2021/03/31 更新

写真a

オオシマ ケンジ
大島 健司
OSHIMA Kenzi
所属
大学院生命農学研究科 応用生命科学専攻 応用生命科学 助教
大学院担当
大学院生命農学研究科
学部担当
農学部
職名
助教
連絡先
メールアドレス

学位 1

  1. 博士(農学) ( 2002年3月   名古屋大学 ) 

研究キーワード 1

  1. ミルク, 上皮細胞, 分泌性小胞, 免疫, 腸内細菌

経歴 3

  1. 名古屋大学大学院   生命農学研究科   助教

    2011年3月 - 現在

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    国名:日本国

  2. the University of Chicago   Department of Molecular Genetics and Cell Biology   Research Associate

    2007年7月 - 2011年2月

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    国名:アメリカ合衆国

  3. 理化学研究所発生再生総合研究センター   研究員

    2002年4月 - 2007年6月

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    国名:日本国

学歴 1

  1. 名古屋大学   農学研究科   応用分子生命科学

    1999年4月 - 2002年3月

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    国名: 日本国

所属学協会 4

  1. 日本分子生物学会

  2. 日本農芸化学会

  3. 日本栄養・食糧学会

  4. 日本細胞生物学会

 

論文 33

  1. Hyaluronan degradation and release of a hyaluronan-aggrecan complex from perineuronal nets in the aged mouse brain

    Sugitani Kei, Egorova Diana, Mizumoto Shuji, Nishio Shunsuke, Yamada Shuhei, Kitagawa Hiroshi, Oshima Kenzi, Nadano Daita, Matsuda Tsukasa, Miyata Shinji

    BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS   1865 巻 ( 2 ) 頁: 129804   2021年2月

  2. A pericellular hyaluronan matrix is required for the morphological maturation of cortical neurons

    Takechi Mina, Oshima Kenzi, Nadano Daita, Kitagawa Hiroshi, Matsuda Tsukasa, Miyata Shinji

    BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS   1864 巻 ( 10 ) 頁: 129679   2020年10月

  3. Transcription Factor Sox4 as a Potential Player in Mammary Gland Involution

    Shibayama Hirohisa, Yamamoto Tomomi, Oshima Kenzi, Matsuda Tsukasa, Nadano Daita

    DNA AND CELL BIOLOGY   38 巻 ( 10 ) 頁: 1125-1133   2019年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1089/dna.2019.4700

    Web of Science

    PubMed

  4. 腸上皮 Caco-2 細胞単層培養の頂端側におけるラクトフェリンの取り込みとビフィズス菌増殖促進ペプチドを含む分解断片の放出( 招待有り

    秋山友香、西尾俊亮、大島健司、織田浩嗣、山内恒治、阿部文明、松田幹

    ラクトフェリン 2019     2019年5月

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    記述言語:日本語   掲載種別:研究論文(研究会,シンポジウム資料等)  

  5. 乳に含まれる細胞外小胞と酸性リン脂質結合タンパク質の新たな機能:局在変化が細胞外小胞の機能を規定する

    大島 健司

    化学と生物   57 巻 ( 4 ) 頁: 205 - 206   2019年

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    出版者・発行元:公益社団法人 日本農芸化学会  

    DOI: 10.1271/kagakutoseibutsu.57.205

  6. The mRNA-binding protein Serbp1 as an auxiliary protein associated with mammalian cytoplasmic ribosomes

    Muto Akiko, Sugihara Yoshihiko, Shibakawa Minami, Oshima Kenzi, Matsuda Tsukasa, Nadano Daita

    CELL BIOCHEMISTRY AND FUNCTION   36 巻 ( 6 ) 頁: 312-322   2018年8月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1002/cbf.3350

    Web of Science

    PubMed

  7. Apical-to-basolateral transepithelial transport of cow's milk caseins by intestinal Caco-2 cell monolayers: MS-based quantitation of cellularly degraded alpha- and beta-casein fragments 査読有り

    Sakurai Nao, Nishio Shunsuke, Akiyama Yuka, Miyata Shinji, Oshima Kenzi, Nadano Daita, Matsuda Tsukasa

    JOURNAL OF BIOCHEMISTRY   164 巻 ( 2 ) 頁: 113-125   2018年8月

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    担当区分:筆頭著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1093/jb/mvy034

    Web of Science

    PubMed

  8. 密度勾配遠心分離とSDSゲル電気泳動を用いた分泌膜小胞結合タンパク質の解析 査読有り

    中谷 肇, 安枝 武彦, 大島 健司, 松田 幹

    電気泳動   61 巻 ( 2 ) 頁: 115 - 119   2017年11月

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    記述言語:日本語   出版者・発行元:日本電気泳動学会  

    <p>密度勾配超遠心分離とSDS-PAGEを用いて,マウス乳中に含まれる分泌膜小胞結合タンパク質,MFG-E8,の研究を行った.搾乳した新鮮なマウス乳に含まれる分泌膜小胞である乳脂肪球とエキソソームは密度勾配超遠心分離により,それぞれ低密度画分と高密度画分に分画され,SDS-PAGE免疫ブロット解析によりMFG-E8は主に乳脂肪球画分に検出された.このようなMFG-E8の分布は強制離乳により変化し,エキソソーム画分や可溶性タンパク質画分を含む幅広い密度範囲に分布した.乳脂肪球の蛍光免疫染色の結果などから,MFG-E8は分泌後間もない新鮮な乳脂肪球の表面には少なく時間経過とともに増加することが示された.MFG-E8の結合により乳脂肪球は貪食され易くなったことから,アポトーシス細胞と同様に,MFG-E8は古くなった乳脂肪球においてもeat-me signalとして機能することが示唆された.</p>

    DOI: 10.2198/electroph.61.115

  9. Extracellular vesicle-mediated MFG-E8 localization in the extracellular matrix is required for its integrin-dependent function in mouse mammary epithelial cells 査読有り

    Ooishi Takuya, Nadano Daita, Matsuda Tsukasa, Oshima Kenzi

    GENES TO CELLS   22 巻 ( 10 ) 頁: 885 - 899   2017年10月

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    担当区分:最終著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1111/gtc.12521

    Web of Science

    PubMed

  10. Evaluation of allergenic potential for rice seed protein components utilizing a rice proteome database and an allergen database in combination with IgE-binding of recombinant proteins 査読有り

    Kana Hirano, Shingo Hino, Kenzi Oshima, Daita Nadano, Atsuo Urisu, Fumio Takaiwa & Tsukasa Matsuda.

    Biosci Biotechnol Biochem.   80 巻 ( 3 ) 頁: 564-73   2016年1月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1080/09168451.2015.1116927

  11. A protective effect of milk fat globule EGF factor VIII (MFG-E8) on the spontaneous fusion of milk fat globules in breast milk. 査読有り

    Takehiko Yasueda, Kenzi Oshima, Hajime Nakatani, Kanji Tabuchi, Daita Nadano and Tsukasa Matsuda.

    Journal of Biochemistry   158 巻 ( 1 ) 頁: 25 - 35   2015年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1074/jbc.M114.598821

  12. A Transport and Retention Mechanism for the Sustained Distal Localization of Spn-F-IKKε During Drosophila Bristle Elongation. 査読有り 国際共著

    Tetsuhisa Otani, Kenzi Oshima, Akiyo Kimpara, Michiko Takeda, Uri Abdu, Shigeo Hayashi

    Development   142 巻 ( 13 ) 頁: 2338 - 2351   2015年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1242/dev.121863

  13. Glycosylated Chicken ZP2 Accumulates in the Egg Coat of Immature Oocytes and Remains Localized to the Germinal Disc Region of Mature Eggs. 査読有り

    Shunsuke Nishio, Yoshinori Kohno, Yuki Iwata, Mayumi Arai, Hiroki Okumura, Kenzi Oshima, Daita Nadano, and Tsukasa Matsuda.

    Biol Reprod.   91 巻 ( 5 ) 頁: 107   2014年11月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  14. Lyar, a cell growth-regulating zinc finger protein, was identified to be associated with cytoplasmic ribosomes in male germ and cancer cells. 査読有り

    Kahori Yonezawa, Yoshihiko Sugihara, Kenzi Oshima, Tsukasa Matsuda, Daita Nadano.

    Mol Cell Biochem.   395 巻 ( 1 ) 頁: 221-229   2014年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1007/s11010-014-2128-x

  15. Macroglobulin complement-related encodes a protein required for septate junction organization and paracellular barrier function in Drosophila. 査読有り

    Sonia Hall, Courtney Bone, Kenzi Oshima, Liang Zhang, Molly McGraw, Bethany Lucas, Richard G. Fehon and Robert E. Ward IV.

    Development   141 巻 ( 4 ) 頁: 889-898   2014年2月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  16. A lactoferrin-receptor, intelectin 1, affects uptake, sub-cellular localization and release of immunochemically detectable lactoferrin by intestinal epithelial Caco-2 cells. 査読有り

    Akiyama Y, Oshima K, Kuhara T, Shin K, Abe F, Iwatsuki K, Nadano D, Matsuda T.

    The Journal of Biochemistry.   154 巻 ( 5 ) 頁: 437-448.   2013年11月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  17. ラクトフェリン受容体を高発現するヒト腸上皮様Caco-2細胞における牛乳ラクトフェリンの取り込みと断片化および放出

    秋山友香、大島健司、久原徹哉、新 光一郎、灘野大太、 阿部文明、松田 幹

    ラクトフェリン2013     頁: 1-6   2013年10月

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    記述言語:日本語   掲載種別:研究論文(大学,研究機関等紀要)  

  18. Allergenic potential of rice-pollen proteins: expression, immuno-cross reactivity and IgE-binding. 査読有り

    Hirano K, Hino S, Oshima K, Okajima T, Nadano D, Urisu A, Takaiwa F, Matsuda T

    The Journal of Biochemistry.   154 巻 ( 2 ) 頁: 195-205   2013年8月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  19. Identification and expression of an autosomal paralogue of ribosomal protein S4, X-linked, in mice: Potential involvement of testis-specific ribosomal proteins in translation and spermatogenesis. 査読有り

    Sugihara Y, Sadohara E, Yonezawa K, Kugo M, Oshima K, Matsuda T, Nadano D.

    Gene   521 巻 ( 1 ) 頁: 91-99   2013年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  20. Intracellular Retention and Subsequent Release of Bovine Milk Lactoferrin Taken Up by Human Enterocyte-Like Cell Lines, Caco-2, C2BBe1 and HT-29. 査読有り

    Yuka AKIYAMA, Kenzi OSHIMA, Kouichirou SHIN, Hiroyuki WAKABAYASHI, Fumiaki ABE, Daita NADANO, Tsukasa MATSUDA

    Bioscience, Biotechnology, and Biochemistry   77 巻 ( 5 ) 頁: 1023 - 1029   2013年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: https://doi.org/10.1271/bbb.121011

  21. Dephosphorylation reduces passage of ovalbumin antigen through intestinal epithelial Caco-2 cell monolayers. 査読有り

    Matsubara T, Akiyama Y, Oshima K, Okajima T, Nadano D, Matsuda T.

    The Journal of Biochemistry.   153 巻 ( 4 ) 頁: 347-354   2013年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1093/jb/mvs154

  22. Post-weaning increases in the milk-fat globule EGF-factor VIII (MFG-E8) on fat globules in mouse milk and in the uptake of the fat globules by HC11 mammary epithelial cells. 査読有り 国際共著

    Hajime Nakatani, Takehiko Yasueda, Kenzi Oshima, Tetsuya Okajima, Daita Nadano, David J Flint, and Tsukasa Matsuda.

    Journal of biochemistry     2013年1月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Milk fat globules (MFGs) secreted by lactating mammary gland are unique lipid surrounded by a phospholipid bi-layer. We report here post-weaning changes in milk fat globule EGF factor VIII (MFG-E8) and annexin V-accessible phosphatidylserine on the surface of MFGs. The MFG content in milk markedly decreased to about half within 2 days after forced weaning, despite a slight increase in milk protein content. Immunofluorescence-staining of MFGs using anti-MFG-E8 and annexin V indicated that MFG-E8 was present on some, but not all, MFGs before weaning, whereas most of MFGs were MFG-E8-positive and annexin V-negative after weaning. Free MFG-E8 with binding activity to phosphatidylserine was present abundantly in the post-weaning milk, and indeed exhibited binding to MFGs in pre-weaning milk. MFGs were taken up by HC11 mouse mammary epithelial cells in vitro, and those from post-weaning milk were remarkable for such cellular uptake. Moreover, the uptake of MFGs by the cells was inhibited by an anti-MFG-E8 antibody. Taken together, these findings suggest that MFG-E8 plays a critical role in regulation of MFG dynamics after weaning or during the suckling interval through the control of MFG-epithelial cell interaction in lactating mammary glands.

    DOI: 10.1093/jb/mvs116

  23. Re-Evaluation of Milk-Fat Globule EGF-Factor VIII (MFG-E8) as an Intrinsic Component of the Mouse Milk-Fat Globule Membrane. 査読有り

    Nakatani, Hajime and Yasueda, Takehiko and Oshima, Kenzi and Nadano, Daita and Matsuda, Tsukasa

    Bioscience, biotechnology, and biochemistry     2012年11月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    In lactating mammary glands, milk fat is secreted as fat globules surrounded by a cell plasma membrane containing characteristic membrane-associated proteins. Among these, butyrophilin has been shown to be specific and intrinsic to the fat globule membrane, whereas milk-fat globule EGF-factor VIII (MFG-E8) is uncertain. We characterized in the present study MFG-E8 in milk fat globules and in the culture medium of HC11 mammary epithelial cells. MFG-E8 was immunologically detected in the mammary tissues of both pregnant and lactating mice. Double-immunofluorescence staining for MFG-E8 and butyrophilin showed diversity in the MFG-E8-staining intensity among different fat globules in milk. HC11 cells secreted monomeric MFG-E8 with phosphatidylserine-binding activity, despite no fat globules being detected in the cells. This secretion was upregulated by not only prolactin but also by insulin or EGF. These results suggest that milk MFG-E8 was not equally present among fat globules and not necessarily intrinsic to the fat globules.

    DOI: 10.1271/bbb.120412

  24. The murine Gcap14 gene encodes a novel microtubule binding and bundling protein. 査読有り

    Hosono, Hitomi and Yamaguchi, Nao and Oshima, Kenzi and Matsuda, Tsukasa and Nadano, Daita

    FEBS letters   586 巻 ( 10 ) 頁: 1426--1430   2012年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Microtubules form flexible fibers, which are utilized in cell proliferation and differentiation. Although the flexibility of microtubules was shown to be regulated by various microtubule-associated proteins, this regulation is still far from complete understanding. Here, we report a new potential regulator of microtubules in mammals. Gcap14 colocalizes with microtubules in mammalian cells transfected with Gcap14 expression vector. Association of Gcap14 with microtubules was confirmed by biochemical subcellular fractionation. Recombinant Gcap14 protein cosedimented with pure microtubules, indicating a direct binding between the two. Furthermore, recombinant Gcap14 was shown to have the ability of inducing microtubule bundling in vitro.

    DOI: 10.1016/j.febslet.2012.04.008

  25. Discharge of solubilized and Dectin-1-reactive [beta]-glucan from macrophage cells phagocytizing insoluble [beta]-glucan particles: involvement of reactive oxygen species (ROS)-driven degradation. 査読有り

    Shingo Hino; Aki Kito; Remi Yokoshima; Ryosuke Sugino; Kenzi Oshima; Tatsuya Morita; Tetsuya Okajima; Daita Nadano; Koji Uchida;Tsukasa Matsuda.

    Biochem Biophys Res Commun   421 巻 ( 2 ) 頁: 329–334   2012年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    ... These results suggest that degraded but Dectin - 1 - reactive β- glucan is discharged from macrophage cells ... ROS -production inhibitors reduced soluble β- glucan discharge from the ... Soluble β- glucan produced by in vitro ROS - driven degradation activated macrophages . ...

    DOI: 10.1016/j.bbrc.2012.04.009

  26. Analysis of protein dynamics within the septate junction reveals a highly stable core protein complex that does not include the basolateral polarity protein Discs large 査読有り

    K Oshima, R G Fehon

    J. Cell Sci.   124 巻 ( 16 ) 頁: 2861-2871   2011年8月

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    担当区分:筆頭著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1242/jcs.087700

  27. IKKε regulates cell elongation through recycling endosome shuttling. 査読有り

    Otani, T, Oshima, K, Onishi, S, Takeda, M, Shinmyozu, K, Yonemura, S, Hayashi, S.

    Dev Cell   20 巻 ( 2 ) 頁: 219-232   2011年2月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.devcel.2011.02.001

  28. Crooked, Coiled and Crimpled are three Ly6-like proteins required for proper localization of septate junction components 査読有り

    Nilton, A, Oshima, K, Zare, F, Byri, S, Nannmark, U, Nyberg, K G, Fehon, R G, and Uv, A E

    Development   137 巻 ( 14 ) 頁: 2427-2437   2010年6月

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    担当区分:筆頭著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1242/dev.052605

  29. IKKε regulates F-actin assembly and interacts with Drosophila IAP1 in cellular morphogenesis 査読有り

    Oshima, K, Takeda, M, Kuranaga, E, Ueda, R, Aigaki, T, Miura, M, and Hayashi, S.

    Current Biology   16 巻 ( 15 ) 頁: 1531-1537   2006年8月

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    担当区分:筆頭著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.cub.2006.06.032

  30. Weaning-induced expression of a milk-fat globule protein, MFG-E8, in mouse mammary glands, as demonstrated by the analyses of its mRNA, protein and phosphatidylserine-binding activity 査読有り

    Nakatani, H, Aoki, N, Nakagawa, Y, Jin-No, S, Aoyama, K, Oshima, K, Ohira, S, Sato, C, Nadano, D, Matsuda, T.

    Biochem J.   395 巻   頁: 21-30   2006年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1042/BJ20051459

  31. Secretion of a peripheral membrane protein, MFG-E8, as a complex with membrane vesicles. 査読有り

    Oshima, Kenji and Aoki, Naohito and Kato, Takeo and Kitajima, Ken and Matsuda, Tsukasa

    European journal of biochemistry / FEBS   269 巻 ( 4 ) 頁: 1209--1218   2002年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    MFG-E8 (milk fat globule-EGF factor 8) is a peripheral membrane glycoprotein, which is expressed abundantly in lactating mammary glands and is secreted in association with fat globules. This protein consists of two-repeated EGF-like domains, a mucin-like domain and two-repeated discoidin-like domains (C-domains), and contains an integrin-binding motif (RGD sequence) in the EGF-like domain. To clarify the role of each domain on the peripheral association with the cell membrane, several domain-deletion mutants of MFG-E8 were expressed in COS-7 cells. The immunofluorescent staining of intracellular and cell-surface proteins and biochemical analyses of cell-surface-biotinylated and secreted proteins demonstrated that both of the two C-domains were required for the membrane association. During the course of these studies for domain functions, MFG-E8, but not C-domain deletion mutants, was shown to be secreted as membrane vesicle complexes. By size-exclusion chromatography and ultracentrifugation analyses, the complexes were characterized to have a high-molecular mass, low density and higher sedimentation velocity and to be detergent-sensitive. Not only such a exogenously expressed MFG-E8 but also that endogenously expressed in a mammary epithelial cell line, COMMA-1D, was secreted as the membrane vesicle-like complex. Scanning electron microscopic analyses revealed that MFG-E8 was secreted into the culture medium in association with small membrane vesicles with a size from 100 to 200 nm in diameter. Furthermore, the expression of MFG-E8 increased the number of these membrane vesicle secreted into the culture medium. These results suggest a possible role of MFG-E8 in the membrane vesicle secretion, such as budding or shedding of plasma membrane (microvesicles) and exocytosis of endocytic multivesicular bodies (exosomes).

  32. An ELISA-Based Assay for Detergent-solubilized Cellular .BETA.1,4-Galactosyltransferase Activity. Use of a Polyacrylamide Derivative with GlcNAc-.BETA. Side Chains as a Solid Phase Acceptor Substrate. 査読有り

    OUBIHI, Mohamed and Oshima, Kenji and Aoki, Naohito and KOBAYASHI, Kazukiyo and Kitajima, Ken and Matsuda, Tsukasa

    Bioscience, biotechnology, and biochemistry   64 巻 ( 4 ) 頁: 785--792   2000年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    ... Biochem., 64 (4), 785-792, 2000 M An ELISA - Based Assay for Detergent - solubilized Cellular {\ss

    DOI: 10.1271/bbb.64.785

  33. Lactation-dependent expression of an mRNA splice variant with an exon for a multiply O-glycosylated domain of mouse milk fat globule glycoprotein MFG-E8. 査読有り

    Oshima, K and Aoki, N and Negi, M and Kishi, M and Kitajima, K and Matsuda, T

    Biochemical and biophysical research communications   254 巻 ( 3 ) 頁: 522--528   1999年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Expression of mRNA encoding MFG-E8, a milk fat-associated glycoprotein was investigated in mouse mammary gland. Two forms of mRNA, long and short variants, were shown to be expressed in the mammary tissue by RT-PCR analysis. Sequence analyses of these two variants and an isolated MFG-E8 gene segment indicated that the long and short mRNA variants resulted from an alternative splicing of a single pre-mRNA through in-flame inclusion and skipping of one exon, which encodes a proline/threonine (Pro/Thr)-rich domain. The long variant was expressed predominantly in mammary gland and the expression level was remarkably increased at late gestation and kept high during lactation. On the contrary, the short variant was detected ubiquitously in various tissues and its expression in the mammary gland was rather decreased in a lactation dependent manner. Expression of the long variant was also detected in a mouse mammary epithelial cell line, COMMA-1D, and enhanced by incubation with lactogenic hormones. Glycosylation inhibition analyses using tunicamycin and alpha-benzyl-GalNAc were conducted with COS7 cells transfected with plasmids expressing each mRNA variant, demonstrating that a fully glycosylated product of the long mRNA variant was not only N-glycosylated but also multiply O-glycosylated, whereas a product of the short one had only N-glycan(s). These results suggest that the alternative splicing plays a critical role for the mammary-specific and lactation-dependent expression of the MFG-E8 isoform and that the multiply O-glycosylated Pro/Thr-rich domain of this isoform is functionally important for formation of milk fat globules in mammary epithelial cells.

    DOI: 10.1006/bbrc.1998.0107

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書籍等出版物 1

  1. MFG-E8: Origin, Structure, Expression, Functions and Regulation

    Kenzi Oshima, Takehiko Yasueda, Shunsuke Nishio and Tsukasa Matsuda( 担当: 共著)

    Springer Netherlands  2014年3月  ( ISBN:978-94-017-8765-9

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    記述言語:英語

講演・口頭発表等 3

  1. 離乳期マウスにおける腸内細菌叢形成に影響する消化管内タンパク質の発現解析

    鬼頭 一平、伊藤 大貴、宮田 真路、灘野 大太、松田 幹、大島 健司

    日本農芸化学会2020年度大会  日本農芸化学会

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    開催年月日: 2020年3月

    記述言語:日本語  

  2. 腸上皮Caco-2細胞単層培養の頂端側におけるラクトフェリンの取り込みとビフィズス菌増殖促進ペプチドを含む分解断片の放出

    大島 健司、秋山 友香、西尾 俊亮、織田 浩嗣、山内 恒治、阿部 文明、松田 幹

    日本ラクトフェリン学会第8回学術集会  2018年10月  日本ラクトフェリン学会

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    開催年月日: 2018年10月

    記述言語:日本語   会議種別:口頭発表(一般)  

    開催地:広島大学広仁会館  

  3. 乳児腸管におけるラクトフェリンの分解吸収機構の解析

    石川千尋,宮田真路,灘野大太,松田幹,大島健司

    日本農芸化学会中部支部第183回支部例会  日本農芸化学会中部支部

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    開催年月日: 2018年9月

    記述言語:日本語   会議種別:ポスター発表  

    開催地:名古屋大学豊田講堂  

 

担当経験のある科目 (本学) 16

  1. 食品衛生学

    2020

  2. 生命農学演習1

    2020

  3. 情報リテラシー入門

    2020

  4. 食品衛生学

    2019

  5. 応用生命科学実験実習1

    2019

  6. 分子細胞生物学特論2

    2019

  7. 応用生命科学実験実習1

    2018

  8. 分子細胞生物学特論2

    2018

  9. 応用生命化学特論II

    2017

  10. 応用生命科学実験実習1

    2017

  11. 応用生命科学実験実習1

    2016

  12. 応用生命化学特論II

    2016

  13. 応用生命化学特論II

    2015

  14. 応用生命科学実験実習1

    2015

  15. 応用生命科学実験実習1

    2014

  16. 応用生命化学特論IV

    2014

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担当経験のある科目 (本学以外) 2

  1. 食品学実験I

    2020年9月 - 2021年3月 名古屋文理大学)

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    科目区分:学部専門科目 

  2. 化学の世界

    2020年4月 - 2020年7月 椙山女学園大学)

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    科目区分:学部教養科目 

 

学術貢献活動 1

  1. 日本栄養・食糧学会中部支部 会計幹事

    役割:企画立案・運営等

    日本栄養・食糧学会  2020年4月 - 現在

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    種別:学会・研究会等