Updated on 2022/05/13

写真a

 
TANAKA Chie
 
Organization
Nagoya University Hospital Gastroenterological Surgery 2 Associate professor of hospital
Graduate School
Graduate School of Medicine
Title
Associate professor of hospital

Degree 1

  1. 博士(医学) ( 2010.3   名古屋大学 ) 

Research Areas 1

  1. Life Science / Digestive surgery

Research History 2

  1. 名古屋大学医学部附属病院消化器外科二講師

    2021.4

  2. 名古屋大学医学部附属病院消化器外科二病院講師

    2018.4 - 2021.3

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    Country:Japan

Education 1

  1. Nagoya University   Graduate School, Division of Medical Sciences

    - 2010.3

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    Country: Japan

Professional Memberships 10

  1. 日本外科学会

  2. 日本消化器外科学会

  3. 日本胃癌学会

  4. 日本内視鏡外科学会

  5. 日本ロボット外科学会

  6. 日本肥満症治療学会

  7. 日本大腸肛門病学会

  8. 日本癌学会

  9. 日本癌治療学会

  10. 日本臨床外科学会

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Committee Memberships 4

  1. 日本消化器外科学会   学術委員会委員  

    2021.9   

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    Committee type:Academic society

  2. 日本消化器外科学会   男女共同参画ワーキンググループ委員  

    2021.9   

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    Committee type:Academic society

  3. 日本消化器外科学会   試験問題作成委員会委員(胃十二指腸)  

    2021.9   

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    Committee type:Academic society

  4. 日本消化器外科学会   データベース委員会委員  

    2021.9   

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    Committee type:Academic society

Awards 3

  1. 日本内視鏡外科学会 ePoster Award

    2017.12   日本内視鏡外科学会  

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    Award type:Award from Japanese society, conference, symposium, etc.  Country:Japan

  2. 日本癌治療学会 優秀演題賞

    2008   日本癌治療学会  

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    Award type:Award from Japanese society, conference, symposium, etc.  Country:Japan

  3. 優秀演題賞

    日本ロボット外科学会   胃癌におけるアプローチ別の胃切除術後の治療成績についての検討

 

Papers 171

  1. Detection of indocyanine green fluorescence to determine tumor location during laparoscopic gastrectomy for gastric cancer: Results of a prospective study

    Tanaka C, Kanda M, Funasaka K, Miyahara R, Murotani K, Tanaka Y, Takeda S, Kobayashi D, Hirooka Y, Fujiwara M, Goto H, Kodera Y.

    Asian Journal of Endoscopic Surgery   Vol. 13 ( 2 ) page: 160-167   2020.4

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    Authorship:Lead author, Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/ases.12710. 

  2. Expression of cellular retinoic acid binding protein 1 predicts peritoneal recurrence of gastric cancer.

    Sakata K, Kanda M, Shimizu D, Nakamura S, Inokawa Y, Hattori N, Hayashi M, Tanaka C, Nakayama G, Kodera Y

    International journal of oncology   Vol. 60 ( 6 )   2022.6

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    Language:English  

    DOI: 10.3892/ijo.2022.5353

    PubMed

  3. Lysosomal-associated membrane protein family member 5 promotes the metastatic potential of gastric cancer cells

    Umeda Shinichi, Kanda Mitsuro, Shimizu Dai, Nakamura Shunsuke, Sawaki Koichi, Inokawa Yoshikuni, Hattori Norifumi, Hayashi Masamichi, Tanaka Chie, Nakayama Goro, Kodera Yasuhiro

    GASTRIC CANCER   Vol. 25 ( 3 ) page: 558 - 572   2022.5

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  4. Direct Observation of Retinal Microvessels in Cancer Patients After Systemic Administration of Bevacizumab and Oxaliplatin.

    Mitsuma A, Ito Y, Shimokata T, Tanaka C, Uehara K, Nakayama G, Terasaki H, Ando Y

    Cancer diagnosis & prognosis   Vol. 2 ( 3 ) page: 330 - 335   2022.5

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    Language:English  

    DOI: 10.21873/cdp.10113

    PubMed

  5. ASO Visual Abstract: Prognostic Value of a Modified Albumin-Bilirubin Grade Designed for Patients with Esophageal Squamous Cell Carcinoma after Radical Resection.

    Shinozuka T, Kanda M, Shimizu D, Tanaka C, Inokawa Y, Hattori N, Hayashi M, Koike M, Kodera Y

    Annals of surgical oncology     2022.4

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    Language:English  

    DOI: 10.1245/s10434-022-11784-x

    PubMed

  6. Prognostic Value of a Modified Albumin-Bilirubin Score Designed for Patients with Esophageal Squamous Cell Carcinoma After Radical Resection

    Shinozuka Takahiro, Kanda Mitsuro, Shimizu Dai, Tanaka Chie, Inokawa Yoshikuni, Hattori Norifumi, Hayashi Masamichi, Koike Masahiko, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY     2022.4

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  7. Prognostic impact of a microscopic positive margin in patients undergoing gastrectomy for gastric cancer: a propensity score-matched analysis of a multi-institutional dataset

    Nakanishi Koki, Kanda Mitsuro, Ito Seiji, Mochizuki Yoshinari, Teramoto Hitoshi, Ishigure Kiyoshi, Murai Toshifumi, Asada Takahiro, Ishiyama Akiharu, Matsushita Hidenobu, Shimizu Dai, Tanaka Chie, Fujiwara Michitaka, Murotani Kenta, Kodera Yasuhiro

    SURGERY TODAY   Vol. 52 ( 4 ) page: 559 - 566   2022.4

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  8. Increased Risk of Thyroid Dysfunction by PD-1 and CTLA-4 Blockade in Patients Without Thyroid Autoantibodies at Baseline

    Iwama Shintaro, Kobayashi Tomoko, Yasuda Yoshinori, Okuji Takayuki, Ito Masaaki, Ando Masahiko, Zhou Xin, Yamagami Ayana, Onoue Takeshi, Kawaguchi Yohei, Miyata Takashi, Sugiyama Mariko, Takagi Hiroshi, Hagiwara Daisuke, Suga Hidetaka, Banno Ryoichi, Hase Tetsunari, Morise Masahiro, Wakahara Keiko, Yokota Kenji, Kato Masashi, Nishio Naoki, Tanaka Chie, Miyata Kazushi, Ogura Atsushi, Ito Takanori, Sawada Tsunaki, Shimokata Tomoya, Niimi Kaoru, Ohka Fumiharu, Ishigami Masatoshi, Gotoh Momokazu, Hashimoto Naozumi, Saito Ryuta, Kiyoi Hitoshi, Kajiyama Hiroaki, Ando Yuichi, Hibi Hideharu, Sone Michihiko, Akiyama Masashi, Kodera Yasuhiro, Arima Hiroshi

    JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM   Vol. 107 ( 4 ) page: E1620 - E1630   2022.3

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  9. Drain Amylase Concentrations at 3 h After Gastrectomy Enhance Early Prediction of Postoperative Peripancreatic Inflammatory Fluid Collection

    Nakanishi Koki, Kanda Mitsuro, Tanaka Chie, Takeda Shigeomi, Tanaka Katsuhito, Shimizu Dai, Inokawa Yoshikuni, Hattori Norifumi, Hayashi Masamichi, Nakayama Goro, Fujiwara Michitaka, Kodera Yasuhiro

    WORLD JOURNAL OF SURGERY   Vol. 46 ( 3 ) page: 648 - 655   2022.3

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  10. Effects of creating a jejunal pouch on postoperative quality of life after total gastrectomy: A cross-sectional study

    Tsuji Toshikatsu, Isobe Taro, Seto Yasuyuki, Tanaka Chie, Kojima Kazuyuki, Motoori Masaaki, Ikeda Masami, Nitta Toshikatsu, Oshio Atsushi, Nakada Koji

    ANNALS OF GASTROENTEROLOGICAL SURGERY   Vol. 6 ( 1 ) page: 63 - 74   2022.1

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  11. Impact of molecular surgical margin analysis on the prediction of pancreatic cancer recurrences after pancreaticoduodenectomy

    Sunagawa Yuki, Hayashi Masamichi, Yamada Suguru, Tanabe Hiroshi, Kurimoto Keisuke, Tanaka Nobutake, Sonohara Fuminori, Inokawa Yoshikuni, Takami Hideki, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    CLINICAL EPIGENETICS   Vol. 13 ( 1 ) page: 172   2021.12

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  12. Neoadjuvant docetaxel, oxaliplatin plus S-1 for treating clinical stage III squamous cell carcinoma of the esophagus: Study protocol of an open-label phase II trial

    Kanda Mitsuro, Shimizu Dai, Miyata Kazushi, Maeda Osamu, Tanaka Chie, Inokawa Yoshikuni, Hattori Norofumi, Hayashi Masamichi, Ando Masahiko, Kuwatsuka Yachiyo, Murotani Kenta, Nakayama Goro, Koike Masahiko, Ando Yuichi, Ebata Tomoki, Kodera Yasuhiro

    CONTEMPORARY CLINICAL TRIALS COMMUNICATIONS   Vol. 24   page: 100853   2021.12

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  13. E-PASS scoring system serves as a predictor of short- and long-term outcomes in gastric cancer surgery

    Nakanishi Koki, Kanda Mitsuro, Ito Seiji, Mochizuki Yoshinari, Teramoto Hitoshi, Ishigure Kiyoshi, Murai Toshifumi, Asada Takahiro, Ishiyama Akiharu, Matsushita Hidenobu, Kobayashi Daisuke, Shimizu Dai, Tanaka Chie, Fujiwara Michitaka, Murotani Kenta, Kodera Yasuhiro

    SURGERY TODAY     2021.10

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  14. Blockade of CHRNB2 signaling with a therapeutic monoclonal antibody attenuates the aggressiveness of gastric cancer cells

    Kanda Mitsuro, Shimizu Dai, Nakamura Shunsuke, Sawaki Koichi, Umeda Shinichi, Miwa Takashi, Tanaka Haruyoshi, Inokawa Yoshikuni, Hattori Norifumi, Hayashi Masamichi, Tanaka Chie, Nakayama Goro, Iguchi Yohei, Katsuno Masahisa, Kodera Yasuhiro

    ONCOGENE   Vol. 40 ( 36 ) page: 5495 - 5504   2021.9

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  15. Efficacy of Splenectomy for Proximal Gastric Cancer with Greater Curvature Invasion or Type 4 Tumor: a Propensity Score Analysis of a Multi-Institutional Dataset

    Ito Seiji, Kanda Mitsuro, Mochizuki Yoshinari, Teramoto Hitoshi, Ishigure Kiyoshi, Murai Toshifumi, Asada Takahiro, Ishiyama Akiharu, Matsushita Hidenobu, Tanaka Chie, Kobayashi Daisuke, Fujiwara Michitaka, Murotani Kenta, Kodera Yasuhiro

    WORLD JOURNAL OF SURGERY   Vol. 45 ( 9 ) page: 2840 - 2848   2021.9

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  16. Surgical outcomes in gastroenterological surgery in Japan: Report of the National Clinical Database 2011-2019.

    Marubashi S, Takahashi A, Kakeji Y, Hasegawa H, Ueno H, Eguchi S, Endo I, Goi T, Saiura A, Sasaki A, Takiguchi S, Takeuchi H, Tanaka C, Hashimoto M, Hiki N, Horiguchi A, Masaki T, Yoshida K, Gotoh M, Konno H, Yamamoto H, Miyata H, Seto Y, Kitagawa Y, National Clinical Database.

    Annals of gastroenterological surgery   Vol. 5 ( 5 ) page: 639 - 658   2021.9

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    Language:English  

    DOI: 10.1002/ags3.12462

    PubMed

  17. A Possible Definition of Oligometastasis in Pancreatic Cancer and Associated Survival Outcomes

    Yamanaka Masaya, Hayashi Masamichi, Yamada Suguru, Sonohara Fuminori, Takami Hideki, Inokawa Yoshikuni, Shimizu Dai, Hattori Norifumi, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    ANTICANCER RESEARCH   Vol. 41 ( 8 ) page: 3933 - 3940   2021.8

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  18. Accurate Prediction of Prognosis After Radical Resection of Gastric Cancer by the Modified Systemic Inflammation Score; a Multicenter Dataset Analysis

    Inagaki Kota, Kanda Mitsuro, Nakanishi Koki, Ito Seiji, Mochizuki Yoshinari, Teramoto Hitoshi, Ishigure Kiyoshi, Murai Toshifumi, Asada Takahiro, Ishiyama Akiharu, Matsushita Hidenobu, Tanaka Chie, Kobayashi Daisuke, Fujiwara Michitaka, Murotani Kenta, Kodera Yasuhiro

    WORLD JOURNAL OF SURGERY   Vol. 45 ( 8 ) page: 2513 - 2520   2021.8

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  19. G-protein subunit gamma-4 expression has potential for detection, prediction and therapeutic targeting in liver metastasis of gastric cancer

    Tanaka Haruyoshi, Kanda Mitsuro, Miwa Takashi, Umeda Shinichi, Sawaki Koichi, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    BRITISH JOURNAL OF CANCER   Vol. 125 ( 2 ) page: 220 - 228   2021.7

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  20. High Serum Uric Acid Levels Could Be a Risk Factor of Hepatocellular Carcinoma Recurrences

    Hayashi Masamichi, Yamada Suguru, Tanabe Hiroshi, Takami Hideki, Inokawa Yoshikuni, Sonohara Fuminori, Shimizu Dai, Hattori Norifumi, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL   Vol. 73 ( 6 ) page: 996 - 1003   2021.7

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  21. Novel prognostic implications of YTH domain family 2 in resected hepatocellular carcinoma

    Nakagawa Nobuhiko, Sonohara Fuminori, Tanaka Katsuhito, Sunagawa Yuki, Inokawa Yoshikuni, Takami Hideki, Hayashi Masamichi, Yamada Suguru, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    ONCOLOGY LETTERS   Vol. 22 ( 1 ) page: 538   2021.7

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  22. miR-23b-3p Plays an Oncogenic Role in Hepatocellular Carcinoma

    Hayashi Masamichi, Yamada Suguru, Kurimoto Keisuke, Tanabe Hiroshi, Hirabayashi Sho, Sonohara Fuminori, Inokawa Yoshikuni, Takami Hideki, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   Vol. 28 ( 6 ) page: 3416 - 3426   2021.6

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  23. Short-term outcomes of gastrectomy after neoadjuvant chemotherapy for clinical stage III gastric cancer: propensity score-matched analysis of a multi-institutional database

    Umeda Shinichi, Kanda Mitsuro, Nakanishi Koki, Ito Seiji, Mochizuki Yoshinari, Teramoto Hitoshi, Ishigure Kiyoshi, Murai Toshifumi, Asada Takahiro, Ishiyama Akiharu, Matsushita Hidenobu, Shimizu Dai, Kobayashi Daisuke, Tanaka Chie, Fujiwara Michitaka, Murotani Kenta, Kodera Yasuhiro

    SURGERY TODAY   Vol. 51 ( 5 ) page: 821 - 828   2021.5

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  24. Hepatic metastasis of gastric cancer is associated with enhanced expression of ethanolamine kinase 2 via the p53-Bcl-2 intrinsic apoptosis pathway

    Miwa Takashi, Kanda Mitsuro, Shimizu Dai, Umeda Shinichi, Sawaki Koichi, Tanaka Haruyoshi, Tanaka Chie, Hattori Norifumi, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    BRITISH JOURNAL OF CANCER   Vol. 124 ( 8 ) page: 1449 - 1460   2021.4

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  25. Peritoneal Lavage Tumor DNA as a Novel Biomarker for Predicting Peritoneal Recurrence in Pancreatic Ductal Adenocarcinoma Reviewed

    Suenaga Masaya, Fujii Tsutomu, Yamada Suguru, Hayashi Masamichi, Shinjo Keiko, Takami Hideki, Niwa Yukiko, Sonohara Fuminori, Shimizu Dai, Kanda Mitsuro, Kobayashi Daisuke, Tanaka Chie, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kondo Yutaka, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   Vol. 28 ( 4 ) page: 2277 - 2286   2021.4

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  26. Genome-wide identification and characterization of circular RNA in resected hepatocellular carcinoma and background liver tissue Reviewed

    Sunagawa Yuki, Yamada Suguru, Sonohara Fuminori, Kurimoto Keisuke, Tanaka Nobutake, Suzuki Yunosuke, Inokawa Yoshikuni, Takami Hideki, Hayashi Masamichi, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    SCIENTIFIC REPORTS   Vol. 11 ( 1 ) page: 6016   2021.3

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  27. Development of novel combination cancer immunotherapy using anti-PD-1 and anti-PD-L1 antibody

    Hasegawa Hirotaka, Sugiyama Daisuke, Kanda Mitsuro, Hayashi Masamichi, Tanaka Chie, Yamada Suguru, Nakayama Goro, Koike Masahiko, Nomoto Shuji, Fujiwara Michitaka, Kodera Yasuhiro, Nishikawa Hiroyoshi

    CANCER SCIENCE   Vol. 112   page: 741 - 741   2021.2

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    Language:Japanese  

    Web of Science

  28. STRA6 expression serves as a prognostic biomarker of gastric cancer

    Nakamura Shunsuke, Kanda Mitsuro, Shimizu Dai, Sawaki Koichi, Tanaka Chie, Hattori Norifumi, Hayashi Masamichi, Yamada Suguru, Koike Masahiko, Kodera Yasuhiro

    CANCER SCIENCE   Vol. 112   page: 780 - 780   2021.2

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    Language:Japanese  

    Web of Science

  29. Function and prognostic value of melanoma-associated antigen-D4 protein in esophageal squamous cell carcinoma

    Sawaki Koichi, Kanda Mitsuro, Sato Yusuke, Shimizu Dai, Uno Yasuo, Umeda Shinichi, Hattori Norifumi, Hayashi Masamichi, Tanaka Chie, Yamada Suguru, Nakayama Goro, Motoyama Satoru, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER SCIENCE   Vol. 112   page: 531 - 531   2021.2

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    Language:Japanese  

    Web of Science

  30. Randomised phase II trial of capecitabine plus oxaliplatin with continuous versus intermittent use of oxaliplatin as adjuvant chemotherapy for stage II/III colon cancer (CCOG-1302 study)

    Nakayama Goro, Takano Nao, Taniguchi Hiroya, Ishigure Kiyoshi, Yokoyama Hiroyuki, Teramoto Hitoshi, Hashimoto Ryoji, Sakai Mitsuru, Ishiyama Akiharu, Kinoshita Takashi, Hayashi Naomi, Nakamura Masanori, Hattori Norifumi, Sato Yusuke, Umeda Shinichi, Uehara Kei, Aiba Toshisada, Sonohara Fuminori, Hayashi Masamichi, Kanda Mitsuro, Kobayashi Daisuke, Tanaka Chie, Yamada Suguru, Koike Masahiko, Fujiwara Michitaka, Murotani Kenta, Ando Masahiko, Ando Yuichi, Muro Kei, Kodera Yasuhiro

    EUROPEAN JOURNAL OF CANCER   Vol. 144   page: 61 - 71   2021.2

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  31. Tissue RNFT2 Expression Levels Are Associated With Peritoneal Recurrence and Poor Prognosis in Gastric Cancer

    Sasahara Masahiro, Kanda Mitsuro, Shimizu Dai, Tanaka Chie, Inokawa Yoshikuni, Hattori Norifumi, Hayashi Masamichi, Nakayama Goro, Kodera Yasuhiro

    ANTICANCER RESEARCH   Vol. 41 ( 2 ) page: 609 - 617   2021.2

  32. Tissue RNFT2 Expression Levels Are Associated With Peritoneal Recurrence and Poor Prognosis in Gastric Cancer

    Sasahara Masahiro, Kanda Mitsuro, Shimizu Dai, Tanaka Chie, Inokawa Yoshikuni, Hattori Norifumi, Hayashi Masamichi, Nakayama Goro, Kodera Yasuhiro

    ANTICANCER RESEARCH   Vol. 41 ( 2 ) page: 609 - 617   2021.2

  33. Tissue <i>RNFT2</i> Expression Levels Are Associated With Peritoneal Recurrence and Poor Prognosis in Gastric Cancer.

    Sasahara M, Kanda M, Shimizu D, Tanaka C, Inokawa Y, Hattori N, Hayashi M, Nakayama G, Kodera Y

    Anticancer research   Vol. 41 ( 2 ) page: 609 - 617   2021.2

  34. Age-Related Differences in the Prognosis of Pancreatic Cancer According to Perioperative Systemic Therapy

    Sonohara Fuminori, Yamada Suguru, Kurimoto Keisuke, Inokawa Yoshikuni, Takami Hideki, Hayashi Masamichi, Shimizu Dai, Hattori Norifumi, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Fujii Tsutomu, Kodera Yasuhiro

    PANCREAS   Vol. 50 ( 1 ) page: 37 - 46   2021.1

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  35. Pancreatic Fat and Body Composition Measurements by Computed Tomography are Associated with Pancreatic Fistula After Pancreatectomy

    Tanaka Katsuhito, Yamada Suguru, Sonohara Fuminori, Takami Hideki, Hayashi Masamichi, Kanda Mitsuro, Kobayashi Daisuke, Tanaka Chie, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   Vol. 28 ( 1 ) page: 530 - 538   2021.1

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  36. Newly developed primary malignancies in long-term survivors who underwent curative esophagectomy for squamous cell carcinoma of the esophagus

    Shimizu Dai, Koike Masahiko, Kanda Mitsuro, Sonohara Fuminori, Hattori Norifumi, Hayashi Masamichi, Tanaka Chie, Yamada Suguru, Kodera Yasuhiro

    SURGERY TODAY   Vol. 51 ( 1 ) page: 153 - 158   2021.1

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  37. Different Characteristics of Serum Alfa Fetoprotein and Serum Des-gamma-carboxy Prothrombin in Resected Hepatocellular Carcinoma

    Hayashi Masamichi, Yamada Suguru, Takano Nao, Okamura Yukiyasu, Takami Hideki, Inokawa Yoshikuni, Sonohara Fuminori, Tanaka Nobutake, Shimizu Dai, Hattori Norifumi, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    IN VIVO   Vol. 35 ( 3 ) page: 1749 - 1760   2021

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  38. AMIGO2 Expression as a Potential Prognostic Biomarker for Gastric Cancer

    Nakamura Shunsuke, Kanda Mitsuro, Shimizu Dai, Tanaka Chie, Inokawa Yoshikuni, Hattori Norifumi, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Omae Kenji, Koike Masahiko, Kodera Yasuhiro

    ANTICANCER RESEARCH   Vol. 40 ( 12 ) page: 6713 - 6721   2020.12

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  39. Novel Prognostic Implications of Methylated RNA and Demethylases in Resected HCC and Background Liver Tissue

    Nakagawa Nobuhiko, Tanaka Katsuhito, Sonohara Fuminori, Kandimalla Raju, Sunagawa Yuki, Inokawa Yoshikuni, Takami Hideki, Hayashi Masamichi, Yamada Suguru, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    ANTICANCER RESEARCH   Vol. 40 ( 12 ) page: 6665 - 6676   2020.12

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  40. Accurate Risk Stratification of Patients with Node-Positive Gastric Cancer by Lymph Node Ratio

    Nakamura Shunsuke, Kanda Mitsuro, Ito Seiji, Mochizuki Yoshinari, Teramoto Hitoshi, Ishigure Kiyoshi, Murai Toshifumi, Asada Takahiro, Ishiyama Akiharu, Matsushita Hidenobu, Tanaka Chie, Kobayashi Daisuke, Fujiwara Michitaka, Murotani Kenta, Kodera Yasuhiro

    WORLD JOURNAL OF SURGERY   Vol. 44 ( 12 ) page: 4184 - 4192   2020.12

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  41. AnOpen-Label Single-ArmPhaseIIStudy of Treatment with Neoadjuvant S-1 Plus Cisplatin for Clinical StageIIISquamous Cell Carcinoma of the Esophagus

    Kanda Mitsuro, Koike Masahiko, Iwata Naoki, Shimizu Dai, Tanaka Chie, Hattori Norifumi, Hayashi Masamichi, Yamada Suguru, Omae Kenji, Nakayama Goro, Kodera Yasuhiro

    ONCOLOGIST   Vol. 25 ( 11 ) page: E1650 - E1654   2020.11

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  42. D2 lymph node dissection confers little benefit on the overall survival of older patients with resectable gastric cancer: a propensity score-matching analysis of a multi-institutional dataset

    Shinozuka Takahiro, Kanda Mitsuro, Ito Seiji, Mochizuki Yoshinari, Teramoto Hitoshi, Ishigure Kiyoshi, Murai Toshifumi, Asada Takahiro, Ishiyama Akiharu, Matsushita Hidenobu, Tanaka Chie, Kobayashi Daisuke, Fujiwara Michitaka, Murotani Kenta, Kodera Yasuhiro

    SURGERY TODAY   Vol. 50 ( 11 ) page: 1434 - 1442   2020.11

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  43. Characteristics Associated with Nodal and Distant Recurrence after Curative Resection of Squamous Cell Carcinoma of the Thoracic Esophagus

    Kanda Mitsuro, Koike Masahiko, Shimizu Dai, Tanaka Chie, Hayashi Masamichi, Hattori Norifumi, Yamada Suguru, Nakayama Goro, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS   Vol. 231 ( 4 ) page: E121 - E121   2020.10

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    Language:Japanese  

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  44. Characteristics Associated with Nodal and Distant Recurrence After Radical Esophagectomy for Squamous Cell Carcinoma of the Thoracic Esophagus

    Kanda Mitsuro, Koike Masahiko, Shimizu Dai, Tanaka Chie, Hattori Norifumi, Hayashi Masamichi, Yamada Suguru, Omae Kenji, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   Vol. 27 ( 9 ) page: 3195 - 3205   2020.9

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  45. Systemic Inflammation Score as a Predictor of Pneumonia after Radical Resection of Gastric Cancer: Analysis of a Multi-Institutional Dataset

    Shoka Michita, Kanda Mitsuro, Ito Seiji, Mochizuki Yoshinari, Teramoto Hitoshi, Ishigure Kiyoshi, Murai Toshifumi, Asada Takahiro, Ishiyama Akiharu, Matsushita Hidenobu, Tanaka Chie, Kobayashi Daisuke, Fujiwara Michitaka, Murotani Kenta, Kodera Yasuhiro

    DIGESTIVE SURGERY   Vol. 37 ( 5 ) page: 401 - 410   2020.9

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  46. Therapeutic monoclonal antibody targeting of neuronal pentraxin receptor to control metastasis in gastric cancer

    Kanda Mitsuro, Shimizu Dai, Sawaki Koichi, Nakamura Shunsuke, Umeda Shinichi, Miwa Takashi, Tanaka Haruyoshi, Tanaka Chie, Hayashi Masamichi, Iguchi Yohei, Yamada Suguru, Katsuno Masahisa, Kodera Yasuhiro

    MOLECULAR CANCER   Vol. 19 ( 1 ) page: 131   2020.8

  47. The impact of cancer stem cell markers in the tissues of pancreatic ductal adenocarcinoma for prognosis after surgical resections

    Inokawa Yoshikuni, Yamada Suguru, Hayashi Masamichi, Sunagawa Yuki, Sonohara Fuminori, Takami Hideki, Hattori Norifumi, Kanda Mitsuro, Kobayashi Daisuke, Tanaka Chie, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    CANCER RESEARCH   Vol. 80 ( 16 )   2020.8

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  48. Survival times are similar among patients with peritoneal, hematogenous, and nodal recurrences after curative resections for gastric cancer

    Sawaki Koichi, Kanda Mitsuro, Ito Seiji, Mochizuki Yoshinari, Teramoto Hitoshi, Ishigure Kiyoshi, Murai Toshifumi, Asada Takahiro, Ishiyama Akiharu, Matsushita Hidenobu, Tanaka Chie, Kobayashi Daisuke, Fujiwara Michitaka, Murotani Kenta, Kodera Yasuhiro

    CANCER MEDICINE   Vol. 9 ( 15 ) page: 5392 - 5399   2020.8

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  49. KCNJ15 Expression and Malignant Behavior of Esophageal Squamous Cell Carcinoma

    Nakamura Shunsuke, Kanda Mitsuro, Koike Masahiko, Shimizu Dai, Umeda Shinichi, Hattori Norifumi, Hayashi Masamichi, Tanaka Chie, Kobayashi Daisuke, Yamada Suguru, Omae Kenji, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   Vol. 27 ( 7 ) page: 2559 - 2568   2020.7

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  50. Propensity-score-matched analysis of a multi-institutional dataset to compare postoperative complications between Billroth I and Roux-en-Y reconstructions after distal gastrectomy

    Nakanishi Koki, Kanda Mitsuro, Ito Seiji, Mochizuki Yoshinari, Teramoto Hitoshi, Ishigure Kiyoshi, Murai Toshifumi, Asada Takahiro, Ishiyama Akiharu, Matsushita Hidenobu, Shimizu Dai, Tanaka Chie, Kobayashi Daisuke, Fujiwara Michitaka, Murotani Kenta, Kodera Yasuhiro

    GASTRIC CANCER   Vol. 23 ( 4 ) page: 734 - 745   2020.7

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  51. Novel Prognostic Implications of DUPAN-2 in the Era of Initial Systemic Therapy for Pancreatic Cancer

    Sunagawa Yuki, Yamada Suguru, Sato Yusuke, Morimoto Daishi, Sonohara Fuminori, Takami Hideki, Inokawa Yoshikuni, Hayashi Masamichi, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Fujii Tsutomu, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   Vol. 27 ( 6 ) page: 2081 - 2089   2020.6

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  52. PRAME as a Potential Biomarker for Liver Metastasis of Gastric Cancer

    Baba Hayato, Kanda Mitsuro, Sawaki Koichi, Umeda Shinichi, Miwa Takashi, Shimizu Dai, Tanaka Chie, Kobayashi Daisuke, Fujiwara Michitaka, Kodera Yasuhiro, Fujii Tsutomu

    ANNALS OF SURGICAL ONCOLOGY   Vol. 27 ( 6 ) page: 2071 - 2080   2020.6

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  53. Fraser extracellular matrix complex subunit 1 promotes liver metastasis of gastric cancer

    Umeda Shinichi, Kanda Mitsuro, Miwa Takashi, Tanaka Haruyoshi, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    INTERNATIONAL JOURNAL OF CANCER   Vol. 146 ( 10 ) page: 2865 - 2876   2020.5

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  54. Clinical impact of additional therapy for residual pancreatic cancer

    Yamada Suguru, Sonohara Fuminori, Tashiro Mitsuru, Murotani Kenta, Takami Hideki, Hayashi Masamichi, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujii Tsutomu, Kodera Yasuhiro

    SURGERY TODAY   Vol. 50 ( 5 ) page: 440 - 448   2020.5

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  55. Detection of indocyanine green fluorescence to determine tumor location during laparoscopic gastrectomy for gastric cancer: Results of a prospective study

    Tanaka Chie, Kanda Mitsuro, Funasaka Kohei, Miyahara Ryoji, Murotani Kenta, Tanaka Yuri, Takeda Shigeomi, Kobayashi Daisuke, Hirooka Yoshiki, Fujiwara Michitaka, Goto Hidemi, Kodera Yasuhiro

    ASIAN JOURNAL OF ENDOSCOPIC SURGERY   Vol. 13 ( 2 ) page: 160 - 167   2020.4

  56. Exploration of Exosomal Micro RNA Biomarkers Related to Epithelial-to-Mesenchymal Transition in Pancreatic Cancer

    Sonohara Fuminori, Yamada Suguru, Takeda Shigeomi, Hayashi Masamichi, Suenaga Masaya, Sunagawa Yuki, Tashiro Mitsuru, Takami Hideki, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    ANTICANCER RESEARCH   Vol. 40 ( 4 ) page: 1843 - 1853   2020.4

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  57. Optimized Cutoff Value of Serum Squamous Cell Carcinoma Antigen Concentration Accurately Predicts Recurrence After Curative Resection of Squamous Cell Carcinoma of the Esophagus

    Kanda Mitsuro, Koike Masahiko, Shimizu Dai, Tanaka Chie, Kobayashi Daisuke, Hattori Norifumi, Hayashi Masamichi, Omae Kenji, Yamada Suguru, Nakayama Goro, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   Vol. 27 ( 4 ) page: 1233 - 1240   2020.4

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  58. Clinical Implications of Naples Prognostic Score in Patients with Resected Pancreatic Cancer

    Nakagawa Nobuhiko, Yamada Suguru, Sonohara Fuminori, Takami Hideki, Hayashi Masamichi, Kanda Mitsuro, Kobayashi Daisuke, Tanaka Chie, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   Vol. 27 ( 3 ) page: 887 - 895   2020.3

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  59. Association between Lymphovascular Invasion and Recurrence in Patients with pT1N+or pT2-3N0 Gastric Cancer: a Multi-institutional Dataset Analysis

    Fujita Keizo, Kanda Mitsuro, Ito Seiji, Mochizuki Yoshinari, Teramoto Hitoshi, Ishigure Kiyoshi, Murai Toshifumi, Asada Takahiro, Ishiyama Akiharu, Matsushita Hidenobu, Tanaka Chie, Kobayashi Daisuke, Fujiwara Michitaka, Murotani Kenta, Kodera Yasuhiro

    JOURNAL OF GASTRIC CANCER   Vol. 20 ( 1 ) page: 41 - 49   2020.3

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  60. Serum levels of ANOS1 serve as a diagnostic biomarker of gastric cancer: a prospective multicenter observational study

    Kanda Mitsuro, Suh Yun-Suhk, Park Do Joong, Tanaka Chie, Ahn Sang-Noon, Kong Seong-Ho, Lee Hyuk-Joon, Kobayashi Daisuke, Fujiwara Michitaka, Shimada Hideaki, Cho BeLong, Murotani Kenta, Kim Hyung-Ho, Yang Han-Kwang, Kodera Yasuhiro

    GASTRIC CANCER   Vol. 23 ( 2 ) page: 203 - 211   2020.3

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  61. Predictive value of the modified systemic inflammation score in patients undergoing curative resection of squamous cell carcinoma of the esophagus

    Kanda Mitsuro, Koike Masahiko, Shimizu Dai, Tanaka Chie, Kobayashi Daisuke, Sonohara Fuminori, Takami Hideki, Inokawa Yoshikuni, Hattori Norifumi, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 38 ( 4 )   2020.2

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  62. Propensity-score-matched analysis of a multi-institutional dataset to compare the postoperative complications after distal gastrectomy between Billroth I and Roux-en-Y

    Nakanishi Koki, Kanda Mitsuro, Ito Seiji, Mochizuki Yoshinari, Teramoto Hitoshi, Ishigure Kiyoshi, Mmurai Toshifumi, Asada Takahiro, Ishiyama Akiharu, Matsushita Hidenobu, Shimizu Dai, Tanaka Chie, Kobayashi Daisuke, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 38 ( 4 )   2020.2

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  63. A prospective trial to evaluate treatment effects of a beta-hydroxy-beta-methylbutyrate containing nutrient for leakage a the anastomotic site after esophagectomy

    Kanda Mitsuro, Koike Masahiko, Fukaya Masahide, Miyata Kazushi, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Murotani Kenta, Fujiwara Michitaka, Nagino Masato, Kodera Yasuhiro

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 82 ( 1 ) page: 33 - 37   2020.2

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  64. The Significance of Molecular Biomarkers on Clinical Survival Outcome Differs Depending on Colon Cancer Sidedness

    Hirabayashi Sho, Hayashi Masamichi, Nakayama Goro, Mii Shinji, Hattori Norifumi, Tanabe Hiroshi, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Yamada Suguru, Koike Masahiko, Fujiwara Michitaka, Takahashi Masahide, Kodera Yasuhiro

    ANTICANCER RESEARCH   Vol. 40 ( 1 ) page: 201 - 211   2020.1

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  65. Phase I Study of Intraperitoneal Administration of Paclitaxel Combined with S-1 Plus Cisplatin for Gastric Cancer with Peritoneal Metastasis

    Kobayashi Daisuke, Ishigami Hironori, Kanda Mitsuro, Tanaka Chie, Yamaguchi Hironori, Kitayama Joji, Kodera Yasuhiro

    ONCOLOGY   Vol. 98 ( 1 ) page: 48 - 52   2020.1

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  66. Phase II study of capecitabine plus oxaliplatin (CapOX) as adjuvant chemotherapy for locally advanced rectal cancer (CORONA II)

    Hattori Norifumi, Nakayama Goro, Uehara Keisuke, Aiba Toshisada, Ishigure Kiyoshi, Sakamoto Eiji, Tojima Yuichiro, Kanda Mitsuro, Kobayashi Daisuke, Tanaka Chie, Yamada Suguru, Koike Masahiko, Fujiwara Michitaka, Nagino Masato, Kodera Yasuhiro

    INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY   Vol. 25 ( 1 ) page: 118 - 125   2020.1

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  67. Tumor size >= 50 mm as an Independent Prognostic Factor for Patients with Stage II or III Gastric Cancer After Postoperative S-1 Monotherapy: Analysis of a Multi-institution Dataset

    Tsutsuyama Masayuki, Kanda Mitsuro, Ito Seiji, Mochizuki Yoshinari, Teramoto Hitoshi, Ishigure Kiyoshi, Murai Toshifumi, Asada Takahiro, Ishiyama Akiharu, Matsushita Hidenobu, Tanaka Chie, Kobayashi Daisuke, Fujiwara Michitaka, Murotani Kenta, Kodera Yasuhiro

    WORLD JOURNAL OF SURGERY   Vol. 44 ( 1 ) page: 194 - 201   2020.1

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  68. Prognosis After Laparoscopic Gastrectomy in Patients with Pathological Stage II or III Gastric Cancer Who Were Preoperatively Diagnosed with Clinical Stage I: Propensity Score Matching Analysis of a Multicenter Dataset

    Ito Yuki, Kanda Mitsuro, Ito Seiji, Mochizuki Yoshinari, Teramoto Hitoshi, Ishigure Kiyoshi, Murai Toshifumi, Asada Takahiro, Ishiyama Akiharu, Matsushita Hidenobu, Tanaka Chie, Kobayashi Daisuke, Fujiwara Michitaka, Murotani Kenta, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   Vol. 27 ( 1 ) page: 268 - 275   2020.1

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  69. Characteristics of Lung Metastasis as an Initial Recurrence Pattern After Curative Resection of Pancreatic Cancer

    Morimoto Daishi, Yamada Suguru, Sonohara Fuminori, Takami Hideki, Hayashi Masamichi, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Fujii Tsutomu, Kodera Yasuhiro

    PANCREAS   Vol. 49 ( 5 ) page: 699 - 705   2020

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  70. STRA6 Expression Serves as a Prognostic Biomarker of Gastric Cancer

    Nakamura Shunsuke, Kanda Mitsuro, Shimizu Dai, Sawaki Kouichi, Tanaka Chie, Hattori Norifumi, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Omae Kenji, Koike Masahiko, Kodera Yasuhiro

    CANCER GENOMICS & PROTEOMICS   Vol. 17 ( 5 ) page: 509 - 516   2020

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  71. The Preoperative Prognostic Nutritional Index Predicts Short-Term and Long-Term Outcomes of Patients with Stage II/III Gastric Cancer: Analysis of a Multi-Institution Dataset

    Sasahara Masahiro, Kanda Mitsuro, Ito Seiji, Mochizuki Yoshinari, Teramoto Hitoshi, Ishigure Kiyoshi, Murai Toshifumi, Asada Takahiro, Ishiyama Akiharu, Matsushita Hidenobu, Tanaka Chie, Kobayashi Daisuke, Fujiwara Michitaka, Murotani Kenta, Kodera Yasuhiro

    DIGESTIVE SURGERY   Vol. 37 ( 2 ) page: 135 - 144   2020

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  72. Modified Systemic Inflammation Score is Useful for Risk Stratification After Radical Resection of Squamous Cell Carcinoma of the Esophagus

    Kanda Mitsuro, Koike Masahiko, Tanaka Chie, Kobayashi Daisuke, Hattori Norifumi, Hayashi Masamichi, Yamada Suguru, Omae Kenji, Fujiwara Michitaka, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   Vol. 26 ( 13 ) page: 4773 - 4781   2019.12

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  73. Comparison of non-invasive liver reserve and fibrosis models: Implications for surgery and prognosis for hepatocellular carcinoma

    Sonohara Fuminori, Yamada Suguru, Tanaka Nobutake, Tashiro Mitsuru, Sunagawa Yuki, Morimoto Daishi, Tanaka Haruyoshi, Takami Hideki, Hayashi Masamichi, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    HEPATOLOGY RESEARCH   Vol. 49 ( 11 ) page: 1305 - 1315   2019.11

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  74. Expression, Function, and Prognostic Value of MAGE-D4 Protein in Esophageal Squamous Cell Carcinoma

    Uno Yasuo, Kanda Mitsuro, Sato Yusuke, Shimizu Dai, Umeda Shinichi, Hattori Norifumi, Hayashi Masamichi, Tanaka Chie, Kobayashi Daisuke, Yamada Suguru, Nakayama Goro, Motoyama Satoru, Koike Masahiko, Kodera Yasuhiro

    ANTICANCER RESEARCH   Vol. 39 ( 11 ) page: 6015 - 6023   2019.11

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  75. The levels of SYT13 and CEA mRNAs in peritoneal lavages predict the peritoneal recurrence of gastric cancer

    Nakanishi Koki, Kanda Mitsuro, Umeda Shinichi, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Yamada Suguru, Kodera Yasuhiro

    GASTRIC CANCER   Vol. 22 ( 6 ) page: 1143 - 1152   2019.11

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  76. Level of Melanotransferrin in Tissue and Sera Serves as a Prognostic Marker of Gastric Cancer

    Sawaki Koichi, Kanda Mitsuro, Umeda Shinichi, Miwa Takashi, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Omae Kenji, Koike Masahiko, Kodera Yasuhiro

    ANTICANCER RESEARCH   Vol. 39 ( 11 ) page: 6125 - 6133   2019.11

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  77. Tissue Expression of Melanoma-associated Antigen A6 and Clinical Characteristics of Gastric Cancer

    Endo Miyo, Kanda Mitsuro, Sawaki Koichi, Shimizu Dai, Tanaka Chie, Kobayashi Daisuke, Hattori Norifumi, Hayashi Masamichi, Yamada Suguru, Koike Masahiko, Omae Kenji, Kodera Yasuhiro

    ANTICANCER RESEARCH   Vol. 39 ( 11 ) page: 5903 - 5910   2019.11

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  78. Delay in initiation of postoperative adjuvant chemotherapy with S-1 monotherapy and prognosis for gastric cancer patients: analysis of a multi-institutional dataset

    Nakanishi Koki, Kanda Mitsuro, Ito Seiji, Mochizuki Yoshinari, Teramoto Hitoshi, Ishigure Kiyoshi, Murai Toshifumi, Asada Takahiro, Ishiyama Akiharu, Matsushita Hidenobu, Tanaka Chie, Kobayashi Daisuke, Fujiwara Michitaka, Murotani Kenta, Kodera Yasuhiro

    GASTRIC CANCER   Vol. 22 ( 6 ) page: 1215 - 1225   2019.11

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  79. Feasibility of subtotal esophagectomy with systematic lymphadenectomy in selected elderly patients with esophageal cancer; a propensity score matching analysis

    Kanda Mitsuro, Koike Masahiko, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Omae Kenji, Kodera Yasuhiro

    BMC SURGERY   Vol. 19 ( 1 ) page: 143   2019.10

  80. Novel implications of combined arterial resection for locally advanced pancreatic cancer in the era of newer chemo-regimens

    Sonohara Fuminori, Yamada Suguru, Takami Hideki, Hayashi Masamichi, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Fujii Tsutomu, Kodera Yasuhiro

    EJSO   Vol. 45 ( 10 ) page: 1895 - 1900   2019.10

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  81. Risk Prediction of Postoperative Pneumonia After Subtotal Esophagectomy Based on Preoperative Serum Cholinesterase Concentrations

    Kanda Mitsuro, Koike Masahiko, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Yamada Suguru, Omae Kenji, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   Vol. 26 ( 11 ) page: 3718 - 3726   2019.10

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  82. Biological and conditional factors should be included when defining criteria for resectability for patients with pancreatic cancer

    Kato Yoshiyasu, Yamada Suguru, Tashiro Mitsuru, Sonohara Fuminori, Takami Hideki, Hayashi Masamichi, Kanda Mitsuro, Kobayashi Daisuke, Tanaka Chie, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    HPB   Vol. 21 ( 9 ) page: 1211 - 1218   2019.9

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  83. Multi-institutional analysis of the prognostic significance of postoperative complications after curative resection for gastric cancer

    Kanda Mitsuro, Ito Seiji, Mochizuki Yoshinari, Teramoto Hitoshi, Ishigure Kiyoshi, Murai Toshifumi, Asada Takahiro, Ishiyama Akiharu, Matsushita Hidenobu, Tanaka Chie, Kobayashi Daisuke, Fujiwara Michitaka, Murotani Kenta, Kodera Yasuhiro

    CANCER MEDICINE   Vol. 8 ( 11 ) page: 5194 - 5201   2019.9

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  84. Proposal of a Scoring Scale to Estimate Risk of the Discontinuation of S-1 Adjuvant Monotherapy in Patients with Stage II to III Gastric Cancer: A Multi-Institutional Dataset Analysis

    Iizuka Akimitsu, Kanda Mitsuro, Ito Seiji, Mochizuki Yoshinari, Teramoto Hitoshi, Ishigure Kiyoshi, Murai Toshifumi, Asada Takahiro, Ishiyama Akiharu, Matsushita Hidenobu, Tanaka Chie, Kobayashi Daisuke, Fujiwara Michitaka, Murotani Kenta, Kodera Yasuhiro

    WORLD JOURNAL OF SURGERY   Vol. 43 ( 8 ) page: 2016 - 2024   2019.8

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  85. Number of retrieved lymph nodes is an independent prognostic factor after total gastrectomy for patients with stage III gastric cancer: propensity score matching analysis of a multi-institution dataset.

    Hayashi S, Kanda M, Ito S, Mochizuki Y, Teramoto H, Ishigure K, Murai T, Asada T, Ishiyama A, Matsushita H, Tanaka C, Kobayashi D, Fujiwara M, Murotani K, Kodera Y

    Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association   Vol. 22 ( 4 ) page: 853 - 863   2019.7

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    DOI: 10.1007/s10120-018-0902-2

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  86. Functions of FRAS1 as a driver gene of liver metastasis from gastric cancer analyzed by the genome editing technology

    Umeda Shinichi, Kanda Mitsuro, Tanaka Haruyoshi, Sonohara Fuminori, Takami Hideki, Hattori Norifumi, Hayashi Masamichi, Tanaka Chie, Kobayashi Daisuke, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER RESEARCH   Vol. 79 ( 13 )   2019.7

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  87. Albumin-Bilirubin Score Predicts Tolerability to Adjuvant S-1 Monotherapy after Curative Gastrectomy

    Miwa Takashi, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    JOURNAL OF GASTRIC CANCER   Vol. 19 ( 2 ) page: 183 - 192   2019.6

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  88. Homeobox C10 Influences on the Malignant Phenotype of Gastric Cancer Cell Lines and its Elevated Expression Positively Correlates with Recurrence and Poor Survival.

    Miwa T, Kanda M, Umeda S, Tanaka H, Tanaka C, Kobayashi D, Suenaga M, Hayashi M, Yamada S, Nakayama G, Koike M, Kodera Y

    Annals of surgical oncology   Vol. 26 ( 5 ) page: 1535 - 1543   2019.5

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    DOI: 10.1245/s10434-019-07166-5

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  89. Long-term quality of life and nutrition status of the aboral pouch reconstruction after total gastrectomy for gastric cancer: a prospective multicenter observational study (CCOG1505).

    Tanaka C, Kanda M, Murotani K, Yoshikawa T, Cho H, Ito Y, Matsui T, Nakayama H, Yamada T, Kobayashi D, Fujiwara M, Kodera Y

    Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association   Vol. 22 ( 3 ) page: 607 - 616   2019.5

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    DOI: 10.1007/s10120-018-0893-z

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  90. Increased Expression of DNAJC12 is Associated with Aggressive Phenotype of Gastric Cancer.

    Uno Y, Kanda M, Miwa T, Umeda S, Tanaka H, Tanaka C, Kobayashi D, Suenaga M, Hattori N, Hayashi M, Yamada S, Nakayama G, Fujiwara M, Kodera Y

    Annals of surgical oncology   Vol. 26 ( 3 ) page: 836 - 844   2019.3

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    DOI: 10.1245/s10434-018-07149-y

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  91. Intraoperative Blood Loss is Associated with Shortened Postoperative Survival of Patients with Stage II/III Gastric Cancer: Analysis of a Multi-institutional Dataset.

    Ito Y, Kanda M, Ito S, Mochizuki Y, Teramoto H, Ishigure K, Murai T, Asada T, Ishiyama A, Matsushita H, Tanaka C, Kobayashi D, Fujiwara M, Murotani K, Kodera Y

    World journal of surgery   Vol. 43 ( 3 ) page: 870 - 877   2019.3

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    DOI: 10.1007/s00268-018-4834-0

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  92. Prediction of peritoneal recurrences of gastric cancer by qPCR analysis of peritoneal lavage fluids.

    Nakanishi Koki, Kanda Mitsuro, Umeda Shinichi, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 37 ( 4 )   2019.2

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  93. The Controlling Nutritional Status Score Serves as a Predictor of Short- and Long-Term Outcomes for Patients with Stage 2 or 3 Gastric Cancer: Analysis of a Multi-institutional Data Set.

    Ryo S, Kanda M, Ito S, Mochizuki Y, Teramoto H, Ishigure K, Murai T, Asada T, Ishiyama A, Matsushita H, Tanaka C, Kobayashi D, Fujiwara M, Murotani K, Kodera Y

    Annals of surgical oncology   Vol. 26 ( 2 ) page: 456 - 464   2019.2

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    DOI: 10.1245/s10434-018-07121-w

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  94. Prognostic significance of perioperative tumor marker levels in stage II/III gastric cancer

    Suenaga Yasuhito, Kanda Mitsuro, Ito Seiji, Mochizuki Yoshinari, Teramoto Hitoshi, Ishigure Kiyoshi, Murai Toshifumi, Asada Takahiro, Ishiyama Akiharu, Matsushita Hidenobu, Tanaka Chie, Kobayashi Daisuke, Fujiwara Michitaka, Murotani Kenta, Kodera Yasuhiro

    WORLD JOURNAL OF GASTROINTESTINAL ONCOLOGY   Vol. 11 ( 1 ) page: 17 - 27   2019.1

  95. Identification of a serum-based miRNA signature for response of esophageal squamous cell carcinoma to neoadjuvant chemotherapy

    Niwa Yukiko, Yamada Suguru, Sonohara Fuminori, Kurimoto Keisuke, Hayashi Masamichi, Tashiro Mitsuru, Iwata Naoki, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF TRANSLATIONAL MEDICINE   Vol. 17 ( 1 ) page: 1   2019.1

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    DOI: 10.1186/s12967-018-1762-6

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  96. Optical trocar access for initial trocar placement in laparoscopic gastrointestinal surgery: A propensity score-matching analysis.

    Tanaka C, Fujiwara M, Kanda M, Murotani K, Iwata N, Hayashi M, Kobayashi D, Yamada S, Kodera Y

    Asian journal of endoscopic surgery   Vol. 12 ( 1 ) page: 37 - 42   2019.1

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    DOI: 10.1111/ases.12484

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  97. Perioperative and prognostic implication of albumin-bilirubin-TNM score in Child-Pugh class A hepatocellular carcinoma

    Sonohara Fuminori, Yamada Suguru, Tanaka Nobutake, Suenaga Masaya, Takami Hideki, Hayashi Masamichi, Niwa Yukiko, Sugimoto Hiroyuki, Hattori Norifumi, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    ANNALS OF GASTROENTEROLOGICAL SURGERY   Vol. 3 ( 1 ) page: 65 - 74   2019.1

  98. Establishment of Peritoneal and Hepatic Metastasis Mouse Xenograft Models Using Gastric Cancer Cell Lines

    Miwa Takashi, Kanda Mitsuro, Umeda Shinichi, Tanaka Haruyoshi, Shimizu Dai, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    IN VIVO   Vol. 33 ( 6 ) page: 1785 - 1792   2019

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  99. Peritoneal Lavage Tumor DNA as a Novel Biomarker for Predicting Peritoneal Recurrence in Pancreatic Ductal Adenocarcinoma

    Suenaga M., Fujii T., Yamada S., Hayashi M., Shinjo K., Takami H., Niwa Y., Sonohara F., Shimizu D., Kanda M., Kobayashi D., Tanaka C., Nakayama G., Koike M., Fujiwara M., Kondo Y., Kodera Y.

    PANCREAS   Vol. 48 ( 10 ) page: 1528 - 1528   2019

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  100. Integrated multigene expression panel to prognosticate patients with gastric cancer

    Kanda Mitsuro, Miwa Takashi, Umeda Shinichi, Tanaka Chie, Hayashi Masamichi, Suenaga Masaya, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER SCIENCE   Vol. 109   page: 769-769   2018.12

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  101. Homeobox C10 correlates with the malignant phenotype of gastric cancer and its recurrence and poor survival

    Miwa Takashi, Kanda Mitsuro, Tanaka Chie, Yamada Suguru, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER SCIENCE   Vol. 109   page: 1127-1127   2018.12

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  102. FRAS1 expression reflects the malignancy potential of gastric cancer

    Umeda Shinichi, Kanda Mitsuro, Tanaka Chie, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER SCIENCE   Vol. 109   page: 1128-1128   2018.12

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  103. Copine 5 expression predicts prognosis following curative resection of esophageal squamous cell carcinoma

    Umeda Shinichi, Kanda Mitsuro, Koike Masahiko, Tanaka Haruyoshi, Miwa Takashi, Tanaka Chie, Kobayashi Daisuke, Suenaga Masaya, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Kodera Yasuhiro

    ONCOLOGY REPORTS   Vol. 40 ( 6 ) page: 3772 - 3780   2018.12

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    DOI: 10.3892/or.2018.6742

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  104. A New Biomarker for Peritoneal Lavage Using Digital PCR in Patients with Pancreatic Ductal Adenocarcinoma

    Suenaga Masaya, Yamada Suguru, Hayashi Masamichi, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER SCIENCE   Vol. 109   page: 650-650   2018.12

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  105. Pathological tumor infiltrative pattern and sites of initial recurrence in stage II/III gastric cancer: Propensity score matching analysis of a multi-institutional dataset

    Nakagawa Nobuhiko, Kanda Mitsuro, Ito Seiji, Mochizuki Yoshinari, Teramoto Hitoshi, Ishigure Kiyoshi, Murai Toshifumi, Asada Takahiro, Ishiyama Akiharu, Matsushita Hidenobu, Tanaka Chie, Kobayashi Daisuke, Fujiwara Michitaka, Murotani Kenta, Kodera Yasuhiro

    CANCER MEDICINE   Vol. 7 ( 12 ) page: 6020 - 6029   2018.12

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    DOI: 10.1002/cam4.1868

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  106. Troponin I2 as a specific biomarker for prediction of peritoneal metastasis in gastric cancer

    Sawaki Koichi, Kanda Mitsuro, Suenaga Masaya, Hayashi Masamichi, Tanaka Chie, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER SCIENCE   Vol. 109   page: 765-765   2018.12

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  107. Pattern-specific Transcriptomics Identifies ASGR2 as a Predictor of Hematogenous Recurrence of Gastric Cancer

    Tanaka Haruyoshi, Kanda Mitsuro, Suenaga Masaya, Hayashi Masamichi, Tanaka Chie, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER SCIENCE   Vol. 109   page: 1128-1128   2018.12

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  108. Treatment strategy of intraperitoneal and systemic chemotherapy combined with gastrectomy for gastric cancer with peritoneal metastasis

    Kobayashi Daisuke, Kanda Mitsuro, Tanaka Chie, Sonohara Fuminori, Suenaga Masaya, Takami Hideki, Hattori Norifumi, Niwa Yukiko, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 33   page: 98-98   2018.11

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  109. Expression of sushi domain containing two reflects the malignant potential of gastric cancer

    Umeda Shinichi, Kanda Mitsuro, Miwa Takashi, Tanaka Haruyoshi, Tanaka Chie, Kobayashi Daisuke, Suenaga Masaya, Hattori Norifumi, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER MEDICINE   Vol. 7 ( 10 ) page: 5194 - 5204   2018.10

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    DOI: 10.1002/cam4.1793

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  110. Clinical Impact of Neoadjuvant Therapy on Nutritional Status in Pancreatic Cancer

    Tashiro Mitsuru, Yamada Suguru, Sonohara Fuminori, Takami Hideki, Suenaga Masaya, Hayashi Masamichi, Niwa Yukiko, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Fujii Tsutomu, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   Vol. 25 ( 11 ) page: 3365 - 3371   2018.10

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    DOI: 10.1245/s10434-018-6699-8

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  111. Significance of Preoperative Systemic Inflammation Score in Short-Term and Long-Term Outcomes of Patients with Pathological T2-4 Gastric Cancer After Radical Gastrectomy

    Sato Bin, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Iwata Naoki, Hattori Norifumi, Suenaga Masaya, Hayashi Masamichi, Yamada Suguru, Murotani Kenta, Fujiwara Michitaka, Kodera Yasuhiro

    WORLD JOURNAL OF SURGERY   Vol. 42 ( 10 ) page: 3277 - 3285   2018.10

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    DOI: 10.1007/s00268-018-4597-7

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  112. SYT7 acts as a driver of hepatic metastasis formation of gastric cancer cells

    Kanda Mitsuro, Tanaka Haruyoshi, Shimizu Dai, Miwa Takashi, Umeda Shinichi, Tanaka Chie, Kobayashi Daisuke, Hattori Norifumi, Suenaga Masaya, Hayashi Masamichi, Iwata Naoki, Yamada Suguru, Fujiwara Michitaka, Kodera Yasuhiro

    ONCOGENE   Vol. 37 ( 39 ) page: 5355 - 5366   2018.9

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    DOI: 10.1038/s41388-018-0335-8

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  113. Comparison of the Survival Outcomes of Pancreatic Cancer and Intraductal Papillary Mucinous Neoplasms.

    Yamada S, Fujii T, Hirakawa A, Takami H, Suenaga M, Hayashi M, Niwa Y, Hattori N, Iwata N, Kanda M, Tanaka C, Kobayashi D, Nakayama G, Koike M, Fujiwara M, Kodera Y

    Pancreas   Vol. 47 ( 8 ) page: 974 - 979   2018.9

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    DOI: 10.1097/MPA.0000000000001110

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  114. Pattern-Specific Transcriptomics Identifies ASGR2 as a Predictor of Hematogenous Recurrence of Gastric Cancer

    Tanaka Haruyoshi, Kanda Mitsuro, Miwa Takashi, Tanaka Chie, Kobayashi Daisuke, Umeda Shinichi, Shibata Masahiro, Suenaga Masaya, Hattori Norifumi, Hayashi Masamichi, Iwata Naoki, Yamada Suguru, Nakayama Goro, Fujiwara Michitaka, Kodera Yasuhiro

    MOLECULAR CANCER RESEARCH   Vol. 16 ( 9 ) page: 1420 - 1429   2018.9

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    DOI: 10.1158/1541-7786.MCR-17-0467

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  115. Synaptotagmin XIII expression and peritoneal metastasis in gastric cancer

    Kanda M., Shimizu D., Tanaka H., Tanaka C., Kobayashi D., Hayashi M., Takami H., Niwa Y., Yamada S., Fujii T., Sugimoto H., Kodera Y.

    BRITISH JOURNAL OF SURGERY   Vol. 105 ( 10 ) page: 1349-1358   2018.9

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    DOI: 10.1002/bjs.10876

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  116. Impact of the Controlling Nutritional Status Score on the Prognosis After Curative Resection of Pancreatic Ductal Adenocarcinoma

    Kato Yoshiyasu, Yamada Suguru, Suenaga Masaya, Takami Hideki, Niwa Yukiko, Hayashi Masamichi, Iwata Naoki, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    PANCREAS   Vol. 47 ( 7 ) page: 823 - 829   2018.8

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    DOI: 10.1097/MPA.0000000000001105

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  117. Efficacy of enteral nutrients containing beta-hydroxy-beta-methylbutyrate, glutamine, and arginine for the patients with anastomotic leakage after gastrectomy: study protocol of a multicenter phase II clinical trial

    Kanda Mitsuro, Tanaka Chie, Murotani Kenta, Kobayashi Daisuke, Ito Seiji, Mochizuki Yoshinari, Ishigure Kiyoshi, Ishiyama Akiharu, Teramoto Hitoshi, Murai Toshifumi, Asada Takahiro, Matsushita Hidenobu, Fujiwara Michitaka, Kodera Yasuhiro

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 80 ( 3 ) page: 351-355   2018.8

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    DOI: 10.18999/nagjms.80.3.351

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  118. Randomized Phase II Trial of CapOX plus Bevacizumab and CapIRI plus Bevacizumab as First-Line Treatment for Japanese Patients with Metastatic Colorectal Cancer (CCOG-1201 Study)

    Nakayama Goro, Mitsuma Ayako, Sunagawa Yuki, Ishigure Kiyoshi, Yokoyama Hiroyuki, Matsui Takanori, Nakayama Hiroshi, Nakata Kazuhiko, Ishiyama Akiharu, Asada Takahiro, Umeda Shinichi, Ezaka Kazuhiro, Hattori Norifumi, Takami Hideki, Kobayashi Daisuke, Tanaka Chie, Kanda Mitsuro, Yamada Suguru, Koike Masahiko, Fujiwara Michitaka, Fujii Tsutomu, Murotani Kenta, Ando Yuichi, Kodera Yasuhiro

    ONCOLOGIST   Vol. 23 ( 8 ) page: 919 - 927   2018.8

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    DOI: 10.1634/theoncologist.2017-0640

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  119. Troponin I2 as a Specific Biomarker for Prediction of Peritoneal Metastasis in Gastric Cancer

    Sawaki Koichi, Kanda Mitsuro, Miwa Takashi, Umeda Shinichi, Tanaka Haruyoshi, Tanaka Chie, Kobayashi Daisuke, Suenaga Masaya, Hattori Norifumi, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Fujiwara Michitaka, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   Vol. 25 ( 7 ) page: 2083 - 2090   2018.7

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    DOI: 10.1245/s10434-018-6480-z

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  120. Clinical Implications of Lysyl Oxidase-Like Protein 2 Expression in Pancreatic Cancer

    Tanaka Nobutake, Yamada Suguru, Sonohara Fuminori, Suenaga Masaya, Hayashi Masamichi, Takami Hideki, Niwa Yukiko, Hattori Norifumi, Iwata Naoki, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Fujii Tsutomu, Kodera Yasuhiro

    SCIENTIFIC REPORTS   Vol. 8 ( 1 ) page: 9846   2018.6

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    DOI: 10.1038/s41598-018-28253-9

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  121. IDENTIFICATION OF MOLECULES DRIVING HEPATIC METASTASIS FORMATION OF GASTRIC CANCER CELLS

    Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Suenaga Masaya, Takami Hideki, Hattori Norifumi, Niwa Yukiko, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    GUT   Vol. 67   page: A5-A5   2018.6

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    DOI: 10.1136/gutjnl-2018-IDDFabstracts.12

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  122. A novel dual-marker expression panel for easy and accurate risk stratification of patients with gastric cancer

    Kanda Mitsuro, Murotani Kenta, Tanaka Haruyoshi, Miwa Takashi, Umeda Shinichi, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Hattori Norifumi, Suenaga Masaya, Yamada Suguru, Nakayama Goro, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER MEDICINE   Vol. 7 ( 6 ) page: 2463 - 2471   2018.6

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    DOI: 10.1002/cam4.1522

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  123. Postoperative adalimumab maintenance therapy for Japanese patients with Crohn's disease: a single-center, single-arm phase II trial (CCOG-1107 study)

    Asada Takahiro, Nakayama Goro, Tanaka Chie, Kobayashi Daisuke, Ezaka Kazuhiro, Hattori Norifumi, Kanda Mitsuro, Yamada Suguru, Koike Masahiko, Kodera Yasuhiro

    SURGERY TODAY   Vol. 48 ( 6 ) page: 609 - 617   2018.6

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    DOI: 10.1007/s00595-018-1634-y

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  124. Significance of Lysyl oxidase-like 2 gene expression on the epithelial-mesenchymal status of hepatocellular carcinoma

    Ninomiya Go, Yamada Suguru, Hayashi Masamichi, Takeda Shigeomi, Suenaga Masaya, Takami Hideki, Kanda Mitsuro, Iwata Naoki, Niwa Yukiko, Tanaka Chie, Kobayashi Daisuke, Fujii Tsutomu, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    ONCOLOGY REPORTS   Vol. 39 ( 6 ) page: 2664 - 2672   2018.6

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    DOI: 10.3892/or.2018.6349

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  125. Integrated multigene expression panel to prognosticate patients with gastric cancer.

    Kanda M, Murotani K, Tanaka H, Miwa T, Umeda S, Tanaka C, Kobayashi D, Hayashi M, Hattori N, Suenaga M, Yamada S, Nakayama G, Fujiwara M, Kodera Y

    Oncotarget   Vol. 9 ( 27 ) page: 18775-18785   2018.4

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    DOI: 10.18632/oncotarget.24661

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  126. Preoperative Albumin-Bilirubin Grade Predicts Recurrences After Radical Gastrectomy in Patients with pT2-4 Gastric Cancer. Reviewed

    Kanda M, Tanaka C, Kobayashi D, Uda H, Inaoka K, Tanaka Y, Hayashi M, Iwata N, Yamada S, Fujii T, Sugimoto H, Murotani K, Fujiwara M, Kodera Y

    World journal of surgery   Vol. 42 ( 3 ) page: 773 - 781   2018.3

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    DOI: 10.1007/s00268-017-4234-x

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  127. Significance of SYT8 For the Detection, Prediction, and Treatment of Peritoneal Metastasis From Gastric Cancer. Reviewed

    Kanda M, Shimizu D, Tanaka H, Tanaka C, Kobayashi D, Hayashi M, Iwata N, Niwa Y, Yamada S, Fujii T, Sugimoto H, Murotani K, Fujiwara M, Kodera Y

    Annals of surgery   Vol. 267 ( 3 ) page: 495 - 503   2018.3

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    DOI: 10.1097/SLA.0000000000002096

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  128. Identification of a novel molecule target for the diagnosis, prediction, and treatment of hepatic metastasis of gastric cancer.

    Kanda Mitsuro, Tanaka Haruyoshi, Miwa Takashi, Kobayashi Daisuke, Tanaka Chie, Takami Hideki, Hayashi Masamichi, Iwata Naoki, Niwa Yukiko, Yamada Suguru, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 36 ( 4 ) page: .   2018.2

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  129. Phase I study of chemoradiotherapy using gemcitabine plus nab-paclitaxel for unresectable locally advanced pancreatic cancer.

    Yamada Suguru, Fujii Tsutomu, Takano Nao, Takami Hideki, Suenaga Masaya, Niwa Yukiko, Hayashi Masamichi, Iwata Naoki, Kanda Mitsuro, Kobayashi Daisuke, Tanaka Chie, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 36 ( 4 ) page: .   2018.2

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  130. Clinical implication of nutrition for neoadjuvant therapy and impact of nutritional support in pancreatic cancer.

    Tashiro Mitsuru, Yamada Suguru, Fujii Tsutomu, Hattori Norifumi, Takami Hideki, Suenaga Masaya, Niwa Yukiko, Hayashi Masamichi, Iwata Naoki, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 36 ( 4 )   2018.2

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  131. Oncogenic function of miR-23b-3p in hepatocellular carcinoma

    Masamichi Hayashi, Yamada Suguru, Kanda Mitsuro, Tanaka Chie, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER SCIENCE   Vol. 109   page: 1123-1123   2018.1

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  132. Perioperative Serum Carcinoembryonic Antigen Levels Predict Recurrence and Survival of Patients with Pathological T2-4 Gastric Cancer Treated with Curative Gastrectomy. Reviewed

    Uda H, Kanda M, Tanaka C, Kobayashi D, Inaoka K, Tanaka Y, Hayashi M, Iwata N, Yamada S, Fujii T, Sugimoto H, Murotani K, Fujiwara M, Kodera Y

    Digestive surgery   Vol. 35 ( 1 ) page: 55 - 63   2018

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    DOI: 10.1159/000471931

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  133. Nutritional Recovery after Open and Laparoscopic Distal Gastrectomy for Early Gastric Cancer: A Prospective Multicenter Comparative Trial (CCOG1204). Reviewed

    Matsushita H, Tanaka C, Murotani K, Misawa K, Ito S, Ito Y, Kanda M, Mochizuki Y, Ishigure K, Yaguchi T, Teramoto J, Nakayama H, Kawase Y, Fujiwara M, Kodera Y

    Digestive surgery   Vol. 35 ( 1 ) page: 11 - 18   2018

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    DOI: 10.1159/000458714

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  134. Prognostic Impact of Portal System Invasion in Pancreatic Cancer Based on Image Classification

    Morimoto Daishi, Yamada Suguru, Murotani Kenta, Sonohara Fuminori, Takami Hideki, Suenaga Masaya, Hayashi Masamichi, Niwa Yukiko, Tashiro Mitsuru, Hattori Norifumi, Iwata Naoki, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Fujii Tsutomu, Kodera Yasuhiro

    PANCREAS   Vol. 47 ( 10 ) page: 1350 - 1356   2018

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    DOI: 10.1097/MPA.0000000000001186

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  135. FBXO50 Enhances the Malignant Behavior of Gastric Cancer Cells. Reviewed

    Miwa T, Kanda M, Tanaka H, Tanaka C, Kobayashi D, Umeda S, Iwata N, Hayashi M, Yamada S, Fujii T, Fujiwara M, Kodera Y

    Annals of surgical oncology   Vol. 24 ( 12 ) page: 3771 - 3779   2017.11

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    DOI: 10.1245/s10434-017-5882-7

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  136. Identification of <i>NCCRP1</i> as an epigenetically regulated tumor suppressor and biomarker for malignant phenotypes of squamous cell carcinoma of the esophagus. Reviewed

    Miwa T, Kanda M, Koike M, Iwata N, Tanaka H, Umeda S, Tanaka C, Kobayashi D, Hayashi M, Yamada S, Fujii T, Fujiwara M, Kodera Y

    Oncology letters   Vol. 14 ( 4 ) page: 4822 - 4828   2017.10

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    DOI: 10.3892/ol.2017.6753

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  137. Evaluation and proposal of novel resectability criteria for pancreatic cancer established by the Japan Pancreas Society. Reviewed

    Yamada S, Fujii T, Takami H, Hayashi M, Iwata N, Kanda M, Tanaka C, Sugimoto H, Nakayama G, Koike M, Fujiwara M, Kodera Y

    Surgery   Vol. 162 ( 4 ) page: 784 - 791   2017.10

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    DOI: 10.1016/j.surg.2017.04.023

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  138. FAM46C Serves as a Predictor of Hepatic Recurrence in Patients with Resectable Gastric Cancer. Reviewed

    Tanaka H, Kanda M, Shimizu D, Tanaka C, Kobayashi D, Hayashi M, Iwata N, Yamada S, Fujii T, Nakayama G, Sugimoto H, Fujiwara M, Niwa Y, Kodera Y

    Annals of surgical oncology   Vol. 24 ( 11 ) page: 3438 - 3445   2017.10

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    DOI: 10.1245/s10434-016-5636-y

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  139. An integrated multigene expression panel to predict long-term survival after curative hepatectomy in patients with hepatocellular carcinoma. Reviewed

    Kanda M, Murotani K, Sugimoto H, Miwa T, Umeda S, Suenaga M, Hayashi M, Hattori N, Tanaka C, Kobayashi D, Yamada S, Fujiwara M, Kodera Y

    Oncotarget   Vol. 8 ( 41 ) page: 71070 - 71079   2017.9

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    DOI: 10.18632/oncotarget.20369

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  140. Downregulation of GPR155 as a prognostic factor after curative resection of hepatocellular carcinoma. Reviewed

    Umeda S, Kanda M, Sugimoto H, Tanaka H, Hayashi M, Yamada S, Fujii T, Takami H, Niwa Y, Iwata N, Tanaka C, Kobayashi D, Fujiwara M, Kodera Y

    BMC cancer   Vol. 17 ( 1 ) page: 610   2017.9

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    DOI: 10.1186/s12885-017-3629-2

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  141. Involvement of the immunoregulator MZB1 in progression of gastric cancer

    Tanaka Y., Kanda M., Tanaka C., Kobayashi D., Tanaka H., Takami H., Hayashi M., Iwata N., Niwa Y., Yamada S., Nakayama G., Sugimoto H., Koike M., Fujiwara M., Kodera Y.

    ANNALS OF ONCOLOGY   Vol. 28   page: .   2017.9

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  142. Nutritional recovery after open and laparoscopic distal gastrectomy for early gastric cancer: A prospective multicenter comparative trial (CCOG1204)

    Tanaka C., Kanda M., Misawa K., Ito S., Ito Y., Mochizuki Y., Ishigure K., Yaguchi T., Teramoto J., Nakayama H., Kawase Y., Fujiwara M., Kodera Y.

    ANNALS OF ONCOLOGY   Vol. 28   2017.9

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  143. Usefulness of preoperative estimated glomerular filtration rate to predict complications after curative gastrectomy in patients with clinical T2-4 gastric cancer. Reviewed

    Tanaka Y, Kanda M, Tanaka C, Kobayashi D, Mizuno A, Iwata N, Hayashi M, Niwa Y, Takami H, Yamada S, Fujii T, Nakayama G, Sugimoto H, Fujiwara M, Kodera Y

    Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association   Vol. 20 ( 4 ) page: 736 - 743   2017.7

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    DOI: 10.1007/s10120-016-0657-6

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  144. Stapling an extracorporeal Billroth-I anastomosis by the complete double stapling technique after laparoscopy-assisted distal gastrectomy. Reviewed

    Tanaka C, Fujiwara M, Kanda M, Murotani K, Iwata N, Hayashi M, Kobayashi D, Yamada S, Nakayama G, Sugimoto H, Koike M, Fujii T, Kodera Y

    Asian journal of endoscopic surgery   Vol. 10 ( 2 ) page: 137 - 142   2017.5

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    DOI: 10.1111/ases.12357

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  145. Intraperitoneal Administration of Plasma-Activated Medium: Proposal of a Novel Treatment Option for Peritoneal Metastasis From Gastric Cancer. Reviewed

    Takeda S, Yamada S, Hattori N, Nakamura K, Tanaka H, Kajiyama H, Kanda M, Kobayashi D, Tanaka C, Fujii T, Fujiwara M, Mizuno M, Hori M, Kodera Y

    Annals of surgical oncology   Vol. 24 ( 5 ) page: 1188 - 1194   2017.5

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    DOI: 10.1245/s10434-016-5759-1

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  146. Clinical utility of the platelet-lymphocyte ratio as a predictor of postoperative complications after radical gastrectomy for clinical T2-4 gastric cancer. Reviewed

    Inaoka K, Kanda M, Uda H, Tanaka Y, Tanaka C, Kobayashi D, Takami H, Iwata N, Hayashi M, Niwa Y, Yamada S, Fujii T, Sugimoto H, Murotani K, Fujiwara M, Kodera Y

    World journal of gastroenterology   Vol. 23 ( 14 ) page: 2519 - 2526   2017.4

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    DOI: 10.3748/wjg.v23.i14.2519

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  147. The efficacy and safety of CapeOX plus bevacizumab therapy followed by capecitabine plus bevacizumab maintenance therapy in patients with metastatic colorectal cancer: a multi-center, single-arm, phase II study (CCOG-0902). Reviewed

    Nakayama G, Ishigure K, Yokoyama H, Uehara K, Kojima H, Ishiyama A, Hayashi N, Takano N, Hattori N, Kobayashi D, Tanaka C, Hayashi M, Kanda M, Yamada S, Sugimoto H, Koike M, Fujiwara M, Fujii T, Murotani K, Ando Y, Kodera Y

    BMC cancer   Vol. 17 ( 1 ) page: 243   2017.4

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    DOI: 10.1186/s12885-017-3245-1

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  148. Clinical impact of sarcopenia on prognosis in pancreatic ductal adenocarcinoma: A retrospective cohort study. Reviewed

    Ninomiya G, Fujii T, Yamada S, Yabusaki N, Suzuki K, Iwata N, Kanda M, Hayashi M, Tanaka C, Nakayama G, Sugimoto H, Koike M, Fujiwara M, Kodera Y

    International journal of surgery (London, England)   Vol. 39   page: 45 - 51   2017.3

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    DOI: 10.1016/j.ijsu.2017.01.075

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  149. GPR155 Serves as a Predictive Biomarker for Hematogenous Metastasis in Patients with Gastric Cancer. Reviewed

    Shimizu D, Kanda M, Tanaka H, Kobayashi D, Tanaka C, Hayashi M, Iwata N, Niwa Y, Takami H, Yamada S, Fujii T, Nakayama G, Fujiwara M, Kodera Y

    Scientific reports   Vol. 7   page: 42089   2017.2

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    DOI: 10.1038/srep42089

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  150. Clinical impact of sarcopenia on prognosis in pancreatic ductal adenocarcinoma.

    Ninomiya Go, Fujii Tsutomu, Yamada Suguru, Asano Tomonari, Takano Nao, Takami Hideki, Iwata Naoki, Kanda Mitsuro, Niwa Yukiko, Hayashi Masamichi, Kobayashi Daisuke, Tanaka Chie, Nakayama Goro, Sugimoto Hiroyuki, Fujiwara Michitaka, Koike Masahiko, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 35 ( 4 )   2017.2

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  151. Clinical implication of inflammation-based prognostic score and perioperative nutrition control in pancreatic cancer.

    Takano Nao, Yamada Suguru, Fujii Tsutomu, Tashiro Mitsuru, Tanaka Nobutake, Morimoto Daishi, Ninomiya Go, Niwa Yukiko, Takami Hideki, Iwata Naoki, Hayashi Masamichi, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 35 ( 4 )   2017.2

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  152. Conversion surgery for unresectable gastric cancer following complete response of distant metastasis by systemic chemotherapy.

    Kobayashi Daisuke, Kanda Mitsuro, Tanaka Chie, Iwata Naoki, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujii Tsutomu, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 35 ( 4 )   2017.2

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  153. Tumor infiltrative pattern predicts sites of recurrence after curative gastrectomy for gastric cancer.

    Kanda Mitsuro, Kobayashi Daisuke, Tanaka Chie, Yamada Suguru, Fujii Tsutomu, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 35 ( 4 )   2017.2

  154. The protein arginine methyltransferase 5 promotes malignant phenotype of hepatocellular carcinoma cells and is associated with adverse patient outcomes after curative hepatectomy. Reviewed

    Shimizu D, Kanda M, Sugimoto H, Shibata M, Tanaka H, Takami H, Iwata N, Hayashi M, Tanaka C, Kobayashi D, Yamada S, Nakayama G, Koike M, Fujiwara M, Fujii T, Kodera Y

    International journal of oncology   Vol. 50 ( 2 ) page: 381 - 386   2017.2

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    DOI: 10.3892/ijo.2017.3833

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  155. Proposal of the Coagulation Score as a Predictor for Short-Term and Long-Term Outcomes of Patients with Resectable Gastric Cancer. Reviewed

    Kanda M, Tanaka C, Kobayashi D, Mizuno A, Tanaka Y, Takami H, Iwata N, Hayashi M, Niwa Y, Yamada S, Fujii T, Sugimoto H, Murotani K, Fujiwara M, Kodera Y

    Annals of surgical oncology   Vol. 24 ( 2 ) page: 502 - 509   2017.2

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    DOI: 10.1245/s10434-016-5544-1

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  156. PAX5 gene as a novel methylation marker that predicts both clinical outcome and cisplatin sensitivity in esophageal squamous cell carcinoma. Reviewed

    Kurimoto K, Hayashi M, Guerrero-Preston R, Koike M, Kanda M, Hirabayashi S, Tanabe H, Takano N, Iwata N, Niwa Y, Takami H, Kobayashi D, Tanaka C, Yamada S, Nakayama G, Sugimoto H, Fujii T, Fujiwara M, Kodera Y

    Epigenetics   Vol. 12 ( 10 ) page: 865 - 874   2017

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    DOI: 10.1080/15592294.2017.1365207

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  157. Prognostic relevance of <i>SAMSN1</i> expression in gastric cancer. Reviewed

    Kanda M, Shimizu D, Sueoka S, Nomoto S, Oya H, Takami H, Ezaka K, Hashimoto R, Tanaka Y, Kobayashi D, Tanaka C, Yamada S, Fujii T, Nakayama G, Sugimoto H, Koike M, Fujiwara M, Kodera Y

    Oncology letters   Vol. 12 ( 6 ) page: 4708-4716   2016.12

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    DOI: 10.3892/ol.2016.5233

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  158. Epigenetic suppression of the immunoregulator MZB1 is associated with the malignant phenotype of gastric cancer. Reviewed

    Kanda M, Tanaka C, Kobayashi D, Tanaka H, Shimizu D, Shibata M, Takami H, Hayashi M, Iwata N, Niwa Y, Yamada S, Fujii T, Nakayama G, Fujiwara M, Kodera Y

    International journal of cancer   Vol. 139 ( 10 ) page: 2290-8   2016.11

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    DOI: 10.1002/ijc.30286

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  159. Modified two-dimensional response as surrogate marker of overall survival in patients with metastatic colorectal cancer. Reviewed

    Nakayama G, Fujii T, Murotani K, Uehara K, Hattori N, Hayashi M, Tanaka C, Kobayashi D, Kanda M, Yamada S, Sugimoto H, Koike M, Fujiwara M, Ando Y, Kodera Y

    Cancer science   Vol. 107 ( 10 ) page: 1492-1498   2016.10

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    DOI: 10.1111/cas.13023

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  160. Predictive value of drain amylase content for peripancreatic inflammatory fluid collections after laparoscopic (assisted) distal gastrectomy. Reviewed

    Kanda M, Fujiwara M, Tanaka C, Kobayashi D, Iwata N, Mizuno A, Yamada S, Fujii T, Nakayama G, Sugimoto H, Koike M, Kodera Y

    Surgical endoscopy   Vol. 30 ( 10 ) page: 4353-62   2016.10

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    DOI: 10.1007/s00464-016-4753-9

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  161. Protein arginine methyltransferase 5 is associated with malignant phenotype and peritoneal metastasis in gastric cancer. Reviewed

    Kanda M, Shimizu D, Fujii T, Tanaka H, Shibata M, Iwata N, Hayashi M, Kobayashi D, Tanaka C, Yamada S, Nakayama G, Sugimoto H, Koike M, Fujiwara M, Kodera Y

    International journal of oncology   Vol. 49 ( 3 ) page: 1195-202   2016.9

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    DOI: 10.3892/ijo.2016.3584

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  162. Neurotrophin Receptor-Interacting Melanoma Antigen-Encoding Gene Homolog is Associated with Malignant Phenotype of Gastric Cancer. Reviewed

    Kanda M, Shimizu D, Fujii T, Tanaka H, Tanaka Y, Ezaka K, Shibata M, Takami H, Hashimoto R, Sueoka S, Iwata N, Kobayashi D, Tanaka C, Yamada S, Nakayama G, Sugimoto H, Koike M, Fujiwara M, Kodera Y

    Annals of surgical oncology   Vol. 23 ( Suppl 4 ) page: 532-539   2016.8

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    DOI: 10.1245/s10434-016-5375-0

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  163. Nutritional predictors for postoperative short-term and long-term outcomes of patients with gastric cancer. Reviewed

    Kanda M, Mizuno A, Tanaka C, Kobayashi D, Fujiwara M, Iwata N, Hayashi M, Yamada S, Nakayama G, Fujii T, Sugimoto H, Koike M, Takami H, Niwa Y, Murotani K, Kodera Y

    Medicine   Vol. 95 ( 24 ) page: e3781   2016.6

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    DOI: 10.1097/MD.0000000000003781

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  164. Tumor Infiltrative Pattern Predicts Sites of Recurrence After Curative Gastrectomy for Stages 2 and 3 Gastric Cancer. Reviewed

    Kanda M, Mizuno A, Fujii T, Shimoyama Y, Yamada S, Tanaka C, Kobayashi D, Koike M, Iwata N, Niwa Y, Hayashi M, Takami H, Nakayama G, Sugimoto H, Fujiwara M, Kodera Y

    Annals of surgical oncology   Vol. 23 ( 6 ) page: 1934-40   2016.6

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    DOI: 10.1245/s10434-016-5102-x

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  165. Clinical Implication of Inflammation-Based Prognostic Score in Pancreatic Cancer: Glasgow Prognostic Score Is the Most Reliable Parameter. Reviewed

    Yamada S, Fujii T, Yabusaki N, Murotani K, Iwata N, Kanda M, Tanaka C, Nakayama G, Sugimoto H, Koike M, Fujiwara M, Kodera Y

    Medicine   Vol. 95 ( 18 ) page: e3582   2016.5

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    DOI: 10.1097/MD.0000000000003582

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  166. Metastatic pathway-specific transcriptome analysis identifies MFSD4 as a putative tumor suppressor and biomarker for hepatic metastasis in patients with gastric cancer. Reviewed

    Kanda M, Shimizu D, Tanaka H, Shibata M, Iwata N, Hayashi M, Kobayashi D, Tanaka C, Yamada S, Fujii T, Nakayama G, Sugimoto H, Koike M, Fujiwara M, Kodera Y

    Oncotarget   Vol. 7 ( 12 ) page: 13667-79   2016.3

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    DOI: 10.18632/oncotarget.7269

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  167. S-1 plus nab-paclitaxel is a promising regimen for pancreatic cancer in a preclinical model. Reviewed

    Suenaga M, Yamada S, Fujii T, Tanaka C, Kanda M, Nakayama G, Sugimoto H, Koike M, Fujiwara M, Kodera Y

    Journal of surgical oncology   Vol. 113 ( 4 ) page: 413-9   2016.3

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    DOI: 10.1002/jso.24147

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  168. NRAGE promotes the malignant phenotype of hepatocellular carcinoma. Reviewed

    Shimizu D, Kanda M, Sugimoto H, Sueoka S, Takami H, Ezaka K, Tanaka Y, Hashimoto R, Okamura Y, Iwata N, Tanaka C, Yamada S, Fujii T, Nakayama G, Koike M, Nomoto S, Fujiwara M, Kodera Y

    Oncology letters   Vol. 11 ( 3 ) page: 1847-1854   2016.3

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    DOI: 10.3892/ol.2016.4120

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  169. Short-term outcomes after conventional transthoracic esophagectomy. Reviewed

    Niwa Y, Koike M, Hattori M, Iwata N, Takami H, Hayashi M, Kanda M, Kobayashi D, Tanaka C, Yamada S, Fujii T, Nakayama G, Sugimoto H, Nomoto S, Fujiwara M, Kodera Y

    Nagoya journal of medical science   Vol. 78 ( 1 ) page: 69-78   2016.2

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  170. Adverse Effects of Intraoperative Blood Loss on Long-Term Outcomes after Curative Gastrectomy of Patients with Stage II/III Gastric Cancer. Reviewed

    Mizuno A, Kanda M, Kobayashi D, Tanaka C, Iwata N, Yamada S, Fujii T, Nakayama G, Sugimoto H, Koike M, Fujiwara M, Kodera Y

    Digestive surgery   Vol. 33 ( 2 ) page: 121-8   2016

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    DOI: 10.1159/000443219

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  171. Current Options for the Diagnosis, Staging and Therapeutic Management of Colorectal Cancer. Reviewed

    Nakayama G, Tanaka C, Kodera Y

    Gastrointestinal tumors   Vol. 1 ( 1 ) page: 25-32   2013.9

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    DOI: 10.1159/000354995

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▼display all

Books 3

  1. 【早わかり縫合・吻合のすべて】(4章)術式別の縫合・吻合法 胃 噴門側胃切除術 ダブルトラクト再建での残胃-空腸吻合 腹腔鏡下

    田中 千恵, 清水 大, 小寺 泰弘( Role: Sole author)

    臨床外科   2020.10 

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    Responsible for pages:145-148   Language:Japanese Book type:Scholarly book

  2. 【解剖学的変異を考慮した上部消化管手術】局所微細解剖からみた幽門下リンパ節郭清のコツ 腹腔鏡手術を中心に

    田中 千恵, 佐藤 敏, 神田 光郎, 清水 大, 小寺 泰弘( Role: Sole author)

    手術  2020.8 

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    Responsible for pages:1339-1346   Language:Japanese Book type:Scholarly book

  3. 【若手外科医必携!-緊急手術の適応と術式】疾患別の対処法 胃十二指腸出血に対する緊急治療

    田中 千恵, 小寺 泰弘( Role: Sole author)

    臨床外科   2020.7 

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    Responsible for pages:812-817   Language:Japanese Book type:Scholarly book

KAKENHI (Grants-in-Aid for Scientific Research) 15

  1. 臓器嗜好性に焦点をあてた食道癌転移の分子機序解明からの創薬研究

    Grant number:21K19525  2021.7 - 2024.3

    科学研究費助成事業  挑戦的研究(萌芽)

    小寺 泰弘, 神田 光郎, 田中 千恵, 清水 大

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    食道癌転移経路特異的Transcriptome解析により、申請者らの仮説に一致して血行性転移群とリンパ行性転移で発現パターンが明瞭に異なるクラスターがあることが示され、血行性転移関連5分子(VWA5B2、CFAP47、NECAB2、SYCE3、RPL3L)、リンパ行性転移関連3分子(C1QL4、CCDC87、CAMK2N2)を厳選している。
    これらの食道癌転移形式別関連分子の機能解析・発現解析を行うことで、食道癌転移の分子生物学的機序の解明を通じ、食道癌予後を劇的に改善しうる分子標的治療薬と、その奏効度を事前に予測しうるコンパニオン診断法開発の基盤となるデータを得ることを目的とする。

  2. 細胞接着因子を標的とするデュアル修飾型アンチセンス核酸を用いた革新的癌治療薬創出

    Grant number:21H02984  2021.4 - 2025.3

    科学研究費助成事業  基盤研究(B)

    小寺 泰弘, 神田 光郎, 笠原 勇矢, 田中 千恵, 清水 大, 小比賀 聡

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    本研究では、細胞接着因子を標的としたアンチセンス核酸医薬による新たな胃癌分子標的治療薬およびコンパニオン診断技術開発を目指して、以下を実施する。
    1) アンチセンス核酸スクリーニング、2) メカニズム解明(機能解析、シグナル解析、KOマウス解析、正常組織中発現解析)、3) in vitro活性評価(濃度依存性の活性、癌種横断的活性評価)、4) in vivo活性評価(皮下腫瘍モデル、同所移植モデルでの薬効評価)、5) 毒性評価とオフターゲット探索、6) コンパニオン診断(治療前生検、手術検体での免疫染色法による発現解析)

  3. 高齢消化器癌手術症例における術後自立度低下に関するリスク評価と介入の有効性の検討

    Grant number:21K11620  2021.4 - 2024.3

    科学研究費助成事業  基盤研究(C)

    田中 千恵, 神田 光郎, 渡邊 一久, 小寺 泰弘, 室谷 健太, 栗本 景介, 藤原 道隆

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    Authorship:Principal investigator 

    Grant amount:\4160000 ( Direct Cost: \3200000 、 Indirect Cost:\960000 )

    本研究は,消化器癌における様々な術式の自立度への影響と複数の診療科を含む多職種横断的な介入の効果を包括的に把握し,高齢者に対する癌治療のエビデンス構築の一助となるデータを構築することを目的とする。まず,術前後の自立度の変化について調査票と血清バイオマーカー値の両面から評価する。次に,自立度が低下する患者については,老年科専門医・リハビリテーション・栄養サポートチームによる介入で機能維持を図り,ひいては,事前に自立度が低下する群を予測し,予防的介入が可能となることを見込む。

  4. Development of amido-bridged nucleic acid-modified antisense oligonucleotides to treat gastrointestinal malignancies

    Grant number:20K21629  2020.7 - 2022.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Challenging Research (Exploratory)

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  5. Development of monoclonal antibody targeting CHRNB2 to treat gastric cancer

    Grant number:20H03750  2020.4 - 2024.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)

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  6. Multi-omics analysis to identify predictors for treatment efficacy of perioperative chemotherapy in advanced gastric cancer

    Grant number:19K22653  2019.6 - 2021.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Challenging Research (Exploratory)

    KODERA Yasuhiro

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    As a pivotal clinical trial for development of treatment strategy for clinical stage III gastric cancer, a multicenter, randomized phase III clinical trial to confirm the superiority of addition of preoperative adjuvant chemotherapy with S-1 + oxaliplatin (SOX) over standard treatment is ongoing. If the efficacy of chemotherapy can be predicted before decision making of treatment, physicians can select the most appropriate treatment method for each patient, which will have great significance not only in terms of treatment effect but also in terms of medical economics. In this study, we performed a multi-omics analysis and identified candidate markers for the efficacy of preoperative SOX therapy in plasma samples (protein and microRNA). Moreover, we confirmed the feasibility of the Cancer Panel using endoacopic biopsy FFPE samples. The results of this study will greatly enhance the quality of a future biomarker study.

  7. 食道癌に対する新たな抗体医薬とコンパニオン診断技術の開発研究

    Grant number:19K09140  2019.4 - 2022.3

    科学研究費助成事業  基盤研究(C)

    小池 聖彦, 田中 千恵, 小林 大介, 神田 光郎, 澤木 康一, 小寺 泰弘

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    多様な進展経路を持つ食道癌は男女ともに癌死亡者数が増加しており、その克服は重要な課題である。食道癌の治療成績を改善するには、病態解明と分子標的治療薬開発につながる新規関連分子の同定が望まれる。本研究では、食道扁平上皮癌の細胞株と組織マイクロアレイで高頻度に発現亢進するレセプター分子を探索し同定したレセプターNに着目し、治療の奏効度を予測するコンパニオン診断法の確立と並行して研究を進める。本研究計画の目的は食道癌におけるレセプターNの機能を明らかにし、これを標的とした創薬ならびに診断法の開発に繋げることである。
    食道癌は多様な進展経路を持つ予後不良な疾患であり、本邦において男女ともに癌死亡者数が増加している。従来の殺細胞性抗腫瘍剤のコンプライアンスが得られにくく効果も限定的であるため、治療成績改善のためには治療選択肢を拡大させうる分子標的治療薬の開発が望まれている。我々は、既存の分子標的治療薬とは全く異なる標的としてneuronal pentraxin receptor (NPTXR) を同定し、これに対する特異的抗体医薬開発の糸口をつかむことを目的に本研究を進めている。また同時に、個別化治療の実現に向けて重要な、奏効度を事前に予測しうるコンパニオン診断法開発に向けてのデータ構築を行っていく。shRNAを用いた安定的NPTXRノックダウン食道扁平上皮癌細胞株を樹立し、細胞機能解析を行ったところ、癌進展に重要な細胞増殖能、浸潤能が有意に低下することを明らかにした。また、NPTXRノックダウンにより食道癌のkey drugである5-FUの感受性が改善することも発見した。抗原性・親水性予測に基づいて抗NTPXR抗体を取得した。NPTXRの悪性腫瘍における役割には未知の部分が大きく、どのようなsignaling pathwayとの干渉を有するのかを知ることは、その特性を理解するために重要である。Antibody arrayを用いて親株と安定的NPTXRノックダウン株における細胞内signaling pathwayのリン酸化について網羅的に比較したところ、Akt-mTORのシグナルのリン酸化がNPTXRにより抑制されていた。引き続き研究計画にもとづいて、食道扁平上皮癌細胞におけるNPTXRの機能解析、抗腫瘍剤感受性への影響、癌関連主要pathwayへの干渉、抗NPTXR抗体の食道癌全身転移モデル治療効果の評価、コンパニオン診断薬開発のための臨床検体中NPTXR発現解析を進めていく。
    樹立したshRNAを用いた安定的NPTXRノックダウン食道扁平上皮癌細胞株を用いて、細胞機能解析(細胞増殖能、浸潤能)を実施した。さらに、薬剤感受性への影響を調べるべく、NPTXRノックダウンの有無によるFUの感受性変化についても検討した。次年度に活性評価を行う予定の抗NTPXR抗体を取得した。シグナル解析の入り口となる網羅的細胞内signaling pathwayリン酸化解析を実施し、Akt-mTORのシグナルのリン酸化がNPTXRにより抑制されていることを発見した。おおむね研究計画に沿って進捗している。
    引き続き、shRNAによる安定的ノックダウン株を用いて癌細胞機能の変化を調べる。親株とノックダウン株の間でアポトーシス細胞比、ミトコンドリア膜電位活性、Caspase活性、細胞周期の変化を調べるととともに、癌の転移進展に重要な遊走能、接着能を順次評価していく。in vivo実験として、マウス皮下腫瘍モデルでの造腫瘍能を比較する。親株と安定的レセプターNノックダウン株の間で食道癌のkey drugであるCDDPの感受性をWST-8法で比較する。シグナル解析として、Akt-mTORシグナルに着目して関連分子のリン酸化をWestern blotting法で調査する。抗NPTXR抗体の食道癌細胞増殖抑制効果を調べる。コンパニオン診断薬開発に向けて、食道癌原発巣組織中発現と臨床データの相関解析を行う。取得したデータをまとめ、英文論文執筆を開始する。

  8. 介入による消化器癌周術期高齢者機能の改善と機能低下に影響するバイオマーカー探索

    Grant number:17K01841  2017.4 - 2021.3

    田中 千恵

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    Authorship:Principal investigator 

    Grant amount:\4550000 ( Direct Cost: \3500000 、 Indirect Cost:\1050000 )

    一昨年の解析結果をまとめると、胃癌に対する胃切除を施行した症例において、自立度、錯乱、認知機能は術前の平均スコアと比較して、退院時の平均スコアのみでなく術後6ヶ月もスコアは低下していなかった。さらに退院時に自立度が低下した症例を対象として低下の予測因子を調査したところ、年齢、性別、胃全摘術、せん妄は関連を認めなかった。しかし、術後合併症の有無(p=0.0326)が自立度低下の予測因子としてあげられた。術前と比較した退院時の認知機能低下は40例中7例(18例)に認められた。
    本研究においてMMSEやCDR-Jといった認知機能の評価は専門医である老年科医師により行われている。現実問題として、これらの評価を周術期に外科医が行うことは困難である上に、専門医による認知機能の評価がどの病院でも常時可能であるとは言えない。我々は認知機能低下症例におけるバイオマーカーを含めた予測因子の探索を行った。
    まずは術前と比較して退院時にMMSEスコアが低下した症例を対象に、臨床病理学的な予測因子の有無を調査したところ、術後せん妄を認めた症例(p=0.1890)、術後在院日数が本研究の平均値である19日を超える症例(p=0.0751)、Clavien-Dindo分類II以上の術後合併症を発症した症例(p=0.0498)であった。以上より、術後合併症を発生した症例はMMSEスコアが有意に低下していたことがわかった。術前IL-6・アディポネクチン・レジスチンの値と術後MMSE低下に明らかな関連は認めなかった。術後CDR-Jスコアの悪化と上記の各因子との間に関連は認めなかった。
    以上より、認知機能の低下と関連するバイオマーカーは見いだせていないが、術後合併症の発生は、自立度のみでなく認知機能の低下に影響する可能性があると考えられた。
    症例集積に時間を要した。しかし、昨年度で高齢者機能評価の測定とバイオマーカー測定は概ね終了した。今後は成果報告を行う。
    成果報告を行うために1年延長した。
    今後は学会、英語論文での成果報告を進めたい。
    さらに、サルコペニアやサルコペニア症例に対する手術の影響などより詳細な解析を進める。バイオマーカー探索も続ける予定である。

  9. Molecule target for treatment and companion diagnostic tool of peritoneal dissemination in gastric cancer

    Grant number:17H04281  2017.4 - 2020.3

    KODERA Yasuhiro

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    Authorship:Coinvestigator(s) 

    Peritoneal metastasis is a frequent cause of death in patients with gastric cancer. The pathophysiology and thus targets for treatment are unknown. Synaptotagmin XIII (SYT13) was expressed in patients with peritoneal recurrence of gastric cancer. Inhibition of SYT13 expression in gastric cancer cell lines was associated with decreased invasion and migration ability of the cells. In vivo experiments using a mouse xenograft model of gastric cancer showed that intraperitoneal administration of SYT13-specific small interfering RNA or antibodies significantly inhibited the growth of peritoneal nodules and prolonged survival. SYT13 expression in primary gastric cancer tissues or ascites fluids had diagnostic potential both in the detection and prediction of peritoneal metastasis of gastric cancer. SYT13 may also be a promising target for the treatment of peritoneal metastasis of gastric cancer.

  10. The diagnostic performance and mechanisms of the release into the circulation of novel serum biomarkers for gastric cancer

    Grant number:17K10581  2017.4 - 2020.3

    KANDA Mitsuro

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    Authorship:Coinvestigator(s) 

    Development of high-performance serum biomarkers will likely improve treatment outcomes of patients with gastric cancer (GC). We conducted a prospective multicenter observational study aimed at validating the diagnostic performance of these potential markers. We analyzed serum levels before and after surgery of the three potential biomarkers in patients with GC and healthy volunteers. Quantification of serum and GC tissue levels was performed using an ELISA. Area under the curve values that discriminated patients with GC from healthy controls were-0.7058, 0.6188, and 0.5031 for ANOS1, DPYSL3, and MAGED2, respectively. Serum ANOS1 levels were significantly elevated in patients with stage I GC compared with those of healthy controls and decreased after resection of primary GC lesions. The combination of serum ANOS1 and DPYSL3 levels increased the AUC value that discriminated patients with GC from healthy controls.

  11. 介入による消化器癌周術期高齢者機能の改善と機能低下に影響するバイオマーカー探索

    Grant number:17K01841  2017.4 - 2019.3

    基盤研究(C)

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    Authorship:Principal investigator 

    Grant amount:\4550000 ( Direct Cost: \3500000 、 Indirect Cost:\1050000 )

  12. Novel surgical education system improved by instructional design

    Grant number:16K08868  2016.4 - 2020.3

    Fujiwara Michitaka

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    Authorship:Coinvestigator(s) 

    In this study we create an outcome-based training course for endoscopic surgery.
    Competences required for each operative procedure were analyzed and subdivided, and the unit was defined as “module”. At first the tasks of conventional dry laboratory were applied to these modules, and the new training systems were constructed. Using the method of instructional design, the structure of modules was modified and a module was rebuilt while performing surgical seminars. A course for laparoscopic cholecystectomy that most surgeon initially learn was designed as a model of procedure course. New box trainer related to many modules was developed as a module improvement.

  13. 内視鏡手術シミュレーション訓練の新しい統合的基本タスク

    Grant number:26460594  2014.5 - 2016.3

    基盤研究(C)

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    Authorship:Principal investigator 

    Grant amount:\5070000 ( Direct Cost: \3900000 、 Indirect Cost:\1170000 )

  14. Novel integrated simulation task for laparoscopic surgery training

    Grant number:26460594  2014.4 - 2018.3

    Tanaka Chie

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    Authorship:Principal investigator 

    Grant amount:\5070000 ( Direct Cost: \3900000 、 Indirect Cost:\1170000 )

    Regarding the training of endoscopic surgery, we usually use animal laboratory training as intermediate task between simulation training of basic technique and on-the-job training during actual operation, while there are many problems in the animal laboratory training as well known.
    In this study, we aimed to create new tasks to replace animal trainings. We developed the perivascular dissection program and the intestinal anastomosis program as the integrated tasks combining basic procedures. We created various phantoms of intestinal tract and box trainers. We also used VR module for the perivascular dissection program. Evaluation of both program was based on a checklist of a supervising doctor and a trainee and the results were fed back to the trainee in the briefing. We actually perform these programs in our simulation center, improving the systems.

  15. 手術中の医療者の疲労,ストレスの客観的評価,リアルタイム測定法の研究

    2013.4 - 2015.3

    科学研究費補助金  基盤研究(B)

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    Authorship:Coinvestigator(s) 

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