研究者詳細 - 中西　啓介

論文 - 中西　啓介

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Exploring Indicators of Subcutaneous Tissue Fluid Accumulation in Breast Cancer-Related Lymphedema Patients Using Fractal Analysis with Virtual Volume 査読有り Open Access

Niwa, S; Hisano, F; Mawaki, A; Nakanishi, K; Watanabe, S; Fukuyama, A; Kikumori, T; Shimamoto, K; Imai, K; Fujimoto, E; Oshima, C

LYMPHATIC RESEARCH AND BIOLOGY 21 巻 ( 5 ) 頁： 432 - 438 2023年5月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Lymphatic Research and Biology

Background: Breast cancer treatment sometimes causes a chronic swelling of the arm called breast cancer-related lymphedema (BCRL). Its progression is believed to be irreversible and is accompanied by tissue fibrosis and lipidosis, so preventing lymphedema from progressing by appropriate intervention at the site of fluid accumulation at an early stage is crucial. The tissue structure can be evaluated in real time by ultrasonography, and this study aims at assessing the ability of fractal analysis using virtual volume in detecting fluid accumulation within BCRL subcutaneous tissue via ultrasound imaging. Methods and Results: We worked with 21 women who developed BCRL (International Society of Lymphology stage II) after unilateral breast cancer treatment. Their subcutaneous tissues were scanned with an ultrasound system (Sonosite Edge II; Sonosite, Inc., FUJIFILM) using a 6- to 15-MHz linear transducer. Then, a 3-Tesla MR system was used to confirm fluid accumulation in the corresponding area of the ultrasound system. Significant differences in both H + 2 and complexity were observed among the three groups (with hyperintense area, without hyperintense area, and unaffected side) (p < 0.05). Post hoc analysis (Mann–Whitney U test; Bonferroni correction p < 0.0167) revealed a significant difference for ‘‘complexity.’’ The evaluation of the distribution in Euclidean space showed that the variation of the distribution decreased in the order of unaffected, without hyperintense area, and with hyperintense area. Conclusion: The ‘‘complexity’’ of the fractal using virtual volume seems to be an effective indicator of the presence or absence of subcutaneous tissue fluid accumulation in BCRL.

DOI： 10.1089/lrb.2022.0062

その他リンク： https://www.liebertpub.com/doi/pdf/10.1089/lrb.2022.0062

A Pilot Study of Determining the Reliability of a New Three-Dimensional Scanning System for Measuring Truncal Thickness After Breast Cancer Surgery 査読有り国際誌

Hisano Fumiya, Watanabe Sachiyo, Niwa Shiori, Nakanishi Keisuke, Mawaki Ayana, Takeno Yukari, Murota Kaoru, Honda Ikumi, Fujimoto Etsuko, Oshima Chika

LYMPHATIC RESEARCH AND BIOLOGY 2022年9月

Prevalence of Metabolic Syndrome and Its Components in Urban Cambodia: A Cross-Sectional Study 査読有り Open Access

Tamaoki, M; Honda, I; Nakanishi, K; Cheam, S; Okawada, M; Sakakibara, H

JOURNAL OF EPIDEMIOLOGY AND GLOBAL HEALTH 12 巻 ( 3 ) 頁： 224 - 231 2022年8月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Journal of Epidemiology and Global Health

Background: The incidence of noncommunicable diseases, such as cardiovascular diseases and diabetes mellitus, is increasing in Cambodia. Urbanization and lifestyle changes due to rapid economic development have affected the components of metabolic syndrome (MetS). This study aimed to determine the prevalence of MetS, MetS components, and health status among Cambodians living in urban areas. Methods: This cross-sectional study enrolled adult Cambodians (age ≥ 20 years) who underwent a health checkup at a Japanese hospital in Phnom Penh. MetS was defined based on the harmonized diagnostic definition from the joint interim statement. Results: Among the 6090 (3174 men and 2916 women) participants who were enrolled in the study, the prevalence of MetS was 60.1% in men and 52.4% in women. The prevalence of elevated blood pressure was 73.2% in men and 65.3% in women, and was the highest MetS component in both men and women. In contrast, the lowest prevalence rates were observed for abdominal obesity (44.8%) in men and for high triglyceride levels (33.5%) in women. The MetS group showed a significantly higher proportion of patients with hypertension, diabetes, dyslipidemia, and obesity compared with the non-MetS group. Conclusion: The high prevalence of MetS in this study was attributed to urbanization, as in economically developed countries. It is necessary to explore the lifestyle habits of Cambodians that contribute to MetS and to develop preventive measures to reduce the incidence and prevalence of MetS.

DOI： 10.1007/s44197-022-00053-5

その他リンク： https://link.springer.com/article/10.1007/s44197-022-00053-5/fulltext.html

An Educator's Growth as a Nursing Preceptor:A Modified Grounded Theory Approach 査読有り

H.Onbe, K.Nakanishi, C.Yamazaki, S Tanifuji, H Arai

The Kitakanto Medical Journal 72 巻 ( 3 ) 頁： 263 - 270 2022年8月

Lifestyle Factors Associated with Metabolic Syndrome in Urban Cambodia 査読有り国際共著国際誌 Open Access

Miharu Tamaoki, Ikumi Honda, Keisuke Nakanishi, Maki Nakajima, Sophathya Cheam, Manabu Okawada, Hisataka Sakakibara

Int. J. Environ. Res. Public Health 19 巻 ( 10481 ) 頁： 10481 - 10481 2022年8月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：International Journal of Environmental Research and Public Health

This study aimed to identify lifestyle factors associated with metabolic syndrome (MetS) in urban Cambodia. In this cross-sectional study, we used existing health checkup data from a private hospital in Phnom Penh, Cambodia. The participants comprised 5459 Cambodians aged ≥20 years who underwent health checkups between 2017 and 2019. The harmonized diagnostic definition was used as the MetS criteria. The prevalence of MetS was 56.6% overall, 60.4% in men and 52.6% in women. The lifestyle factor significantly associated with MetS in both sexes were “eating quicker than others”, (men: odds ratio [OR]= 2.25, 95% confidence interval [CI] = 1.68–3.03, women: OR = 1.92, 95%CI = 1.41–2.60), “walking faster than others”, (men: OR = 0.78, 95% CI = 0.67–0.92, women: OR = 0.75, 95% CI = 0.62–0.89) and “drinking alcohol” (men: OR = 1.33, 95% CI = 1.10–1.61, women: OR = 1.33, 95% CI = 1.09–1.62). Other significant associations with MetS for men was “eating speed is normal”, (OR = 1.73, 95%CI = 1.30–2.31), and, for women, “eating food after dinner at least 3 days a week”, (OR = 1.25, 95%CI = 1.01–1.55), “skipping breakfast at least 3 days a week”, (OR = 0.83, 95%CI = 0.69–0.99) and “getting enough rest from sleep” (OR = 1.19, 95% CI = 1.01–1.42) were significantly associated with MetS. Lifestyle interventions through health education and guidance may be effective in preventing MetS in Cambodia.

DOI： 10.3390/ijerph191710481

Abdominal Obesity and Related Lifestyle Factors Among Cambodians Living in Urban Areas: A Cross-sectional Study 査読有り国際共著国際誌

Tamaoki, Miharu, Honda, Ikumi, Nakanishi, Keisuke, Takehara, Kimie, Doi, Tomoko, Cheam, Sophathya, Okawada, Manabu, Sakakibara, Hisataka

Asia-Pacific Academic Consortium for Public Health (APACPH) 2022年

中小規模病院における病棟看護師の退院支援の実践内容査読有り

恩幣宏美, 中西啓介, 佐名木勇, 小林寛子

日本在宅ケア学会誌 26 巻 ( 1 ) 頁： 83 - 92 2022年

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：一般社団法人日本在宅ケア学会

研究目的は中小規模病院における病棟看護師の退院支援の実践内容を明らかにし，課題を明確にすることである．病棟看護師13名に半構造化面接を実施し，質的帰納的に分析した．実践内容は【患者の強みを活かしたモチベーション向上への働きかけ】【患者・家族と看護師間の良好な関係性の維持に向けた配慮】【退院後の療養行動の安全・維持・実行可能を重視した関わり】【現状と退院後の生活を患者・家族に直視してもらう働きかけ】【退院という生活上の通過点を意識した患者・家族との妥協点の調整】【組織の事情を反映しつつ，患者・家族との一致点を調整】【看護師の専門性を活かして多職種間でリーダーシップを行使する】【多職種間の支援体制の維持・強化にむけたチームマネジメント】であった．看護師は患者・家族の意思決定支援と多職種間のチームマネジメントを実践していたが，自律的な退院支援に向けて看護管理者の実践評価及び承認が重要である．

DOI： 10.60272/jjahc.26.1_83

CiNii Research

Prediction of the Presence of Fluid Accumulation in the Subcutaneous Tissue in BCRL Using Texture Analysis of Ultrasound Images 査読有り国際誌

Niwa, S; Mawaki, A; Hisano, F; Nakanishi, K; Watanabe, S; Fukuyama, A; Kikumori, T; Shimamoto, K; Fujimoto, E; Oshima, C

LYMPHATIC RESEARCH AND BIOLOGY 20 巻 ( 1 ) 頁： 11 - 16 2021年2月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Lymphatic Research and Biology

Background: Breast cancer-related lymphedema (BCRL) is a chronic swelling of the arm due to breast cancer treatment. Lymphedema is diagnosed and staged on the basis of limb circumference measurements and the patient’s subjective symptoms, which have poor reproducibility and objectivity: these cannot detect any fluid accumulation in the tissue. Ultrasonography is a feasible noninvasive technique that can be used to evaluate tissue structure in real time. This study aimed to assess the ability of texture features for discriminating the presence of accumulated fluid within the subcutaneous tissue of BCRL using ultrasound (US) imaging. Methods and Results: This study included 20 women who were treated for unilateral breast cancer and who subsequently developed BCRL (International Society of Lymphology stage II). Subcutaneous tissue was scanned through an US system (Sonosite Edge II; Sonosite, Inc., FUJIFILM) using a 6- to 15-MHz linear transducer to assess the ability of texture features for discriminating the presence of accumulated fluid within the subcutaneous tissue of BCRL. Fluid accumulation was observed using a 3-Tesla MR system under double-echo steady-state conditions. There was a significant difference among the three groups (with hyperintense area, without hyperintense area, and unaffected side) in 11 of 14 textural features (p < 0.05). Post hoc analysis (Mann–Whitney U test; Bonferroni correction p < 0.0167) revealed significant differences in seven textural features within the hyperintense area. Conclusions: This study revealed that seven texture features quantified by US imaging data can provide information regarding fluid accumulation in the subcutaneous tissue of lymphedema.

DOI： 10.1089/lrb.2020.0121

その他リンク： https://www.liebertpub.com/doi/pdf/10.1089/lrb.2020.0121

The Correlation Between Fluid Distribution and Swelling or Subjective Symptoms of the Trunk in Lymphedema Patients: A Preliminary Observational Study 査読有り国際誌 Open Access

Hisano, F; Niwa, S; Nakanishi, K; Mawaki, A; Murota, K; Fukuyama, A; Takeno, Y; Watanabe, S; Fujimoto, E; Oshima, C

LYMPHATIC RESEARCH AND BIOLOGY 19 巻 ( 3 ) 頁： 269 - 273 2020年11月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Lymphatic Research and Biology

Background: Manual lymph drainage (MLD) is one of the common treatments for breast cancer-related lymphedema (BCRL). Although the primary goal of MLD is to drain the excessive fluid accumulated in the affected upper limb and trunk to an area of the body that drains usually, the use of MLD is decided based on swelling and subjective symptoms, without assessing whether there is fluid accumulated in the affected region. The purpose of this study was to examine truncal fluid distribution in a sample of BCRL patients and investigate any correlation between such fluid distribution and swelling or subjective symptoms. Methods and Results: An observational study was conducted with 13 women who had unilateral, upper extremity BCRL. Fluid distribution was evaluated by using two magnetic resonance imaging (MRI) sequences: half-Fourier acquisition single-shot turbo spin echo and three-dimensional double-echo steady-state. The presence of swelling was determined by lymphedema therapists, and subjective symptoms were measured by using a visual analog scale. On MRI, no participants had any free water signals in the trunk. However, seven had swelling and all 13 had some kind of subjective symptoms on the affected side of their trunk. Conclusions: These results suggest that swelling and subjective symptoms do not correlate with the presence of truncal fluid. For such cases, a different approach than MLD may be needed to address truncal swelling and related subjective symptoms. Checking for the presence of fluid in the truncal region may help MLD be used more appropriately.

添付ファイル： The Correlation Between Fluid Distribution and Swelling or Subjective Symptoms of the Trunk in Lymphedema Patients.pdf

DOI： 10.1089/lrb.2020.0075

Nursing activities at clinics in rural areas in Japan: gaps between recognition of importance and implementation 査読有り

Tateishi, M; Nakanishi, K; Takehara, K; Honda, I; Yamauchi, T

NAGOYA JOURNAL OF MEDICAL SCIENCE 82 巻 ( 2 ) 頁： 251 - 260 2020年5月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Nagoya Journal of Medical Science

This study determined the level of implementation and the importance placed on various nursing activities at clinics in rural areas of Japan in order to explore the achievement and perceived importance of implementing certain nursing roles and activities at such clinics. To identify these items, a questionnaire was administered to 40 nurses working in rural clinics. The results showed that activities related to "Basic Nursing Practice" and "Community Understanding" were recognized as important and were performed by almost all nurses. Some activities related to "Administration and Operation" and "Cooperation with Local Government" were recognized as important, but were not implemented, thereby hampering the continuum of care across the health system. These activities, which are related to collaboration with hospitals and local governments that support the clinics, included adjustment of staff inside and outside the facilities to guarantee the use of paid holidays, as well as collaboration with acute care, remote medical systems, and local governments during emergencies and for disaster preparation. Additional support for nurses in collaboration between clinics in rural areas, hospitals, and regional administrations that support the clinics remains a challenge to be addressed.

添付ファイル： Nursing activities at clinics in rural areas in Japan gaps between recognition of importance and implementation.pdf

DOI： 10.18999/nagjms.82.2.251

Breast Cancer-related Lymphedema with the presence or absence of accumulation of Fluid: MR Findings in ISL Stage II Cases 査読有り

Shiori Niwa, Ayana Mawaki, Keisuke Nakanishi, Fumiya Hisano, Yukari Takeno, Atsushi Fukuyama, Toyone Kikumori, Kazuhiro Shimamoto, Etsuko Fujimoto, Chika Oshima

Structure and Function 18 巻 ( 2 ) 頁： 88 - 94 2020年3月

重度に至っていない視力障害を自覚する糖尿病透析患者の食事・水分・体重管理に関するセルフマネジメントの影響要因

恩幣宏美, 山崎千穂, 中西啓介, 島田美樹子, 佐名木勇

腎と透析 87 巻 ( 2 ) 頁： 361 - 366 2019年8月

上肢リンパ浮腫における水分の分布 ― MR 画像を用いて ― 査読有り

鈴木由依子, 間脇彩奈, 中西啓介, 菊森豊根, 竹野ゆかり, 大島千佳, 藤本悦子

形態・機能 16 巻 ( 2 ) 頁： 83-89 2018年

記述言語：英語掲載種別：研究論文（学術雑誌）

リンパ浮腫の効果的なケアを検討するために、MRIを用いて浮腫肢全体の水分分布を調べた。乳がん術後に片側性のリンパ浮腫を発症した７人の女性（平均55.9±13.6歳）の上肢を、MRIを用いて観察した。分析はMR画像（T1強調、T2強調、脂肪抑制、水抑制）から水分貯留部位を同定し、またその面積を画像毎に計算して量の指標とした。脂肪抑制画像（STIR）では、７人の被験者全員の前腕尺側約1/2に高信号（自由水示す）が認められた。この部位は、水抑制画像（FLAIR）では低信号を示した。上腕では５人の被験者の後上腕部に高信号が見られた。腋窩に高信号の見られたものはいなかった。手や指では、STIR上の高信号はいずれも背側で認められた。量の解析では自由水は前腕尺側に多いことが明らかになった。これらのことから、複合的治療を構成するリンパドレナージの対象部位として、前腕尺側が最も重要であることが示唆される。

DOI： 10.11172/keitaikinou.16.83

LONG-TERM FOLLOW-UP OF COLLATERAL PATHWAYS ESTABLISHED AFTER LYMPHADENECTOMY IN RATS 査読有り

Takeno, Y; Arita, H; Oshima, C; Mawaki, A; Nakanishi, K; Kurono, F; Fujimoto, E

LYMPHOLOGY 50 巻 ( 3 ) 頁： 131 - 135 2017年9月

Nighttime Bandaging to Reduce Lymphedema Swelling A Clinical Pre-Post Study 査読有り

Nakanishi Keisuke, Mawaki Ayana, Oshima Chika, Takeno Yukari, Kurono Fumiya, Taniho Yuiko, Murotani Kenta, Kikumori Toyone, and Fujimoto Etsuko

SAGE Open Nursing 3 巻頁： 1-8 2017年

Importance of cystatin C and uric acid levels in the association of cardiometabolic risk factors in Japanese junior high school students. 査読有り

Harada M, Izawa A, Hidaka H, Nakanishi K, Terasawa F, Motoki H, Yazaki Y, Ikeda U, Hongo M, Study Project on Prevention of Metabolic Syndrome among Children,Adolescents,and Young Adults in Shinshu

Journal of cardiology 頁： - 2016年4月

植込み型除細動器（ICD）を移植した壮年期患者がICDとともに生きるプロセス査読有り

中西啓介, 岡美智代, 富田威

日本看護科学学会 34 巻 ( 1 ) 頁： 311-320 2014年

Serum High-density Lipoprotein Cholesterol Level and Lifestyle Habits among Japanese Junior High School Students 査読有り

Hongo Minoru, Hidaka Hiroya, SakaguchI Shigeko, NAKANISHI Keisuke, TERASAWA Fumiko, ICHIKAWA Motoki, HIROTA Naoko, TSURUTA Goro, TANAKA Naoki, IZAWA Atsushi, YAZAKI Yoshikazu, IKEDA Uichi, KOIKE Kenichi

信州医学雑誌 = The Shinshu medical journal 61 巻 ( 4 ) 頁： 205-215 2013年

Association between serum uric acid levels and cardiometabolic risk factors among Japanese junior high school students. 査読有り

Hongo M, Hidaka H, Sakaguchi S, Nakanishi K, Ichikawa M, Hirota N, Tanaka N, Tsuruta G, Yazaki Y, Kinoshita O, Ikeda U, Koike K, Investigators of Study Project on Prevention of Metabolic Syndrome among Children,Adolescents,and Young Adults in Shinshu

Circulation journal : official journal of the Japanese Circulation Society 74 巻頁： 1570-1577 2010年8月

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