Updated on 2022/06/01

写真a

 
HAYASHI Masamichi
 
Organization
Nagoya University Hospital Gastroenterological Surgery 2 Lecturer
Title
Lecturer

Degree 1

  1. Doctor(Medical) ( 2012.3   Nagoya University ) 

 

Papers 175

  1. GULP1 regulates the NRF2-KEAP1 signaling axis in urothelial carcinoma.

    Hayashi M, Guida E, Inokawa Y, Goldberg R, Reis LO, Ooki A, Pilli M, Sadhukhan P, Woo J, Choi W, Izumchenko E, Gonzalez LM, Marchionni L, Zhavoronkov A, Brait M, Bivalacqua T, Baras A, Netto GJ, Koch W, Singh A, Hoque MO

    Science signaling   Vol. 13 ( 645 )   2020.8

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    Language:English  

    DOI: 10.1126/scisignal.aba0443

    PubMed

  2. Correlation of gene methylation in surgical margin imprints with locoregional recurrence in head and neck squamous cell carcinoma.

    Hayashi M, Wu G, Roh JL, Chang X, Li X, Ahn J, Goldsmith M, Khan Z, Bishop J, Zhang Z, Zhou XC, Richmon J, Agrawal N, Koch WM

    Cancer   Vol. 121 ( 12 ) page: 1957-65   2015.6

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/cncr.29303

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  3. Impact of molecular surgical margin analysis on the prediction of pancreatic cancer recurrences after pancreaticoduodenectomy

    Sunagawa Yuki, Hayashi Masamichi, Yamada Suguru, Tanabe Hiroshi, Kurimoto Keisuke, Tanaka Nobutake, Sonohara Fuminori, Inokawa Yoshikuni, Takami Hideki, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    CLINICAL EPIGENETICS   Vol. 13 ( 1 ) page: 172   2021.12

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  4. miR-23b-3p Plays an Oncogenic Role in Hepatocellular Carcinoma

    Hayashi Masamichi, Yamada Suguru, Kurimoto Keisuke, Tanabe Hiroshi, Hirabayashi Sho, Sonohara Fuminori, Inokawa Yoshikuni, Takami Hideki, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   Vol. 28 ( 6 ) page: 3416 - 3426   2021.6

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  5. PAX5 gene as a novel methylation marker that predicts both clinical outcome and cisplatin sensitivity in esophageal squamous cell carcinoma.

    Kurimoto K, Hayashi M, Guerrero-Preston R, Koike M, Kanda M, Hirabayashi S, Tanabe H, Takano N, Iwata N, Niwa Y, Takami H, Kobayashi D, Tanaka C, Yamada S, Nakayama G, Sugimoto H, Fujii T, Fujiwara M, Kodera Y

    Epigenetics   Vol. 12 ( 10 ) page: 865 - 874   2017

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1080/15592294.2017.1365207

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  6. An integrated genome-wide approach to discover deregulated microRNAs in non-small cell lung cancer: Clinical significance of miR-23b-3p deregulation.

    Begum S, Hayashi M, Ogawa T, Jabboure FJ, Brait M, Izumchenko E, Tabak S, Ahrendt SA, Westra WH, Koch W, Sidransky D, Hoque MO

    Scientific reports   Vol. 5   page: 13236   2015.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/srep13236

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  7. PAX5 methylation detection by droplet digital PCR for ultra-sensitive deep surgical margins analysis of head and neck squamous cell carcinoma.

    Hayashi M, Guerrero-Preston R, Sidransky D, Koch WM

    Cancer prevention research (Philadelphia, Pa.)     2015.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1158/1940-6207.CAPR-15-0180

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  8. Involvement of epigenetics and EMT-related miRNA in arsenic-induced neoplastic transformation and their potential clinical use.

    Michailidi C, Hayashi M, Datta S, Sen T, Zenner K, Oladeru O, Brait M, Izumchenko E, Baras A, VandenBussche C, Argos M, Bivalacqua TJ, Ahsan H, Hahn NM, Netto GJ, Sidransky D, Hoque MO

    Cancer prevention research (Philadelphia, Pa.)   Vol. 8 ( 3 ) page: 208-21   2015.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1158/1940-6207.CAPR-14-0251

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  9. Milk derived colloid as a novel drug delivery carrier for breast cancer.

    Hayashi M, Silanikove N, Chang X, Ravi R, Pham V, Baia G, Paz K, Brait M, Sidransky D, Koch WM

    Cancer biology & therapy   Vol. 16 ( 8 ) page: 1184-93   2015

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1080/15384047.2015.1056416

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  10. Epigenetic inactivation of VGF associated with Urothelial Cell Carcinoma and its potential as a non-invasive biomarker using urine.

    Hayashi M, Bernert H, Kagohara LT, Maldonado L, Brait M, Schoenberg M, Bivalacqua T, Netto GJ, Koch W, Sidransky D, Hoque MO

    Oncotarget   Vol. 5 ( 10 ) page: 3350-61   2014.5

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  11. Innovative rapid gene methylation analysis of surgical margin tissues in head and neck cancer.

    Hayashi M, Guerrero-Preston R, Okamura J, Michailidi C, Kahn Z, Li X, Ahn J, Goldsmith M, Koch W

    Annals of surgical oncology   Vol. 21 ( 9 ) page: 3124-31   2014.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1245/s10434-014-3661-2

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  12. Clear cell papillary renal cell carcinoma: micro-RNA expression profiling and comparison with clear cell renal cell carcinoma and papillary renal cell carcinoma.

    Munari E, Marchionni L, Chitre A, Hayashi M, Martignoni G, Brunelli M, Gobbo S, Argani P, Allaf M, Hoque MO, Netto GJ

    Human pathology   Vol. 45 ( 6 ) page: 1130-8   2014.6

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.humpath.2014.01.013

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  13. Identification of the collagen type 1 α 1 gene (COL1A1) as a candidate survival-related factor associated with hepatocellular carcinoma.

      Vol. 14   page: 108   2014.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1186/1471-2407-14-108

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  14. Identification of the A Kinase Anchor Protein 12 (AKAP12) Gene as a Candidate Tumor Suppressor of Hepatocellular Carcinoma Reviewed

    Hayashi, M. Nomoto, S. Kanda, M. Okamura, Y. Nishikawa, Y. Yamada, S. Fujii, T. Sugimoto, H. Takeda, S. Kodera, Y.

        page: 381-6   2012.3

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/jso.22135

  15. Expression of cellular retinoic acid binding protein 1 predicts peritoneal recurrence of gastric cancer.

    Sakata K, Kanda M, Shimizu D, Nakamura S, Inokawa Y, Hattori N, Hayashi M, Tanaka C, Nakayama G, Kodera Y

    International journal of oncology   Vol. 60 ( 6 )   2022.6

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    DOI: 10.3892/ijo.2022.5353

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  16. Lysosomal-associated membrane protein family member 5 promotes the metastatic potential of gastric cancer cells

    Umeda Shinichi, Kanda Mitsuro, Shimizu Dai, Nakamura Shunsuke, Sawaki Koichi, Inokawa Yoshikuni, Hattori Norifumi, Hayashi Masamichi, Tanaka Chie, Nakayama Goro, Kodera Yasuhiro

    GASTRIC CANCER   Vol. 25 ( 3 ) page: 558 - 572   2022.5

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  17. Pipeline Esophagogastric Varices Secondary to Extrahepatic Portal Vein Obstruction Treated Endoscopically with the Assistance of Transileocolic Obliteration: A Case Report.

    Yokoyama S, Ishizu Y, Honda T, Imai N, Ito T, Yamamoto K, Komada T, Hayashi M, Ishigami M

    Internal medicine (Tokyo, Japan)     2022.4

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    Language:English  

    DOI: 10.2169/internalmedicine.9404-22

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  18. ASO Visual Abstract: Prognostic Value of a Modified Albumin-Bilirubin Grade Designed for Patients with Esophageal Squamous Cell Carcinoma after Radical Resection.

    Shinozuka T, Kanda M, Shimizu D, Tanaka C, Inokawa Y, Hattori N, Hayashi M, Koike M, Kodera Y

    Annals of surgical oncology     2022.4

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    DOI: 10.1245/s10434-022-11784-x

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  19. Prognostic Value of a Modified Albumin-Bilirubin Score Designed for Patients with Esophageal Squamous Cell Carcinoma After Radical Resection

    Shinozuka Takahiro, Kanda Mitsuro, Shimizu Dai, Tanaka Chie, Inokawa Yoshikuni, Hattori Norifumi, Hayashi Masamichi, Koike Masahiko, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY     2022.4

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  20. Matrix remodeling-associated protein 8 is a marker of a subset of cancer-associated fibroblasts in pancreatic cancer

    Ichihara Ryosuke, Shiraki Yukihiro, Mizutani Yasuyuki, Iida Tadashi, Miyai Yuki, Esaki Nobutoshi, Kato Akira, Mii Shinji, Ando Ryota, Hayashi Masamichi, Takami Hideki, Fujii Tsutomu, Takahashi Masahide, Enomoto Atsushi

    PATHOLOGY INTERNATIONAL   Vol. 72 ( 3 ) page: 161 - 175   2022.3

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  21. Drain Amylase Concentrations at 3 h After Gastrectomy Enhance Early Prediction of Postoperative Peripancreatic Inflammatory Fluid Collection

    Nakanishi Koki, Kanda Mitsuro, Tanaka Chie, Takeda Shigeomi, Tanaka Katsuhito, Shimizu Dai, Inokawa Yoshikuni, Hattori Norifumi, Hayashi Masamichi, Nakayama Goro, Fujiwara Michitaka, Kodera Yasuhiro

    WORLD JOURNAL OF SURGERY   Vol. 46 ( 3 ) page: 648 - 655   2022.3

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  22. Optimal preoperative multidisciplinary treatment in borderline resectable pancreatic cancer: Results of a dual-center study

    Kimura Nana, Yamada Suguru, Takami Hideki, Murotani Kenta, Yoshioka Isaku, Shibuya Kazuto, Sonohara Fuminori, Hoshino Yui, Hirano Katsuhisa, Watanabe Toru, Baba Hayato, Mori Kosuke, Miwa Takeshi, Tanaka Haruyoshi, Kanda Mitsuro, Hayashi Masamichi, Matsui Koshi, Okumura Tomoyuki, Kodera Yasuhiro, Fujii Tsutomu

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 40 ( 4 )   2022.2

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  23. Platelet isoform of phosphofructokinase accelerates malignant features in breast cancer

    Inaishi Takahiro, Shibata Masahiro, Ichikawa Takahiro, Kanda Mitsuro, Hayashi Masamichi, Soeda Ikumi, Takeuchi Dai, Takano Yuko, Tsunoda Nobuyuki, Kodera Yasuhiro, Kikumori Toyone

    ONCOLOGY REPORTS   Vol. 47 ( 1 )   2022.1

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  24. Fish bone migration after pancreaticoduodenectomy: Incidence and treatment options

    Takada Yoshihisa, Ishikawa Takuya, Kawashima Hiroki, Mizutani Yasuyuki, Ohno Eisaburo, Iida Tadashi, Ogawa Hiroshi, Hayashi Masamichi, Takami Hideki, Onoe Shunsuke, Ishigami Masatoshi

    JOURNAL OF DIGESTIVE DISEASES   Vol. 23 ( 1 ) page: 44 - 49   2022.1

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  25. Synopsis of a clinical practice guideline for pancreatic ductal adenocarcinoma with peritoneal dissemination in Japan; Japan Peritoneal Malignancy Study Group.

    Satoi S, Takahara N, Fujii T, Isayama H, Yamada S, Tsuji Y, Miyato H, Yamaguchi H, Yamamoto T, Hashimoto D, Yamaki S, Nakai Y, Saito K, Baba H, Watanabe T, Ishii S, Hayashi M, Kurimoto K, Shimada H, Kitayama J

    Journal of hepato-biliary-pancreatic sciences     2021.12

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    DOI: 10.1002/jhbp.1085

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  26. Neoadjuvant docetaxel, oxaliplatin plus S-1 for treating clinical stage III squamous cell carcinoma of the esophagus: Study protocol of an open-label phase II trial

    Kanda Mitsuro, Shimizu Dai, Miyata Kazushi, Maeda Osamu, Tanaka Chie, Inokawa Yoshikuni, Hattori Norofumi, Hayashi Masamichi, Ando Masahiko, Kuwatsuka Yachiyo, Murotani Kenta, Nakayama Goro, Koike Masahiko, Ando Yuichi, Ebata Tomoki, Kodera Yasuhiro

    CONTEMPORARY CLINICAL TRIALS COMMUNICATIONS   Vol. 24   page: 100853   2021.12

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  27. Synaptotagmin 13 & nbsp;Is Highly Expressed in Estrogen Receptor-Positive Breast Cancer

    Ichikawa Takahiro, Shibata Masahiro, Inaishi Takahiro, Soeda Ikumi, Kanda Mitsuro, Hayashi Masamichi, Takano Yuko, Takeuchi Dai, Tsunoda Nobuyuki, Kodera Yasuhiro, Kikumori Toyone

    CURRENT ONCOLOGY   Vol. 28 ( 5 ) page: 4080 - 4092   2021.10

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  28. Blockade of CHRNB2 signaling with a therapeutic monoclonal antibody attenuates the aggressiveness of gastric cancer cells

    Kanda Mitsuro, Shimizu Dai, Nakamura Shunsuke, Sawaki Koichi, Umeda Shinichi, Miwa Takashi, Tanaka Haruyoshi, Inokawa Yoshikuni, Hattori Norifumi, Hayashi Masamichi, Tanaka Chie, Nakayama Goro, Iguchi Yohei, Katsuno Masahisa, Kodera Yasuhiro

    ONCOGENE   Vol. 40 ( 36 ) page: 5495 - 5504   2021.9

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  29. A Possible Definition of Oligometastasis in Pancreatic Cancer and Associated Survival Outcomes

    Yamanaka Masaya, Hayashi Masamichi, Yamada Suguru, Sonohara Fuminori, Takami Hideki, Inokawa Yoshikuni, Shimizu Dai, Hattori Norifumi, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    ANTICANCER RESEARCH   Vol. 41 ( 8 ) page: 3933 - 3940   2021.8

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  30. G-protein subunit gamma-4 expression has potential for detection, prediction and therapeutic targeting in liver metastasis of gastric cancer

    Tanaka Haruyoshi, Kanda Mitsuro, Miwa Takashi, Umeda Shinichi, Sawaki Koichi, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    BRITISH JOURNAL OF CANCER   Vol. 125 ( 2 ) page: 220 - 228   2021.7

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  31. High Serum Uric Acid Levels Could Be a Risk Factor of Hepatocellular Carcinoma Recurrences

    Hayashi Masamichi, Yamada Suguru, Tanabe Hiroshi, Takami Hideki, Inokawa Yoshikuni, Sonohara Fuminori, Shimizu Dai, Hattori Norifumi, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL   Vol. 73 ( 6 ) page: 996 - 1003   2021.7

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1080/01635581.2020.1779758

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  32. The impact of early tumor shrinkage on conversion surgery and the survival in patients with unresectable locally advanced pancreatic cancer

    Takano Nao, Yamada Suguru, Sonohara Fuminori, Inokawa Yoshikuni, Takami Hideki, Hayashi Masamichi, Koike Masahiko, Fujii Tsutomu, Kodera Yasuhiro

    SURGERY TODAY   Vol. 51 ( 7 ) page: 1099 - 1107   2021.7

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  33. Novel prognostic implications of YTH domain family 2 in resected hepatocellular carcinoma

    Nakagawa Nobuhiko, Sonohara Fuminori, Tanaka Katsuhito, Sunagawa Yuki, Inokawa Yoshikuni, Takami Hideki, Hayashi Masamichi, Yamada Suguru, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    ONCOLOGY LETTERS   Vol. 22 ( 1 ) page: 538   2021.7

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  34. ASO Authors Reflections: miR-23b-3p Plays an Oncogenic Role in Hepatocellular Carcinoma

    Hayashi Masamichi, Yamada Suguru, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   Vol. 28 ( 6 ) page: 3427 - 3428   2021.6

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  35. Endoscopic removal of a fish bone piercing the bile duct after pancreaticoduodenectomy

    Ishikawa Takuya, Kawashima Hiroki, Ohno Eizaburo, Nakamura Masanao, Yamada Suguru, Hayashi Masamichi, Fujishiro Mitsuhiro

    ENDOSCOPY   Vol. 53 ( 05 ) page: E164 - E165   2021.5

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  36. Hepatic metastasis of gastric cancer is associated with enhanced expression of ethanolamine kinase 2 via the p53-Bcl-2 intrinsic apoptosis pathway

    Miwa Takashi, Kanda Mitsuro, Shimizu Dai, Umeda Shinichi, Sawaki Koichi, Tanaka Haruyoshi, Tanaka Chie, Hattori Norifumi, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    BRITISH JOURNAL OF CANCER   Vol. 124 ( 8 ) page: 1449 - 1460   2021.4

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  37. Peritoneal Lavage Tumor DNA as a Novel Biomarker for Predicting Peritoneal Recurrence in Pancreatic Ductal Adenocarcinoma.

    Suenaga M, Fujii T, Yamada S, Hayashi M, Shinjo K, Takami H, Niwa Y, Sonohara F, Shimizu D, Kanda M, Kobayashi D, Tanaka C, Nakayama G, Koike M, Fujiwara M, Kondo Y, Kodera Y

    Annals of surgical oncology   Vol. 28 ( 4 ) page: 2277 - 2286   2021.4

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  38. Conversion surgery in patients with pancreatic cancer and peritoneal metastasis.

    Yamada S, Fujii T, Yamamoto T, Takami H, Yoshioka I, Yamaki S, Sonohara F, Shibuya K, Motoi F, Hirano S, Murakami Y, Inoue H, Hayashi M, Hashimoto D, Murotani K, Kitayama J, Ishikawa H, Kodera Y, Sekimoto M, Satoi S

    Journal of gastrointestinal oncology   Vol. 12 ( Suppl 1 ) page: S110 - S117   2021.4

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    Language:English  

    DOI: 10.21037/jgo-20-243

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  39. Genome-wide identification and characterization of circular RNA in resected hepatocellular carcinoma and background liver tissue

    Sunagawa Yuki, Yamada Suguru, Sonohara Fuminori, Kurimoto Keisuke, Tanaka Nobutake, Suzuki Yunosuke, Inokawa Yoshikuni, Takami Hideki, Hayashi Masamichi, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    SCIENTIFIC REPORTS   Vol. 11 ( 1 ) page: 6016   2021.3

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  40. Impact of Preoperative Occult-Bacterial Translocation on Surgical Site Infection in Patients Undergoing Pancreatoduodenectomy

    Suenaga Masaya, Yokoyama Yukihiro, Fujii Tsutomu, Yamada Suguru, Yamaguchi Junpei, Hayashi Masamichi, Asahara Takashi, Nagino Masato, Kodera Yasuhiro

    JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS   Vol. 232 ( 3 ) page: 298 - 306   2021.3

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  41. STRA6 expression serves as a prognostic biomarker of gastric cancer

    Nakamura Shunsuke, Kanda Mitsuro, Shimizu Dai, Sawaki Koichi, Tanaka Chie, Hattori Norifumi, Hayashi Masamichi, Yamada Suguru, Koike Masahiko, Kodera Yasuhiro

    CANCER SCIENCE   Vol. 112   page: 780 - 780   2021.2

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  42. Function and prognostic value of melanoma-associated antigen-D4 protein in esophageal squamous cell carcinoma

    Sawaki Koichi, Kanda Mitsuro, Sato Yusuke, Shimizu Dai, Uno Yasuo, Umeda Shinichi, Hattori Norifumi, Hayashi Masamichi, Tanaka Chie, Yamada Suguru, Nakayama Goro, Motoyama Satoru, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER SCIENCE   Vol. 112   page: 531 - 531   2021.2

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  43. Development of novel combination cancer immunotherapy using anti-PD-1 and anti-PD-L1 antibody

    Hasegawa Hirotaka, Sugiyama Daisuke, Kanda Mitsuro, Hayashi Masamichi, Tanaka Chie, Yamada Suguru, Nakayama Goro, Koike Masahiko, Nomoto Shuji, Fujiwara Michitaka, Kodera Yasuhiro, Nishikawa Hiroyoshi

    CANCER SCIENCE   Vol. 112   page: 741 - 741   2021.2

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  44. Detection of pancreatic cancer-specific microbiota in pancreatic juice

    Hayashi Masamichi, Yamada Suguru, Kodera Yasuhiro

    CANCER SCIENCE   Vol. 112   page: 760 - 760   2021.2

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  45. Randomised phase II trial of capecitabine plus oxaliplatin with continuous versus intermittent use of oxaliplatin as adjuvant chemotherapy for stage II/III colon cancer (CCOG-1302 study).

    Nakayama G, Takano N, Taniguchi H, Ishigure K, Yokoyama H, Teramoto H, Hashimoto R, Sakai M, Ishiyama A, Kinoshita T, Hayashi N, Nakamura M, Hattori N, Sato Y, Umeda S, Uehara K, Aiba T, Sonohara F, Hayashi M, Kanda M, Kobayashi D, Tanaka C, Yamada S, Koike M, Fujiwara M, Murotani K, Ando M, Ando Y, Muro K, Kodera Y

    European journal of cancer (Oxford, England : 1990)   Vol. 144   page: 61 - 71   2021.2

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    DOI: 10.1016/j.ejca.2020.11.007

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  46. Tissue RNFT2 Expression Levels Are Associated With Peritoneal Recurrence and Poor Prognosis in Gastric Cancer

    Sasahara Masahiro, Kanda Mitsuro, Shimizu Dai, Tanaka Chie, Inokawa Yoshikuni, Hattori Norifumi, Hayashi Masamichi, Nakayama Goro, Kodera Yasuhiro

    ANTICANCER RESEARCH   Vol. 41 ( 2 ) page: 609 - 617   2021.2

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  47. Pancreatic Fat and Body Composition Measurements by Computed Tomography are Associated with Pancreatic Fistula After Pancreatectomy

    Tanaka Katsuhito, Yamada Suguru, Sonohara Fuminori, Takami Hideki, Hayashi Masamichi, Kanda Mitsuro, Kobayashi Daisuke, Tanaka Chie, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   Vol. 28 ( 1 ) page: 530 - 538   2021.1

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1245/s10434-020-08581-9

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  48. Newly developed primary malignancies in long-term survivors who underwent curative esophagectomy for squamous cell carcinoma of the esophagus

    Shimizu Dai, Koike Masahiko, Kanda Mitsuro, Sonohara Fuminori, Hattori Norifumi, Hayashi Masamichi, Tanaka Chie, Yamada Suguru, Kodera Yasuhiro

    SURGERY TODAY   Vol. 51 ( 1 ) page: 153 - 158   2021.1

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00595-020-02072-w

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  49. Impact of Qualitative and Quantitative Biliary Contamination Status on the Incidence of Postoperative Infection Complications in Patients Undergoing Pancreatoduodenectomy.

    Suenaga M, Yokoyama Y, Fujii T, Yamada S, Yamaguchi J, Hayashi M, Asahara T, Nagino M, Kodera Y

    Annals of surgical oncology   Vol. 28 ( 1 ) page: 560 - 569   2021.1

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    DOI: 10.1245/s10434-020-08645-w

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  50. Age-Related Differences in the Prognosis of Pancreatic Cancer According to Perioperative Systemic Therapy

    Sonohara Fuminori, Yamada Suguru, Kurimoto Keisuke, Inokawa Yoshikuni, Takami Hideki, Hayashi Masamichi, Shimizu Dai, Hattori Norifumi, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Fujii Tsutomu, Kodera Yasuhiro

    PANCREAS   Vol. 50 ( 1 ) page: 37 - 46   2021.1

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  51. Perioperative assessment of indocyanine green elimination rate accurately predicts postoperative liver failure in patients undergoing hepatectomy

    Sunagawa Yuki, Yamada Suguru, Kato Yoshiyasu, Sonohara Fuminori, Takami Hideki, Inokawa Yoshikuni, Hayashi Masamichi, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES   Vol. 28 ( 1 ) page: 86 - 94   2021.1

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    DOI: 10.1002/jhbp.833

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  52. Multicenter randomized phase II trial of prophylactic right-half dissection of superior mesenteric artery nerve plexus in pancreatoduodenectomy for pancreatic head cancer

    Yamada Suguru, Satoi Sohei, Takami Hideki, Yamamoto Tomohisa, Yoshioka Isaku, Sonohara Fuminori, Yamaki So, Shibuya Kazuto, Hayashi Masamichi, Hashimoto Daisuke, Ando Masahiko, Murotani Kenta, Sekimoto Mitsugu, Kodera Yasuhiro, Fujii Tsutomu

    ANNALS OF GASTROENTEROLOGICAL SURGERY   Vol. 5 ( 1 ) page: 111 - 118   2021.1

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  53. Different Characteristics of Serum Alfa Fetoprotein and Serum Des-gamma-carboxy Prothrombin in Resected Hepatocellular Carcinoma

    Hayashi Masamichi, Yamada Suguru, Takano Nao, Okamura Yukiyasu, Takami Hideki, Inokawa Yoshikuni, Sonohara Fuminori, Tanaka Nobutake, Shimizu Dai, Hattori Norifumi, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    IN VIVO   Vol. 35 ( 3 ) page: 1749 - 1760   2021

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  54. ASO Authors Reflections: Preoperative Pancreatic Fat and Body Composition Measurements Influence the Incidence of Grade B/C Postoperative Pancreatic Fistula After Pancreatectomy

    Tanaka Katsuhito, Yamada Suguru, Hayashi Masamichi, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   Vol. 27 ( Suppl 3 ) page: 746 - 747   2020.12

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    DOI: 10.1245/s10434-020-08595-3

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  55. Novel Prognostic Implications of Methylated RNA and Demethylases in Resected HCC and Background Liver Tissue

    Nakagawa Nobuhiko, Tanaka Katsuhito, Sonohara Fuminori, Kandimalla Raju, Sunagawa Yuki, Inokawa Yoshikuni, Takami Hideki, Hayashi Masamichi, Yamada Suguru, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    ANTICANCER RESEARCH   Vol. 40 ( 12 ) page: 6665 - 6676   2020.12

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  56. AMIGO2 Expression as a Potential Prognostic Biomarker for Gastric Cancer

    Nakamura Shunsuke, Kanda Mitsuro, Shimizu Dai, Tanaka Chie, Inokawa Yoshikuni, Hattori Norifumi, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Omae Kenji, Koike Masahiko, Kodera Yasuhiro

    ANTICANCER RESEARCH   Vol. 40 ( 12 ) page: 6713 - 6721   2020.12

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  57. An Open-Label Single-Arm Phase II Study of Treatment with Neoadjuvant S-1 Plus Cisplatin for Clinical Stage III Squamous Cell Carcinoma of the Esophagus.

    Kanda M, Koike M, Iwata N, Shimizu D, Tanaka C, Hattori N, Hayashi M, Yamada S, Omae K, Nakayama G, Kodera Y

    The oncologist   Vol. 25 ( 11 ) page: E1650 - E1654   2020.11

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    DOI: 10.1634/theoncologist.2020-0546

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  58. An outcome analysis of predictive factors for portal or splenic vein thrombosis after distal pancreatectomy

    Tanaka Nobutake, Yamada Suguru, Sonohara Fuminori, Takami Hideki, Hayashi Masamichi, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Fujii Tsutomu, Kodera Yasuhiro

    SURGERY TODAY   Vol. 50 ( 10 ) page: 1282 - 1289   2020.10

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    DOI: 10.1007/s00595-020-02004-8

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  59. Characteristics Associated with Nodal and Distant Recurrence after Curative Resection of Squamous Cell Carcinoma of the Thoracic Esophagus

    Kanda Mitsuro, Koike Masahiko, Shimizu Dai, Tanaka Chie, Hayashi Masamichi, Hattori Norifumi, Yamada Suguru, Nakayama Goro, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS   Vol. 231 ( 4 ) page: E121 - E121   2020.10

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  60. Characteristics Associated with Nodal and Distant Recurrence After Radical Esophagectomy for Squamous Cell Carcinoma of the Thoracic Esophagus.

    Kanda M, Koike M, Shimizu D, Tanaka C, Hattori N, Hayashi M, Yamada S, Omae K, Kodera Y

    Annals of surgical oncology   Vol. 27 ( 9 ) page: 3195 - 3205   2020.9

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    DOI: 10.1245/s10434-020-08433-6

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  61. Therapeutic monoclonal antibody targeting of neuronal pentraxin receptor to control metastasis in gastric cancer

    Kanda Mitsuro, Shimizu Dai, Sawaki Koichi, Nakamura Shunsuke, Umeda Shinichi, Miwa Takashi, Tanaka Haruyoshi, Tanaka Chie, Hayashi Masamichi, Iguchi Yohei, Yamada Suguru, Katsuno Masahisa, Kodera Yasuhiro

    MOLECULAR CANCER   Vol. 19 ( 1 ) page: 131   2020.8

  62. Tumor marker recovery rather than major pathological response is a preferable prognostic factor in patients with pancreatic ductal adenocarcinoma with preoperative therapy

    Yamada Suguru, Yokoyama Yukihiro, Sonohara Fuminori, Yamaguchi Junpei, Takami Hideki, Hayashi Masamichi, Onoe Shunsuke, Fujii Tsutomu, Nagino Masato, Kodera Yasuhiro

    JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES   Vol. 27 ( 8 ) page: 487 - 495   2020.8

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    DOI: 10.1002/jhbp.748

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  63. The impact of cancer stem cell markers in the tissues of pancreatic ductal adenocarcinoma for prognosis after surgical resections

    Inokawa Yoshikuni, Yamada Suguru, Hayashi Masamichi, Sunagawa Yuki, Sonohara Fuminori, Takami Hideki, Hattori Norifumi, Kanda Mitsuro, Kobayashi Daisuke, Tanaka Chie, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    CANCER RESEARCH   Vol. 80 ( 16 )   2020.8

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  64. KCNJ15 Expression and Malignant Behavior of Esophageal Squamous Cell Carcinoma.

    Nakamura S, Kanda M, Koike M, Shimizu D, Umeda S, Hattori N, Hayashi M, Tanaka C, Kobayashi D, Yamada S, Omae K, Kodera Y

    Annals of surgical oncology   Vol. 27 ( 7 ) page: 2559 - 2568   2020.7

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    DOI: 10.1245/s10434-019-08189-8

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  65. Novel Prognostic Implications of DUPAN-2 in the Era of Initial Systemic Therapy for Pancreatic Cancer

    Sunagawa Yuki, Yamada Suguru, Sato Yusuke, Morimoto Daishi, Sonohara Fuminori, Takami Hideki, Inokawa Yoshikuni, Hayashi Masamichi, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Fujii Tsutomu, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   Vol. 27 ( 6 ) page: 2081 - 2089   2020.6

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    DOI: 10.1245/s10434-019-07981-w

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  66. Fraser extracellular matrix complex subunit 1 promotes liver metastasis of gastric cancer

    Umeda Shinichi, Kanda Mitsuro, Miwa Takashi, Tanaka Haruyoshi, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    INTERNATIONAL JOURNAL OF CANCER   Vol. 146 ( 10 ) page: 2865 - 2876   2020.5

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    DOI: 10.1002/ijc.32705

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  67. Clinical impact of additional therapy for residual pancreatic cancer.

    Yamada S, Sonohara F, Tashiro M, Murotani K, Takami H, Hayashi M, Kanda M, Tanaka C, Kobayashi D, Nakayama G, Koike M, Fujii T, Kodera Y

    Surgery today   Vol. 50 ( 5 ) page: 440 - 448   2020.5

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    DOI: 10.1007/s00595-019-01900-y

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  68. Optimized Cutoff Value of Serum Squamous Cell Carcinoma Antigen Concentration Accurately Predicts Recurrence After Curative Resection of Squamous Cell Carcinoma of the Esophagus.

    Kanda M, Koike M, Shimizu D, Tanaka C, Kobayashi D, Hattori N, Hayashi M, Omae K, Yamada S, Nakayama G, Kodera Y

    Annals of surgical oncology   Vol. 27 ( 4 ) page: 1233 - 1240   2020.4

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    DOI: 10.1245/s10434-019-07977-6

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  69. Exploration of Exosomal Micro RNA Biomarkers Related to Epithelial-to-Mesenchymal Transition in Pancreatic Cancer

    Sonohara Fuminori, Yamada Suguru, Takeda Shigeomi, Hayashi Masamichi, Suenaga Masaya, Sunagawa Yuki, Tashiro Mitsuru, Takami Hideki, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    ANTICANCER RESEARCH   Vol. 40 ( 4 ) page: 1843 - 1853   2020.4

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    DOI: 10.21873/anticanres.14138

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  70. Clinical Implications of Naples Prognostic Score in Patients with Resected Pancreatic Cancer

    Nakagawa Nobuhiko, Yamada Suguru, Sonohara Fuminori, Takami Hideki, Hayashi Masamichi, Kanda Mitsuro, Kobayashi Daisuke, Tanaka Chie, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   Vol. 27 ( 3 ) page: 887 - 895   2020.3

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    DOI: 10.1245/s10434-019-08047-7

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  71. Predictive value of the modified systemic inflammation score in patients undergoing curative resection of squamous cell carcinoma of the esophagus

    Kanda Mitsuro, Koike Masahiko, Shimizu Dai, Tanaka Chie, Kobayashi Daisuke, Sonohara Fuminori, Takami Hideki, Inokawa Yoshikuni, Hattori Norifumi, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 38 ( 4 ) page: .   2020.2

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  72. Effects of duration of initial treatment on postoperative complications in pancreatic cancer

    Takeda Naoya, Yamada Suguru, Takami Hideki, Sonohara Fuminori, Hayashi Masamichi, Yoshioka Isaku, Shibuya Kazuto, Matsui Koshi, Hirano Katsuhisa, Watanabe Toru, Tohmatsu Yuuko, Kimura Nana, Hojo Shozo, Sawada Shigeaki, Okumura Tomoyuki, Nagata Takuya, Kodera Yasuhiro, Fujii Tsutomu

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 38 ( 4 ) page: .   2020.2

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  73. A prospective trial to evaluate treatment effects of a beta-hydroxy-beta-methylbutyrate containing nutrient for leakage a the anastomotic site after esophagectomy

    Kanda Mitsuro, Koike Masahiko, Fukaya Masahide, Miyata Kazushi, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Murotani Kenta, Fujiwara Michitaka, Nagino Masato, Kodera Yasuhiro

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 82 ( 1 ) page: 33 - 37   2020.2

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    DOI: 10.18999/nagjms.82.1.33

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  74. The Significance of Molecular Biomarkers on Clinical Survival Outcome Differs Depending on Colon Cancer Sidedness

    Hirabayashi Sho, Hayashi Masamichi, Nakayama Goro, Mii Shinji, Hattori Norifumi, Tanabe Hiroshi, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Yamada Suguru, Koike Masahiko, Fujiwara Michitaka, Takahashi Masahide, Kodera Yasuhiro

    ANTICANCER RESEARCH   Vol. 40 ( 1 ) page: 201 - 211   2020.1

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    DOI: 10.21873/anticanres.13941

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  75. Characteristics of Lung Metastasis as an Initial Recurrence Pattern After Curative Resection of Pancreatic Cancer

    Morimoto Daishi, Yamada Suguru, Sonohara Fuminori, Takami Hideki, Hayashi Masamichi, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Fujii Tsutomu, Kodera Yasuhiro

    PANCREAS   Vol. 49 ( 5 ) page: 699 - 705   2020

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  76. STRA6 Expression Serves as a Prognostic Biomarker of Gastric Cancer

    Nakamura Shunsuke, Kanda Mitsuro, Shimizu Dai, Sawaki Kouichi, Tanaka Chie, Hattori Norifumi, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Omae Kenji, Koike Masahiko, Kodera Yasuhiro

    CANCER GENOMICS & PROTEOMICS   Vol. 17 ( 5 ) page: 509 - 516   2020

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  77. Modified Systemic Inflammation Score is Useful for Risk Stratification After Radical Resection of Squamous Cell Carcinoma of the Esophagus.

    Kanda M, Koike M, Tanaka C, Kobayashi D, Hattori N, Hayashi M, Yamada S, Omae K, Fujiwara M, Kodera Y

    Annals of surgical oncology   Vol. 26 ( 13 ) page: 4773 - 4781   2019.12

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    DOI: 10.1245/s10434-019-07914-7

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  78. Tissue Expression of Melanoma-associated Antigen A6 and Clinical Characteristics of Gastric Cancer.

    Endo M, Kanda M, Sawaki K, Shimizu D, Tanaka C, Kobayashi D, Hattori N, Hayashi M, Yamada S, Koike M, Omae K, Kodera Y

    Anticancer research   Vol. 39 ( 11 ) page: 5903 - 5910   2019.11

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    DOI: 10.21873/anticanres.13794

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  79. The levels of SYT13 and CEA mRNAs in peritoneal lavages predict the peritoneal recurrence of gastric cancer

    Nakanishi Koki, Kanda Mitsuro, Umeda Shinichi, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Yamada Suguru, Kodera Yasuhiro

    GASTRIC CANCER   Vol. 22 ( 6 ) page: 1143 - 1152   2019.11

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    DOI: 10.1007/s10120-019-00967-3

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  80. Comparison of non-invasive liver reserve and fibrosis models: Implications for surgery and prognosis for hepatocellular carcinoma

    Sonohara Fuminori, Yamada Suguru, Tanaka Nobutake, Tashiro Mitsuru, Sunagawa Yuki, Morimoto Daishi, Tanaka Haruyoshi, Takami Hideki, Hayashi Masamichi, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    HEPATOLOGY RESEARCH   Vol. 49 ( 11 ) page: 1305 - 1315   2019.11

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    DOI: 10.1111/hepr.13400

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  81. Level of Melanotransferrin in Tissue and Sera Serves as a Prognostic Marker of Gastric Cancer.

    Sawaki K, Kanda M, Umeda S, Miwa T, Tanaka C, Kobayashi D, Hayashi M, Yamada S, Nakayama G, Omae K, Koike M, Kodera Y

    Anticancer research   Vol. 39 ( 11 ) page: 6125 - 6133   2019.11

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    DOI: 10.21873/anticanres.13820

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  82. Expression, Function, and Prognostic Value of MAGE-D4 Protein in Esophageal Squamous Cell Carcinoma

    Uno Yasuo, Kanda Mitsuro, Sato Yusuke, Shimizu Dai, Umeda Shinichi, Hattori Norifumi, Hayashi Masamichi, Tanaka Chie, Kobayashi Daisuke, Yamada Suguru, Nakayama Goro, Motoyama Satoru, Koike Masahiko, Kodera Yasuhiro

    ANTICANCER RESEARCH   Vol. 39 ( 11 ) page: 6015 - 6023   2019.11

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    DOI: 10.21873/anticanres.13807

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  83. Feasibility of subtotal esophagectomy with systematic lymphadenectomy in selected elderly patients with esophageal cancer; a propensity score matching analysis.

    Kanda M, Koike M, Tanaka C, Kobayashi D, Hayashi M, Yamada S, Nakayama G, Omae K, Kodera Y

    BMC surgery   Vol. 19 ( 1 ) page: 143   2019.10

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    DOI: 10.1186/s12893-019-0617-2

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  84. Risk Prediction of Postoperative Pneumonia After Subtotal Esophagectomy Based on Preoperative Serum Cholinesterase Concentrations.

    Kanda M, Koike M, Tanaka C, Kobayashi D, Hayashi M, Yamada S, Omae K, Kodera Y

    Annals of surgical oncology   Vol. 26 ( 11 ) page: 3718 - 3726   2019.10

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    DOI: 10.1245/s10434-019-07512-7

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  85. Novel implications of combined arterial resection for locally advanced pancreatic cancer in the era of newer chemo-regimens

    Sonohara Fuminori, Yamada Suguru, Takami Hideki, Hayashi Masamichi, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Fujii Tsutomu, Kodera Yasuhiro

    EJSO   Vol. 45 ( 10 ) page: 1895 - 1900   2019.10

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    DOI: 10.1016/j.ejso.2019.05.019

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  86. Functions of FRAS1 as a driver gene of liver metastasis from gastric cancer analyzed by the genome editing technology

    Umeda Shinichi, Kanda Mitsuro, Tanaka Haruyoshi, Sonohara Fuminori, Takami Hideki, Hattori Norifumi, Hayashi Masamichi, Tanaka Chie, Kobayashi Daisuke, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER RESEARCH   Vol. 79 ( 13 )   2019.7

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    DOI: 10.1158/1538-7445.AM2019-863

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  87. Albumin-Bilirubin Score Predicts Tolerability to Adjuvant S-1 Monotherapy after Curative Gastrectomy

    Miwa Takashi, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    JOURNAL OF GASTRIC CANCER   Vol. 19 ( 2 ) page: 183 - 192   2019.6

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    DOI: 10.5230/jgc.2019.19.e15

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  88. Effects of duration of initial treatment on postoperative complications in pancreatic cancer

    Yamada Suguru, Takami Hideki, Sonohara Fuminori, Hayashi Masamichi, Fujii Tsutomu, Kodera Yasuhiro

    JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES   Vol. 26 ( 6 ) page: 235 - 241   2019.6

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    DOI: 10.1002/jhbp.622

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  89. Phase II study of chemoradiotherapy combined with gemcitabine plus nab-paclitaxel for unresectable locally advanced pancreatic ductal adenocarcinoma (NUPAT 05 Trial): study protocol for a single arm phase II study.

    Takano N, Yamada S, Hirakawa A, Yokoyama Y, Kawashima H, Maeda O, Okada T, Ohno E, Yamaguchi J, Ishikawa T, Sonohara F, Suenaga M, Takami H, Hayashi M, Niwa Y, Hirooka Y, Ito Y, Naganawa S, Ando Y, Nagino M, Goto H, Fujii T, Kodera Y

    Nagoya journal of medical science   Vol. 81 ( 2 ) page: 233 - 239   2019.5

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    DOI: 10.18999/nagjms.81.2.233

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  90. Increased Expression of DNAJC12 is Associated with Aggressive Phenotype of Gastric Cancer

    Uno Yasuo, Kanda Mitsuro, Miwa Takashi, Umeda Shinichi, Tanaka Haruyoshi, Tanaka Chie, Kobayashi Daisuke, Suenaga Masaya, Hattori Norifumi, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Fujiwara Michitaka, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   Vol. 26 ( 3 ) page: 836 - 844   2019.3

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    DOI: 10.1245/s10434-018-07149-y

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  91. Biological and conditional factors should be included when defining criteria for resectability for patients with pancreatic cancer.

    Kato Y, Yamada S, Tashiro M, Sonohara F, Takami H, Hayashi M, Kanda M, Kobayashi D, Tanaka C, Nakayama G, Koike M, Fujiwara M, Kodera Y

    HPB : the official journal of the International Hepato Pancreato Biliary Association     2019.2

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    DOI: 10.1016/j.hpb.2019.01.012

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  92. Prediction of peritoneal recurrences of gastric cancer by qPCR analysis of peritoneal lavage fluids.

    Nakanishi Koki, Kanda Mitsuro, Umeda Shinichi, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 37 ( 4 ) page: .   2019.2

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  93. Homeobox C10 Influences on the Malignant Phenotype of Gastric Cancer Cell Lines and its Elevated Expression Positively Correlates with Recurrence and Poor Survival.

    Miwa T, Kanda M, Umeda S, Tanaka H, Tanaka C, Kobayashi D, Suenaga M, Hayashi M, Yamada S, Nakayama G, Koike M, Kodera Y

    Annals of surgical oncology     2019.1

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    DOI: 10.1245/s10434-019-07166-5

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  94. Identification of a serum-based miRNA signature for response of esophageal squamous cell carcinoma to neoadjuvant chemotherapy

    Niwa Yukiko, Yamada Suguru, Sonohara Fuminori, Kurimoto Keisuke, Hayashi Masamichi, Tashiro Mitsuru, Iwata Naoki, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF TRANSLATIONAL MEDICINE   Vol. 17 ( 1 ) page: 1   2019.1

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    DOI: 10.1186/s12967-018-1762-6

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  95. Optical trocar access for initial trocar placement in laparoscopic gastrointestinal surgery: A propensity score-matching analysis

    Tanaka Chie, Fujiwara Michitaka, Kanda Mitsuro, Murotani Kenta, Iwata Naoki, Hayashi Masamichi, Kobayashi Daisuke, Yamada Suguru, Kodera Yasuhiro

    ASIAN JOURNAL OF ENDOSCOPIC SURGERY   Vol. 12 ( 1 ) page: 37 - 42   2019.1

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    DOI: 10.1111/ases.12484

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  96. Perioperative and prognostic implication of albumin-bilirubin-TNM score in Child-Pugh class A hepatocellular carcinoma

    Sonohara Fuminori, Yamada Suguru, Tanaka Nobutake, Suenaga Masaya, Takami Hideki, Hayashi Masamichi, Niwa Yukiko, Sugimoto Hiroyuki, Hattori Norifumi, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    ANNALS OF GASTROENTEROLOGICAL SURGERY   Vol. 3 ( 1 ) page: 65-74   2019.1

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    DOI: 10.1002/ags3.12212

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  97. Establishment of Peritoneal and Hepatic Metastasis Mouse Xenograft Models Using Gastric Cancer Cell Lines

    Miwa Takashi, Kanda Mitsuro, Umeda Shinichi, Tanaka Haruyoshi, Shimizu Dai, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    IN VIVO   Vol. 33 ( 6 ) page: 1785 - 1792   2019

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    DOI: 10.21873/invivo.11669

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  98. Troponin I2 as a specific biomarker for prediction of peritoneal metastasis in gastric cancer

    Sawaki Koichi, Kanda Mitsuro, Suenaga Masaya, Hayashi Masamichi, Tanaka Chie, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER SCIENCE   Vol. 109   page: 765-765   2018.12

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  99. RASEF expression correlates with hormone receptor status in breast cancer

    Shibata Masahiro, Kanda Mitsuro, Shimizu Dai, Tanaka Haruyoshi, Umeda Shinichi, Miwa Takashi, Hayashi Masamichi, Inaishi Takahiro, Miyajima Noriyuki, Adachi Yayoi, Takano Yuko, Nakanishi Kenichi, Takeuchi Dai, Noda Sumiyo, Kodera Yasuhiro, Kikumori Toyone

    ONCOLOGY LETTERS   Vol. 16 ( 6 ) page: 7223 - 7230   2018.12

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    DOI: 10.3892/ol.2018.9542

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  100. Pattern-specific Transcriptomics Identifies ASGR2 as a Predictor of Hematogenous Recurrence of Gastric Cancer

    Tanaka Haruyoshi, Kanda Mitsuro, Suenaga Masaya, Hayashi Masamichi, Tanaka Chie, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER SCIENCE   Vol. 109   page: 1128-1128   2018.12

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  101. Molecular surgical margin analysis of pancreatic cancer surgeries

    Hayashi Masamichi, Yamada Suguru, Suenaga Masaya, Kodera Yasuhiro

    CANCER SCIENCE   Vol. 109   page: 1419-1419   2018.12

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  102. Integrated multigene expression panel to prognosticate patients with gastric cancer

    Kanda Mitsuro, Miwa Takashi, Umeda Shinichi, Tanaka Chie, Hayashi Masamichi, Suenaga Masaya, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER SCIENCE   Vol. 109   page: 769-769   2018.12

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  103. Copine 5 expression predicts prognosis following curative resection of esophageal squamous cell carcinoma

    Umeda Shinichi, Kanda Mitsuro, Koike Masahiko, Tanaka Haruyoshi, Miwa Takashi, Tanaka Chie, Kobayashi Daisuke, Suenaga Masaya, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Kodera Yasuhiro

    ONCOLOGY REPORTS   Vol. 40 ( 6 ) page: 3772 - 3780   2018.12

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    DOI: 10.3892/or.2018.6742

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  104. A New Biomarker for Peritoneal Lavage Using Digital PCR in Patients with Pancreatic Ductal Adenocarcinoma

    Suenaga Masaya, Yamada Suguru, Hayashi Masamichi, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER SCIENCE   Vol. 109   page: 650-650   2018.12

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  105. Treatment strategy of intraperitoneal and systemic chemotherapy combined with gastrectomy for gastric cancer with peritoneal metastasis

    Kobayashi Daisuke, Kanda Mitsuro, Tanaka Chie, Sonohara Fuminori, Suenaga Masaya, Takami Hideki, Hattori Norifumi, Niwa Yukiko, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 33   page: 98-98   2018.11

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  106. Clinical Impact of Neoadjuvant Therapy on Nutritional Status in Pancreatic Cancer

    Tashiro Mitsuru, Yamada Suguru, Sonohara Fuminori, Takami Hideki, Suenaga Masaya, Hayashi Masamichi, Niwa Yukiko, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Fujii Tsutomu, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   Vol. 25 ( 11 ) page: 3365 - 3371   2018.10

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    DOI: 10.1245/s10434-018-6699-8

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  107. Significance of Preoperative Systemic Inflammation Score in Short-Term and Long-Term Outcomes of Patients with Pathological T2-4 Gastric Cancer After Radical Gastrectomy

    Sato Bin, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Iwata Naoki, Hattori Norifumi, Suenaga Masaya, Hayashi Masamichi, Yamada Suguru, Murotani Kenta, Fujiwara Michitaka, Kodera Yasuhiro

    WORLD JOURNAL OF SURGERY   Vol. 42 ( 10 ) page: 3277-3285   2018.10

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    DOI: 10.1007/s00268-018-4597-7

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  108. Expression of sushi domain containing two reflects the malignant potential of gastric cancer

    Umeda Shinichi, Kanda Mitsuro, Miwa Takashi, Tanaka Haruyoshi, Tanaka Chie, Kobayashi Daisuke, Suenaga Masaya, Hattori Norifumi, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER MEDICINE   Vol. 7 ( 10 ) page: 5194 - 5204   2018.10

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    DOI: 10.1002/cam4.1793

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  109. SYT7 acts as a driver of hepatic metastasis formation of gastric cancer cells

    Kanda Mitsuro, Tanaka Haruyoshi, Shimizu Dai, Miwa Takashi, Umeda Shinichi, Tanaka Chie, Kobayashi Daisuke, Hattori Norifumi, Suenaga Masaya, Hayashi Masamichi, Iwata Naoki, Yamada Suguru, Fujiwara Michitaka, Kodera Yasuhiro

    ONCOGENE   Vol. 37 ( 39 ) page: 5355 - 5366   2018.9

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    DOI: 10.1038/s41388-018-0335-8

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  110. Comparison of the Survival Outcomes of Pancreatic Cancer and Intraductal Papillary Mucinous Neoplasms.

    Yamada S, Fujii T, Hirakawa A, Takami H, Suenaga M, Hayashi M, Niwa Y, Hattori N, Iwata N, Kanda M, Tanaka C, Kobayashi D, Nakayama G, Koike M, Fujiwara M, Kodera Y

    Pancreas   Vol. 47 ( 8 ) page: 974 - 979   2018.9

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    DOI: 10.1097/MPA.0000000000001110

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  111. Synaptotagmin XIII expression and peritoneal metastasis in gastric cancer

    Kanda M., Shimizu D., Tanaka H., Tanaka C., Kobayashi D., Hayashi M., Takami H., Niwa Y., Yamada S., Fujii T., Sugimoto H., Kodera Y.

    BRITISH JOURNAL OF SURGERY   Vol. 105 ( 10 ) page: 1349-1358   2018.9

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    DOI: 10.1002/bjs.10876

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  112. Pattern-Specific Transcriptomics Identifies ASGR2 as a Predictor of Hematogenous Recurrence of Gastric Cancer

    Tanaka Haruyoshi, Kanda Mitsuro, Miwa Takashi, Tanaka Chie, Kobayashi Daisuke, Umeda Shinichi, Shibata Masahiro, Suenaga Masaya, Hattori Norifumi, Hayashi Masamichi, Iwata Naoki, Yamada Suguru, Nakayama Goro, Fujiwara Michitaka, Kodera Yasuhiro

    MOLECULAR CANCER RESEARCH   Vol. 16 ( 9 ) page: 1420 - 1429   2018.9

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    DOI: 10.1158/1541-7786.MCR-17-0467

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  113. Impact of the Controlling Nutritional Status Score on the Prognosis After Curative Resection of Pancreatic Ductal Adenocarcinoma

    Kato Yoshiyasu, Yamada Suguru, Suenaga Masaya, Takami Hideki, Niwa Yukiko, Hayashi Masamichi, Iwata Naoki, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    PANCREAS   Vol. 47 ( 7 ) page: 823 - 829   2018.8

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    DOI: 10.1097/MPA.0000000000001105

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  114. Troponin I2 as a Specific Biomarker for Prediction of Peritoneal Metastasis in Gastric Cancer

    Sawaki Koichi, Kanda Mitsuro, Miwa Takashi, Umeda Shinichi, Tanaka Haruyoshi, Tanaka Chie, Kobayashi Daisuke, Suenaga Masaya, Hattori Norifumi, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Fujiwara Michitaka, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   Vol. 25 ( 7 ) page: 2083 - 2090   2018.7

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    DOI: 10.1245/s10434-018-6480-z

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  115. Molecular surgical margin analysis of pancreatic cancers

    Hayashi Masamichi, Yamada Suguru, Tanabe Hiroshi, Kato Yoshiyasu, Tanaka Katsuhito, Tashiro MItsuru, Tanaka Haruyoshi, Asano Tomonari, Takami Hideki, Suenaga Masaya, Niwa Yukiko, Kodera Yasuhiro

    CANCER RESEARCH   Vol. 78 ( 13 )   2018.7

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    DOI: 10.1158/1538-7445.AM2018-3330

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  116. Clinical Implications of Lysyl Oxidase-Like Protein 2 Expression in Pancreatic Cancer

    Tanaka Nobutake, Yamada Suguru, Sonohara Fuminori, Suenaga Masaya, Hayashi Masamichi, Takami Hideki, Niwa Yukiko, Hattori Norifumi, Iwata Naoki, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Fujii Tsutomu, Kodera Yasuhiro

    SCIENTIFIC REPORTS   Vol. 8 ( 1 ) page: 9846   2018.6

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    DOI: 10.1038/s41598-018-28253-9

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  117. A novel dual-marker expression panel for easy and accurate risk stratification of patients with gastric cancer

    Kanda Mitsuro, Murotani Kenta, Tanaka Haruyoshi, Miwa Takashi, Umeda Shinichi, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Hattori Norifumi, Suenaga Masaya, Yamada Suguru, Nakayama Goro, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER MEDICINE   Vol. 7 ( 6 ) page: 2463-2471   2018.6

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    DOI: 10.1002/cam4.1522

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  118. Significance of Lysyl oxidase-like 2 gene expression on the epithelial-mesenchymal status of hepatocellular carcinoma

    Ninomiya Go, Yamada Suguru, Hayashi Masamichi, Takeda Shigeomi, Suenaga Masaya, Takami Hideki, Kanda Mitsuro, Iwata Naoki, Niwa Yukiko, Tanaka Chie, Kobayashi Daisuke, Fujii Tsutomu, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    ONCOLOGY REPORTS   Vol. 39 ( 6 ) page: 2664 - 2672   2018.6

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    DOI: 10.3892/or.2018.6349

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  119. IDENTIFICATION OF MOLECULES DRIVING HEPATIC METASTASIS FORMATION OF GASTRIC CANCER CELLS

    Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Suenaga Masaya, Takami Hideki, Hattori Norifumi, Niwa Yukiko, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    GUT   Vol. 67   page: A5-A5   2018.6

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    DOI: 10.1136/gutjnl-2018-IDDFabstracts.12

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  120. Phase I study of chemoradiotherapy using gemcitabine plus nab-paclitaxel for unresectable locally advanced pancreatic cancer

    Yamada Suguru, Fujii Tsutomu, Yokoyama Yukihiro, Kawashima Hiroki, Maeda Osamu, Suzuki Kojiro, Okada Tohru, Ono Eizaburo, Yamaguchi Junpei, Takano Nao, Takami Hideki, Hayashi Masamichi, Niwa Yukiko, Hirooka Yoshiki, Ito Yoshiyuki, Naganawa Shinji, Ando Yuichi, Nagino Masato, Goto Hidemi, Kodera Yasuhiro

    CANCER CHEMOTHERAPY AND PHARMACOLOGY   Vol. 81 ( 5 ) page: 815 - 821   2018.5

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    DOI: 10.1007/s00280-018-3554-3

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  121. Integrated multigene expression panel to prognosticate patients with gastric cancer.

    Kanda M, Murotani K, Tanaka H, Miwa T, Umeda S, Tanaka C, Kobayashi D, Hayashi M, Hattori N, Suenaga M, Yamada S, Nakayama G, Fujiwara M, Kodera Y

    Oncotarget   Vol. 9 ( 27 ) page: 18775-18785   2018.4

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    DOI: 10.18632/oncotarget.24661

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  122. Significance of SYT8 For the Detection, Prediction, and Treatment of Peritoneal Metastasis From Gastric Cancer.

    Kanda M, Shimizu D, Tanaka H, Tanaka C, Kobayashi D, Hayashi M, Iwata N, Niwa Y, Yamada S, Fujii T, Sugimoto H, Murotani K, Fujiwara M, Kodera Y

    Annals of surgery   Vol. 267 ( 3 ) page: 495 - 503   2018.3

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    DOI: 10.1097/SLA.0000000000002096

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  123. Preoperative Albumin-Bilirubin Grade Predicts Recurrences After Radical Gastrectomy in Patients with pT2-4 Gastric Cancer.

    Kanda M, Tanaka C, Kobayashi D, Uda H, Inaoka K, Tanaka Y, Hayashi M, Iwata N, Yamada S, Fujii T, Sugimoto H, Murotani K, Fujiwara M, Kodera Y

    World journal of surgery   Vol. 42 ( 3 ) page: 773 - 781   2018.3

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    DOI: 10.1007/s00268-017-4234-x

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  124. Clinical implication of nutrition for neoadjuvant therapy and impact of nutritional support in pancreatic cancer.

    Tashiro Mitsuru, Yamada Suguru, Fujii Tsutomu, Hattori Norifumi, Takami Hideki, Suenaga Masaya, Niwa Yukiko, Hayashi Masamichi, Iwata Naoki, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 36 ( 4 ) page: .   2018.2

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  125. Phase I study of chemoradiotherapy using gemcitabine plus nab-paclitaxel for unresectable locally advanced pancreatic cancer.

    Yamada Suguru, Fujii Tsutomu, Takano Nao, Takami Hideki, Suenaga Masaya, Niwa Yukiko, Hayashi Masamichi, Iwata Naoki, Kanda Mitsuro, Kobayashi Daisuke, Tanaka Chie, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 36 ( 4 ) page: .   2018.2

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  126. Identification of a novel molecule target for the diagnosis, prediction, and treatment of hepatic metastasis of gastric cancer.

    Kanda Mitsuro, Tanaka Haruyoshi, Miwa Takashi, Kobayashi Daisuke, Tanaka Chie, Takami Hideki, Hayashi Masamichi, Iwata Naoki, Niwa Yukiko, Yamada Suguru, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 36 ( 4 ) page: .   2018.2

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  127. Perioperative Serum Carcinoembryonic Antigen Levels Predict Recurrence and Survival of Patients with Pathological T2-4 Gastric Cancer Treated with Curative Gastrectomy.

    Uda H, Kanda M, Tanaka C, Kobayashi D, Inaoka K, Tanaka Y, Hayashi M, Iwata N, Yamada S, Fujii T, Sugimoto H, Murotani K, Fujiwara M, Kodera Y

    Digestive surgery   Vol. 35 ( 1 ) page: 55 - 63   2018

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    DOI: 10.1159/000471931

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  128. Prognostic Impact of Portal System Invasion in Pancreatic Cancer Based on Image Classification

    Morimoto Daishi, Yamada Suguru, Murotani Kenta, Sonohara Fuminori, Takami Hideki, Suenaga Masaya, Hayashi Masamichi, Niwa Yukiko, Tashiro Mitsuru, Hattori Norifumi, Iwata Naoki, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Fujii Tsutomu, Kodera Yasuhiro

    PANCREAS   Vol. 47 ( 10 ) page: 1350-1356   2018

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    DOI: 10.1097/MPA.0000000000001186

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  129. Prognostic Value of Long Non-Coding RNA HULC and MALAT1 Following the Curative Resection of Hepatocellular Carcinoma.

    Sonohara F, Inokawa Y, Hayashi M, Yamada S, Sugimoto H, Fujii T, Kodera Y, Nomoto S

    Scientific reports   Vol. 7 ( 1 ) page: 16142   2017.11

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    DOI: 10.1038/s41598-017-16260-1

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  130. FBXO50 Enhances the Malignant Behavior of Gastric Cancer Cells.

    Miwa T, Kanda M, Tanaka H, Tanaka C, Kobayashi D, Umeda S, Iwata N, Hayashi M, Yamada S, Fujii T, Fujiwara M, Kodera Y

    Annals of surgical oncology   Vol. 24 ( 12 ) page: 3771-3779   2017.11

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    DOI: 10.1245/s10434-017-5882-7

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  131. Identification of <i>NCCRP1</i> as an epigenetically regulated tumor suppressor and biomarker for malignant phenotypes of squamous cell carcinoma of the esophagus.

    Miwa T, Kanda M, Koike M, Iwata N, Tanaka H, Umeda S, Tanaka C, Kobayashi D, Hayashi M, Yamada S, Fujii T, Fujiwara M, Kodera Y

    Oncology letters   Vol. 14 ( 4 ) page: 4822-4828   2017.10

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    DOI: 10.3892/ol.2017.6753

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  132. Evaluation and proposal of novel resectability criteria for pancreatic cancer established by the Japan Pancreas Society.

    Yamada S, Fujii T, Takami H, Hayashi M, Iwata N, Kanda M, Tanaka C, Sugimoto H, Nakayama G, Koike M, Fujiwara M, Kodera Y

    Surgery   Vol. 162 ( 4 ) page: 784-791   2017.10

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    DOI: 10.1016/j.surg.2017.04.023

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  133. An integrated multigene expression panel to predict long-term survival after curative hepatectomy in patients with hepatocellular carcinoma.

    Kanda M, Murotani K, Sugimoto H, Miwa T, Umeda S, Suenaga M, Hayashi M, Hattori N, Tanaka C, Kobayashi D, Yamada S, Fujiwara M, Kodera Y

    Oncotarget   Vol. 8 ( 41 ) page: 71070 - 71079   2017.9

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    DOI: 10.18632/oncotarget.20369

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  134. Downregulation of GPR155 as a prognostic factor after curative resection of hepatocellular carcinoma.

    Umeda S, Kanda M, Sugimoto H, Tanaka H, Hayashi M, Yamada S, Fujii T, Takami H, Niwa Y, Iwata N, Tanaka C, Kobayashi D, Fujiwara M, Kodera Y

    BMC cancer   Vol. 17 ( 1 ) page: 610   2017.9

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    DOI: 10.1186/s12885-017-3629-2

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  135. MicroRNA expression profiling of Xp11 renal cell carcinoma.

    Marchionni L, Hayashi M, Guida E, Ooki A, Munari E, Jabboure FJ, Dinalankara W, Raza A, Netto GJ, Hoque MO, Argani P

    Human pathology   Vol. 67   page: 18 - 29   2017.9

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    DOI: 10.1016/j.humpath.2017.03.011

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  136. Overexpression of Derlin 3 is associated with malignant phenotype of breast cancer cells.

    Shibata M, Kanda M, Tanaka H, Umeda S, Miwa T, Shimizu D, Hayashi M, Inaishi T, Miyajima N, Adachi Y, Takano Y, Nakanishi K, Takeuchi D, Noda S, Kodera Y, Kikumori T

    Oncology reports   Vol. 38 ( 3 ) page: 1760-1766   2017.9

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    DOI: 10.3892/or.2017.5800

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  137. Involvement of the immunoregulator MZB1 in progression of gastric cancer

    Tanaka Y., Kanda M., Tanaka C., Kobayashi D., Tanaka H., Takami H., Hayashi M., Iwata N., Niwa Y., Yamada S., Nakayama G., Sugimoto H., Koike M., Fujiwara M., Kodera Y.

    ANNALS OF ONCOLOGY   Vol. 28   page: .   2017.9

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  138. Early detection of gastric cancer using global, genome-wide and IRF4, ELMO1, CLIP4 and MSC DNA methylation in endoscopic biopsies.

    Oncotarget   Vol. 8 ( 24 ) page: 38501 - 38516   2017.6

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    DOI: 10.18632/oncotarget.16258

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  139. Expression of regulatory factor X1 can predict the prognosis of breast cancer.

    Shibata M, Kanda M, Shimizu D, Tanaka H, Umeda S, Hayashi M, Inaishi T, Miyajima N, Adachi Y, Takano Y, Nakanishi K, Takeuchi D, Noda S, Kodera Y, Kikumori T

    Oncology letters   Vol. 13 ( 6 ) page: 4334-4340   2017.6

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    DOI: 10.3892/ol.2017.6005

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  140. Epigenetic modulation associated with carcinogenesis and prognosis of human gastric cancer.

    Sonohara F, Inokawa Y, Hayashi M, Kodera Y, Nomoto S

    Oncology letters   Vol. 13 ( 5 ) page: 3363 - 3368   2017.5

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    DOI: 10.3892/ol.2017.5912

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  141. Clinical implication of Frizzled 2 expression and its association with epithelial-to-mesenchymal transition in hepatocellular carcinoma.

    Asano T, Yamada S, Fuchs BC, Takami H, Hayashi M, Sugimoto H, Fujii T, Tanabe KK, Kodera Y

    International journal of oncology   Vol. 50 ( 5 ) page: 1647 - 1654   2017.5

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    DOI: 10.3892/ijo.2017.3937

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  142. Clinical utility of the platelet-lymphocyte ratio as a predictor of postoperative complications after radical gastrectomy for clinical T2-4 gastric cancer.

    Inaoka K, Kanda M, Uda H, Tanaka Y, Tanaka C, Kobayashi D, Takami H, Iwata N, Hayashi M, Niwa Y, Yamada S, Fujii T, Sugimoto H, Murotani K, Fujiwara M, Kodera Y

    World journal of gastroenterology   Vol. 23 ( 14 ) page: 2519 - 2526   2017.4

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    DOI: 10.3748/wjg.v23.i14.2519

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  143. The efficacy and safety of CapeOX plus bevacizumab therapy followed by capecitabine plus bevacizumab maintenance therapy in patients with metastatic colorectal cancer: a multi-center, single-arm, phase II study (CCOG-0902).

    Nakayama G, Ishigure K, Yokoyama H, Uehara K, Kojima H, Ishiyama A, Hayashi N, Takano N, Hattori N, Kobayashi D, Tanaka C, Hayashi M, Kanda M, Yamada S, Sugimoto H, Koike M, Fujiwara M, Fujii T, Murotani K, Ando Y, Kodera Y

    BMC cancer   Vol. 17 ( 1 ) page: 243   2017.4

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    DOI: 10.1186/s12885-017-3245-1

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  144. Expression of GULP1 in bronchial epithelium is associated with the progression of emphysema in chronic obstructive pulmonary disease.

    Datta S, Nam HS, Hayashi M, Maldonado L, Goldberg R, Brait M, Sidransky D, Illei P, Baras A, Vij N, Hoque MO

    Respiratory medicine   Vol. 124   page: 72 - 78   2017.3

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    DOI: 10.1016/j.rmed.2017.02.011

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  145. GPR155 Serves as a Predictive Biomarker for Hematogenous Metastasis in Patients with Gastric Cancer. Reviewed

    Shimizu D, Kanda M, Tanaka H, Kobayashi D, Tanaka C, Hayashi M, Iwata N, Niwa Y, Takami H, Yamada S, Fujii T, Nakayama G, Fujiwara M, Kodera Y

    Scientific reports   Vol. 7   page: 42089   2017.2

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    DOI: 10.1038/srep42089

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  146. Clinical impact of sarcopenia on prognosis in pancreatic ductal adenocarcinoma.

    Ninomiya Go, Fujii Tsutomu, Yamada Suguru, Asano Tomonari, Takano Nao, Takami Hideki, Iwata Naoki, Kanda Mitsuro, Niwa Yukiko, Hayashi Masamichi, Kobayashi Daisuke, Tanaka Chie, Nakayama Goro, Sugimoto Hiroyuki, Fujiwara Michitaka, Koike Masahiko, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 35 ( 4 ) page: .   2017.2

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  147. Inverse probability of treatment weighting analysis of upfront surgery versus neoadjuvant chemoradiotherapy followed by surgery for pancreatic adenocarcinoma with arterial abutment.

    Fujii Tsutomu, Yamada Suguru, Murotani Kenta, Takami Hideki, Hayashi Masamichi, Kanda Mitsuro, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 35 ( 4 ) page: .   2017.2

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  148. Conversion surgery for unresectable gastric cancer following complete response of distant metastasis by systemic chemotherapy.

    Kobayashi Daisuke, Kanda Mitsuro, Tanaka Chie, Iwata Naoki, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujii Tsutomu, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 35 ( 4 ) page: .   2017.2

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  149. Clinical implication of inflammation-based prognostic score and perioperative nutrition control in pancreatic cancer.

    Takano Nao, Yamada Suguru, Fujii Tsutomu, Tashiro Mitsuru, Tanaka Nobutake, Morimoto Daishi, Ninomiya Go, Niwa Yukiko, Takami Hideki, Iwata Naoki, Hayashi Masamichi, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 35 ( 4 ) page: .   2017.2

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  150. Proposal of the Coagulation Score as a Predictor for Short-Term and Long-Term Outcomes of Patients with Resectable Gastric Cancer.

    Kanda M, Tanaka C, Kobayashi D, Mizuno A, Tanaka Y, Takami H, Iwata N, Hayashi M, Niwa Y, Yamada S, Fujii T, Sugimoto H, Murotani K, Fujiwara M, Kodera Y

    Annals of surgical oncology   Vol. 24 ( 2 ) page: 502 - 509   2017.2

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    DOI: 10.1245/s10434-016-5544-1

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  151. The protein arginine methyltransferase 5 promotes malignant phenotype of hepatocellular carcinoma cells and is associated with adverse patient outcomes after curative hepatectomy.

    Shimizu D, Kanda M, Sugimoto H, Shibata M, Tanaka H, Takami H, Iwata N, Hayashi M, Tanaka C, Kobayashi D, Yamada S, Nakayama G, Koike M, Fujiwara M, Fujii T, Kodera Y

    International journal of oncology   Vol. 50 ( 2 ) page: 381-386   2017.2

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    DOI: 10.3892/ijo.2017.3833

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  152. Stapling an extracorporeal Billroth-I anastomosis by the complete double stapling technique after laparoscopy-assisted distal gastrectomy.

    Tanaka C, Fujiwara M, Kanda M, Murotani K, Iwata N, Hayashi M, Kobayashi D, Yamada S, Nakayama G, Sugimoto H, Koike M, Fujii T, Kodera Y

    Asian journal of endoscopic surgery     2017.1

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    DOI: 10.1111/ases.12357

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  153. Clinical impact of sarcopenia on prognosis in pancreatic ductal adenocarcinoma: A retrospective cohort study.

    Ninomiya G, Fujii T, Yamada S, Yabusaki N, Suzuki K, Iwata N, Kanda M, Hayashi M, Tanaka C, Nakayama G, Sugimoto H, Koike M, Fujiwara M, Kodera Y

    International journal of surgery (London, England)   Vol. 39   page: 45-51   2017.1

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    DOI: 10.1016/j.ijsu.2017.01.075

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  154. Epigenetic suppression of the immunoregulator MZB1 is associated with the malignant phenotype of gastric cancer.

    Kanda M, Tanaka C, Kobayashi D, Tanaka H, Shimizu D, Shibata M, Takami H, Hayashi M, Iwata N, Niwa Y, Yamada S, Fujii T, Nakayama G, Fujiwara M, Kodera Y

    International journal of cancer   Vol. 139 ( 10 ) page: 2290-8   2016.11

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    DOI: 10.1002/ijc.30286

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  155. Molecular alterations in the carcinogenesis and progression of hepatocellular carcinoma: Tumor factors and background liver factors.

    Inokawa Y, Inaoka K, Sonohara F, Hayashi M, Kanda M, Nomoto S

    Oncology letters   Vol. 12 ( 5 ) page: 3662-3668   2016.11

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    DOI: 10.3892/ol.2016.5141

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  156. FAM46C Serves as a Predictor of Hepatic Recurrence in Patients with Resectable Gastric Cancer.

    Tanaka H, Kanda M, Shimizu D, Tanaka C, Kobayashi D, Hayashi M, Iwata N, Yamada S, Fujii T, Nakayama G, Sugimoto H, Fujiwara M, Niwa Y, Kodera Y

    Annals of surgical oncology     2016.10

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1245/s10434-016-5636-y

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  157. Usefulness of preoperative estimated glomerular filtration rate to predict complications after curative gastrectomy in patients with clinical T2-4 gastric cancer.

    Tanaka Y, Kanda M, Tanaka C, Kobayashi D, Mizuno A, Iwata N, Hayashi M, Niwa Y, Takami H, Yamada S, Fujii T, Nakayama G, Sugimoto H, Fujiwara M, Kodera Y

    Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association     2016.10

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s10120-016-0657-6

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  158. Modified two-dimensional response as surrogate marker of overall survival in patients with metastatic colorectal cancer.

    Nakayama G, Fujii T, Murotani K, Uehara K, Hattori N, Hayashi M, Tanaka C, Kobayashi D, Kanda M, Yamada S, Sugimoto H, Koike M, Fujiwara M, Ando Y, Kodera Y

    Cancer science   Vol. 107 ( 10 ) page: 1492-1498   2016.10

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/cas.13023

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  159. Correlation Between Poor Prognosis and Lower TPPP Gene Expression in Hepatocellular Carcinoma.

    Inokawa Y, Sonohara F, Kanda M, Hayashi M, Nishikawa Y, Sugimoto H, Kodera Y, Nomoto S

    Anticancer research   Vol. 36 ( 9 ) page: 4639-45   2016.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.21873/anticanres.11014

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  160. Protein arginine methyltransferase 5 is associated with malignant phenotype and peritoneal metastasis in gastric cancer.

    Kanda M, Shimizu D, Fujii T, Tanaka H, Shibata M, Iwata N, Hayashi M, Kobayashi D, Tanaka C, Yamada S, Nakayama G, Sugimoto H, Koike M, Fujiwara M, Kodera Y

    International journal of oncology   Vol. 49 ( 3 ) page: 1195-202   2016.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3892/ijo.2016.3584

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  161. Nutritional predictors for postoperative short-term and long-term outcomes of patients with gastric cancer.

    Kanda M, Mizuno A, Tanaka C, Kobayashi D, Fujiwara M, Iwata N, Hayashi M, Yamada S, Nakayama G, Fujii T, Sugimoto H, Koike M, Takami H, Niwa Y, Murotani K, Kodera Y

    Medicine   Vol. 95 ( 24 ) page: e3781   2016.6

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1097/MD.0000000000003781

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  162. Tumor Infiltrative Pattern Predicts Sites of Recurrence After Curative Gastrectomy for Stages 2 and 3 Gastric Cancer.

    Kanda M, Mizuno A, Fujii T, Shimoyama Y, Yamada S, Tanaka C, Kobayashi D, Koike M, Iwata N, Niwa Y, Hayashi M, Takami H, Nakayama G, Sugimoto H, Fujiwara M, Kodera Y

    Annals of surgical oncology   Vol. 23 ( 6 ) page: 1934-40   2016.6

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    DOI: 10.1245/s10434-016-5102-x

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  163. Metastatic pathway-specific transcriptome analysis identifies MFSD4 as a putative tumor suppressor and biomarker for hepatic metastasis in patients with gastric cancer.

    Kanda M, Shimizu D, Tanaka H, Shibata M, Iwata N, Hayashi M, Kobayashi D, Tanaka C, Yamada S, Fujii T, Nakayama G, Sugimoto H, Koike M, Fujiwara M, Kodera Y

    Oncotarget   Vol. 7 ( 12 ) page: 13667-79   2016.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.18632/oncotarget.7269

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  164. Short-term outcomes after conventional transthoracic esophagectomy.

    Niwa Y, Koike M, Hattori M, Iwata N, Takami H, Hayashi M, Kanda M, Kobayashi D, Tanaka C, Yamada S, Fujii T, Nakayama G, Sugimoto H, Nomoto S, Fujiwara M, Kodera Y

    Nagoya journal of medical science   Vol. 78 ( 1 ) page: 69-78   2016.2

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    PubMed

  165. The Prognostic Relevance of Subcarinal Lymph Node Dissection in Esophageal Squamous Cell Carcinoma.

    Niwa Y, Koike M, Hattori M, Iwata N, Takami H, Hayashi M, Tanaka C, Kobayashi D, Kanda M, Yamada S, Fujii T, Nakayama G, Sugimoto H, Fujiwara M, Kodera Y

    Annals of surgical oncology     2015.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1245/s10434-015-4819-2

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  166. CCNJ detected by triple combination array analysis as a tumor-related gene of hepatocellular carcinoma.

    Takano N, Hishida M, Inokawa Y, Hayashi M, Kanda M, Nishikawa Y, Iwata N, Kobayashi D, Tanaka C, Yamada S, Nakayama G, Fujii T, Sugimoto H, Koike M, Fujiwara M, Kodera Y, Nomoto S

    International journal of oncology   Vol. 46 ( 5 ) page: 1963-70   2015.5

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    DOI: 10.3892/ijo.2015.2892

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  167. Detection of doublecortin domain-containing 2 (DCDC2), a new candidate tumor suppressor gene of hepatocellular carcinoma, by triple combination array analysis.

    Inokawa Y, Nomoto S, Hishida M, Hayashi M, Kanda M, Nishikawa Y, Takeda S, Sugimoto H, Fujii T, Yamada S, Kodera Y

    Journal of experimental & clinical cancer research : CR   Vol. 32   page: 65   2013.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1186/1756-9966-32-65

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  168. Estrogen receptor 1 gene as a tumor suppressor gene in hepatocellular carcinoma detected by triple-combination array analysis.

    Hishida M, Nomoto S, Inokawa Y, Hayashi M, Kanda M, Okamura Y, Nishikawa Y, Tanaka C, Kobayashi D, Yamada S, Nakayama G, Fujii T, Sugimoto H, Koike M, Fujiwara M, Takeda S, Kodera Y

    International journal of oncology   Vol. 43 ( 1 ) page: 88-94   2013.7

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3892/ijo.2013.1951

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  169. Dynamin 3: a new candidate tumor suppressor gene in hepatocellular carcinoma detected by triple combination array analysis.

    Inokawa Y, Nomoto S, Hishida M, Hayashi M, Kanda M, Nishikawa Y, Takeda S, Fujiwara M, Koike M, Sugimoto H, Fujii T, Nakayama G, Yamada S, Tanaka C, Kobayashi D, Kodera Y

    OncoTargets and therapy   Vol. 6   page: 1417-24   2013

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.2147/OTT.S51913

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  170. Preservation of the pyloric ring has little value in surgery for pancreatic head cancer: a comparative study comparing three surgical procedures.

    Fujii T, Kanda M, Kodera Y, Nagai S, Sahin TT, Hayashi M, Kanzaki A, Yamada S, Sugimoto H, Nomoto S, Takeda S, Morita S, Nakao A

    Annals of surgical oncology   Vol. 19 ( 1 ) page: 176-83   2012.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1245/s10434-011-1901-2

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  171. Identification of the bleomycin hydrolase gene as a methylated tumor suppressor gene in hepatocellular carcinoma using a novel triple-combination array method.

    Okamura Y, Nomoto S, Hayashi M, Hishida M, Nishikawa Y, Yamada S, Fujii T, Sugimoto H, Takeda S, Kodera Y, Nakao A

    Cancer letters   Vol. 312 ( 2 ) page: 150-7   2011.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.canlet.2011.07.028

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  172. Pattern of lymph node metastasis spread in pancreatic cancer.

    Kanda M, Fujii T, Nagai S, Kodera Y, Kanzaki A, Sahin TT, Hayashi M, Yamada S, Sugimoto H, Nomoto S, Takeda S, Morita S, Nakao A

    Pancreas   Vol. 40 ( 6 ) page: 951-5   2011.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1097/MPA.0b013e3182148342

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  173. Promoter hypermethylation of fibulin 1 gene is associated with tumor progression in hepatocellular carcinoma.

    Kanda M, Nomoto S, Okamura Y, Hayashi M, Hishida M, Fujii T, Nishikawa Y, Sugimoto H, Takeda S, Nakao A

    Molecular carcinogenesis   Vol. 50 ( 8 ) page: 571-9   2011.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/mc.20735

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  174. Recurrence pattern and prognosis of pancreatic cancer after pancreatic fistula.

    Nagai S, Fujii T, Kodera Y, Kanda M, Sahin TT, Kanzaki A, Hayashi M, Sugimoto H, Nomoto S, Takeda S, Morita S, Nakao A

    Annals of surgical oncology   Vol. 18 ( 8 ) page: 2329-37   2011.8

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    DOI: 10.1245/s10434-011-1604-8

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  175. Reduced expression of reelin (RELN) gene is associated with high recurrence rate of hepatocellular carcinoma.

    Okamura Y, Nomoto S, Kanda M, Hayashi M, Nishikawa Y, Fujii T, Sugimoto H, Takeda S, Nakao A

    Annals of surgical oncology   Vol. 18 ( 2 ) page: 572-9   2011.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1245/s10434-010-1273-z

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Presentations 20

  1. Molecular surgical margin analysis and postoperative locoregional cancer recurrences International conference

    Masamichi Hayashi

    Molecular Biomarkers 2016 

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    Event date: 2016.9

    Language:English   Presentation type:Oral presentation (general)  

    Country:Germany  

  2. Multiple biomarker combination increased both versatility and recurrence-predictive accuracy of molecular deep surgical margin in head and neck squamous cell carcinoma International conference

    Hayashi Masamichi, Wayne M. Koch, Yasuhiro Kodera

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    Event date: 2016.4

    Language:English   Presentation type:Poster presentation  

    Country:United States  

  3. Epigenetic inactivation of VGF in urothelial cell carcinoma and its potential as a non-invasive biomarker

    Masamichi Hayashi, Mohammad Hoque, Yasuhiro Kodera(Johns Hopkins, Nagoya)

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    Event date: 2015.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  4. Engulfment gene GULP1 is a functional tumor suppressor through influencing TGF-β pathway and is silenced by promoter methylation in urothelial carcinoma International conference

    Masamichi Hayashi1, Leonardo O. Reis, Alexander Baras, Leonel Maldonado, Eliza Guida, Mariana Brait, Trinity Bivalacqua, George J Netto, Wayne Koch, David Sidransky, Mohammad O. Hoque(Johns Hopkins University)

    AACR Annual Meeting 2015 (American Association for Cancer Research) 

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    Event date: 2015.4

    Language:English   Presentation type:Poster presentation  

    Country:United States  

  5. Prognostic significance of miR-23b and miR-31 expression in non-small-cell lung cancer International conference

    Begum Shahnaz, Masamichi Hayashi, Takenori Ogawa, Mariana Brait, William H. Westra, Mohammad O. Hoque, David Sidransky (Johns Hopkins University)

    AACR Annual Meeting 2014 (American Association for Cancer Research) 

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    Event date: 2014.4

    Language:English   Presentation type:Poster presentation  

    Country:United States  

  6. Innovative rapid gene methylation analysis of surgical margin tissues in head and neck cancer International conference

    Masamichi Hayashi, Rafael Guerrero-Preston, Zubair Kahn, Xiufeng Li, Julie Ahn, Marla Goldsmith, Christina Michailidi, Wayne Koch(Johns Hopkins University)

    AACR Annual Meeting 2014 (American Association for Cancer Research) 

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    Event date: 2014.4

    Language:English   Presentation type:Poster presentation  

    Country:United States  

  7. Epigenetic inactivation of VGF in urothelial cell carcinoma and its potential as a non-invasive biomarker using urine International conference

    Masamichi Hayashi, Heike Bernert, Luciane Tsukamoto Kagohara, Mariana Brait, Mark Schoenberg, Trinity Bivalacqua, George Netto, Wayne Koch, David Sidransky, Mohammad O. Hoque(Johns Hopkins University)

    AACR Annual Meeting 2014 (American Association for Cancer Research) 

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    Event date: 2014.4

    Language:English   Presentation type:Poster presentation  

    Country:United States  

  8. Mutational heterogeneity related to neoadjuvant therapy response in muscle invasive urothelial cell carcinoma revealed by whole-exome sequencing International conference

    Masamichi Hayashi, Enrico Munari, Christina Michailidi, Mariana Brait, Mark Schoenberg, Trinity Bivalacqua, George Netto, Wayne Koch, David Sidransky, Mohammad O.Hoque(Johns Hopkins University)

    AACR Annual Meeting 2014 (American Association for Cancer Research) 

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    Event date: 2014.4

    Language:English   Presentation type:Poster presentation  

    Country:United States  

  9. Correlation of methylation status of deep surgical margins with the local reccurence of head and neck squamous cell carcinoma. International conference

    Masamichi Hayashi, Gaosong Wu, Xiaofei Chang, Xiufeng Li, Julie Ahn, Zubair Khan, Belinda Akpeng, Jong-Lyel Roh, Wayne Koch (The Johns Hopkins University)

    AACR (American Association for Cancer Research) Annual Meeting 2013 

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    Event date: 2013.4

    Language:English   Presentation type:Poster presentation  

    Country:United States  

  10. 肝細胞癌におけるトリプルアレイ法による癌関連遺伝子の検索 〜COL1A1遺伝子の解析〜

    林真路,野本周嗣,菱田光洋,猪川祥邦,山田豪,藤井努,杉本博行,竹田伸,小寺泰弘

    第112回日本外科学会定期学術集会 

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    Event date: 2012.4

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  11. 膵頭十二指腸切除術における減黄処置への功罪〜特に胆汁内瘻と外瘻の比較〜

    林真路,藤井努,山村和生,岡村行泰,長井俊志,神田光郎,神崎章之,山田豪.杉本博行,野本周嗣,小寺泰弘,竹田伸,中尾昭公* (名古屋セントラル病院*)

    第73回日本臨床外科学会総会 

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    Event date: 2011.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京   Country:Japan  

  12. 膵癌に対する膵頭十二指腸切除術における術後SSI発生関連因子の検討と対策

    林真路,藤井努,神崎章之,山村和生,山田豪.杉本博行,野本周嗣,小寺泰弘,竹田伸,中尾昭公

    第66回日本消化器外科学会総会 

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    Event date: 2011.7

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:名古屋   Country:Japan  

  13. 膵癌に対する膵頭十二指腸切除術における術前減黄処置の周術期への影響

    林真路,藤井努,山村和生,山田豪.杉本博行,野本周嗣,小寺泰弘,竹田伸,中尾昭公

    第23回日本肝胆膵外科学会・学術集会 

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    Event date: 2011.6

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:東京   Country:Japan  

  14. Triple array法により同定したcollagen type1 alpha1(以下COL1A1)遺伝子の肝細胞癌における発現の検討

    林真路,野本周嗣,岡村行泰,菱田光洋,藤井努,杉本博行,竹田伸,中尾昭公

    第111回日本外科学会定期学術集会 

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    Event date: 2011.5

    Language:Japanese   Presentation type:Poster presentation  

    Venue:紙上開催   Country:Japan  

  15. Triple combination array analysis detects the Collagen type1 alpha1 (COL1A1) gene as a new tumor related gene in hepatocellular carcinoma. International conference

    Hayashi Masamichi, Shuji Nomoto, Yukiyasu Okamura, Mitsuhiro Hishida, Yoko Nishikawa, Tsutomu Fujii, Hiroyuki Sugimoto, Shin Takeda, Akimasa Nakao

    AACR 102nd Annual Meeting 

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    Event date: 2011.4

    Language:English   Presentation type:Poster presentation  

    Country:United States  

  16. 術後遠隔成績からみた膵IPMNの手術適応~再発症例の解析~

    林真路,藤井努,山田豪,神崎章之,杉本博行,野本周嗣,小寺泰弘,竹田伸,中尾昭公

    第65回日本消化器外科学会総会 

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    Event date: 2010.7

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:下関   Country:Japan  

  17. Eleven cases of resection pancreatic metastases.(膵転移癌切除の11症例)

    Joint Meeting of the International Association of Pancreatology and the Japan Pancreas Society 2010(第14回国際膵臓学会・第41回日本膵臓学会大会合同会議) 

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    Event date: 2010.7

    Language:English   Presentation type:Poster presentation  

    Venue:福岡   Country:Japan  

  18. 肝MALTリンパ腫の1例

    林真路,竹田伸,岡村行泰,藤井努,杉本博行,野本周嗣,中尾昭公

    第279回東海外科学会 

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    Event date: 2010.4

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:名古屋   Country:Japan  

  19. Double combination array analysis detected A kinase anchor protein 12 (AKAP12) gene as a new tumor suppressor gene of hepatocellular carcinoma. International conference

    Masamichi Hayashi, Shuji Nomoto, Mitsuro Kanda, Yukiyasu Okamura, Tsutomu Fujii, Hiroyuki Sugimoto, Shin Takeda, Akimasa Nakao

    AACR American Association for Cancer Research 101st Annual Meeting 2010 

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    Event date: 2010.4

    Language:English   Presentation type:Poster presentation  

    Country:United States  

  20. 肝細胞癌におけるA kinase anchor protein 12 (AKAP12) 遺伝子の発現について

    林真路,野本周嗣,岡村行泰,神田光郎,藤井努,杉本博行,竹田伸,中尾昭公

    第110回日本外科学会定期学術集会 

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    Event date: 2010.4

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:名古屋   Country:Japan  

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Research Project for Joint Research, Competitive Funding, etc. 4

  1. Molecular surgical margin analysis of pancreatic cancers

    2018.2 - 2018.4

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    Grant type:Competitive

  2. 肝細胞癌治療における集学的治療戦略オプションとしてのナノドラッグ治療

    2016.9 - 2017.6

    公益信託外科学研究助成基金 

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    Grant type:Competitive

  3. 多血管性腫瘍におけるEGFR親和性新規Drug delivery systemの抗腫瘍効果の検討

    2016.4 - 2017.3

    愛知県がん研究振興会 

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    Grant type:Competitive

  4. 肝癌における新規ナノドラッグデリバリーシステムの構築

    2016.4 - 2017.3

    工藤学術財団 

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    Grant type:Competitive

KAKENHI (Grants-in-Aid for Scientific Research) 8

  1. one carbon metabolismによる膵癌制御の可能性

    Grant number:21K07147   2021.4 - 2024.3

    基盤研究(C)

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    Authorship:Principal investigator 

  2. 膵癌進展を反映する尿中メチル化セルフリーDNAの臨床応用

    Grant number:19K18143  2019.4 - 2022.3

  3. Margin imprint法による外科的切除断端の分子生物学的解析

    Grant number:15H06281  2015.4 - 2017.3

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    Authorship:Principal investigator 

  4. 消化器外科手術切除断端へのRapid QMSP法の応用

    Grant number:15K19850  2015.4 - 2017.3

  5. 膵癌腹膜播種に対する新規バイオマーカー: 臨床応用に向けた検証と新規治療法開発

    Grant number:21K07188  2021.4 - 2025.3

    末永 雅也, 林 真路, 高見 秀樹, 猪川 祥邦

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    Authorship:Coinvestigator(s) 

    膵癌の腹膜播種は予後を規定する重要な因子である。近年、膵癌手術患者の腹腔腔洗浄液
    中から高感度測定法を用いて検出される腫瘍DNAが腹膜播種の有望なバイオマーカーとなる可能性を報告した。本研究ではこの手法の臨床応用を目的として、前向き臨床試験によって有用性を検証する。さらに、本研究で得られた腹腔洗浄液を用いて、将来的な治療ターゲットに応用可能な新規バイオマーカーの探索する。

  6. 腫瘍由来エクソソームによる膵癌マルチオミクス・プロファイリングの挑戦と臨床応用

    Grant number:19K09214  2019.4 - 2022.3

    山田 豪

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    Authorship:Coinvestigator(s) 

    本研究では初発再発形式ごとに血液検体からエクソソームを抽出し、トランスクリプトーム解析および、プロテオミクス解析による「エクソソーム・マルチオミクス解析」を行う。次に、サブタイプ分類確立の礎となるEpithelial to mesenchymal transition (EMT) statusを判別する「EMTマルチオミクス・パネル」を開発する。さらに、膵癌組織検体と血液においてEMTマルチオミクス・パネルを解析し、膵癌の再発・進展形式を鋭敏に予測しうる癌細胞由来エクソソームの遺伝子・分子群を絞り込む。最終的には、生物統計学的処理により「膵癌マルチオミクス・プロファイル」の新たな開発をめざす。
    本研究では膵癌が局所進展タイプと遠隔転移タイプに大別され、細胞分子学的にこれらの同定が可能となるような差異を見出すことを目的としている。術前に組織採取が比較的困難な膵癌の特性を考慮し、リキッドバイオプシーとして有望な血液中のエクソソームを研究対象とした。これまで膵癌を含む膵疾患患者の血液からエクソソームを抽出可能であることは電子顕微鏡およびNanostreamで確認した。当科で手術を含む集学的治療を予定された膵癌患者のうち、初発再発部位が肝(n=8)、肺(n=1)、腹膜(n=1)、局所(n=5)および、無再発(n=5)の20症例の血液検体を用いた。血中に含まれるエクソソームを抽出し、さらにエクソソームに含まれるtotal RNAを抽出した上でBGISEQ-500によるhigh throughput sequencingを行った。得られた網羅的miRNA-seq情報を解析したところ遠隔タイプ、局所タイプ、および無再発例の間で有意に発現が異なり、バイオマーカーとして有望と考えられるmiRNAは認めなかった。また、上記網羅的miRNA解析に用いた20例中の10例についてメタボロミクス解析を検討した。今回はエクソソーム中の脂質代謝物であるリピドームについて網羅的解析を行った。この結果、エーテル化ホスファチジルコリンのクラスが無再発例で肝転移、局所転移のグループと比較してエクソソーム内の含有が低いことが明らかとなった。今後はhigh throughput sequencingによる血液エクソソーム中のmRNA解析およびメタボロミクスとしてのリピドーム解析を進め、最終的にはマルチオミクス解析として統合したデータを得る予定である。
    マルチオミクスのうち、miRNAとリピドームについては解析可能であったが、mRNA等、他の分子については検体量の問題から今回用いた症例では追加解析が不可能であった。現在前向きにも症例は蓄積中のため、充分量の血液検体が得られた症例で詳細な予後情報が利用可能なものについてさらにmRNA-seqやメタボロミクス、リピドミクスなどの網羅的解析を行う予定である。
    前向きに蓄積をすすめている膵疾患の血液検体について、マルチオミクス解析を行うのに充分な血液量および、詳細な臨床病理学的情報および予後情報が利用可能なものについてmRNA-seq、メタボロミクスおよびリピドミクス等の網羅的解析を進める。

  7. Molecule target for treatment and companion diagnostic tool of peritoneal dissemination in gastric cancer

    Grant number:17H04281  2017.4 - 2020.3

    KODERA Yasuhiro

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    Authorship:Coinvestigator(s) 

    Peritoneal metastasis is a frequent cause of death in patients with gastric cancer. The pathophysiology and thus targets for treatment are unknown. Synaptotagmin XIII (SYT13) was expressed in patients with peritoneal recurrence of gastric cancer. Inhibition of SYT13 expression in gastric cancer cell lines was associated with decreased invasion and migration ability of the cells. In vivo experiments using a mouse xenograft model of gastric cancer showed that intraperitoneal administration of SYT13-specific small interfering RNA or antibodies significantly inhibited the growth of peritoneal nodules and prolonged survival. SYT13 expression in primary gastric cancer tissues or ascites fluids had diagnostic potential both in the detection and prediction of peritoneal metastasis of gastric cancer. SYT13 may also be a promising target for the treatment of peritoneal metastasis of gastric cancer.

  8. The diagnostic performance and mechanisms of the release into the circulation of novel serum biomarkers for gastric cancer

    Grant number:17K10581  2017.4 - 2020.3

    KANDA Mitsuro

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    Authorship:Coinvestigator(s) 

    Development of high-performance serum biomarkers will likely improve treatment outcomes of patients with gastric cancer (GC). We conducted a prospective multicenter observational study aimed at validating the diagnostic performance of these potential markers. We analyzed serum levels before and after surgery of the three potential biomarkers in patients with GC and healthy volunteers. Quantification of serum and GC tissue levels was performed using an ELISA. Area under the curve values that discriminated patients with GC from healthy controls were-0.7058, 0.6188, and 0.5031 for ANOS1, DPYSL3, and MAGED2, respectively. Serum ANOS1 levels were significantly elevated in patients with stage I GC compared with those of healthy controls and decreased after resection of primary GC lesions. The combination of serum ANOS1 and DPYSL3 levels increased the AUC value that discriminated patients with GC from healthy controls.

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