Updated on 2024/03/12

写真a

 
YAMAMOTO Kenta
 
Organization
Nagoya University Hospital Diagnostic and Therapeutic Endoscopy Assistant professor of hospital
Title
Assistant professor of hospital
External link

Degree 1

  1. 博士(医学) ( 2019.5   名古屋大学 ) 

Research Interests 4

  1. Hepatocellular carcinoma

  2. Gastroenterology

  3. Liver

  4. Microbiome

Research Areas 3

  1. Life Science / Gastroenterology  / Hepatology

  2. Others / Others  / Microbiome

  3. Life Science / Gastroenterology

Current Research Project and SDGs 1

  1. 腸内細菌叢を介した新たな治療開発による健康への貢献

Education 2

  1. Nagoya University   Graduate School, Division of Medical Sciences

    2014.4 - 2019.3

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    Country: Japan

  2. Hamamatsu University School of Medicine   Faculty of Medicine

    2002.4 - 2008.3

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    Country: Japan

Professional Memberships 6

  1. the Japan Gastroenterological Endoscopy Society

  2. the Japanese Society of Gastrointestinal Cancer Screening

  3. the Japan Society of Ultrasonics in Medicine

  4. The Japanese Society of Gastroenterology

  5. the Japan Society of Hepatology

  6. Japanese Society of Internal Medicine

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Awards 2

  1. JSGE-UEG Rising Stars

    2021.10   The Japanese Society of Gastroenterology   Focusing on the oral origin bacteria in the gut

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    Award type:Award from international society, conference, symposium, etc.  Country:Austria

  2. Freiburg Rising Stars Academy

    2021.10   the University of Freiburg  

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    Country:Germany

 

Papers 70

  1. Characteristics of microbiomes of the saliva, duodenal bulb, and descending portion of superficial nonampullary duodenal epithelial tumors Reviewed

    Shibata H, Yamamoto K, Hirose T, Furune S, Kakushima N, Furukawa K, Nakamura M, Honda T, Fujishiro M, Kawashima H.

    Dig Liver Dis   Vol. 26 ( 24 )   2024.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.dld.2024.01.212

  2. Effects of 1-kestose on microbiome changes caused by vonoprazan: a randomized, double-blind, placebo-controlled pilot study Reviewed

    Furune S, Suzuki T, Honda T, Yamamoto K, Furukawa K, Nakamura M, Ishigami M, Kinoshita F, Kadota Y, Tochio T, Shimomura Y, Hirooka Y, Fujishiro M, Kawashima H.

    J Gastroenterol Hepatol   Vol. 39 ( 3 ) page: 480 - 488   2023.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/jgh.16445

  3. Monoclonal Antibody Against Mature Interleukin-18 Ameliorates Colitis in Mice and Improves Epithelial Barrier Function Reviewed

    Ikegami S, Maeda K, Urano T, Mu J, Nakamura M, Yamamura T, Sawada T, Ishikawa E, Yamamoto K, Muto H, Oishi A, Iida T, Mizutani Y, Ishikawa T, Kakushima N, Furukawa K, Ohno E, Honda T, Ishigami M, Kawashima H.

    Inflamm Bowel Dis     2023.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1093/ibd/izad292

  4. Impact of elobixibat on liver tumors, microbiome, and bile acid levels in a mouse model of nonalcoholic steatohepatitis Reviewed

    Sugiyama Y, Yamamoto K, Honda T, Kato A, Muto H, Yokoyama S, Ito T, Imai N, Ishizu Y, Nakamura M, Asano T, Enomoto A, Zaitsu K, Ishigami M, Fujishiro M, Kawashima H.

    Hepatol Internatoinal     2023.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s12072-023-10581-2

  5. Efficacy of 1-kestose supplementation in patients with mild to moderate ulcerative colitis: A randomised, double-blind, placebo-controlled pilot study Reviewed

    Ikegami S, Nakamura M, Honda T, Yamamura T, Maeda K, Sawada T, Ishikawa E, Yamamoto K, Furune S, Ishikawa T, Furukawa K, Ohno E, Ishigami M, Kinoshita F, Kadota Y, Tochio T, Shimomura Y, Hirooka Y, Kawashima H.

    Aliment Pharmacol Ther   Vol. 57 ( 11 ) page: 1249 - 1257   2023.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/apt.17387

  6. Differences in the Intestinal Microbiome Associated with Diarrhea during Lenvatinib Treatment for Hepatocellular Carcinoma Reviewed

    Inukai Y, Yamamoto K, Honda T, Ito T, Imai N, Ishizu Y, Nakamura M, Kawashima H, Ishigami M.

      Vol. 41 ( 1 ) page: 138 - 147   2023

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1159/000524298

  7. Fecal microbiota transplantation in the treatment of irritable bowel syndrome: a single-center prospective study in Japan Reviewed

    Hamazaki M, Sawada T, Yamamura T, Maeda K, Mizutani Y, Ishikawa E, Furune S, Yamamoto K, Ishikawa T, Kakushima N, Furukawa K, Ohno E, Honda T, Kawashima H, Ishigami M, Nakamura M, Fujishiro M.

      Vol. 22 ( 1 ) page: 342 - -   2022.7

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1186/s12876-022-02408-5

  8. Changes in the gut microbiome in relation to the degree of gastric mucosal atrophy before and after Helicobacter pylori eradication Reviewed

    Furune S, Yamamoto K, Honda T, Fujiyoshi T, Kakushima N, Furukawa K, Ohno E, Nakamura M, Miyahara R, Kawashima H, Ishigami M, Hirooka Y, Fujishiro M.

    Scand J Gastroenterol   Vol. 57 ( 3 ) page: 266 - 273   2022.5

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1080/00365521.2021.2005135

  9. Patients with low muscle mass have characteristic microbiome with low potential for amino acid synthesis in chronic liver disease Reviewed

    Yamamoto K, Ishizu Y, Honda T, Ito T, Imai N, Nakamura M, Kawashima H, Kitaura Y, Ishigami M, Fujishiro M.

    Sci Rep   Vol. 12 ( 1 ) page: 3674   2022.3

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41598-022-07810-3

  10. Preliminary Comparison of Endoscopic Brush and Net Catheters as the Sampling Tool to Analyze the Intestinal Mucus in the Rectum with Ulcerative Colitis Patients Reviewed

    Nakamura M, Maeda K, Yamamoto K, Yamamura T, Sawada T, Ishikawa E, Kakushima N, Furukawa K, Iida T, Mizutani Y, Ishikawa T, Ohno E, Honda T, Ishigami M, Kawashima H.

    Digestion   Vol. 103 ( 3 ) page: 232 - 243   2022.2

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1159/000521929

  11. Network Analysis of Gut Microbiota Including Fusobacterium and Oral Origin Bacteria and Their Distribution on Tumor Surface, Normal Mucosa, and in Feces in Patients with Colorectal Cancer Reviewed

    Ohashi A, Yamamura T, Nakamura M, Maeda K, Sawada T, Ishikawa E, Yamamoto K, Ishikawa T, Kakushima N, Furukawa K, Ohno E, Honda T, Kawashima H, Ishigami M, Fujishiro M.

      Vol. 103 ( 6 ) page: 451 - 461   2022

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1159/000527170

  12. Changes in the gut microbiota after hepatitis C virus eradication Reviewed

    Honda T, Ishigami M, Yamamoto K, Takeyama T, Ito T, Ishizu Y, Kuzuya T, Nakamura M, Kawashima H, Miyahara R, Ishikawa T, Hirooka Y, Fujishiro M.

    Sci Rep   Vol. 11 ( 1 ) page: 23568   2021.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41598-021-03009-0

  13. Measurement of fasting breath hydrogen concentration as a simple diagnostic method for pancreatic exocrine insufficiency Reviewed

    Uetsuki K, Kawashima H, Ohno E, Ishikawa T, Iida T, Yamamoto K, Furukawa K, Nakamura M, Honda T, Ishigami M, Hirooka Y, Fujishiro M

    BMC gastroenterology   Vol. 21 ( 1 ) page: 211   2021.5

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1186/s12876-021-01776-8

  14. Microbiome, fibrosis and tumor networks in a non-alcoholic steatohepatitis model of a choline-deficient high-fat diet using diethylnitrosamine Reviewed

    Kenta Yamamoto Takashi Honda Shinya Yokoyama Lingyun Asuka Kato Takanori Ito Yoji Ishizu Teiji Kuzuya Masanao Nakamura Hiroki Kawashima Masatoshi Ishigami Noriko M.Tsuji Mitsuhiro Fujishiro

    Digestive and Liver Disease   Vol. 53 ( 11 ) page: 1443 - 1450   2021

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.dld.2021.02.013

  15. Conditioned medium from stem cells derived from human exfoliated deciduous teeth ameliorates NASH via the Gut-Liver axis. Reviewed

    Muto H, Ito T, Tanaka T, Yokoyama S, Yamamoto K, Imai N, Ishizu Y, Maeda K, Honda T, Ishikawa T, Kato A, Ohshiro T, Kano F, Yamamoto A, Sakai K, Hibi H, Ishigami M, Fujishiro M

    Scientific reports.   Vol. 11 ( 1 ) page: 18778   2021

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    Language:English   Publishing type:Research paper (scientific journal)  

  16. The microbiome can predict mucosal healing in small intestine in patients with Crohn’s disease Reviewed

    Shun Hattori, Masanao Nakamura, Takeshi Yamamura, Keiko Maeda, Tsunaki Sawada, Yasuyuki Mizutani, Kenta Yamamoto, Takuya Ishikawa, Kazuhiro Furukawa, Eizaburo Ohno, Takashi Honda, Hiroki Kawashima, Masatoshi Ishigami, Yoshiki Hirooka Mitsuhiro Fujishiro

    Journal of gastroenterology   Vol. 55 ( 12 ) page: 1138 - 1149   2020.12

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    Language:English   Publishing type:Research paper (scientific journal)  

  17. The relationship between oral-origin bacteria in the fecal microbiome and albumin-bilirubin grade in patients with hepatitis C Reviewed

    Kenta Yamamoto , Takashi Honda , Takanori Ito , Yoji Ishizu , Teiji Kuzuya , Masanao Nakamura , Ryoji Miyahara , Hiroki Kawashima , Masatoshi Ishigami , Mitsuhiro Fujishiro

    Journal of Gastroenterology and Hepatology   Vol. 36 ( 3 ) page: 790 - 799   2020.8

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/jgh.15206

  18. Relationship between Adverse Events and Microbiomes in Advanced Hepatocellular Carcinoma Patients Treated with Sorafenib Reviewed

    Yamamoto, Kenta, Teiji Kuzuya, Takashi Honda, Takanori Ito, Yoji Ishizu, Masanao Nakamura, Ryoji Miyahara, Hiroki Kawashima, Masatoshi Ishigami, and Mitsuhiro Fujishiro

    Anticancer Research   Vol. 40 ( 2 ) page: 665–76   2020

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  19. Microbiota Profile Is Different for Early and Invasive Colorectal Cancer and Is Consistent throughout the Colon. Reviewed

    Zorron Cheng Tao Pu, Leonardo, Kenta Yamamoto, Takashi Honda, Masanao Nakamura, Takeshi Yamamura, Shun Hattori, Alastair D. Burt, Rajvinder Singh, Yoshiki Hirooka, and Mitsuhiro Fujishiro.

    Journal of Gastroenterology and Hepatology   Vol. 35 ( 3 ) page: 433–37   2020

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    Language:English   Publishing type:Research paper (scientific journal)  

  20. Influence of Proton Pump Inhibitors on Microbiota in Chronic Liver Disease Patients. Reviewed

    Yamamoto, Kenta, Masatoshi Ishigami, Takashi Honda, Tomoaki Takeyama, Takanori Ito, Yoji Ishizu, Teiji Kuzuya, Kazuhiko Hayashi, Hidemi Goto, and Yoshiki Hirooka.

    Hepatology International   Vol. 13 ( 2 ) page: 234–44   2019

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  21. A new criterion including the aspartate aminotransferase-to-platelet ratio index and liver and spleen stiffness to rule out varices needing treatment in children with biliary atresia: Modification of the Baveno VII criteria Reviewed

    Yokoyama S, Ishizu Y, Honda T, Imai N, Ito T, Yamamoto K, Muto H, Shirota C, Tainaka T, Sumida W, Makita S, Takada S, Nakagawa Y, Maeda T, Nakamura M, Ishigami M, Uchida H, Kawashima H.

    Hepatol Res     2023.10

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/hepr.13976

  22. Clinical course and prognosis of patients with hepatocellular carcinoma and haemophilia Reviewed

    Matsuda N, Imai N, Yokoyama S, Yamamoto K, Ito T, Ishizu Y, Honda T, Okamoto S, Kanematsu T, Suzuki N, Matsushita T, Ishigami M, Kawashima H.

    European Journal of Gastroenterology and Hepatology   Vol. 35 ( 10 ) page: 1211 - 1215   2023.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1097/MEG.0000000000002628

  23. Pretreatment Proteinuria Predicts the Prognosis of Patients Receiving Systemic Therapy for Unresectable Hepatocellular Carcinoma Reviewed

    Mizuno K, Imai N, Yamamoto T, Yokoyama S, Yamamoto K, Ito T, Ishizu Y, Honda T, Kuzuya T, Ishigami M, Kawashima H.

    Cancers   Vol. 21 ( 15 ) page: 2853   2023.6

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/cancers15102853

  24. Abdominal pain accompanied by elevated serum inflammatory markers and biliary enzymes for diagnosing immune checkpoint inhibitor-induced sclerosing cholangitis Reviewed

    Yamamoto T, Mizuno K, Ito T, Yokoyama S, Yamamoto K, Imai N, Ishizu Y, Honda T, Ishikawa T, Kanamori A, Yasuda S, Toyoda H, Yokota K, Hase T, Nishio N, Maeda O, Ishii M, Sone M, Ando Y, Akiyama M, Ishigami M, Kawashima H.

    Investigational New Drugs   Vol. 41 ( 3 ) page: 512 - 521   2023.5

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s10637-023-01366-3

  25. Successful Treatment with Steroids in a Patient with Vanishing Bile Duct Syndrome and Acute Tubular Necrosis Reviewed

    Mizuno F, Imai N, Yasuda K, Yokoyama S, Yamamoto K, Ito T, Ishizu Y, Honda T, Ishigami M, Kawashima H.

    Internal Medicine     2023.5

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.2169/internalmedicine.1826-23

  26. Distinct features of two lipid droplets types in cell nuclei from patients with liver diseases Reviewed

    Imai N, Ohsaki Y, Cheng J, Zhang J, Mizuno F, Tanaka T, Yokoyama S, Yamamoto K, Ito T, Ishizu Y, Honda T, Ishigami M, Wake H, Kawashima H.

    Scientific Reports   Vol. 26 ( 13 ) page: 6851   2023.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41598-023-33977-4

  27. Proteomic Analysis Reveals Changes in Tight Junctions in the Small Intestinal Epithelium of Mice Fed a High-Fat Diet Reviewed

    Muto H, Honda T, Tanaka T, Yokoyama S, Yamamoto K, Ito T, Imai N, Ishizu Y, Maeda K, Ishikawa T, Adachi S, Sato C, Tsuji NM, Ishigami M, Fujishiro M, Kawashima H.

    Nutrients   Vol. 19 ( 15 ) page: 1473   2023.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/nu15061473

  28. Clustering using unsupervised machine learning to stratify the risk of immune-related liver injury Reviewed

    Yamamoto T, Morooka H, Ito T, Ishigami M, Mizuno K, Yokoyama S, Yamamoto K, Imai N, Ishizu Y, Honda T, Yokota K, Hase T, Maeda O, Hashimoto N, Ando Y, Akiyama M, Kawashima H.

      Vol. 38 ( 2 ) page: 251 - 258   2023.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/jgh.16038

  29. Endoscopic injection sclerotherapy with polidocanol for cardiac varices in children and adolescents Reviewed

    Yokoyama S, Ishizu Y, Honda T, Imai N, Ito T, Yamamoto K, Hinoki A, Sumida W, Shirota C, Tainaka T, Makita S, Yokota K, Uchida H, Ishigami M.

      Vol. 30 ( 2 ) page: 109 - 112   2023.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.arcped.2022.11.016

  30. Significance of pretreatment alpha-fetoprotein in patients with compensated severe fibrosis after hepatitis C viral eradication Reviewed

    Ishigami M, Honda T, Ishizu Y, Imai N, Ito T, Yamamoto K, Kawashima H.

    J Hepatobiliary Pancreat Sci   Vol. 30 ( 6 ) page: 834 - 842   2023.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/jhbp.1309

  31. Astaxanthin Attenuates Nonalcoholic Steatohepatitis with Downregulation of Osteoprotegerin in Ovariectomized Mice Fed Choline-Deficient High-Fat Diet Reviewed

    Zhao M, Ma L, Honda T, Kato A, Ohshiro T, Yokoyama S, Yamamoto K, Ito T, Imai N, Ishizu Y, Nakamura M, Kawashima H, Tsuji NM, Ishigami M, Fujishiro M.

      Vol. 68 ( 1 ) page: 155 - 163   2023.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s10620-022-07489-6

  32. The presence of high-risk varices after sclerotherapy in biliary atresia Reviewed

    Yokoyama S, Ishizu Y, Honda T, Imai N, Ito T, Yamamoto K, Shirota C, Tainaka T, Sumida W, Makita S, Takimoto A, Nakagawa Y, Takada S, Ishigami M, Uchida H, Kawashima H.

    Pediatr Int   Vol. - ( - ) page: - - -   2022.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/ped.15454

  33. Pipeline Esophagogastric Varices Secondary to Extrahepatic Portal Vein Obstruction Treated Endoscopically with the Assistance of Transileocolic Obliteration Reviewed

    Yokoyama S, Ishizu Y, Honda T, Imai N, Ito T, Yamamoto K, Komada T, Hayashi M, Ishigami M.

      Vol. 61 ( 23 ) page: 3503 - 3511   2022.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.2169/internalmedicine.9404-22

  34. Effect of illness uncertainty on alanine transaminase levels and aspartate aminotransferase levels in patients with nonalcoholic fatty liver disease Reviewed

    Ozawa N, Sato K, Sugimura A, Maki S, Tanaka T, Yamamoto K, Ito T, Ishizu Y, Kuzuya T, Honda T, Ishigami M, Fujishiro M, Ishikawa T, Ando S.

      Vol. 84 ( 4 ) page: 857 - 864   2022.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.18999/nagjms.84.4.857

  35. Decreased appetite is associated with the presence of sarcopenia in patients with cirrhosis Reviewed

    Ishizu Y, Ishigami M, Honda T, Imai N, Ito T, Yamamoto K, Yokoyama S, Ishikawa T, Kawashima H.

    Nutrition   Vol. - ( - ) page: - - -   2022.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.nut.2022.111807

  36. Factors associated with the progression of myosteatosis in patients with cirrhosis Reviewed

    Ishizu Y, Ishigami M, Honda T, Imai N, Ito T, Yamamoto K, Yokoyama S, Ishikawa T, Fujishiro M.

    Nutrition   Vol. - ( - ) page: - - -   2022.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.nut.2022.111777

  37. An improved method to assess skeletal muscle mass in patients with liver cirrhosis based on computed tomography images Reviewed

    Sugiyama Y, Ishizu Y, Ando Y, Yokoyama S, Yamamoto K, Ito T, Imai N, Nakamura M, Honda T, Kawashima H, Ishikawa T, Ishigami M.

      Vol. 52 ( 11 ) page: 937 - 946   2022.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/hepr.13820

  38. Effectiveness of Porous Glass Membrane Pumping Emulsification Device in Transarterial Chemoembolization for Solitary Hepatocellular Carcinoma Reviewed

    Imai N, Ishigami M, Oie Y, Kumagai M, Inukai Y, Yokoyama S, Yamamoto K, Ito T, Ishizu Y, Honda T, Kawashima H.

      Vol. 42 ( 8 ) page: 3947 - 3951   2022.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.21873/anticanres.15889

  39. A case of antiprogrammed death-ligand 1 antibody-induced multisystem immune-related adverse events with pancreatitis and steroid-resistant sclerosing cholangitis Reviewed

    Yamamoto T, Ito T, Mizuno K, Shinya Y, Yamamoto K, Imai N, Ishizu Y, Honda T, Kawashima H, Matsui T, Hase T, Hashimoto N, Ishigami M.

      Vol. 23 ( 7 ) page: 404 - 409   2022.7

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/1751-2980.13122

  40. Changes in Body Composition Predict the Time to Treatment Failure of Lenvatinib in Patients with Advanced Hepatocellular Carcinoma: A Pilot Retrospective Study Reviewed

    Yamamoto T, Imai N, Kuzuya T, Yokoyama S, Yamamoto K, Ito T, Ishizu Y, Honda T, Ishigami M.

    Nutr Cancer   Vol. 74 ( 9 ) page: 3118 - 3127   2022.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1080/01635581.2022.2049322

  41. Immune-related Liver Injury is a Poor Prognostic Factor in Patients with Nonsmall Cell Lung Cancer Treated with Immune Checkpoint Inhibitors Reviewed

    Yamamoto T, Ito T, Hase T, Ishigami M, Mizuno K, Yamamoto K, Imai N, Ishizu Y, Honda T, Shibata H, Hatta T, Yogo N, Yasuda S, Toyoda H, Abe T, Kawashima H, Hashimoto N, Fujishiro M.

      Vol. 40 ( 2 ) page: 189 - 198   2022.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1080/07357907.2021.1994586

  42. Absence of large portal collateral vessels is associated with spontaneous improvement of cirrhotic portal vein thrombosis Reviewed

    Yokoyama S, Ishizu Y, Honda T, Imai N, Ito T, Yamamoto K, Tsuzuki T, Ishigami M.

      Vol. 52 ( 2 ) page: 199 - 209   2022.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/hepr.13725

  43. Obesity and myosteatosis: the two characteristics of dynapenia in patients with cirrhosis Reviewed

    Sugiyama Y, Ishizu Y, Ando Y, Yokoyama S, Yamamoto K, Ito T, Imai N, Nakamura M, Honda T, Kawashima H, Ishikawa T, Ishigami M.

    Eur J Gastroenterol Hepatol   Vol. 33 ( S1 ) page: :e916 - e921   2021.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1097/MEG.0000000000002303

  44. Safety and Efficacy of Glass Membrane Pumping Emulsification Device in Transarterial Chemoembolization for Hepatocellular Carcinoma: First Clinical Outcomes. Reviewed

    Norihiro Imai, Shinya Yokoyama, Kenta Yamamoto, Takanori Ito, Yoji Ishizu, Takashi Honda, Masatoshi Ishigami

    Anticancer research   Vol. 41 ( 11 ) page: 5817 - 5820   2021.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.21873/anticanres.15399.

  45. Absence of large portal collateral vessels is associated with spontaneous improvement of cirrhotic portal vein thrombosis Reviewed

    Shinya Yokoyama, Yoji Ishizu 1, Takashi Honda, Norihiro Imai, Takanori Ito, Kenta Yamamoto, Tomoyuki Tsuzuki, Masatoshi Ishigami

    Hepatology research   Vol. 52 ( 2 ) page: 199 - 209   2021.10

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/hepr.13725.

  46. Immune-related liver injury is a poor prognostic factor in patients with non-small cell lung cancer treated with immune checkpoint inhibitors Reviewed

    Takafumi Yamamoto, Takanori Ito, Tetsunari Hase, Masatoshi Ishigami, Kazuyuki Mizuno, Kenta Yamamoto, Norihiro Imai, Yoji Ishizu, Takashi Honda, Hirofumi Shibata, Takahiro Hatta, Naoyuki Yogo, Satoshi Yasuda, Hidenori Toyoda, Takashi Abe, Hiroki Kawashima, Naozumi Hashimoto, Mitsuhiro Fujishiro

    Cancer investigation     2021.10

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1080/07357907.2021.1994586.

  47. The influence of hepatitis C virus eradication on hepatocarcinogenesis in patients with hemophilia: HCC after HCV eradication in hemophilia. Reviewed

    Inukai Y, Imai N, Yamamoto K, Ito T, Ishizu Y, Honda T, Okamoto S, Kanematsu T, Suzuki N, Matsushita T, Ishigami M, Fujishiro M

    Annals of hepatology     2021.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.aohep.2021.100545

  48. Revisiting Prognosis After Liver Transplant in Patients Positive for Hepatitis C Virus: Focus on Hepatitis C Recurrence-Unrelated Complications. Reviewed

    Ishigami M, Honda T, Ishizu Y, Imai N, Ito T, Yamamoto K, Kamei H, Ogura Y, Fujishiro M

    Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation   Vol. 19 ( 9 ) page: 935 - 942   2021.9

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    Language:English   Publishing type:Research paper (scientific journal)  

  49. Clinical course of liver injury induced by immune checkpoint inhibitors in patients with advanced malignancies Reviewed

    Ito T, Ishigami M, Yamamoto T, Mizuno K, Yamamoto K, Imai N, Ishizu Y, Honda T, Kawashima H, Yasuda S, Toyoda H, Yokota K, Hase T, Nishio N, Maeda O, Kato M, Hashimoto N, Hibi H, Kodera Y, Sone M, Ando Y, Akiyama M, Shimoyama Y, Fujishiro M

    Hepatology international   Vol. 15 ( 5 ) page: 1278 - 1287   2021.8

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    DOI: 10.1007/s12072-021-10238-y

  50. Quality of Life in patients with nonalcoholic fatty liver disease: Structure and related factors focusing on illness uncertainty. Reviewed

    Naoki Ozawa Kazuki Sato Ayumi Sugimura Shigeyoshi Maki Taku Tanaka Kenta Yamamoto Takanori Ito Yoji Ishizu Teiji Kuzuya Takashi Honda Masatoshi Ishigami Mitsuhiro Fujishiro Tetsuya Ishikawa Shoko Ando

    Japan journal of nursing science     2021.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/jjns.12415

  51. Progression After Molecular Targeted Agents: Hepatic Arterial Changes and Transarterial Chemoembolization in Hepatocellular Carcinoma Reviewed

    NORITAKA MATSUDA, NORIHIRO IMAI, TEIJI KUZUYA, KENTA YAMAMOTO, TAKANORI ITO, YOJI ISHIZU, TAKASHI HONDA, MASATOSHI ISHIGAMI and MITSUHIRO FUJISHIRO

    In vivo.   Vol. 35 ( 2 ) page: 1185 - 1189   2021.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.21873/invivo.12367

  52. Impact of visceral fat accumulation on the prognosis of patients with cirrhosis Reviewed

    Yoji Ishizu Masatoshi Ishigami Takashi Honda Norihiro Imai Takanori Ito Kenta Yamamoto Mitsuhiro Fujishiro

    Clinical Nutrition ESPEN     2021.1

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    DOI: https://doi.org/10.1016/j.clnesp.2021.01.008

  53. Safety and efficacy of percutaneous radiofrequency ablation for hepatocellular carcinoma patients with haemophilia Reviewed

    Takafumi Yamamoto Norihiro Imai Kenta Yamamoto Takanori Ito Yoji Ishizu Takashi Honda Shuichi Okamoto Takeshi Kanematsu Nobuaki Suzuki Tadashi Matsushita Masatoshi Ishigami Mitsuhiro Fujishiro

    Haemophilia   Vol. 27 ( 1 ) page: 100 - 107   2021.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/hae.14220

  54. Tolerability of Molecular-targeted Agents for Hepatocellular Carcinoma Treatment in Haemophiliacs Reviewed

    Yamamoto T, Imai N, Yamamoto K, Ito T, Ishizu Y, Honda T, Okamoto S, Kanematsu T, Suzuki N, Matsushita T, Ishigami M, Fujishiro M.

    Anticancer research   Vol. 40 ( 5 ) page: 2569 - 2573   2021

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    DOI: 10.21873/anticanres.15035

  55. The albumin-bilirubin score as a predictor of outcomes in Japanese patients with PBC: an analysis using time-dependent ROC Reviewed

    Ito T, Ishigami M, Morooka H, Yamamoto K, Imai N, Ishizu Y, Honda T,Nishimura D, Tada T, Yasuda S, Toyoda H, Kumada T, Fujishiro

    Scientific reports.   Vol. 10 ( 1 ) page: 17812   2020.10

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    DOI: 10.1038/s41598-020-74732-3

  56. Antifibrotic Effects of 1,25(OH)2D3 on Nonalcoholic Steatohepatitis in Female Mice.

    Ma, Lingyun, Masatoshi Ishigami, Takashi Honda, Shinya Yokoyama, Kenta Yamamoto, Yoji Ishizu, Teiji Kuzuya, Kazuhiko Hayashi, Yoshiki Hirooka, and Hidemi Goto.

    Digestive Diseases and Sciences   Vol. 64 ( 9 ) page: 2581–90   2019

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  57. この症例に学ぶ 体外式腹部超音波検査にて描出しえた早期胃癌の一例 Invited Reviewed

    山本 健太, 熊田 卓, 久永 康宏, 金森 明, 多田 俊史, 北畠 秀介, 曽根 康博

    日本消化器がん検診学会雑誌   Vol. 52 ( 3 ) page: 387-392   2014.5

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  58. 術中色素動注法が切除範囲決定に有用であった小腸angioectasiaの1例(原著論文/症例報告) Reviewed

    山本 健太, 熊田 卓, 桐山 勢生, 谷川 誠, 久永 康宏, 豊田 秀徳, 金森 明, 多田 俊史, 北畠 秀介, 曽根 康博

    日本消化器病学会雑誌   Vol. 111 ( 4 ) page: 773-778   2014.4

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  59. 肝細胞癌と鑑別が困難であったreactive lymphoid hyperplasiaの1例 Reviewed

    山本 健太, 熊田 卓, 桐山 勢生, 谷川 誠, 久永 康宏, 豊田 秀徳, 金森 明, 多田 俊史, 北畠 秀介, 長谷川 綾平, 伊藤 隆徳, 安藤 祐資, 颯田 祐介, 田中 達也, 曽根 康博, 福里 利夫

    肝臓   Vol. 54 ( 11 ) page: 755-764   2013.11

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  60. 腹腔鏡下胆嚢摘出術後13年目に生じた金属クリップを核とした胆管結石の1例 Reviewed

    山本 健太, 金森 明, 桐山 勢生, 谷川 誠, 久永 康宏, 豊田 秀徳, 多田 俊史, 安東 直人, 新家 卓郎, 坂井 圭介, 安田 諭, 安藤 祐資, 木村 純, 曽根 康博, 熊田 卓

    日本消化器内視鏡学会雑誌   Vol. 55 ( 5 ) page: 1667-1672   2013.5

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  61. Oral supplementation with branched-chain amino acid granules prevents hepatocarcinogenesis in patients with hepatitis C-related cirrhosis: A propensity score analysis Reviewed

    Toshifumi Tada Takashi Kumada Hidenori Toyoda Seiki Kiriyama Makoto Tanikawa Yasuhiro Hisanaga Akira Kanamori Shusuke Kitabatake Takuro Niinomi Takanori Ito Ryohei Hasegawa Yusuke Ando Kenta Yamamoto Tatsuya Tanaka

    Hepatology research   Vol. 44 ( 3 ) page: 288 - 295   2013.4

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  62. Effect of nucleos(t)ide analogue therapy on hepatocarcinogenesis in chronic hepatitis B patients Reviewed

    Kumada T, Toyoda H, Tada T, Kiriyama S, Tanikawa M, Hisanaga Y, Kanamori A, Niinomi T, Yasuda S, Andou Y, Yamamoto K, Tanaka J

    Journal of Hepatology   Vol. 58 ( 3 ) page: 427-33   2013

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  63. 肝切除を基本とした肝細胞癌の治療戦略 Invited Reviewed

    多田 俊史, 熊田 卓, 桐山 勢生, 谷川 誠, 久永 康宏, 豊田 秀徳, 金森 明, 新家 卓郎, 長谷川 綾平, 伊藤 隆徳, 安田 諭, 安藤 祐資, 山本 健太, 田中 達也

    消化器内科   Vol. 55 ( 5 ) page: 612-616   2012.11

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  64. この画像から何が読めるか? 肝腫瘤(図説) Invited Reviewed

    山本 健太, 熊田 卓, 豊田 秀徳, 多田 俊史

    肝胆膵画像   Vol. 14 ( 6 ) page: 542-545   2012.9

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  65. B型肝炎に対する核酸アナログ投与例の長期予後 Invited Reviewed

    多田 俊史, 熊田 卓, 桐山 勢生, 谷川 誠, 豊田 秀徳, 久永 康宏, 金森 明, 新家 卓郎, 安東 直人, 坂井 圭介, 安田 諭, 木村 純, 安藤 祐資, 山本 健太

    消化器内科   Vol. 54 ( 5 ) page: 608-613   2012.5

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  66. FOLFIRI+Panitumumab療法中に発症した薬剤性肺障害に対してステロイド・パルス療法が奏効したS状結腸癌の1例 Reviewed

    山本 健太, 加藤 俊夫, 進藤 丈, 安藤 守秀, 安部 崇, 白木 晶, 中島 治典, 雪田 洋介

    癌と化学療法   Vol. 53 ( 3 ) page: 326-330   2011.9

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  67. 肝発癌を視野に入れたB型肝炎の治療戦略 Invited Reviewed

    坂井 圭介, 熊田 卓, 豊田 秀徳, 桐山 勢生, 谷川 誠, 久永 康宏, 金森 明, 多田 俊史, 新家 卓郎, 安東 直人, 安田 諭, 安藤 祐資, 山本 健太, 木村 純

    消化器内科   Vol. 53 ( 3 ) page: 326-330   2011.9

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  68. 特異な形態を示し経カテーテル的動脈塞栓術を施行した膵十二指腸動脈瘤破裂の1例 Reviewed

    山本 健太, 熊田 卓, 桐山 勢生, 谷川 誠, 久永 康宏, 豊田 秀徳, 金森 明, 多田 俊史, 荒川 恭宏, 藤森 将志, 新家 卓郎, 安東 直人

    胆道   Vol. 24 ( 4 ) page: 603-610   2010.10

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  69. コイン型リチウム電池誤飲により食道潰瘍を来した2例 後遺症を残さなかった1例と後遺症を残した1例 Reviewed

    山本 健太, 岩田 晶子, 都間 佑介, 田中 龍一, 山本 崇裕, 永田 智子, 伊藤 貴美子, 鹿野 博明, 中嶋 義記, 近藤 富雄

    小児科臨床   Vol. 63 ( 7 ) page: 1667-1673   2010.7

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  70. 造影超音波検査で特徴的な所見が得られた肝細胞腺腫の1例 Reviewed

    山本 健太, 熊田 卓, 桐山 勢生, 曽根 康博, 谷川 誠, 久永 康宏, 豊田 秀徳, 金森 明, 渥美 裕之, 高木 万起子, 中野 聡, 荒川 恭宏, 藤森 将志, 高橋 健一, 竹島 賢治, 乙部 克彦

    肝胆膵画像   Vol. 11 ( 5 ) page: 564-570   2009.9

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Books 1

  1. 消化器内科専攻医マニュアル

    名古屋大学消化器内科( Role: Joint author)

    ㈱シービーアール  2022.2  ( ISBN:4908083738

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    Total pages:636   Responsible for pages:9   Language:Japanese Book type:Textbook, survey, introduction

Presentations 22

  1. 生活習慣病・メタボリックシンドロームからの消化器疾患 次世代シーケンサーを用いた慢性肝疾患患者の腸内細菌叢と肥満・栄養に関する検討

    山本 健太, 廣岡 芳樹, 後藤 秀実

    日本消化器病学会  2017.3 

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  2. 慢性肝疾患患者における生活習慣による腸内細菌への影響

    山本 健太, 石上 雅敏, 田中 卓, 安藤 祐資, 伊藤 隆徳, 安田 諭, 野村 彩, 加藤 幸一郎, 石津 洋二, 葛谷 貞二, 本多 隆, 林 和彦, 廣岡 芳樹, 石川 哲也, 後藤 秀実

    肝臓学会  2017.4 

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  3. 初回治療TACEを施行した高齢患者における予後の検討

    山本 健太, 石上 雅敏, 武藤 久哲, 横山 晋也, 田中 卓, 安藤 祐資, 伊藤 隆徳, 安田 諭, 石津 洋二, 葛谷 貞二, 本多 隆, 林 和彦, 廣岡 芳樹, 後藤 秀実

    肝臓学会  2018.4 

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  4. Attenuation Imagingに対する級内相関係数を用いた検者内信頼性の検討

    山本 健太, 石上 雅敏, 本多 隆, 葛谷 貞二, 石津 洋二, 廣岡 芳樹, 川嶋 啓揮, 中村 正直, 大野 栄三郎, 後藤 秀実

    日本超音波医学会  2018.4 

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  5. 次世代シーケンサーを用いた慢性肝疾患患者における腸内細菌の多様性を変化させる因子の検討

    山本 健太, 本多 隆, 安藤 祐資, 田中 卓, 横山 晋也, 石津 洋二, 葛谷 貞二, 林 和彦, 石上 雅敏, 後藤 秀実

    JDDW  2017.9 

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  6. 肝線維化:診断・治療の基礎と臨床 C型肝炎患者におけるFib4 indexを用いた線維化度と腸内細菌叢に関する検討

    山本 健太, 廣岡 芳樹, 後藤 秀実

    日本消化器病学会  2018.3 

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  7. 消化管疾患と肝疾患の関連-消化管・肝臓間の相互の影響- Child-Pugh分類AもしくはBの慢性肝疾患患者におけるProton pump inhibitor使用による腸内細菌叢の比較

    山本 健太, 石上 雅敏, 廣岡 芳樹

    JDDW  2018.9 

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  8. 肝疾患における臓器連関の役割 ランダムフォレストを用いた慢性肝疾患患者における筋肉量減少と関連ある腸内細菌叢の同定への試み

    山本 健太, 本多 隆, 石上 雅敏

    肝臓学会西部会  2021.11 

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  9. 腸内細菌と肝疾患 慢性肝疾患患者における筋肉量、血清分岐鎖アミノ酸濃度、細菌叢の相関に関する検討

    山本 健太, 本多 隆, 藤城 光弘

    JDDW  2021.9 

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  10. 消化吸収と臓器相関 慢性肝疾患患者における生活習慣・排便状況調査と腸内細菌叢に与える影響

    山本 健太, 本多 隆, 藤城 光弘

    日本消化器病学会  2021.3 

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  11. 肝硬変による入院イベントと腸内細菌叢の関連性

    山本 健太, 本多 隆, 山本 崇文, 犬飼 庸介, 杉山 由晃, 吉岡 直輝, 水野 和幸, 武藤 久哲, 横山 晋也, 伊藤 隆徳, 今井 則博, 石津 洋二, 石上 雅敏, 藤城 光弘

    肝臓学会  2021.4 

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  12. 慢性肝疾患患者における筋肉量減少と腸内細菌叢及び細菌叢が行うアミノ酸代謝に関する検討

    山本 健太, 本多 隆, 山本 崇文, 犬飼 庸介, 杉山 由晃, 吉岡 直輝, 水野 和幸, 武藤 久哲, 横山 晋也, 田中 卓, 伊藤 隆徳, 石津 洋二, 葛谷 貞二, 石上 雅敏, 藤城 光弘

    JDDW  2020.9 

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  13. 肝疾患におけるバイオマーカー研究 慢性肝疾患患者における腸内細菌のPredicted Functional Dysbiosisに影響を与える因子についての検討

    山本 健太, 本多 隆, 石上 雅敏

    肝臓学会  2020.4 

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  14. 進行肝細胞癌に対するソラフェニブ治療における有害事象及び治療効果と腸内細菌叢の検討

    山本 健太, 葛谷 貞二, 本多 隆, 杉山 由晃, 吉岡 直輝, 水野 和幸, 武藤 久哲, 横山 晋也, 田中 卓, 伊藤 隆徳, 石津 洋二, 石上 雅敏, 藤城 光弘

    肝臓学会西部会  2019.11 

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  15. ジエチルニトロサミンを用いたコリン欠乏高脂肪食によるNASHマウスモデルにおける発癌の検討

    山本 健太, 本多 隆, 水野 和幸, 武藤 久哲, 横山 晋也, 田中 卓, 安藤 祐資, 伊藤 隆徳, 石津 洋二, 葛谷 貞二, 石井 雅敏, 廣岡 芳樹

    日本消化器病学会  2019.3 

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  16. 門脈圧亢進症診療の新しい潮流 門脈圧亢進症における腸内細菌叢の検討

    山本 健太, 石上 雅敏, 廣岡 芳樹

    日本消化器病学会  2019.3 

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  17. 次世代シークエンサを用いたウイルスゲノム・マイクロバイオーム・エクソゾーム解析による肝疾患研究 血小板数とC型肝炎患者における腸内細菌叢及び予測機能遺伝子に関する検討

    山本 健太, 本多 隆, 石上 雅敏

    肝臓学会西部会  2018.11 

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  18. Focusing on the oral origin bacteria in the gut Invited International coauthorship International conference

    Kenta Yamamoto

    United European Gastroenterology Week 2021  2021.10.4 

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  19. INVESTIGATING THE RELATIONSHIP BETWEEN GUT MICROBIOME AND FIBROSIS MARKERS IN PATIENTS WITH VIRAL HEPATITIS International conference

    K. Yamamoto, T. Honda, Y. Inukai, S. Yokoyama, T. Ito, N. Imai, Y. Ishizu, H. Kawashima, M. Ishigami

    United European Gastroenterology Week 2023  2023.10.14 

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  20. Correlation Between Gut Microbiota and Clinical Parameters in Patients with Alcoholic Liver Disease International conference

    Kenta Yamamoto, Takashi Honda, Shinya Yokoyama, Takanori Ito, Norihiro Imai, Yoji Ishizu, Masatoshi Ishigami, Tetsuya Ishikawa, Hiroki Kawashima

    The 3rd JSH International Liver Conference  2023.9.7 

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  21. The Effect of Elobixibat on Tumorigenesis in the NASH Mice Model International conference

    Kenta Yamamoto, Yoshiaki Sugiyama, Takashi Honda, Asuka Kato, Hisanori Muto, Shinya Yokoyama, Takanori Ito, Norihiro Imai, Yoji Ishizu, Masatoshi Ishigami, Hiroki Kawashima.

    The Asian Pacific Association for the Study of the Liver single topic conference  2022.9.1 

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  22. Understanding the role of the microbiome in inflammatory diseases Invited International conference

    Kenta Yamamoto, Anne-​Kathrin Classen

    The Friburg univercity Rising Stars Conference  2022.3.23 

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KAKENHI (Grants-in-Aid for Scientific Research) 2

  1. ネットワーク解析を用いた腸内細菌が合成するアミノ酸と肝硬変・筋肉量の関連性の解明

    Grant number:21K15970  2021.4 - 2024.3

    日本学術振興会  科学研究費  若手研究

    山本 健太

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\4550000 ( Direct Cost: \3500000 、 Indirect Cost:\1050000 )

    肝硬変患者における腸内細菌叢が作るアミノ酸と筋肉量の関連性を明確にし、有用もしくは有害な細菌を同定することでサルコペニアや肝性脳症のリスク評価を可能とするバイオマーカーの発見と治療・予防薬の開発を目指す。肝硬変患者ではアンモニア産生菌や分岐鎖アミノ酸以外のアミノ酸合成菌が多く、アミノ酸を生成する際に窒素をとりあう「細菌による競合」が生じている可能性がある。この解明には単一の細菌を検出する目的ではなく肝硬変による腸内細菌叢の乱れ、競合する細菌など複数の有用な細菌や競合する細菌のネットワークを明らかにすることで新たな視点により人体に与える影響を解明する。

  2. サルコペニア患者に対する腸内細菌叢への介入による効果的な運動療法の開発

    Grant number:21K11261  2021.4 - 2024.3

    日本学術振興会  科学研究費  基盤研究(C)

    石津 洋二,本多 隆 ,梅垣 宏行

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    Authorship:Coinvestigator(s)  Grant type:Competitive

    Grant amount:\4160000 ( Direct Cost: \3200000 、 Indirect Cost:\960000 )