研究者詳細 - 大岡　史治

論文 - 大岡　史治

分割表示 >> ／全件表示 87 件中 1 - 87 件目

Molecular insights and the role of 18F-FDG-PET/CT in the diagnosis of spinal gliomas.

Nagashima Y, Nishimura Y, Eguchi K, Yamaguchi J, Haimoto S, Ohka F, Motomura K, Abe T, Matsuo M, Tsukamoto E, Hara M, Saito R

Acta neurochirurgica 166 巻 ( 1 ) 頁： 154 2024年3月

Awake Craniotomy for Gliomas in the Non-Dominant Right Hemisphere: A Comprehensive Review

Mamadaliev, DM; Saito, R; Motomura, K; Ohka, F; Scalia, G; Umana, GE; Conti, A; Chaurasia, B

CANCERS 16 巻 ( 6 ) 2024年3月

Endoscopic debulking canalization for optic pathway glioma with obstructive hydrocephalus

Takeuchi, K; Ohka, F; Nagata, Y; Ito, E; Harada, H; Saito, R

CHILDS NERVOUS SYSTEM 39 巻 ( 12 ) 頁： 3421 - 3425 2023年12月

Fifteen-Fraction Radiosurgery Followed by Reduced-Dose Whole-Brain Irradiation With a Total Biologically Effective Dose of >90-100 Gy for a Locally Invasive Brain Metastasis From Lung Adenocarcinoma With a High Dissemination Potential

Ohtakara, K; Ohka, F; Tanahashi, K; Yamada, T; Suzuki, K

CUREUS JOURNAL OF MEDICAL SCIENCE 15 巻 ( 11 ) 頁： e49596 2023年11月

ESTABLISHMENT OF ORGANOID MODELS OF PATIENT-DERIVED GH-PRODUCING PITUITARY ADENOMA

Maeda, S; Ohka, F; Kanamori, F; Okumura, Y; Takeuchi, K; Nagata, Y; Motomura, K; Yamaguchi, J; Kibe, Y; Harada, H; Shimizu, H; Takido, Y; Saito, R

NEURO-ONCOLOGY 25 巻 2023年11月

INTRA-OPERATIVE ANALYSES OF GENETIC ALTERATIONS IN THE CENTRAL NERVOUS SYSTEM TUMORS USING RAPID QUANTITATIVE PCR DEVICE

Ohka, F; Maeda, S; Yamaguchi, J; Shimizu, H; Motomura, K; Takeuchi, K; Nagata, Y; Nishikawa, T; Kibe, Y; Takido, Y; Saito, R

NEURO-ONCOLOGY 25 巻 2023年11月

IMAGING FEATURES AND CONSIDERATION OF PROGRESSION PATTERN OF DIFFUSE HEMISPHERIC GLIOMAS, H3 G34-MUTANT

Kibe, Y; Ohka, F; Motomura, K; Aoki, K; Maeda, S; Yamaguchi, J; Shimizu, H; Saito, R

NEURO-ONCOLOGY 25 巻 2023年11月

GLIOBLASTOMA, IDH-WILDTYPE WITHOUT KEY MOLECULAR FEATURES

Saito, R; Motomura, K; Ohka, F; Yamaguchi, J; Maeda, S; Nishikawa, T; Mizutani, K; Kibe, Y; Shimizu, H; Takido, Y

NEURO-ONCOLOGY 25 巻 2023年11月

Development of machine learning models for predicting unfavorable functional outcomes from preoperative data in patients with chronic subdural hematomas

Fuse, Y; Nagashima, Y; Nishiwaki, H; Ohka, F; Muramatsu, Y; Araki, Y; Nishimura, Y; Ienaga, J; Nagatani, T; Seki, Y; Watanabe, K; Ohno, K; Saito, R

SCIENTIFIC REPORTS 13 巻 ( 1 ) 頁： 16997 2023年10月

Predictive factors of post-operative apathy in patients with diffuse frontal gliomas undergoing awake brain mapping

Motomura, K; Kawamura, A; Ohka, F; Aoki, K; Nishikawa, T; Yamaguchi, J; Kibe, Y; Shimizu, H; Maeda, S; Saito, R

JOURNAL OF NEUROPSYCHOLOGY 2023年9月

TUG1-mediated R-loop resolution at microsatellite loci as a prerequisite for cancer cell proliferation

Suzuki, MM; Iijima, K; Ogami, K; Shinjo, K; Murofushi, Y; Xie, JQ; Wang, XB; Kitano, Y; Mamiya, A; Kibe, Y; Nishimura, T; Ohka, F; Saito, R; Sato, S; Kobayashi, J; Yao, R; Miyata, K; Kataoka, K; Suzuki, HI; Kondo, Y

NATURE COMMUNICATIONS 14 巻 ( 1 ) 頁： 4521 2023年8月

Mutation detection of urinary cell-free DNA via catch-and-release isolation on nanowires for liquid biopsy

Takahashi, H; Yasui, T; Hirano, M; Shinjo, K; Miyazaki, Y; Shinoda, W; Hasegawa, T; Natsume, A; Kitano, Y; Ida, M; Zhang, M; Shimada, T; Paisrisarn, P; Zhu, ZT; Ohka, F; Aoki, K; Rahong, S; Nagashima, K; Yanagida, T; Baba, Y

BIOSENSORS & BIOELECTRONICS 234 巻頁： 115318 2023年8月

Latest classification of ependymoma in the molecular era and advances in its treatment: a review

Yamaguchi, J; Ohka, F; Motomura, K; Saito, R

JAPANESE JOURNAL OF CLINICAL ONCOLOGY 53 巻 ( 8 ) 頁： 653 - 663 2023年7月

Brain metastasis and intracranial leptomeningeal metastasis from malignant peripheral nerve sheath tumors: illustrative cases.

Ohno M, Haimoto S, Tsukushi S, Hosoda W, Ohka F, Saito R

Journal of neurosurgery. Case lessons 6 巻 ( 3 ) 2023年7月

Efficacy and safety of bevacizumab, irinotecan, and temozolomide combination for relapsed or refractory pediatric central nervous system embryonal tumor: a single-institution study

Shiba, Y; Motomura, K; Taniguchi, R; Kurimoto, M; Mizutani, K; Ohka, F; Aoki, K; Ito, E; Nishikawa, T; Yamaguchi, J; Kibe, Y; Shimizu, H; Maeda, S; Nakashima, T; Suzuki, H; Muramatsu, H; Takahashi, Y; Saito, R

JOURNAL OF NEUROSURGERY-PEDIATRICS 31 巻 ( 6 ) 頁： 624 - 632 2023年6月

Rapid detection of the MYD88 L265P mutation for pre- and intra-operative diagnosis of primary central nervous system lymphoma

Yamaguchi, J; Ohka, F; Kitano, Y; Maeda, S; Motomura, K; Aoki, K; Takeuchi, K; Nagata, Y; Hattori, H; Tsujiuchi, T; Motomura, A; Nishikawa, T; Kibe, Y; Shinjo, K; Kondo, Y; Saito, R

CANCER SCIENCE 114 巻 ( 6 ) 頁： 2544 - 2551 2023年6月

Clinical characteristics and radiological features of glioblastoma, IDH-wildtype, grade 4 with histologically lower-grade gliomas

Motomura, K; Kibe, Y; Ohka, F; Aoki, K; Yamaguchi, J; Saito, R

BRAIN TUMOR PATHOLOGY 40 巻 ( 2 ) 頁： 48 - 55 2023年4月

Easy-to-use machine learning system for the prediction of IDH mutation and 1p/19q codeletion using MRI images of adult-type diffuse gliomas

Nishikawa, T; Ohka, F; Aoki, K; Suzuki, H; Motomura, K; Yamaguchi, J; Maeda, S; Kibe, Y; Shimizu, H; Natsume, A; Innan, H; Saito, R

BRAIN TUMOR PATHOLOGY 40 巻 ( 2 ) 頁： 85 - 92 2023年4月

CD79B Y196 mutation is a potent predictive marker for favorable response to R-MPV in primary central nervous system lymphoma

Yamaguchi, J; Ohka, F; Lushun, C; Motomura, K; Aoki, K; Takeuchi, K; Nagata, Y; Ito, S; Mizutani, N; Ohno, M; Suzaki, N; Takasu, S; Seki, Y; Kano, T; Wakabayashi, K; Oyama, H; Kurahashi, S; Tanahashi, K; Hirano, M; Shimizu, H; Kitano, Y; Maeda, S; Yamazaki, S; Wakabayashi, T; Kondo, Y; Natsume, A; Saito, R

CANCER MEDICINE 12 巻 ( 6 ) 頁： 7116 - 7126 2023年3月

Identification of therapeutic targets exhibiting synthetic lethality with IDH1 inhibitor using the CRISPR/Cas9 system

Maeda, S; Aoki, K; Hinohara, K; Yamaguchi, J; Ohka, F; Natsume, A; Saito, R

CANCER SCIENCE 114 巻頁： 1460 - 1460 2023年2月

Intra-operative analysis of genetic alterations in brain tumor using rapid quantitative PCR device

Ohka, F; Maeda, S; Yamaguchi, J; Motomura, K; Saito, R

CANCER SCIENCE 114 巻頁： 1818 - 1818 2023年2月

All-in-One Nanowire Assay System for Capture and Analysis of Extracellular Vesicles from an ex Vivo Brain Tumor Model

Chattrairat, K; Yasui, T; Suzuki, S; Natsume, A; Nagashima, K; Iida, M; Zhang, M; Shimada, T; Kato, A; Aoki, K; Ohka, F; Yamazaki, S; Yanagida, T; Baba, Y

ACS NANO 17 巻 ( 3 ) 頁： 2235 - 2244 2023年1月

Imaging features of localized IDH wild-type histologically diffuse astrocytomas: a single-institution case series

Kibe, Y; Motomura, K; Ohka, F; Aoki, K; Shimizu, H; Yamaguchi, J; Nishikawa, T; Saito, R

SCIENTIFIC REPORTS 13 巻 ( 1 ) 頁： 23 2023年1月

CLINICAL AND MOLECULAR FEATURES OF GLIOBLASTOMA, IDH-WILDTYPE ARISING IN THE SETTING OF LI FRAUMENI SYNDROME

Kibe, Y; Ohka, F; Motomura, K; Aoki, K; Maeda, S; Yamaguchi, J; Nishikawa, T; Mizutani, K; Shimizu, H; Hiramatsu, T; Suzuki, K; Saito, R

NEURO-ONCOLOGY 24 巻頁： 154 - 154 2022年11月

ROLE OF CD79B Y196 MUTATION IN PCNSL AS A POTENT PREDICTIVE MARKER FOR FAVORABLE RESPONSE TO R-MPV TREATMENT AND DEVELOPMENT OF RAPID ALL-IN-ONE GENOTYPING SYSTEM FOR MOLECULAR MARKERS OF PCNSL

Yamaguchi, J; Ohka, F; Lushun, C; Motomura, K; Aoki, K; Takeuchi, K; Nagata, Y; Ito, S; Mizutani, N; Ohno, M; Suzaki, N; Takasu, S; Seki, Y; Tanahashi, K; Hirano, M; Shimizu, H; Kitano, Y; Maeda, S; Yamazaki, S; Wakabayashi, T; Kondo, Y; Saito, R

NEURO-ONCOLOGY 24 巻頁： 18 - 18 2022年11月

IDENTIFICATION OF A NOVEL THERAPEUTIC TARGET THAT IS SYNTHETICALLY LETHAL WITH MUTANT IDH INHIBITOR IN GLIOMA USING THE CRISPR/CAS9 GENOME EDITING TECHNOLOGY

Maeda, S; Aoki, K; Hinohara, K; Yamaguchi, J; Ohka, F; Motomura, K; Kibe, Y; Natsume, A; Saito, R

NEURO-ONCOLOGY 24 巻頁： 107 - 107 2022年11月

Endoscopic Trans-Mini-Cylinder Biopsy for Intraparenchymal Brain Lesions

Takeuchi, K; Ohka, F; Nagata, Y; Maeda, S; Tanahashi, K; Araki, Y; Yamamoto, T; Sasaki, H; Mizuno, A; Harada, H; Saito, R

WORLD NEUROSURGERY 167 巻頁： E1147 - E1153 2022年11月

Primary central nervous system malignant lymphoma in a patient with rheumatoid arthritis receiving tocilizumab: illustrative case.

Ohno M, Kuramitsu S, Iwakoshi A, Yamaguchi J, Ohka F, Saito R

Journal of neurosurgery. Case lessons 4 巻 ( 6 ) 2022年8月

Direct intracranial invasion of eccrine spiradenocarcinoma of the scalp: a case report and literature review

Kibe, Y; Tanahashi, K; Ohtakara, K; Okumura, Y; Ohka, F; Takeuchi, K; Nagata, Y; Motomura, K; Akahori, S; Mizuno, A; Sasaki, H; Shimizu, H; Yamaguchi, J; Nishikawa, T; Yokota, K; Saito, R

BMC NEUROLOGY 22 巻 ( 1 ) 頁： 223 2022年6月

Recent Molecular and Genetic Findings in Intramedullary Spinal Cord Tumors

Nagashima, Y; Nishimura, Y; Eguchi, K; Yamaguchi, J; Haimoto, S; Ohka, F; Takayasu, M; Saito, R

NEUROSPINE 19 巻 ( 2 ) 頁： 262 - 271 2022年6月

Supratotal Resection of Gliomas With Awake Brain Mapping: Maximal Tumor Resection Preserving Motor, Language, and Neurocognitive Functions

Motomura, K; Ohka, F; Aoki, K; Saito, R

FRONTIERS IN NEUROLOGY 13 巻頁： 874826 2022年5月

Increased Risk of Thyroid Dysfunction by PD-1 and CTLA-4 Blockade in Patients Without Thyroid Autoantibodies at Baseline

Iwama, S; Kobayashi, T; Yasuda, Y; Okuji, T; Ito, M; Ando, M; Zhou, X; Yamagami, A; Onoue, T; Kawaguchi, Y; Miyata, T; Sugiyama, M; Takagi, H; Hagiwara, D; Suga, H; Banno, R; Hase, T; Morise, M; Wakahara, K; Yokota, K; Kato, M; Nishio, N; Tanaka, C; Miyata, K; Ogura, A; Ito, T; Sawada, T; Shimokata, T; Niimi, K; Ohka, F; Ishigami, M; Gotoh, M; Hashimoto, N; Saito, R; Kiyoi, H; Kajiyama, H; Ando, Y; Hibi, H; Sone, M; Akiyama, M; Kodera, Y; Arima, H

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 107 巻 ( 4 ) 頁： E1620 - E1630 2022年3月

Reliability of IDH1-R132H and ATRX and/or p53 immunohistochemistry for molecular subclassification of Grade 2/3 gliomas

Nishikawa, T; Watanabe, R; Kitano, Y; Yamamichi, A; Motomura, K; Ohka, F; Aoki, K; Hirano, M; Kato, A; Yamaguchi, J; Maeda, S; Kibe, Y; Saito, R; Wakabayashi, T; Kato, Y; Sato, S; Ogino, T; Natsume, A; Ito, I

BRAIN TUMOR PATHOLOGY 39 巻 ( 1 ) 頁： 14 - 24 2022年1月

(11)C-methionine- and (18)F-FDG-PET double-negative metastatic brain tumor from lung adenocarcinoma with paradoxical high (18)F-FDG uptake: A case report.

Tanahashi K, Hirano M, Chalise L, Tsugawa T, Okumura Y, Hase T, Ohka F, Motomura K, Takeuchi K, Nagata Y, Nakahara N, Hashimoto N, Saito R

Surgical neurology international 13 巻頁： 372 2022年

Dural Arteriovenous Fistula Mimicking a Brain Tumor on Methionine-positron Emission Tomography: A Case Report.

Hanyu T, Nishihori M, Izumi T, Motomura K, Ohka F, Goto S, Araki Y, Yokoyama K, Uda K, Saito R

NMC case report journal 9 巻頁： 289 - 294 2022年

Newly established patient-derived organoid model of intracranial meningioma

Yamazaki, S; Ohka, F; Hirano, M; Shiraki, Y; Motomura, K; Tanahashi, K; Tsujiuchi, T; Motomura, A; Aoki, K; Shinjo, K; Murofushi, Y; Kitano, Y; Maeda, S; Kato, A; Shimizu, H; Yamaguchi, J; Adilijiang, A; Wakabayashi, T; Saito, R; Enomoto, A; Kondo, Y; Natsume, A

NEURO-ONCOLOGY 23 巻 ( 11 ) 頁： 1936 - 1948 2021年11月

Intraoperative seizure outcome of levetiracetam combined with perampanel therapy in patients with glioma undergoing awake brain surgery

Motomura, K; Chalise, L; Shimizu, H; Yamaguchi, J; Nishikawa, T; Ohka, F; Aoki, K; Tanahashi, K; Hirano, M; Wakabayashi, T; Natsume, A

JOURNAL OF NEUROSURGERY 135 巻 ( 4 ) 頁： 998 - 1007 2021年10月

Driver Genetic Mutations in Spinal Cord Gliomas Direct the Degree of Functional Impairment in Tumor-Associated Spinal Cord Injury

Nagashima, Y; Nishimura, Y; Ohka, F; Eguchi, K; Aoki, K; Ito, H; Nishii, T; Oyama, T; Hara, M; Kitano, Y; Masaki, H; Wakabayashi, T; Natsume, A

CELLS 10 巻 ( 10 ) 2021年10月

Mathematical Modeling and Mutational Analysis Reveal Optimal Therapy to Prevent Malignant Transformation in Grade II IDH-Mutant Gliomas

Aoki, K; Suzuki, H; Yamamoto, T; Yamamoto, KN; Maeda, S; Okuno, Y; Ranjit, M; Motomura, K; Ohka, F; Tanahashi, K; Hirano, M; Nishikawa, T; Shimizu, H; Kitano, Y; Yamaguchi, J; Yamazaki, S; Nakamura, H; Takahashi, M; Narita, Y; Nakada, M; Deguchi, S; Mizoguchi, M; Momii, Y; Muragaki, Y; Abe, T; Akimoto, J; Wakabayashi, T; Saito, R; Ogawa, S; Haeno, H; Natsume, A

CANCER RESEARCH 81 巻 ( 18 ) 頁： 4861 - 4873 2021年9月

Long-term survival in patients with primary intracranial germ cell tumors treated with surgery, platinum-based chemotherapy, and radiotherapy: a single-institution study

Shimizu, H; Motomura, K; Ohka, F; Aoki, K; Tanahashi, K; Hirano, M; Chalise, L; Nishikawa, T; Yamaguchi, J; Yoshida, J; Natsume, A; Wakabayashi, T

JOURNAL OF NEUROSURGERY 135 巻 ( 2 ) 頁： 449 - 457 2021年8月

Impact of the extent of resection on the survival of patients with grade II and III gliomas using awake brain mapping

Motomura, K; Chalise, L; Ohka, F; Aoki, K; Tanahashi, K; Hirano, M; Nishikawa, T; Yamaguchi, J; Shimizu, H; Wakabayashi, T; Saito, R

JOURNAL OF NEURO-ONCOLOGY 153 巻 ( 2 ) 頁： 361 - 372 2021年6月

Urinary MicroRNA-Based Diagnostic Model for Central Nervous System Tumors Using Nanowire Scaffolds

Kitano, Y; Aoki, K; Ohka, F; Yamazaki, S; Motomura, K; Tanahashi, K; Hirano, M; Naganawa, T; Iida, M; Shiraki, Y; Nishikawa, T; Shimizu, H; Yamaguchi, J; Maeda, S; Suzuki, H; Wakabayashi, T; Baba, Y; Yasui, T; Natsume, A

ACS APPLIED MATERIALS & INTERFACES 13 巻 ( 15 ) 頁： 17316 - 17329 2021年4月

Expression of programmed cell death ligand-1 by immune cells in the microenvironment is a favorable prognostic factor for primary diffuse large B-cell lymphoma of the central nervous system

Tsuyuki, Y; Ishikawa, E; Kohno, K; Shimada, K; Ohka, F; Suzuki, Y; Mabuchi, S; Satou, A; Takahara, T; Kato, S; Miyagi, S; Ozawa, H; Kawano, T; Takagi, Y; Hiraga, J; Wakabayashi, T; Nakamura, S

NEUROPATHOLOGY 41 巻 ( 2 ) 頁： 99 - 108 2021年4月

Trautmann-focused mastoidectomy for a simple, safe presigmoid approach: technical note

Tanahashi, K; Uda, K; Araki, Y; Takeuchi, K; Choo, J; Chalise, L; Motomura, K; Ohka, F; Wakabayashi, T; Natsume, A

JOURNAL OF NEUROSURGERY 134 巻 ( 3 ) 頁： 843 - 847 2021年3月

Neurod4 converts endogenous neural stem cells to neurons with synaptic formation after spinal cord injury

Fukuoka, T; Kato, A; Hirano, M; Ohka, F; Aoki, K; Awaya, T; Adilijiang, A; Sachi, M; Tanahashi, K; Yamaguchi, J; Motomura, K; Shimizu, H; Nagashima, Y; Ando, R; Wakabayashi, T; Lee-Liu, D; Larrain, J; Nishimura, Y; Natsume, A

ISCIENCE 24 巻 ( 2 ) 頁： 102074 2021年2月

Survival Benefit of Supratotal Resection in a Long-term Survivor of IDH-wildtype Glioblastoma: A Case Report and Literature Review.

Yamaguchi J, Motomura K, Ohka F, Aoki K, Tanahashi K, Hirano M, Chalise L, Nishikawa T, Shimizu H, Natsume A, Wakabayashi T, Saito R

NMC case report journal 8 巻 ( 1 ) 頁： 747 - 753 2021年

INFANTILE HEMISPHERIC BRAIN TUMOR WITH A GOPC-ROS1 FUSION GENE: A CASE REPORT

Taniguchi, R; Natsume, A; Kawashima, N; Tanioka, S; Muramatsu, H; Hamada, M; Ichikawa, D; Imaya, M; Narita, K; Kurimoto, M; Shiba, Y; Aoki, K; Ohka, F; Hirato, J; Wakabayashi, T; Takahashi, Y

NEURO-ONCOLOGY 22 巻頁： 377 - 377 2020年12月

Solitary fibrous tumor/hemangiopericytoma treated with temozolomide plus bevacizumab: a report of four cases and literature review

Maeda, O; Ohka, F; Maesawa, S; Matsuoka, A; Shimokata, T; Mitsuma, A; Urakawa, H; Nakamura, S; Shimoyamas, Y; Nakaguro, SM; Wakabayashi, T; Ando, Y

NAGOYA JOURNAL OF MEDICAL SCIENCE 82 巻 ( 4 ) 頁： 631 - 644 2020年11月

Neurocognitive and functional outcomes in patients with diffuse frontal lower-grade gliomas undergoing intraoperative awake brain mapping

Motomura, K; Chalise, L; Ohka, F; Aoki, K; Tanahashi, K; Hirano, M; Nishikawa, T; Yamaguchi, J; Shimizu, H; Wakabayashi, T; Natsume, A

JOURNAL OF NEUROSURGERY 132 巻 ( 6 ) 頁： 1683 - 1691 2020年6月

Steroid-responsive recurrent tumefactive demyelination with multiple petechial hemorrhages along non-displaced medullary veins

Tsuboi, T; Harada, Y; Suzuki, M; Ando, T; Atsuta, N; Ohka, F; Takeuchi, K; Taoka, T; Ohba, S; Nakaguro, M; Abe, M; Nakashima, I; Yoshida, M; Katsuno, M

CLINICAL NEUROLOGY AND NEUROSURGERY 193 巻頁： 105764 2020年6月

Genetic analysis in patients with newly diagnosed glioblastomas treated with interferon-beta plus temozolomide in comparison with temozolomide alone

Natsume, A; Aoki, K; Ohka, F; Maeda, S; Hirano, M; Adilijiang, A; Motomura, K; Sumi, M; Nishikawa, R; Narita, Y; Muragaki, Y; Maruyama, T; Ito, T; Beppu, T; Nakamura, H; Kayama, T; Sato, S; Nagane, M; Mishima, K; Nakasu, Y; Kurisu, K; Yamasaki, F; Sugiyama, K; Onishi, T; Iwadate, Y; Terasaki, M; Kobayashi, H; Matsumura, A; Ishikawa, E; Sasaki, H; Mukasa, A; Matsuo, T; Hirano, H; Kumabe, T; Shinoura, N; Hashimoto, N; Aoki, T; Asai, A; Abe, T; Yoshino, A; Arakawa, Y; Asano, K; Yoshimoto, K; Shibui, S; Okuno, Y; Wakabayashi, T

JOURNAL OF NEURO-ONCOLOGY 148 巻 ( 1 ) 頁： 17 - 27 2020年5月

H3F3A mutant allele specific imbalance in an aggressive subtype of diffuse midline glioma, H3 K27M-mutant

Maeda, S; Ohka, F; Okuno, Y; Aoki, K; Motomura, K; Takeuchi, K; Kusakari, H; Yanagisawa, N; Sato, S; Yamaguchi, J; Tanahashi, K; Hirano, M; Kato, A; Shimizu, H; Kitano, Y; Yamazaki, S; Yamashita, S; Takeshima, H; Shinjo, K; Kondo, Y; Wakabayashi, T; Natsume, A

ACTA NEUROPATHOLOGICA COMMUNICATIONS 8 巻 ( 1 ) 頁： 8 2020年2月

Multiple metastases to the bone and bone marrow from a 1p/19q-codeleted and IDH2-mutant anaplastic oligodendroglioma: a case report and literature review

Shimizu, H; Motomura, K; Ohka, F; Aoki, K; Tanahashi, K; Hirano, M; Chalise, L; Nishikawa, T; Yamaguchi, J; Wakabayashi, T; Natsume, A

NEURO-ONCOLOGY ADVANCES 2 巻 ( 1 ) 頁： vdaa101 2020年1月

MACHINE LEARNING TO DETECT GLIOMAS IN URINE-BASED LIQUID BIOPSY

Kitano, Y; Aoki, K; Yasui, T; Motomura, K; Ohka, F; Tanahashi, K; Hirano, M; Nishikawa, T; Shimizu, H; Yamaguchi, J; Maeda, S; Yamazaki, S; Wakabayashi, T; Natsume, A

NEURO-ONCOLOGY 21 巻頁： 151 - 151 2019年11月

Pathogenic Epigenetic Consequences of Genetic Alterations in IDH-Wild-Type Diffuse Astrocytic Gliomas

Ohka, F; Shinjo, K; Deguchi, S; Matsui, Y; Okuno, Y; Katsushima, K; Suzuki, M; Kato, A; Ogiso, N; Yamamichi, A; Aoki, K; Suzuki, H; Sato, S; Rayan, NA; Prabhakar, S; Göke, J; Shimamura, T; Maruyama, R; Takahashi, S; Suzumura, A; Kimura, H; Wakabayashi, T; Zong, H; Natsume, A; Kondo, Y

CANCER RESEARCH 79 巻 ( 19 ) 頁： 4814 - 4827 2019年10月

Spontaneous Tumor Regression of Intracranial Solitary Fibrous Tumor Originating From the Medulla Oblongata: A Case Report and Literature Review

Yamaguchi, J; Motomura, K; Ohka, F; Aoki, K; Tanahashi, K; Hirano, M; Nishikawa, T; Shimizu, H; Wakabayashi, T; Natsume, A

WORLD NEUROSURGERY 130 巻頁： 400 - 404 2019年10月

Next Generation Sequencing-Based Transcriptome Predicts Bevacizumab Efficacy in Combination with Temozolomide in Glioblastoma

Adilijiang, A; Hirano, M; Okuno, Y; Aoki, K; Ohka, F; Maeda, S; Tanahashi, K; Motomura, K; Shimizu, H; Yamaguchi, J; Wakabayashi, T; Natsume, A

MOLECULES 24 巻 ( 17 ) 2019年9月

Aberrant Active cis-Regulatory Elements Associated with Downregulation of RET Finger Protein Overcome Chemoresistance in Glioblastoma

Ranjit, M; Hirano, M; Aoki, K; Okuno, Y; Ohka, F; Yamamichi, A; Kato, A; Maeda, S; Motomura, K; Matsuo, K; Enomoto, A; Ino, Y; Todo, T; Takahashi, M; Wakabayashi, T; Kato, T; Natsume, A

CELL REPORTS 26 巻 ( 9 ) 頁： 2274 - + 2019年2月

Aberrant active-enhancers associated with downregulation of HDAC1-RFP complex overcome chemoresistance in glioblastoma

Hirano, M; Melissa, R; Ohka, F; Aoki, K; Yamamichi, A; Kato, T; Matsuo, K; Enomoto, A; Takahashi, M; Wakabayashi, T; Natsume, A

CANCER SCIENCE 109 巻頁： 207 - 207 2018年12月

Development of anticancer agents targeting long non-coding RNA

Katsushima, K; Natsume, A; Ohka, F; Shinjo, K; Shibata, T; Miyata, K; Kataoka, K; Kondo, Y

CANCER SCIENCE 109 巻頁： 352 - 352 2018年12月

ABERRANT ACTIVE-ENHANCERS ASSOCIATED WITH DOWNREGULATION OF HDAC1-RET FINGER PROTEIN COMPLEX OVERCOME CHEMORESISTANCE IN GLIOBLASTOMA

Hirano, M; Ranjit, M; Ohka, F; Aoki, K; Yamamichi, A; Kato, T; Matsuo, K; Enomoto, A; Takahashi, M; Wakabayashi, T; Natsume, A

NEURO-ONCOLOGY 20 巻頁： 111 - 111 2018年11月

Validation of a novel molecular RPA classification in glioblastoma (GBM-molRPA) treated with chemoradiation: A multi-institutional collaborative study

Wee, CW; Kim, IH; Park, CK; Kim, JW; Dho, YS; Ohka, F; Aoki, K; Motomura, K; Natsume, A; Kim, N; Suh, CO; Chang, JH; Kim, SH; Cho, WK; Lim, DH; Nam, DH; Choi, JW; Kim, IA; Kim, CY; Oh, YT; Cho, O; Chung, WK; Kim, SH; Kim, E

RADIOTHERAPY AND ONCOLOGY 129 巻 ( 2 ) 頁： 347 - 351 2018年11月

Supratotal Resection of Diffuse Frontal Lower Grade Gliomas with Awake Brain Mapping, Preserving Motor, Language, and Neurocognitive Functions

Motomura, K; Chalise, L; Ohka, F; Aoki, K; Tanahashi, K; Hirano, M; Nishikawa, T; Wakabayashi, T; Natsume, A

WORLD NEUROSURGERY 119 巻頁： 30 - 39 2018年11月

Characterization of lntraoperative Motor Evoked Potential Monitoring for Surgery of the Pediatric Population with Brain Tumors

Motomura, K; Sumita, K; Chalise, L; Nishikawa, T; Tanahashi, K; Ohka, F; Aoki, K; Hirano, M; Nakamura, T; Matsushita, T; Wakabayashi, T; Natsume, A

WORLD NEUROSURGERY 119 巻頁： E1052 - E1059 2018年11月

Neuroendoscopic Cylinder Surgery and 5-Aminolevulinic Acid Photodynamic Diagnosis of Deep-Seated Intracranial Lesions

Choo, J; Takeuchi, K; Nagata, Y; Ohka, F; Kishida, Y; Watanabe, T; Satoh, Y; Nagatani, T; Kato, K; Wakabayashi, T; Natsume, A

WORLD NEUROSURGERY 116 巻頁： E35 - E41 2018年8月

Immunohistochemical ATRX expression is not a surrogate for 1p19q codeletion

Yamamichi, A; Ohka, F; Aoki, K; Suzuki, H; Kato, A; Hirano, M; Motomura, K; Tanahashi, K; Chalise, L; Maeda, S; Wakabayashi, T; Kato, Y; Natsume, A

BRAIN TUMOR PATHOLOGY 35 巻 ( 2 ) 頁： 106 - 113 2018年4月

A novel high-sensitivity assay to detect a small fraction of mutant IDH1 using droplet digital PCR

Hirano, M; Ohka, F; Maeda, S; Chalise, L; Yamamichi, A; Aoki, K; Kato, A; Tanahashi, K; Motomura, K; Nishimura, Y; Hara, M; Shinjo, K; Kondo, Y; Wakabayashi, T; Natsume, A

BRAIN TUMOR PATHOLOGY 35 巻 ( 2 ) 頁： 97 - 105 2018年4月

Prognostic relevance of genetic alterations in diffuse lower-grade gliomas

Aoki, K; Nakamura, H; Suzuki, H; Matsuo, K; Kataoka, K; Shimamura, T; Motomura, K; Ohka, F; Shiina, S; Yamamoto, T; Nagata, Y; Yoshizato, T; Mizoguchi, M; Abe, T; Momii, Y; Muragaki, Y; Watanabe, R; Ito, I; Sanada, M; Yajima, H; Morita, N; Takeuchi, I; Miyano, S; Wakabayashi, T; Ogawa, S; Natsume, A

NEURO-ONCOLOGY 20 巻 ( 1 ) 頁： 66 - 77 2018年1月

Aberrant super-enhancers associated with downregulation of RET finger protein overcomes chemoresistance in glioblastoma

Hirano, M; Ranjit, M; Yamamichi, A; Aoki, K; Ohka, F; Kato, T; Enomoto, A; Takahashi, M; Wakabayashi, T; Natsume, A

CANCER SCIENCE 109 巻頁： 461 - 461 2018年1月

Targeting Dysregulation of EZH2-H3K27me3 as an Effective Treatment for IDH-wildtype Lower Grade Glioma

Ohka, F; Natsume, A; Suzuki, H; Aoki, K; Deguchi, S; Katsushima, K; Shinjo, K; Wakabayashi, T; Kondo, Y

CANCER SCIENCE 109 巻頁： 463 - 463 2018年1月

Does ATRX immunohistochemistry deserve a surrogate of 1p/19q codel in grade II, III gliomas?

Yamamichi, A; Ohka, F; Aoki, K; Suzuki, H; Hirano, M; Motomura, K; Wakabayashi, T; Kato, Y; Natsume, A

CANCER SCIENCE 109 巻頁： 926 - 926 2018年1月

Development of anticancer agents targeting long non-coding RNA TUG1

Katsushima, K; Natsume, A; Ohka, F; Deguchi, S; Shinjo, K; Shibata, T; Miyata, K; Kataoka, K; Kondo, Y

CANCER SCIENCE 109 巻頁： 398 - 398 2018年1月

Significance of perivascular tumour cells defined by CD109 expression in progression of glioma

Shiraki, Y; Mii, S; Enomoto, A; Momota, H; Han, YP; Kato, T; Ushida, K; Kato, A; Asai, N; Murakumo, Y; Aoki, K; Suzuki, H; Ohka, F; Wakabayashi, T; Todo, T; Ogawa, S; Natsume, A; Takahashi, M

JOURNAL OF PATHOLOGY 243 巻 ( 4 ) 頁： 468 - 480 2017年12月

Organotypic brain explant culture as a drug evaluation system for malignant brain tumors

Minami, N; Maeda, Y; Shibao, S; Arima, Y; Ohka, F; Kondo, Y; Maruyama, K; Kusuhara, M; Sasayama, T; Kohmura, E; Saya, H; Sampetrean, O

CANCER MEDICINE 6 巻 ( 11 ) 頁： 2635 - 2645 2017年11月

Negative impact of leukoaraiosis on the incidence of brain metastases in patients with lung cancer

Hayashi, N; Mitsuya, K; Nakasu, Y; Naito, T; Ohka, F; Takahashi, T

JOURNAL OF NEURO-ONCOLOGY 135 巻 ( 2 ) 頁： 299 - 306 2017年11月

Remote ischemic preconditioning protects human neural stem cells from oxidative stress

Motomura, A; Shimizu, M; Kato, A; Motomura, K; Yamamichi, A; Koyama, H; Ohka, F; Nishikawa, T; Nishimura, Y; Hara, M; Fukuda, T; Bando, Y; Nishimura, T; Wakabayashi, T; Natsume, A

APOPTOSIS 22 巻 ( 11 ) 頁： 1353 - 1361 2017年11月

ABERRANT SUPER-ENHANCERS ASSOCIATED WITH DOWNREGULATION OF RET FINGER PROTEIN OVERCOMES CHEMORESISTANCE IN GLIOBLASTOMA

Hirano, M; Ranjit, M; Yamamichi, A; Aoki, K; Ohka, F; Kato, T; Enomoto, A; Takahashi, M; Wakabayashi, T; Natsume, A

NEURO-ONCOLOGY 19 巻頁： 103 - 103 2017年11月

POLYION COMPLEX-MEDIATED INTRAVENOUS DELIVERY OF ANTISENSE OLIGONUCLEOTIDES AGAINST THE NOTCH-REGULATED NON-CODING RNA TUG1 IN GLIOMA

Natsume, A; Katsushima, K; Ohka, F; Shinjo, K; Miyata, K; Kataoka, K; Kondo, Y

NEURO-ONCOLOGY 19 巻頁： 265 - 265 2017年11月

IS ATRX IMMUNOCHEMISTRY USEFUL AS A SUBSTITUTE FOR ANALYSIS OF 1p/19q CODELETION IN GRADES II, III GLIOMAS?

Yamamichi, A; Ohka, F; Aoki, K; Suzuki, H; Hirano, M; Motomura, K; Wakabayashi, T; Kato, Y; Natsume, A

NEURO-ONCOLOGY 19 巻頁： 180 - 180 2017年11月

Comparing the Efficacy of DeVIC Therapy and High-dose Methotrexate Monotherapy with Whole-brain Radiation Therapy for Newly-diagnosed Primary Central Nervous System Lymphoma: A Single Institution Study

Chalise, L; Motomura, K; Ohka, F; Hirano, M; Hara, M; Nishimura, Y; Natsume, A; Wakabayashi, T

ANTICANCER RESEARCH 37 巻 ( 9 ) 頁： 5215 - 5223 2017年9月

Oncogenic effects of evolutionarily conserved noncoding RNA ECONEXIN on gliomagenesis

Deguchi, S; Katsushima, K; Hatanaka, A; Shinjo, K; Ohka, F; Wakabayashi, T; Zong, H; Natsume, A; Kondo, Y

ONCOGENE 36 巻 ( 32 ) 頁： 4629 - 4640 2017年8月

PHASE I TRIAL OF TEMOZOLOMIDE PLUS BEVACIZUMAB FOR NEWLY DIAGNOSED HIGH-GRADE GLIOMAS IN THE ELDERLY: INTERIM REPORT

Kono, M; Arakawa, Y; Mineharu, Y; Ohka, F; Kinoshita, M; Nakae, S; Miyashita, K; Iuchi, T; Hirose, Y; Natsume, A; Nakada, M; Sasaki, H

NEURO-ONCOLOGY 19 巻頁： 81 - 81 2017年5月

Significance of low mTORC1 activity in defining the characteristics of brain tumor stem cells

Han, YP; Enomoto, A; Shiraki, Y; Wang, SQ; Wang, XZ; Toyokuni, S; Asai, N; Ushida, K; Ara, H; Ohka, F; Wakabayashi, T; Ma, J; Natsume, A; Takahashi, M

NEURO-ONCOLOGY 19 巻 ( 5 ) 頁： 636 - 647 2017年5月

A novel all-in-one intraoperative genotyping system for IDH1-mutant glioma

Ohka, F; Yamamichi, A; Kurimoto, M; Motomura, K; Tanahashi, K; Suzuki, H; Aoki, K; Deguchi, S; Chalise, L; Hirano, M; Kato, A; Nishimura, Y; Hara, M; Kato, Y; Wakabayashi, T; Natsume, A

BRAIN TUMOR PATHOLOGY 34 巻 ( 2 ) 頁： 91 - 97 2017年4月

Quantitative metabolome analysis profiles activation of glutaminolysis in glioma with IDH1 mutation

Fumiharu Ohka, Maki Ito, Melissa Ranjit, Takeshi Senga, Ayako Motomura, Kazuya Motomura, Kaori Saito, Keiko Kato, Yukinari Kato, Toshihiko Wakabayashi, Tomoyoshi Soga, Atsushi Natsume

Tumor Biology 2014年3月

Current trends in targeted therapies for glioblastoma multiforme

Fumiharu Ohka, Atsushi Natsume, Toshihiko Wakabayashi

Neurology Research International 2012年3月

The Global DNA Methylation Surrogate LINE-1 Methylation Is Correlated with MGMT Promoter Methylation and Is a Better Prognostic Factor for Glioma 査読有り

Fumiharu Ohka, Atsushi Natsume, Kazuya Motomura, Yugo Kishida, Yutaka Kondo, Tatsuya Abe, Yoko Nakasu, Hiroki Namba, Kenji Wakai, Takashi Fukui, Hiroyuki Momota, Kenichiro Iwami, Sayano Kinjo, Maki Ito, Masazumi Fujii, Toshihiko Wakabayashi

PLoS ONE 2011年8月

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