研究者詳細 - 森岡　悠

Laryngeal Kaposi's Sarcoma Complicated by the Immune Reconstitution Inflammatory Syndrome in an HIV-infected Patient

Kato Hirofumi, Yanagisawa Naoki, Morioka Hiroshi, Sasaki Shugo, Sekiya Noritaka, Suganuma Akihiko, Imamura Akifumi, Ajisawa Atsushi

INTERNAL MEDICINE 55 巻 ( 8 ) 頁： 1001 - 1005 2016年

掲載種別：研究論文（学術雑誌）出版者・発行元：Internal Medicine

We herein report a case of laryngeal Kaposi's sarcoma (KS) complicated by immune reconstitution inflammatory syndrome in a human immunodeficiency virus (HIV)-infected patient. The patient initially presented with KS involving the larynx, which was successfully treated with pegylated liposomal doxorubicin (PLD) and antiretroviral therapy (ART). PLD was discontinued after 2 courses because of a marked clinical improvement; however, the patient experienced progressive odynophagia and dyspnea 2 months after the initiation of ART. Laryngoscopy revealed a severely swollen, inflamed epiglottis. The readministration of PLD was successful, and the patient was thereafter discharged without any subsequent complications.

DOI： 10.2169/internalmedicine.55.5813

Disseminated Mycobacterium abscessus Infection Following Septic Arthritis A Case Report and Review of the Literature 国際誌

Fukui Shoichi, Sekiya Noritaka, Takizawa Yasunobu, Morioka Hiroshi, Kato Hirofumi, Aono Akio, Chikamatsu Kinuyo, Mitarai Satoshi, Kobayashi Satomi, Kamei Satoshi, Setoguchi Keigo

MEDICINE 94 巻 ( 21 ) 頁： e861 2015年5月

A型肝炎ワクチン(エイムゲンとHavrix)接種後の抗体価と互換性に関する検討

菊池均, 宮津光伸, 永田俊人, 後藤泰浩, 山本悦子, 森岡悠, 佐藤好隆

日本渡航医学会誌 = Journal of the Japanese Society of Travel and Health 9 巻 ( 1 ) 頁： 48 - 50 2015年

P0578-22-AM 注射用抗菌薬届出システムの構築と適正使用に向けた介入方法の検討(感染制御(その他)1,ポスター発表,一般演題,医療薬学の進歩と未来-次の四半世紀に向けて-)

加藤善章, 八木哲也, 山田清文, 山本雅人, 稲垣孝行, 手塚宜行, 森岡悠, 平林亜希, 井口光孝, 加藤大三, 冨田ゆうか

日本医療薬学会年会講演要旨集 25 巻 ( 0 ) 2015年

[Evaluation of HIV-infected patients suspected as having HIV-associated neurocognitive disorders].

Morioka H, Kishida S, Imamura A, Sekiya N, Yanagisawa N, Suganuma A, Ajisawa A

Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases 88 巻 ( 2 ) 頁： 141 - 8 2014年3月

掲載種別：研究論文（学術雑誌）出版者・発行元：Kansenshōgaku zasshi. The Journal of the Japanese Association for Infectious Diseases

背景：抗HIV 療法の進歩によってHIV 感染者の長期生存が可能になってきた現在，HIV 関連神経認知障害（HAND）が問題となりつつある．本邦においてHAND の報告は少なく，臨床像や有病率は明らかではない．対象・方法：都立駒込病院において，平成18 年度のエイズ研究事業で作成された8 つの神経心理検査からなるHIV 感染者高次機能評価バッテリーが30 人のHIV 感染者に施行された．中枢神経合併症のため5 人が除外され，HAND の合併が疑われた25 人の患者背景，頭部MRI 所見，髄液所見，神経心理検査結果を重症度別に比較した．また，バッテリー内の一部の検査を組み合わせて，簡易バッテリーとして用いた場合の検討を行った．結果：25 人中19 人（76％）がHAND と診断され，その内訳は7 人がHIV 認知症，8 人が軽度神経認知障害，4 人が無症候性神経認知障害であった．重症度別では，患者背景，頭部MRI 所見，髄液所見はいずれも一定の傾向が見られなかった．簡易バッテリーの検討では，International HIV Dementia Scale もしくは符号の検査のいずれかがカットオフ値以下であった場合，94.7％のHAND 症例は検出可能であった．結論：臨床的にHAND の合併が疑われた大部分のHIV 感染者に対してHAND の診断がなされた．HIV 感染者高次機能評価バッテリー内の一部の神経心理検査は有用であったが，現行のHAND の診断基準に合致したものに改訂する必要がある．

DOI： 10.11150/kansenshogakuzasshi.88.141

Bilateral Facial Nerve Palsy and Appendicitis Occurring during Acute Retroviral Syndrome

Morioka Hiroshi, Sakamoto Naoya, Iwabuchi Sentaro, Ohnishi Kenji

INTERNAL MEDICINE 53 巻 ( 2 ) 頁： 155 - 158 2014年

掲載種別：研究論文（学術雑誌）出版者・発行元：Internal Medicine

We herein report the case of 41-year-old homosexual man who presented to our hospital with typical acute retroviral syndrome. Complications of bilateral facial nerve palsy and appendicitis appeared eight days after admission. The bilateral facial nerve palsy spontaneously recovered one month later; however, the appendicitis required surgical intervention. To our knowledge, this is the first reported case of appendicitis related to acute retroviral syndrome.

DOI： 10.2169/internalmedicine.53.0636

神経心理検査で改善が示唆されたHIV-associated dementiaの1例

森岡悠, 今村顕史

HIV感染症とAIDSの治療 5 巻 ( 1 ) 頁： 46 - 48 2014年

[Necrotizing fasciitis after a cat bite: a case report].

Hosoda T, Yanagisawa N, Morioka H, Suganuma A, Imamura A, Ajisawa A

Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases 87 巻 ( 2 ) 頁： 211 - 4 2013年3月

掲載種別：研究論文（学術雑誌）出版者・発行元：一般社団法人日本感染症学会

We report on a previously healthy 56-year-old woman who was referred to our hospital with fever and progressive left foot pain. She had been bitten by a cat 7 days previously, and cephalosporins had been prescribed for treatment. However, her clinical symptoms deteriorated, and physical examination on admission was compatible with necrotizing fasciitis. Treatment with ampicillin-sulbactam and clindamycin was initiated. In addition, immediate surgical debridement was performed, resulting in therapeutic success. Culture of the necrotizing tissue grew multiple organisms, including Pasteurella multocida and Bacteroides caccae. Administration of appropriate antibiotics after a cat bite is essential for the prevention of potentially fatal complications.

DOI： 10.11150/kansenshogakuzasshi.87.211

Bilateral Emphysematous Pyelonephritis with a Splenic Abscess

Re-expansion pulmonary edema: evaluation of risk factors in 173 episodes of spontaneous pneumothorax. 国際誌

Morioka H, Takada K, Matsumoto S, Kojima E, Iwata S, Okachi S

Respiratory investigation 51 巻 ( 1 ) 頁： 35 - 9 2013年3月

Morioka Hiroshi, Yanagisawa Naoki, Suganuma Akihiko, Imamura Akifumi, Ajisawa Atsushi

INTERNAL MEDICINE 52 巻 ( 1 ) 頁： 147 - 150 2013年

掲載種別：研究論文（学術雑誌）出版者・発行元：一般社団法人日本内科学会

The case of a 66-year-old woman with untreated diabetes mellitus who was admitted to our hospital with a fever, hypotension and an altered mental status is herein reported. Computed tomography revealed bilateral emphysematous pyelonephritis along with a splenic abscess. Blood and urine cultures grew Escherichia coli. Treatment with systemic antibiotics combined with the insertion of percutaneous and renoureteral catheters was successful. The patient was discharged and completed treatment without developing any subsequent complications.

DOI： 10.2169/internalmedicine.52.8302