Updated on 2024/03/19

写真a

 
MORIMOTO Ryota
 
Organization
Nagoya University Hospital Cardiology Assistant Professor
Graduate School
Graduate School of Medicine
Title
Assistant Professor

Degree 1

  1. 博士(医学) ( 2017.4   名古屋大学 ) 

Research Interests 3

  1. 腫瘍循環器学

  2. 心臓サルコイドーシス

  3. 重症心不全

Research History 3

  1. Nagoya University   Assistant Professor

    2020.4

  2. Nagoya University   Assistant professor of hospital

    2018.4 - 2020.3

  3. Nagoya University   Endowed chair assistant professor

    2015.4 - 2018.3

Education 1

  1. Yamaguchi University   Faculty of Medicine

    1997.4 - 2003.3

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    Country: Japan

Professional Memberships 6

  1. 日本心不全学会

  2. 日本心臓病学会

  3. 日本内科学会

  4. 日本循環器学会

  5. 日本生体医工学会   東海支部評議員

  6. 日本サルコイドーシス/肉芽腫性疾患学会   東海支部評議員

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Papers 104

  1. Prognostic value of resting cardiac power index depends on mean arterial pressure in dilated cardiomyopathy Reviewed

    Morimoto Ryota, Mizutani Takashi, Araki Takashi, Oishi Hideo, Kimura Yuki, Kazama Shingo, Shibata Naoki, Kuwayama Tasuku, Hiraiwa Hiroaki, Kondo Toru, Furusawa Kenji, Okumura Takahiro, Murohara Toyoaki

    ESC HEART FAILURE   Vol. 8 ( 4 ) page: 3206 - 3213   2021.8

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/ehf2.13446

    Web of Science

    PubMed

  2. Prognostic impact of immune-related adverse events on patients with and without cardiovascular disease: a retrospective review Reviewed

    Kazama Shingo, Morimoto Ryota, Kimura Yuki, Shibata Naoki, Ozaki Reina, Araki Takashi, Mizutani Takashi, Oishi Hideo, Arao Yoshihito, Kuwayama Tasuku, Hiraiwa Hiroaki, Kondo Toru, Furusawa Kenji, Shimokata Tomoya, Okumura Takahiro, Bando Yasuko K., Ando Yuichi, Murohara Toyoaki

    CARDIO-ONCOLOGY   Vol. 7 ( 1 ) page: 26   2021.7

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1186/s40959-021-00112-z

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    PubMed

  3. Myocardial Vasculitis Associated With the Immune Checkpoint Inhibitor Pembrolizumab. Reviewed

    Oishi H, Morimoto R, Shimoyama Y, Kuroda K, Urata T, Kondo T, Okumura T, Bando YK, Akiyama M, Murohara T

    JACC. Case reports   Vol. 2 ( 12 ) page: 1937 - 1941   2020.10

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jaccas.2020.07.028

    PubMed

  4. Efficacy of Pulmonary Artery Pulsatility Index as a Measure of Right Ventricular Dysfunction in Stable Phase of Dilated Cardiomyopathy Reviewed

    CIRCULATION JOURNAL   Vol. 84 ( 9 ) page: 1536 - +   2020.9

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    Authorship:Corresponding author   Language:English  

    DOI: 10.1253/circj.CJ-20-0279

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  5. The balance of CD8-positive T cells and PD-L1 expression in the myocardium predicts prognosis in lymphocytic fulminant myocarditis

    Hiraiwa, H; Morimoto, R; Tsuyuki, Y; Ushida, K; Ito, R; Kazama, S; Kimura, Y; Araki, T; Mizutani, T; Oishi, H; Kuwayama, T; Kondo, T; Okumura, T; Murohara, T

    CARDIOLOGY   Vol. 149 ( 1 ) page: 28 - 39   2024.2

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  6. Thymus alterations and susceptibility to immune checkpoint inhibitor myocarditis (vol 29, pg 3100, 2023)

    Fenioux, C; Abbar, B; Boussouar, S; Bretagne, M; Power, JR; Moslehi, JJ; Gougis, P; Amelin, D; Dechartres, A; Lehmann, LH; Courand, PY; Cautela, J; Alexandre, J; Procureur, A; Rozes, A; Leonard-Louis, S; Qin, J; Akhter, N; Aghel, N; Amidi, K; Anderson, E; Arangalage, D; Aras, M; Asnani, A; Baldassarre, LA; Barovila, R; Barroso, AS; Bottinor, W; Bouali, A; Cariou, E; Chang, WT; Cheng, RK; Crusz, SM; Deswal, A; Dietrich, PY; Dy, G; Docq, C; Ewer, S; Fernando, S; Flint, DL; Florido, R; Fukushima, S; Galli, E; Gaughan, E; Habib, M; Haydon, A; Heinzerling, L; Ben Zadok, OI; Issa, N; Karlstaedt, A; Kitagawa, K; Layoun, M; Laufer-Perl, M; Lenneman, C; Leong, D; Lesiuk, C; Levenson, J; Lopez-Fernandez, T; Liu, Y; Machado, K; Moliner, P; Morimoto, R; Obeid, M; Narezkina, A; Palaskas, N; Peretto, G; Piriou, N; Plana, JC; Rainer, PP; Robert-Halabi, M; Rocher, F; Rota, E; Roubille, F; Ruf, T; Sandhu, S; Sanjeev, F; Seki, N; Tajiri, K; Tamura, Y; Thuny, F; Tresorier, R; Turker, I; Warner, E; Zaha, V; Zhu, H; Cheynier, R; Muylder, BCD; Redheuil, A; Tubach, F; Cadranel, J; Milon, A; Ederhy, S; Similowski, T; Johnson, DB; Pizzo, I; Catalan, T; Benveniste, O; Hayek, SS; Allenbach, Y; Rosenzwajg, M; Dolladille, C; Salem, JE

    NATURE MEDICINE     2024.1

  7. Prospective Analysis of Immunosuppressive Therapy in Cardiac Sarcoidosis With Fluorodeoxyglucose Myocardial Accumulation The PRESTIGE Study

    Morimoto, R; Unno, K; Fujita, N; Sakuragi, Y; Nishimoto, T; Yamashita, M; Kuwayama, T; Hiraiwa, H; Kondo, T; Kuwatsuka, Y; Okumura, T; Ohshima, S; Takahashi, H; Ando, M; Ishii, H; Kato, K; Murohara, T

    JACC-CARDIOVASCULAR IMAGING   Vol. 17 ( 1 ) page: 45 - 58   2024.1

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  8. Role of Common Antihypertensives in the Growth of Abdominal Aortic Aneurysm at the Presurgical Stage.

    Mitsui T, Bando YK, Hirakawa A, Furusawa K, Morimoto R, Taguchi E, Kimura A, Kamiya H, Nishikimi N, Komori K, Nishigami K, Murohara T

    Circulation reports   Vol. 5 ( 11 ) page: 405 - 414   2023.11

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    Language:English  

    DOI: 10.1253/circrep.CR-23-0071

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  9. Cardiac sympathetic activity and relationship to cardiac events and left ventricular reverse remodeling in patients with non-ischemic dilated cardiomyopathy

    Mizutani, T; Morimoto, R; Isobe, S; Ito, R; Araki, T; Kimura, Y; Kazama, S; Oishi, H; Kuwayama, T; Hiraiwa, H; Kondo, T; Okumura, T; Murohara, T

    ANNALS OF NUCLEAR MEDICINE   Vol. 37 ( 8 ) page: 451 - 461   2023.8

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  10. Dilated cardiomyopathy with anti-mitochondrial M2 antibody: A case series.

    Kazama S, Kondo T, Ito R, Kimura Y, Kuwayama T, Hiraiwa H, Morimoto R, Okumura T, Murohara T

    Journal of cardiology cases   Vol. 28 ( 1 ) page: 11 - 15   2023.7

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    Language:English  

    DOI: 10.1016/j.jccase.2023.02.021

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  11. Contractile pericarditis-like hemodynamics in dilated-phase hypertrophic cardiomyopathy with giant atrium.

    Morimoto R, Ito R, Araki T, Mizutani T, Kimura Y, Kazama S, Oishi H, Kuwayama T, Sugiura Y, Hiraiwa H, Kondo T, Okumura T, Kobayashi K, Mutsuga M, Murohara T

    Journal of cardiology cases   Vol. 27 ( 5 ) page: 199 - 202   2023.5

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    Language:English  

    DOI: 10.1016/j.jccase.2023.01.005

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  12. Dynamic chest radiography as a novel minimally invasive hemodynamic imaging method in patients with heart failure

    Hiraiwa, H; Sakamoto, G; Ito, R; Koyama, Y; Kazama, S; Kimura, Y; Kondo, T; Morimoto, R; Okumura, T; Murohara, T

    EUROPEAN JOURNAL OF RADIOLOGY   Vol. 161   page: 110729   2023.4

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  13. Cardiac Rehabilitation in Severe Heart Failure Patients with Impella 5.0 Support via the Subclavian Artery Approach Prior to Left Ventricular Assist Device Implantation

    Shimizu, M; Hiraiwa, H; Tanaka, S; Tsuchikawa, Y; Ito, R; Kazama, S; Kimura, Y; Araki, T; Mizutani, T; Oishi, H; Kuwayama, T; Kondo, T; Morimoto, R; Okumura, T; Ito, H; Yoshizumi, T; Mutsuga, M; Usui, A; Murohara, T

    JOURNAL OF PERSONALIZED MEDICINE   Vol. 13 ( 4 )   2023.4

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  14. The potential of dynamic (99m)Tc-sestamibi cadmium zinc telluride-single-photon emission computed tomography camera assessing myocardial flow reserve in patients with heart failure with preserved ejection fraction.

    Yoshida S, Unno K, Nanasato M, Niimi T, Inukai K, Morisaki H, Hattori T, Hirose M, Hayashi T, Uchida N, Simoda M, Oishi H, Ando M, Hirayama K, Takenaka M, Maeda M, Yoshida R, Ogura Y, Suzuki H, Furusawa K, Morimoto R, Kato K, Isobe S, Yoshida Y, Murohara T

    European heart journal open   Vol. 3 ( 2 ) page: oead028   2023.3

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    Language:English  

    DOI: 10.1093/ehjopen/oead028

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  15. Increased risk of purge system malfunction after Impella 5.0 replacement: a case series

    Oishi, H; Morimoto, R; Ito, R; Kazama, S; Kimura, Y; Araki, T; Mizutani, T; Kuwayama, T; Hiraiwa, H; Kondo, T; Okumura, T; Mutsuga, M; Usui, A; Murohara, T

    JOURNAL OF ARTIFICIAL ORGANS   Vol. 26 ( 1 ) page: 79 - 83   2023.3

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  16. Impact of an improved driveline management for HeartMate II and HeartMate 3 left ventricular assist devices

    Mutsuga, M; Okumura, T; Morimoto, R; Kondo, T; Ito, H; Terazawa, S; Tokuda, Y; Narita, Y; Nishida, K; Murohara, T; Usui, A

    ARTIFICIAL ORGANS   Vol. 47 ( 2 ) page: 387 - 395   2023.2

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  17. Prognostic value of malnutrition evaluated using the Global Leadership Initiative on Malnutrition criteria and its association with psoas muscle volume in non-ischemic dilated cardiomyopathy

    Ito, R; Hiraiwa, H; Araki, T; Mizutani, T; Kazama, S; Kimura, Y; Oishi, H; Kuwayama, T; Kondo, T; Morimoto, R; Okumura, T; Murohara, T

    HEART AND VESSELS   Vol. 37 ( 12 ) page: 2002 - 2012   2022.12

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  18. Prognostic value of malnutrition evaluated using the Global Leadership Initiative on Malnutrition criteria and its association with psoas muscle volume in non-ischemic dilated cardiomyopathy (Jun, 10.1007/s00380-022-02113-z, 2022)

    Ito, R; Hiraiwa, H; Araki, T; Mizutani, T; Kazama, S; Kimura, Y; Oishi, H; Kuwayama, T; Kondo, T; Morimoto, R; Okumura, T; Murohara, T

    HEART AND VESSELS   Vol. 37 ( 12 ) page: 2013 - 2013   2022.12

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  19. Recurrent fulminant non-rheumatic streptococcal myocarditis proven by endomyocardial biopsy and autopsy.

    Hiraiwa H, Morimoto R, Ando R, Ito R, Araki T, Mizutani T, Kazama S, Kimura Y, Oishi H, Kuwayama T, Yamaguchi S, Kondo T, Okumura T, Enomoto A, Murohara T

    Journal of cardiology cases   Vol. 26 ( 1 ) page: 62 - 65   2022.7

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    Language:English  

    DOI: 10.1016/j.jccase.2022.02.004

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  20. A Case of Systemic Capillary Leak Syndrome With Severe Cardiac Dysfunction After mRNA Vaccination for COVID-19

    Araki, T; Morimoto, R; Ito, R; Mizutani, T; Kimura, Y; Kazama, S; Oishi, H; Kuwayama, T; Hiraiwa, H; Kondo, T; Okumura, T; Murohara, T

    CJC OPEN   Vol. 4 ( 7 ) page: 656 - 659   2022.7

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  21. Impact of an Improved Standardized Strategy and Individually Tailored Protocol for Heartmate II and Heartmate 3 Left Ventricular Assist Devices on the Incidence of Driveline Infections

    Mutsuga, M; Okumura, T; Morimoto, R; Kondo, T; Ito, H; Uchida, W; Terazawa, S; Tokuda, Y; Narita, Y; Murohara, T; Usui, A

    JOURNAL OF HEART AND LUNG TRANSPLANTATION   Vol. 41 ( 4 ) page: S489 - S489   2022.4

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  22. Bedside cannulation for veno-venous extracorporeal membrane oxygenation using portable X-ray system in a coronavirus disease patient. Reviewed

    Kondo T, Kuwayama T, Hiraiwa H, Kasugai D, Goto Y, Numaguchi A, Katsu T, Matsui T, Hashimoto N, Tanaka A, Morimoto R, Okumura T, Murohara T

    Journal of cardiology cases   Vol. 25 ( 3 ) page: 185 - 187   2022.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jccase.2021.09.008

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  23. Clinical value of the HATCH score for predicting adverse outcomes in patients with heart failure Reviewed

    Shibata Naoki, Kondo Toru, Morimoto Ryota, Kazama Shingo, Sawamura Akinori, Nishiyama Itsumure, Kato Toshiaki, Kuwayama Tasuku, Hiraiwa Hiroaki, Umemoto Norio, Asai Toru, Okumura Takahiro, Murohara Toyoaki

    HEART AND VESSELS     2022.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00380-022-02035-w

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  24. Biopsy-proven Fulminant Myocarditis Requiring Mechanical Circulatory Support Following COVID-19 mRNA Vaccination. Reviewed

    Kazama S, Okumura T, Kimura Y, Ito R, Araki T, Mizutani T, Oishi H, Kuwayama T, Hiraiwa H, Kondo T, Morimoto R, Saeki T, Murohara T

    CJC open     2022.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.cjco.2022.02.004

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  25. Relationship between spleen size and exercise tolerance in advanced heart failure patients with a left ventricular assist device Reviewed

    Hiraiwa Hiroaki, Okumura Takahiro, Sawamura Akinori, Araki Takashi, Mizutani Takashi, Kazama Shingo, Kimura Yuki, Shibata Naoki, Oishi Hideo, Kuwayama Tasuku, Kondo Toru, Furusawa Kenji, Morimoto Ryota, Adachi Takuji, Yamada Sumio, Mutsuga Masato, Usui Akihiko, Murohara Toyoaki

    BMC RESEARCH NOTES   Vol. 15 ( 1 ) page: 40   2022.2

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  26. Methods for confirming the safety of radiation therapy in patients with left ventricular assist device: a case of extranodal NK/T-cell lymphoma, nasal type Reviewed

    Oishi Hideo, Kondo Toru, Kawamura Mariko, Shimada Kazuyuki, Mutsuga Masato, Kurokawa Takashi, Kuwayama Tasuku, Hiraiwa Hiroaki, Morimoto Ryota, Okumura Takahiro, Nishida Tetsuya, Kiyoi Hitoshi, Naganawa Shinji, Usui Akihiko, Murohara Toyoaki

    JOURNAL OF ARTIFICIAL ORGANS     2022.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s10047-022-01312-9

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  27. Serum autotaxin as a novel prognostic marker in patients with non-ischaemic dilated cardiomyopathy Reviewed

    Araki Takashi, Okumura Takahiro, Hiraiwa Hiroaki, Mizutani Takashi, Kimura Yuki, Kazama Shingo, Shibata Naoki, Oishi Hideo, Kuwayama Tasuku, Kondo Toru, Morimoto Ryota, Takefuji Mikito, Murohara Toyoaki

    ESC HEART FAILURE     2022.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/ehf2.13817

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  28. Splenic size as an indicator of hemodynamics and prognosis in patients with heart failure

    Hiraiwa Hiroaki, Okumura Takahiro, Sawamura Akinori, Araki Takashi, Mizutani Takashi, Kazama Shingo, Kimura Yuki, Shibata Naoki, Oishi Hideo, Kuwayama Tasuku, Kondo Toru, Furusawa Kenji, Morimoto Ryota, Murohara Toyoaki

    HEART AND VESSELS     2022.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00380-022-02030-1

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  29. Clinical Effect of Pulmonary Artery Diameter/Ascending Aorta Diameter Ratio on Left Ventricular Reverse Remodeling in Patients With Dilated Cardiomyopathy. Reviewed

    Shibata N, Hiraiwa H, Kazama S, Kimura Y, Araki T, Mizutani T, Oishi H, Kuwayama T, Kondo T, Morimoto R, Okumura T, Murohara T

    Circulation journal : official journal of the Japanese Circulation Society     2022.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1253/circj.CJ-21-0786

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  30. Flexion limitation of the Impella 5.0 when implanted using the femoral approach in patients with small stature Reviewed

    Hiraiwa Hiroaki, Kimura Yuki, Morimoto Ryota, Ito Ryota, Araki Takashi, Mizutani Takashi, Kazama Shingo, Oishi Hideo, Kuwayama Tasuku, Kondo Toru, Furusawa Kenji, Okumura Takahiro, Mutsuga Masato, Usui Akihiko, Murohara Toyoaki

    JOURNAL OF ARTIFICIAL ORGANS     2022.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s10047-022-01311-w

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  31. Impella5.0 "ILIPELLA" Approach for a Fulminant Myocarditis Patient With a Small Peripheral Artery. Reviewed

    Mutsuga M, Banno H, Okumura T, Morimoto R, Kondo T, Kimura Y, Hiraiwa H, Murohara T, Usui A

    Heart, lung & circulation     2022.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.hlc.2021.12.007

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  32. Prognostic impact of transcardiac gradient of follistatin-like 1 reflecting hemodynamics in patients with dilated cardiomyopathy Reviewed

    Oishi Hideo, Okumura Takahiro, Ohashi Koji, Kimura Yuki, Kazama Shingo, Shibata Naoki, Arao Yoshihito, Kato Hiroo, Kuwayama Tasuku, Yamaguchi Shogo, Tatsumi Minako, Kondo Toru, Hiraiwa Hiroaki, Morimoto Ryota, Takefuji Mikito, Ouchi Noriyuki, Murohara Toyoaki

    JOURNAL OF CARDIOLOGY   Vol. 78 ( 6 ) page: 524 - 532   2021.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jjcc.2021.07.005

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  33. Comparison of Impella 5.0 and extracorporeal left ventricular assist device in patients with cardiogenic shock Reviewed

    Kondo Toru, Morimoto Ryota, Mutsuga Masato, Fujimoto Kazuro, Okumura Takahiro, Shibata Naoki, Kazama Shingo, Kimira Yuki, Oishi Hideo, Kuwayama Tasuku, Hiraiwa Hiroaki, Usui Akihiko, Murohara Toyoaki

    INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS   Vol. 44 ( 11 ) page: 846 - 853   2021.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1177/03913988211040530

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  34. Serum autotaxin level predicts future cardiac events in patients with dilated cardiomyopathy

    Araki, T; Okumura, T; Mizutani, T; Kimura, Y; Kazama, S; Shibata, N; Oishi, H; Kuwayama, T; Hiraiwa, H; Kondo, T; Morimoto, R; Takefuji, M; Murohara, T

    EUROPEAN HEART JOURNAL   Vol. 42   page: 1730 - 1730   2021.10

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  35. Clinical impact of pulmonary artery to aorta diameter ratio on left ventricular reverse remodeling in patients with dilated cardiomyopathy

    Shibata, N; Hiraiwa, H; Kazama, S; Kimura, Y; Araki, T; Mizutani, T; Oishi, H; Kuwayama, T; Kondo, T; Morimoto, R; Okumura, T; Murohara, T

    EUROPEAN HEART JOURNAL   Vol. 42   page: 757 - 757   2021.10

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  36. Clinical significance of spleen size in patients with heart failure

    Hiraiwa, H; Okumura, T; Sawamura, A; Kondo, T; Araki, T; Mizutani, T; Kazama, S; Kimura, Y; Shibata, N; Oishi, H; Kuwayama, T; Furusawa, K; Morimoto, R; Murohara, T

    EUROPEAN HEART JOURNAL   Vol. 42   page: 756 - 756   2021.10

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  37. Clinical impact of visually assessed right ventricular dysfunction in patients with septic shock Invited Reviewed

    Hiraiwa Hiroaki, Kasugai Daisuke, Ozaki Masayuki, Goto Yukari, Jingushi Naruhiro, Higashi Michiko, Nishida Kazuki, Kondo Toru, Furusawa Kenji, Morimoto Ryota, Okumura Takahiro, Matsuda Naoyuki, Matsui Shigeyuki, Murohara Toyoaki

    SCIENTIFIC REPORTS   Vol. 11 ( 1 ) page: 18823   2021.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41598-021-98397-8

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  38. Clinical impact of heart rate change in patients with acute heart failure in the early phase Invited Reviewed

    Kazama Shingo, Kondo Toru, Shibata Naoki, Hiraiwa Hiroaki, Nishiyama Itsumure, Kato Toshiaki, Sawamura Akinori, Kimura Yuki, Oishi Hideo, Kuwayama Tasuku, Morimoto Ryota, Okumura Takahiro, Shimizu Kiyokazu, Murohara Toyoaki

    ESC HEART FAILURE   Vol. 8 ( 4 ) page: 2982 - 2990   2021.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/ehf2.13388

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  39. Two cases of dilated cardiomyopathy with blood pressure-limited tolerability of cardioprotective agents improved by ivabradine. Reviewed

    Okumura T, Hiraiwa H, Araki T, Mizutani T, Kimura Y, Kazama S, Shibata N, Oishi H, Kuwayama T, Kondo T, Morimoto R, Murohara T

    Journal of cardiology cases   Vol. 23 ( 4 ) page: 149 - 153   2021.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jccase.2020.11.007

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  40. A clinical score for predicting left ventricular reverse remodelling in patients with dilated cardiomyopathy Reviewed

    Kimura Yuki, Okumura Takahiro, Morimoto Ryota, Kazama Shingo, Shibata Naoki, Oishi Hideo, Araki Takashi, Mizutani Takashi, Kuwayama Tasuku, Hiraiwa Hiroaki, Kondo Toru, Murohara Toyoaki

    ESC HEART FAILURE   Vol. 8 ( 2 ) page: 1359 - 1368   2021.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/ehf2.13216

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  41. Association between splenic volume and pulsatility index in patients with left ventricular assist devices Reviewed

    Hiraiwa Hiroaki, Okumura Takahiro, Sawamura Akinori, Kondo Toru, Kazama Shingo, Kimura Yuki, Shibata Naoki, Arao Yoshihito, Oishi Hideo, Kato Hiroo, Kuwayama Tasuku, Yamaguchi Shogo, Furusawa Kenji, Morimoto Ryota, Fujimoto Kazuro, Mutsuga Masato, Usui Akihiko, Murohara Toyoaki

    INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS   Vol. 44 ( 4 ) page: 282 - 287   2021.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1177/0391398820957019

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  42. Associations between hemodynamic parameters at rest and exercise capacity in patients with implantable left ventricular assist devices Reviewed

      Vol. 44 ( 3 ) page: 174 - 180   2021.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1177/0391398820949888

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  43. A case of heart failure complicated with double ventricular response triggered by beta blocker. Reviewed

    Kazama S, Kondo T, Suga K, Yanagisawa S, Morimoto R, Okumura T, Inden Y, Murohara T

    HeartRhythm case reports   Vol. 7 ( 3 ) page: 174 - 177   2021.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.hrcr.2020.12.004

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  44. Impact of predictive value of Fibrosis-4 index in patients hospitalized for acute heart failure Reviewed

    Shibata Naoki, Kondo Toru, Kazama Shingo, Kimura Yuki, Oishi Hideo, Arao Yoshihito, Kato Hiroo, Yamaguchi Shogo, Kuwayama Tasuku, Hiraiwa Hiroaki, Morimoto Ryota, Okumura Takahiro, Sumi Takuya, Sawamura Akinori, Shimizu Kiyokazu, Murohara Toyoaki

    INTERNATIONAL JOURNAL OF CARDIOLOGY   Vol. 324   page: 90 - 95   2021.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.ijcard.2020.09.056

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  45. Targeted disruption of hir1 alters the transcriptional expression pattern of putative lignocellulolytic genes in the white-rot fungus Pleurotus ostreatus.

    Wu H, Nakazawa T, Morimoto R, Shivani, Sakamoto M, Honda Y

    Fungal genetics and biology : FG & B   Vol. 147   page: 103507   2021.2

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    Language:English  

    DOI: 10.1016/j.fgb.2020.103507

    PubMed

  46. Predictors of residual mitral regurgitation after left ventricular assist device implantation Reviewed

    Kimura Yuki, Okumura Takahiro, Kazama Shingo, Shibata Naoki, Oishi Hideo, Arao Yoshihito, Kuwayama Tasuku, Kato Hiroo, Yamaguchi Shogo, Hiraiwa Hiroaki, Kondo Toru, Morimoto Ryota, Mutsuga Masato, Fujimoto Kazuro, Usui Akihiko, Murohara Toyoaki

    INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS   Vol. 44 ( 2 ) page: 101 - 109   2021.2

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  47. A case of reexpansion pulmonary edema and acute pulmonary thromboembolism associated with diffuse large B-cell lymphoma treated with venovenous extracorporeal membrane oxygenation.

    Kazama S, Hiraiwa H, Kimura Y, Ozaki R, Shibata N, Arao Y, Oishi H, Kato H, Kuwayama T, Yamaguchi S, Kondo T, Furusawa K, Morimoto R, Okumura T, Bando YK, Sato T, Shimada K, Kiyoi H, Nakamura G, Yasuda Y, Kasugai D, Ogawa H, Higashi M, Yamamoto T, Jingushi N, Ozaki M, Numaguchi A, Goto Y, Matsuda N, Murohara T

    Journal of cardiology cases   Vol. 23 ( 1 ) page: 53 - 56   2021.1

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    DOI: 10.1016/j.jccase.2020.08.013

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  48. High-output Heart Failure Caused by a Tumor-related Arteriovenous Fistula: A Case Report and Literature Review

    Tobe Akihiro, Tanaka Akihito, Yoshida Satoya, Kondo Toru, Morimoto Ryota, Furusawa Kenji, Okumura Takahiro, Bando Yasuko K., Ishii Hideki, Murohara Toyoaki

    INTERNAL MEDICINE   Vol. 60 ( 18 ) page: 2979 - 2984   2021

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  49. Highly Sensitive Determination of Amino Acids by LC-MS under Neutral Conditions.

    Morimoto R, Matsumoto T, Minote M, Yanagisawa M, Yamada R, Kuranaga T, Kakeya H

    Chemical & pharmaceutical bulletin   Vol. 69 ( 3 ) page: 265 - 270   2021

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    DOI: 10.1248/cpb.c20-00958

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  50. Relative bradycardia as a clinical feature in patients with coronavirus disease 2019 (COVID-19): A report of two cases.

    Hiraiwa H, Goto Y, Nakamura G, Yasuda Y, Sakai Y, Kasugai D, Jinno S, Tanaka T, Ogawa H, Higashi M, Yamamoto T, Jingushi N, Ozaki M, Numaguchi A, Kondo T, Morimoto R, Okumura T, Matsuda N, Murohara T

    Journal of cardiology cases   Vol. 22 ( 6 ) page: 260 - 264   2020.12

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    DOI: 10.1016/j.jccase.2020.07.015

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  51. Aortic insufficiency associated with Impella that required surgical intervention upon implantation of the durable left ventricular assist device

    Oishi Hideo, Kondo Toru, Fujimoto Kazuro, Mutsuga Masato, Morimoto Ryota, Hirano Ken-ichi, Sawamura Akinori, Kazama Shingo, Kimura Yuki, Shibata Naoki, Kato Hiroo, Arao Yoshihito, Kuwayama Tasuku, Yamaguchi Shogo, Hiraiwa Hiroaki, Okumura Takahiro, Usui Akihiko, Murohara Toyoaki

    JOURNAL OF ARTIFICIAL ORGANS   Vol. 23 ( 4 ) page: 378 - 382   2020.12

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  52. Efficacy of right ventricular dysfunction estimated by pulmonary artery pulsatility index in stable phased dilated cardiomyopathy

    Kuwayama T., Morimoto R., Oishi H., Kato H., Kimura Y., Kazama S., Shibata N., Arao Y., Yamaguchi S., Hiraiwa H., Kondo T., Furusawa K., Okumura T., Murohara T.

    EUROPEAN HEART JOURNAL   Vol. 41   page: 902 - 902   2020.11

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  53. Associations between spleen volume and exercise capacity in advanced heart failure patients with left ventricular assist device

    Hiraiwa H., Okumura T., Sawamura A., Kazama S., Kimura Y., Shibata N., Arao Y., Oishi H., Kato H., Kuwayama T., Yamaguchi S., Kondo T., Furusawa K., Morimoto R., Murohara T.

    EUROPEAN HEART JOURNAL   Vol. 41   page: 1094 - 1094   2020.11

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  54. The efficacy of methotrexate for intolerance to prednisolone therapy in cardiac sarcoidosis

    Morimoto R., Kuwayama T., Ooishi H., Kazama S., Kimura Y., Shibata N., Hiraiwa H., Kondo T., Okumura T., Unno K., Murohara T.

    EUROPEAN HEART JOURNAL   Vol. 41   page: 2131 - 2131   2020.11

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  55. The prognostic impact of right ventricular dysfunction in patients with septic cardiomyopathy

    Hiraiwa H., Kasugai D., Okumura T., Kazama S., Kimura Y., Shibata N., Arao Y., Oishi H., Kato H., Kuwayama T., Yamaguchi S., Kondo T., Furusawa K., Morimoto R., Murohara T.

    EUROPEAN HEART JOURNAL   Vol. 41   page: 1836 - 1836   2020.11

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  56. Transcriptional shifts in delignification-defective mutants of the white-rot fungus Pleurotus ostreatus.

    Wu H, Nakazawa T, Takenaka A, Kodera R, Morimoto R, Sakamoto M, Honda Y

    FEBS letters   Vol. 594 ( 19 ) page: 3182 - 3199   2020.10

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    DOI: 10.1002/1873-3468.13890

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  57. Differential Diagnosis of Mechanisms of Exercise-Induced Abnormal Blood Pressure Response in Hypertrophic Cardiomyopathy Without Left Ventricular Outflow Tract Obstruction

    Okumura Takahiro, Kano Naoaki, Sawamura Akinori, Kondo Toru, Hiraiwa Hiroaki, Morimoto Ryota, Murohara Toyoaki

    CIRCULATION-HEART FAILURE   Vol. 13 ( 10 ) page: e007164   2020.10

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  58. Impella 5.0 for Cardiogenic Shock After Thrombectomy in a Patient With Intraventricular Thrombosis

    Kimura Yuki, Kondo Toru, Mutsuga Masato, Morimoto Ryota, Kazama Shingo, Shibata Naoki, Oishi Hideo, Arao Yoshihito, Kuwayama Tasuku, Kato Hiroo, Yamaguchi Shogo, Hiraiwa Hiroaki, Okumura Takahiro, Fujimoto Kazuro, Usui Akihiko, Murohara Toyoaki

    CANADIAN JOURNAL OF CARDIOLOGY   Vol. 36 ( 10 ) page: 1690.e13 - 1690.e15   2020.10

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  59. Highly Sensitive Labeling Reagents for Scarce Natural Products.

    Kuranaga T, Minote M, Morimoto R, Pan C, Ogawa H, Kakeya H

    ACS chemical biology   Vol. 15 ( 9 ) page: 2499 - 2506   2020.9

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    DOI: 10.1021/acschembio.0c00517

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  60. Successful weaning from veno-arterial ECMO and Impella2.5 by veno-venous and arterial ECMO (v-ECPELLA) for a patient with acute myocardial infarction complicated by severe lung injury.

    Shimizu S, Shimano M, Shibata Y, Hanaki Y, Kamiya H, Morimoto R, Okumura T, Murohara T

    Journal of cardiology cases   Vol. 22 ( 3 ) page: 103 - 106   2020.9

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    DOI: 10.1016/j.jccase.2020.05.004

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  61. Comparison of quantitative assessment for cardiac sarcoidosis inflammation site using F-18-FDG PET/CT images

    Murayama R., Morimoto R., Fujita N., Ito Y., Ono R., Tada T., Ikeda H., Ochi Y., Nishio M., Tsutsumi Y., Tamura M., Odagawa T., Abe S., Kato K.

    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING   Vol. 47 ( SUPPL 1 ) page: S223 - S223   2020.9

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  62. Pulmonary artery pressure may be a predictor of closed aortic valve in patients managed by venoarterial extracorporeal membrane oxygenation

    Yamaguchi Shogo, Sawamura Akinori, Okumura Takahiro, Kato Hiroo, Oishi Hideo, Arao Yoshihito, Haga Tomoaki, Kuwayama Tasuku, Yokoi Tsuyoshi, Hiraiwa Hiroaki, Kondo Toru, Morimoto Ryota, Murohara Toyoaki

    INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS   Vol. 43 ( 9 ) page: 594 - 599   2020.9

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  63. Fulminant myocarditis with myositis of ocular and respiratory muscles

    Hiraiwa Hiroaki, Furusawa Kenji, Kazama Shingo, Kimura Yuki, Shibata Naoki, Arao Yoshihito, Oishi Hideo, Kato Hiroo, Kuwayama Tasuku, Yamaguchi Shogo, Kondo Toru, Sawamura Akinori, Morimoto Ryota, Okumura Takahiro, Murohara Toyoaki

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 82 ( 3 ) page: 585 - 593   2020.8

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  64. Spleen size improvement in advanced heart failure patients using a left ventricular assist device

    Hiraiwa Hiroaki, Okumura Takahiro, Sawamura Akinori, Kondo Toru, Kazama Shingo, Kimura Yuki, Shibata Naoki, Arao Yoshihito, Oishi Hideo, Kato Hiroo, Kuwayama Tasuku, Yamaguchi Shogo, Furusawa Kenji, Morimoto Ryota, Murohara Toyoaki

    ARTIFICIAL ORGANS   Vol. 44 ( 7 ) page: 700 - 708   2020.7

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  65. Usefulness of Plasma Branched-Chain Amino Acid Analysis in Predicting Outcomes of Patients with Nonischemic Dilated Cardiomyopathy

    Kimura Yuki, Okumura Takahiro, Kazama Shingo, Shibata Naoki, Oishi Hideo, Arao Yoshihito, Kuwayama Tasuku, Kato Hiroo, Yamaguchi Shogo, Hiraiwa Hiroaki, Kondo Toru, Morimoto Ryota, Murohara Toyoaki

    INTERNATIONAL HEART JOURNAL   Vol. 61 ( 4 ) page: 739 - 747   2020.7

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  66. Pathological changes of the myocardium in reworsening of anthracycline-induced cardiomyopathy after explant of a left ventricular assist device

    Hiraiwa Hiroaki, Okumura Takahiro, Shimizu Shinya, Arao Yoshihito, Oishi Hideo, Kato Hiroo, Kuwayama Tasuku, Yamaguchi Shogo, Haga Tomoaki, Yokoi Tsuyoshi, Kondo Toru, Sugiura Yuki, Kano Naoaki, Watanabe Naoki, Fukaya Kenji, Furusawa Kenji, Sawamura Akinori, Morimoto Ryota, Fujimoto Kazuro, Mutsuga Masato, Usui Akihiko, Murohara Toyoaki

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 82 ( 1 ) page: 129 - 134   2020.2

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  67. Giant cell myocarditis with central diabetes insipidus: A case report.

    Yamaguchi S, Sawamura A, Nakaguro M, Shimoyama Y, Morimoto R, Kato H, Arao Y, Oishi H, Haga T, Kuwayama T, Yokoi T, Hiraiwa H, Kondo T, Okumura T, Murohara T

    Journal of cardiology cases   Vol. 21 ( 1 ) page: 8 - 11   2020.1

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    DOI: 10.1016/j.jccase.2019.08.011

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  68. Potential prognostic implications of myocardial thallium-201 and iodine-123-beta-methylpentadecanoic acid dual scintigraphy in patients with Anderson-Fabry disease

    Haga Tomoaki, Okumura Takahiro, Isobe Satoshi, Somura Fuji, Kano Naoaki, Kuwayama Tasuku, Yokoi Tsuyoshi, Hiraiwa Hiroaki, Kondo Toru, Sawamura Akinori, Morimoto Ryota, Yamamoto Hiroshi, Tsuboi Kazuya, Murohara Toyoaki

    ANNALS OF NUCLEAR MEDICINE   Vol. 33 ( 12 ) page: 930 - 936   2019.12

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  69. Prognostic impact of mitral L-wave in patients with hypertrophic cardiomyopathy without risk factors for sudden cardiac death Reviewed

    Sugiura Yuki, Morimoto Ryota, Aoki Soichiro, Yamaguchi Shogo, Haga Tomoaki, Kuwayama Tasuku, Yokoi Tsuyoshi, Hiraiwa Hiroaki, Kondo Toru, Watanabe Naoki, Kano Naoaki, Fukaya Kenji, Sawamura Akinori, Okumura Takahiro, Murohara Toyoaki

    HEART AND VESSELS   Vol. 34 ( 12 ) page: 2002 - 2010   2019.12

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    DOI: 10.1007/s00380-019-01440-y

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  70. Circulating human epididymis protein 4 is a novel prognostic predictor in ambulatory patients with non-ischemic dilated cardiomyopathy

    Okumura T., Oishi H., Kondo T., Arao Y., Kato H., Haga T., Yamaguchi S., Kuwayama T., Yokoi T., Hiraiwa H., Sawamura A., Morimoto R., Murohara T.

    EUROPEAN HEART JOURNAL   Vol. 40   page: 4051 - 4051   2019.10

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  71. Early blood pressure reduction by intravenous vasodilators associates with acute kidney injury in patients with hypertensive acute decompensated heart failure

    Arao Y., Sawamura A., Nakatochi M., Oishi H., Kato H., Yamaguchi S., Haga T., Kuwayama T., Yokoi T., Hiraiwa H., Kondo T., Morimoto R., Okumura T., Murohara T.

    EUROPEAN HEART JOURNAL   Vol. 40   page: 884 - 884   2019.10

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  72. Pulmonary artery pressure could predict closed aortic valve in patients managed by veno-arterial extracorporeal membrane oxygenation

    Yamaguchi S., Sawamura A., Arao Y., Ooishi H., Kato H., Kuwayama T., Haga T., Hiraiwa H., Yokoi T., Kondo T., Morimoto R., Okumura T., Murohara T.

    EUROPEAN HEART JOURNAL   Vol. 40   page: 953 - 953   2019.10

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  73. The increased serum level of troponin T after immunosuppression therapy reflects sustained myocardial FDG accumulation in cardiac sarcoidosis

    Morimoto R., Unno K., Ooishi H., Arao Y., Kato H., Yokoi T., Yamaguchi S., Haga T., Kuwayama T., Hiraiwa H., Kondo T., Sawamura A., Okumura T., Murohara T.

    EUROPEAN HEART JOURNAL   Vol. 40   page: 648 - 648   2019.10

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  74. Splenic volume changes as a hemodynamic parameter in advanced heart failure with left ventricular assist device

    Hiraiwa H., Okumura T., Sawamura A., Kondo T., Arao Y., Oishi H., Kato H., Kuwayama T., Yamaguchi S., Haga T., Yokoi T., Fukaya K., Furusawa K., Morimoto R., Murohara T.

    EUROPEAN HEART JOURNAL   Vol. 40   page: 3303 - 3303   2019.10

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  75. Early Blood Pressure Reduction by Intravenous Vasodilators Is Associated With Acute Kidney Injury in Patients With Hypertensive Acute Decompensated Heart

    Arao Yoshihito, Sawamura Akinori, Nakatochi Masahiro, Okumura Takahiro, Kato Hiroo, Oishi Hideo, Yamaguchi Shogo, Haga Tomoaki, Kuwayama Tasuku, Yokoi Tsuyoshi, Hiraiwa Hiroaki, Kondo Toru, Morimoto Ryota, Murohara Toyoaki

    CIRCULATION JOURNAL   Vol. 83 ( 9 ) page: 1883 - +   2019.9

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  76. Left Ventricular Relaxation Half-Time as a Predictor of Cardiac Events in Idiopathic Dilated Cardiomyopathy and Hypertrophic Cardiomyopathy With Left Ventricular Systolic and/or Diastolic Dysfunction

    Yokoi Tsuyoshi, Morimoto Ryota, Oishi Hideo, Kato Hiroo, Arao Yoshihito, Yamaguchi Shogo, Kuwayama Tasuku, Haga Tomoaki, Hiraiwa Hiroaki, Kondo Toni, Furusawa Kenji, Fukaya Kenji, Sawamura Akinori, Okumura Takahiro, Hirashiki Akihiro, Murohara Toyoaki

    AMERICAN JOURNAL OF CARDIOLOGY   Vol. 124 ( 3 ) page: 435 - 441   2019.8

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  77. A survival case of a young adult patient with ST-elevated myocardial infarction with high levels of lipoprotein(a).

    Hiraiwa H, Morimoto R, Okumura T, Arao Y, Oishi H, Kato H, Yamaguchi S, Kuwayama T, Haga T, Yokoi T, Kondo T, Watanabe N, Mitsuda T, Fukaya K, Sawamura A, Tanaka A, Ishii H, Morishima I, Tsuboi H, Murohara T

    Journal of cardiology cases   Vol. 19 ( 6 ) page: 207 - 210   2019.6

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    DOI: 10.1016/j.jccase.2019.02.004

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  78. Dominant effects of gat1 mutations on the ligninolytic activity of the white-rot fungus Pleurotus ostreatus.

    Nakazawa T, Morimoto R, Wu H, Kodera R, Sakamoto M, Honda Y

    Fungal biology   Vol. 123 ( 3 ) page: 209 - 217   2019.3

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    DOI: 10.1016/j.funbio.2018.12.007

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  79. Prognostic value of left ventricular dyssynchrony evaluated by gated myocardial perfusion imaging in patients with chronic kidney disease and normal perfusion defect scores

    Mori Hiroaki, Isobe Satoshi, Suzuki Susumu, Unno Kazumasa, Morimoto Ryota, Kano Naoaki, Okumura Takahiro, Yasuda Yoshinari, Kato Katsuhiko, Murohara Toyoaki

    JOURNAL OF NUCLEAR CARDIOLOGY   Vol. 26 ( 1 ) page: 288 - 297   2019.2

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  80. Hemodynamics of cardiac tamponade during extracorporeal membrane oxygenation support in a patient with fulminant myocarditis.

    Kondo T, Morimoto R, Yokoi T, Yamaguchi S, Kuwayama T, Haga T, Hiraiwa H, Sugiura Y, Watanabe N, Kano N, Ichii T, Fukaya K, Sawamura A, Okumura T, Yoshizumi T, Mutsuga M, Fujimoto K, Matsuda N, Usui A, Murohara T

    Journal of cardiology cases   Vol. 19 ( 1 ) page: 22 - 24   2019.1

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    DOI: 10.1016/j.jccase.2018.08.009

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  81. Assessment of abdominal aortic calcification by computed tomography for prediction of latent left ventricular stiffness and future cardiovascular risk in pre-dialysis patients with chronic kidney disease: A single center cross-sectional study

    Furusawa Kenji, Takeshita Kyosuke, Suzuki Susumu, Tatami Yosuke, Morimoto Ryota, Okumura Takahiro, Yasuda Yoshinari, Murohara Toyoaki

    INTERNATIONAL JOURNAL OF MEDICAL SCIENCES   Vol. 16 ( 7 ) page: 939 - 948   2019

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  82. Left ventricular phase entropy: Novel prognostic predictor in patients with dilated cardiomyopathy and narrow QRS

    Kano Naoaki, Okumura Takahiro, Isobe Satoshi, Sawamura Akinori, Watanabe Naoki, Fukaya Kenji, Mori Hiroaki, Morimoto Ryota, Kato Katsuhiko, Bando Yasuko K., Murohara Toyoaki

    JOURNAL OF NUCLEAR CARDIOLOGY   Vol. 25 ( 5 ) page: 1677 - 1687   2018.10

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  83. Promising method for management of venoarterial extracorporeal membrane oxygenation: A case of severe heart failure successfully stabilized by "high-flow/vasodilation method".

    Kondo T, Sawamura A, Okumura T, Kano N, Morimoto R, Watanabe N, Hiraiwa H, Kuwayama T, Sugiura Y, Haga T, Yamaguchi S, Fukaya K, Yokoi T, Fujimoto K, Mutsuga M, Yoshizumi T, Matsuda N, Usui A, Murohara T

    Journal of cardiology cases   Vol. 18 ( 2 ) page: 81 - 84   2018.8

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    DOI: 10.1016/j.jccase.2018.05.002

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  84. Tau as a predictor of cardiac events in cardiomyopathy with systolic and/or diastolic dysfunction

    Yokoi T., Morimoto R., Okumura T., Yamaguchi S., Kuwayama T., Hiraiwa H., Haga T., Kondo T., Sugiura Y., Watanabe N., Kano N., Sawamura A., Murohara T.

    EUROPEAN HEART JOURNAL   Vol. 39   page: 1386 - 1387   2018.8

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  85. Late-Onset Fulminant Myocarditis With Immune Checkpoint Inhibitor Nivolumab

    Yamaguchi Shogo, Morimoto Ryota, Okumura Takahiro, Yamashita Yuta, Haga Tomoaki, Kuwayama Tasuku, Yokoi Tsuyoshi, Hiraiwa Hiroaki, Kondo Toru, Sugiura Yuki, Watanabe Naoki, Kano Naoaki, Kohno Kei, Fukaya Kenji, Sawamura Akinori, Yokota Kenji, Ishii Hideki, Nakaguro Masato, Akiyama Masashi, Murohara Toyoaki

    CANADIAN JOURNAL OF CARDIOLOGY   Vol. 34 ( 6 ) page: 812.e1 - 812.e3   2018.6

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  86. The Selvester QRS score as a predictor of cardiac events in nonischemic dilated cardiomyopathy

    Hiraiwa Hiroaki, Okumura Takahiro, Sawamura Akinori, Sugiura Yuki, Kondo Toru, Watanabe Naoki, Aoki Soichiro, Ichii Takeo, Kitagawa Katsuhide, Kano Naoaki, Fukaya Kenji, Furusawa Kenji, Morimoto Ryota, Takeshita Kyosuke, Bando Yasuko K., Murohara Toyoaki

    JOURNAL OF CARDIOLOGY   Vol. 71 ( 3-4 ) page: 284 - 290   2018

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  87. The Selvester QRS score as a predictor of cardiac events in nonischemic dilated cardiomyopathy (vol 71, pg 284, 2018)

    Hiraiwa Hiroaki, Okumura Takahiro, Sawamura Akinori, Sugiura Yuki, Kondo Toru, Watanabe Naoki, Aoki Soichiro, Ichii Takeo, Kitagawa Katsuhide, Kano Naoaki, Fukaya Kenji, Furusawa Kenji, Morimoto Ryota, Takeshita Kyosuke, Bando Yasuko K., Murohara Toyoaki

    JOURNAL OF CARDIOLOGY   Vol. 72 ( 1-2 ) page: 178 - 178   2018

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  88. Sokolow-Lyon voltage is suitable for monitoring improvement in cardiac function and prognosis of patients with idiopathic dilated cardiomyopathy

    Fukaya Kenji, Takeshita Kyosuke, Okumura Takahiro, Hiraiwa Hiroaki, Aoki Soichiro, Ichii Takeo, Sugiura Yuki, Kitagawa Katsuhide, Kondo Toru, Watanabe Naoki, Kano Naoaki, Furusawa Kenji, Sawamura Akinori, Morimoto Ryota, Bando Yasuko, Murohara Toyoaki

    ANNALS OF NONINVASIVE ELECTROCARDIOLOGY   Vol. 22 ( 5 )   2017.9

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  89. Human exposure to pulsed fields in the frequency range from 6 to 100 GHz.

    Laakso I, Morimoto R, Heinonen J, Jokela K, Hirata A

    Physics in medicine and biology   Vol. 62 ( 17 ) page: 6980 - 6992   2017.8

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    DOI: 10.1088/1361-6560/aa81fe

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  90. Is the administration of mineralocorticoid receptor antagonist required in asymptomatic AHA/ACC stage B heart failure patients?

    Okumura T., Sawamura A., Sugiura Y., Hiraiwa H., Kondo T., Aoki S., Watanabe N., Kano N., Fukaya K., Morimoto R., Bando Y. K., Murohara T.

    EUROPEAN HEART JOURNAL   Vol. 38   page: 698 - 698   2017.8

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  91. The Selvester QRS score as a predictor of cardiac events in nonischemic dilated cardiomyopathy

    Hiraiwa H., Okumura T., Sawamura A., Sugiura Y., Kondo T., Watanabe N., Aoki S., Ichii T., Kano N., Fukaya K., Furusawa K., Morimoto R., Takeshita K., Bando Y., Murohara T.

    EUROPEAN HEART JOURNAL   Vol. 38   page: 143 - 144   2017.8

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  92. Corticotropin releasing hormone receptor 2 exacerbates chronic cardiac dysfunction

    Tsuda Takuma, Takefuji Mikito, Wettschureck Nina, Kotani Kazuhiko, Morimoto Ryota, Okumura Takahiro, Kaur Harmandeep, Eguchi Shunsuke, Sakaguchi Teruhiro, Ishihama Sohta, Kikuchi Ryosuke, Unno Kazumasa, Matsushita Kunihiro, Ishikawa Shizukiyo, Offermanns Stefan, Murohara Toyoaki

    JOURNAL OF EXPERIMENTAL MEDICINE   Vol. 214 ( 7 ) page: 1877 - 1888   2017.7

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  93. Usefulness of the Combination of In-Hospital Poor Diuretic Response and Systemic Congestion to Predict Future Cardiac Events in Patients With Acute Decompensated Heart Failure

    Aoki Soichiro, Okumura Takahiro, Sawamura Akinori, Kitagawa Katsuhide, Morimoto Ryota, Sakakibara Masaki, Murohara Toyoaki

    AMERICAN JOURNAL OF CARDIOLOGY   Vol. 119 ( 12 ) page: 2010 - 2016   2017.6

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  94. On the averaging area for incident power density for human exposure limits at frequencies over 6 GHz.

    Hashimoto Y, Hirata A, Morimoto R, Aonuma S, Laakso I, Jokela K, Foster KR

    Physics in medicine and biology   Vol. 62 ( 8 ) page: 3124 - 3138   2017.4

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    DOI: 10.1088/1361-6560/aa5f21

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  95. Impact of Skeletal Muscle Mass on Long-Term Adverse Cardiovascular Outcomes in Patients With Chronic Kidney Disease

    Harada Kazuhiro, Suzuki Susumu, Ishii Hideki, Aoki Toshijiro, Hirayama Kenshi, Shibata Yohei, Negishi Yosuke, Sumi Takuya, Kawashima Kazuhiro, Kunimura Ayako, Shimbo Yusaku, Tatami Yosuke, Kawamiya Toshiki, Yamamoto Dai, Morimoto Ryota, Yasuda Yoshinari, Murohara Toyoaki

    AMERICAN JOURNAL OF CARDIOLOGY   Vol. 119 ( 8 ) page: 1275 - 1280   2017.4

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  96. Compensated Cell Enlargement in fugu5 is Specifically Triggered by Lowered Sucrose Production from Seed Storage Lipids

    Takahashi Kazuki, Morimoto Ryousuke, Tabeta Hiromitsu, Asaoka Mariko, Ishida Masanori, Maeshima Masayoshi, Tsukaya Hirokazu, Ferjani Ali

    PLANT AND CELL PHYSIOLOGY   Vol. 58 ( 4 ) page: 668 - 678   2017.4

  97. Time constants for temperature elevation in human models exposed to dipole antennas and beams in the frequency range from 1 to 30 GHz.

    Morimoto R, Hirata A, Laakso I, Ziskin MC, Foster KR

    Physics in medicine and biology   Vol. 62 ( 5 ) page: 1676 - 1699   2017.3

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    DOI: 10.1088/1361-6560/aa5251

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  98. Biphasic Force-Frequency Relation Predicts Primary Cardiac Events in Patients With Hypertrophic Cardiomyopathy

    Morimoto Ryota, Okumura Takahiro, Bando Yasuko K., Fukaya Kenji, Sawamura Akinori, Kawase Haruya, Shimizu Shinya, Shimazu Shuzo, Hirashiki Akihiro, Takeshita Kyosuke, Murohara Toyoaki

    CIRCULATION JOURNAL   Vol. 81 ( 3 ) page: 368 - 375   2017.3

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  99. Nutrition Status Predicts Severity of Vascular Calcification in Non-Dialyzed Chronic Kidney Disease

    Harada Kazuhiro, Suzuki Susumu, Ishii Hideki, Hirayama Kenshi, Aoki Toshijiro, Shibata Yohei, Negishi Yosuke, Sumi Takuya, Kawashima Kazuhiro, Kunimura Ayako, Tatami Yosuke, Kawamiya Toshiki, Yamamoto Dai, Morimoto Ryota, Yasuda Yoshinari, Murohara Toyoaki

    CIRCULATION JOURNAL   Vol. 81 ( 3 ) page: 316 - 321   2017.3

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  100. Long-Term Pathological Follow-Up of Myocardium in a Carrier of Duchenne Muscular Dystrophy With Dilated Cardiomyopathy

    Kondo Toru, Okumura Takahiro, Takefuji Mikito, Hiraiwa Hiroaki, Sugiura Yuki, Watanabe Naoki, Aoki Soichiro, Ichii Takeo, Kitagawa Katsuhide, Kano Naoaki, Fukaya Kenji, Furusawa Kenji, Sawamura Akinori, Morimoto Ryota, Bando Yasuko K., Takemura Genzou, Murohara Toyoaki

    CIRCULATION-HEART FAILURE   Vol. 10 ( 3 ) page: e003826   2017.3

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  101. Abnormal Circadian Blood Pressure Profile as a Prognostic Marker in Patients with Nonischemic Dilated Cardiomyopathy

    Sawamura Akinori, Okumura Takahiro, Takeshita Kyosuke, Watanabe Naoki, Kano Naoaki, Mori Hiroaki, Fukaya Kenji, Morimoto Ryota, Hirashiki Akihiro, Bando Yasuko Kureishi, Murohara Toyoaki

    CARDIOLOGY   Vol. 136 ( 1 ) page: 1 - 9   2017

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  102. Myocardial contractile reserve predicts left ventricular reverse remodeling and cardiac events in dilated cardiomyopathy

    Morimoto Ryota, Okumura Takahiro, Hirashiki Akihiro, Ishii Hideki, Ichii Takeo, Aoki Soichiro, Furusawa Kenji, Hiraiwa Hiroaki, Kondo Toru, Watanabe Naoki, Kano Naoaki, Fukaya Kenji, Sawamura Akinori, Takeshita Kyosuke, Bando Yasuko K., Murohara Toyoaki

    JOURNAL OF CARDIOLOGY   Vol. 70 ( 3-4 ) page: 303 - 309   2017

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  103. Impact of Renal Functional/Morphological Dynamics on the Calcification of Coronary and Abdominal Arteries in Patients with Chronic Kidney Disease

    Ichii Takeo, Morimoto Ryota, Okumura Takahiro, Ishii Hideki, Tatami Yosuke, Yamamoto Dai, Aoki Soichiro, Hiraiwa Hiroaki, Furusawa Kenji, Kondo Toru, Watanabe Naoki, Kano Naoaki, Fukaya Kenji, Sawamura Akinori, Suzuki Susumu, Yasuda Yoshinari, Murohara Toyoaki

    JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS   Vol. 24 ( 11 ) page: 1092 - 1104   2017

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  104. Cholesterol metabolism as a prognostic marker in patients with mildly symptomatic nonischemic dilated cardiomyopathy

    Sawamura Akinori, Okumura Takahiro, Hiraiwa Hiroaki, Aoki Soichiro, Kondo Toru, Ichii Takeo, Furusawa Kenji, Watanabe Naoki, Kano Naoaki, Fukaya Kenji, Morimoto Ryota, Bando Yasuko K., Murohara Toyoaki

    JOURNAL OF CARDIOLOGY   Vol. 69 ( 5-6 ) page: 888 - 894   2017

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Books 1

  1. 腫瘍循環器診療ハンドブック Reviewed

    ( Role: Joint author ,  がん治療薬による心血管合併症一覧)

    MEDICAL VIEW 

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    Language:Japanese

KAKENHI (Grants-in-Aid for Scientific Research) 4

  1. 免疫チェックポイント阻害薬による自己抗体関連有害事象の検証を目的とした研究

    Grant number:22K08178  2022.4 - 2026.3

    科学研究費助成事業  基盤研究(C)

    森本 竜太, 加藤 勝洋, 暮石泰子

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    Authorship:Principal investigator 

    Grant amount:\3510000 ( Direct Cost: \2700000 、 Indirect Cost:\810000 )

    免疫チェックポイント阻害薬(ICI)は従来の抗がん薬とは一線を画す作用機序により画期的な治療効果を有し、現在適応症も拡大の一途をたどっているが、過剰な細胞障害性T細胞 は様々な臓器に重篤な副作用(免疫関連有害事象:irAE)を引き起こし、正常な心筋をも攻撃しがん患者の生命予後に大きく影響を来すものとして心血管irAEが挙げられる。心血管irAEに関する発症予測因子や免疫学的な関連メカニズムの解明が望まれるが、近年、がん病巣拡大の指標として注目されている可溶性免疫チェックポイント分子(sPD-L1)が心血管irAE発症時より上昇をするため、臨床上有用なバイオマーカと成り得るかを検証する。
    当院ではがん化学療法関連心血管合併症のチャートレビュー(承認番号 2019-0176)研究を行ってきており、2021年 Prognostic impact of immune-related adverse events on patients with and without cardiovascular disease: a retrospective review をCardiooncologyに投稿済である。(2021 Jul 6;7(1):26. doi: 10.1186/s40959-021-00112-z)。2020年9月からは化学療法部と循環器内科連携でICI投与患者全例に対して、左心機能の僅かな変化の検出にも有用とされる心エコーでのgloballongitudinal strain (GLS)評価や定期的な血液検査を多科共同で行う体制を構築し、稼働を開始しており、2020年4月27日以降 登録患者数は499人となっている。心筋炎を合併した症例に関しては心筋生検を行い、HE染色に加えて、CD3, 4, 8, 20, 68, PD-1, PD-L1 染色を行い、病態と免疫染色との関連に関して更なる解析を行ってきた。また他臓器におけるirAE と心血管合併症との関連やその後の予後に関してや心エコー上のGLS データとバイオマーカとの関連に関しても着実にデータ収集ができている。
    2022年度の研究計画通り、概ね順調に進行をしている。
    2022年度以降、複数の劇症型心筋炎症例を経験している。これらの血液検体からヒト蛋白マイクロアレイを用いて、自己抗体の同定を目指す。

  2. Prospectively Analysis of Cardiac Sarcoidosis with Immunosuppressive Therapy

    Grant number:18K15387  2018.4 - 2021.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Early-Career Scientists

    Morimoto Ryota

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    Authorship:Principal investigator 

    Grant amount:\3510000 ( Direct Cost: \2700000 、 Indirect Cost:\810000 )

    We prospectively enrolled CS patients with abnormal FDG accumulation in the heart (n=56) from October 2016, and calculated total lesion glycolysis (TLG) before and after treatment to evaluate the response to treatment. Patients in the Poor Responder group were randomly divided into two groups: PSL re-increase group and MTX intervention group as intensification therapy. After six months of PSL treatment, about 85% of patients showed a reduction in TLG of 70% or more. However, in the treatment-resistant group, neither re-PSL nor MTX had a significant effect on TLG reduction.

  3. Pathophysiological significance of the Klotho-FGF system in myocardial diseases

    Grant number:16K09429  2016.4 - 2020.3

    Okumura Takahiro

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    Authorship:Coinvestigator(s) 

    We examined the relationship between serum FGF-23 levels and biomarkers, hemodynamics, and prognosis in 42 patients with dilated cardiomyopathy. FGF-23 levels in peripheral vein was negatively correlated with estimated glomerular filtration rate and positively with high-sensitivity troponin T levels. In survival analysis, the cardiac event rate was significantly higher in the High FGF-23 group than in the Low FGF-23 group. In multivariate analysis, the high FGF-23 group was an independent predictor of cardiac events. In multiple regression analysis, the estimated glomerular filtration rate and brain natriuretic peptide levels were significant determinants of FGF-23 levels. Collagen volume fraction in endomyocardial biopsy samples was not significantly correlated with peripheral FGF-23 levels, but was weakly correlated with the transcardiac gradient of FGF-23 levels defined as the difference in concentration between the coronary sinus and the base of the aorta.

  4. Mechanism Analysis of Microcirculation Disorder in Hypertrophic Cardiomyopathy

    Grant number:16K19398  2016.4 - 2019.3

    Ryota Morimoto

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    Authorship:Principal investigator 

    Grant amount:\3900000 ( Direct Cost: \3000000 、 Indirect Cost:\900000 )

    Hypertrophic cardiomyopathy (HCM) is characterized by gradual thickening of the cardiac muscle and impairing myocardial blood flow (MBF). We assessed MBF undergoing NH3-PET and in order to perform transmural layer analysis, the reconstructed images were transferred to a workstation using PMOD software. We enrolled 17 control patients and 16 HCM patients. Even though there was no significant difference between control patients and HCM patients in subendocardial MBF at rest, hyperemic subendocardial MBF in HCM was significantly lower than normal patients (1.159±0.144 vs 1.422±0.202, p=0.0002). Furthermore, HOCM was significantly lower than apical HCM patients (1.32±0.18 vs 1.92±0.49). These results might relate the major cause of sudden cardiac death due to latent myocardial damage in HOCM patients.