Organization
Research Institute of Environmental Medicine Designated associate professor
Title
Designated associate professor
MORITA Mikio
Degree 2
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Ph.D. （ 2011.3 Nagoya City University ）
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Master （ 1999.3 Tokyo Institute of Technology ）
Research Interests 3
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computational chemistry
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Medicinal Chemistry
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Organic Synthesis
Research History 3
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Nagoya University Designated associate professor
2019.4
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RaQualia Pharma
2008.7
Country：Japan
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Pfizer
1999.4 - 2008.6
Country：Japan
Papers 7
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Structural Basis for Binding of Potassium-Competitive Acid Blockers to the Gastric Proton Pump Reviewed International coauthorship
Saki Tanaka, Mikio Morita, Tatsuya Yamagishi, Hridya Valia Madapally, Kenichi Hayashida, Himanshu Khandelia, Christoph Gerle, Hideki Shigematsu, Atsunori Oshima, Kazuhiro Abe
Journal of Medicinal Chemistry Vol. 65 ( 11 ) page： 7843 - 7853 2022.5
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Systematic asymmetric analog synthesis of fluspidine, a σ1 receptor ligand, to improve ligand affinity Reviewed
Shinji Tanaka, Sho Yoshinaka, Kiyoshi Kawamura, Mikio Morita, Masato Kitamura
Tetrahedron Letters Vol. 85 page： 153250 2021.7
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Facile synthesis of 1-methyl-1H-benzo[b]azepines from 1-methylquinolinium iodides and diazo(trimethylsilyl)methylmagnesium bromide. Reviewed
Morita, M.; Hari, Y.; Aoyama, T.
Synthesis Vol. 2010 ( 24 ) page： 4221-4227 2010
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Facile synthesis of 2-azaazulenes from thiobenzoyl isocyanates using trimethylsilyldiazomethane. Reviewed
Morita, M.; Hari, Y.; Iguchi, T.; Aoyama, T.
Tetrahedron Vol. 64 ( 8 ) page： 1753-1758 2008
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Unusual double-bond migration as a plausible key reaction in the biosynthesis of the isoprenoidal membrane lipids of methanogenic archaea. Reviewed
Eguchi, T.; Takyo, H.; Morita, M.; Kakinuma, K.; Koga, Y.
Chemical Communications Vol. 2000 ( 16 ) page： 1545-1546 2000
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Structural diversity of the membrane core lipids of extreme halophiles. Reviewed
Morita, M.; Yamauchi, N.; Eguchi, T.; Kakinuma, K.
Bioscience, Biotechnology, and Biochemistry Vol. 62 ( 3 ) page： 596-598 1998
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Multigram synthesis of mevalonolactone-d9 and its application to stereochemical analysis by 1H NMR of the saturation reaction in the biosynthesis of the 2,3-di-O-phytanyl-sn-glycerol core of the archaeal membrane lipid. Reviewed
Eguchi, T.; Morita, M; Kakinuma, K.
Journal of the American Chemical Society Vol. 120 ( 22 ) page： 5427-5433 1998