Organization
Nagoya University Hospital Cardiology Assistant Professor of Hospital
Title
Assistant Professor of Hospital
YAMAGUCHI Shukuro
Degree 1
-
博士（医学） （ 2020.11 名古屋大学 ）
Research Areas 1
-
Life Science / Cardiology
Current Research Project and SDGs 2
-
重症虚血肢に対する脂肪組織由来再生（幹）細胞を用いた血管新生療法
-
心血管疾患における核酸医薬の開発
Research History 4
-
Nagoya University Nagoya University Hospital Cardiology Assistant Professor of Hospital
2025.1
-
Nagoya University Designated Assistant Professor
2024.9 - 2024.12
-
Cedars-Sinai Medical Center Smidt Heart Institute 研究員
2021.4 - 2024.8
-
Nagoya University Assistant Professor of Hospital
2020.4 - 2021.3
Professional Memberships 2
-
日本循環器学会
2013.4
-
日本内科学会
2013.4
Papers 17
-
Therapeutic Lymphangiogenesis Using Induced Cardiac Fibroblasts Protects the Heart From Heart Failure With Preserved Ejection Fraction Progression by Exerting Anti-Inflammatory and Antifibrotic Effects.
Luo H, Shimizu Y, Iwamiya T, Matsuoka Y, Chen X, Liu T, Che Y, Hayashi T, Pu Z, Yamaguchi S, Sakamoto K, Murohara T
Circulation journal : official journal of the Japanese Circulation Society 2026.1
-
Augmentation of DNA exonuclease TREX1 in macrophages as a therapy for cardiac ischemic injury.
Ibrahim AG, Ciullo A, Komuro H, Miyamoto K, Jones XM, Yamaguchi S, Tsi K, Anderson J, Godoy Coto J, Kitka D, Liao K, Li C, Rannou A, Nawaz A, Morris A, Marbán CH, Lee J, Manriquez N, Hong Y, Naveen Kumar A, Dawkins JF, Rogers RG, Marbán E
Science translational medicine Vol. 17 ( 827 ) page： eadp1338 2025.12
-
Oral Bioavailability of a Noncoding RNA Drug, TY1, That Acts on Macrophages. Open Access
Yamaguchi S, Miyamoto K, Jones XM, Ciullo A, Tsi K, Anderson J, Komuro H, Soussi S, Morris A, Kitka D, Liu DZ, Nguyen A, Marbán E, Ibrahim AGE
Journal of extracellular biology Vol. 4 ( 8 ) page： e70081 2025.8
-
Myonectin stimulates endothelial angiogenic activity in vitro and in vivo.
Masutomi T, Ouchi N, Yamaguchi S, Ohashi K, Otaka N, Pu Z, Shimizu Y, Murohara T, Shibata R
Nagoya journal of medical science Vol. 87 ( 2 ) page： 285 - 294 2025.5
-
Intravenous and oral administration of the synthetic RNA drug, TY1, reverses heart failure with preserved ejection fraction in mice.
Miyamoto K, Jones XM, Yamaguchi S, Ciullo A, Li C, Coto JG, Tsi K, Anderson J, Morris A, Marbán E, Ibrahim AG
Basic research in cardiology Vol. 120 ( 2 ) page： 363 - 371 2025.4
-
A novel micropeptide, Slitharin, exerts cardioprotective effects in myocardial infarction.
Ibrahim AGE, Ciullo A, Yamaguchi S, Li C, Antes T, Jones X, Li L, Murali R, Maslennikov I, Sundararaman N, Soetkamp D, Cingolani E, Van Eyk J, Marbán E
Proteomics. Clinical applications Vol. 18 ( 5 ) page： e2300128 2024.9
-
Omentin Modulates Chronic Cardiac Remodeling After Myocardial Infarction. Open Access
Ito M, Shibata R, Ohashi K, Otaka N, Yamaguchi S, Ogawa H, Enomoto T, Masutomi T, Murohara T, Ouchi N
Circulation reports Vol. 5 ( 2 ) page： 46 - 54 2023.2
-
TDO2-augmented fibroblasts secrete EVs enriched in immunomodulatory Y-derived small RNA. Open Access
Ciullo A, Peck K, Jones X, Yamaguchi S, Morris AA, Kumar AN, Li L, Lee J, Dos Santos RM, Cingolani E, Ibrahim AG
Journal of extracellular biology Vol. 2 ( 2 ) page： e73 2023.2
-
Adipose-derived regenerative cells as a promising therapy for cardiovascular diseases: an overview. Open Access
Yamaguchi S, Shimizu Y, Murohara T, Shibata R
Nagoya journal of medical science Vol. 84 ( 2 ) page： 208 - 215 2022.5
-
Zinc deficiency impairs ischemia-induced angiogenesis. Open Access
Tsuruoka T, Kodama A, Yamaguchi S, Masutomi T, Koyama A, Murohara T, Komori K, Shibata R
JVS-vascular science Vol. 3 page： 30 - 40 2022
-
Adverse Effect of Circadian Rhythm Disorder on Reparative Angiogenesis in Hind Limb Ischemia. Open Access
Tsuzuki K, Shimizu Y, Suzuki J, Pu Z, Yamaguchi S, Fujikawa Y, Kato K, Ohashi K, Takefuji M, Bando YK, Ouchi N, Calvert JW, Shibata R, Murohara T
Journal of the American Heart Association Vol. 10 ( 16 ) page： e020896 2021.8
-
Suzuki J, Shimizu Y, Tsuzuki K, Pu Z, Narita S, Yamaguchi S, Katagiri T, Iwata E, Masutomi T, Fujikawa Y, Shibata R, Murohara T
American journal of physiology. Heart and circulatory physiology Vol. 320 ( 1 ) page： H447 - H457 2021.1
-
Katagiri T, Kondo K, Shibata R, Hayashida R, Shintani S, Yamaguchi S, Shimizu Y, Unno K, Kikuchi R, Kodama A, Takanari K, Kamei Y, Komori K, Murohara T
Scientific reports Vol. 10 ( 1 ) page： 16045 2020.9
-
Shibata R, Yamaguchi S, Murohara T
Circulation journal : official journal of the Japanese Circulation Society Vol. 84 ( 4 ) page： 549 - 550 2020.3
-
Ogawa H, Ohashi K, Ito M, Shibata R, Kanemura N, Yuasa D, Kambara T, Matsuo K, Hayakawa S, Hiramatsu-Ito M, Otaka N, Kawanishi H, Yamaguchi S, Enomoto T, Abe T, Kaneko M, Takefuji M, Murohara T, Ouchi N
Cardiovascular research Vol. 116 ( 1 ) page： 237 - 249 2020.1
-
C1q/TNF-Related Protein 9 Promotes Revascularization in Response to Ischemia via an eNOS-Dependent Manner. Open Access
Yamaguchi S, Shibata R, Ohashi K, Enomoto T, Ogawa H, Otaka N, Hiramatsu-Ito M, Masutomi T, Kawanishi H, Murohara T, Ouchi N
Frontiers in pharmacology Vol. 11 page： 1313 2020
-
Eed/Sox2 regulatory loop controls ES cell self-renewal through histone methylation and acetylation. Open Access
Ura H, Murakami K, Akagi T, Kinoshita K, Yamaguchi S, Masui S, Niwa H, Koide H, Yokota T
The EMBO journal Vol. 30 ( 11 ) page： 2190 - 204 2011.6