Faculty Profiles - MUTSUGA Masato

Papers - MUTSUGA Masato

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The number of cardiovascular surgeries in Japan may decrease after 2020

Usui Akihiko, Abe Tomonobu, Araki Yoshimori, Narita Yuji, Mutsuga Masato, Oshima Hideki

NAGOYA JOURNAL OF MEDICAL SCIENCE Vol. 77 ( 3 ) page： 389 - 398 2015.8

Impact of Surgical Stroke on the Early and Late Outcomes After Thoracic Aortic Operations Reviewed

Noritaka Okada, Hideki Oshima, Yuji Narita, Tomonobu Abe, Yoshimori Araki, Masato Mutsuga, Kazuro L. Fujimoto, Yoshiyuki Tokuda, Akihiko Usui

ANNALS OF THORACIC SURGERY Vol. 99 ( 6 ) page： 2017 - 2023 2015.6

Publishing type：Research paper (scientific journal) Publisher：ELSEVIER SCIENCE INC

Background. Thoracic aortic operations still remain associated with substantial risks of death and neurologic injury. This study investigated the impact of surgical stroke on the early and late outcomes, focusing on the physical status and quality of life (QOL).
Methods. From 1986 to 2008, 500 patients (aged 63 +/- 13 years) underwent open thoracic aortic repair for root and ascending (31%), arch (39%), extended arch (10%), and descending and thoracoabdominal (19%) aneurysms. Brain protection consisted of retrograde cerebral perfusion (52%), antegrade cerebral perfusion (29%), and simple deep hypothermic circulatory arrest (19%). Surgical stroke was defined as a neurologic deficit persisting more than 72 hours after the operation. QOL was assessed with the Short-Form 36 Health Survey Questionnaire 5.9 +/- 4.2 years after the operation.
Results. Stroke occurred in 10.3% of patients. Hospital mortality was 21% in the stroke group and 2.7% in the nonstroke group (p < 0.001). At hospital discharge, 76% of survivors in the stroke group had permanent neurologic deficits (PNDs), with sustained tracheostomy in 39%, tube feeding in 46%, and gastrostomy in 14%, and 89% required transfer to other facilities. PND was an independent risk factor for late death (hazard ratio, 2.29; 95% confidence interval, 1.04 to 4.62; p = 0.041) in a multivariate analysis. The physical component of the QOL score was worse in the PND group (51% vs 100%; p = 0.039), whereas the mental component was similar in both groups (14% vs 14%).
Conclusions. Surgical stroke is associated with high hospital mortality and PNDs that decrease late survival and the physical component score of the QOL survey. (C) 2015 by The Society of Thoracic Surgeons

DOI： 10.1016/j.athoracsur.2015.01.033

Web of Science

PubMed

Influence of the characteristics of Japanese patients on the long-term outcomes after aortic valve replacement: results of a microsimulation Reviewed

Tomonobu Abe, Hideki Oshima, Yuji Narita, Yoshimori Araki, Masato Mutsuga, Kazuro Fujimoto, Yoshiyuki Tokuda, Sachie Terazawa, Kei Yagami, Akihiko Usui

General Thoracic and Cardiovascular Surgery Vol. 63 ( 5 ) page： 260 - 266 2015.5

Open stentの適応と問題点広範囲弓部瘤に対するFrozen Elephant Trunk;FET法の適応と問題点

六鹿雅登, 伊藤英樹, 阿部知伸, 大島英輝, 碓氷章彦

日本血管外科学会雑誌 Vol. 24 ( 3 ) page： 302 - 302 2015.5

An L-Shaped Incision for an Extensive Thoracic Aortic Aneurysm and Coronary Artery Bypass Using the Left Internal Thoracic Artery. Reviewed

Abe T, Suenaga H, Oshima H, Araki Y, Mutsuga M, Fujimoto K, Usui A

Aorta (Stamford, Conn.) Vol. 3 ( 2 ) page： 86 - 9 2015.4

心臓血管 B型解離性大動脈瘤の治療戦略

荒木善盛, 碓永章彦, 大島英揮, 阿部知伸, 成田裕司, 六鹿雅登, 藤本和朗, 寺澤幸枝, 八神啓, 伊藤英樹, 藤井恵

日本外科学会定期学術集会抄録集 Vol. 115回 page： OP - 5 2015.4

大動脈弁狭窄ハイリスク症例に対する治療その適応と成績心臓血管ハイリスク高齢者大動脈弁狭窄症に対するTAVRの適応 risk-SCOREと医療費からの検討

大島英揮, 成田裕司, 阿部知伸, 荒木善盛, 藤本和朗, 六鹿雅登, 寺澤幸枝, 八神啓, 伊藤英樹, 碓氷章彦

日本外科学会定期学術集会抄録集 Vol. 115回 page： PD - 1 2015.4

IMPACT OF THE INTRAOPERATIVE USE OF FIBRINOGEN CONCENTRATE FOR HYPOFIBRINOGENEMIA DURING THORACIC AORTIC SURGERY Reviewed

Yoshimori Araki, Akihiko Usui, Hideki Oshima, Tomonobu Abe, Kazuro Fujimoto, Masato Mutsuga, Yoshiyuki Tokuda, Sachie Terazawa, Kei Yagami, Hideki Ito

NAGOYA JOURNAL OF MEDICAL SCIENCE Vol. 77 ( 1-2 ) page： 265 - 273 2015.2

Language：English Publishing type：Research paper (scientific journal) Publisher：NAGOYA UNIV, SCH MED

Thoracic aortic surgery often causes massive bleeding due to coagulopathy. Hypofibrinogenemia is one of the major causative factors, but the utility of the intraoperative administration of fibrinogen concentrate has not yet been proven. The aim of this study was to estimate incidence of hypofibrinogenemia and to evaluate efficacy of using fibrinogen concentrate intraoperatively. The perioperative serum fibrinogen levels (SFL) had routinely been measured in consecutive 216 thoracic aortic surgeries performed from 2010 to 2012. Fibrinogen concentrate was principally used for hypofibrinogenemia (< 150 mg/dl of SFL) at cardiopulmonary bypass (CPB) termination. The patients who received fibrinogen concentrate (FIB group) were compared with the patients who did not received (non Fib group). There were 147 patients (68%) in FIB group at a dose of 5.5 +/- 3.5 g. The SFL were dramatically decreased with values of 164 +/- 71 mg/dl at CPB termination, compared to the preoperative SFL of 352 +/- 131 mg/dl. In the FIB group, the intraoperative and postoperative SFLs were 139 +/- 53 and 262 +/- 75 (mg/dl), respectively. Thus the SFL was recovered quickly by the administration. 110 cases (51%) showed hypofibrinogenemia at the termination of CPB. The predictors of hypofibrinogenemia were preoperative SFL < 250 mg/dl, emergency surgery and thracoabdominal aortic surgery. Hypofibrinogenemia frequently was observed at the termination of CPB during thoracic aortic surgery. Administering intraoperative fibrinogen concentrate appears to be a useful option to treat coagulopathy.

Web of Science

胸部大血管手術におけるフィブリノゲン製剤使用の実際

荒木善盛, 伊藤英樹, 八神啓, 寺澤幸枝, 徳田順之, 六鹿雅登, 藤本和朗, 阿部知伸, 大島英揮, 碓氷章彦

日本心臓血管外科学会雑誌 Vol. 44 ( Suppl. ) page： 342 - 342 2015.1

当院における胸部人工血管感染に対する再血行再建術の術後成績

大野司, 大島英揮, 成田裕司, 阿部知伸, 荒木善盛, 六鹿雅登, 藤本和朗, 徳田順之, 寺澤幸枝, 八神啓, 伊藤英樹, 蒔苗永, 藤井恵, 末永啓人, 碓氷章彦

日本心臓血管外科学会雑誌 Vol. 44 ( Suppl. ) page： 497 - 497 2015.1

心臓移植実施施設の必要性の検討拡大か縮小か?地域の重症心不全治療からの考察

藤本和朗, 碓氷章彦, 大島英輝, 成田裕司, 阿部知伸, 荒木善盛, 六鹿雅登, 徳田順之, 寺澤幸枝

日本心臓血管外科学会雑誌 Vol. 44 ( Suppl. ) page： 508 - 508 2015.1

胸部大動脈再手術症例の現況とその手術戦略

六鹿雅登, 伊藤英樹, 八神啓, 寺澤幸枝, 徳田順行, 藤本和朗, 荒木善盛, 阿部知伸, 成田裕司, 大島英輝, 碓氷章彦

日本心臓血管外科学会雑誌 Vol. 44 ( Suppl. ) page： 436 - 436 2015.1

大動脈弁治療の現在と未来術式と人工弁の選択本邦の大動脈置換術後の弁関連合併症の特徴と、それが人工弁選択に与える影響

阿部知伸, 大島英揮, 成田裕司, 荒木善盛, 六鹿雅登, 藤本和郎, 徳田順之, 寺澤幸枝, 八神啓, 伊藤英樹, 碓氷章彦

日本心臓血管外科学会雑誌 Vol. 44 ( Suppl. ) page： 149 - 149 2015.1

TEVAR後ステントグラフト抜去を伴う開胸大動脈手術を要した症例の検討

寺澤幸枝, 大島英揮, 末永啓人, 大野司, 藤井恵, 蒔苗永, 伊藤英樹, 八神啓, 徳田順之, 藤本和朗, 六鹿雅登, 荒木善盛, 成田裕司, 阿部知伸, 碓氷章彦

日本心臓血管外科学会雑誌 Vol. 44 ( Suppl. ) page： 324 - 324 2015.1

ガイドライン施行後の冠血行再建術 2011年ガイドライン施行後にみられる外科的冠血行再建術における変化

大島英揮, 成田裕司, 阿部知伸, 荒木善盛, 六鹿雅登, 藤本和朗, 徳田順之, 碓氷章彦

日本心臓血管外科学会雑誌 Vol. 44 ( Suppl. ) page： 173 - 173 2015.1

三尖弁輪形成術遠隔期にmoderate以上の逆流が残存する危険因子の検討

伊藤英樹, 大島英揮, 成田裕司, 阿部知伸, 荒木善盛, 六鹿雅登, 藤本和朗, 徳田順之, 寺澤幸枝, 八神啓, 蒔苗永, 藤井恵, 大野司, 末永啓人

日本心臓血管外科学会雑誌 Vol. 44 ( Suppl. ) page： 234 - 234 2015.1

冠動脈疾患を合併する胸部大動脈手術症例の検討

伊藤英樹, 大島英揮, 成田裕司, 阿部知伸, 荒木善盛, 六鹿雅登, 藤本和朗, 徳田順之, 寺澤幸枝, 八神啓, 蒔苗永, 藤井恵, 大野司, 末永啓人

日本心臓血管外科学会雑誌 Vol. 44 ( Suppl. ) page： 437 - 437 2015.1

多発瘤形成を伴うCervical Aortic Archに対する外科的治療例

伊藤英樹, 大島英揮, 成田裕司, 阿部知伸, 荒木善盛, 六鹿雅登, 藤本和朗, 徳田順之, 寺澤幸枝, 八神啓, 蒔苗永, 藤井恵, 大野司, 末永啓人

日本心臓血管外科学会雑誌 Vol. 44 ( Suppl. ) page： 497 - 497 2015.1

Entire shaggy aortaの治療方針

八神啓, 碓氷章彦, 大島英揮, 成田裕司, 阿部知伸, 荒木善盛, 藤本和朗, 六鹿雅登, 徳田順之, 寺澤幸枝, 蒔苗永, 伊藤英樹, 大野司, 末永啓人

日本心臓血管外科学会雑誌 Vol. 44 ( Suppl. ) page： 322 - 322 2015.1

Debranching TEVARの合併症対策と手技上の工夫

徳田順之, 末永啓人, 藤井恵, 伊藤英樹, 八神啓, 寺澤幸枝, 藤本和朗, 六鹿雅登, 荒木善盛, 成田裕司, 阿部知伸, 大島英揮, 山本清人, 古森公浩, 碓氷章彦

日本心臓血管外科学会雑誌 Vol. 44 ( Suppl. ) page： 326 - 326 2015.1

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Papers - MUTSUGA Masato