Faculty Profiles - SAKAMOTO Koji

Papers - SAKAMOTO Koji

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Pulmonary rehabilitation in patients with idiopathic pulmonary fibrosis: Comparison with chronic obstructive pulmonary disease

Arizono S., Taniguchi H., Sakamoto K., Kondoh Y., Kimura T., Kataoka K., Ogawa T., Watanabe F., Tabira K., Kozu R.

Sarcoidosis Vasculitis and Diffuse Lung Diseases Vol. 34 ( 4 ) page： 283 - 289 2017

Language：Japanese Publishing type：Research paper (scientific journal) Publisher：Sarcoidosis Vasculitis and Diffuse Lung Diseases

Background: While the efficacy of pulmonary rehabilitation (PR) in chronic obstructive pulmonary disease (COPD) has been well established, emerging evidence also suggests its benefit in idiopathic pulmonary fibrosis (IPF). However, the differences and similarities between how PR affects diseases with different physiologies remain unknown. Objective: This study aimed to compare the efficacy of PR in COPD and IPF patients by performing multifactorial evaluation with various exercise capacity measurements, and dyspnea and health-related quality of life (QoL) assessment. Methods: Twenty-two IPF patients (%vital capacity: 72%) and 27 COPD patients (%forced expiratory volume1: 43%) were recruited. Subjects who completed a 10-week outpatient PR program were analyzed. We assessed five exercise capacity indicators (6-minute walking distance, incremental shuttle walking distance, endurance time, peak work rate, and peak values for oxygen uptake [peak VO2]), dyspnea (Baseline Dyspnea Index: BDI), and health-related QoL (St. George's Respiratory Questionnaire: SGRQ) at baseline and immediately following completion of the PR program. Results: After 10 weeks of PR, all exercise capacity measurements, except VO2, as well as BDI and SGRQ score improved significantly (p<0.05) in both disease groups. The magnitude of the observed changes in each outcome, assessed by the effect size, was comparable between IPF and COPD patients. This was also true for endurance time, the measurement most responsive to PR, with a large effect size. Conclusions: PR can result in comparable improvements in exercise capacity, including endurance time, and dyspnea and HRQoL in both IPF and COPD patients after 10 weeks of exercise training.

Scopus

Impact of Thin-Section Computed Tomography-Determined Combined Pulmonary Fibrosis and Emphysema on Outcomes Among Patients With Resected Lung Cancer. Reviewed

Hashimoto N, Iwano S, Kawaguchi K, Fukui T, Fukumoto K, Nakamura S, Mori S, Sakamoto K, Wakai K, Yokoi K, Hasegawa Y

The Annals of thoracic surgery Vol. 102 ( 2 ) page： 440-7 2016.8

Mean pulmonary arterial pressure as a prognostic indicator in connective tissue disease associated with interstitial lung disease: a retrospective cohort study. Reviewed

Takahashi K, Taniguchi H, Ando M, Sakamoto K, Kondoh Y, Watanabe N, Kimura T, Kataoka K, Suzuki A, Ito S, Hasegawa Y

BMC pulmonary medicine Vol. 16 ( 1 ) page： 55 2016.4

Biomarkers in the Evaluation and Management of Idiopathic Pulmonary Fibrosis. Reviewed

Tzouvelekis A, Herazo-Maya J, Sakamoto K, Bouros D

Current topics in medicinal chemistry Vol. 16 ( 14 ) page： 1587-98 2016

Hypoxia-induced modulation of PTEN activity and EMT phenotypes in lung cancers. Reviewed

Kohnoh T, Hashimoto N, Ando A, Sakamoto K, Miyazaki S, Aoyama D, Kusunose M, Kimura M, Omote N, Imaizumi K, Kawabe T, Hasegawa Y

Cancer cell international Vol. 16 page： 33 2016

Lung-Dominant Connective Tissue Disease: Clinical, Radiologic, and Histologic Features. Reviewed

Omote N, Taniguchi H, Kondoh Y, Watanabe N, Sakamoto K, Kimura T, Kataoka K, Johkoh T, Fujimoto K, Fukuoka J, Otani K, Nishiyama O, Hasegawa Y

Chest Vol. 148 ( 6 ) page： 1438-1446 2015.12

Direct regulation of transforming growth factor β-induced epithelial-mesenchymal transition by the protein phosphatase activity of unphosphorylated PTEN in lung cancer cells. Reviewed

Vol. 106 ( 12 ) page： 1693-704 2015.12

Recombinant Human Thrombomodulin in Acute Exacerbation of Idiopathic Pulmonary Fibrosis. Reviewed

Kataoka K, Taniguchi H, Kondoh Y, Nishiyama O, Kimura T, Matsuda T, Yokoyama T, Sakamoto K, Ando M

Chest Vol. 148 ( 2 ) page： 436-443 2015.8

Risk stratification by the lower limit of normal of FEV1/FVC for postoperative outcomes in patients with COPD undergoing thoracic surgery. Reviewed

Osuka S, Hashimoto N, Sakamoto K, Wakai K, Yokoi K, Hasegawa Y

Respiratory investigation Vol. 53 ( 3 ) page： 117-23 2015.5

Broader criteria of undifferentiated connective tissue disease in idiopathic interstitial pneumonias. Reviewed

Kondoh Y, Johkoh T, Fukuoka J, Arakawa H, Tanaka T, Watanabe N, Sakamoto K, Kataoka K, Kimura T, Taniguchi H

Respiratory medicine Vol. 109 ( 3 ) page： 389-96 2015.3

Endurance time is the most responsive exercise measurement in idiopathic pulmonary fibrosis. Reviewed

Arizono S, Taniguchi H, Sakamoto K, Kondoh Y, Kimura T, Kataoka K, Ogawa T, Watanabe F, Nishiyama O, Nishimura K, Kozu R, Tabira K

Respiratory care Vol. 59 ( 7 ) page： 1108-15 2014.7

Let-7d microRNA affects mesenchymal phenotypic properties of lung fibroblasts. Reviewed

Huleihel L, Ben-Yehudah A, Milosevic J, Yu G, Pandit K, Sakamoto K, Yousef H, LeJeune M, Coon TA, Redinger CJ, Chensny L, Manor E, Schatten G, Kaminski N

American journal of physiology. Lung cellular and molecular physiology Vol. 306 ( 6 ) page： L534-42 2014.3

Crizotinib-induced acute interstitial lung disease in a patient with EML4-ALK positive non-small cell lung cancer and chronic interstitial pneumonia. Reviewed

Watanabe N, Nakahara Y, Taniguchi H, Kimura T, Kondoh Y, Kataoka K, Sakamoto K

Acta oncologica (Stockholm, Sweden) Vol. 53 ( 1 ) page： 158-60 2014.1

Efficacy of combined therapy with cyclosporin and low-dose prednisolone in interstitial pneumonia associated with connective tissue disease. Reviewed

Watanabe N, Sakamoto K, Taniguchi H, Kondoh Y, Kimura T, Kataoka K, Ono K, Fukuoka J, Nishiyama O, Hasegawa Y

Respiration; international review of thoracic diseases Vol. 87 ( 6 ) page： 469-77 2014

Significance of pulmonary arterial pressure as a prognostic indicator in lung-dominant connective tissue disease. Reviewed

Suzuki A, Taniguchi H, Watanabe N, Kondoh Y, Kimura T, Kataoka K, Matsuda T, Yokoyama T, Sakamoto K, Nishiyama O, Hasegawa Y

PloS one Vol. 9 ( 9 ) page： e108339 2014

Endobronchial ultrasound transbronchial needle aspiration in older people. Reviewed

Okachi S, Imai N, Imaizumi K, Hase T, Shindo Y, Sakamoto K, Aso H, Wakahara K, Hashimoto I, Ito S, Hashimoto N, Sato M, Kondo M, Hasegawa Y

Geriatrics & gerontology international Vol. 13 ( 4 ) page： 986-92 2013.10

Quadriceps weakness contributes to exercise capacity in nonspecific interstitial pneumonia. Reviewed

Watanabe F, Taniguchi H, Sakamoto K, Kondoh Y, Kimura T, Kataoka K, Ogawa T, Arizono S, Nishiyama O, Hasegawa Y

Respiratory medicine Vol. 107 ( 4 ) page： 622-8 2013.4

Pulmonary hypertension as a prognostic indicator at the initial evaluation in idiopathic pulmonary fibrosis. Reviewed

Kimura M, Taniguchi H, Kondoh Y, Kimura T, Kataoka K, Nishiyama O, Aso H, Sakamoto K, Hasegawa Y

Respiration; international review of thoracic diseases Vol. 85 ( 6 ) page： 456-63 2013

Involvement of TGFβ-induced phosphorylation of the PTEN C-terminus on TGFβ-induced acquisition of malignant phenotypes in lung cancer cells. Reviewed

Vol. 8 ( 11 ) page： e81133 2013

Predictors of the need to initiate noninvasive ventilation in stable outpatients with acute exacerbation of chronic obstructive pulmonary disease. Reviewed

Taga S, Taniguchi H, Watanabe N, Kondoh Y, Kimura T, Kataoka K, Aso H, Sakamoto K, Hasegawa Y

Internal medicine (Tokyo, Japan) Vol. 52 ( 16 ) page： 1781-6 2013

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Papers - SAKAMOTO Koji