記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Frontiers in Cell and Developmental Biology  

Faithful chromosome segregation is crucial for cell division in eukaryotes, facilitated by the kinetochore, a multi-subunit protein complex that connects chromosomes to the spindle microtubules. Recent research has significantly advanced our understanding of kinetochore function in plants, including surprising findings about spindle assembly checkpoint, the composition of the inner kinetochore and unique kinetochore arrangement in holocentric Cuscuta species. Additionally, some kinetochore proteins in plants have been implicated in roles beyond chromosome segregation, such as cytokinesis regulation and involvement in developmental processes. This review summarizes recent insights into plant kinetochore biology, compares plant kinetochores with those of animals and fungi, and highlights key open questions and potential future directions in the field.

DOI： 10.3389/fcell.2024.1510019

Open Access

Web of Science

Scopus

PubMed

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Cytoskeleton  

Microtubules (MTs) are essential cytoskeletal elements in all eukaryotes, playing critical roles in cell shape, intercellular organization, cell division, and cell motility. The organization of the MT network has undergone significant changes throughout plant evolution. Some MT structures, such as the preprophase band and phragmoplast, are innovations in plant lineages, while others, including the centriole and flagellum, have been lost over time. Bryophytes, consisting of mosses, liverworts, and hornworts, are the earliest land plants and occupy a key phylogenetic position in the evolution of MT organization. In the past two decades, advances in genomics, genetics, and cell imaging technologies have significantly enhanced our understanding of MT organization and function. Two representative species, Physcomitrium patens (moss) and Marchantia polymorph (liverwort), have become established model organisms, and new models for hornworts are emerging. In this review, we summarize the current knowledge of the MT cytoskeleton, drawing from early electron microscopy studies and recent advances in these emerging models. Our aim is to provide a comprehensive overview of the major MT array types and key factors involved in MT organization in bryophytes, offering insights into MT adaptation during plant evolution.

DOI： 10.1002/cm.22009

Scopus

PubMed

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（国際会議プロシーディングス）  

DOI： 10.1038/s41467-022-30239-1

Web of Science

記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1093/pcp/pcab067

Web of Science

担当区分：筆頭著者   記述言語：英語  

DOI： 10.1093/pcp/pcw030

記述言語：英語 著書種別：学術書

DOI： https://doi.org/10.1007/978-1-0716-2867-6_11

開催年月日： 2023年10月

記述言語：英語   会議種別：口頭発表（一般）  

開催年月日： 2023年9月

記述言語：英語   会議種別：口頭発表（一般）