Updated on 2024/03/28

写真a

 
MURAYAMA Keiji
 
Organization
Graduate School of Engineering Biomolecular Engineering 1 Assistant Professor
Graduate School
Graduate School of Engineering
Undergraduate School
School of Engineering Chemistry and Biotechnology
Title
Assistant Professor
External link

Degree 1

  1. 博士(工学) ( 2015.3   名古屋大学 ) 

Research Interests 5

  1. 分子ロボティクス

  2. 光応答性

  3. 人工核酸

  4. ケミカルライゲーション

  5. XNA

Research Areas 3

  1. Natural Science / Biophysics, chemical physics and soft matter physics

  2. Life Science / Bioorganic chemistry

  3. Nanotechnology/Materials / Chemical biology

Current Research Project and SDGs 3

  1. 化学ライゲーションを利用した人工生命・原始生命に関する研究

  2. 人工核酸を利用した高機能ツールの開発

  3. 新規人工核酸XNAの開発

Research History 3

  1. Nagoya University   Institute of Innovation for Future Society   Assistant Professor

    2020.1

  2. Nagoya University   Assistant Professor

    2016.2

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  3. 名古屋大学ベンチャー・ビジネス・ラボラトリー 中核的研究機関研究員   研究員

    2015.4 - 2016.1

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    Country:Japan

Education 2

  1. Nagoya University   Graduate School, Division of Engineering

    - 2015.3

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    Country: Japan

  2. Nagoya University   Faculty of Engineering

    - 2010.3

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    Country: Japan

Professional Memberships 4

  1. 高分子学会   会員

  2. 日本化学会   会員

  3. 光化学協会   会員

  4. 日本核酸化学会

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Committee Memberships 4

  1. 高分子学会東海支部 東海高分子研究会   庶務幹事  

    2022.4 - 2023.3   

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    Committee type:Academic society

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  2. 高分子学会東海支部 東海高分子研究会   4月講演会幹事  

    2021.4 - 2022.3   

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    Committee type:Academic society

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  3. 高分子学会東海支部 東海高分子研究会   夏期合宿幹事  

    2018.4 - 2019.3   

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    Committee type:Academic society

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  4. 高分子学会東海支部 東海高分子研究会   12月講演会幹事  

    2017.4 - 2018.3   

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    Committee type:Academic society

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Awards 6

  1. 令和5年度「赤﨑賞」

    2024.3   新規非環状型人工核酸XNAを利用した高機能分子ツール・人工生命システム構築

  2. 第72回進歩賞

    2023.3   公益社団法人日本化学会  

    村山恵司

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  3. 2020年度高分子研究奨励賞

    2021   公益社団法人 高分子学会  

  4. ISNAC 2019, 若手優秀講演賞(大塚賞)

    2019.10  

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    Award type:Award from international society, conference, symposium, etc.  Country:Japan

  5. 第13回バイオ関連化学シンポジウム, 講演賞

    2019.9   日本化学会  

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    Award type:Award from Japanese society, conference, symposium, etc.  Country:Japan

  6. 第26回バイオ・高分子シンポジウム, 若手研究者奨励講演賞

    2016.7   公益社団法人 高分子学会 バイオ・高分子研究会  

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    Award type:Award from Japanese society, conference, symposium, etc.  Country:Japan

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Papers 47

  1. Nonenzymatic polymerase-like template-directed synthesis of acyclic l-threoninol nucleic acid Reviewed

    Murayama Keiji, Okita Hikari, Kuriki Takumi, Asanuma Hiroyuki

    NATURE COMMUNICATIONS   Vol. 12 ( 1 )   2021.2

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41467-021-21128-0

    Web of Science

  2. DNA Reaction System That Acquires Classical Conditioning Reviewed International coauthorship

    Nakakuki, T; Toyonari, M; Aso, K; Murayama, K; Asanuma, H; de Greef, TFA

    ACS SYNTHETIC BIOLOGY   Vol. 13 ( 2 ) page: 521 - 529   2024.1

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  3. Highly Functional Acyclic Xeno Nucleic Acids Invited Reviewed

    Murayama, K; Okita, H; Asanuma, H

    BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN   Vol. 96 ( 10 ) page: 1179 - 1187   2023.10

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    Authorship:Lead author, Corresponding author   Language:English  

    DOI: 10.1246/bcsj.20230188

    Web of Science

  4. Rapid Chemical Ligation of DNA and Acyclic Threoninol Nucleic Acid (aTNA) for Effective Nonenzymatic Primer Extension Reviewed

    Hikari Okita, Shuto Kondo, Keiji Murayama, Hiroyuki Asanuma

    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY   Vol. 145 ( 32 ) page: 17872 - 17880   2023.7

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:AMER CHEMICAL SOC  

    Previously, nonenzymatic primer extension reaction of acyclic l-threoninol nucleic acid (L-aTNA) wasachieved in the presence of N-cyanoimidazole (CNIm)and Mn2+; however, the reaction conditions were not optimizedand a mechanistic insight was not sufficient. Herein, we report investigationof the kinetics and reaction mechanism of the chemical ligation ofL-aTNA to L-aTNA and of DNA to DNA.We found that Cd2+, Ni2+, and Co2+ accelerated ligation of both L-aTNA and DNA and that the rate-determining step was activationof the phosphate group. The activation was enhanced by duplex formationbetween a phosphorylated L-aTNA fragment and template,resulting in unexpectedly more effective L-aTNA ligationthan DNA ligation. Under optimized conditions, an 8-mer L-aTNA primer could be elongated by ligation to L-aTNA trimers to produce a 29-mer full-length oligomer with60% yield within 2 h at 4 & DEG;C. This highly effective chemicalligation system will allow construction of artificial genomes, robustDNA nanostructures, and xeno nucleic acids for use in selection methods.Our findings also shed light on the possible pre-RNA world.

    DOI: 10.1021/jacs.3c04979

    Web of Science

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  5. Functionalization of acyclic xenonucleic acid with modified nucleobases Invited Reviewed

    Keiji Murayama, Yuuhei Yamano, Hiroyuki Asanuma

    Polymer Journal   Vol. 55 ( 7 ) page: 743 - 752   2023.7

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:Springer Science and Business Media LLC  

    DOI: 10.1038/s41428-023-00776-7

    Web of Science

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    Other Link: https://www.nature.com/articles/s41428-023-00776-7

  6. Kinesin motors driven microtubule swarming triggered by UV light Reviewed

    Ishii Satsuki, Akter Mousumi, Murayama Keiji, Kabir Arif Md Rashedul, Asanuma Hiroyuki, Sada Kazuki, Kakugo Akira

    POLYMER JOURNAL   Vol. 54 ( 12 ) page: 1501 - 1507   2022.12

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  7. DNA Concentration Regulator That can be Driven for a Long Time Reviewed

    Nakakuki Takashi, Murayama Keiji, Asanuma Hiroyuki

    NEW GENERATION COMPUTING   Vol. 40 ( 2 ) page: 681 - 702   2022.7

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  8. Orthogonal Amplification Circuits Composed of Acyclic NucleicAcids Enable RNA Detection br Reviewed

    Chen Yanglingzhi, Nagao Ryuya, Murayama Keiji, Asanuma Hiroyuki

    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY   Vol. 144 ( 13 ) page: 5887 - 5892   2022.4

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    Authorship:Lead author, Corresponding author   Language:English  

    DOI: 10.1021/jacs.1c12659

    Web of Science

  9. Methyl group configuration on acyclic threoninol nucleic acids (aTNAs) impacts supramolecular properties Reviewed

    Murayama Keiji, Kashida Hiromu, Asanuma Hiroyuki

    ORGANIC & BIOMOLECULAR CHEMISTRY     2022.3

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    Authorship:Lead author, Corresponding author   Language:English  

    DOI: 10.1039/d2ob00266c

    Web of Science

  10. Unexpected Dissociation of Photoresponsive UV-ON DNA Carrying p-tert-Butyl Azobenzene under UV Light Irradiation Reviewed

    Ishii Satsuki, Murayama Keiji, Sada Kazuki, Asanuma Hiroyuki, Kakugo Akira

    CHEMISTRY LETTERS   Vol. 51 ( 3 ) page: 292 - 295   2022.3

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    Authorship:Lead author   Language:English  

    DOI: 10.1246/cl.210788

    Web of Science

  11. Signal Amplification Circuit Composed of Serinol Nucleic Acid for RNA Detection Reviewed

    Chen Yanglingzhi, Murayama Keiji, Asanuma Hiroyuki

    CHEMISTRY LETTERS   Vol. 51 ( 3 ) page: 330 - 333   2022.3

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    Authorship:Corresponding author   Language:English  

    DOI: 10.1246/cl.210813

    Web of Science

  12. Renewable DNA Proportional-Integral Controller with Photoresponsive Molecules

    Tamba Masaaki, Murayama Keiji, Asanuma Hiroyuki, Nakakuki Takashi

    MICROMACHINES   Vol. 13 ( 2 )   2022.2

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    Language:Japanese  

    DOI: 10.3390/mi13020193

    Web of Science

  13. Xeno nucleic acids (XNAs) having non-ribose scaffolds with unique supramolecular properties Invited Reviewed

    Asanuma Hiroyuki, Kamiya Yukiko, Kashida Hiromu, Murayama Keiji

    CHEMICAL COMMUNICATIONS     2022.1

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    Language:English  

    DOI: 10.1039/d1cc05868a

    Web of Science

  14. A Pyrene-Modified Serinol Nucleic Acid Nanostructure Converts the Chirality of Threoninol Nucleic Acids into Circularly Polarized Luminescence Signals Reviewed

    Kashida Hiromu, Nishikawa Keiji, Ito Yuka, Murayama Keiji, Hayashi Ichiyo, Kakuta Takahiro, Ogoshi Tomoki, Asanuma Hiroyuki

    CHEMISTRY-A EUROPEAN JOURNAL   Vol. 27 ( 59 ) page: 14582 - 14585   2021.10

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    Language:English  

    DOI: 10.1002/chem.202102333

    Web of Science

  15. RNA以前に非環状型XNAがPre-RNAとして存在したか? Invited

    浅沼 浩之, 沖田 ひかり, 村山 恵司

      Vol. 49   page: 9   2021.9

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    Language:Japanese  

  16. Design and Hybridization Properties of Acyclic Xeno Nucleic Acid Oligomers Reviewed

    Murayama Keiji, Asanuma Hiroyuki

    CHEMBIOCHEM   Vol. 22 ( 15 ) page: 2507 - 2515   2021.8

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    Authorship:Lead author, Corresponding author   Language:English  

    DOI: 10.1002/cbic.202100184

    Web of Science

  17. Dual Crosslinking Photo-Switches for Orthogonal Photo-Control of Hybridization Between Serinol Nucleic Acid and RNA Reviewed

    Yamano Yuuhei, Murayama Keiji, Asanuma Hiroyuki

    Dual Crosslinking Photo-Switches for Orthogonal Photo-Control of Hybridization Between Serinol Nucleic Acid and RNA   Vol. 27 ( 14 ) page: 4599 - 4604   2021.3

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/chem.202003528

    Web of Science

  18. Light-Regulated Liquid-Liquid Phase Separation for Spatiotemporal Protein Recruitment and Cell Aggregation Reviewed

    Light-Regulated Liquid-Liquid Phase Separation for Spatiotemporal Protein Recruitment and Cell Aggregation

    Light-Regulated Liquid-Liquid Phase Separation for Spatiotemporal Protein Recruitment and Cell Aggregation   Vol. 13 ( 4 ) page: 5652 - 5659   2021.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acsami.0c22314

    Web of Science

  19. Intrastrand backbone-nucleobase interactions stabilize unwound right-handed helical structures of heteroduplexes of L-aTNA/RNA and SNA/RNA Reviewed

    Kamiya Yukiko, Satoh Tadashi, Kodama Atsuji, Suzuki Tatsuya, Murayama Keiji, Kashida Hiromu, Uchiyama Susumu, Kato Koichi, Asanuma Hiroyuki

    COMMUNICATIONS CHEMISTRY   Vol. 3 ( 1 )   2020.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s42004-020-00400-2

    Web of Science

  20. Photo-regulated trajectories of gliding microtubules conjugated with DNA Reviewed

    Akter Mousumi, Keya Jakia Jannat, Kabir Arif Md Rashedul, Asanuma Hiroyuki, Murayama Keiji, Sada Kazuki, Kakugo Akira

    CHEMICAL COMMUNICATIONS   Vol. 56 ( 57 ) page: 7953 - 7956   2020.7

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1039/d0cc03124k

    Web of Science

  21. A triplex-forming linear probe for sequence-specific detection of duplex DNA with high sensitivity and affinity Reviewed

    Chen Yanglingzhi, Murayama Keiji, Kashida Hiromu, Kamiya Yukiko, Asanuma Hiroyuki

    CHEMICAL COMMUNICATIONS   Vol. 56 ( 40 ) page: 5358 - 5361   2020.5

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1039/d0cc01865a

    Web of Science

  22. Incorporation of Pseudo-complementary Bases 2,6-Diaminopurine and 2-Thiouracil into Serinol Nucleic Acid (SNA) to Promote SNA/RNA Hybridization Reviewed

    Kamiya Yukiko, Sato Fuminori, Murayama Keiji, Kodama Atsuji, Uchiyama Susumu, Asanuma Hiroyuki

    CHEMISTRY-AN ASIAN JOURNAL   Vol. 15 ( 8 ) page: 1266 - 1271   2020.4

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/asia.201901728

    Web of Science

  23. A Quencher-Free Linear Probe from Serinol Nucleic Acid with a Fluorescent Uracil Analogue Reviewed

    Murayama Keiji, Asanuma Hiroyuki

    CHEMBIOCHEM   Vol. 21 ( 1-2 ) page: 120 - 128   2020.1

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/cbic.201900498

    Web of Science

  24. 8-Pyrenylvinyl Adenine Controls Reversible Duplex Formation between Serinol Nucleic Acid and RNA by [2+2] Photocycloaddition Reviewed

    Murayama Keiji, Yamano Yuuhei, Asanuma Hiroyuki

    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY   Vol. 141 ( 24 ) page: 9485 - 9489   2019.6

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/jacs.9b03267

    Web of Science

  25. cis-On/trans-Off of DNA Hybridization with Alkylthio-azobenzene on L-Threoninol Responding to Visible Light

    Asanuma Hiroyuki, Ishikawa Teruchika, Yamano Yuuhei, Murayama Keiji, Liang Xingguo

    CHEMPHOTOCHEM   Vol. 3 ( 6 ) page: 418 - 424   2019.6

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/cptc.201900060

    Web of Science

  26. Orthogonally Photocontrolled Non-Autonomous DNA Walker

    Skugor Marko, Valero Julian, Murayama Keiji, Centola Mathias, Asanuma Hiroyuki, Famulok Michael

    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION   Vol. 58 ( 21 ) page: 6948 - 6951   2019.5

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/anie.201901272

    Web of Science

  27. The Use of Serinol Nucleic Acids as Ultrasensitive Molecular Beacons

    Murayama Keiji, Kashida Hiromu, Asanuma Hiroyuki

    NON-NATURAL NUCLEIC ACIDS: METHODS AND PROTOCOLS   Vol. 1973   page: 261-279   2019

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/978-1-4939-9216-4_17

    Web of Science

  28. The DNA duplex as an aqueous one-dimensional soft crystal scaffold for photochemistry. Invited Reviewed

    Asanuma, H.; Murayama, K.; Kamiya, Y.; Kashida, H.

    Bull. Chem. Soc. Jpn.   Vol. 91   page: 1739-1748   2018.12

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  29. Introduction of 2,6-Diaminopurines into Serinol Nucleic Acid Improves Anti-miRNA Performance

    Kamiya Yukiko, Donoshita Yuka, Kamimoto Hiroshi, Murayama Keiji, Ariyoshi Jumpei, Asanuma Hiroyuki

    CHEMBIOCHEM   Vol. 18 ( 19 ) page: 1917-1922   2017.10

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/cbic.201700272

    Web of Science

  30. D-aTNA Circuit Orthogonal to DNA Can Be Operated by RNA Input via SNA

    Murayama Keiji, Nagao Ryuya, Asanuma Hiroyuki

    CHEMISTRYSELECT   Vol. 2 ( 20 ) page: 5624-5627   2017.7

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/slct.201701126

    Web of Science

  31. Antisense oligonucleotide modified with serinol nucleic acid (SNA) induces exon skipping in mdx myotubes Reviewed

    Le Bao T., Murayama Keiji, Shabanpoor Fazel, Asanuma Hiroyuki, Veedu Rakesh N.

    RSC ADVANCES   Vol. 7 ( 54 ) page: 34049-34052   2017.7

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1039/c7ra06091b

    Web of Science

  32. Design of photofunctional oligonucleotides by copolymerization of natural nucleobases with base surrogates prepared from acyclic scaffolds

    Asanuma Hiroyuki, Murayama Keiji, Kamiya Yukiko, Kashida Hiromu

    POLYMER JOURNAL   Vol. 49 ( 3 ) page: 279 - 289   2017.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/pj.2016.120

    Web of Science

  33. Effect of Methyl Group on Acyclic Serinol Scaffold for Tethering Dyes on the DNA Duplex Stability

    Murayama Keiji, Asanuma Hiroyuki

    CHEMBIOCHEM   Vol. 18 ( 1 ) page: 142-149   2017.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/cbic.201600558

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  34. 天然に存在しない非環状構造の核酸アナログ-人工の非環状骨格で神の設計した環状骨格に挑む

    村山恵司, 浅沼浩之

    化学   Vol. 71 ( 3 ) page: 66-67   2016.3

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    Language:Japanese  

  35. Acyclic artificial nucleic acids with phosphodiester bonds exhibit unique functions Reviewed

    H. Kashida; K. Murayama; H. Asanuma

    Polymer J.   Vol. 48   page: 781-786   2016

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    Language:English  

  36. Strand-invading linear probe combined with unmodified PNA Reviewed

    Aasanuma, H.; Niwa, R.; Akahane, M.; Murayama, K.; Kashida, H.; Kamiya, Y.

    Bioorg. Med. Chem.   Vol. 24   page: 4129-4137   2016

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.bmc.2016.06.055

  37. Visible Light-Triggered Crosslinking of DNA Duplex by Reversible [2+2] Photocycloaddition of Styrylpyrene Reviewed

    Doi, T.; Kawai, H.; Murayama, K.; Kashida, H.; Asanuma, H.

    Chem. Eur. J.   Vol. 22   page: 267-273   2016

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    Language:English   Publishing type:Research paper (scientific journal)  

  38. Azobenzene C-nucleosides for photo-controlled hybridization of DNA at room temperature Reviewed

    Goldau, T.; Murayama, K.; Brieke, C.; Asanuma, H., Heckel, A.

    Chem. Eur. J.     page: 15974-15980   2015

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/chem.201502653

  39. 新規人工核酸SNAを用いたRNAイメージング

    樫田啓, 村山恵司, 浅沼浩之

    生体の科学   Vol. 66 ( 2 ) page: 145-150   2015

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    Language:Japanese  

  40. Reversible photoswitching of RNA hybridization at room temperature with an azobenzene C-nucleoside. Reviewed

    Goldau, T.; Murayama, K.; Brieke, C.; Steinwand, S.; Mondal, P.; Biswas, M.; Burghardt, I.; Wachtveitl, J.; Asanuma, H.; Heckel, A.

    Chem. Eur. J.     page: 6500-6503   2015

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  41. Acyclic L-Threoninol Nucleic Acid (L-aTNA) with Suitable Structural Rigidity Cross-pairs with DNA and RNA. Reviewed

    Murayama, K.; Kashida, H.; Asanuma, H.

    Chem. Commun.     page: 6500-6503   2015

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  42. Ultra-Sensitive Molecular Beacon Designed with Totally Serinol Nucleic Acid (SNA) for Monitoring mRNA in Cell Reviewed

    Murayama, K.; Kamiya, Y.; Kashida, H.; Asanuma, H.

    ChemBioChem     page: 1298-1301   2015

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/cbic.201500167

  43. Enhancement of stability and activity of siRNA by terminal substitution with Serinol Nucleic Acid (SNA) Reviewed

    Kamiya, Y.; Takai, J.; Ito, H.; Murayama, K.; Kashida, H.; Asanuma, H.

    ChemBioChem     page: 2549-2555   2014

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  44. The sugar-deficient G-quadruplex: incorporation of aTNA in quadruplex structures Reviewed

    Zhou, J.; Murayama, K.; Amrane, S.; Kashida, H.; Bourdoncle, A.; Asanuma, H.; Mergny, J. L.

    Chem. Sci.   Vol. 4   page: 3693-3698   2013

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  45. Highly stable duplex formation by artificial nucleic acids aTNA and SNA with acyclic scaffolds Reviewed

    Murayama, K.; Tanaka, Y.; Toda, T.; Kashida, H.; Asanuma, H.

    Chem. Eur. J.   Vol. 19   page: 14151-14158   2013

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  46. Control of the Chirality and Helicity of Oligomers of Serinol Nucleic Acid (SNA) by Sequence Design Reviewed

    Kashida, H.; Murayama, K.; Toda, T.; Asanuma, H.

    Angew. Chem. Int. Ed.   Vol. 50   page: 1285-1288   2011

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    Language:English   Publishing type:Research paper (scientific journal)  

  47. Unexpectedly stable artificial duplex from flexible acyclic threoninol Reviewed

    Asanuma, H.; Toda, T.; Murayama, K.; Liang, X.G.; Kashida, H.

    J. Am. Chem. Soc.   Vol. 132   page: 14702-14703   2010

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    Language:English   Publishing type:Research paper (scientific journal)  

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Books 1

  1. 核酸医薬の創製と応用展開・非環状骨格型人工核酸:aTNA, SNA

    神谷由紀子、村山恵司、樫田 啓、浅沼浩之( Role: Joint author)

    シーエムシー出版  2016 

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    Language:Japanese

MISC 6

  1. RNA以前の世界を妄想する Invited

    浅沼浩之, 村山恵司

    化学と工業   Vol. 75 ( 8 ) page: 552 - 554   2022

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  2. Nonenzymatic Polymerase-Like Primer Extension of Acyclic L-Threoninol Nucleic Acid Invited

    Keiji Murayama

      Vol. 71 ( 6 )   2022

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    Authorship:Lead author, Corresponding author  

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  3. 光駆動型DNAナノマシン Invited

    浅沼浩之, 村山恵司, 神谷由紀子, 樫田 啓

    高分子   Vol. 70   page: 550 - 552   2021

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  4. 光応答性XNA ~アゾベンゼンに頼らない新たな光制御~ Invited

    村山恵司

    日本核酸化学会誌   Vol. 5   page: 2 - 7   2021

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    Authorship:Lead author, Corresponding author  

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  5. 核酸医薬の創製に向けた人工核酸の開発 Invited

    樫田啓, 村山恵司, 浅沼浩之

    バイオマテリアル   Vol. 38 ( 2 ) page: 124 - 129   2020

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  6. 非環状型人工核酸のケミカルライゲーション Invited

    村山恵司

    Newsletter-生体機能関連部会-   Vol. 34   page: 17 - 22   2019

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Presentations 66

  1. 人工生命システム創製を目指した人工核酸XNAの鎖伸長反応の開発 Invited

    村山恵司

    第54回中部化学関係学協会支部連合秋季大会  2023.11.11 

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    Event date: 2023.11

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

  2. 人工生命システム構築に向けた人工核酸XNAの鎖伸長反応 Invited

    村山恵司

    細胞を創る研究会  2023.9.25 

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    Event date: 2023.9

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Venue:東京大学 駒場キャンパス  

  3. Nonenzymatic Primer Extension of Acyclic L-Threoninol Nucleic Acid Using Highly Effective Chemical Ligation Invited International conference

    Keiji Murayama

    ICPAC Bali 2023 

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    Event date: 2023.9

    Presentation type:Oral presentation (invited, special)  

    Venue:Bali/オンライン  

  4. 非環状型人工核酸を利用した多彩な生物学的ツールの創製 Invited

    村山恵司

    日本化学会第103春季年会 

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    Event date: 2023.3

    Presentation type:Oral presentation (invited, special)  

  5. 人工核酸XNAを利用した直交性回路及び鎖連結法の開発

    村山恵司、陳 楊凌志、長尾竜弥、沖田ひかり、近藤修斗、浅沼浩之

    第6回分子ロボティクス年次大会  2022.11.12 

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    Event date: 2022.11

    Language:Japanese   Presentation type:Poster presentation  

  6. 非環状型XNAを利用した機能性ハイドロゲルの開発

    村山恵司、重松勇貴、奥田祐登、浅沼浩之

    第53回 中部化学関係学協会支部連合秋季大会  2022.11.6 

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    Event date: 2022.11

    Language:Japanese   Presentation type:Oral presentation (general)  

  7. 非環状型XNAで構成される直交性シグナル増幅回路の開発とRNA検出への応用

    村山恵司、陳 楊凌志、長尾竜弥、浅沼浩之

    第16回バイオ関連化学シンポジウム   2022.9.12 

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    Event date: 2022.9

    Language:Japanese   Presentation type:Oral presentation (general)  

  8. 非環状型XNAを利用した直交性シグナル増幅回路の開発とRNA検出への応用

    村山恵司、陳 楊凌志、長尾竜弥、浅沼浩之

    第71回高分子討論会  2022.9.5 

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    Event date: 2022.9

    Language:Japanese   Presentation type:Oral presentation (general)  

  9. 人工核酸aTNAを利用した直交性HCRの開発とRNA検出への応用

    村山恵司、陳 楊凌志、長尾竜弥、浅沼浩之

    第32回バイオ・高分子シンポジウム  2022.7.28 

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    Event date: 2022.7

    Language:Japanese   Presentation type:Oral presentation (general)  

  10. DNAおよび人工核酸L-aTNAにおける鋳型特異的ケミカルライゲーションの高速化

    村山恵司, 近藤修斗, 沖田ひかり, 浅沼浩之

    日本化学会第101春季年会 

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    Event date: 2022.3

    Language:Japanese   Presentation type:Oral presentation (general)  

  11. Serinol nucleic acid (SNA) based fluorescent probe for highly sensitive detection of RNA International conference

    Keiji Murayama, Zehua Liu, Hiroyuki Asanuma

    Pacifichem2021 

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    Event date: 2021.12

    Language:English   Presentation type:Poster presentation  

  12. Photoregulation of Artificial Nucleic Acid via Photo-Cycloaddition of Modified Adenine Residues for Chemical AI Invited International conference

    Keiji Murayama, Yuuhei Yamano, Hiroyuki Asanuma

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    Event date: 2021.11

    Language:English   Presentation type:Oral presentation (general)  

  13. Nonenzymatic polymerase-like elongation of acyclic L-threoninol nucleic acid via chemical ligation International conference

    Keiji Murayama, Hikari Okita, Hiroyuki Asanuma

    ISNAC2021 

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    Event date: 2021.11

    Language:English   Presentation type:Oral presentation (general)  

  14. 化学AI構築に向けた光応答性人工核酸の設計と非酵素的鎖伸長反応の開発 Invited

    村山恵司

    「細胞を創る」研究会14.0 

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    Event date: 2021.11

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

  15. 異なる波長で独立に制御可能な光応答性人工核酸の開発

    村山恵司, 山野雄平, 浅沼浩之

    第15回バイオ関連化学シンポジウム  

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    Event date: 2021.9

    Language:Japanese   Presentation type:Oral presentation (general)  

  16. 安定な二重鎖を形成する非環状型人工核酸の設計と高機能化 Invited

    村山恵司

    2021年度 北海道高分子若手研究会  2021.8.27 

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    Event date: 2021.8

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

  17. 非環状型人工核酸の鋳型重合による配列複製と機能化 Invited

    村山恵司

    第70回高分子学会年次大会  2021.5.28 

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    Event date: 2021.5

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

  18. 人工核酸L-aTNAを基にした新たな非環状型人工核酸の合成

    村山恵司, 飯塚洋平, 浅沼浩之

    日本化学会第100春季年会 

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    Event date: 2020.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  19. 非環状型人工核酸の高効率なケミカルライゲーション法

    村山恵司

    核酸化学懇話会2020 北海道・東地区セミナー 

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    Event date: 2020.1

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  20. Photo-control of reversible duplex formation between SNA and RNA by [2+2] photocycloaddition of 8-pyrenylvinyl adenine

    Keiji Murayama, Yuuhei Yamano, Hiroyuki Asanuma

    ISNAC 2019 

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    Event date: 2019.10

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  21. Artificial Nucleic Acids Composed of Acyclic Backbone for Fluorescent Probe and Antisense Reagent International conference

    Keiji Murayama, Hiromu Kashida, Hiroyuki Asanuma

    15th Annual Meeting Of The OTS 

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    Event date: 2019.10

    Language:English   Presentation type:Poster presentation  

    Country:Germany  

  22. 人工核酸オリゴマーを架橋点とする機能性超分子ハイドロゲルの開発

    村山恵司, 重松勇貴, 浅沼浩之

    第68回高分子討論会 

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    Event date: 2019.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  23. 非環状型人工核酸aTNAの高速かつ高効率な鋳型特異的ケミカルライゲーション法の開発

    村山恵司, 栗木琢実, 浅沼浩之

    第13回バイオ関連化学シンポジウム 

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    Event date: 2019.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  24. 非環状型人工核酸オリゴマーを利用した機能性ハイドロゲルの開発

    村山恵司, 重松勇貴, 浅沼浩之

    第29回バイオ・高分子シンポジウム 

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    Event date: 2019.7

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  25. 人工核酸オリゴマーを利用した多機能性超分子ハイドロゲルの開発

    村山恵司, 重松勇貴, 浅沼浩之

    第68回高分子学会年次大会 

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    Event date: 2019.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  26. Development of novel stimuli-responsive supramolecular hydrogel containing artificial nucleic acids

    MURAYAMA, Keiji; SHIGEMATSU, Yuuki; ASANUMA, Hiroyuki

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    Event date: 2019.3

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  27. 色素オリゴマーの二重鎖形成を利用した新規刺激応答性超分子ハイドロゲルの開発

    村山恵司・重松勇貴・浅沼浩之

    第30 回 高分子ゲル研究討論会 

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    Event date: 2019.1

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  28. 蛍光性核酸塩基導入による非環状型人工核酸プローブの開発

    村山恵司, 浅沼浩之

    第67回高分子討論会 

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    Event date: 2018.9

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  29. 光架橋型修飾核酸塩基導入による非環状型人工核酸SNAの光制御

    村山恵司, 山野雄平, 浅沼浩之

    第12回バイオ関連化学シンポジウム 

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    Event date: 2018.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  30. 修飾核酸塩基導入による人工核酸SNAの高機能化

    村山恵司, 山野雄平, 浅沼浩之

    第6回バイオ関連化学シンポジウム若手フォーラム 

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    Event date: 2018.9

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  31. Conversion of light energy into mechanical force by using nucleic acids tetheringphoto-responsive molecules

    Keiji Murayama, Yuuhei Yamano, Hiroyuki Asanuma

    The 79t hOkazaki Conference Synthetic, Biological, and Hybrid Molecular Engines 

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    Event date: 2018.8 - 2018.9

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  32. 非環状型人工核酸aTNAの鋳型特異的ケミカルライゲーション法の開発

    村山恵司, 栗木琢実, 浅沼浩之

    第28回バイオ・高分子シンポジウム 

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    Event date: 2018.7

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  33. Design of novel fluorescent probe with fluorescent nucleobase on artificial acyclic nucleic acid International conference

    Keiji Murayama, Hiroyuki Asanuma

    International Symposium on Photochemistry (27th PhotoIUPAC) 

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    Event date: 2018.7

    Language:English   Presentation type:Oral presentation (general)  

    Country:Ireland  

  34. 蛍光性核酸塩基導入による新規人工核酸プローブの開発

    村山恵司, 浅沼浩之

    日本化学会第98春季年会 

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    Event date: 2018.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  35. Acyclic artificial nucleic acid circuit for sensitive detection of RNA

    Keiji Murayama, Ryuya Nagao, Hiroyuki Asanuma

    The Second International Symposium on Biofunctional Chemistry (ISBC2017) 

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    Event date: 2017.12

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  36. 非環状型人工核酸で構成されるシグナル増幅回路の開発とRNA可視化への応用

    村山恵司, 長尾竜弥, 浅沼浩之

    第66回高分子討論会 

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    Event date: 2017.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  37. 非環状型人工核酸への色素導入による高機能化

    村山恵司, 樫田啓, 浅沼浩之

    第11回バイオ関連化学シンポジウム 

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    Event date: 2017.9

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  38. 色素導入による非環状型人工核酸の高機能化

    村山恵司, 樫田啓, 浅沼浩之

    2017年光化学討論会 

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    Event date: 2017.9

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  39. 非環状型人工核酸aTNA 及びSNA を利用したシグナル増幅回路の開発

    村山恵司, 長尾竜弥, 浅沼浩之

    第27回バイオ・高分子シンポジウム 

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    Event date: 2017.7

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  40. 天然核酸と直交性を有する人工核酸D-aTNAを用いたHCR回路の開発

    村山恵司, 長尾竜弥, 浅沼浩之

    新学術領域「分子ロボティクス」最終公開シンポジウム「分子ロボティクスの拓く未来」 

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    Event date: 2017.7

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  41. Effect of the chirality of acyclic nucleic acid on its binding affinity for natural nucleic acids

    Keiji Murayama, Hiromu Kashida, Hiroyuki Asanuma

    Nagoya Univ.-Tsinghua Univ.-Toyota Motor Corp.-Hokkaido Univ. Joint Symposium 

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    Event date: 2017.7

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  42. Development of signal amplification circuit composed of acyclic artificial nucleic acids for detection of natural nucleic acids

    Keiji Murayama, Ryuya Nagao, Hiroyuki Asanuma

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    Event date: 2017.5

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  43. 非環状型人工核酸を用いたシグナル増幅回路の開発とRNA検出への応用

    村山恵司, 長尾竜弥, 浅沼浩之

    日本化学会第97春季年会 

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    Event date: 2017.3

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  44. 非環状型人工核酸SNA、iL-aTNAの医療応用に向けた展開

    村山恵司、神元寛、神谷由紀子、樫田啓、浅沼浩之

    名古屋大学 予防早期医療創成センター 第6回ワークショップ 

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    Event date: 2017.1

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  45. Development of Acyclic Artificial Nucleic Acids for Biological Tools

    Keiji Murayama, Yukiko Kamiya, Hiromu Kashida, Hiroyuki Asanuma

    The 5th International Symposium on Dynamical Ordering of Biomolecular Systems for Creation of Integrated Functions 

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    Event date: 2017.1

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  46. L-aTNA as a novel acyclic nucleic acid for the recognition of natural nucleic acids International conference

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    Event date: 2016.10

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  47. Development of super-sensitive fluorescent probe composed of SNA for monitoring of RNA in living cell International conference

    Keiji Murayama, Yukiko Kamiya, Hiromu Kashida, Hiroyuki Asanuma

    The 43rd International Symposium on Nucleic Acid Chemistry 

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    Event date: 2016.9

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  48. DNAへの色素導入リンカーにおけるSerinol骨格へのメチル基導入とキラリティの効果

    村山恵司, 樫田 啓, 浅沼浩之

    第65回高分子討論会 

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    Event date: 2016.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  49. 非環状型人工核酸の主鎖骨格におけるメチル基の位置と立体配座の重要性

    村山恵司, 樫田 啓, 浅沼浩之

    第10回バイオ関連化学シンポジウム 

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    Event date: 2016.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  50. 天然核酸に対する結合制御を目指した非環状型人工核酸の設計とその応用

    村山恵司, 長尾竜弥, 神谷由紀子, 樫田 啓, 浅沼浩之

    第26回バイオ・高分子シンポジウム 

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    Event date: 2016.7

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  51. 非環状型人工核酸の設計における、主鎖骨格上のメチル基の位置とキラリティの重要性

    村山 恵司, 樫田 啓, 浅沼 浩之

    第65回高分子学会年次大会 

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    Event date: 2016.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  52. Importance of chirality and position of methyl group on serinol scaffold for design of acyclic artificial nucleic acid

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    Event date: 2016.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  53. Design of an ultra-sensitive fluorescent probe composed of artificial nucleic acid for visualization of RNA in living cell International conference

    K. Murayama, Y. Kamiya, H. Kashida, H. Asanuma

    Pacifichem2015 

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    Event date: 2015.12

    Language:English   Presentation type:Oral presentation (general)  

    Country:United States  

  54. Design of novel acyclic artificial nucleic acid for improvement of affinity for natural nucleic acids International conference

    K. Murayama, Y. Kamiya, H. Kashida, and H. Asanuma

    International Symposium on EcoTopia Science (ISETS'15)  

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    Event date: 2015.11

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  55. L-aTNA as a new acyclic nucleic acid for the recognition of DNA and RNA International conference

    Keiji Murayama, Hiromu Kashida, Hiroyuki Asanuma

    The 42nd International Symposium on Nucleic Acid Chemistry (ISNAC2015) 

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    Event date: 2015.9

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  56. 天然核酸と安定な二重鎖を形成する新たな非環状型人工核酸の開発

    村山恵司、樫田 啓、浅沼浩之

    第9回バイオ関連化学シンポジウム  

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    Event date: 2015.9

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  57. DNA及びRNAと安定な二重鎖を形成する新規非環状型人工核酸の開発

    村山恵司、樫田 啓、浅沼浩之

    第25回バイオ・高分子シンポジウム 

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    Event date: 2015.7

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  58. DNA及びRNAとの安定な二重鎖形成を目指した新規非環状型人工核酸の設計

    村山恵司, 樫田 啓, 浅沼浩之

    第64回高分子学会年次大会 

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    Event date: 2015.5

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  59. 天然核酸と安定な二重鎖を形成する新規非環状型人工核酸の設計

    村山恵司, 樫田 啓, 浅沼浩之

    日本化学会第95春季年会 

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    Event date: 2015.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  60. Development of an ultra-sensitive fluorescent probe composed of artificial nucleic acid for the detection of mRNA in cell International conference

    Keiji Murayama,; Yukiko Kamiya,; Hiromu Kashida,; Hiroyuki Asanuma

    SCNAC2014 (ⅩⅥth Symposium on Chemistry of Nucleic Acid Components) 

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    Event date: 2014.6

    Language:English   Presentation type:Oral presentation (general)  

    Country:Czech Republic  

  61. Development of an ultra-sensitive fluorescent probe composed of artificial nucleic acid International conference

    Keiji Murayama,; Yoshihiro Tanaka,; Hiromu Kashida,; Hiroyuki Asanuma

    The 40th International Symposium on Nucleic Acid Chemistry 

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    Event date: 2013.11

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  62. Functionalization of novel artificial nucleic acids from acyclic diols by the conjugation with dyes International conference

    Keiji Murayama,; Yoshihiro Tanaka,; Hiromu Kashida,; Hiroyuki Asanuma

    The Second Asian Chemical Biology Conference ACBC2012 

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    Event date: 2012.7

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  63. Control of the helicity of Serinol Nucleic Acid (SNA) by sequence design International conference

    Keiji Murayama,; Hiromu Kashida,; Hiroyuki Asanuma

    Chirality2012 

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    Event date: 2012.6

    Language:English   Presentation type:Poster presentation  

    Country:United States  

  64. New artificial nucleic acids from acyclic diols International conference

    Keiji Murayama,; Takasuke Toda,; Hiromu Kashida,; Hiroyuki Asanuma

    The 38th International Symposium on Nucleic Acid Chemistry (ISNAC2011) 

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    Event date: 2011.11

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  65. 人工生命システム構築に向けた人工核酸XNAの鎖伸長反応 Invited

    村山恵司

    細胞を創る研究会  2023.9.25 

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    Presentation type:Oral presentation (invited, special)  

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  66. 人工生命システム創製を目指した人工核酸XNAの鎖伸長反応の開発 Invited

    村山恵司

    第54回中部化学関係学協会支部連合秋季大会  2023.11.11 

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    Presentation type:Oral presentation (invited, special)  

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Research Project for Joint Research, Competitive Funding, etc. 2

  1. 人工核酸L-aTNAの非酵素的鎖伸長反応を利用した配列転写・逆転写法の開発

    2022.4 - 2023.3

    第34回 研究助成(研究育成型) 

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    Authorship:Principal investigator 

  2. 人工核酸L-ATNAの配列複製・転写反応を目指したケミカルライゲーション法の開発

    2020.6 - 2021.3

    2020年度 研究助成 

    村山恵司

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\1500000

KAKENHI (Grants-in-Aid for Scientific Research) 6

  1. Development of reaction-diffusion based neural network systems

    Grant number:23H00506  2023.4 - 2027.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (A)

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    Authorship:Coinvestigator(s) 

  2. Management / Public Relations / International Activity Support of Molecular Cybernetics

    Grant number:20H05968  2020.11 - 2025.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Transformative Research Areas (A)

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    Authorship:Coinvestigator(s) 

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  3. Development of Molecular Information Transmitting Devices for Minimal Artificial Brain

    Grant number:20H05970  2020.11 - 2025.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Transformative Research Areas (A)

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    Authorship:Coinvestigator(s) 

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  4. Photo-ligation of SNA via photo-responsive nucleobases

    Grant number:20K15399  2020.4 - 2022.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Early-Career Scientists

    Murayama Keiji

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    Authorship:Principal investigator 

    Grant amount:\4160000 ( Direct Cost: \3200000 、 Indirect Cost:\960000 )

    Ligation of nucleic acids generates complementary strand for template from fragment strands via formation of phosphodiester bond, which is significantly important for various biological technology including genetic recombination, nucleic acid architecture, and nucleic acid detection. In this project, we have newly developed photo-ligation of SNA, artificial nucleic acid, on a template RNA strand. SNA fragments carrying photo-responsive nucleobase can be effectively ligated on RNA template by the irradiation of 365 nm light.

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  5. Design of L-DNA/SNA circuit for detection of RNA in cell with high sensitivity and accuracy

    Grant number:17K14514  2017.4 - 2020.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Young Scientists (B)

    Murayama Keiji

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    Authorship:Principal investigator 

    Grant amount:\4420000 ( Direct Cost: \3400000 、 Indirect Cost:\1020000 )

    We attempted to develop the RNA detection system achieved by transfer of RNA information into L-DNA, mirror of natural DNA, and amplified the fluorescent signal. As a result, we successfully establish RNA detection without inhibition by contaminating and nucleases. We also found that L-DNA-bound SNA induced left-handed helicity that significantly reduced hybridization of SNA with right-handed natural nucleic acids.

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  6. 人工核酸の自己複製・翻訳反応の開発と分子進化法への応用

    Grant number:JPMJFR2226 

    創発的研究支援事業 

    村山恵司

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    Authorship:Principal investigator 

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Industrial property rights 2

  1. ポリヌクレオチドの連結方法

    浅沼浩之, 村山恵司, 栗木琢実

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    Applicant:国立大学法人名古屋大学

    Application no:10722017JP  Date applied:2018.2

    Country of applicant:Domestic  

  2. オリゴヌクレオチド

    浅沼浩之, 樫田 啓, 村山恵司

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    Application no:特願2015-149522  Date applied:2015.7

    Announcement no:特開2016-130232  Date announced:2016.7

    Country of applicant:Domestic  

 

Teaching Experience (On-campus) 10

  1. 生命分子工学実験3

    2020

  2. 生命分子工学実験1

    2020

  3. 生命分子工学実験1

    2019

  4. 生命分子工学実験3

    2019

  5. 分析化学実験第1

    2018

  6. 生物機能工学実験

    2018

  7. 分析化学実験第1

    2017

  8. 生物機能工学実験

    2017

  9. 分析化学実験第1

    2016

  10. 生物機能工学実験

    2016

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Teaching Experience (Off-campus) 10

  1. 生体物質合成化学

    2020.4 - 2021.3 Aichi Institute of Technology)

  2. 生体物質合成化学

    2019.4 - 2020.3 Aichi Institute of Technology)

  3. 生命分子工学実験1

    2019 Nagoya University)

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  4. 生命分子工学実験3

    2019 Nagoya University)

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  5. 生体物質合成化学

    2018.4 - 2019.3 Aichi Institute of Technology)

  6. 生体物質合成化学

    2017.4 - 2018.3 Aichi Institute of Technology)

  7. 生体物質合成化学

    2016.4 - 2022.8 Aichi Institute of Technology)

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  8. 生体物質合成化学

    2016.4 - 2017.3 Aichi Institute of Technology)

  9. 生物機能工学実験

    2016 - 2018 Nagoya University)

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  10. 分析化学実験第1

    2016 - 2018 Nagoya University)

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