Updated on 2023/04/05


MATSUYAMA, Hironori J.
Graduate School of Science Neuroscience Institute Designated assistant professor
Designated assistant professor
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Degree 1

  1. 博士(理学) ( 2015.3   名古屋大学 ) 

Research Interests 7

  1. Nonlinear physics

  2. 非平衡物理学

  3. Neurobiology

  4. Dynamical system

  5. Chaos

  6. 動物行動学

  7. C. elegans

Research Areas 2

  1. Natural Science / Mathematical physics and fundamental theory of condensed matter physics

  2. Life Science / Neuroscience-general


Papers 5

  1. AWC thermosensory neuron interferes with information processing in a compact circuit regulating temperature-evoked posture dynamics in the nematode Caenorhabditis elegans

    Amane Kano, Hironori J. Matsuyama, Shunji Nakano, Ikue Mori

    Neuroscience Research     2022.11

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Elsevier BV  

    DOI: 10.1016/j.neures.2022.11.001


  2. OLA-1, an Obg-like ATPase, integrates hunger with temperature information in sensory neurons in C. elegans. Reviewed International journal

    Ichiro Aoki, Paola Jurado, Kanji Nawa, Rumi Kondo, Riku Yamashiro, Hironori J Matsuyama, Isidre Ferrer, Shunji Nakano, Ikue Mori

    PLoS Genetics   Vol. 18 ( 6 ) page: e1010219   2022.6

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    Language:English   Publishing type:Research paper (scientific journal)  

    Animals detect changes in both their environment and their internal state and modify their behavior accordingly. Yet, it remains largely to be clarified how information of environment and internal state is integrated and how such integrated information modifies behavior. Well-fed C. elegans migrates to past cultivation temperature on a thermal gradient, which is disrupted when animals are starved. We recently reported that the neuronal activities synchronize between a thermosensory neuron AFD and an interneuron AIY, which is directly downstream of AFD, in well-fed animals, while this synchrony is disrupted in starved animals. However, it remained to be determined whether the disruption of the synchrony is derived from modulation of the transmitter release from AFD or from the modification of reception or signal transduction in AIY. By performing forward genetics on a transition of thermotaxis behavior along starvation, we revealed that OLA-1, an Obg-like ATPase, functions in AFD to promote disruption of AFD-AIY synchrony and behavioral transition. Our results suggest that the information of hunger is delivered to the AFD thermosensory neuron and gates transmitter release from AFD to disrupt thermotaxis, thereby shedding light onto a mechanism for the integration of environmental and internal state to modulate behavior.

    DOI: 10.1371/journal.pgen.1010219



  3. Age‐dependent changes in response property and morphology of a thermosensory neuron and thermotaxis behavior in Caenorhabditis elegans Reviewed International coauthorship

    Tzu‐Ting Huang, Hironori J. Matsuyama, Yuki Tsukada, Aakanksha Singhvi, Ru‐Ting Syu, Yun Lu, Shai Shaham, Ikue Mori, Chun‐Liang Pan

    Aging Cell   Vol. 19 ( 5 ) page: e13146   2020.5

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    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:Wiley  

    DOI: 10.1111/acel.13146

    Web of Science



    Other Link: https://onlinelibrary.wiley.com/doi/full-xml/10.1111/acel.13146

  4. Neural Coding of Thermal Preferences in the Nematode Caenorhabditis elegans Reviewed

    Hironori J. Matsuyama, Ikue Mori

    eneuro   Vol. 7 ( 3 ) page: ENEURO.0414 - 19.2020   2020.5

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:Society for Neuroscience  

    DOI: 10.1523/ENEURO.0414-19.2020



  5. Multistage slow relaxation in a Hamiltonian system: The Fermi-Pasta-Ulam model Reviewed

    Hironori J. Matsuyama, Tetsuro Konishi

    Physical Review E   Vol. 92   page: 022917   2015.8

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: https://doi.org/10.1103/PhysRevE.92.022917


  1. 線虫における温度嗜好性の神経メカニズム

    松山 裕典, 森 郁恵

    月刊細胞 THE CELL   Vol. 52 ( 14 ) page: 46(832) - 51(837)   2020.12

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    Authorship:Lead author   Language:Japanese