12.11

　More details

Event date： 2023.12

Language：English Presentation type：Poster presentation

Venue：サンティエゴ Country：United States
CNS浸潤を伴う初発DLBCLに対してHD-MTX併用R-CHOP療法を施行した3例

古川勝也

第12回日本血液学会東海地方会 2023.5.21

　More details

Event date： 2023.5

Language：Japanese

Venue：愛知県 Country：Japan

To the head of Presentations.▲