Updated on 2021/05/25

写真a

 
HASHIMOTO, Hisashi
 
Organization
Nagoya University Graduate School of Science Division of Biological Science Assistant Professor
Title
Assistant Professor

Degree 1

  1. 博士(農学) ( 1998.3   京都大学 ) 

Research Interests 3

  1. 色素細胞

  2. 細胞多様性・新奇細胞種

  3. 細胞進化

Research Areas 3

  1. Others / Others  / Developmental Biology

  2. Others / Others  / Evolutionary Biology

  3. Life Science / Genetics  / Genetics

Current Research Project and SDGs 2

  1. 魚類の多様な色素細胞を作る発生メカニズムの解明

  2. 新奇細胞種の創出を支える進化遺伝基盤の解明

Education 1

  1. Kyoto University   Graduate School, Division of Agriculture

    1994.4 - 1998.3

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    Country: Japan

Professional Memberships 3

  1. 日本発生生物学会

  2. 日本分子生物学会

  3. 日本動物学会

 

Papers 69

  1. Thrombin-deficient mutant of medaka, a model fish, displays serious retardation in blood coagulation

    Watanabe Yuko, Oguri Rina, Suzuki Risa, Meng Qi, Ishikawa Yuta, Tatsukawa Hideki, Hashimoto Hisashi, Hitomi Kiyotaka

    BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY   Vol. 85 ( 4 ) page: 824 - 833   2021.3

  2. Gene disruption of medaka (Oryzias latipes) orthologue for mammalian tissue-type transglutaminase (TG2) causes movement retardation Reviewed

    Watanabe Yuko, Okuya Kazuho, Takada Yuki, Kinoshita Masato, Yokoi Saori, Chisada Shinichi, Kamei Yasuhiro, Tatsukawa Hideki, Yamamoto Naoyuki, Abe Hideki, Hashimoto Hisashi, Hitomi Kiyotaka

    JOURNAL OF BIOCHEMISTRY   Vol. 168 ( 3 ) page: 213 - 222   2020.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1093/jb/mvaa038

    Web of Science

  3. Osteocrin, a peptide secreted from the heart and other tissues, contributes to cranial osteogenesis and chondrogenesis in zebrafish

    Chiba Ayano, Watanabe-Takano Haruko, Terai Kenta, Fukui Hajime, Miyazaki Takahiro, Uemura Mami, Hashimoto Hisashi, Hibi Masahiko, Fukuhara Shigetomo, Mochizuki Naoki

    DEVELOPMENT   Vol. 144 ( 2 ) page: 334 - 344   2017.1

  4. Identification and Characterization of Highly Fluorescent Pigment Cells in Embryos of the Arabian Killifish (Aphanius Dispar) Reviewed International coauthorship

    Hamied Atyaf, Alnedawy Qusay, Correia Ana, Hacker Christian, Ramsdale Mark, Hashimoto Hisashi, Kudoh Tetsuhiro

    ISCIENCE   Vol. 23 ( 11 )   2020.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.isci.2020.101674

    Web of Science

  5. Distinct interactions of Sox5 and Sox10 in fate specification of pigment cells in medaka and zebrafish Reviewed International coauthorship

    Nagao Yusuke, Takada Hiroyuki, Miyadai Motohiro, Adachi Tomoko, Seki Ryoko, Kamei Yasuhiro, Hara Ikuyo, Taniguchi Yoshihito, Naruse Kiyoshi, Hibi Masahiko, Kelsh Robert N., Hashimoto Hisashi

    PLOS GENETICS   Vol. 14 ( 4 )   2018.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1371/journal.pgen.1007260

    Web of Science

  6. Highly efficient generation of knock-in transgenic medaka by CRISPR/Cas9-mediated genome engineering Reviewed

    Watakabe Ikuko, Hashimoto Hisashi, Kimura Yukiko, Yokoi Saori, Naruse Kiyoshi, Higashijima Shin-ichi

    ZOOLOGICAL LETTERS   Vol. 4   2018.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1186/s40851-017-0086-3

    Web of Science

  7. Sox5 is involved in germ-cell regulation and sex determination in medaka following co-option of nested transposable elements. Reviewed International coauthorship

    Schartl M, Schories S, Wakamatsu Y, Nagao Y, Hashimoto H, Bertin C, Mourot B, Schmidt C, Wilhelm D, Centanin L, Guiguen Y, Herpin A.

    BMC Biology   Vol. 16   page: 16   2018.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1186/s12915-018-0485-8

    Web of Science

  8. Axis Formation and Its Evolution in Ray-Finned Fish

    Hibi Masahiko, Takeuchi Masaki, Hashimoto Hisashi, Shimizu Takashi

    REPRODUCTIVE AND DEVELOPMENTAL STRATEGIES: THE CONTINUITY OF LIFE     page: 709 - +   2018

  9. Higher susceptibility to osmolality of the medaka (Oryzias latipes) mutants in orthologue genes of mammalian skin transglutaminases

    Watanabe Yuko, Furukawa Eri, Tatsukawa Hideki, Hashimoto Hisashi, Kamei Yasuhiro, Taniguchi Yoshihito, Hitomi Kiyotaka

    BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY   Vol. 82 ( 7 ) page: 1165 - 1168   2018

  10. Biochemical characterization of a medaka (Oryzias latipes) orthologue for mammalian Factor XIII and establishment of a gene-edited mutant Reviewed

    FEBS JOURNAL   Vol. 284 ( 17 ) page: 2843 - 2855   2017.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/febs.14153

    Web of Science

  11. Medaka and zebrafish contactin1 mutants as a model for understanding neural circuits for motor coordination

    Takeuchi Miki, Inoue Chikako, Goshima Akiko, Nagao Yusuke, Shimizu Koichi, Miyamoto Hiroki, Shimizu Takashi, Hashimoto Hisashi, Yonemura Shigenobu, Kawahara Atsuo, Hirata Yutaka, Yoshida Masayuki, Hibi Masahiko

    GENES TO CELLS   Vol. 22 ( 8 ) page: 723 - 741   2017.8

  12. Biochemical characterization of the medaka (Oryzias latipes) orthologue for mammalian tissue-type transglutaminase (TG2)

    Takada Yuki, Watanabe Yuko, Okuya Kazuho, Tatsukawa Hideki, Hashimoto Hisashi, Hitomi Kiyotaka

    BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY   Vol. 81 ( 3 ) page: 469 - 474   2017.3

  13. Biochemical characterization of the medaka (Oryzias latipes) orthologue for mammalian tissue-type transglutaminase (TG2). Reviewed

    Takada Y, Watanabe Y, Okuya K, Tatsukawa H, Hashimoto H, Hitomi K.

    Bioscience, Biotechnology, and Biochemistry   Vol. 81   page: 469-474   2017

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  14. Medaka and zebrafish contactin1 mutants as a model for understanding neural circuits for motor coordination.

    Takeuchi M, Inoue C, Goshima A, Nagao Y, Shimizu K, Miyamoto H, Shimizu T, Hashimoto H, Yonemura S, Kawahara A, Hirata Y, Yoshida M, Hibi M.

    Genes to Cells   Vol. 22   page: 723-741   2017

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  15. Biochemical characterization of a medaka (Oryzias latipes) orthologue for mammalian Factor XIII and establishment of a gene-edited mutant.

    Horimizu R, Ogawa R, Watanabe Y, Tatsukawa H, Kinoshita M, Hashimoto H, Hitomi K.

    FEBS Journal   Vol. 284   page: 2843-2855   2017

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  16. Osteocrin, a peptide secreted from the heart and other tissues, contributes to cranial osteogenesis and chondrogenesis in zebrafish. Reviewed

    Chiba A, Watanabe-Takano H, Terai K, Fukui H, Miyazaki T, Uemura M, Hashimoto H, Hibi M, Fukuhara S, Mochizuki N.

    Developmen   Vol. 144   page: 334-344   2017

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  17. Establishment of oct4:egfp transgenic and oct4:egfp /beta-actin:DsRed double transgenic medaka lines. Reviewed

    Yokota S, Matsuno R, Kato H, Hashimoto H, Kinoshita M, Yokoi H, Suzuki T.

    In Vitro Cellular and Developmental Biology-Animal   Vol. 52 ( 6 ) page: 646-653   2016

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s11626-016-0020-6

  18. What is a vertebrate pigment cell? Reviewed

    Schartl M, Larue L, Goda M, Bosenberg MW, Hashimoto H, Kelsh RN

    Pigment Cell and Melanoma Research     2015

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/pcmr.12409

  19. Biochemical characterization of medaka (Oryzias latipes) transglutaminases, OlTGK1 and OlTGK2, as Orthologues of human keratinocyte-type transglutaminase. Reviewed

    Kikuta A, Furukawa E, Ogawa R, Suganuma N, Saitoh M, Nishimaki T, Katsumura T, Oota H, Kawamoto T, Tatsukawa H, Hashimoto H, Hitomi K.

    PLoS ONE   Vol. 10 ( 12 ) page: e0144194   2015

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    DOI: 10.1371/journal.pone.0144194

  20. Positional cloning of three leucophore mutants indicates a close relation of leucophore and xanthophore in medaka. Reviewed

    Kimura T, Nagao Y, Hashimoto H, Yamamoto-Shiraishi Y, Yabe T, Takada S, Kinoshita M, Kuroiwa A, Naruse K.

    Proceedings of the National Academy of Sciences USA   Vol. 111   page: 7343-7348   2014.5

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    DOI: 10.1073/pnas.1311254111

  21. Sox5 functions as a fate switch in medaka pigment cell development. Reviewed

    Nagao Y, Suzuki T, Shimizu A, Kimura T, Seki R, Adachi T, Inoue C, Omae Y, Kamei Y, Hara I, Taniguchi Y, Naruse K, Wakamatsu Y, Kelsh RN, Hibi M, Hashimoto H

    PLoS genetics   Vol. 10 ( 4 ) page: e1004246   2014.4

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    DOI: 10.1371/journal.pgen.1004246

  22. Multiple pigment cell types contribute to the black, blue, and orange ornaments of male guppies (Poecilia reticulata). Reviewed

    Kottler VA, Koch I, Flötenmeyer M, Hashimoto H, Weigel D, Dreyer C.

    PLoS ONE   Vol. 9 ( 1 ) page: e85647   2014.1

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    DOI: 10.1371/journal.pone.0085647

  23. A protocol for adult somatic cell nuclear transfer in medaka fish (Oryzias latipes) with a high rate of viable clone formation. Reviewed

    Bubenshchikova E, Kaftanovskaya E, Adachi T, Hashimoto H, Kinoshita M, Wakamatsu Y.

    Cellular Reprogramming     2014

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    DOI: DOI: 10.1089/cell.2013.0004

  24. Taking striping up a notch. Invited Reviewed

    Goda M, Kelsh RN, Hashimoto H

    Pigment Cell and Melanoma Research   Vol. 27   page: 688-689   2014

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    DOI: 10.1111/pcmr.12288

  25. Derlin-1 and UBXD8 are engaged in dislocation and degradation of lapidated ApoB-100 at lipid droplets. Reviewed

    Suzuki M, Otsuka T, Ohsaki Y, Cheng J, Taniguchi T, Hashimoto H, Taniguchi H, Fujimoto T.

    Molecular Biology of the Cell   Vol. 23   page: 800-810   2012

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    DOI: 800-810

  26. The Medaka zic1/zic4 Mutant Provides Molecular Insights into Teleost Caudal Fin Evolution Reviewed

    Moriyama Y, Kawanishi T, Nakamura R, Tsukahara T, Sumiyama K, Suster ML, Kawakami K, Toyoda A, Fujiyama A, Yasuoka Y, Nagao Y, Sawatari E, Shimizu A, Wakamatsu Y, Hibi M, Taira M, Okabe M, Naruse K, Hashimoto H, Shimada A, Takeda H

    Current Biology   Vol. 22   page: 601-607   2012

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    DOI: 601-607

  27. Nuclear transfer of embryonic cell nuclei to non-enucleated eggs in zebrafish, Danio rerio. Invited Reviewed

    Hattori M, Hashimoto H, Bubenshchikova E, Wakamatsu Y.

    International Journal of Biological Sciences   Vol. 7 ( 4 ) page: 460-468   2011.4

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  28. Detection of vitellogenin incorporation into zebrafish oocytes by FITC fluorescence. Reviewed

    Matsuda Y, Ito Y, Hashimoto H, Yokoi H, Suzuki T.

    Reproductive Biology and Endocrinology   Vol. 9   page: 45   2011

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  29. Embryogenic staging of fugu, Takifugu rubripes, and expression profiles of aldh1a2 and aldh1a3. Reviewed

    Uji S, Kurokawa T, Hashimoto H, Kasuya T, Suzuki T.

    Development, Growth and Differentiation   Vol. 53   page: 715-725   2011

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  30. Dynein axonemal intermediate chain 2 is required for formation of the left-right body axis and kidney in medaka. Reviewed

    Nagao Y, Cheng J, Kamura K, Seki R, Maeda A, Nihei D, Koshida S, Wakamatsu Y, Fujimoto T, Hibi M, Hashimoto H.

    Developmental Biology   Vol. 347   page: 53-61   2010

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  31. Metamorphic pitx2 expression in the left habenula correlated with lateralization of eye-sidedness in flounder Reviewed

    Suzuki, T., Washio,Y., Aritaki, M., Fujinami, Y., Shimizu, D., Uji, S., and Hashimoto, H.

    Development, Growth & Differentiation   Vol. 51 ( 9 ) page: 797-808   2009.12

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  32. Cell growth promoting activity of fluid from eye sacs of bubble-eye goldfish (Carassius auratus). Reviewed

    Sawatari, E., Hashimoto, H., Matsumura, T., Iwata, Y., Yamamoto, N., Yokoyama, Y., and Wakamatsu, Y.

    Zoological Science   Vol. 26   page: 254-258   2009

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  33. Overexpression of the dominant-negative form of myostatin results in doubling of muscle-fiber number in transgenic medaka (Oryzias latipes). Reviewed

    Sawatari, E., Seki, R., Adachi, T., Hashimoto, H., Uji, S., Wakamatsu, Y., Nakata, T., and Kinoshita, M.

    Comp Biochem Physiol A Mol Integr Physiol   Vol. 155   page: 183-189   2009

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  34. *A murine model of neonatal diabetes mellitus in Glis3-deficient mice. Reviewed

    Watanabe, N., Hiramatsu, K., Miyamoto, R., Yasuda, K., Suzuki, N., Oshima, N., Kiyonari, H., Shiba, D., Nishio, S., Mochizuki, T., Yokoyama, T., Maruyama, S., Matsuo, S., Wakamatsu, Y., and Hashimoto, H.

    FEBS Letters   Vol. 583   page: 2108-2113   2009

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  35. *Polycystic kidney disease in the medaka (Oryzias latipes) pc mutant caused by a mutation in the Gli-similar3 (glis3) gene. Reviewed

    Hashimoto, H., Miyamoto, R., Watanabe, N., Shiba, D., Ozato, K., Inoue, C., Kubo, Y., Koga, A., Jindo, T., Narita, T., Naruse, K., Ohishi, K., Nogata, K., Shin-I, T., Asakawa, S., Shimizu, N., Miyamoto, T., Mochizuki, T., Yokoyama, T., Hori, H., Takeda, H., Kohara, Y., and Wakamatsu, Y.

    PLoS ONE   Vol. 4 ( 7 ) page: e6299   2009

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  36. *Kidney regeneration through nephron neogenesis in medaka. Reviewed

    Watanabe, N., Kato, M., Suzuki, N., Inoue, C., Fedorova, S., Hashimoto, H., Maruyama, S., Matsuo, S., and Wakamatsu, Y.

    Development Growth & Differentitation   Vol. 51   page: 135-143   2009

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  37. *Renal glomerulogenesis in medaka fish, Oryzias latipes. Reviewed

    Fedorova, S., Miyamoto, R., Harada, T., Isogai, S., Hashimoto, H., Ozato, K., and Wakamatsu, Y.

    Developmental Dynamics   Vol. 237   page: 2342-2352   2008

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  38. *Nuclear transplants from adult somatic cells generated by a novel method using diploidized eggs as recipients in medaka fish (Oryzias latipes). Reviewed

    Cloning and Stem Cells   Vol. 10   page: 443-452   2008

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  39. Embryogenesis and expression profile of charon and nodal-pathway genes in sinistral (Paralichthys olivaceus) and dextral (Verasper variegatus) flounders. Reviewed

    Hashimoto, H., Aritaki, M., Uozumi, K., Uji, S., Kurokawa, T., and Suzuki, T.

    Zoological Science   Vol. 24   page: 137-146   2007

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  40. Diploidized eggs reprogram adult somatic cell nuclei to pluripotency in nuclear transfer in medaka fish (Oryzias latipes). Reviewed

    Bubenshchikova, E., Kaftanovskaya, E., Motosugi, N., Fujimoto, T., Arai, K., Kinoshita, M., Hashimoto, H., Ozato K., and Wakamatsu, Y.

    Development Growth & Differentiation   Vol. 49 ( 9 ) page: 699-709   2007

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  41. 左ヒラメに右カレイの謎に迫る Invited

    鈴木徹,有瀧真人,宇治督,橋本寿史

    化学と生物   Vol. 45   page: 511-515   2007

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    Language:Japanese  

  42. Flounder and fugu have a single lefty gene that covers the functions of lefty1 and lefty2 of zebrafish during L-R patterning. Reviewed

    Hashimoto, H., Uji, S., Kurokawa, T., Washio., Y., and Suzuki, T.

    Gene   Vol. 387   page: 126-132   2007

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  43. cDNA cloning of Japanese oyster stress protein homologous to the mammalian 78-kDa glucose regulated protein and its induction by heatshock. Reviewed

    Yokoyama, Y., Hashimoto, H., Kubota, S., Kuriyama, A., Ogura, Y., Mizuta, S., Yoshinaka, R., and Toyohara, H.

    Fisheries Science   Vol. 72   page: 402-409   2006

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  44. Fish mesonephric model of polycystic kidney disease in medaka (Oryzias latipes) pc mutant Reviewed

    E. Mochizuki, K. Fukuta, T. Tada, T. Harada, N. Watanabe, S. Matsuo, H. Hashimoto, K. Ozato, and Y. Wakamatsu

    Kidney International   Vol. 68   page: 23-34   2005

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  45. ヒラメ・カレイの体の左右非対称性と内臓・脳の左右非対称性形成との関わり Invited

    鈴木徹、橋本寿史、有瀧真人、宇治督、黒川忠英

    日本動物育種学会誌   Vol. 33   page: 55-65   2005

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  46. Expression of HSP70 in response to heat-shock and its cDNA cloning from Mediterranean blue mussel. Reviewed

    Toyohara, H., Hosoi, M., Hayashi, I., Kubota, S., Hashimoto, H., and Yokoyama, Y.

    Fisheries Science   Vol. 71   page: 327-332   2005

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  47. The Cerberus/Dan-family protein Charon is a negative regulator of Nodal signaling during left-right patterning in zebrafish Reviewed

    H. Hashimoto, M. Rebagliati, N. Ahmad, O. Muraoka, T. Kurokawa, M. Hibi, and T. Suzuki

    Development   Vol. 131   page: 1741-1753   2004

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  48. Zinc finger protein too few controls the development of monoaminergic neurons Reviewed

    G. Levkowitz, J. Zeller, H. I. Sirotkin, D. French, S. Schilbach, H. Hashimoto, M. Hibi, W. S. Talbot, and A. Rosenthal

    Nature Neuroscience   Vol. 6   page: 28-33   2003

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  49. Identification of gastrin and multiple cholecystokinin genes in teleost. Reviewed

    Kurokawa, T., Suzuki, T., and Hashimoto, H.

    Peptides   Vol. 24   page: 227-235   2003

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  50. Differentiation of chondrocytes and scleroblasts during dorsal fin skeletogenesis in flounder larvae. Reviewed

    Suzuki, T., Haga, Y., Takeuchi, T., Uji, S., Hashimoto, H., and Kurokawa, T.

    Development Growth & Differentiation   Vol. 45   page: 435-448   2003

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  51. cDNA sequence and tissue expression of Fugu rubripes prion protein-like: a candidate for the teleost orthologue of tetrapod PrPs. Reviewed

    Suzuki, T., Kurokawa, T., Hashimoto, H., and Sugiyama, M.

    Biochemical and Biophysical Research Communications   Vol. 294   page: 912-917   2002

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  52. Isolation and characterization of a Japanese flounder clonal line, reversed, which exhibits reversal metamorphic left-right asymmetry. Reviewed

    Hashimoto, H., Mizuta, A., Okada, N., Suzuki, T., Tagawa, M., Tabata, K., Yokoyama, Y., Sakaguchi, M., Tanaka, M., and Toyohara, H.

    Mechanisms of Development   Vol. 111   page: 17-24   2002

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  53. The nuclear export signal (NES) found in the amino-terminal region of carp MEK1 and MKK6 is lacking in carp MKK4. Reviewed

    Hashimoto, H., Matsuo, Y., Yokoyama, Y., Toyohara, H., and Sakaguchi, M.

    Biochim. Biophys. Acta   Vol. 1575   page: 139-142   2002

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  54. 脊椎動物初期体軸形成の分子機構―ゼブラフィッシュからの知見 Invited

    日比正彦,清水貴史,橋本寿史,柳成林,山中庸次郎,平野俊夫

    小型魚類研究の新展開 (蛋白質核酸酵素増刊)   Vol. 45   page: 2720-2731   2000

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  55. Zebrafish Dkk1 functions in forebrain specification and axial mesendoderm formation Reviewed

    H. Hashimoto, M. Ito, Y. Yamanaka, S. Yamashita, T. Shimizu, L. Solnica-Krezel, M. Hibi, and T. Hirano

    Developmental Biology   Vol. 217   page: 138-152   2000

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  56. Cooperative roles of Bozozok/Dharma and Nodal-related proteins in the formation of the dorsal organizer in zebrafish Reviewed

    T. Shimizu, Y. Yamanaka, S. Ryu, H. Hashimoto, T. Yabe, T. Hirata, Y. Bae, M. Hibi, and T. Hirano

    Mechanisms of Development   Vol. 91   page: 293-303   2000

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  57. Identification of a nuclear export signal in MKK6, an activator of the carp p38 mitogen-activated protein kinases Reviewed

    H. Hashimoto, M. Fukuda, Y. Matsuo, Y. Yokoyama, E. Nishida, H. Toyohara, and M. Sakaguchi

    European Journal of Biochemistry   Vol. 267   page: 4362-4371   2000

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  58. Fezl: a novel zinc finger gene expressed in zebrafish forebrain Reviewed

    H. Hashimoto, T. Yabe, T. Hirata, T. Shimizu, Y. Bae, Y. Yamanaka, M. Hibi, and T. Hirano

    Mechanisms of Development   Vol. 97   page: 191-195   2000

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  59. Suppression of apoptosis of fish cells by acclimatization to hypertonicity Reviewed

    H. Hashimoto, Y. Matsuo, K. Takeuchi, Y. Yokoyama, H. Toyohara, and M. Sakaguchi

    Fisheries Science   Vol. 65   page: 145-149   1999

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  60. cDNA cloning of heat-inducible HSP70, a 70.6kDa heat shock protein, in Japanese Flounder Paralichtys olivaceus Reviewed

    Y. Yokoyama, H. Hashimoto, S. Kubota, M. Kinoshita, H. Toyohara, M. Sakaguchi, M. Tanaka, T. Seikai, and M. Kanamori

    Fisheries Science   Vol. 64   page: 964-968   1998

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  61. Cell growth of fish cultures in hyper- and hypoosmotic media Reviewed

    H. Hashimoto, K. Takeuchi, Y. Matsuo, Y. Yokoyama, H. Toyohara, and M. Sakaguchi

    Fisheries Science   Vol. 64   page: 350-35   1998

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  62. Existence of two isoforms of extracellular-signal regulated kinase in fish Reviewed

    H. Hashimoto, Y. Yokoyama, Y. Matsuo, H. Toyohara, M. Kohno, and M. Sakaguchi

    Journal of Biochemistry   Vol. 123   page: 1031-1035   1998

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  63. Induction of apoptosis in fish cells by hypertonic stress Reviewed

    H. Hashimoto, Y. Matsuo, Y. Yokoyama, H. Toyohara, and M. Sakaguchi

    Fisheries Science   Vol. 64   page: 820-825   1998

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  64. Comlementary DNA cloning of HSC71, a 71 kDa heat-shock cognate protein, in Japanese Flounder Paralichtys olivaceus Reviewed

    Y. Yokoyama, H. Hashimoto, S. Kubota, M. Kinoshita, H. Toyohara, M. Sakaguchi, and M. Kanamori

    Fisheries Science   Vol. 64   page: 388-392   1998

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    Language:English   Publishing type:Research paper (scientific journal)  

  65. Structure and expression of carp mitogen-activated protein kinases homologous to mammalian JNK/SAPK Reviewed

    H. Hashimoto, Y. Matsuo, Y. Yokoyama, H. Toyohara, and M. Sakaguchi

    Journal of Biochemistry   Vol. 122   page: 381-386   1997

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  66. Effects of carp (Cyprinus carpio L.) serum on the growth of goldfish (Carassius auratus L.) fin cells in early passage Reviewed

    H. Hashimoto, H. Toyohara, Y. Yokoyama, M. Sakaguchi, K. Ozato, and Y. Wakamatsu

    Journal of Fish Biology   Vol. 50   page: 201-207   1997

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  67. Molecular cloning and growth hormone-regulated gene expression of carp insulin-like growth factor-I Reviewed

    H. Hashimoto, S. Mikawa, E. Takayama, Y. Yokoyama, H. Toyohara, and M. Sakaguchi

    Biochemistry and Molecular Biology International   Vol. 41   page: 877-886   1997

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  68. Transgenic expression of L-gulono--lactone oxidase in medaka (Oryzias latipes), a teleost fish that lacks this enzyme necessary for L-ascorbic acid biosythesis Reviewed

    H. Toyohara, T. Nakata, K. Touhata, H. Hashimoto, M. Kinoshita, M. Sakaguchi, M. Nishikimi, K. Yagi, Y. Wakamatsu, and K. Ozato

    Biochemical and Biophysical Research Communications   Vol. 223   page: 650-653   1996

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    Language:English   Publishing type:Research paper (scientific journal)  

  69. Generation of germ-line chimeras in medaka (Oryzias latipes) Reviewed

    Y. Wakamatsu, K. Ozato, H. Hashimoto, M. Kinoshita, M. Sakaguchi, T. Iwamatsu, Y. Hyodo-Taguchi, and H. Tomita

    Molecular Marine Biology and Biotechnology   Vol. 2   page: 325-332   1993

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    Language:English   Publishing type:Research paper (scientific journal)  

▼display all

Books 13

  1. ゼブラフィッシュ実験ガイド

    日比正彦、清水貴史、橋本寿史、井原邦夫( Role: Contributor ,  第17章 実験に必要な手続き)

    2020  ( ISBN:978-4-254-17173-0

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    Language:Japanese Book type:Textbook, survey, introduction

  2. 魚類発生学の基礎

    橋本寿史、清水貴史、日比正彦(第5章 体軸形成)

    恒星社厚生閣  2018.9  ( ISBN:9784769914853

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    Total pages:212   Language:Japanese Book type:Textbook, survey, introduction

  3. 魚類発生学の基礎

    清水貴史、橋本寿史、日比正彦( Role: Joint author ,  第7章 神経誘導)

    恒星社厚生閣  2018.9  ( ISBN:9784769914853

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    Total pages:212   Language:Japanese Book type:Textbook, survey, introduction

  4. 魚類発生学の基礎

    清水貴史、橋本寿史、日比正彦( Role: Joint author ,  第6章 中胚葉誘導)

    恒星社厚生閣  2018.9  ( ISBN:9784769914853

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    Total pages:212   Language:Japanese Book type:Textbook, survey, introduction

  5. めだかの学校 山本時男博士と日本のメダカ研究 宗宮弘明、足立 守、野崎ますみ、成瀬 清編

    橋本寿史( Role: Contributor ,  第II部 メダカ研究の最近 第2章 メダカの色について考える)

    あるむ  2018.1  ( ISBN:978-4-86333-133-4

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    Total pages:314   Responsible for pages:111-133   Language:Japanese Book type:General book, introductory book for general audience

  6. Kidney development, regeneration and polycystic kidney disease in medaka in Medaka: model for organogenesis, human disease and evolution (ed. Naruse K, Tanaka M, Takeda H.)

    Hisashi Hashimoto( Role: Joint author)

    Springer  2011  ( ISBN:978-4-431-92690-0

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    Language:English

  7. Regenerative Nephrology

    Goligorsky MS.( Role: Joint author)

    Academic Press  2010 

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    Language:English

    Glomerulogenesis and de novo nephrogenesis in medaka fish: an evolutionary approach

  8. Medaka: Biology, Management, and Experimental Protocols ed. Kinoshita, M., Murata, K., Naruse, K. and Tanaka, M.

    Hisashi Hashimoto( Role: Sole author ,  Strain preservation and related techniques)

    Blackwell  2008 

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    Responsible for pages:101-103   Language:English Book type:Scholarly book

    DOI: https://doi.org/10.1002/9780813818849.ch4

  9. Medaka: Biology, Management, and Experimental Protocols ed. Kinoshita, M., Murata, K., Naruse, K. and Tanaka, M.

    Hisashi Hashimoto( Role: Sole author ,  Looking at adult medaka: kidney)

    Blackwell  2008 

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    Responsible for pages:157-160   Language:English Book type:Scholarly book

    DOI: https://doi.org/10.1002/9781119575399.ch3

  10. Medaka: Biology, Management, and Experimental Protocols ed. Kinoshita, M., Murata, K., Naruse, K. and Tanaka, M.

    Hisashi Hashimoto( Role: Sole author ,  Looking at adult medaka: see-through medaka)

    Blackwell  2008 

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    Responsible for pages:124-125   Language:English Book type:Scholarly book

    DOI: https://doi.org/10.1002/9781119575399.ch3

  11. Medaka: Biology, Management, and Experimental Protocols ed. Kinoshita, M., Murata, K., Naruse, K. and Tanaka, M.

    Hashimoto H, Bubenshchikova E, Kaftanovskaya E, Wakamatsu YHisashi Hashimoto( Role: Joint author ,  Advanced techniques: nuclear transplantation)

    Blackwell  2008 

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    Responsible for pages:367-370   Language:English Book type:Scholarly book

    DOI: https://doi.org/10.1002/9780813818849.ch10

  12. Medaka: Biology, Management, and Experimental Protocols ed. Kinoshita, M., Murata, K., Naruse, K. and Tanaka, M.

    Hisashi Hashimoto( Role: Sole author ,  Looking at medaka embryos: kidney)

    Blackwell  2008 

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    Responsible for pages:227-229   Language:English Book type:Scholarly book

    DOI: https://doi.org/10.1002/9781119575399.ch4

  13. *泳ぐDNA

    猿渡敏郎編( Role: Joint author)

    東海大学出版会  2007.12 

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    Language:Japanese

▼display all

MISC 4

  1. メダカのデザイン 基本のルール Invited

    成瀬 清、橋本寿史

    アクアライフ合本     page: 54 - 61   2019

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    Authorship:Last author   Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)  

  2. メダカのデザイン 基本のルール2 Invited

    成瀬 清、橋本寿史

    月刊アクアライフ   Vol. 472   page: 22 - 25   2018

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    Authorship:Last author   Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)  

  3. メダカのデザイン 基本のルール Invited

    成瀬 清、橋本寿史

    月刊アクアライフ   Vol. 466   page: 18 - 21   2018

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    Authorship:Last author   Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)  

  4. 魚類IGF-Iの構造と機能 Invited

    橋本寿史、豊原治彦

    月刊海洋   Vol. 27 ( 5 ) page: 291 - 298   1995

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    Authorship:Lead author   Language:Japanese   Publishing type:Rapid communication, short report, research note, etc. (scientific journal)  

Presentations 103

  1. CMP-Sia synthetase and sialylation are essential for embryogenesis in medaka

    Wu D, Fujita A, Hashimoto H, Hibi M, Taniguchi Y, Kamei Y, Sato C, Kitajima K

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    Event date: 2020.11

    Language:Japanese  

    Country:Japan  

  2. Hypothesis for variegated body pigmentation based on aberrant regulation of PKA activity. International coauthorship

    Goda M, Wakamatsu Y, Kobayashi K, Inoue C, Villareal M, Isoda, H, Ohtani K, Nishimaki T, Oota H, Ogawa M, Kimura T, Naruse K, Kelsh RN, Hibi M, Hashimoto H

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    Event date: 2020.11

    Language:Japanese  

    Country:Japan  

  3. Biochemical phenotypes of the knockout medaka for the α2,6-sialyltransefrases I and II genes

    Omoto T, Wu D, Hashimoto H, Hibi M, Hane M, Sato C, Kitajima K

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    Event date: 2020.11

    Language:Japanese  

    Country:Japan  

  4. Roles of Sox9b in medaka pigment cell development

    Tunogai, Y., Hibi, M., Hashimoto, H.

    第53回日本発生生物学会大会 

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    Event date: 2020.5

    Language:English   Presentation type:Oral presentation (general)  

  5. Pax3b and Pax7a have sequential function to regulate fate choice of pigment cells in medaka

    Hashimoto H, Watakabe I, Miyadai M, Takada H, Kimura T, Naruse K, Higashijima S, Hibi M

    第53回日本発生生物学会大会  2019.5 

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    Event date: 2020.5

    Language:English   Presentation type:Oral presentation (general)  

  6. メダカ黒斑変異体Variegatedはヒトカーニー複合の皮膚病態モデルである

    橋本 寿史、合田 真、静 隆志、小林 健一、三木 千晶、井上 慎子、Villareal Myra、礒田 博子、大谷 勝己、西槇 俊之、木村 哲晃、成瀬 清、日比正彦

    第90回日本動物学会  2019.9 

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    Event date: 2019.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:大阪   Country:Japan  

  7. Pax3 and Pax7 sequentially regulate fate choice of pigment cells in medaka and zebrafish International coauthorship

    Miyadai M, Takada H, Kimura T, Tsunogai Y, Kelsh R, Naruse K, Hibi M, Hashimoto H

    2019.5 

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    Event date: 2019.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  8. HMG型転写因子Sox9bはSox10と協調してメダカの色素胞発生を促進する

    橋本 寿史、宮台 元裕、日比 正彦

    平成31年度日本動物学会中部支部大会  2018.12 

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    Event date: 2018.12

    Language:Japanese   Presentation type:Poster presentation  

    Venue:名古屋   Country:Japan  

  9. メダカとゼブラフィッシュの比較発生学研究〜色素細胞の発生における運命決定メカニズム Invited

    橋本寿史、成瀬清

    第41回日本分子生物学会ワークショップ「生物種横断的研究の進展とバイオリソースの役割」  2018.11.28 

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    Event date: 2018.11

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    Venue:横浜   Country:Japan  

  10. bHLH型転写制御因子MitfおよびTfecはメダカの黒色素細胞の発生を冗長的に促進する International coauthorship International conference

    橋本 寿史、木村 哲晃、宮台 元裕、長尾 勇佑、ロバート ケルシュ、成瀬 清、日比 正彦

    第89回日本動物学会年会  2018.9 

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    Event date: 2018.9

    Language:Japanese   Presentation type:Poster presentation  

    Venue:札幌   Country:Japan  

  11. Pax3 and Pax7 differentially regulate fate choice of pigment cells in zebrafish and medaka International coauthorship

    Miyadai M, Takada H, Kimura T, Kelsh RN, Naruse K, Hibi M, Hashimoto H

    2018.8.25 

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    Event date: 2018.8

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  12. Mitf and Tfec transcription factors redundantly function in melanocyte development in medaka International coauthorship

    Hashimoto H, Kimura T, Miyadai M, Nagao Y, Kelsh RN, Naruse K, Hibi M

    2018.8.25 

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    Event date: 2018.8

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  13. Redundant functions of Mitf/Tfec family transcription factors regulate melanocyte development in medaka International coauthorship

    Hashimoto H, Kimura T, Miyadai M, Nagao Y, Kelsh RN, Naruse K, Hibi M

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    Event date: 2018.6

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  14. Pax3とPax7は色素細胞の運命決定を制御する

    宮台元裕、髙田広之、木村哲晃、成瀬 清、ロバートケルシュ、日比正彦、橋本寿史

    第88回日本動物学会年会 

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    Event date: 2017.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:富山   Country:Japan  

  15. Pax3 and Pax7 differentially regulate fate choice of pigment cells in zebrafish. International conference

    Miyadai M, Takada H, Kelsh R, Hibi M, Hashimoto H

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    Event date: 2017.5

    Language:English   Presentation type:Poster presentation  

  16. Sox5 modulates Sox10 function in pigment cell fate specification in medaka and zebrafish. International coauthorship International conference

    Nagao Y, Takada H, Miyadai M, Seki R, Kamei Y, Hara I, Taniguchi Y, Naruse K, Hibi M, Kelsh R, Hashimoto H

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    Event date: 2017.5

    Language:English   Presentation type:Poster presentation  

    Venue:東京  

  17. A variegated medaka mutant Va: a model of human Carney complex. International coauthorship

    Goda M, Shizuka T, Inoue C, Nishikawa K, Miki C, Kimura T, Villareal MO, Isoda H, Naruse K, Hibi M, Wakamatsu Y, Hashimoto H

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    Event date: 2016.11

    Language:Japanese   Presentation type:Poster presentation  

  18. Sox5 modulates Sox10-meiated pigment cell fate specification in medaka and zebrafish. International coauthorship International conference

    Nagao Y, Takada H, Miyadai M, Seki R, Kamei Y, Hara I, Taniguchi Y, Naruse K, Hibi M, Kelsh RN, Hashimoto H

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    Event date: 2016.8

    Language:Japanese   Presentation type:Poster presentation  

  19. モデル生物としてメダカを用いたタンパク質架橋化酵素の生理的機能解析 International conference

    堀水里麻、小河亮太、橋本寿史、木下政人、辰川英樹、人見清隆

    第38回日本分子生物学会年会・第88回日本生化学会大会合同大会 

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    Event date: 2015.12

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:神戸  

  20. Generation of zebrafish sox5 mutant by CRISPR for understanding the mechanism of fate specification of pigment cells in teleost.

    Takada H, Nagao Y, Adachi T, Hibi M, Kelsh RN, Hashimoto H.

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    Event date: 2015.9

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  21. Generation of zebrafish sox5 mutant by CRISPR for understanding the mechanism of fate specification of pigment cells in teleost.

    Takada H, Nagao Y, Adachi T, Hibi M, Kelsh RN, Hashimoto H

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    Event date: 2015.9

    Language:Japanese   Presentation type:Poster presentation  

  22. モデル生物としてメダカのタンパク質架橋化酵素ファミリーとその機能に関する解析

    高田佑紀、奥谷冬穂、木下政人、橋本寿史、辰川英樹、人見清隆

    日本農芸化学会中部支部例会 

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    Event date: 2015.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:射水  

  23. Roles of sox10 and its possible interaction with sox5 in pigment cell development. International conference

    Nagao Y, Takada H, Seki R, Kamei Y, Hara I, Taniguchi Y, Naruse K, Hibi M, Kelsh RN, Hashimoto H.

    European Society for Pigment Cell Research 

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    Event date: 2015.9

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  24. Roles of Sox10 and its possible interaction with Sox5 in pigment cell development. International conference

    Nagao Y, Takada H, Seki R, Kamei Y, Hara I, Taniguchi Y, Naruse K, Hibi M, Kelsh RN, Hashimoto H.

    7th European Zebrafish Meeting 

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    Event date: 2015.6 - 2015.7

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  25. Generation of zebrafish sox5 mutant by CRISPR for understanding the mechanism of fate specification of pigment cells in teleost. International conference

    Takada H, Nagao Y, Adachi T, Hibi M, Kelsh RN, Hashimoto H

    7th European Zebrafish Meeting 

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    Event date: 2015.6 - 2015.7

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  26. Roles of sox10 and its possible interaction with sox5 in pigment cell development of medaka.

    Nagao Y, Takada H, Seki R, Kamei Y, Hara I, Kimura T, Taniguchi Y, Naruse K, Kelsh RN, Hibi M, Hashimoto H.

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    Event date: 2015.6

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  27. Roles of sox10 and its genetic interaction with sox5 in pigment cell development.

    Nagao Y, Takada H, Seki R, Kamei Y, Hara I, Kimura T, Taniguchi Y, Naruse K, Kelsh RN, Hibi M, Hashimoto H.

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    Event date: 2014.9

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  28. Sox5 controls a fate choice during pigment cell development in medaka.

    Nagao Y, Adachi T, Shimizu A, Seki R, Inoue C, Kamei Y, Hara I, Kimura T, Taniguchi Y, Naruse K, Kelsh RN, Wakamatsu Y, Hibi M, Hashimoto H

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    Event date: 2014.5

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  29. Sox5 functions as a fate switch in medaka pigment cell development. International conference

    Hashimoto H

    2nd Strategical Meeting for Medaka Research 

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    Event date: 2014.4

    Language:English   Presentation type:Oral presentation (general)  

    Country:Spain  

  30. 色素細胞をモデルとした細胞運命決定機構の解析

    橋本 寿史

    基礎生物学研究所重点共同利用研究シンポジウム「メダカを使った解析パイプライン〜ヒト疾患モデルとしてのメダカ:コンディショナルKOなどを使った多面的解析系の確立〜」 

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    Event date: 2014.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:岡崎   Country:Japan  

  31. メダカ色素細胞分化におけるSox5の役割

    長尾勇佑、橋本寿史

    第84回日本動物学会年会、第9回色素細胞シンポジウム「お魚大会」 

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    Event date: 2013.9

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    Venue:岡山   Country:Japan  

  32. Sox5 is involved in fate specification of pigment cells in medaka.

    Nagao Y, Adachi T, Shimizu A, Seki R, Inoue C, Kamei Y, Hara I, Kimura T, Taniguchi Y, Naruse K, Kelsh RN, Wakamatsu Y, Hibi M, Hashimoto H

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    Event date: 2013.9

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  33. Sox5 is involved in fate specification of pigment cells in medaka.

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    Event date: 2013.5

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  34. メダカSox5は色素細胞の運命決定に関与する

    長尾勇佑、足立朋子、清水厚志、関 良子、井上慎子、亀井保博、原 郁代、木村哲晃、谷口善仁、成瀬 清、ロバート・ケルシュ、若松佑子、日比正彦、橋本寿史

    第35回日本分子生物学会年会 

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    Event date: 2012.12

    Language:Japanese   Presentation type:Poster presentation  

    Venue:福岡   Country:Japan  

  35. Sox5 is involved in fate specification of pigment cells in medaka.

    Nagao Y, Adachi T, Shimizu A, Seki R, Inoue C, Kamei Y, Hara I, Taniguchi Y, Naruse K, Kelsh RN, Wakamatsu Y, Hibi M, Hashimoto H.

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    Event date: 2012.9

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  36. 細胞表面α2,6-結合シアル酸残基はメダカ初期発生の進行に必要である

    丸山恵美、田嶋克枝、ラニィ・チャン、足立朋子、橋本寿史、日比正彦、佐藤ちひろ、北島 健

    第83回日本動物学会年会 

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    Event date: 2012.9

    Language:English   Presentation type:Poster presentation  

    Venue:豊中   Country:Japan  

  37. Sox5 regulates the development of neural crest-derived pigment cells in medaka and zebrafish. International conference

    Adachi T, Nagao Y, Chau V, Hibi M, Kelsh RN, Hashimoto H.

    The 17th Meeting of the European Society for Pigment Cell Research 

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    Event date: 2012.9

    Language:English   Presentation type:Poster presentation  

  38. Sox5 is involved in fate specification of pigment cell in medaka. International conference

    Nagao, Y., Adachi, T., Shimizu, A. Seki, R., Inoue, C., Kamei, Y., Hara, I., Taniguchi, Y., Naruse, K., Kelsh, R.N., Wakamatsu, Y., Hibi, M., and Hashimoto, H.

    10th International Conference on Zebrafish Development and Genetics 

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    Event date: 2012.6

    Language:English   Presentation type:Poster presentation  

    Country:United States  

  39. Sox5 is involved in fate specification of pigment cells in medaka.

    Nagao Y, Adachi T, Shimizu A, Seki R, Inoue C, Kamei Y, Hara I, Taniguchi Y, Naruse K, Kelsh RN, Wakamatsu Y, Hibi M, Hashimoto H.

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    Event date: 2012.5

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  40. Sox5 controls pigment cell development from the neural crest. International conference

    Adachi T, Nagao Y, Chau V, Hibi M, Kelsh RN, Hashimoto H

    British Society for Developmental Biology, British Society for Cell Biology and Japanese Society of Developmental Biologists Joint Spring Meeting 

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    Event date: 2012.4

    Language:English   Presentation type:Poster presentation  

    Country:United Kingdom  

  41. Pigment specification in medaka.

    Hashimoto H, Adachi T, Nagao Y, Kelsh RN, Hibi M.

    GCOE International Symposium- Formation and Function of Brain Networks: From Genes to Behavior. 

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    Event date: 2012.1

    Language:English   Presentation type:Symposium, workshop panel (nominated)  

    Country:Japan  

  42. Roles of a SoxD gene sox5 and its genetic interaction with SoxE genes in pigment cell development in medaka.

    Nagao Y, Adachi T, Shimizu A, Seki R, Inoue C, Kamei Y, Hara I, Taniguchi Y, Naruse K, Kelsh NR, Wakamatsu Y, Hibi M, Hashimoto H.

    GCOE International Symposium- Formation and Function of Brain Networks: From Genes to Behavior. 

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    Event date: 2012.1

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  43. Sox5 is involved in fate specification of pigment cell in medaka.

    Nagao Y, Adachi T, Shimizu A, Seki R, Inoue C, Kamei Y, Hara I, Taniguchi Y, Naruse K, Kelsh NR, Wakamatsu Y, Hibi M, Hashimoto H

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    Event date: 2011.12

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  44. Visualization of oct3/4-expression cells during medaka organ regeneration.

    Hashimoto H, Adachi T, Seki R, Sawatari E, Hibi M, Suzuki T

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    Event date: 2011.12

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  45. Roles of a SoxD gene sox5 and its genetic interaction with SoxE genes in pigment cell development. International conference

    Nagao Y, Adachi T, Shimizu A, Seki R, Inoue C, Kamei Y, Hara I, Taniguchi Y, Naruse K, Kelsh NR, Wakamatsu Y, Hibi M, Hashimoto H.

    National BioResource Project-Media- The1st Strategic Meeting for Medaka Research 

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    Event date: 2011.11

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  46. 白色素胞を異所的に過形成するメダカ変異体ml-3

    長尾勇佑、足立朋子、清水厚志、関 良子、井上慎子、亀井保博、原 郁代、谷口善仁、成瀬 清、ロバート・ケルシュ、若松佑子、日比正彦、橋本寿史

    第82回日本動物学会 

     More details

    Event date: 2011.9

    Language:Japanese   Presentation type:Poster presentation  

    Venue:旭川   Country:Japan  

  47. メダカ初期発生におけるシアロ糖鎖の重要性の検証

    丸山恵実、足立朋子、橋本寿史、日比正彦、佐藤ちひろ、北島 健

    第82回日本動物学会 

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    Event date: 2011.9

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  48. Roles of a SoxD gene sox5 and its genetic interaction with SoxE genes in pigment cell development

    Nagao Y, Adachi T, Shimizu A, Seki R, Inoue C, Kamei Y, Hara I, Taniguchi Y, Naruse K, Kelsh NR, Wakamatsu Y, Hibi M, Hashimoto H.

     More details

    Event date: 2011.9

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  49. TILLING screening for medaka mutants supported by NBRP medaka

    Hashimoto, H.

     More details

    Event date: 2011.9

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  50. Visualization of oct3/4-expression cells in medaka.

    Adachi T, Seki R, Sawatari E, Hibi M, Suzuki T, Hashimoto H.

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    Event date: 2011.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  51. A novel medaka mutant Da-2 showing a phenotype similar to Double-anal fin.

    Nagao Y, Sawatari E, Shimizu A, Furutani-Seiki M, Fedorova S, Takeda H, Wakamatsu Y, Hibi M, Hashimoto H.

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    Event date: 2011.5

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  52. Left-sided expression of pitx2 at dorsal diencephalon and gut is maintained throughout larval development in flounders for metamorphic morphogenesis.

    Kondo D, Fujinami Y, Uji S, Hashimoto H, Yokoi H, Suzuki T.

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    Event date: 2011.5

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  53. Expression analysis of nervous system marker genes reveals unique asymmetry formation of diencephalon in flounder larvae, correlated with one eye migration.

    5) Washio Y, Aritaki M, Fujinami Y, Simizu D, Uji S, Hashimoto H, Suzuki T.

     More details

    Event date: 2010.12

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  54. ヒラメ・カレイ類の左右非対称性を制御するpitx2の変態期再発現と、再発現に関連する左特異的エンハンサー内の核受容体応答配列

    鈴木徹、近藤大地、ウ ショーミン、横井勇人、宇治督、橋本寿史

    第33回日本分子生物学会・第83回日本生化学会合同大会 

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    Event date: 2010.12

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  55. メダカバイオリソースの技術的サポート2(TILLING、IR-LEGO、Cre/FLP-driver lineの作製)

    浅川修一、尾田正二、亀井保博、北野健、木下政人、清水厚志、新屋みのり、竹内秀明、谷口善仁、出口友則、殿山泰弘、成瀬清、橋本寿史

    第15回小型魚類研究会 

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    Event date: 2010.9

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  56. メダカバイオリソースの技術的サポート(メダカゲノムシークエンスの精度向上と新規ゲノムブラウザーの開発)

    浅川修一、尾田正二、亀井保博、北野健、木下政人、清水厚志、新屋みのり、竹内秀明、谷口善仁、出口友則、殿山泰弘、成瀬清、橋本寿史

    第15回小型魚類研究会 

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    Event date: 2010.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  57. Dynein axonemal intermediate chain 2 is required for formation of the left-right body axis and kidney in medaka. International conference

    9th International Conference on Zebrafish Development and Genetics. 

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    Event date: 2010.6

    Language:English   Presentation type:Poster presentation  

  58. Excessive and ectopic development of embryonic leucophores in medaka ml-3 mutant is caused by sox5 mutation. International conference

    9th International Conference on Zebrafish Development and Genetics. 

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    Event date: 2010.6

    Language:English   Presentation type:Poster presentation  

  59. メダカの運動性繊毛とPKD

    橋本寿史

    第9回PKD研究会 

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    Event date: 2009.12

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  60. *メダカ突然変異体をモデルとした腎繊毛異常症=多発性嚢胞腎の研究

    橋本寿史

    ワークショップ「繊毛の形成機構と多彩な機能」、第32回日本分子生物学会年会 

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    Event date: 2009.12

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  61. メダカmii変異体の解析:ヒトPCDのモデル生物へ向けて

    長尾勇佑、前田礼、程晶磊、加村啓一郎、二瓶大地、越田澄人、武田洋幸、藤本豊士、若松佑子、日比正彦、橋本寿史

    第15回小型魚類研究会 

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    Event date: 2009.9

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  62. *Medaka mii mutant as a model for human primary ciliary dyskinesia

     More details

    Event date: 2009.5

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  63. *A novel medaka mutant (Da-2) showing mirror-image duplication of the trunk-tail region.

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    Event date: 2009.5

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  64. *Detailed analysis of clonal characteristics arising in medaka nuclear transplants during transfer of somatic cell nuclei to non-enucleated diploidized eggs.

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    Event date: 2009.5

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  65. Glis3欠損マウスおよびメダカと繊毛

    橋本寿史、若松佑子

    第8回PKD研究会 

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    Event date: 2008.12

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

  66. メダカ左右軸形成異常変異体miiの同定と解析

    長尾勇佑、前田礼、渡辺直樹、吉田智也、橋本寿史、若松佑子、加村啓一郎、二瓶大地、越田澄人、武田洋幸

    第31回日本分子生物学会年会・第81回日本生化学会大会合同大会 

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    Event date: 2008.12

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  67. Transgenic medaka overexpressing dominant-negative form of myostatin, a counterpart of the double muscle mutation in cattle. International conference

    5th World Fisheries Congress 

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    Event date: 2008.10

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  68. キンギョ水泡眼水疱内液の細胞増殖促進効果および未受精卵保存液としての利用

    猿渡悦子、松村貴晴、橋本寿史、岩田靖宏、山本直生、若松佑子

    第79回日本動物学会年会 

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    Event date: 2008.9

    Language:Japanese   Presentation type:Poster presentation  

  69. *メダカ体色変異体の色素胞形成異常と原因遺伝子

    橋本寿史、若松佑子

    第5回色素細胞シンポジウム「動物における色素産生制御機構の新展開」、第79回日本動物学会年会 

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    Event date: 2008.9

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  70. 二倍体化卵を用いた新しいメダカ核移植法におけるドナー核の細胞周期

    カフタノフスカヤ エレナ、ブベンシコバ エカテリナ、足立朋子、橋本寿史、木下政人、若松佑子

    第79回日本動物学会年会 

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    Event date: 2008.9

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  71. Localization of left-sided pitx2 expression in flounder larval diencephalon and analysis of succeeding asymmetric development of brain and optic nerves.

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    Event date: 2008.5

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  72. Utilization of the fluid from eye sacs of Bubble-Eye Goldfish (Carassius auratus).

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    Event date: 2008.5

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  73. 腎疾患モデルとしてのメダカ

    橋本寿史、若松佑子

    サテライトワークショップ「多分野で活躍する小型魚類」、第41回日本発生生物学会年会 

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    Event date: 2008.5

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  74. Polycystic kidney disease in medaka pc mutant is caused by a mutation in gli-similar3 (glis3) gene. International conference

    The 4th Aquatic Animal Models of Human Disease Conference 

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    Event date: 2008.1

    Language:English   Presentation type:Poster presentation  

  75. A study of the correlation between the cell cycle phases of recipient eggs and successful development of nuclear transplants generated by adult somatic cell nuclear transfer in medaka (Oryzias latipes). International conference

    The 4th Aquatic Animal Models of Human Disease Conference 

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    Event date: 2008.1

    Language:English   Presentation type:Poster presentation  

  76. メダカおよびマウスにおけるpc/GLIS3突然変異の表現型

    橋本寿史、渡辺直樹、若松佑子

    第7回PKD研究会 

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    Event date: 2007.9

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  77. 胞胚期細胞核の付活卵への移植によるゼブラフィッシュ核移植個体の作製

    服部学、橋本寿史、エカテリーナ・ブベンシコバ、若松佑子

    第78回日本動物学会年会 

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    Event date: 2007.9

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  78. メダカにおけるネフロン新生を介した腎臓再生の可能性

    渡辺直樹、加藤光博、橋本寿史、尾里建二郎、若松佑子

    第40回日本発生生物学会年会 

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    Event date: 2007.5

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  79. ヒラメ間脳上部左側でのpitx2再発現に続いて起こる頭部および遊泳行動の非対称性形成

    鷲尾洋平、有瀧真人、藤浪裕一朗、橋本寿史、鈴木徹

    第40回日本発生生物学会年会 

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    Event date: 2007.5

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  80. 多発性嚢胞腎を発症するメダカpc変異体の原因遺伝子の同定

    橋本寿史、宮本理恵子、渡辺直樹、久保優子、古賀章彦、神藤智子、成田貴則、成瀬清、大石加寿子、野方恵子、新井理、小原雄治、武田洋幸、堀寛、若松佑子

    日本分子生物学会2006フォーラム 

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    Event date: 2006.12

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  81. メダカの前腎および中腎の発生

    橋本寿史、宮本理恵子、スヴェトラーナ・フェドロバ、原田智弘、平松健太郎、尾里建二郎、若松佑子

    第12回小型魚類研究会 

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    Event date: 2006.9

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  82. メダカ多発性嚢胞腎変異体原因遺伝子pcの機能解析

    橋本寿史、若松佑子

    第6回PKD研究会 

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    Event date: 2006.9

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  83. 多発性嚢胞腎メダカの開発

    宮本兼玄、橋本整司、望月俊雄、小池隆夫、橋本寿史、尾里建二郎、若松佑子

    第6回PKD研究会 

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    Event date: 2006.9

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  84. ヒラメ・カレイでは眼の非対称性形成開始時に間脳上部左側でpitx2が再発現する

    鈴木徹、橋本寿史、有瀧真人、宇治督、黒川忠英

    第39回日本発生生物学会年会(広島) 

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    Event date: 2006.5

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  85. メダカ多発性嚢胞腎原因遺伝子pcの変異領域の同定とアンチセンスオリゴによるノックダウン

    渡辺直樹、宮本理恵子、古賀章彦、尾里建二郎、若松佑子、橋本寿史

    第39回日本発生生物学会年会 

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    Event date: 2006.5

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  86. ヒラメ・カレイの片側眼球の移動に伴う脳の非対称性の形成とpitx2の新たな発現

    鈴木徹、橋本寿史、有瀧真人、宇治督、黒川忠英

    第28回日本分子生物学会年会 

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    Event date: 2005.12

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  87. Ogon/Sizzledによる背側化の分子機構

    村岡修、矢部泰二郎、橋本寿史、日比正彦

    第28回日本分子生物学会年会 

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    Event date: 2005.12

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  88. Analysis of medaka mutants with left-right axis abnormality.

    International Symposium on Standardization of Medaka Bioresources 

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    Event date: 2005.11

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  89. Development of medaka pronephros and mesonephros.

    International Symposium on Standardization of Medaka Bioresources 

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    Event date: 2005.11

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  90. Three-dimensional reconstruction of pronephros and mesonephros in medaka.

    International Symposium on Standardization of Medaka Bioresources 

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    Event date: 2005.11

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  91. Medaka Book

    International Symposium on Standardization of Medaka Bioresources 

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    Event date: 2005.11

    Language:English   Presentation type:Oral presentation (general)  

  92. メダカ突然変異体pcをモデルとした多発性嚢胞腎疾患の研究

    橋本寿史

    第35回日本腎臓学会西部学術大会 

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    Event date: 2005.9

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  93. ヒト多発性嚢胞腎疾患(PKD)モデルメダカpc突然変異体の原因遺伝子の同定

    橋本寿史、渡辺直樹、宮本理恵子、尾里建二郎、若松佑子

    第5回PKD研究会 

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    Event date: 2005.9

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  94. 左右軸形成に異常を示すメダカ突然変異体の解析

    吉田知也、渡辺直樹、橋本寿史、古谷-清木誠、若松佑子

    日本発生生物学会第38回大会 

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    Event date: 2005.6

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  95. ヒラメ・カレイにユニークな眼の左右性の形成機構

    鈴木徹、橋本寿史、有瀧真人

    日本発生生物学会第38回大会)、シンポジウム「さまざまな動物の器官形成における左右性創出メカニズム」 

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    Event date: 2005.6

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  96. ヒト多発性嚢胞腎疾患モデルメダカpc突然変異体の原因遺伝子の同定

    橋本寿史、宮本理恵子、渡辺直樹、久保優子、神藤智子、成田貴則、成瀬清、大石加寿子,野方恵子、新井理、小原雄治、武田洋幸、堀寛、若松佑子

    日本発生生物学会第38回大会 

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    Event date: 2005.6

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  97. メダカにおける前腎および中腎の発生過程

    宮本理恵子、スヴェトラーナ・フェドロバ、橋本寿史、若松佑子

    日本発生生物学会第38回大会 

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    Event date: 2005.6

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  98. Three-dimentional reconstruction of the adult kidney development and nephrogenesis in Oryzias latipes.

    CDB Symposium `Origin and Development of the Vertebrate Traits' 

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    Event date: 2005.4

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  99. Medaka pc mutant as a model of human polycystic kidney disease (PKD)

    The 9th research Forum on Progressive Renal Diseases 

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    Event date: 2005.2

    Language:English   Presentation type:Oral presentation (general)  

  100. Medaka pc mutant as a model of human polycystic kidney disease (PKD)

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    Event date: 2004.12

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  101. メダカ多発性嚢胞腎の表現型

    望月愛美子、原田智弘、松原礼奈、福田勝洋、橋本寿史、尾里建二郎、若松佑子

    日本発生生物学会第37回大会 

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    Event date: 2004.6

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  102. The medaka model of polycystic kidney disease

    The 8th research Forum on Progressive Renal Diseases 

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    Event date: 2004.2

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  103. メダカをモデルとした細胞分化制御機構の研究 Invited International conference

    橋本寿史、成瀬 清

    日本農芸化学会2018年度大会 シンポジウム「メダカ〜有用モデル生物としての産業応用への展開」  2018.3.18  人見清隆、橋本寿史

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    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    Venue:名古屋   Country:Japan  

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Research Project for Joint Research, Competitive Funding, etc. 9

  1. メダカをモデルとした色素斑形成の遺伝基盤に関する研究〜色素細胞におけるプロテインキナーゼAの活性制御メカニズム

    2018.4 - 2019.3

    研究助成 

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\1000000

  2. 魚類体細胞核移植における中心体の役割の解明

    2009.4

    豊秋奨学会 

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    Grant type:Competitive

  3. メダカ成体体細胞の新規核移植法における核移植個体形成機構の解析

    2008.4

    大幸財団 

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    Grant type:Competitive

  4. 核移植と染色体操作を組み合わせた新規手法による魚類体細胞クローンおよび遺伝子ターゲティング技術の開発

    2005.4 - 2009.3

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    Grant type:Competitive

    独自の体細胞核移植法により魚類では未だ実現されていない遺伝子ターゲティング技術を開発する。

  5. メダカをモデルとしたヒト遺伝性疾患の研究---多発性嚢胞腎疾患を中心とした分子遺伝学的研究

    2004.4 - 2005.3

    ノバルティス科学振興財団 

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    Grant type:Competitive

  6. メダカをモデルとしたヒト遺伝性疾患の研究---多発性嚢胞腎疾患を中心とした分子遺伝学的研究

    2004.4 - 2005.3

    上原記念生命科学財団 

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    Grant type:Competitive

  7. メダカをモデルとしたヒト遺伝病の研究-多発性嚢胞腎疾患原因遺伝子の同定

    2004.4 - 2005.3

    武田科学振興財団 

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    Grant type:Competitive

  8. 透明メダカを利用した腎臓の再生生物学に関する研究

    2004

    国内共同研究 

  9. メダカ突然変異体をモデルとした皮膚色素異常症の研究

    2002

    学内共同研究 

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KAKENHI (Grants-in-Aid for Scientific Research) 5

  1. Evolutionary genetic basis of developmental regulation of a novel cell type

    Grant number:20K06757  2020.4 - 2023.3

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    Authorship:Principal investigator 

    Grant amount:\4420000 ( Direct Cost: \3400000 、 Indirect Cost:\1020000 )

  2. Analysis of molecular mechanisms controlling fate choice of pigment cells

    Grant number:26440121  2014.4 - 2018.3

    Hashimoto Hisashi

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    Authorship:Principal investigator 

    Grant amount:\5200000 ( Direct Cost: \4000000 、 Indirect Cost:\1200000 )

    How individual cell fates become specified from multipotent progenitors is a fundamental question in developmental biology. Pigment cells derive from a multipotent progenitor, but while in zebrafish there are three types of pigment cells (melanocytes, iridophores and xanthophores), in medaka the progenitors form four (as zebrafish, plus leucophores), raising questions about how conserved mechanisms of fate specification of each pigment cell type are in these fish. To address them, we focus on Sox5 and Sox10, which we previously showed were involved in pigment cell development in medaka and zebrafish, respectively. We show that development of all pigment cells, except leucophores, is dependent on Sox10, and that Sox5 modulates Sox10 activity antagonistically in all pigment cells in zebrafish, and melanocytes and iridophores in medaka. In medaka, Sox5 acts cooperatively with Sox10 to promote xanthophore fate and to repress leucophore fate.

  3. 色素細胞をモデルとした細胞運命選択の分子メカニズムの解析

    2014.4 - 2017.3

    科学研究費補助金  基盤研究(C)

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    Authorship:Principal investigator 

  4. 色素細胞のサブタイプを生み出す分化制御機構の解明

    2011.4 - 2013.3

    科学研究費補助金  基盤研究(C)

    橋本寿史

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    Authorship:Principal investigator 

  5. 腎尿細管の形成と管径調節におけるメダカ多発性嚢胞腎原因遺伝子pcの役割

    2005

    科学研究費補助金  若手研究(B),課題番号:17770190

    橋本 寿史

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    Authorship:Principal investigator 

Industrial property rights 3

  1. 魚類胚の作製方法の改良

    若松佑子、橋本寿史、エカテリーナ・ブベンシコバ、エレナ・カフタノフスカヤ

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    Applicant:国立大学法人名古屋大学

    Application no:2007-241633  Date applied:2007.9

    Country of applicant:Domestic  

  2. 多発性嚢胞腎モデル小型魚類及びその利用

    橋本寿史、若松佑子、望月俊雄、宮本兼玄

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    Applicant:国立大学法人名古屋大学

    Application no:特願2007-198207  Date applied:2007.7

    Country of applicant:Domestic  

  3. 多発性嚢胞腎疾患関連遺伝子及びその利用

    橋本寿史,若松佑子

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    Applicant:国立大学法人名古屋大学

    Application no:PCT/JP2006/310862  Date applied:2005.4

    Country of applicant:Domestic  

 

Teaching Experience (Off-campus) 1

  1. 応用遺伝学

    2008.4 - 2013.3 中部大学)

 

Social Contribution 1

  1. メダカの色と遺伝

    Role(s):Appearance

    基礎生物学研究所  教育応援企画【みんなで観察しよう】メダカの産卵から孵化まで~基礎生物学研究所 ×niconico  2020.6

Academic Activities 6

  1. 平成30年度日本動物学会中部支部大会

    Role(s):Planning, management, etc.

    田中実  2018.12

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    Type:Academic society, research group, etc. 

  2. 第24回小型魚類研究会

    Role(s):Planning, management, etc.

    金森章  2018.8

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    Type:Academic society, research group, etc. 

  3. 日本農芸化学会2018年度大会

    Role(s):Planning, management, etc.

    人見清隆、橋本寿史  2018.3

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    Type:Competition, symposium, etc. 

  4. 第86回日本動物学会年会(2015年9月新潟開催) 第11回色素細胞シンポジウム「動物のからだを多様に彩るしくみ」

    Role(s):Planning, management, etc.

    橋本寿史、合田真  2015.9

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    Type:Competition, symposium, etc. 

  5. 第47回日本発生生物学会年会

    Role(s):Planning, management, etc.

    日比正彦  2014.5

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    Type:Competition, symposium, etc. 

  6. 医学・創薬に向けた小型魚類モデル利用推進ネットワーク

    Role(s):Planning, management, etc., Panel moderator, session chair, etc.

    公益財団法人 科学技術交流財団  2011 - 2012

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    Type:Academic society, research group, etc. 

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