Faculty Profiles - KUSHIMA Itaru

Papers - KUSHIMA Itaru

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Effect of intranasal oxytocin on the core social symptoms of autism spectrum disorder: a randomized clinical trial Reviewed

Yamasue, H; Okada, T; Munesue, T; Kuroda, M; Fujioka, T; Uno, Y; Matsumoto, K; Kuwabara, H; Mori, D; Okamoto, Y; Yoshimura, Y; Kawakubo, Y; Arioka, Y; Kojima, M; Yuhi, T; Owada, K; Yassin, W; Kushima, I; Benner, S; Ogawa, N; Eriguchi, Y; Kawano, N; Uemura, Y; Yamamoto, M; Kano, Y; Kasai, K; Higashida, H; Ozaki, N; Kosaka, H

MOLECULAR PSYCHIATRY Vol. 25 ( 8 ) page： 1849 - 1858 2020.8

<i>ARHGAP10</i>, which encodes Rho GTPase-activating protein 10, is a novel gene for schizophrenia risk Reviewed

Sekiguchi, M; Sobue, A; Kushima, I; Wang, CY; Arioka, Y; Kato, H; Kodama, A; Kubo, H; Ito, N; Sawahata, M; Hada, K; Ikeda, R; Shinno, M; Mizukoshi, C; Tsujimura, K; Yoshimi, A; Ishizuka, K; Takasaki, Y; Kimura, H; Xing, JR; Yu, YJ; Yamamoto, M; Okada, T; Shishido, E; Inada, T; Nakatochi, M; Takano, T; Kuroda, K; Amano, M; Aleksic, B; Yamomoto, T; Sakuma, T; Aida, T; Tanaka, K; Hashimoto, R; Arai, M; Ikeda, M; Iwata, N; Shimamura, T; Nagai, T; Nabeshima, T; Kaibuchi, K; Yamada, K; Mori, D; Ozaki, N

TRANSLATIONAL PSYCHIATRY Vol. 10 ( 1 ) 2020.7

A recurrentPJA1variant in trigonocephaly and neurodevelopmental disorders Reviewed

Suzuki Toshimitsu, Suzuki Toshifumi, Raveau Matthieu, Miyake Noriko, Sudo Genki, Tsurusaki Yoshinori, Watanabe Takaki, Sugaya Yuki, Tatsukawa Tetsuya, Mazaki Emi, Shimohata Atsushi, Kushima Itaru, Aleksic Branko, Shiino Tomoko, Toyota Tomoko, Iwayama Yoshimi, Nakaoka Kentaro, Ohmori Iori, Sasaki Aya, Watanabe Ken, Hirose Shinichi, Kaneko Sunao, Inoue Yushi, Yoshikawa Takeo, Ozaki Norio, Kano Masanobu, Shimoji Takeyoshi, Matsumoto Naomichi, Yamakawa Kazuhiro

ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY Vol. 7 ( 7 ) page： 1117 - 1131 2020.7

Generation and analysis of novel Reln-deleted mouse model corresponding to exonic Reln deletion in schizophrenia Reviewed

Sawahata Masahito, Mori Daisuke, Arioka Yuko, Kubo Hisako, Kushima Itaru, Kitagawa Kanako, Sobue Akira, Shishido Emiko, Sekiguchi Mariko, Kodama Akiko, Ikeda Ryosuke, Aleksic Branko, Kimura Hiroki, Ishizuka Kanako, Nagai Taku, Kaibuchi Kozo, Nabeshima Toshitaka, Yamada Kiyofumi, Ozaki Norio

PSYCHIATRY AND CLINICAL NEUROSCIENCES Vol. 74 ( 5 ) page： 318 - 327 2020.5

Cell body shape and directional movement stability in human-induced pluripotent stem cell-derived dopaminergic neurons Reviewed

Arioka Yuko, Shishido Emiko, Kushima Itaru, Mori Daisuke, Ozaki Norio

SCIENTIFIC REPORTS Vol. 10 ( 1 ) 2020.4

Cutting-edge morphological studies of post-mortem brains of patients with schizophrenia and potential applications of X-ray nanotomography (nano-CT)

Itokawa Masanari, Oshima Kenichi, Arai Makoto, Torii Yota, Kushima Itaru, Iritani Shuji, Ozaki Norio, Saiga Rino, Mizutani Ryuta

PSYCHIATRY AND CLINICAL NEUROSCIENCES Vol. 74 ( 3 ) page： 176 - 182 2020.3

Comprehensive analysis of a novel mouse model of the 22q11.2 deletion syndrome: a model with the most common 3.0-Mb deletion at the human 22q11.2 locus

Saito Ryo, Koebis Michinori, Nagai Taku, Shimizu Kimiko, Liao Jingzhu, Wulaer Bolati, Sugaya Yuki, Nagahama Kenichiro, Uesaka Naofumi, Kushima Itaru, Mori Daisuke, Maruyama Kazuaki, Nakao Kazuki, Kurihara Hiroki, Yamada Kiyofumi, Kano Masanobu, Fukada Yoshitaka, Ozaki Norio, Aiba Atsu

TRANSLATIONAL PSYCHIATRY Vol. 10 ( 1 ) 2020.2

Characterization of a schizophrenia patient with a rare RELN deletion by combining genomic and patient-derived cell analyses

Arioka Yuko, Hirata Akihiro, Kushima Itaru, Aleksic Branko, Mori Daisuke, Ozaki Norio

SCHIZOPHRENIA RESEARCH Vol. 216 page： 511 - 515 2020.2

Polygenic risk scores in schizophrenia with clinically significant copy number variants

Taniguchi Satoru, Ninomiya Kohei, Kushima Itaru, Saito Takeo, Shimasaki Ayu, Sakusabe Takaya, Momozawa Yukihide, Kubo Michiaki, Kamatani Yoichiro, Ozaki Norio, Ikeda Masashi, Iwata Nakao

PSYCHIATRY AND CLINICAL NEUROSCIENCES Vol. 74 ( 1 ) page： 35 - 39 2020.1

A network of networks approach for modeling interconnected brain tissue-specific networks

Kawakubo Hideko, Matsui Yusuke, Kushima Itaru, Ozaki Norio, Shimamura Teppei

BIOINFORMATICS Vol. 35 ( 17 ) page： 3092 - 3101 2019.9

In Vitro Modeling of the Bipolar Disorder and Schizophrenia Using Patient-Derived Induced Pluripotent Stem Cells with Copy Number Variations of PCDH15 and RELN

Ishii Takaya, Ishikawa Mitsuru, Fujimori Koki, Maeda Takuji, Kushima Itaru, Arioka Yuko, Mori Daisuke, Nakatake Yuhki, Yamagata Bun, Nio Shintaro, Kato Takahiro A., Yang Nan, Wernig Marius, Kanba Shigenobu, Mimura Masaru, Ozaki Norio, Okano Hideyuki

ENEURO Vol. 6 ( 5 ) 2019.9

Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect

Ikeda Masashi, Takahashi Atsushi, Kamatanim Yoichiro, Momozawa Yukihide, Saito Takeo, Kondo Kenji, Shimasaki Ayu, Kawase Kohei, Sakusabe Takaya, Iwayama Yoshimi, Toyota Tomoko, Wakudas Tomoyasu, Kikuchi Mitsuru, Kanahara Nobuhisa, Yamamori Hidenaga, Yasuda Yuka, Watanabe Yuichiro, Hoya Satoshi, Aleksic Branko, Kushima Itaru, Arai Heii, Takaki Manabu, Hattori Kotaro, Kurrugi Hiroshi, Okahisa Yuko, Ohnuma Tohru, Ozaki Norio, Someya Toshiyuki, Hashimotovs Ryota, Yoshikawa Takeo, Kubo Michiaki, Iwata Nakao

SCHIZOPHRENIA BULLETIN Vol. 45 ( 4 ) page： 824 - 834 2019.7

Quantitative facial expression analysis revealed the efficacy and time course of oxytocin in autism

Owada Keiho, Okada Takashi, Munesue Toshio, Kuroda Miho, Fujioka Toru, Uno Yota, Matsumoto Kaori, Kuwabara Hitoshi, Mori Daisuke, Okamoto Yuko, Yoshimura Yuko, Kawakubo Yuki, Arioka Yuko, Kojima Masaki, Yuhi Teruko, Yassin Walid, Kushima Itaru, Benner Seico, Ogawa Nanayo, Kawano Naoko, Eriguchi Yosuke, Uemura Yukari, Yamamoto Maeri, Kano Yukiko, Kasai Kiyoto, Higashida Haruhiro, Ozaki Norio, Kosaka Hirotaka, Yamasue Hidenori

BRAIN Vol. 142 page： 2127 - 2136 2019.7

Proteomic analysis of lymphoblastoid cell lines from schizophrenic patients

Yoshimi Akira, Yamada Shinnosuke, Kunimoto Shohko, Aleksic Branko, Hirakawa Akihiro, Ohashi Mitsuki, Matsumoto Yurie, Hada Kazuhiro, Itoh Norimichi, Arioka Yuko, Kimura Hiroki, Kushima Itaru, Nakamura Yukako, Shiino Tomoko, Mori Daisuke, Tanaka Satoshi, Hamada Shuko, Noda Yukihiro, Nagai Taku, Yamada Kiyofumi, Ozaki Norio

TRANSLATIONAL PSYCHIATRY Vol. 9 2019.4

Three-dimensional alteration of neurites in schizophrenia

Mizutani Ryuta, Saiga Rino, Takeuchi Akihisa, Uesugi Kentaro, Terada Yasuko, Suzuki Yoshio, De Andrade Vincent, De Carlo Francesco, Takekoshi Susumu, Inomoto Chie, Nakamura Naoya, Kushima Itaru, Iritani Shuji, Ozaki Norio, Ide Soichiro, Ikeda Kazutaka, Oshima Kenichi, Itokawa Masanari, Arai Makoto

TRANSLATIONAL PSYCHIATRY Vol. 9 2019.2

A NOVEL RARE VARIANT R292H IN RTN4R AFFECTS GROWTH CONE FORMATION AND POSSIBLY CONTRIBUTES TO SCHIZOPHRENIA SUSCEPTIBILITY

Kimura Hiroki, Ishizuka Kanako, Wang Chenyao, Kushima Itaru, Morikawa Mako, Uno Yota, Okada Takashi, Inanda Toshiya, Aleksic Branko, Mori Daisuke, Ozaki Norio

EUROPEAN NEUROPSYCHOPHARMACOLOGY Vol. 29 page： S1014 - S1014 2019

Dysregulation of schizophrenia-related aquaporin 3 through disruption of paranode influences neuronal viability

Kunisawa Kazuo, Shimizu Takeshi, Kushima Itaru, Aleksic Branko, Mori Daisuke, Osanai Yasuyuki, Kobayashi Kenta, Taylor Anna M., Bhat Manzoor A., Hayashi Akiko, Baba Hiroko, Ozaki Norio, Ikenaka Kazuhiro

JOURNAL OF NEUROCHEMISTRY Vol. 147 ( 3 ) page： 395 - 408 2018.11

Assessment of a glyoxalase I frameshift variant, p.P122fs, in Japanese patients with schizophrenia

Ishizuka Kanako, Kimura Hiroki, Kushima Itaru, Inada Toshiya, Okahisa Yuko, Ikeda Masashi, Iwata Nakao, Mori Daisuke, Aleksic Branko, Ozaki Norio

PSYCHIATRIC GENETICS Vol. 28 ( 5 ) page： 90 - 93 2018.10

Comparative Analyses of Copy-Number Variation in Autism Spectrum Disorder and Schizophrenia Reveal Etiological Overlap and Biological Insights Reviewed

Kushima Itaru, Aleksic Branko, Nakatochi Masahiro, Shimamura Teppei, Okada Takashi, Uno Yota, Morikawa Mako, Ishizuka Kanako, Shiino Tomoko, Kimura Hiroki, Arioka Yuko, Yoshimi Akira, Takasaki Yuto, Yu Yanjie, Nakamura Yukako, Yamamoto Maeri, Iidaka Tetsuya, Iritani Shuji, Inada Toshiya, Ogawa Nanayo, Shishido Emiko, Torii Youta, Kawano Naoko, Omura Yutaka, Yoshikawa Toru, Uchiyama Tokio, Yamamoto Toshimichi, Ikeda Masashi, Hashimoto Ryota, Yamamori Hidenaga, Yasuda Yuka, Someya Toshiyuki, Watanabe Yuichiro, Egawa Jun, Nunokawa Ayako, Itokawa Masanari, Arai Makoto, Miyashita Mitsuhiro, Kobori Akiko, Suzuki Michio, Takahashi Tsutomu, Usami Masahide, Kodaira Masaki, Watanabe Kyota, Sasaki Tsukasa, Kuwabara Hitoshi, Tochigi Mamoru, Nishimura Fumichika, Yamasue Hidenori, Eriguchi Yosuke, Benner Seico, Kojima Masaki, Yassin Walid, Munesue Toshio, Yokoyama Shigeru, Kimura Ryo, Funabiki Yasuko, Kosaka Hirotaka, Ishitobi Makoto, Ohmori Tetsuro, Numata Shusuke, Yoshikawa Takeo, Toyota Tomoko, Yamakawa Kazuhiro, Suzuki Toshimitsu, Inoue Yushi, Nakaoka Kentaro, Goto Yu-ichi, Inagaki Masumi, Hashimoto Naoki, Kusumi Ichiro, Son Shuraku, Murai Toshiya, Ikegame Tempei, Okada Naohiro, Kasai Kiyoto, Kunimoto Shohko, Mori Daisuke, Iwata Nakao, Ozaki Norio

CELL REPORTS Vol. 24 ( 11 ) page： 2838 - 2856 2018.9

Aberrant functional connectivity between the thalamus and visual cortex is related to attentional impairment in schizophrenia

Yamamoto, M; Kushima, I; Suzuki, R; Branko, A; Kawano, N; Inada, T; Iidaka, T; Ozaki, N

PSYCHIATRY RESEARCH-NEUROIMAGING Vol. 278 page： 35 - 41 2018.8

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Papers - KUSHIMA Itaru