論文 - 嘉村 巧
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*Fbxw8 is essential for Cul1-Cul7 complex formation and for placental development. 査読有り
Tsunematsu, R., Nishiyama, M., Kotoshiba, S., Saiga, T., Kamura, T., Nakayama, KI.
Molecular and Cellular Biology 26 巻 ( 16 ) 頁: 6157-6169 2006年8月
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Fbxw7 contributes to tumor suppression by targeting multiple proteins for ubiquitin-dependent degradation. 査読有り
Fujii, Y., Yada, M., Nishiyama, M., Kamura, T., Takahashi, H., Tsunematsu, R., Susaki, E., Nakagawa, T., Matsumoto, A., Nakayama, KI.
Cancer Science 97 巻 ( 8 ) 頁: 729-736 2006年8月
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Role of the UBL-UBA protein KPC2 in degradation of p27 at G1 phase of the cell cycle. 査読有り
Hara, T., Kamura, T., Kotoshiba, S., Takahashi, H., Fujiwara, K., Onoyama, I., Shirakawa, M., Mizushima, N., Nakayama, KI.
Molecular and Cellular Biology 25 巻 ( 21 ) 頁: 9292-9303 2005年11月
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Molecular dissection of the interaction between p27 and KPC, the ubiquitin ligase that regulates proteolysis of p27 in G1 phase. 査読有り
Kotoshiba, S., Kamura, T., Hara, T., Ishida, N., Nakayama, KI.
Journal of Biological Chemistry 280 巻 ( 18 ) 頁: 17694-17700 2005年5月
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Functional regulation of FEZ1 by the U-box-type ubiquitin ligase E4B contributes to neuritogenesis. 査読有り
Okumura, F., Hatakeyama, S., Matsumoto, M., Kamura, T., Nakayama, K.I.
Journal of Biological Chemistry 279 巻 ( 51 ) 頁: 53533-53543 2004年12月
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Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27Kip1 at G1 phase. 査読有り
Kamura, T., Hara, T., Matsumoto, M., Ishida, N., Okumura, F., Hatakeyama, S., Yoshida, M., Nakayama, K., Nakayama, K.I.
Nature Cell Biology 6 巻 ( 12 ) 頁: 1229-1235 2004年12月
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VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases. 査読有り
Kamura, T., Maenaka, K., Kotoshiba, S., Matsumoto, M., Kohda, D., Conaway, R.C., Conaway, J.W., Nakayama, K.I.
Genes & Development 18 巻 ( 24 ) 頁: 3055-3065 2004年12月
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Evidence for impaired Skp2-dependent degradation of p27 in terminal differentiation. 査読有り
Tamamori-Adachi, M., Hayashida, K., Nobori, K., Omizu, C., Yamada, K., Sakamoto, N., Kamura, T., Fukuda, K., Ogawa, S., Nakayama, K.I., Kitajima, S.
Journal of Biological Chemistry 279 巻 ( 48 ) 頁: 50429-50436 2004年11月
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Identification of elongin C and Skp1 sequences that determine cullin selection. 査読有り
Yan, Q., Kamura, T., Cai, Y., Jin, J., Ivan, M., Mushegian, A., Conaway, R.C., Conaway ,J.W.
Journal of Biological Chemistry 279 巻 ( 41 ) 頁: 43019-43026 2004年10月
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U-box protein carboxyl terminus of Hsc70-interacting protein (CHIP) mediates poly-ubiquitylation preferentially on four-repeat Tau and is involved in neurodegeneration of tauopathy. 査読有り
91 巻 ( 2 ) 頁: 299-307 2004年10月
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Phosphorylation- dependent degradation of c-Myc is mediated by the F-box protein Fbw7. 査読有り
Yada, M., Hatakeyama, S., Kamura, T., Nishiyama, M., Tsunematsu, R., Imaki, H., Ishida, N., Okumura, F., Nakayama, K., Nakayama, K.I.
EMBO Journal 23 巻 ( 10 ) 頁: 2116-2125 2004年5月