Updated on 2023/03/27

写真a

 
MATSUI Toshinori
 
Organization
Nagoya University Hospital Assistant professor of hospital
Title
Assistant professor of hospital

Degree 1

  1. 医学博士 ( 2015.2   名古屋大学 ) 

 

Papers 5

  1. The Application of Mixed Reality in Bronchoscopy Simulation Training: A Feasibility Study

    Okachi Shotaro, Sakurai Manami, Matsui Toshinori, Ito Takayasu, Matsuzawa Reiko, Morise Masahiro, Wakahara Keiko, Ishii Makoto, Fujiwara Michitaka

    SURGICAL INNOVATION     2023.3

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    Publisher:Surgical Innovation  

    DOI: 10.1177/15533506231160201

    Web of Science

    Scopus

  2. Mixed Realityを活用した気管支鏡トレーニング支援

    岡地 祥太郎, 桜井 麻奈美, 松井 利憲, 森瀬 昌宏, 伊藤 貴康, 長瀬 文太, 福田 夏帆, 若原 恵子, 石井 誠, 藤原 道隆

    日本VR医学会学術大会プログラム・抄録集   Vol. 2022 ( 0 ) page: 27 - 27   2022.8

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    Language:Japanese   Publisher:日本VR医学会  

    DOI: 10.24764/jsmvr.2022.0_27

    CiNii Research

  3. A case of antiprogrammed death-ligand 1 antibody-induced multisystem immune-related adverse events with pancreatitis and steroid-resistant sclerosing cholangitis

    Yamamoto Takafumi, Ito Takanori, Mizuno Kazuyuki, Shinya Yokoyama, Yamamoto Kenta, Imai Norihiro, Ishizu Yoji, Honda Takashi, Kawashima Hiroki, Matsui Toshinori, Hase Tetsunari, Hashimoto Naozumi, Ishigami Masatoshi

    JOURNAL OF DIGESTIVE DISEASES   Vol. 23 ( 7 ) page: 404 - 409   2022.7

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    Language:English   Publisher:Journal of Digestive Diseases  

    DOI: 10.1111/1751-2980.13122

    Web of Science

    Scopus

    PubMed

  4. HER2 targeting near-infrared photoimmunotherapy for a CDDP-resistant small-cell lung cancer Reviewed

    Takahashi Kazuomi, Taki Shunichi, Yasui Hirotoshi, Nishinaga Yuko, Isobe Yoshitaka, Matsui Toshinori, Shimizu Misae, Koike Chiaki, Sato Kazuhide

    CANCER MEDICINE   Vol. 10 ( 24 ) page: 8808 - 8819   2021.12

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Cancer Medicine  

    Background: Human epidermal growth factor receptor 2 (HER2) is tyrosine kinase receptor that belongs to the ErbB family and is overexpressed on the membrane surface of various cancer cells, including small cell lung cancer (SCLC); however, no HER2 targeted therapy for SCLC have yet been established. Near-infrared photoimmunotherapy (NIR-PIT) is a novel cancer therapy based on photo-absorber, IRDye-700DX (IR700), -antibody conjugates, and near-infrared (NIR) light. Methods: We used HER2-positive SCLC parental cell lines (SBC-3) and its chemoresistant cell lines, and examined therapeutic efficacy of HER2 targeting NIR-PIT using anti HER2 antibody trastuzumab. Results: We found that HER2 expression was upregulated on chemoresistant cell lines, especially cisplatin-resistance (SBC-3/CDDP). In vitro, the rate of cell death increased with the amount of NIR-light irradiation, and it was significantly higher in SBC-3/CDDP than in SBC-3. In vivo, tumor growth was more suppressed in SBC-3/CDDP group than in SBC-3 group, and survival period tended to be prolonged. Conclusion: In this study, we demonstrated that HER2 targeting NIR-PIT using trastuzumab is promising therapy for HER2-positive SCLC, and is more effective when HER2 expression is upregulated due to CDDP resistance, suggesting that the HER2 expression level positively corelated with the efficacy of NIR-PIT.

    DOI: 10.1002/cam4.4381

    Web of Science

    Scopus

    PubMed

  5. Near Infrared Photoimmunotherapy Targeting DLL3 Against Small Cell Lung Cancer

    Isobe Y., Sato K., Takahashi K., Taki S., Yasui H., Nishinaga Y., Matsui T., Hasegawa Y.

    JOURNAL OF THORACIC ONCOLOGY   Vol. 14 ( 10 ) page: S536 - S537   2019.10

MISC 1

  1. Bedside cannulation for veno-venous extracorporeal membrane oxygenation using portable X-ray system in a coronavirus disease patient. Reviewed

    Kondo T, Kuwayama T, Hiraiwa H, Kasugai D, Goto Y, Numaguchi A, Katsu T, Matsui T, Hashimoto N, Tanaka A, Morimoto R, Okumura T, Murohara T

    Journal of cardiology cases   Vol. 25 ( 3 ) page: 185 - 187   2022.3

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    Language:English   Publishing type:Rapid communication, short report, research note, etc. (scientific journal)   Publisher:Journal of Cardiology Cases  

    Transportation of patients with coronavirus disease (COVID)-19 outside isolation rooms should be avoided to prevent further spread of the disease. Here, we report a safe and accurate bedside cannulation method for veno-venous extracorporeal membrane oxygenation (VV-ECMO) in a COVID-19 patient in the intensive care unit. A 71-year-old man was admitted to our hospital and diagnosed as having COVID-19 pneumonia. We decided to initiate VV-ECMO therapy because maintaining blood oxygen saturation was difficult despite the mechanical ventilation. We placed two flat-panel detectors behind the patient's chest and the right inguinal area. We repeatedly imaged and monitored insertion of wires and cannulas using a portable X-ray system. Cannulas were successfully inserted in the appropriate position, and VV-ECMO was initiated without any complications. <Learning objective: Transportation of patients with coronavirus disease outside isolation rooms carries the risk of further spread of the disease. By repeatedly acquiring images using a portable X-ray system, safe and accurate cannulation for veno-venous extracorporeal membrane oxygenation cannulation can be performed at the bedside in the intensive care unit.>

    DOI: 10.1016/j.jccase.2021.09.008

    Scopus

    PubMed

KAKENHI (Grants-in-Aid for Scientific Research) 1

  1. Targeting of Numb-EphB3/4 molecular interaction and elucidation of signaling mechanism in pulmonary fibrosis

    Grant number:20K17179  2020.4 - 2023.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Early-Career Scientists

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    Authorship:Principal investigator 

    Grant amount:\4290000 ( Direct Cost: \3300000 、 Indirect Cost:\990000 )

 

Teaching Experience (On-campus) 3

  1. 基本的臨床技能実習【胸部X-P読影】

    2022

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    胸部X-P読影の講義後、実際のレントゲンを使用しての読影実習

  2. 臨床実習II 第I, II期

    2022

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    臨床実習II 第I, II期 学生一名を実習期間を通じて指導 平均4コマ/週程度で担当患者や関連する医学についてDiscussion

  3. 臨床実習I 呼吸器内科

    2022

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    臨床実習I 呼吸器内科 木曜午前にMxRセンターにて胸腔穿刺についての講義ならびにシミュレータを使用しての実習