研究者詳細 - 菅波　孝祥

論文 - 菅波　孝祥

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Novel Cell-to-Cell Communications Between Macrophages and Fibroblasts Regulate Obesity-Induced Adipose Tissue Fibrosis 招待有り査読有り Open Access

Kohda, H; Tanaka, M; Shichino, S; Arakawa, S; Komori, T; Ito, A; Wada, E; Ochi, K; Yuan, XM; Takeda, T; Saiki, A; Tatsuno, I; Ikeda, K; Miyai, Y; Enomoto, A; Morikawa, Y; Shimizu, S; Ueha, S; Matsushima, K; Ogawa, Y; Suganami, T

DIABETES 74 巻 ( 7 ) 頁： 1135 - 1152 2025年7月

Lipid metabolism in myeloid cell function and chronic inflammatory diseases

Ito, A; Suganami, T

FRONTIERS IN IMMUNOLOGY 15 巻頁： 1495853 2025年1月

Genome-wide CRISPR-Cas9 screen for the identification of genes modulating lenvatinib resistance in HCC

Zhou, S; Abe, Y; Kajino, T; Isomura, H; Tanaka, M; Yamaguchi, R; Suganami, T; Taguchi, A

CANCER SCIENCE 116 巻頁： 1363 - 1363 2025年1月

Meflin/ISLR is a marker of adipose stem and progenitor cells in mice and humans that suppresses white adipose tissue remodeling and fibrosis

Ishihara, T; Kato, K; Matsumoto, K; Tanaka, M; Hara, A; Shiraki, Y; Morisaki, H; Urano, Y; Ando, R; Ito, K; Mii, S; Esaki, N; Furuhashi, K; Takefuji, M; Suganami, T; Murohara, T; Enomoto, A

GENES TO CELLS 29 巻 ( 10 ) 頁： 902 - 920 2024年10月

Oya, M; Miyasaka, Y; Nakamura, Y; Tanaka, M; Suganami, T; Mashimo, T; Nakamura, K

CELL METABOLISM 36 巻 ( 5 ) 頁： 1044 - 1058.e10 2024年5月

Imeglimin Exhibits Novel Anti-Inflammatory Effects on High-Glucose-Stimulated Mouse Microglia through ULK1-Mediated Suppression of the TXNIP-NLRP3 Axis

Kato, H; Iwashita, K; Iwasa, M; Kato, S; Yamakage, H; Suganami, T; Tanaka, M; Satoh-Asahara, N

CELLS 13 巻 ( 3 ) 2024年2月

Lysosomal cholesterol overload in macrophages promotes liver fibrosis in a mouse model of NASH

Itoh, M; Tamura, A; Kanai, S; Tanaka, M; Kanamori, Y; Shirakawa, I; Ito, A; Oka, Y; Hidaka, I; Takami, T; Honda, Y; Maeda, M; Saito, Y; Murata, Y; Matozaki, T; Nakajima, A; Kataoka, Y; Ogi, T; Ogawa, Y; Suganami, T

JOURNAL OF EXPERIMENTAL MEDICINE 220 巻 ( 11 ) 2023年9月

The new findings of disordered BCAA catabolism for metabolic disease

Wada, E; Suganami, T; Kitamura, T

ANNALS OF NUTRITION AND METABOLISM 79 巻頁： 244 - 244 2023年8月

Taxifolin Suppresses Inflammatory Responses of High-Glucose-Stimulated Mouse Microglia by Attenuating the TXNIP-NLRP3 Axis

Iwasa, M; Kato, H; Iwashita, K; Yamakage, H; Kato, S; Saito, S; Ihara, M; Nishimura, H; Kawamoto, A; Suganami, T; Tanaka, M; Satoh-Asahara, N

NUTRIENTS 15 巻 ( 12 ) 2023年6月

Tissue transglutaminase exacerbates renal fibrosis via alternative activation of monocyte-derived macrophages

Shinoda, Y; Tatsukawa, H; Yonaga, A; Wakita, R; Takeuchi, T; Tsuji, T; Tanaka, M; Suganami, T; Hitomi, K

CELL DEATH & DISEASE 14 巻 ( 2 ) 頁： 136 2023年3月

Medium-chain fatty acids suppress lipotoxicity-induced hepatic fibrosis via the immunomodulating receptor GPR84

Ohue-Kitano, R; Nonaka, H; Nishida, A; Masujima, Y; Takahashi, D; Ikeda, T; Uwamizu, A; Tanaka, M; Kohjima, M; Igarashi, M; Katoh, H; Tanaka, T; Inoue, A; Suganami, T; Hase, K; Ogawa, Y; Aoki, J; Kimura, I

JCI INSIGHT 8 巻 ( 2 ) 2023年1月

Novel Therapeutic Potentials of Taxifolin for Obesity-Induced Hepatic Steatosis, Fibrogenesis, and Tumorigenesis

Inoue, T; Fu, B; Nishio, M; Tanaka, M; Kato, H; Tanaka, M; Itoh, M; Yamakage, H; Ochi, K; Ito, A; Shiraki, Y; Saito, S; Ihara, M; Nishimura, H; Kawamoto, A; Inoue, S; Saeki, K; Enomoto, A; Suganami, T; Satoh-Asahara, N

NUTRIENTS 15 巻 ( 2 ) 2023年1月

Molecular mechanism of crosstalk between immune and metabolic systems in metabolic syndrome

Hachiya, R; Tanaka, M; Itoh, M; Suganami, T

INFLAMMATION AND REGENERATION 42 巻 ( 1 ) 頁： 13 2022年5月

FOXO1 cooperates with C/EBPδ and ATF4 to regulate skeletal muscle atrophy transcriptional program during fasting

Oyabu, M; Takigawa, K; Mizutani, S; Hatazawa, Y; Fujita, M; Ohira, Y; Sugimoto, T; Suzuki, O; Tsuchiya, K; Suganami, T; Ogawa, Y; Ishihara, K; Miura, S; Kamei, Y

FASEB JOURNAL 36 巻 ( 2 ) 頁： e22152 2022年2月

A Porous Reservoir-Backed Boronate Gel Microneedle for Efficient Skin Penetration and Sustained Glucose-Responsive Insulin Delivery

Chen, SY; Miyazaki, T; Itoh, M; Matsumoto, H; Moro-Oka, Y; Tanaka, M; Miyahara, Y; Suganami, T; Matsumoto, A

GELS 8 巻 ( 2 ) 2022年2月

Boronic Acid Ligands Can Target Multiple Subpopulations of Pancreatic Cancer Stem Cells via pH-Dependent Glycan-Terminal Sialic Acid Recognition

Miyazaki, T; Khan, T; Tachihara, Y; Itoh, M; Miyazawa, T; Suganami, T; Miyahara, Y; Cabral, H; Matsumoto, A

ACS APPLIED BIO MATERIALS 4 巻 ( 9 ) 頁： 6647 - 6651 2021年9月

The sodium-glucose cotransporter-2 inhibitor Tofogliflozin prevents the progression of nonalcoholic steatohepatitis-associated liver tumors in a novel murine model

Yoshioka, N; Tanaka, M; Ochi, K; Watanabe, A; Ono, K; Sawada, M; Ogi, T; Itoh, M; Ito, A; Shiraki, Y; Enomoto, A; Ishigami, M; Fujishiro, M; Ogawa, Y; Suganami, T

BIOMEDICINE & PHARMACOTHERAPY 140 巻頁： 111738 2021年8月

Role of chronic inflammation in the pathogenesis of nonalcoholic steatohepatitis: lessons from a unique mouse model using melanocortin receptor-deficient mice.

Itoh M, Suganami T, Ogawa Y

Endocrine journal 68 巻 ( 7 ) 頁： 743 - 749 2021年7月

Obesity accelerates hair thinning by stem cell-centric converging mechanisms

Morinaga, H; Mohri, Y; Grachtchouk, M; Asakawa, K; Matsumura, H; Oshima, M; Takayama, N; Kato, T; Nishimori, Y; Sorimachi, Y; Takubo, K; Suganami, T; Iwama, A; Iwakura, Y; Dlugosz, AA; Nishimura, EK

NATURE 595 巻 ( 7866 ) 頁： 266 - + 2021年7月

Dietary Supplementation With Eicosapentaenoic Acid Inhibits Plasma Cell Differentiation and Attenuates Lupus Autoimmunity

Kobayashi, A; Ito, A; Shirakawa, I; Tamura, A; Tomono, S; Shindou, H; Hedde, PN; Tanaka, M; Tsuboi, N; Ishimoto, T; Akashi-Takamura, S; Maruyama, S; Suganami, T

FRONTIERS IN IMMUNOLOGY 12 巻頁： 650856 2021年6月

Macrophages rely on extracellular serine to suppress aberrant cytokine production

Kurita, K; Ohta, H; Shirakawa, I; Tanaka, M; Kitaura, Y; Iwasaki, Y; Matsuzaka, T; Shimano, H; Aoe, S; Arima, H; Ogawa, Y; Ito, A; Suganami, T

SCIENTIFIC REPORTS 11 巻 ( 1 ) 頁： 11137 2021年5月

Iron-rich Kupffer cells exhibit phenotypic changes during the development of liver fibrosis in NASH

Kanamori, Y; Tanaka, M; Itoh, M; Ochi, K; Ito, A; Hidaka, I; Sakaida, I; Ogawa, Y; Suganami, T

ISCIENCE 24 巻 ( 2 ) 頁： 102032 2021年2月

Role of chronic inflammation in the pathogenesis of nonalcoholic steatohepatitis: lessons from a unique mouse model using melanocortin receptor-deficient mice

Itoh Michiko, Suganami Takayoshi, Ogawa Yoshihiro

ENDOCRINE JOURNAL 68 巻 ( 7 ) 頁： 743 - 749 2021年

Digenic mutations in ALDH2 and ADH5 impair formaldehyde clearance and cause a multisystem disorder, AMeD syndrome

Oka, Y; Hamada, M; Nakazawa, Y; Muramatsu, H; Okuno, Y; Higasa, K; Shimada, M; Takeshima, H; Hanada, K; Hirano, T; Kawakita, T; Sakaguchi, H; Ichimura, T; Ozono, S; Yuge, K; Watanabe, Y; Kotani, Y; Yamane, M; Kasugai, Y; Tanaka, M; Suganami, T; Nakada, S; Mitsutake, N; Hara, Y; Kato, K; Mizuno, S; Miyake, N; Kawai, Y; Tokunaga, K; Nagasaki, M; Kito, S; Isoyama, K; Onodera, M; Kaneko, H; Matsumoto, N; Matsuda, F; Matsuo, K; Takahashi, Y; Mashimo, T; Kojima, S; Ogi, T

SCIENCE ADVANCES 6 巻 ( 51 ) 2020年12月

C-type lectin Mincle mediates cell death-triggered inflammation in acute kidney injury

Tanaka, M; Saka-Tanaka, M; Ochi, K; Fujieda, K; Sugiura, Y; Miyamoto, T; Kohda, H; Ito, A; Miyazawa, T; Matsumoto, A; Aoe, S; Miyamoto, Y; Tsuboi, N; Maruyama, S; Suematsu, M; Yamasaki, S; Ogawa, Y; Suganami, T

JOURNAL OF EXPERIMENTAL MEDICINE 217 巻 ( 11 ) 2020年11月

Blocking sphingosine 1-phosphate receptor 2 accelerates hepatocellular carcinoma progression in a mouse model of NASH

Yoshida, T; Tsuchiya, A; Kumagai, M; Takeuchi, S; Nojiri, S; Watanabe, T; Ogawa, M; Itoh, M; Takamura, M; Suganami, T; Ogawa, Y; Terai, S

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 530 巻 ( 4 ) 頁： 665 - 672 2020年10月

Gut Hormone GIP Induces Inflammation and Insulin Resistance in the Hypothalamus

Fu, Y; Kaneko, K; Lin, HY; Mo, QX; Xu, Y; Suganami, T; Ravn, P; Fukuda, M

ENDOCRINOLOGY 161 巻 ( 9 ) 2020年9月

Chronic inflammation as a molecular basis of nonalcoholic steatohepatitis: role of macrophages and fibroblasts in the liver

Itoh, M; Ogawa, Y; Suganami, T

NAGOYA JOURNAL OF MEDICAL SCIENCE 82 巻 ( 3 ) 頁： 391 - 397 2020年8月

Temperature-Stable Boronate Gel-Based Microneedle Technology for Self-Regulated Insulin Delivery

Chen, SY; Miyazaki, T; Itoh, M; Matsumoto, H; Moro-oka, Y; Tanaka, M; Miyahara, Y; Suganami, T; Matsumoto, A

ACS APPLIED POLYMER MATERIALS 2 巻 ( 7 ) 頁： 2781 - 2790 2020年7月

Hollow fiber-combined glucose-responsive gel technology as an in vivo electronics-free insulin delivery system

Matsumoto, A; Kuwata, H; Kimura, S; Matsumoto, H; Ochi, K; Moro-oka, Y; Watanabe, A; Yamada, H; Ishii, H; Miyazawa, T; Chen, SY; Baba, T; Yoshida, H; Nakamura, T; Inoue, H; Ogawa, Y; Tanaka, M; Miyahara, Y; Suganami, T

COMMUNICATIONS BIOLOGY 3 巻 ( 1 ) 頁： 313 2020年6月

Development of a non-alcoholic steatohepatitis model with rapid accumulation of fibrosis, and its treatment using mesenchymal stem cells and their small extracellular vesicles

Watanabe Takayuki, Tsuchiya Atsunori, Takeuchi Suguru, Nojiri Shunsuke, Yoshida Tomoaki, Ogawa Masahiro, Itoh Michiko, Takamura Masaaki, Suganami Takayoshi, Ogawa Yoshihiro, Terai Shuji

REGENERATIVE THERAPY 14 巻頁： 252 - 261 2020年6月

Development of a non-alcoholic steatohepatitis model with rapid accumulation of fibrosis, and its treatment using mesenchymal stem cells and their small extracellular vesicles.

Watanabe T, Tsuchiya A, Takeuchi S, Nojiri S, Yoshida T, Ogawa M, Itoh M, Takamura M, Suganami T, Ogawa Y, Terai S

Regenerative therapy 14 巻頁： 252 - 261 2020年6月

Ubiquitination of DNA Damage-Stalled RNAPII Promotes Transcription-Coupled Repair

Nakazawa, Y; Hara, Y; Oka, Y; Komine, O; van den Heuvel, D; Guo, CW; Daigaku, Y; Isono, M; He, YX; Shimada, M; Kato, K; Jia, N; Hashimoto, S; Kotani, Y; Miyoshi, Y; Tanaka, M; Sobue, A; Mitsutake, N; Suganami, T; Masuda, A; Ohno, K; Nakada, S; Mashimo, T; Yamanaka, K; Luijsterburg, MS; Ogi, T

CELL 180 巻 ( 6 ) 頁： 1228 - + 2020年3月

Dipeptidyl peptidase-4 inhibition prevents nonalcoholic steatohepatitis-associated liver fibrosis and tumor development in mice independently of its anti-diabetic effects

Kawakubo, M; Tanaka, M; Ochi, K; Watanabe, A; Saka-Tanaka, M; Kanamori, Y; Yoshioka, N; Yamashita, S; Goto, M; Itoh, M; Shirakawa, I; Kanai, S; Suzuki, H; Sawada, M; Ito, A; Ishigami, M; Fujishiro, M; Arima, H; Ogawa, Y; Suganami, T

SCIENTIFIC REPORTS 10 巻 ( 1 ) 頁： 983 2020年1月

Upregulation of cancer-associated gene expression in activated fibroblasts in a mouse model of non-alcoholic steatohepatitis

Asakawa, M; Itoh, M; Suganami, T; Sakai, T; Kanai, S; Shirakawa, I; Yuan, XM; Hatayama, T; Shimada, S; Akiyama, Y; Fujiu, K; Inagaki, Y; Manabe, I; Yamaoka, S; Yamada, T; Tanaka, S; Ogawa, Y

SCIENTIFIC REPORTS 9 巻 ( 1 ) 頁： 19601 2019年12月

Smart Microneedle Fabricated with Silk Fibroin Combined Semi interpenetrating Network Hydrogel for Glucose-Responsive Insulin Delivery

Chen, SY; Matsumoto, H; Moro-oka, Y; Tanaka, M; Miyahara, Y; Suganami, T; Matsumoto, A

ACS BIOMATERIALS SCIENCE & ENGINEERING 5 巻 ( 11 ) 頁： 5781 - 5789 2019年11月

Evaluation of hepatic function using dynamic contrast-enhanced magnetic resonance imaging in melanocortin 4 receptor-deficient mice as a model of nonalcoholic steatohepatitis

Yamada, T; Kashiwagi, Y; Rokugawa, T; Kato, H; Konishi, H; Hamada, T; Nagai, R; Masago, Y; Itoh, M; Suganami, T; Ogawa, Y; Abe, K

MAGNETIC RESONANCE IMAGING 57 巻頁： 210 - 217 2019年4月

Microneedle-Array Patch Fabricated with Enzyme-Free Polymeric Components Capable of On-Demand Insulin Delivery

Chen, SY; Matsumoto, H; Moro-oka, Y; Tanaka, M; Miyahara, Y; Suganami, T; Matsumoto, A

ADVANCED FUNCTIONAL MATERIALS 29 巻 ( 7 ) 2019年2月

Obeticholic acid protects against hepatocyte death and liver fibrosis in a murine model of nonalcoholic steatohepatitis

Goto, T; Itoh, M; Suganami, T; Kanai, S; Shirakawa, I; Sakai, T; Asakawa, M; Yoneyama, T; Kai, T; Ogawa, Y

SCIENTIFIC REPORTS 8 巻 ( 1 ) 頁： 8157 2018年5月

Fatty Acid Binding Protein 4 (FABP4) Overexpression in Intratumoral Hepatic Stellate Cells within Hepatocellular Carcinoma with Metabolic Risk Factors

Chiyonobu, N; Shimada, S; Akiyama, Y; Mogushi, K; Itoh, M; Akahoshi, K; Matsumura, S; Ogawa, K; Ono, H; Mitsunori, Y; Ban, D; Kudo, A; Arii, S; Suganami, T; Yamaoka, S; Ogawa, Y; Tanabe, M; Tanaka, S

AMERICAN JOURNAL OF PATHOLOGY 188 巻 ( 5 ) 頁： 1213 - 1224 2018年5月

Molecular mechanism of obesity-induced "metabolic' tissue remodeling

Tanaka, M; Itoh, M; Ogawa, Y; Suganami, T

JOURNAL OF DIABETES INVESTIGATION 9 巻 ( 2 ) 頁： 256 - 261 2018年3月

Canagliflozin, an SGLT2 inhibitor, attenuates the development of hepatocellular carcinoma in a mouse model of human NASH

Shiba, K; Tsuchiya, K; Komiya, C; Miyachi, Y; Mori, K; Shimazu, N; Yamaguchi, S; Ogasawara, N; Katoh, M; Itoh, M; Suganami, T; Ogawa, Y

SCIENTIFIC REPORTS 8 巻 ( 1 ) 頁： 2362 2018年2月

CD11c+ resident macrophages drive hepatocyte death-triggered liver fibrosis in a murine model of nonalcoholic steatohepatitis

Itoh, M; Suganami, T; Kato, H; Kanai, S; Shirakawa, I; Sakai, T; Goto, T; Asakawa, M; Hidaka, I; Sakugawa, H; Ohnishi, K; Komohara, Y; Asano, K; Sakaida, I; Tanaka, M; Ogawa, Y

JCI INSIGHT 2 巻 ( 22 ) 2017年11月

Synthetic "smart gel" provides glucose-responsive insulin delivery in diabetic mice

Matsumoto, A; Tanaka, M; Matsumoto, H; Ochi, K; Moro-oka, Y; Kuwata, H; Yamada, H; Shirakawa, I; Miyazawa, T; Ishii, H; Kataoka, K; Ogawa, Y; Miyahara, Y; Suganami, T

SCIENCE ADVANCES 3 巻 ( 11 ) 頁： eaaq0723 2017年11月

Sphingosine 1-Phosphate (S1P) and its receptor S1PR2 regulate ductular reaction in a mouse model of nonalcoholic steatohepatitis

Kato, H; Itoh, M; Suganami, T; Nagai, R; Ishimoto, Y; Hashimoto, K; Morita, A; Yogo, E; Rokushima, M; Ogawa, Y

HEPATOLOGY 66 巻頁： 1046A - 1047A 2017年10月

Hepatocyte death-triggered CD11c-positive macrophage accumulation induces liver fibrosis in a murine model of non-alcoholic steatohepatitis

Itoh, M; Suganami, T; Kanai, S; Shirakawa, I; Sakai, T; Goto, T; Asakawa, M; Hidaka, I; Sakaida, I; Ogawa, Y

HEPATOLOGY 66 巻頁： 1052A - 1052A 2017年10月

The short chain fatty acid receptor GPR43 regulates inflammatory signals in adipose tissue M2-type macrophages

Nakajima, A; Nakatani, A; Hasegawa, S; Irie, J; Ozawa, K; Tsujimoto, G; Suganami, T; Itoh, H; Kimura, I

PLOS ONE 12 巻 ( 7 ) 頁： e0179696 2017年7月

WNK4 is an Adipogenic Factor and Its Deletion Reduces Diet-Induced Obesity in Mice

Takahashi, D; Mori, T; Sohara, E; Tanaka, M; Chiga, M; Inoue, Y; Nomura, N; Zeniya, M; Ochi, H; Takeda, S; Suganami, T; Rai, T; Uchida, S

EBIOMEDICINE 18 巻頁： 118 - 127 2017年4月

Antifibrotic effect of pirfenidone in a mouse model of human nonalcoholic steatohepatitis

Komiya, C; Tanaka, M; Tsuchiya, K; Shimazu, N; Mori, K; Furuke, S; Miyachi, Y; Shiba, K; Yamaguchi, S; Ikeda, K; Ochi, K; Nakabayashi, K; Hata, K; Itoh, M; Suganami, T; Ogawa, Y

SCIENTIFIC REPORTS 7 巻頁： 44754 2017年3月

Inflammatory responses increase secretion of MD-1 protein.

Thomas Jennings R, Odkhuu E, Nakashima A, Morita N, Kobayashi T, Yamai I, Tanaka M, Suganami T, Haga S, Ozaki M, Watanabe Y, Nagai Y, Takatsu K, Kikuchi-Ueda T, Ichimonji I, Ogawa Y, Takagi H, Yamazaki T, Miyake K, Akashi-Takamura S

International immunology 28 巻 ( 10 ) 頁： 503-512 2016年10月

The H3K9 methyltransferase Setdb1 regulates TLR4-mediated inflammatory responses in macrophages.

Hachiya R, Shiihashi T, Shirakawa I, Iwasaki Y, Matsumura Y, Oishi Y, Nakayama Y, Miyamoto Y, Manabe I, Ochi K, Tanaka M, Goda N, Sakai J, Suganami T, Ogawa Y

Scientific reports 6 巻頁： 28845 2016年6月

Isoliquiritigenin Attenuates Adipose Tissue Inflammation in vitro and Adipose Tissue Fibrosis through Inhibition of Innate Immune Responses in Mice.

Watanabe Y, Nagai Y, Honda H, Okamoto N, Yamamoto S, Hamashima T, Ishii Y, Tanaka M, Suganami T, Sasahara M, Miyake K, Takatsu K

Scientific reports 6 巻頁： 23097 2016年3月

Undernourishment in utero Primes Hepatic Steatosis in Adult Mice Offspring on an Obesogenic Diet; Involvement of Endoplasmic Reticulum Stress.

Muramatsu-Kato K, Itoh H, Kohmura-Kobayashi Y, Ferdous UJ, Tamura N, Yaguchi C, Uchida T, Suzuki K, Hashimoto K, Suganami T, Ogawa Y, Kanayama N

Scientific reports 5 巻頁： 16867 2015年11月

Integration of transcriptome and methylome analysis of aldosterone-producing adenomas.

Murakami M, Yoshimoto T, Nakabayashi K, Tsuchiya K, Minami I, Bouchi R, Izumiyama H, Fujii Y, Abe K, Tayama C, Hashimoto K, Suganami T, Hata K, Kihara K, Ogawa Y

European journal of endocrinology 173 巻 ( 2 ) 頁： 185-95 2015年8月

Eicosapentaenoic acid ameliorates non-alcoholic steatohepatitis in a novel mouse model using melanocortin 4 receptor-deficient mice.

Konuma K, Itoh M, Suganami T, Kanai S, Nakagawa N, Sakai T, Kawano H, Hara M, Kojima S, Izumi Y, Ogawa Y

PloS one 10 巻 ( 3 ) 頁： e0121528 2015年3月

Parenchymal-stromal cell interaction in metabolic diseases. 査読有り

Y. Ogawa, T. Suganami, M. Tanaka, M. Itoh.

Inflamm. Regen. 35 巻頁： 167-171 2015年

Ligand-activated PPARα-dependent DNA demethylation regulates the fatty acid β-oxidation genes in the postnatal liver.

T. Ehara, Y. Kamei, X. Yuan, M. Takahashi, S. Kanai, K. Tsujimoto, T. Tamiya, Y. Nakagawa, H. Shimano, T. Takai-Igarashi, I. Hatada, T. Suganami, K. Hashimoto, Y. Ogawa.

Diabetes 64 巻頁： 775-784 2015年

ATM regulates adipocyte differentiation and contributes to glucose homeostasis.

M. Takagi, H. Uno, R. Nishi, M. Sugimoto, S. Hasegwa, J. Piao, N. Ihara, S. Kanai, S. Kakei, Y. Tamura, T. Suganami, Y. Kamei, T. Shimizu, A. Yasuda, Y. Ogawa, S. Mizutani.

Cell Reports 10 巻頁： 957-967 2015年

Favine/CCDC3 is involved in lipid accumulation.

S. Kobayashi, A. Fukuhara, M. Otsuki, T. Suganami, Y. Ogawa, E. Morii, I. Shimomura.

J. Biol. Chem. 290 巻頁： 7443-7451 2015年

Eicosapentaenoic acid ameliorates non-alcoholic steatohepatitis in a novel mouse model using Melanocortin 4 receptor-deficient mice. 査読有り

K. Konuma, M. Itoh, T. Suganami, S. Kanai, N. Nakagawa, T. Sakai, H. Kawano, M. Hara, S. Kojima, Y. Izumi, Y. Ogawa.

PLoS ONE 10 巻頁： e0121528 2015年

Integration of transcriptome and methylome analysis of aldosterone-producing adenomas.

M. Murakami, T. Yoshimoto, K. Nakabayashi, K. Tsuchiya, I. Minami, R. Bouchi, H. Izumiyama, Y. Fujii, K. Abe, C. Tayama, K. Hashimoto, T. Suganami, KI. Hata, K. Kihara, Y. Ogawa.

Eur. J. Endocrinol. 173 巻頁： 185-195 2015年

Macrophage-inducible C-type lectin underlies obesity-induced adipose tissue fibrosis. 査読有り

M. Tanaka, K. Ikeda, T. Suganami, C. Komiya, K. Ochi, I. Shirakawa, M. Hamaguchi, S. Nishimura, I. Manabe, T. Matsuda, K. Kimura, H. Inoue, Y. Inagaki, S. Aoe, S. Yamasaki, Y. Ogawa.

Nat. Commun. 5 巻頁： 4982 2014年

FOXO1 activates glutamine synthetase gene in mouse skeletal muscles through a region downstream of 3'-UTR; possible contribution to ammonia detoxification.

Y. Kamei, M. Hattori, Y. Hatazawa, T. Kasahara, M. Kanou, S. Kanai, X. Yuan, T. Suganami, WH. Lamers, T. Kitamura, Y. Ogawa.

Am. J. Physiol. 307 巻頁： E485-E493 2014年

Increase in EPA/AA ratio associated with improved arterial stiffness in obese patients with dyslipidemia.

R. Ito, N. Satoh-Asahara, H. Yamakage, Y. Sasaki, S., Odori, S. Kono, H. Wada, T. Suganami, Y. Ogawa, K. Hasegawa, A. Shimatsu.

J. Atheroscler. Thromb. 21 巻頁： 248-260 2014年

Possible involvement of Opa-Interacting Protein 5 in adipose proliferation and obesity.

K. Inoue, N. Maeda, T. Mori, R. Sekimoto, Y. Tsushima, K. Matsuda, M. Yamaoka, T. Suganami, H. Nishizawa, Y. Ogawa, T. Funahashi, I. Shimomura.

PLoS ONE 9 巻頁： e87661 2014年

Activating transcription factor 4 links metabolic stress to interleukin-6 expression in macrophages. 査読有り

Y. Iwasaki, T. Suganami, R. Hachiya, I. Shirakawa, M. Kim-Saijo, M. Tanaka, M. Hamaguchi, T. Takai-Igarashi, M. Nakai, Y. Miyamoto, Y. Ogawa.

Diabetes 63 巻頁： 152-161 2014年

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