Sox5 functions as a fate switch in medaka pigment cell development. Reviewed

Nagao Y, Suzuki T, Shimizu A, Kimura T, Seki R, Adachi T, Inoue C, Omae Y, Kamei Y, Hara I, Taniguchi Y, Naruse K, Wakamatsu Y, Kelsh RN, Hibi M, Hashimoto H

PLoS genetics   Vol. 10 ( 4 ) page： e1004246   2014.4

Dynein axonemal intermediate chain 2 is required for formation of the left-right body axis and kidney in medaka. Reviewed

Nagao Y, Cheng J, Kamura K, Seki R, Maeda A, Nihei D, Koshida S, Wakamatsu Y, Fujimoto T, Hibi M, Hashimoto H.

Developmental Biology   Vol. 347   page： 53-61   2010

Kidney regeneration through nephron neogenesis in medaka. Reviewed

Watanabe, N., Kato, M., Suzuki, N., Inoue, C., Fedorova, S., Hashimoto, H., Maruyama, S., Matsuo, S., and Wakamatsu, Y.

Development Growth & Differentitation   Vol. 51   page： 135-143   2009

A murine model of neonatal diabetes mellitus in Glis3-deficient mice. Reviewed

Watanabe, N., Hiramatsu, K., Miyamoto, R., Yasuda, K., Suzuki, N., Oshima, N., Kiyonari, H., Shiba, D., Nishio, S., Mochizuki, T., Yokoyama, T., Maruyama, S., Matsuo, S., Wakamatsu, Y., and Hashimoto, H.

FEBS Letters   Vol. 583   page： 2108-2113   2009

Polycystic kidney disease in the medaka (Oryzias latipes) pc mutant caused by a mutation in the Gli-similar3 (glis3) gene. Reviewed

Hashimoto, H., Miyamoto, R., Watanabe, N., Shiba, D., Ozato, K., Inoue, C., Kubo, Y., Koga, A., Jindo, T., Narita, T., Naruse, K., Ohishi, K., Nogata, K., Shin-I, T., Asakawa, S., Shimizu, N., Miyamoto, T., Mochizuki, T., Yokoyama, T., Hori, H., Takeda, H., Kohara, Y., and Wakamatsu, Y.

PLoS ONE   Vol. 4 ( 7 ) page： e6299   2009

Renal glomerulogenesis in medaka fish, Oryzias latipes. Reviewed

Fedorova, S., Miyamoto, R., Harada, T., Isogai, S., Hashimoto, H., Ozato, K., and Wakamatsu, Y.

Developmental Dynamics   Vol. 237   page： 2342-2352   2008

The Cerberus/Dan-family protein Charon is a negative regulator of Nodal signaling during left-right patterning in zebrafish Reviewed

H. Hashimoto, M. Rebagliati, N. Ahmad, O. Muraoka, T. Kurokawa, M. Hibi, and T. Suzuki

Development   Vol. 131   page： 1741-1753   2004

Isolation and characterization of a Japanese flounder clonal line, reversed, which exhibits reversal metamorphic left-right asymmetry. Reviewed

Hashimoto, H., Mizuta, A., Okada, N., Suzuki, T., Tagawa, M., Tabata, K., Yokoyama, Y., Sakaguchi, M., Tanaka, M., and Toyohara, H.

Mechanisms of Development   Vol. 111   page： 17-24   2002

Biochemical characterization of medaka (Oryzias latipes) fibrinogen gamma and its gene disruption resulting in anemia as a model fish

Meng Qi, Watanabe Yuko, Tatsukawa Hideki, Hashimoto Hisashi, Hitomi Kiyotaka

JOURNAL OF BIOCHEMISTRY     2022.8

A point-mutation in the C-domain of CMP-sialic acid synthetase leads to lethality of medaka due to protein insolubility Reviewed

Wu Di, Arakawa Hiromu, Fujita Akiko, Hashimoto Hisashi, Hibi Masahiko, Naruse Kiyoshi, Kamei Yasuhiro, Sato Chihiro, Kitajima Ken

SCIENTIFIC REPORTS   Vol. 11 ( 1 )   2021.12

Thrombin-deficient mutant of medaka, a model fish, displays serious retardation in blood coagulation Reviewed

Watanabe Yuko, Oguri Rina, Suzuki Risa, Meng Qi, Ishikawa Yuta, Tatsukawa Hideki, Hashimoto Hisashi, Hitomi Kiyotaka

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY   Vol. 85 ( 4 ) page： 824 - 833   2021.3

Identification and Characterization of Highly Fluorescent Pigment Cells in Embryos of the Arabian Killifish (Aphanius Dispar) Reviewed International coauthorship

Hamied Atyaf, Alnedawy Qusay, Correia Ana, Hacker Christian, Ramsdale Mark, Hashimoto Hisashi, Kudoh Tetsuhiro

ISCIENCE   Vol. 23 ( 11 )   2020.11

Gene disruption of medaka (Oryzias latipes) orthologue for mammalian tissue-type transglutaminase (TG2) causes movement retardation Reviewed

Watanabe Yuko, Okuya Kazuho, Takada Yuki, Kinoshita Masato, Yokoi Saori, Chisada Shinichi, Kamei Yasuhiro, Tatsukawa Hideki, Yamamoto Naoyuki, Abe Hideki, Hashimoto Hisashi, Hitomi Kiyotaka

JOURNAL OF BIOCHEMISTRY   Vol. 168 ( 3 ) page： 213 - 222   2020.9

Highly efficient generation of knock-in transgenic medaka by CRISPR/Cas9-mediated genome engineering Reviewed

Watakabe Ikuko, Hashimoto Hisashi, Kimura Yukiko, Yokoi Saori, Naruse Kiyoshi, Higashijima Shin-ichi

ZOOLOGICAL LETTERS   Vol. 4   2018.2

Sox5 is involved in germ-cell regulation and sex determination in medaka following co-option of nested transposable elements. Reviewed International coauthorship

Schartl M, Schories S, Wakamatsu Y, Nagao Y, Hashimoto H, Bertin C, Mourot B, Schmidt C, Wilhelm D, Centanin L, Guiguen Y, Herpin A.

BMC Biology   Vol. 16   page： 16   2018.1

Axis Formation and Its Evolution in Ray-Finned Fish

Hibi Masahiko, Takeuchi Masaki, Hashimoto Hisashi, Shimizu Takashi

REPRODUCTIVE AND DEVELOPMENTAL STRATEGIES: THE CONTINUITY OF LIFE     page： 709 - +   2018

Higher susceptibility to osmolality of the medaka (Oryzias latipes) mutants in orthologue genes of mammalian skin transglutaminases

Watanabe Yuko, Furukawa Eri, Tatsukawa Hideki, Hashimoto Hisashi, Kamei Yasuhiro, Taniguchi Yoshihito, Hitomi Kiyotaka

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY   Vol. 82 ( 7 ) page： 1165 - 1168   2018

Biochemical characterization of a medaka (Oryzias latipes) orthologue for mammalian Factor XIII and establishment of a gene-edited mutant Reviewed

FEBS JOURNAL   Vol. 284 ( 17 ) page： 2843 - 2855   2017.9

Medaka and zebrafish contactin1 mutants as a model for understanding neural circuits for motor coordination

Takeuchi Miki, Inoue Chikako, Goshima Akiko, Nagao Yusuke, Shimizu Koichi, Miyamoto Hiroki, Shimizu Takashi, Hashimoto Hisashi, Yonemura Shigenobu, Kawahara Atsuo, Hirata Yutaka, Yoshida Masayuki, Hibi Masahiko

GENES TO CELLS   Vol. 22 ( 8 ) page： 723 - 741   2017.8

Biochemical characterization of the medaka (Oryzias latipes) orthologue for mammalian tissue-type transglutaminase (TG2)

Takada Yuki, Watanabe Yuko, Okuya Kazuho, Tatsukawa Hideki, Hashimoto Hisashi, Hitomi Kiyotaka

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY   Vol. 81 ( 3 ) page： 469 - 474   2017.3

Osteocrin, a peptide secreted from the heart and other tissues, contributes to cranial osteogenesis and chondrogenesis in zebrafish Reviewed

Chiba Ayano, Watanabe-Takano Haruko, Terai Kenta, Fukui Hajime, Miyazaki Takahiro, Uemura Mami, Hashimoto Hisashi, Hibi Masahiko, Fukuhara Shigetomo, Mochizuki Naoki

DEVELOPMENT   Vol. 144 ( 2 ) page： 334 - 344   2017.1

Medaka and zebrafish contactin1 mutants as a model for understanding neural circuits for motor coordination.

Takeuchi M, Inoue C, Goshima A, Nagao Y, Shimizu K, Miyamoto H, Shimizu T, Hashimoto H, Yonemura S, Kawahara A, Hirata Y, Yoshida M, Hibi M.

Genes to Cells   Vol. 22   page： 723-741   2017

Biochemical characterization of a medaka (Oryzias latipes) orthologue for mammalian Factor XIII and establishment of a gene-edited mutant.

Horimizu R, Ogawa R, Watanabe Y, Tatsukawa H, Kinoshita M, Hashimoto H, Hitomi K.

FEBS Journal   Vol. 284   page： 2843-2855   2017

Osteocrin, a peptide secreted from the heart and other tissues, contributes to cranial osteogenesis and chondrogenesis in zebrafish. Reviewed

Chiba A, Watanabe-Takano H, Terai K, Fukui H, Miyazaki T, Uemura M, Hashimoto H, Hibi M, Fukuhara S, Mochizuki N.

Developmen   Vol. 144   page： 334-344   2017

Biochemical characterization of the medaka (Oryzias latipes) orthologue for mammalian tissue-type transglutaminase (TG2). Reviewed

Takada Y, Watanabe Y, Okuya K, Tatsukawa H, Hashimoto H, Hitomi K.

Bioscience, Biotechnology, and Biochemistry   Vol. 81   page： 469-474   2017

Establishment of oct4:egfp transgenic and oct4:egfp /beta-actin:DsRed double transgenic medaka lines. Reviewed

Yokota S, Matsuno R, Kato H, Hashimoto H, Kinoshita M, Yokoi H, Suzuki T.

In Vitro Cellular and Developmental Biology-Animal   Vol. 52 ( 6 ) page： 646-653   2016

Biochemical characterization of medaka (Oryzias latipes) transglutaminases, OlTGK1 and OlTGK2, as Orthologues of human keratinocyte-type transglutaminase. Reviewed

Kikuta A, Furukawa E, Ogawa R, Suganuma N, Saitoh M, Nishimaki T, Katsumura T, Oota H, Kawamoto T, Tatsukawa H, Hashimoto H, Hitomi K.

PLoS ONE   Vol. 10 ( 12 ) page： e0144194   2015

Multiple pigment cell types contribute to the black, blue, and orange ornaments of male guppies (Poecilia reticulata). Reviewed

Kottler VA, Koch I, Flötenmeyer M, Hashimoto H, Weigel D, Dreyer C.

PLoS ONE   Vol. 9 ( 1 ) page： e85647   2014.1

A protocol for adult somatic cell nuclear transfer in medaka fish (Oryzias latipes) with a high rate of viable clone formation. Reviewed

Bubenshchikova E, Kaftanovskaya E, Adachi T, Hashimoto H, Kinoshita M, Wakamatsu Y.

Cellular Reprogramming     2014

Taking striping up a notch. Invited Reviewed

Goda M, Kelsh RN, Hashimoto H

Pigment Cell and Melanoma Research   Vol. 27   page： 688-689   2014

The Medaka zic1/zic4 Mutant Provides Molecular Insights into Teleost Caudal Fin Evolution Reviewed

Moriyama Y, Kawanishi T, Nakamura R, Tsukahara T, Sumiyama K, Suster ML, Kawakami K, Toyoda A, Fujiyama A, Yasuoka Y, Nagao Y, Sawatari E, Shimizu A, Wakamatsu Y, Hibi M, Taira M, Okabe M, Naruse K, Hashimoto H, Shimada A, Takeda H

Current Biology   Vol. 22   page： 601-607   2012

Derlin-1 and UBXD8 are engaged in dislocation and degradation of lapidated ApoB-100 at lipid droplets. Reviewed

Suzuki M, Otsuka T, Ohsaki Y, Cheng J, Taniguchi T, Hashimoto H, Taniguchi H, Fujimoto T.

Molecular Biology of the Cell   Vol. 23   page： 800-810   2012

Nuclear transfer of embryonic cell nuclei to non-enucleated eggs in zebrafish, Danio rerio. Invited Reviewed

Hattori M, Hashimoto H, Bubenshchikova E, Wakamatsu Y.

International Journal of Biological Sciences   Vol. 7 ( 4 ) page： 460-468   2011.4

Detection of vitellogenin incorporation into zebrafish oocytes by FITC fluorescence. Reviewed

Matsuda Y, Ito Y, Hashimoto H, Yokoi H, Suzuki T.

Reproductive Biology and Endocrinology   Vol. 9   page： 45   2011

Embryogenic staging of fugu, Takifugu rubripes, and expression profiles of aldh1a2 and aldh1a3. Reviewed

Uji S, Kurokawa T, Hashimoto H, Kasuya T, Suzuki T.

Development, Growth and Differentiation   Vol. 53   page： 715-725   2011

Metamorphic pitx2 expression in the left habenula correlated with lateralization of eye-sidedness in flounder Reviewed

Suzuki, T., Washio,Y., Aritaki, M., Fujinami, Y., Shimizu, D., Uji, S., and Hashimoto, H.

Development, Growth & Differentiation   Vol. 51 ( 9 ) page： 797-808   2009.12

Cell growth promoting activity of fluid from eye sacs of bubble-eye goldfish (Carassius auratus). Reviewed

Sawatari, E., Hashimoto, H., Matsumura, T., Iwata, Y., Yamamoto, N., Yokoyama, Y., and Wakamatsu, Y.

Zoological Science   Vol. 26   page： 254-258   2009

Overexpression of the dominant-negative form of myostatin results in doubling of muscle-fiber number in transgenic medaka (Oryzias latipes). Reviewed

Sawatari, E., Seki, R., Adachi, T., Hashimoto, H., Uji, S., Wakamatsu, Y., Nakata, T., and Kinoshita, M.

Comp Biochem Physiol A Mol Integr Physiol   Vol. 155   page： 183-189   2009

Nuclear transplants from adult somatic cells generated by a novel method using diploidized eggs as recipients in medaka fish (Oryzias latipes). Reviewed

Cloning and Stem Cells   Vol. 10   page： 443-452   2008

Embryogenesis and expression profile of charon and nodal-pathway genes in sinistral (Paralichthys olivaceus) and dextral (Verasper variegatus) flounders. Reviewed

Hashimoto, H., Aritaki, M., Uozumi, K., Uji, S., Kurokawa, T., and Suzuki, T.

Zoological Science   Vol. 24   page： 137-146   2007

Diploidized eggs reprogram adult somatic cell nuclei to pluripotency in nuclear transfer in medaka fish (Oryzias latipes). Reviewed

Bubenshchikova, E., Kaftanovskaya, E., Motosugi, N., Fujimoto, T., Arai, K., Kinoshita, M., Hashimoto, H., Ozato K., and Wakamatsu, Y.

Development Growth & Differentiation   Vol. 49 ( 9 ) page： 699-709   2007

左ヒラメに右カレイの謎に迫る Invited

鈴木徹，有瀧真人，宇治督，橋本寿史

化学と生物   Vol. 45   page： 511-515   2007

Flounder and fugu have a single lefty gene that covers the functions of lefty1 and lefty2 of zebrafish during L-R patterning. Reviewed

Hashimoto, H., Uji, S., Kurokawa, T., Washio., Y., and Suzuki, T.

Gene   Vol. 387   page： 126-132   2007

cDNA cloning of Japanese oyster stress protein homologous to the mammalian 78-kDa glucose regulated protein and its induction by heatshock. Reviewed

Yokoyama, Y., Hashimoto, H., Kubota, S., Kuriyama, A., Ogura, Y., Mizuta, S., Yoshinaka, R., and Toyohara, H.

Fisheries Science   Vol. 72   page： 402-409   2006

Fish mesonephric model of polycystic kidney disease in medaka (Oryzias latipes) pc mutant Reviewed

E. Mochizuki, K. Fukuta, T. Tada, T. Harada, N. Watanabe, S. Matsuo, H. Hashimoto, K. Ozato, and Y. Wakamatsu

Kidney International   Vol. 68   page： 23-34   2005

ヒラメ・カレイの体の左右非対称性と内臓・脳の左右非対称性形成との関わり Invited

鈴木徹、橋本寿史、有瀧真人、宇治督、黒川忠英

日本動物育種学会誌   Vol. 33   page： 55-65   2005

Expression of HSP70 in response to heat-shock and its cDNA cloning from Mediterranean blue mussel. Reviewed

Toyohara, H., Hosoi, M., Hayashi, I., Kubota, S., Hashimoto, H., and Yokoyama, Y.

Fisheries Science   Vol. 71   page： 327-332   2005

Zinc finger protein too few controls the development of monoaminergic neurons Reviewed

G. Levkowitz, J. Zeller, H. I. Sirotkin, D. French, S. Schilbach, H. Hashimoto, M. Hibi, W. S. Talbot, and A. Rosenthal

Nature Neuroscience   Vol. 6   page： 28-33   2003

Identification of gastrin and multiple cholecystokinin genes in teleost. Reviewed

Kurokawa, T., Suzuki, T., and Hashimoto, H.

Peptides   Vol. 24   page： 227-235   2003

Differentiation of chondrocytes and scleroblasts during dorsal fin skeletogenesis in flounder larvae. Reviewed

Suzuki, T., Haga, Y., Takeuchi, T., Uji, S., Hashimoto, H., and Kurokawa, T.

Development Growth & Differentiation   Vol. 45   page： 435-448   2003

cDNA sequence and tissue expression of Fugu rubripes prion protein-like: a candidate for the teleost orthologue of tetrapod PrPs. Reviewed

Suzuki, T., Kurokawa, T., Hashimoto, H., and Sugiyama, M.

Biochemical and Biophysical Research Communications   Vol. 294   page： 912-917   2002

The nuclear export signal (NES) found in the amino-terminal region of carp MEK1 and MKK6 is lacking in carp MKK4. Reviewed

Hashimoto, H., Matsuo, Y., Yokoyama, Y., Toyohara, H., and Sakaguchi, M.

Biochim. Biophys. Acta   Vol. 1575   page： 139-142   2002

脊椎動物初期体軸形成の分子機構―ゼブラフィッシュからの知見 Invited

日比正彦，清水貴史，橋本寿史，柳成林，山中庸次郎，平野俊夫

小型魚類研究の新展開　（蛋白質核酸酵素増刊）   Vol. 45   page： 2720-2731   2000

Zebrafish Dkk1 functions in forebrain specification and axial mesendoderm formation Reviewed

H. Hashimoto, M. Ito, Y. Yamanaka, S. Yamashita, T. Shimizu, L. Solnica-Krezel, M. Hibi, and T. Hirano

Developmental Biology   Vol. 217   page： 138-152   2000

Cooperative roles of Bozozok/Dharma and Nodal-related proteins in the formation of the dorsal organizer in zebrafish Reviewed

T. Shimizu, Y. Yamanaka, S. Ryu, H. Hashimoto, T. Yabe, T. Hirata, Y. Bae, M. Hibi, and T. Hirano

Mechanisms of Development   Vol. 91   page： 293-303   2000

Identification of a nuclear export signal in MKK6, an activator of the carp p38 mitogen-activated protein kinases Reviewed

H. Hashimoto, M. Fukuda, Y. Matsuo, Y. Yokoyama, E. Nishida, H. Toyohara, and M. Sakaguchi

European Journal of Biochemistry   Vol. 267   page： 4362-4371   2000

Fezl: a novel zinc finger gene expressed in zebrafish forebrain Reviewed

H. Hashimoto, T. Yabe, T. Hirata, T. Shimizu, Y. Bae, Y. Yamanaka, M. Hibi, and T. Hirano

Mechanisms of Development   Vol. 97   page： 191-195   2000

Suppression of apoptosis of fish cells by acclimatization to hypertonicity Reviewed

H. Hashimoto, Y. Matsuo, K. Takeuchi, Y. Yokoyama, H. Toyohara, and M. Sakaguchi

Fisheries Science   Vol. 65   page： 145-149   1999

cDNA cloning of heat-inducible HSP70, a 70.6kDa heat shock protein, in Japanese Flounder Paralichtys olivaceus Reviewed

Y. Yokoyama, H. Hashimoto, S. Kubota, M. Kinoshita, H. Toyohara, M. Sakaguchi, M. Tanaka, T. Seikai, and M. Kanamori

Fisheries Science   Vol. 64   page： 964-968   1998

Cell growth of fish cultures in hyper- and hypoosmotic media Reviewed

H. Hashimoto, K. Takeuchi, Y. Matsuo, Y. Yokoyama, H. Toyohara, and M. Sakaguchi

Fisheries Science   Vol. 64   page： 350-35   1998

Existence of two isoforms of extracellular-signal regulated kinase in fish Reviewed

H. Hashimoto, Y. Yokoyama, Y. Matsuo, H. Toyohara, M. Kohno, and M. Sakaguchi

Journal of Biochemistry   Vol. 123   page： 1031-1035   1998

Induction of apoptosis in fish cells by hypertonic stress Reviewed

H. Hashimoto, Y. Matsuo, Y. Yokoyama, H. Toyohara, and M. Sakaguchi

Fisheries Science   Vol. 64   page： 820-825   1998

Comlementary DNA cloning of HSC71, a 71 kDa heat-shock cognate protein, in Japanese Flounder Paralichtys olivaceus Reviewed

Y. Yokoyama, H. Hashimoto, S. Kubota, M. Kinoshita, H. Toyohara, M. Sakaguchi, and M. Kanamori

Fisheries Science   Vol. 64   page： 388-392   1998

Structure and expression of carp mitogen-activated protein kinases homologous to mammalian JNK/SAPK Reviewed

H. Hashimoto, Y. Matsuo, Y. Yokoyama, H. Toyohara, and M. Sakaguchi

Journal of Biochemistry   Vol. 122   page： 381-386   1997

Effects of carp (Cyprinus carpio L.) serum on the growth of goldfish (Carassius auratus L.) fin cells in early passage Reviewed

H. Hashimoto, H. Toyohara, Y. Yokoyama, M. Sakaguchi, K. Ozato, and Y. Wakamatsu

Journal of Fish Biology   Vol. 50   page： 201-207   1997

Molecular cloning and growth hormone-regulated gene expression of carp insulin-like growth factor-I Reviewed

H. Hashimoto, S. Mikawa, E. Takayama, Y. Yokoyama, H. Toyohara, and M. Sakaguchi

Biochemistry and Molecular Biology International   Vol. 41   page： 877-886   1997

Transgenic expression of L-gulono--lactone oxidase in medaka (Oryzias latipes), a teleost fish that lacks this enzyme necessary for L-ascorbic acid biosythesis Reviewed

H. Toyohara, T. Nakata, K. Touhata, H. Hashimoto, M. Kinoshita, M. Sakaguchi, M. Nishikimi, K. Yagi, Y. Wakamatsu, and K. Ozato

Biochemical and Biophysical Research Communications   Vol. 223   page： 650-653   1996

Generation of germ-line chimeras in medaka (Oryzias latipes) Reviewed

Y. Wakamatsu, K. Ozato, H. Hashimoto, M. Kinoshita, M. Sakaguchi, T. Iwamatsu, Y. Hyodo-Taguchi, and H. Tomita

Molecular Marine Biology and Biotechnology   Vol. 2   page： 325-332   1993

魚類発生学の基礎

清水貴史、橋本寿史、日比正彦（ Role： Joint author ,  第６章　中胚葉誘導）

恒星社厚生閣  2018.9  （ ISBN:9784769914853 ）

めだかの学校　山本時男博士と日本のメダカ研究　宗宮弘明、足立 守、野崎ますみ、成瀬 清編

橋本寿史（ Role： Contributor ,  第II部　メダカ研究の最近　第２章　メダカの色について考える）

あるむ  2018.1  （ ISBN:978-4-86333-133-4 ）

Kidney development, regeneration and polycystic kidney disease in medaka in Medaka: model for organogenesis, human disease and evolution (ed. Naruse K, Tanaka M, Takeda H.)

Hisashi Hashimoto（ Role： Joint author）

Springer  2011  （ ISBN:978-4-431-92690-0 ）

Regenerative Nephrology

Goligorsky MS.（ Role： Joint author）

Academic Press  2010 

Medaka: Biology, Management, and Experimental Protocols ed. Kinoshita, M., Murata, K., Naruse, K. and Tanaka, M.

Hisashi Hashimoto（ Role： Sole author ,  Strain preservation and related techniques）

Blackwell  2008 

Medaka: Biology, Management, and Experimental Protocols ed. Kinoshita, M., Murata, K., Naruse, K. and Tanaka, M.

Hisashi Hashimoto（ Role： Sole author ,  Looking at adult medaka: kidney）

Blackwell  2008 

Medaka: Biology, Management, and Experimental Protocols ed. Kinoshita, M., Murata, K., Naruse, K. and Tanaka, M.

Hisashi Hashimoto（ Role： Sole author ,  Looking at adult medaka: see-through medaka）

Blackwell  2008 

Medaka: Biology, Management, and Experimental Protocols ed. Kinoshita, M., Murata, K., Naruse, K. and Tanaka, M.

Hashimoto H, Bubenshchikova E, Kaftanovskaya E, Wakamatsu YHisashi Hashimoto（ Role： Joint author ,  Advanced techniques: nuclear transplantation）

Blackwell  2008 

Medaka: Biology, Management, and Experimental Protocols ed. Kinoshita, M., Murata, K., Naruse, K. and Tanaka, M.

Hisashi Hashimoto（ Role： Sole author ,  Looking at medaka embryos: kidney）

Blackwell  2008 

*泳ぐDNA

猿渡敏郎編（ Role： Joint author）

東海大学出版会  2007.12 

Hypothesis for variegated body pigmentation based on aberrant regulation of PKA activity. International coauthorship

Goda M, Wakamatsu Y, Kobayashi K, Inoue C, Villareal M, Isoda, H, Ohtani K, Nishimaki T, Oota H, Ogawa M, Kimura T, Naruse K, Kelsh RN, Hibi M, Hashimoto H

Biochemical phenotypes of the knockout medaka for the α2,6-sialyltransefrases I and II genes

Omoto T, Wu D, Hashimoto H, Hibi M, Hane M, Sato C, Kitajima K

Roles of Sox9b in medaka pigment cell development

Tunogai, Y., Hibi, M., Hashimoto, H.

第５３回日本発生生物学会大会 

Pax3b and Pax7a have sequential function to regulate fate choice of pigment cells in medaka

Hashimoto H, Watakabe I, Miyadai M, Takada H, Kimura T, Naruse K, Higashijima S, Hibi M

第５３回日本発生生物学会大会  2019.5 

メダカ黒斑変異体Variegatedはヒトカーニー複合の皮膚病態モデルである

橋本 寿史、合田 真、静 隆志、小林 健一、三木 千晶、井上 慎子、Villareal Myra、礒田 博子、大谷 勝己、西槇 俊之、木村 哲晃、成瀬 清、日比正彦

第９０回日本動物学会  2019.9 

Pax3 and Pax7 sequentially regulate fate choice of pigment cells in medaka and zebrafish International coauthorship

Miyadai M, Takada H, Kimura T, Tsunogai Y, Kelsh R, Naruse K, Hibi M, Hashimoto H

2019.5 

HMG型転写因子Sox9bはSox10と協調してメダカの色素胞発生を促進する

橋本 寿史、宮台 元裕、日比 正彦

平成３１年度日本動物学会中部支部大会  2018.12 

メダカとゼブラフィッシュの比較発生学研究〜色素細胞の発生における運命決定メカニズム Invited

橋本寿史、成瀬清

第４１回日本分子生物学会ワークショップ「生物種横断的研究の進展とバイオリソースの役割」  2018.11.28 

bHLH型転写制御因子MitfおよびTfecはメダカの黒色素細胞の発生を冗長的に促進する International coauthorship International conference

橋本 寿史、木村 哲晃、宮台 元裕、長尾 勇佑、ロバート ケルシュ、成瀬 清、日比 正彦

第８９回日本動物学会年会  2018.9 

Pax3 and Pax7 differentially regulate fate choice of pigment cells in zebrafish and medaka International coauthorship

Miyadai M, Takada H, Kimura T, Kelsh RN, Naruse K, Hibi M, Hashimoto H

2018.8.25 

Mitf and Tfec transcription factors redundantly function in melanocyte development in medaka International coauthorship

Hashimoto H, Kimura T, Miyadai M, Nagao Y, Kelsh RN, Naruse K, Hibi M

2018.8.25 

Redundant functions of Mitf/Tfec family transcription factors regulate melanocyte development in medaka International coauthorship

Hashimoto H, Kimura T, Miyadai M, Nagao Y, Kelsh RN, Naruse K, Hibi M

Pax3とPax7は色素細胞の運命決定を制御する

宮台元裕、髙田広之、木村哲晃、成瀬 清、ロバートケルシュ、日比正彦、橋本寿史

第８８回日本動物学会年会 

Pax3 and Pax7 differentially regulate fate choice of pigment cells in zebrafish. International conference

Miyadai M, Takada H, Kelsh R, Hibi M, Hashimoto H

Sox5 modulates Sox10 function in pigment cell fate specification in medaka and zebrafish. International coauthorship International conference

Nagao Y, Takada H, Miyadai M, Seki R, Kamei Y, Hara I, Taniguchi Y, Naruse K, Hibi M, Kelsh R, Hashimoto H

A variegated medaka mutant Va: a model of human Carney complex. International coauthorship

Goda M, Shizuka T, Inoue C, Nishikawa K, Miki C, Kimura T, Villareal MO, Isoda H, Naruse K, Hibi M, Wakamatsu Y, Hashimoto H

Sox5 modulates Sox10-meiated pigment cell fate specification in medaka and zebrafish. International coauthorship International conference

Nagao Y, Takada H, Miyadai M, Seki R, Kamei Y, Hara I, Taniguchi Y, Naruse K, Hibi M, Kelsh RN, Hashimoto H

モデル生物としてメダカを用いたタンパク質架橋化酵素の生理的機能解析 International conference

堀水里麻、小河亮太、橋本寿史、木下政人、辰川英樹、人見清隆

第３８回日本分子生物学会年会・第８８回日本生化学会大会合同大会 

Generation of zebrafish sox5 mutant by CRISPR for understanding the mechanism of fate specification of pigment cells in teleost.

Takada H, Nagao Y, Adachi T, Hibi M, Kelsh RN, Hashimoto H.

Generation of zebrafish sox5 mutant by CRISPR for understanding the mechanism of fate specification of pigment cells in teleost.

Takada H, Nagao Y, Adachi T, Hibi M, Kelsh RN, Hashimoto H

モデル生物としてメダカのタンパク質架橋化酵素ファミリーとその機能に関する解析

高田佑紀、奥谷冬穂、木下政人、橋本寿史、辰川英樹、人見清隆

日本農芸化学会中部支部例会 

Roles of sox10 and its possible interaction with sox5 in pigment cell development. International conference

Nagao Y, Takada H, Seki R, Kamei Y, Hara I, Taniguchi Y, Naruse K, Hibi M, Kelsh RN, Hashimoto H.

European Society for Pigment Cell Research 

Roles of Sox10 and its possible interaction with Sox5 in pigment cell development. International conference

Nagao Y, Takada H, Seki R, Kamei Y, Hara I, Taniguchi Y, Naruse K, Hibi M, Kelsh RN, Hashimoto H.

7th European Zebrafish Meeting 

Generation of zebrafish sox5 mutant by CRISPR for understanding the mechanism of fate specification of pigment cells in teleost. International conference

Takada H, Nagao Y, Adachi T, Hibi M, Kelsh RN, Hashimoto H

7th European Zebrafish Meeting 

Roles of sox10 and its possible interaction with sox5 in pigment cell development of medaka.

Nagao Y, Takada H, Seki R, Kamei Y, Hara I, Kimura T, Taniguchi Y, Naruse K, Kelsh RN, Hibi M, Hashimoto H.

Roles of sox10 and its genetic interaction with sox5 in pigment cell development.

Nagao Y, Takada H, Seki R, Kamei Y, Hara I, Kimura T, Taniguchi Y, Naruse K, Kelsh RN, Hibi M, Hashimoto H.

Sox5 controls a fate choice during pigment cell development in medaka.

Nagao Y, Adachi T, Shimizu A, Seki R, Inoue C, Kamei Y, Hara I, Kimura T, Taniguchi Y, Naruse K, Kelsh RN, Wakamatsu Y, Hibi M, Hashimoto H

Sox5 functions as a fate switch in medaka pigment cell development. International conference

Hashimoto H

2nd Strategical Meeting for Medaka Research 

色素細胞をモデルとした細胞運命決定機構の解析

橋本 寿史

基礎生物学研究所重点共同利用研究シンポジウム「メダカを使った解析パイプライン〜ヒト疾患モデルとしてのメダカ：コンディショナルKOなどを使った多面的解析系の確立〜」 

メダカ色素細胞分化におけるSox5の役割

長尾勇佑、橋本寿史

第８４回日本動物学会年会、第９回色素細胞シンポジウム「お魚大会」 

Sox5 is involved in fate specification of pigment cells in medaka.

Nagao Y, Adachi T, Shimizu A, Seki R, Inoue C, Kamei Y, Hara I, Kimura T, Taniguchi Y, Naruse K, Kelsh RN, Wakamatsu Y, Hibi M, Hashimoto H

Sox5 is involved in fate specification of pigment cells in medaka.

メダカSox5は色素細胞の運命決定に関与する

長尾勇佑、足立朋子、清水厚志、関 良子、井上慎子、亀井保博、原 郁代、木村哲晃、谷口善仁、成瀬 清、ロバート・ケルシュ、若松佑子、日比正彦、橋本寿史

第３５回日本分子生物学会年会 

Sox5 is involved in fate specification of pigment cells in medaka.

Nagao Y, Adachi T, Shimizu A, Seki R, Inoue C, Kamei Y, Hara I, Taniguchi Y, Naruse K, Kelsh RN, Wakamatsu Y, Hibi M, Hashimoto H.

細胞表面α2,6-結合シアル酸残基はメダカ初期発生の進行に必要である

丸山恵美、田嶋克枝、ラニィ・チャン、足立朋子、橋本寿史、日比正彦、佐藤ちひろ、北島 健

第８３回日本動物学会年会 

Sox5 regulates the development of neural crest-derived pigment cells in medaka and zebrafish. International conference

Adachi T, Nagao Y, Chau V, Hibi M, Kelsh RN, Hashimoto H.

The 17th Meeting of the European Society for Pigment Cell Research 

Sox5 is involved in fate specification of pigment cell in medaka. International conference

Nagao, Y., Adachi, T., Shimizu, A. Seki, R., Inoue, C., Kamei, Y., Hara, I., Taniguchi, Y., Naruse, K., Kelsh, R.N., Wakamatsu, Y., Hibi, M., and Hashimoto, H.

10th International Conference on Zebrafish Development and Genetics 

Sox5 is involved in fate specification of pigment cells in medaka.

Nagao Y, Adachi T, Shimizu A, Seki R, Inoue C, Kamei Y, Hara I, Taniguchi Y, Naruse K, Kelsh RN, Wakamatsu Y, Hibi M, Hashimoto H.

Sox5 controls pigment cell development from the neural crest. International conference

Adachi T, Nagao Y, Chau V, Hibi M, Kelsh RN, Hashimoto H

British Society for Developmental Biology, British Society for Cell Biology and Japanese Society of Developmental Biologists Joint Spring Meeting 

Pigment specification in medaka.

Hashimoto H, Adachi T, Nagao Y, Kelsh RN, Hibi M.

GCOE International Symposium- Formation and Function of Brain Networks: From Genes to Behavior. 

Roles of a SoxD gene sox5 and its genetic interaction with SoxE genes in pigment cell development in medaka.

Nagao Y, Adachi T, Shimizu A, Seki R, Inoue C, Kamei Y, Hara I, Taniguchi Y, Naruse K, Kelsh NR, Wakamatsu Y, Hibi M, Hashimoto H.

GCOE International Symposium- Formation and Function of Brain Networks: From Genes to Behavior. 

Visualization of oct3/4-expression cells during medaka organ regeneration.

Hashimoto H, Adachi T, Seki R, Sawatari E, Hibi M, Suzuki T

Sox5 is involved in fate specification of pigment cell in medaka.

Nagao Y, Adachi T, Shimizu A, Seki R, Inoue C, Kamei Y, Hara I, Taniguchi Y, Naruse K, Kelsh NR, Wakamatsu Y, Hibi M, Hashimoto H

Roles of a SoxD gene sox5 and its genetic interaction with SoxE genes in pigment cell development. International conference

Nagao Y, Adachi T, Shimizu A, Seki R, Inoue C, Kamei Y, Hara I, Taniguchi Y, Naruse K, Kelsh NR, Wakamatsu Y, Hibi M, Hashimoto H.

National BioResource Project-Media- The1st Strategic Meeting for Medaka Research 

白色素胞を異所的に過形成するメダカ変異体ml-3

長尾勇佑、足立朋子、清水厚志、関 良子、井上慎子、亀井保博、原 郁代、谷口善仁、成瀬 清、ロバート・ケルシュ、若松佑子、日比正彦、橋本寿史

第８２回日本動物学会 

メダカ初期発生におけるシアロ糖鎖の重要性の検証

丸山恵実、足立朋子、橋本寿史、日比正彦、佐藤ちひろ、北島 健

第８２回日本動物学会 

Roles of a SoxD gene sox5 and its genetic interaction with SoxE genes in pigment cell development

Nagao Y, Adachi T, Shimizu A, Seki R, Inoue C, Kamei Y, Hara I, Taniguchi Y, Naruse K, Kelsh NR, Wakamatsu Y, Hibi M, Hashimoto H.

TILLING screening for medaka mutants supported by NBRP medaka

Hashimoto, H.

Visualization of oct3/4-expression cells in medaka.

Adachi T, Seki R, Sawatari E, Hibi M, Suzuki T, Hashimoto H.

A novel medaka mutant Da-2 showing a phenotype similar to Double-anal fin.

Nagao Y, Sawatari E, Shimizu A, Furutani-Seiki M, Fedorova S, Takeda H, Wakamatsu Y, Hibi M, Hashimoto H.

Left-sided expression of pitx2 at dorsal diencephalon and gut is maintained throughout larval development in flounders for metamorphic morphogenesis.

Kondo D, Fujinami Y, Uji S, Hashimoto H, Yokoi H, Suzuki T.

Expression analysis of nervous system marker genes reveals unique asymmetry formation of diencephalon in flounder larvae, correlated with one eye migration.

5) Washio Y, Aritaki M, Fujinami Y, Simizu D, Uji S, Hashimoto H, Suzuki T.

ヒラメ・カレイ類の左右非対称性を制御するpitx2の変態期再発現と、再発現に関連する左特異的エンハンサー内の核受容体応答配列

鈴木徹、近藤大地、ウ ショーミン、横井勇人、宇治督、橋本寿史

第３３回日本分子生物学会・第８３回日本生化学会合同大会 

メダカバイオリソースの技術的サポート2（TILLING、IR-LEGO、Cre/FLP-driver lineの作製）

浅川修一、尾田正二、亀井保博、北野健、木下政人、清水厚志、新屋みのり、竹内秀明、谷口善仁、出口友則、殿山泰弘、成瀬清、橋本寿史

第１５回小型魚類研究会 

メダカバイオリソースの技術的サポート（メダカゲノムシークエンスの精度向上と新規ゲノムブラウザーの開発）

浅川修一、尾田正二、亀井保博、北野健、木下政人、清水厚志、新屋みのり、竹内秀明、谷口善仁、出口友則、殿山泰弘、成瀬清、橋本寿史

第１５回小型魚類研究会 

Dynein axonemal intermediate chain 2 is required for formation of the left-right body axis and kidney in medaka. International conference

9th International Conference on Zebrafish Development and Genetics. 

Excessive and ectopic development of embryonic leucophores in medaka ml-3 mutant is caused by sox5 mutation. International conference

9th International Conference on Zebrafish Development and Genetics. 

メダカの運動性繊毛とPKD

橋本寿史

第９回PKD研究会 

*メダカ突然変異体をモデルとした腎繊毛異常症＝多発性嚢胞腎の研究

橋本寿史

ワークショップ「繊毛の形成機構と多彩な機能」、第３２回日本分子生物学会年会 

メダカmii変異体の解析：ヒトPCDのモデル生物へ向けて

長尾勇佑、前田礼、程晶磊、加村啓一郎、二瓶大地、越田澄人、武田洋幸、藤本豊士、若松佑子、日比正彦、橋本寿史

第１５回小型魚類研究会 

*Medaka mii mutant as a model for human primary ciliary dyskinesia

*A novel medaka mutant (Da-2) showing mirror-image duplication of the trunk-tail region.

*Detailed analysis of clonal characteristics arising in medaka nuclear transplants during transfer of somatic cell nuclei to non-enucleated diploidized eggs.

Glis3欠損マウスおよびメダカと繊毛

橋本寿史、若松佑子

第８回PKD研究会 

メダカ左右軸形成異常変異体miiの同定と解析

長尾勇佑、前田礼、渡辺直樹、吉田智也、橋本寿史、若松佑子、加村啓一郎、二瓶大地、越田澄人、武田洋幸

第３１回日本分子生物学会年会・第81回日本生化学会大会合同大会 

Transgenic medaka overexpressing dominant-negative form of myostatin, a counterpart of the double muscle mutation in cattle. International conference

5th World Fisheries Congress 

キンギョ水泡眼水疱内液の細胞増殖促進効果および未受精卵保存液としての利用

猿渡悦子、松村貴晴、橋本寿史、岩田靖宏、山本直生、若松佑子

第79回日本動物学会年会 

*メダカ体色変異体の色素胞形成異常と原因遺伝子

橋本寿史、若松佑子

第５回色素細胞シンポジウム「動物における色素産生制御機構の新展開」、第７９回日本動物学会年会 

二倍体化卵を用いた新しいメダカ核移植法におけるドナー核の細胞周期

カフタノフスカヤ エレナ、ブベンシコバ エカテリナ、足立朋子、橋本寿史、木下政人、若松佑子

第79回日本動物学会年会 

Localization of left-sided pitx2 expression in flounder larval diencephalon and analysis of succeeding asymmetric development of brain and optic nerves.

腎疾患モデルとしてのメダカ

橋本寿史、若松佑子

サテライトワークショップ「多分野で活躍する小型魚類」、第４１回日本発生生物学会年会 

Utilization of the fluid from eye sacs of Bubble-Eye Goldfish (Carassius auratus).

Polycystic kidney disease in medaka pc mutant is caused by a mutation in gli-similar3 (glis3) gene. International conference

The 4th Aquatic Animal Models of Human Disease Conference 

A study of the correlation between the cell cycle phases of recipient eggs and successful development of nuclear transplants generated by adult somatic cell nuclear transfer in medaka (Oryzias latipes). International conference

The 4th Aquatic Animal Models of Human Disease Conference 

メダカおよびマウスにおけるpc/GLIS3突然変異の表現型

橋本寿史、渡辺直樹、若松佑子

第7回PKD研究会 

胞胚期細胞核の付活卵への移植によるゼブラフィッシュ核移植個体の作製

服部学、橋本寿史、エカテリーナ・ブベンシコバ、若松佑子

第78回日本動物学会年会 

メダカにおけるネフロン新生を介した腎臓再生の可能性

渡辺直樹、加藤光博、橋本寿史、尾里建二郎、若松佑子

第40回日本発生生物学会年会 

ヒラメ間脳上部左側でのpitx2再発現に続いて起こる頭部および遊泳行動の非対称性形成

鷲尾洋平、有瀧真人、藤浪裕一朗、橋本寿史、鈴木徹

第40回日本発生生物学会年会 

多発性嚢胞腎を発症するメダカpc変異体の原因遺伝子の同定

橋本寿史、宮本理恵子、渡辺直樹、久保優子、古賀章彦、神藤智子、成田貴則、成瀬清、大石加寿子、野方恵子、新井理、小原雄治、武田洋幸、堀寛、若松佑子

日本分子生物学会2006フォーラム 

メダカの前腎および中腎の発生

橋本寿史、宮本理恵子、スヴェトラーナ・フェドロバ、原田智弘、平松健太郎、尾里建二郎、若松佑子

第12回小型魚類研究会 

メダカ多発性嚢胞腎変異体原因遺伝子pcの機能解析

橋本寿史、若松佑子

第6回PKD研究会 

多発性嚢胞腎メダカの開発

宮本兼玄、橋本整司、望月俊雄、小池隆夫、橋本寿史、尾里建二郎、若松佑子

第6回PKD研究会 

ヒラメ・カレイでは眼の非対称性形成開始時に間脳上部左側でpitx2が再発現する

鈴木徹、橋本寿史、有瀧真人、宇治督、黒川忠英

第39回日本発生生物学会年会（広島） 

メダカ多発性嚢胞腎原因遺伝子pcの変異領域の同定とアンチセンスオリゴによるノックダウン

渡辺直樹、宮本理恵子、古賀章彦、尾里建二郎、若松佑子、橋本寿史

第39回日本発生生物学会年会 

ヒラメ・カレイの片側眼球の移動に伴う脳の非対称性の形成とpitx2の新たな発現

鈴木徹、橋本寿史、有瀧真人、宇治督、黒川忠英

第28回日本分子生物学会年会 

Ogon/Sizzledによる背側化の分子機構

村岡修、矢部泰二郎、橋本寿史、日比正彦

第28回日本分子生物学会年会 

Analysis of medaka mutants with left-right axis abnormality.

International Symposium on Standardization of Medaka Bioresources 

Medaka Book

International Symposium on Standardization of Medaka Bioresources 

Development of medaka pronephros and mesonephros.

International Symposium on Standardization of Medaka Bioresources 

Three-dimensional reconstruction of pronephros and mesonephros in medaka.

International Symposium on Standardization of Medaka Bioresources 

メダカ突然変異体pcをモデルとした多発性嚢胞腎疾患の研究

橋本寿史

第35回日本腎臓学会西部学術大会 

ヒト多発性嚢胞腎疾患(PKD)モデルメダカpc突然変異体の原因遺伝子の同定

橋本寿史、渡辺直樹、宮本理恵子、尾里建二郎、若松佑子

第5回PKD研究会 

左右軸形成に異常を示すメダカ突然変異体の解析

吉田知也、渡辺直樹、橋本寿史、古谷－清木誠、若松佑子

日本発生生物学会第38回大会 

ヒラメ・カレイにユニークな眼の左右性の形成機構

鈴木徹、橋本寿史、有瀧真人

日本発生生物学会第38回大会）、シンポジウム「さまざまな動物の器官形成における左右性創出メカニズム」 

ヒト多発性嚢胞腎疾患モデルメダカpc突然変異体の原因遺伝子の同定

橋本寿史、宮本理恵子、渡辺直樹、久保優子、神藤智子、成田貴則、成瀬清、大石加寿子，野方恵子、新井理、小原雄治、武田洋幸、堀寛、若松佑子

日本発生生物学会第38回大会 

メダカにおける前腎および中腎の発生過程

宮本理恵子、スヴェトラーナ・フェドロバ、橋本寿史、若松佑子

日本発生生物学会第38回大会 

Three-dimentional reconstruction of the adult kidney development and nephrogenesis in Oryzias latipes.

CDB Symposium `Origin and Development of the Vertebrate Traits' 

Medaka pc mutant as a model of human polycystic kidney disease (PKD)

The 9th research Forum on Progressive Renal Diseases 

Medaka pc mutant as a model of human polycystic kidney disease (PKD)

メダカ多発性嚢胞腎の表現型

望月愛美子、原田智弘、松原礼奈、福田勝洋、橋本寿史、尾里建二郎、若松佑子

日本発生生物学会第37回大会 

The medaka model of polycystic kidney disease

The 8th research Forum on Progressive Renal Diseases 

メダカをモデルとした細胞分化制御機構の研究 Invited International conference

橋本寿史、成瀬 清

日本農芸化学会2018年度大会　シンポジウム「メダカ〜有用モデル生物としての産業応用への展開」  2018.3.18  人見清隆、橋本寿史

メダカをモデルとしたヒト遺伝性疾患の研究---多発性嚢胞腎疾患を中心とした分子遺伝学的研究

2004.4 - 2005.3

上原記念生命科学財団 

メダカをモデルとしたヒト遺伝病の研究－多発性嚢胞腎疾患原因遺伝子の同定

2004.4 - 2005.3

武田科学振興財団 

透明メダカを利用した腎臓の再生生物学に関する研究

2004

国内共同研究 

メダカ突然変異体をモデルとした皮膚色素異常症の研究

2002

学内共同研究 

医学・創薬に向けた小型魚類モデル利用推進ネットワーク

Role(s)：Planning, management, etc.,　Panel moderator, session chair, etc.

公益財団法人　科学技術交流財団  2011 - 2012