Papers - NAKATOCHI Masahiro
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A rapid functional decline type of amyotrophic lateral sclerosis is linked to low expression of TTN Reviewed
Hazuki Watanabe, Naoki Atsuta, Akihiro Hirakawa, Ryoichi Nakamura, Masahiro Nakatochi, Shinsuke Ishigaki, Aritoshi Iida, Shiro Ikegawa, Michiaki Kubo, Daichi Yokoi, Hirohisa Watanabe, Mizuki Ito, Masahisa Katsuno, Yuishin Izumi, Mitsuya Morita, Kazuaki Kanai, Akira Taniguchi, Ikuko Aiba, Koji Abe, Koichi Mizoguchi, Masaya Oda, Osamu Kano, Koichi Okamoto, Satoshi Kuwabara, Kazuko Hasegawa, Takashi Imai, Akihiro Kawata, Masashi Aoki, Shoji Tsuji, Kenji Nakashima, Ryuji Kaji, Gen Sobue
Journal of Neurology, Neurosurgery, and Psychiatry Vol. 87 ( 8 ) page： 851-8 2016.8
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Development and analysis of patient derived xenograft mouse models in intravascular large B-cell lymphoma Reviewed
Kazuyuki Shimada, Satoko Shimada, Keiki Sugimoto, Masahiro Nakatochi, Miyuki Suguro, Akihiro Hirakawa, Toby Dylan Hocking, Ichiro Takeuchi, Takashi Tokunaga, Yusuke Takagi, Akihiko Sakamoto, Tomohiro Aoki, Tomoki Naoe, Shigeo Nakamura, Fumihiko Hayakawa, Masao Seto, Akihiro Tomita, and Hitoshi Kiyoi
Leukemia Vol. 30 ( 7 ) page： 1568-1579 2016.7
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Metallothionein MT2A A-5G polymorphism as a risk factor for chronic kidney disease and diabetes: Cross-sectional and cohort studies Reviewed
Yuta Hattori, Mariko Naito, Masahiko Satoh, Masahiro Nakatochi, Hisao Naito, Masashi Kato, Sahoko Takagi, Takashi Matsunaga, Toshio Seiki, Tae Sasakabe, Shino Suma, Sayo Kawai, Rieko Okada, Asahi Hishida, Nobuyuki Hamajima, Kenji Wakai
Toxicological Sciences Vol. 152 ( 1 ) page： 181-93 2016.7
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Next-generation sequencing of 28 ALS-related genes in a Japanese ALS cohort Reviewed
Ryoichi Nakamura, Jun Sone, Naoki Atsuta, Genki Tohnai, Hazuki Watanabe, Daichi Yokoi, Masahiro Nakatochi, Hirohisa Watanabe, Mizuki Ito, Jo Senda, Masahisa Katsuno, Fumiaki Tanaka, Yuanzhe Li, Yuishin Izumi, Mitsuya Morita, Akira Taniguchi, Osamu Kano, Masaya Oda, Satoshi Kuwabara, Koji Abe, Ikuko Aiba, Koichi Okamoto, Kouichi Mizoguchi, Kazuko Hasegawa, Masashi Aoki, Nobutaka Hattori, Shoji Tsuji, Kenji Nakashima, Ryuji Kaji, Gen Sobue, Japanese Consortium for Amyotrophic Lateral Sclerosis Research (JaCALS)
Neurobiology Aging Vol. 39 page： 219.e1–219.e8 2016.3
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Genome-wide association studies in East Asians identify new loci for waist-hip ratio and waist circumference Reviewed
Wanqing Wen, Norihiro Kato, Joo-Yeon Hwang, Xingyi Guo, Yasuharu Tabara, Huaixing Li, Rajkumar Dorajoo, Xiaobo Yang, Fuu-Jen Tsai, Shengxu Li, Ying Wu, Tangchun Wu, Soriul Kim, Xiuqing Guo, Jun Liang, Dmitry Shungin, Linda S Adair, Koichi Akiyama, Matthew Allison, Qiuyin Cai, Li-Ching Chang, Chien-Hsiun Chen, Yuan-Tsong Chen, Yoon Shin Cho, Bo Youl Choi, Yutang Gao, Min Jin Go, Dongfeng Gu, Bok-Ghee Han, Meian He, James E Hixson, Yanling Hu, Tao Huang, Masato Isono, Keum Ji Jung, Daehee Kang, Young Jin Kim, Yoshikuni Kita, Juyoung Lee, Nanette R. Lee, Jeannette Lee, Yiqin Wang, Jian-Jun Liu, Jirong Long, Sanghoon Moon, Yasuyuki Nakamura, Masahiro Nakatochi, Keizo Ohnaka, Dabeeru Rao, Jiajun Shi, Jae Woong Sull, Aihua Tan, Hirotsugu Ueshima, Chen Wu, Yong-Bing Xiang, Ken Yamamoto, Jie Yao, Xingwang Ye, Mitsuhiro Yokota, Xiaomin Zhang, Yan Zheng, Lu Qi, Jerome I Rotter, Sun Ha Jee, Dongxin Lin, Karen L. Mohlke, Jiang He, Zengnan Mo, Jer-Yuarn Wu, E Shyong Tai, Xu Lin, Tetsuro Miki, Bong-Jo Kim, Fumihiko Takeuchi, Wei Zheng, Xiao-Ou Shu
Scientific Report Vol. 6 page： 17958 2016.1
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Epigenome-wide association study suggests that SNPs in the promoter region of RETN influence plasma resistin level via effects on DNA methylation at neighbouring sites Reviewed
Masahiro Nakatochi, Sahoko Ichihara, Ken Yamamoto, Keizo Ohnaka, Yosuke Kato, Shigeki Yokota, Akihiro Hirashiki, Keiko Naruse, Hiroyuki Asano, Hideo Izawa, Tatsuaki Matsubara, Mitsuhiro Yokota
Diabetologia Vol. 58 page： 2781-2790 2015.12
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miR-342-3p regulates MYC transcriptional activity via direct repression of E2F1 in human lung cancer Reviewed
Mei Chee Tai, Taisuke Kajino, Masahiro Nakatochi, Chinatsu Arima, Yukako Shimada, Motoshi Suzuki, Hiroyuki Miyoshi, Yasushi Yatabe, Kiyoshi Yanagisawa, Takashi Takahashi
Carcinogenesis Vol. 36 ( 12 ) page： 1464-73 2015.12
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Mapping the genetic diversity of HLA haplotypes in the Japanese populations Reviewed
Woei-Yuh Saw, Xuanyao Liu, Chiea-Chuen Khor, Fumihiko Takeuchi, Tomohiro Katsuya, Ryosuke Kimura, Toru Nabika, Takayoshi Ohkubo, Yasuharu Tabara, Ken Yamamoto, Mitsuhiro Yokota, Japanese Genome Variation Consortium, Yik-Ying Teo, Norihiro Kato
Scientific Report Vol. 5 page： 17855 2015.12
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Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation Reviewed
Norihiro Kato, Marie Loh, Fumihiko Takeuchi, Niek Verweij, Xu Wang, Weihua Zhang, Tanika N Kelly, Danish Saleheen, Benjamin Lehne, Irene Mateo Leach, Alexander W Drong, James Abbott, Simone Wahl, Sian-Tsung Tan, William R Scott, Gianluca Campanella, Marc Chadeau-Hyam, Uzma Afzal, Tarunveer S Ahluwalia, Marc Jan Bonder, Peng Chen, Abbas Dehghan, Todd L Edwards, Tõnu Esko, Min Jin Go, Sarah E Harris, Jaana Hartiala, Silva Kasela, Anuradhani Kasturiratne, Chiea-Chuen Khor, Marcus E Kleber, Huaixing Li, Zuan Yu Mok, Masahiro Nakatochi, Nur Sabrina Sapari, Richa Saxena, Alexandre F R Stewart, Lisette Stolk, Yasuharu Tabara, Ai Ling Teh, Ying Wu, Jer-Yuarn Wu, Yi Zhang, Imke Aits, Alexessander Da Silva Couto Alves, Shikta Das, Rajkumar Dorajoo, Jemma C Hopewell, Yun Kyoung Kim, Robert W Koivula, Jian'an Luan, Leo-Pekka Lyytikäinen, Quang N Nguyen, Mark A Pereira, Iris Postmus, Olli T Raitakari, Molly Scannell Bryan, Robert A Scott, Rossella Sorice, Vinicius Tragante, Michela Traglia, Jon White, Ken Yamamoto, Yonghong Zhang, Linda S Adair, Alauddin Ahmed, Koichi Akiyama, Rasheed Asif , Tin Aung, Inês Barroso, Andrew Bjonnes, Timothy R Braun, Hui Cai, Li-Ching Chang, Chien-Hsiun Chen, Ching-Yu Cheng, Yap-Seng Chong, Rory Collins, Regina Courtney, Gail Davies, Graciela Delgado, Loi D Do, Pieter A Doevendans, Ron T Gansevoort, Yu-Tang Gao, Tanja B Grammer, Niels Grarup, Jagvir Grewal, Dongfeng Gu, Gurpreet S Wander, Anna-Liisa Hartikainen, Stanley L Hazen, Jing He, Chew-Kiat Heng, James E Hixson, Albert Hofman, Chris Hsu, Wei Huang, Lise L N Husemoen, Joo-Yeon Hwang, Sahoko Ichihara, Michiya Igase, Masato Isono, Johanne M Justesen, Tomohiro Katsuya, Muhammad G Kibriya, Young Jin Kim, Miyako Kishimoto, Woon-Puay Koh, Katsuhiko Kohara, Meena Kumari, Kenneth Kwek, Nanette R Lee, Jeannette Lee, Jiemin Liao, Wolfgang Lieb, David C M Liewald, Tatsuaki Matsubara, Yumi Matsushita, Thomas Meitinger, Evelin Mihailov, Lili Milani, Rebecca Mills, Nina Mononen, Martina Müller-Nurasyid, Toru Nabika, Eitaro Nakashima, Hong Kiat Ng, Kjell Nikus, Teresa Nutile, Takayoshi Ohkubo, Keizo Ohnaka, Sarah Parish, Lavinia Paternoster, Hao Peng, Annette Peters, Son T Pham, Mohitha J Pinidiyapathirage, Mahfuzar Rahman, Hiromi Rakugi, Olov Rolandsson, Michelle Ann Rozario, Daniela Ruggiero, Cinzia F Sala, Ralhan Sarju, Kazuro Shimokawa, Harold Snieder, Thomas Sparsø, Wilko Spiering, John M Starr, David J Stott, Daniel O Stram, Takao Sugiyama, Silke Szymczak, W H Wilson Tang, Lin Tong, Stella Trompet, Väinö Turjanmaa, Hirotsugu Ueshima, André G Uitterlinden, Satoshi Umemura, Marja Vaarasmaki, Rob M van Dam, Wiek H van Gilst, Dirk J van Veldhuisen, Jorma S Viikari, Melanie Waldenberger, Yiqin Wang, Aili Wang, Rory Wilson, Tien-Yin Wong, Yong-Bing Xiang, Shuhei Yamaguchi, Xingwang Ye, Robin D Young, Terri L Young, Jian-Min Yuan, Xueya Zhou, Folkert W Asselbergs, Marina Ciullo, Robert Clarke, Panos Deloukas, Andre Franke, Paul W Franks, Steve Franks, Yechiel Friedlander, Myron D Gross, Zhirong Guo, Torben Hansen, Marjo-Riitta Jarvelin, Torben Jørgensen, J Wouter Jukema, Mika Kähönen, Hiroshi Kajio, Mika Kivimaki, Jong-Young Lee, Terho Lehtimäki, Allan Linneberg, Tetsuro Miki, Oluf Pedersen, Nilesh J Samani, Thorkild I A Sørensen, Ryoichi Takayanagi, Daniela Toniolo, BIOS -consortium, CARDIo GRAMplusCD , LifeLines Cohort Study, The InterAct Consortium, Habibul Ahsan, Hooman Allayee, Yuan-Tsong Chen, John Danesh, Ian J Deary, Oscar H Franco, Lude Franke, Bastiaan T Heijman, Joanna D Holbrook, Aaron Isaacs, Bong-Jo Kim, Xu Lin, Jianjun Liu, Winfried März, Andres Metspalu, Karen L Mohlke, Dharambir K Sanghera, Xiao-Ou Shu, Joyce B J van Meurs, Eranga Vithana, Ananda R Wickremasinghe, Cisca Wijmenga, Bruce H W Wolffenbuttel, Mitsuhiro Yokota, Wei Zheng, Dingliang Zhu, Paolo Vineis, Soterios A Kyrtopoulos, Jos C S Kleinjans, Mark I McCarthy, Richie Soong, Christian Gieger, James Scott, Yik-Ying Teo, Jiang He, Paul Elliott, E Shyong Tai, Pim van der Harst, Jaspal S Kooner, John C Chambers
Nature Genetics Vol. 47 ( 11 ) page： 1282 2015.11
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Increased Acid Ceramidase Expression depends on Upregulation of Androgen-dependent Deubiquitinases, USP2, in a Human Prostate Cancer Cell Line, LNCaP Reviewed
Naoki Mizutani, Minami Inoue, Yukari Omori, Hiromi Ito, Keiko Tamiya-Koizumi, Akira Takagi, Tetsuhito Kojima, Mitsuhiro Nakamura, Soichiro Iwaki, Masahiro Nakatochi, Motoshi Suzuki, Yoshinori Nozawa, Takashi Murate
Jounal of Biochemistry Vol. 158 ( 4 ) page： 309-19 2015.10
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Increased SPHK2 transcription of human colon cancer cells in serum-depleted culture: the involvement of CREB transcription factor Reviewed
Naoki Mizutani, Yukari Omori, Koji Tanaka, Hiromi Ito, Akira Takagi, Tetsuhito Kojima, Masahiro Nakatochi, Hideo Ogiso, Yoshiyuki Kawamoto, Mitsuhiro Nakamura, Motoshi Suzuki, Mamoru Kyogashima, Keiko Tamiya-Koizumi, Yoshinori Nozawa, Takashi Murate
Journal of Cellular Biochemistry Vol. 116 ( 10 ) page： 2227-38 2015.3
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Identification of an interaction between VWF rs7965413 and platelet count as a novel risk marker for metabolic syndrome: an extensive search of candidate polymorphisms in a case-control study Reviewed
Masahiro Nakatochi, Yasunori Ushida, Yoshinari Yasuda, Yasuko Yoshida, Shun Kawai, Ryuji Kato, Toru Nakashima, Masamitsu Iwata, Yachiyo Kuwatsuka, Masahiko Ando, Nobuyuki Hamajima, Takaaki Kondo, Hiroaki Oda, Mutsuharu Hayashi, Sawako Kato, Makoto Yamaguchi, Shoichi Maruyama, Seiichi Matsuo, Hiroyuki Honda
PLoS One Vol. 10 ( 2 ) page： e0117591 2015.2
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A meta-analysis of genome-wide association studies for adiponectin level in East Asians identifies a novel locus near WDR11-FGFR2 Reviewed
Ying Wu*, He Gao*, Huaixing Li*, Yasuharu Tabara*, Masahiro Nakatochi*(co-1st author), Yen-Feng Chiu*, Eun Jung Park*, Wanqing Wen*, Linda S. Adair, Judith B. Borja, Qiuyin Cai, Yi-Cheng Chang, Peng Chen, Damien C. Croteau-Chonka, Marie P. Fogarty, Wei Gan, Chih-Tsueng He, Chao A. Hsiung, Chii-Min Hwu, Sahoko Ichihara, Michiya Igase, Jaeseong Jo, Norihiro Kato, Ryuichi Kawamoto, Christophor W. Kuzawa, Jeannette JM. Lee, Jianjun Liu, Ling Lu, Thomas W. McDade, Haruhiko Osawa, Wayne H-H Sheu, Yvonne Teo, Swarooparani Vadlamudi, Rob M. van Dam, Yiqin Wang, Yong-Bing Xiang, Ken Yamamoto, Xingwang Ye, Terri L. Young, Wei Zheng, Jingwen Zhu, Xiao-Ou Shu, Chol Shin, Sun Ha Jee, Lee-Ming Chuang, Tetsuro Miki, Mitsuhiro Yokota, Xu Lin, Karen L Mohlke, E Shyong Tai
Human Molecular Genetics Vol. 23 ( 4 ) page： 1108 2014
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Lung adenocarcinoma subtypes definable by lung development-related miRNA expression profiles in association with clinicopathologic features Reviewed
Arima C, Kajino T, Tamada Y, Imoto S, Shimada Y, Nakatochi M, Suzuki M, Isomura H, Yatabe Y, Yamaguchi T, Yanagisawa K, Miyano S, Takahashi T
Carcinogenesis Vol. 35 ( 10 ) page： 2224-2231 2014
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全網羅ミルクペプチドアレイを用いたアレルギー診断ペプチド探索への分布関数解析法の応用 Reviewed
中杤昌弘, 片山真, 加藤竜司, 大河内美奈, 高瀬智和, 吉田安子, 川瀬三雄, 本多裕之
化学工学論文集 Vol. 39 ( 1 ) page： 40-45 2013
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Identification of a glutamic acid repeat polymorphism of ALMS1 as a novel genetic risk marker for early-onset myocardial infarction by genome-wide linkage analysis Reviewed
Sahoko Ichihara, Ken Yamamoto, Hiroyuki Asano, Masahiro Nakatochi, Mayo Sukegawa, Gaku Ichihara, Hideo Izawa, Akihiro Hirashiki, Fumimaro Takatsu, Hisashi Umeda, Mitsunori Iwase, Haruo Inagaki, Haruo Hirayama, Takahito Sone, Kazuhiko Nishigaki, Shinya Minatoguchi, Myeong-Chan Cho, Yangsoo Jang, Hyo-Soo Kim, Jeong E. Park, Saeko Tada-Oikawa, Hidetoshi Kitajima, Tatsuaki Matsubara, Kenji Sunagawa, Hiroaki Shimokawa, Akinori Kimura, Jong-Young Lee, Toyoaki Murohara, Ituro Inoue, Mitsuhiro Yokota
Circulation Cardiovascular Genetics Vol. 6 ( 6 ) page： 569-578 2013
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A genome-wide association study of a coronary artery disease risk variant Reviewed
Ji-Young Lee, Bok-Soo Lee, Dong-Jik Shin, Kyung Woo Park, Young-Ah Shin, Kwang Joong Kim, Lyong Heo, Ji Young Lee, Yun Kyoung Kim, Young Jin Kim, Chang Bum Hong, Sang-Hak Lee, Dankyu Yoon, Hyo Jung Ku, Il-Young Oh, Bong-Jo Kim, Juyoung Lee, Seon-Joo Park, Jimin Kim, Hye-kyung Kawk, Jong-Eun Lee, Hye-kyung Park, Jae-Eun Lee, Hye-young Nam, Hyun-young Park, Chol Shin, Mitsuhiro Yokota, Hiroyuki Asano, Masahiro Nakatochi, Tatsuaki Matsubara, Hidetoshi Kitajima, Ken Yamamoto, Hyung-Lae Kim, Bok-Ghee Han, Myeong Chan Cho, Yangsoo Jang, Hyo-Soo Kim, Jeong Euy Park and Jong-Young Lee
Journal of Human Genetics Vol. 58 ( 3 ) page： 120-126 2013
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Genome-wide association study of coronary artery disease in the Japanese Reviewed
Fumihiko Takeuchi, Mitsuhiro Yokota, Ken Yamamoto, Eitaro Nakashima, Tomohiro Katsuya, Hiroyuki Asano, Masato Isono, Toru Nabika, Takao Sugiyama, Akihiro Fujioka, Nobuhisa Awata, Keizo Ohnaka, Masahiro Nakatochi, Hidetoshi Kitajima, Hiromi Rakugi, Jiro Nakamura, Takayoshi Ohkubo, Yutaka Imai, Kazuaki Shimamoto, Yukio Yamori, Shuhei Yamaguchi, Shotai Kobayashi, Ryoichi Takayanagi, Toshio Ogihara and Norihiro Kato
European Journal of Human Genetics Vol. 20 ( 3 ) page： 333-340 2012
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The ratio of adiponectin to homeostasis model assessment of insulin resistance is a powerful index of each component of metabolic syndrome in an aged Japanese population: Results from the KING Study Reviewed
Masahiro Nakatochi, Seiko Miyata, Daisuke Tanimura, Hideo Izawa, Hiroyuki Asano, Yosuke Murase, Ryuji Kato, Sahoko Ichihara, Keiko Naruse, Tatsuaki Matsubara, Hiroyuki Honda, Mitsuhiro Yokota
Diabetes Research and Clinical Practice Vol. 92 ( 3 ) page： e61-65 2011
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Relation of a common variant of the adiponectin gene to serum adiponectin concentration and metabolic traits in an aged Japanese population Reviewed
Daisuke Tanimura, Rei Shibata, Hideo Izawa, Akihiro Hirashiki, Hiroyuki Asano, Yosuke Murase, Seiko Miyata, Masahiro Nakatochi, Noriyuki Ouchi, Sahoko Ichihara, Kenji Yasui, Tsutomu Yoshida, Keiko Naruse, Tatsuaki Matsubara and Mitsuhiro Yokota
European Journal of Human Genetics Vol. 19 ( 3 ) page： 262-269 2011