Updated on 2022/03/17

写真a

 
ISHIZU Yoji
 
Organization
Nagoya University Hospital Gastroenterology Assistant Professor
Graduate School
Graduate School of Medicine
Title
Assistant Professor

Degree 1

  1. 博士(医学) ( 2012.3   名古屋大学 ) 

Professional Memberships 5

  1. 日本肝臓学会   指導医

  2. 日本消化器病学会   専門医

  3. 日本内科学会   総合内科専門医

  4. 門脈圧亢進症学会   会員

  5. 日本超音波医学界   会員

 

Papers 96

  1. Changes in Body Composition Predict the Time to Treatment Failure of Lenvatinib in Patients with Advanced Hepatocellular Carcinoma: A Pilot Retrospective Study.

    Yamamoto T, Imai N, Kuzuya T, Yokoyama S, Yamamoto K, Ito T, Ishizu Y, Honda T, Ishigami M

    Nutrition and cancer     page: 1 - 10   2022.3

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    Language:English  

    DOI: 10.1080/01635581.2022.2049322

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  2. Patients with low muscle mass have characteristic microbiome with low potential for amino acid synthesis in chronic liver disease.

    Yamamoto K, Ishizu Y, Honda T, Ito T, Imai N, Nakamura M, Kawashima H, Kitaura Y, Ishigami M, Fujishiro M

    Scientific reports   Vol. 12 ( 1 ) page: 3674   2022.3

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    DOI: 10.1038/s41598-022-07810-3

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  3. Immune-related Liver Injury is a Poor Prognostic Factor in Patients with Nonsmall Cell Lung Cancer Treated with Immune Checkpoint Inhibitors

    Yamamoto Takafumi, Ito Takanori, Hase Tetsunari, Ishigami Masatoshi, Mizuno Kazuyuki, Yamamoto Kenta, Imai Norihiro, Ishizu Yoji, Honda Takashi, Shibata Hirofumi, Hatta Takahiro, Yogo Naoyuki, Yasuda Satoshi, Toyoda Hidenori, Abe Takashi, Kawashima Hiroki, Hashimoto Naozumi, Fujishiro Mitsuhiro

    CANCER INVESTIGATION   Vol. 40 ( 2 ) page: 189 - 198   2022.2

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  4. Absence of large portal collateral vessels is associated with spontaneous improvement of cirrhotic portal vein thrombosis

    HEPATOLOGY RESEARCH   Vol. 52 ( 2 ) page: 199 - 209   2022.2

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    Authorship:Corresponding author   Language:Japanese  

    DOI: 10.1111/hepr.13725

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  5. The influence of hepatitis C virus eradication on hepatocarcinogenesis in patients with hemophilia HCC after HCV eradication in hemophilia

    Inukai Yosuke, Imai Norihiro, Yamamoto Kenta, Ito Takanori, Ishizu Yoji, Honda Takashi, Okamoto Shuichi, Kanematsu Takeshi, Suzuki Nobuaki, Matsushita Tadashi, Ishigami Masatoshi, Fujishiro Mitsuhiro

    ANNALS OF HEPATOLOGY   Vol. 27 ( 1 ) page: 100545   2022

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  6. Assessing the Complicated Venous Hemodynamics and Therapeutic Outcomes of Budd-Chiari Syndrome with Respiratory-gated 4D Flow MR Imaging During the Expiratory and Inspiratory Phases.

    Hyodo R, Takehara Y, Mizuno T, Ichikawa K, Yokoyama S, Ishizu Y, Naganawa S

    Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine     2021.12

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    DOI: 10.2463/mrms.ici.2021-0110

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  7. Changes in the gut microbiota after hepatitis C virus eradication

    Honda Takashi, Ishigami Masatoshi, Yamamoto Kenta, Takeyama Tomoaki, Ito Takanori, Ishizu Yoji, Kuzuya Teiji, Nakamura Masanao, Kawashima Hiroki, Miyahara Ryoji, Ishikawa Tetsuya, Hirooka Yoshiki, Fujishiro Mitsuhiro

    SCIENTIFIC REPORTS   Vol. 11 ( 1 ) page: 23568   2021.12

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  8. Obesity and myosteatosis: the two characteristics of dynapenia in patients with cirrhosis. Reviewed

    Sugiyama Y, Ishizu Y, Ando Y, Yokoyama S, Yamamoto K, Ito T, Imai N, Nakamura M, Honda T, Kawashima H, Ishikawa T, Ishigami M

    European journal of gastroenterology & hepatology   Vol. 33 ( 1S Suppl 1 ) page: e916 - e921   2021.12

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1097/MEG.0000000000002303

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  9. Microbiome, fibrosis and tumor networks in a non-alcoholic steatohepatitis model of a choline-deficient high-fat diet using diethylnitrosamine

    Yamamoto Kenta, Honda Takashi, Yokoyama Shinya, Ma Lingyun, Kato Asuka, Ito Takanori, Ishizu Yoji, Kuzuya Teiji, Nakamura Masanao, Kawashima Hiroki, Ishigami Masatoshi, Tsuji Noriko M., Fujishiro Mitsuhiro

    DIGESTIVE AND LIVER DISEASE   Vol. 53 ( 11 ) page: 1443 - 1450   2021.11

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  10. Safety and Efficacy of Glass Membrane Pumping Emulsification Device in Transarterial Chemoembolization for Hepatocellular Carcinoma: First Clinical Outcomes

    Imai Norihiro, Yokoyama Shinya, Yamamoto Kenta, Ito Takanori, Ishizu Yoji, Honda Takashi, Ishigami Masatoshi

    ANTICANCER RESEARCH   Vol. 41 ( 11 ) page: 5817 - 5820   2021.11

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  11. Clinical course of liver injury induced by immune checkpoint inhibitors in patients with advanced malignancies

    Ito Takanori, Ishigami Masatoshi, Yamamoto Takafumi, Mizuno Kazuyuki, Yamamoto Kenta, Imai Norihiro, Ishizu Yoji, Honda Takashi, Kawashima Hiroki, Yasuda Satoshi, Toyoda Hidenori, Yokota Kenji, Hase Tetsunari, Nishio Naoki, Maeda Osamu, Kato Masashi, Hashimoto Naozumi, Hibi Hideharu, Kodera Yasuhiro, Sone Michihiko, Ando Yuichi, Akiyama Masashi, Shimoyama Yoshie, Fujishiro Mitsuhiro

    HEPATOLOGY INTERNATIONAL   Vol. 15 ( 5 ) page: 1278 - 1287   2021.10

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  12. Factors associated with bleeding after endoscopic variceal ligation in children

    Yokoyama Shinya, Ishizu Yoji, Ishigami Masatoshi, Honda Takashi, Kuzuya Teiji, Ito Takanori, Hinoki Akinari, Sumida Wataru, Shirota Chiyoe, Tainaka Takahisa, Makita Satoshi, Yokota Kazuki, Uchida Hiroo, Fujishiro Mitsuhiro

    PEDIATRICS INTERNATIONAL   Vol. 63 ( 10 ) page: 1223 - 1229   2021.10

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/ped.14614

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  13. USEFULNESS OF CORE I97L IN PREDICTING THE EFFICACY OF NUCLEOS(T)IDE ANALOGUE THERAPY IN PATIENTS WITH HEPATITIS B

    TakashiHonda, MasatoshiIshigami, ShinyaYokoyama, Yamamoto Kenta, Ito Takanori, Imai Norihiro, Ishizu Yoji, Ishikawa Tetsuya, Fujishiro Mitsuhiro

    HEPATOLOGY   Vol. 74   page: 468A - 469A   2021.10

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    Language:Japanese  

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  14. A PROPOSAL FOR AN APPROPRIATE METHOD OF ASSESSING FUNCTIONAL SKELETAL MUSCLE MASS USING COMPUTED TOMOGRAPHY IN PATIENTS WITH LIVER CIRRHOSIS

    Sugiyama Yoshiaki, Ishizu Yoji, Ishigami Masatoshi

    HEPATOLOGY   Vol. 74   page: 1203A - 1203A   2021.10

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  15. Conditioned medium from stem cells derived from human exfoliated deciduous teeth ameliorates NASH via the Gut-Liver axis

    Muto Hisanori, Ito Takanori, Tanaka Taku, Yokoyama Shinya, Yamamoto Kenta, Imai Norihiro, Ishizu Yoji, Maeda Keiko, Honda Takashi, Ishikawa Tetsuya, Kato Asuka, Ohshiro Taichi, Kano Fumiya, Yamamoto Akihito, Sakai Kiyoshi, Hibi Hideharu, Ishigami Masatoshi, Fujishiro Mitsuhiro

    SCIENTIFIC REPORTS   Vol. 11 ( 1 ) page: 18778   2021.9

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  16. Revisiting Prognosis After Liver Transplant in Patients Positive for Hepatitis C Virus: Focus on Hepatitis C Recurrence-Unrelated Complications

    Ishigami Masatoshi, Honda Takashi, Ishizu Yoji, Imai Norihiro, Ito Takanori, Yamamoto Kenta, Kamei Hideya, Ogura Yasuhiro, Fujishiro Mitsuhiro

    EXPERIMENTAL AND CLINICAL TRANSPLANTATION   Vol. 19 ( 9 ) page: 935 - 942   2021.9

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  17. Transient deterioration of albumin-bilirubin scores in early post-dose period of molecular targeted therapies in advanced hepatocellular carcinoma with 50% or higher liver occupation A STROBE-compliant retrospective observational study

    Muto Hisanori, Kuzuya Teiji, Ito Takanori, Ishizu Yoji, Honda Takashi, Ishikawa Tetsuya, Ishigami Masatoshi, Fujishiro Mitsuhiro

    MEDICINE   Vol. 100 ( 31 ) page: e26820   2021.8

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  18. Quality of Life in patients with nonalcoholic fatty liver disease: Structure and related factors focusing on illness uncertainty

    Ozawa Naoki, Sato Kazuki, Sugimura Ayumi, Maki Shigeyoshi, Tanaka Taku, Yamamoto Kenta, Ito Takanori, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Ishigami Masatoshi, Fujishiro Mitsuhiro, Ishikawa Tetsuya, Ando Shoko

    JAPAN JOURNAL OF NURSING SCIENCE   Vol. 18 ( 3 ) page: e12415   2021.7

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  19. The impact of hepatitis C virus eradication on hepatocarcinogenesis in haemophiliacs

    Inukai Yosuke, Imai Norihiro, Yamamoto Kenta, Ito Takanori, Ishizu Yoji, Honda Takashi, Ishigami Masatoshi

    JOURNAL OF HEPATOLOGY   Vol. 75   page: S787 - S788   2021.7

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  20. Tolerability of Molecular-targeted Agents for Hepatocellular Carcinoma Treatment in Haemophiliacs

    Yamamoto Takafumi, Imai Norihiro, Yamamoto Kenta, Ito Takanori, Ishizu Yoji, Honda Takashi, Okamoto Shuichi, Kanematsu Takeshi, Suzuki Nobuaki, Matsushita Tadashi, Ishigami Masatoshi, Fujishiro Mitsuhiro

    ANTICANCER RESEARCH   Vol. 41 ( 5 ) page: 2569 - 2573   2021.5

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  21. Impact of visceral fat accumulation on the prognosis of patients with cirrhosis Reviewed

    Ishizu Yoji, Ishigami Masatoshi, Honda Takashi, Imai Norihiro, Ito Takanori, Yamamoto Kenta, Fujishiro Mitsuhiro

    CLINICAL NUTRITION ESPEN   Vol. 42   page: 354 - 360   2021.4

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.clnesp.2021.01.008

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  22. Time-resolved 3D cine phase-contrast magnetic resonance imaging (4D-flow MRI) can quantitatively assess portosystemic shunt severity and confirm normalization of portal flow after embolization of large portosystemic shunts Reviewed

    Hyodo Ryota, Takehara Yasuo, Mizuno Takashi, Ichikawa Kazushige, Ishizu Yoji, Sugiyama Masataka, Naganawa Shinji

    HEPATOLOGY RESEARCH   Vol. 51 ( 3 ) page: 343 - 349   2021.3

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/hepr.13616

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  23. The relationship between oral-origin bacteria in the fecal microbiome and albumin-bilirubin grade in patients with hepatitis C Reviewed

    Yamamoto Kenta, Honda Takashi, Ito Takanori, Ishizu Yoji, Kuzuya Teiji, Nakamura Masanao, Miyahara Ryoji, Kawashima Hiroki, Ishigami Masatoshi, Fujishiro Mitsuhiro

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 36 ( 3 ) page: 790 - 799   2021.3

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/jgh.15206

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  24. Simplification of balloon-occluded retrograde transcatheter obliteration procedure using a coaxial double balloon catheter compared with a single-balloon catheter Reviewed

    Ishizu Yoji, Ishigami Masatoshi, Honda Takashi, Kuzuya Teiji, Ito Takanori, Komada Tomohiro, Fujishiro Mitsuhiro

    JAPANESE JOURNAL OF RADIOLOGY   Vol. 39 ( 3 ) page: 296 - 302   2021.3

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s11604-020-01060-x

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  25. Safety and efficacy of percutaneous radiofrequency ablation for hepatocellular carcinoma patients with haemophilia Reviewed

    Yamamoto Takafumi, Imai Norihiro, Yamamoto Kenta, Ito Takanori, Ishizu Yoji, Honda Takashi, Okamoto Shuichi, Kanematsu Takeshi, Suzuki Nobuaki, Matsushita Tadashi, Ishigami Masatoshi, Fujishiro Mitsuhiro

    HAEMOPHILIA   Vol. 27 ( 1 ) page: 100 - 107   2021.1

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/hae.14220

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  26. Progression After Molecular Targeted Agents: Hepatic Arterial Changes and Transarterial Chemoembolization in Hepatocellular Carcinoma

    Matsuda Noritaka, Imai Norihiro, Kuzuya Teiji, Yamamoto Kenta, Ito Takanori, Ishizu Yoji, Honda Takashi, Ishigami Masatoshi, Fujishiro Mitsuhiro

    IN VIVO   Vol. 35 ( 2 ) page: 1185 - 1189   2021

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  27. Amino Acid Polymorphism in Hepatitis B Virus Associated With Functional Cure

    Honda Takashi, Yamada Norie, Murayama Asako, Shiina Masaaki, Aly Hussein Hassan, Kato Asuka, Ito Takanori, Ishizu Yoji, Kuzuya Teiji, Ishigami Masatoshi, Murakami Yoshiki, Tanaka Tomohisa, Moriishi Kohji, Nishitsuji Hironori, Shimotohno Kunitada, Ishikawa Tetsuya, Fujishiro Mitsuhiro, Muramatsu Masamichi, Wakita Takaji, Kato Takanobu

    CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY   Vol. 12 ( 5 ) page: 1583 - 1598   2021

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  28. AMINO ACID POLYMORPHISM IN HEPATITIS B VIRUS ASSOCIATED WITH NATURAL CLEARANCE OF HBV DNA AND HBsAg

    Honda Takashi, Yamada None, Murayama Asako, Kato Asuka, Ito Takanori, Ishizu Yoji, Kuzuya Teiji, Ishigami Masatoshi, Murakami Yoshiki, Ishikawa Tetsuya, Fujishiro Mitsuhiro, Kato Takanobu

    HEPATOLOGY   Vol. 72   page: 508A - 509A   2020.11

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  29. IMPROVEMENT OF LIVER FUNCTIONAL RESERVE AFTER SVR IN HCV-PATIENTS WITH COMPENSATED, SEVERE FIBROSIS BY IFN-FREE, DAA COMBINATION TREATMENT-IMPACT OF PRETREATMENT SERUM AFP LEVELS

    Ishigami Masatoshi, Honda Takashi, Ishizu Yoji, Imai Norihiro, Ito Takanori, Yamamoto Kenta, Fujishiro Mitsuhiro

    HEPATOLOGY   Vol. 72   page: 564A - 565A   2020.11

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  30. GUT MICROBIOTA ASSOCIATED WITH THE DIFFERENCE BETWEEN PATIENTS WITH AND WITHOUT HEPATOCELLULAR CARCINOMA IN CHRONIC LIVER DISEASE

    Honda Takashi, Ishigami Masatoshi, Yamamoto Kenta, Ito Takanori, Imai Norihiro, Ishizu Yoji, Fujishiro Mitsuhiro

    HEPATOLOGY   Vol. 72   page: 370A - 370A   2020.11

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  31. The albumin-bilirubin score as a predictor of outcomes in Japanese patients with PBC: an analysis using time-dependent ROC Reviewed

    Ito Takanori, Ishigami Masatoshi, Morooka Hikaru, Yamamoto Kenta, Imai Norihiro, Ishizu Yoji, Honda Takashi, Nishimura Daisaku, Tada Toshifumi, Yasuda Satoshi, Toyoda Hidenori, Kumada Takashi, Fujishiro Mitsuhiro

    SCIENTIFIC REPORTS   Vol. 10 ( 1 ) page: 17812   2020.10

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    DOI: 10.1038/s41598-020-74732-3

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  32. Efficacy and Safety of Sorafenib in Unresectable Hepatocellular Carcinoma with Bile Duct Invasion. Reviewed

    Tanaka T, Kuzuya T, Ishigami M, Ito T, Ishizu Y, Honda T, Ishikawa T, Fujishiro M

    Oncology   Vol. 98 ( 9 ) page: 621 - 629   2020.9

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1159/000507051

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  33. Revisiting the indications for liver transplantation in cirrhotic patients considering the long-term outcomes of cirrhotic patients

    Ishigami Masatoshi, Honda Takashi, Kuzuya Teiji, Ishizu Yoji, Ito Takanori, Kamei Hideya, Ogura Yasuhiro, Fujishiro Mitsuhiro

    JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES   Vol. 27 ( 9 ) page: 655 - 662   2020.9

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/jhbp.777

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  34. Limitation of non-transplant treatment and proper timing for liver transplantation in patients with hepatocellular carcinoma considering long-term survival. Reviewed

    Nomura A, Ishigami M, Honda T, Kuzuya T, Ishizu Y, Ito T, Kamei H, Onishi Y, Ogura Y, Fujishiro M

    Medicine   Vol. 99 ( 28 ) page: e21161   2020.7

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1097/MD.0000000000021161

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  35. Serum Nutritional Markers as Prognostic Factors for Hepatic and Extrahepatic Carcinogenesis in Japanese Patients with Nonalcoholic Fatty Liver Disease Reviewed

    Ito Takanori, Ishigami Masatoshi, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Ishikawa Tetsuya, Toyoda Hidenori, Kumada Takashi, Fujishiro Mitsuhiro

    NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL   Vol. 72 ( 5 ) page: 884 - 891   2020.7

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    DOI: 10.1080/01635581.2019.1653474

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  36. Correlation of serum zinc levels with pathological and laboratory findings in patients with nonalcoholic fatty liver disease Reviewed

    Ito Takanori, Ishigami Masatoshi, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Ishikawa Tetsuya, Toyoda Hidenori, Kumada Takashi, Fujishiro Mitsuhiro

    EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY   Vol. 32 ( 6 ) page: 748 - 753   2020.6

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1097/MEG.0000000000001587

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  37. Complete response of advanced hepatocellular carcinoma achieved by sorafenib dose re-escalation after failure of long-term low-dose-sorafenib treatment combined with transcatheter arterial chemoembolization: a case report Reviewed

    Muto Hisanori, Kuzuya Teiji, Ito Takanori, Ishizu Yoji, Honda Takashi, Ishikawa Tetsuya, Ishigami Masatoshi, Fujishiro Mitsuhiro

    CLINICAL JOURNAL OF GASTROENTEROLOGY   Vol. 13 ( 3 ) page: 397 - 402   2020.6

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    DOI: 10.1007/s12328-019-01066-7

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  38. Real world data of liver injury induced by immune checkpoint inhibitors in Japanese patients with advanced malignancies Reviewed

    Mizuno Kazuyuki, Ito Takanori, Ishigami Masatoshi, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Kawashima Hiroki, Inukai Yosuke, Toyoda Hidenori, Yokota Kenji, Hase Tetsunari, Maeda Osamu, Kiyoi Hitoshi, Nagino Masato, Hibi Hideharu, Kodera Yasuhiro, Fujimoto Yasushi, Sone Michihiko, Gotoh Momokazu, Ando Yuichi, Akiyama Masashi, Hasegawa Yoshinori, Fujishiro Mitsuhiro

    JOURNAL OF GASTROENTEROLOGY   Vol. 55 ( 6 ) page: 653 - 661   2020.6

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    DOI: 10.1007/s00535-020-01677-9

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  39. Initial Experience of Ramucirumab Treatment After Lenvatinib Failure for Patients With Advanced Hepatocellular Carcinoma

    Kuzuya Teiji, Ishigami Masatoshi, Ito Takanori, Ishizu Yoji, Honda Takashi, Ishikawa Tetsuya, Fujishiro Mitsuhiro

    ANTICANCER RESEARCH   Vol. 40 ( 4 ) page: 2089 - 2093   2020.4

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    DOI: 10.21873/anticanres.14167

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  40. Sorafenib vs. Lenvatinib as First-line Therapy for Advanced Hepatocellular Carcinoma With Portal Vein Tumor Thrombosis Reviewed

    Kuzuya Teiji, Ishigami Masatoshi, Ito Takanori, Ishizu Yoji, Honda Takashi, Ishikawa Tetsuya, Fujishiro Mitsuhiro

    ANTICANCER RESEARCH   Vol. 40 ( 4 ) page: 2283 - 2290   2020.4

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    DOI: 10.21873/anticanres.14193

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  41. Favorable radiological antitumor response at 2 weeks after starting lenvatinib for patients with advanced hepatocellular carcinoma Reviewed

    Kuzuya Teiji, Ishigami Masatoshi, Ito Takanori, Ishizu Yoji, Honda Takashi, Ishikawa Tetsuya, Fujishiro Mitsuhiro

    HEPATOLOGY RESEARCH   Vol. 50 ( 3 ) page: 374 - 381   2020.3

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/hepr.13452

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  42. Relationship Between Adverse Events and Microbiomes in Advanced Hepatocellular Carcinoma Patients Treated With Sorafenib

    Yamamoto Kenta, Kuzuya Teiji, Honda Takashi, Ito Takanori, Ishizu Yoji, Nakamura Masanao, Miyahara Ryoji, Kawashima Hiroki, Ishigami Masatoshi, Fujishiro Mitsuhiro

    ANTICANCER RESEARCH   Vol. 40 ( 2 ) page: 665 - 676   2020.2

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    DOI: 10.21873/anticanres.13996

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  43. Effect of weight change and lifestyle modifications on the development or remission of nonalcoholic fatty liver disease: sex-specific analysis. Reviewed

    Yoshioka N, Ishigami M, Watanabe Y, Sumi H, Doisaki M, Yamaguchi T, Ito T, Ishizu Y, Kuzuya T, Honda T, Ishikawa T, Haruta JI, Fujishiro M

    Scientific reports   Vol. 10 ( 1 ) page: 481   2020.1

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    DOI: 10.1038/s41598-019-57369-9

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  44. Rapid increase of platelet counts during antiviral therapy in patients with hepatitis C virus infection Reviewed

    Ishizu Yoji, Ishigami Masatoshi, Hayashi Kazuhiko, Honda Takashi, Kuzuya Teiji, Ito Takanori, Fujishiro Mitsuhiro

    HEPATOLOGY RESEARCH   Vol. 50 ( 1 ) page: 47 - 56   2020.1

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/hepr.13426

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  45. Sarcopenia impairs health-related quality of life in cirrhotic patients

    Ando Yusuke, Ishigami Masatoshi, Ito Takanori, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Ishikawa Tetsuya, Fujishiro Mitsuhiro

    EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY   Vol. 31 ( 12 ) page: 1550 - 1556   2019.12

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1097/MEG.0000000000001472

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  46. Feasibility and usefulness of endoscopic ultrasonography-guided shear-wave measurement for assessment of autoimmune pancreatitis activity: a prospective exploratory study

    Ohno Eizaburo, Hirooka Yoshiki, Kawashima Hiroki, Ishikawa Takuya, Tanaka Hiroyuki, Sakai Daisuke, Ishizu Yoji, Kuzuya Teiji, Nakamura Masanao, Honda Takashi

    JOURNAL OF MEDICAL ULTRASONICS   Vol. 46 ( 4 ) page: 425 - 433   2019.10

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    DOI: 10.1007/s10396-019-00944-4

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  47. CHANGES OF MICROBIOTA AFTER HEPATITIS C VIRUS ERADICATION

    Honda Takashi, Ishigami Masatoshi, Yamamoto Kenta, Ito Takanori, Ishizu Yoji, Kuzuya Teiji, Fujishiro Mitsuhiro

    HEPATOLOGY   Vol. 70   page: 1160A - 1161A   2019.10

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  48. INDICATION FOR HCC TREATMENT IN RECENT ERA-PROPOSAL OF THE NEW PRIORITY FOR LIVER TRANSPLANTATION IN PATIENTS WITH HCC

    Ishigami Masatoshi, Honda Takashi, Kuzuya Teiji, Ishizu Yoji, Ito Takanori, Fujishiro Mitsuhiro

    HEPATOLOGY   Vol. 70   page: 543A - 544A   2019.10

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  49. UTILITY OF THE ALBUMIN-BILIRUBIN SCORE FOR PREDICTING PROGNOSIS IN JAPANESE PATIENTS WITH PRIMARY BILIARY CHOLANGITIS: AN ANALYSIS USING TIME-DEPENDENT RECEIVER OPERATING CHARACTERISTICS

    Ito Takanori, Ishigami Masatoshi, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Yasuda Satoshi, Toyoda Hidenori, Kumada Takashi, Fujishiro Mitsuhiro

    HEPATOLOGY   Vol. 70   page: 789A - 790A   2019.10

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  50. Spleen stiffness by 2-D shear wave elastography is the most accurate predictor of high-risk esophagogastric varices in children with biliary atresia

    Yokoyama Shinya, Ishigami Masatoshi, Honda Takashi, Kuzuya Teiji, Ishizu Yoji, Ito Takanori, Hirooka Yoshiki, Tanaka Yujiro, Tainaka Takahisa, Shirota Chiyoe, Chiba Kosuke, Uchida Hiroo, Fujishiro Mitsuhiro

    HEPATOLOGY RESEARCH   Vol. 49 ( 10 ) page: 1162 - 1168   2019.10

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/hepr.13381

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  51. NON-INVASIVE SCREENING FOR DETECTING ESOPHAGOGASTRIC VARICES IN CHILDREN WITH BILIARY ATRESIA

    Yokoyama Shinya, Ishigami Masatoshi, Honda Takashi, Kuzuya Teiji, Ishizu Yoji, Ito Takanori, Shirota Chiyoe, Uchida Hiroo, Fujishiro Mitsuhiro

    HEPATOLOGY   Vol. 70   page: 200A - 200A   2019.10

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  52. Clinical characteristics and outcomes of candidates for second-line therapy, including regorafenib and ramucirumab, for advanced hepatocellular carcinoma after sorafenib treatment

    Kuzuya Teiji, Ishigami Masatoshi, Ito Takanori, Ishizu Yoji, Honda Takashi, Ishikawa Tetsuya, Hirooka Yoshiki, Fujishiro Mitsuhiro

    HEPATOLOGY RESEARCH   Vol. 49 ( 9 ) page: 1054 - 1065   2019.9

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    DOI: 10.1111/hepr.13358

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  53. Antifibrotic Effects of 1,25(OH)(2)D-3 on Nonalcoholic Steatohepatitis in Female Mice

    Ma Lingyun, Ishigami Masatoshi, Honda Takashi, Yokoyama Shinya, Yamamoto Kenta, Ishizu Yoji, Kuzuya Teiji, Hayashi Kazuhiko, Hirooka Yoshiki, Goto Hidemi

    DIGESTIVE DISEASES AND SCIENCES   Vol. 64 ( 9 ) page: 2581 - 2590   2019.9

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    DOI: 10.1007/s10620-019-05560-3

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  54. The relationship between portal hypertension and the microbiome

    Yamamoto K., Honda T., Hattori S., Pu L. Zorron Cheng Tao, Ito T., Yamamura T., Ishizu Y., Kuzuya T., Ishigami M., Fujishiro M.

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 34   page: 106 - 107   2019.9

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  55. Association between core mutations and annual decline rate of HBVDNA and HBsAg in chronic hepatitis B patients treated with nucleoside analogue

    Honda Takashi, Ishigami Masatoshi, Ito Takanori, Ishizu Yoji, Kuzuya Teiji, Fujishiro Mitsuhiro

    JOURNAL OF HEPATOLOGY   Vol. 70 ( 1 ) page: E258 - E258   2019.4

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  56. Association between gut microbiota and hepatocellular carcinoma in patients with chronic liver disease

    Honda Takashi, Ishigami Masatoshi, Yamamoto Kenta, Ito Takanori, Ishizu Yoji, Kuzuya Teiji, Fujishiro Mitsuhiro

    JOURNAL OF HEPATOLOGY   Vol. 70 ( 1 ) page: E512 - E513   2019.4

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  57. Serum Zinc levels as a prognostic factor for extra-hepatic carcinogenesis in Japanese patients with non-alcoholic liver disease

    Ito Takanori, Ishigami Masatoshi, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Fujishiro Mitsuhiro

    JOURNAL OF HEPATOLOGY   Vol. 70 ( 1 ) page: E298 - E298   2019.4

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  58. The optimal cut-off points of FIB-4 index for predicting the incidences of HCC and extra-hepatic malignancies in biopsyproven Japanese NAFLD patients

    Ito Takanori, Ishigami Masatoshi, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Fujishiro Mitsuhiro

    JOURNAL OF HEPATOLOGY   Vol. 70 ( 1 ) page: E775 - E775   2019.4

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  59. The early clinical response at 2 weeks of lenvatinib therapy for patients with advanced HCC

    Kuzuya Teiji, Ishigami Masatoshi, Ito Takanori, Ishizu Yoji, Honda Takashi, Fujishiro Mitsuhiro

    JOURNAL OF HEPATOLOGY   Vol. 70 ( 1 ) page: E611 - E611   2019.4

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  60. Complete response by vitamin K2 analog monotherapy in sorafenib-failure advanced hepatocellular carcinoma: A case report

    Kuzuya Teiji, Ishigami Masatoshi, Ishizu Yoji, Honda Takashi, Hayashi Kazuhiko, Ishikawa Tetsuya, Hirooka Yoshiki, Goto Hidemi

    HEPATOLOGY RESEARCH   Vol. 49 ( 3 ) page: 360 - 364   2019.3

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    DOI: 10.1111/hepr.13237

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  61. Influence of proton pump inhibitors on microbiota in chronic liver disease patients

    Yamamoto Kenta, Ishigami Masatoshi, Honda Takashi, Takeyama Tomoaki, Ito Takanori, Ishizu Yoji, Kuzuya Teiji, Hayashi Kazuhiko, Goto Hidemi, Hirooka Yoshiki

    HEPATOLOGY INTERNATIONAL   Vol. 13 ( 2 ) page: 234 - 244   2019.3

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    DOI: 10.1007/s12072-019-09932-9

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  62. Utility and limitations of noninvasive fibrosis markers for predicting prognosis in biopsy-proven Japanese non-alcoholic fatty liver disease patients.

    Ito T, Ishigami M, Ishizu Y, Kuzuya T, Honda T, Hayashi K, Nishimura D, Toyoda H, Kumada T, Goto H, Hirooka Y

    Journal of gastroenterology and hepatology   Vol. 34 ( 1 ) page: 207-214   2019.1

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    DOI: 10.1111/jgh.14448

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  63. Successful Treatment of Hepatocellular Carcinoma with Regorafenib after Sorafenib-induced Hypersensitivity

    Yoshioka Naoki, Kuzuya Teiji, Ito Takanori, Ishizu Yoji, Honda Takashi, Ishikawa Tetsuya, Ishigami Masatoshi, Fujishiro Mitsuhiro

    INTERNAL MEDICINE   Vol. 58 ( 19 ) page: 2803 - 2808   2019

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    DOI: 10.2169/internalmedicine.2812-19

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  64. The Prevalence of Mixed Hepatitis C Virus Genotype Infection and Its Effect on the Response to Direct-Acting Antivirals Therapy

    Hayashi Kazuhiko, Tachi Kosuke, Shimizu Yuko, Nagano Kenichi, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Ishigami Masatoshi, Hirooka Yoshiki, Hattori Masashi, Goto Hidemi

    INTERVIROLOGY   Vol. 62 ( 1 ) page: 23 - 29   2019

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    DOI: 10.1159/000499691

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  65. Utility of contrast-enhanced ultrasonography with perflubutane in evaluating indications for diagnostic percutaneous tumor biopsy in a case of hepatic sclerosed hemangioma

    Ando Yusuke, Ishigami Masatoshi, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Hirooka Yoshiki

    CLINICAL JOURNAL OF GASTROENTEROLOGY   Vol. 11 ( 6 ) page: 514 - 520   2018.12

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    DOI: 10.1007/s12328-018-0880-2

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  66. Late relapse of hepatitis C virus in patients with sustained virological response after daclatasvir and asunaprevir therapy

    Hayashi Kazuhiko, Ishigami Masatoshi, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Hirooka Yoshiki, Toyoda Hidenori, Kumada Takashi, Hattori Masashi, Katano Yoshiaki, Goto Hidemi

    JOURNAL OF VIRAL HEPATITIS   Vol. 25 ( 12 ) page: 1446 - 1451   2018.12

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    DOI: 10.1111/jvh.12967

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  67. Substitutions in interferon sensitivity-determining region and hepatocarcinogenesis after hepatitis C virus eradication

    Yasuda Satoshi, Ishigami Masatoshi, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Hayashi Kazuhiko, Toyoda Hidenori, Kumada Takashi, Hirooka Yoshiki, Goto Hidemi

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 33 ( 11 ) page: 1904 - 1911   2018.11

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    DOI: 10.1111/jgh.14280

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  68. Skeletal muscle fat deposition is associated with hepatocellular carcinoma development in patients with chronic liver disease

    Tachi Yoshihiko, Kozuka Akihiro, Hirai Takanori, Kojima Yuko, Ishizu Yoji, Honda Takashi, Kuzuya Teiji, Hayashi Kazuhiko, Ishigami Masatoshi, Goto Hidemi

    NUTRITION   Vol. 54   page: 83 - 88   2018.10

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    DOI: 10.1016/j.nut.2018.03.011

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  69. Association between Core Mutations Induced By Interferon Therapy and Annual Decline Rate of Hbvdna in Chronic Hepatitis B Patients

    Honda Takashi, Ishigami Masatoshi, Ito Takanori, Ishizu Yoji, Kuzuya Teiji, Hirooka Yoshiki

    HEPATOLOGY   Vol. 68   page: 1233A-1234A   2018.10

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  70. Comparison of Gut Microbiota and Predicted Functional Metagenome in Hepatitis C Patients with and without Advanced Fibrosis Categorized By FIB4-Index

    Yamamoto Kenta, Ishigami Masatoshi, Ito Takanori, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Hirooka Yoshiki

    HEPATOLOGY   Vol. 68   page: 590A-590A   2018.10

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  71. Interferon-Free Antiviral Therapy Rapidly Improves Thrombocytopenia in Patients with Advanced Chronic Hepatitis C

    Ishizu Yoji, Ishigami Masatoshi, Ito Takanori, Kuzuya Teiji, Honda Takashi, Hirooka Yoshiki

    HEPATOLOGY   Vol. 68   page: 1157A-1158A   2018.10

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  72. Late Relapse and Molecular Analysis of Hepatitis C Virus in Patients with Sustained Virological Response By All Oral Direct Acting Antivirals Therapy

    Hayashi Kazuhiko, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Ishigami Masatoshi, Shimizu Yuko, Tachi Kousuke, Goto Hidemi

    HEPATOLOGY   Vol. 68   page: 927A-927A   2018.10

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  73. Predictive ability of shear wave elastography for pruritus in chronic hepatitis C patients with sustained virological response

    Tachi Yoshihiko, Hirai Takanori, Kojima Yuko, Ishizu Yoji, Honda Takashi, Kuzuya Teiji, Hayashi Kazuhiko, Ishigami Masatoshi, Goto Hidemi, Katano Yoshiaki

    EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY   Vol. 30 ( 9 ) page: 1066 - 1072   2018.9

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    DOI: 10.1097/MEG.0000000000001159

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  74. Impact of myosteatosis on skeletal muscle volume loss in patients with chronic liver disease

    Tachi Yoshihiko, Kozuka Akihiro, Hirai Takanori, Ishizu Yoji, Honda Takashi, Kuzuya Teiji, Hayashi Kazuhiko, Ishigami Masatoshi, Goto Hidemi

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 33 ( 9 ) page: 1659 - 1666   2018.9

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    DOI: 10.1111/jgh.14133

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  75. Successful treatment of esophageal bleeding due to rupture of major aortopulmonary collateral arteries by transcatheter arterial embolization.

    Ito T, Ishigami M, Ishizu Y, Kuzuya T, Honda T, Matsushima M, Kato T, Hirooka Y

    Clinical journal of gastroenterology     2018.8

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    DOI: 10.1007/s12328-018-0895-8

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  76. Diagnostic Usefulness of APRI and FIB-4 for the Prediction of Liver Fibrosis After Liver Transplantation in Patients Infected with Hepatitis C Virus

    Imai H., Kamei H., Onishi Y., Ishizu Y., Ishigami M., Goto H., Ogura Y.

    TRANSPLANTATION PROCEEDINGS   Vol. 50 ( 5 ) page: 1431-1436   2018.6

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    DOI: 10.1016/j.transproceed.2018.03.005

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  77. Daclatasvir and asunaprevir treatment in patients infected by genotype 1b of hepatitis C virus with no or subtle resistant associated substitutions (RAS) in NS5A-Y93

    Ishigami Masatoshi, Hayashi Kazuhiko, Honda Takashi, Kuzuya Teiji, Ishizu Yoji, Ishikawa Tetsuya, Nakano Isao, Urano Fumihiro, Kumada Takashi, Yoshioka Kentaro, Hirooka Yoshiki, Goto Hidemi

    JOURNAL OF MEDICAL VIROLOGY   Vol. 90 ( 4 ) page: 736 - 744   2018.4

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    DOI: 10.1002/jmv.24978

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  78. Naturally occurring drug resitance substitutions in the NS5A and NS5B regions in Hepatitis C virus genotype 2 and response to sofosbuvir plus ribavirin therapy

    Hayashi K., Ishigami M., Ishizu Y., Kazuya T., Honda T., Hirooka Y., Goto H.

    JOURNAL OF HEPATOLOGY   Vol. 68   page: S297-S297   2018.4

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  79. Utility and limitation of non-invasive fibrosis markers for predicting the prognosis in biopsy-proven Japanese NAFLD patients

    Ito T., Ishigami M., Ishizu Y., Kazuya T., Honda T., Hayashi K., Ishikawa T., Hirooka Y., Goto H.

    JOURNAL OF HEPATOLOGY   Vol. 68   page: S561-S561   2018.4

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  80. Secreted ectodomain of SIGLEC-9 and MCP-1 ameliorate acute liver failure in rats by altering bone marrow macrophage polarity

    Ito T., Ishigami M., Yamamoto A., Ishizu Y., Kazuya T., Honda T., Hayashi K., Ishikawa T., Hirooka Y., Goto H.

    JOURNAL OF HEPATOLOGY   Vol. 68   page: S614-S614   2018.4

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  81. Cumulative incidence and risk factors for the development of hepatocellular carcinoma in patients with chronic hepatitis B who achieved sustained disappearance of viremia by nucleos(t)ide analog treatment

    Ando Yusuke, Ishigami Masatoshi, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Hayashi Kazuhiko, Ishikawa Tetsuya, Nakano Isao, Hirooka Yoshiki, Goto Hidemi

    HEPATOLOGY RESEARCH   Vol. 48 ( 3 ) page: E240 - E251   2018.2

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    DOI: 10.1111/hepr.12976

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  82. Occurrence of late relapse of hepatitis C virus confirmed by molecular analysis after sustained virologic response to interferon-ribavirin-based therapy

    Hayashi Kazuhiko, Ishigami Masatoshi, Yasuda Satoshi, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Ishikawa Tetsuya, Hirooka Yoshiki, Goto Hidemi

    HEPATOLOGY RESEARCH   Vol. 48 ( 3 ) page: E78 - E86   2018.2

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    DOI: 10.1111/hepr.12929

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  83. Comparison of direct sequencing and Invader assay for Y93H mutation and response to interferon-free therapy in hepatitis C virus genotype 1b

    Hayashi Kazuhiko, Ishigami Masatoshi, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Kawashima Hiroki, Ishikawa Tetsuya, Tachi Yoshihiko, Hattori Masashi, Katano Yoshiaki, Goto Hidemi, Hirooka Yoshiki

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 33 ( 1 ) page: 249 - 255   2018.1

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    DOI: 10.1111/jgh.13809

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  84. Liver stiffness reduction correlates with histological characteristics of hepatitis C patients with sustained virological response

    Tachi Yoshihiko, Hirai Takanori, Kojima Yuko, Ishizu Yoji, Honda Takashi, Kuzuya Teiji, Hayashi Kazuhiko, Ishigami Masatoshi, Goto Hidemi

    LIVER INTERNATIONAL   Vol. 38 ( 1 ) page: 59 - 67   2018.1

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    DOI: 10.1111/liv.13486

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  85. Prognostic Factors Associated with Postprogression Survival in Advanced Hepatocellular Carcinoma Patients Treated with Sorafenib Not Eligible for Second-Line Regorafenib Treatment

    Kuzuya Teiji, Ishigami Masatoshi, Ishizu Yoji, Honda Takashi, Hayashi Kazuhiko, Ishikawa Tetsuya, Nakano Isao, Hirooka Yoshiki, Goto Hidemi

    ONCOLOGY   Vol. 95 ( 2 ) page: 91 - 99   2018

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    DOI: 10.1159/000488453

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  86. Daclatasvir and asunaprevir treatment in patients with severe liver fibrosis by hepatitis C virus genotype 1b infection: Real-world data

    Ishigami Masatoshi, Hayashi Kazuhiko, Honda Takashi, Kuzuya Teiji, Ishizu Yoji, Ishikawa Tetsuya, Nakano Isao, Urano Fumihiro, Kumada Takashi, Yoshioka Kentaro, Goto Hidemi, Hirooka Yoshiki

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 32 ( 11 ) page: 1879 - 1886   2017.11

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    DOI: 10.1111/jgh.13779

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  87. Low skeletal muscle mass predicts early mortality in cirrhotic patients with acute variceal bleeding

    Ishizu Yoji, Ishigami Masatoshi, Kuzuya Teiji, Honda Takashi, Hayashi Kazuhiko, Ishikawa Tetsuya, Hirooka Yoshiki, Goto Hidemi

    NUTRITION   Vol. 42   page: 87 - 91   2017.10

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    DOI: 10.1016/j.nut.2017.06.004

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  88. Hepatocyte-specific depletion of ubiquitin regulatory X domain containing protein 8 accelerates fibrosis in a mouse non-alcoholic steatohepatitis model

    Imai Norihiro, Suzuki Michitaka, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Hayashi Kazuhiko, Ishigami Masatoshi, Hirooka Yoshiki, Ishikawa Tetsuya, Goto Hidemi, Fujimoto Toyoshi

    HISTOCHEMISTRY AND CELL BIOLOGY   Vol. 148 ( 3 ) page: 219 - 227   2017.9

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    DOI: 10.1007/s00418-017-1572-6

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  89. Liver stiffness measurement predicts hepatocellular carcinoma development in patients treated with direct-acting antivirals

    Tachi Yoshihiko, Hirai Takanori, Kojima Yuko, Ishizu Yoji, Honda Takashi, Kuzuya Teiji, Hayashi Kazuhiko, Ishigami Masatoshi, Goto Hidemi

    JGH OPEN   Vol. 1 ( 1 ) page: 44 - 49   2017.9

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    DOI: 10.1002/jgh3.12007

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  90. Utility of Doppler ultrasonography for diagnosing and assessing treatment effects in liver compartment syndrome

    Ando Yusuke, Ishigami Masatoshi, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Hayashi Kazuhiko, Ishikawa Tetsuya, Goto Hidemi, Hirooka Yoshiki

    CLINICAL JOURNAL OF GASTROENTEROLOGY   Vol. 10 ( 3 ) page: 265 - 269   2017.6

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    DOI: 10.1007/s12328-017-0741-4

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  91. Core I97L mutation in conjunction with P79Q is associated with persistent low HBV DNA and HBs antigen clearance in patients with chronic hepatitis B

    Honda T., Ishigami M., Ishizu Y., Kuzuya T., Hayashi K., Ishikawa T., Murakami Y., Iwadate M., Umeyama H., Toyoda H., Kumada T., Katano Y., Goto H., Hirooka Y.

    CLINICAL MICROBIOLOGY AND INFECTION   Vol. 23 ( 6 )   2017.6

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    DOI: 10.1016/j.cmi.2016.12.014

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  92. Real World Data of Daclatasvir and Asunaprevir Combination Therapy for HCV Genotype 1b Infection in Patients With Renal Dysfunction

    Ishigami Masatoshi, Hayashi Kazuhiko, Honda Takashi, Kuzuya Teiji, Ishizu Yoji, Ishikawa Tetsuya, Nakano Isao, Urano Fumihiro, Kumada Takashi, Yoshioka Kentaro, Goto Hidemi, Hirooka Yoshiki

    CLINICAL GASTROENTEROLOGY AND HEPATOLOGY   Vol. 15 ( 5 ) page: 787 - 788   2017.5

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    DOI: 10.1016/j.cgh.2016.12.009

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  93. Branched-chain amino acids alleviate hepatic steatosis and liver injury in choline-deficient high-fat diet induced NASH mice

    Honda Takashi, Ishigami Masatoshi, Luo Fangqiong, Lingyun Ma, Ishizu Yoji, Kuzuya Teiji, Hayashi Kazuhiko, Nakano Isao, Ishikawa Tetsuya, Feng Guo-Gang, Katano Yoshiaki, Kohama Tomoya, Kitaura Yasuyuki, Shimomura Yoshiharu, Goto Hidemi, Hirooka Yoshiki

    METABOLISM-CLINICAL AND EXPERIMENTAL   Vol. 69   page: 177 - 187   2017.4

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    DOI: 10.1016/j.metabol.2016.12.013

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  94. Immunoglobulin G4-associated autoimmune hepatitis later complicated by autoimmune pancreatitis: A case report Reviewed

    Yoji Ishizu, Masatoshi Ishigami, Teiji Kuzuya, Takashi Honda, Kazuhiko Hayashi, Isao Nakano, Yoshiki Hirooka, Hidemi Goto

    Hepatology Research   Vol. 46 ( 6 ) page: 601-606   2015.10

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  95. Endoscopic treatment of esophageal varices in hemophiliac patients with liver cirrhosis. Reviewed

    Ishizu Y, Ishigami M, Suzuki N, Kuzuya T, Honda T, Hayashi K, Katano Y, Hirooka Y, Ishikawa T, Matsushita T, Goto H.

    Gastrointest Endosc.   Vol. 81 ( 4 ) page: 1059-60   2015.4

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  96. Clinical impact of HFE mutations in Japanese patients with chronic hepatitis C Reviewed

    Ishizu Y, Katano Y, Honda T, Hayashi K, Ishigami M, Itoh A, Hirooka Y, Nakano I, Goto H.

    J Gastroenterol Hepatol.   Vol. 27 ( 6 ) page: 1112-6   2012.6

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Presentations 3

  1. 食道胃静脈瘤治療症例における肺高血圧症の頻度 ~心電図を用いたスクリーニングによる検討~

    石津洋二、石上雅敏、杉山由晃、吉岡直輝、水野和幸、武藤久哲、横山晋也、田中卓、山本健太、伊藤隆徳、 葛谷貞二、本多隆、藤城光弘

    第28回 日本消化器関連学会週間  2020.11.5 

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    Event date: 2020.11

    Language:Japanese   Presentation type:Oral presentation (general)  

  2. 門脈圧亢進症症例における右心負荷所見の検討

    石津洋二、石上雅敏、杉山由晃、吉岡直輝、水野和幸、武藤久哲、横山晋也、田中卓、山本健太、伊藤隆徳、 葛谷貞二、本多隆、藤城光弘

    第27回日本門脈圧亢進症学会総会  2020.9.10 

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    Event date: 2020.9

    Language:Japanese   Presentation type:Oral presentation (general)  

  3. 肝硬変患者におけるmyosteatosisに寄与する因子の検討

    石津洋二、石上雅敏、杉山由晃、吉岡直輝、水野和幸、武藤久哲、横山晋也、田中卓、山本健太、伊藤隆徳、葛谷貞二、本多隆、藤城光弘

    第56回日本肝臓学会総会  2020.8.28 

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    Event date: 2020.8 - 2020.2

    Language:Japanese   Presentation type:Poster presentation  

KAKENHI (Grants-in-Aid for Scientific Research) 1

  1. サルコペニア患者に対する腸内細菌叢への介入による効果的な運動療法の開発

    Grant number:21K11261  2021.4 - 2024.3

    科学研究費助成事業  基盤研究(C)

    石津 洋二, 本多 隆, 梅垣 宏行, 山本 健太

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    Authorship:Principal investigator 

    Grant amount:\4160000 ( Direct Cost: \3200000 、 Indirect Cost:\960000 )

    サルコペニアに対する治療は運動療法であるが、十分な効果を得られないことが多い。近年、腸内細菌が産生する短鎖脂肪酸が骨格筋と関係している事が明らかになった。短鎖脂肪酸は腸内環境を整えることで炎症を抑え、それにより骨格筋の分解を抑える働きを持つ。さらに筋肉におけるエネルギー代謝にも関連し、運動時の易疲労性に対し予防的に働く。以上のことから、運動療法に短鎖脂肪酸産生を増加させるような腸内細菌叢への介入を加えることで、運動療法の効果を増強できるのではないかと考えた。そこで本研究は、サルコペニアに対し、腸内細菌叢への介入による効果的な運動療法を開発することを目的とする。