研究者詳細 - 片山　敬章

論文 - 片山　敬章

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The role of cardiopulmonary baroreflex on sympathetic vasomotor outflow and blood pressure regulation during dynamic exercise.

Katayama K, Ogoh S

Autonomic neuroscience : basic & clinical 260 巻頁： 103276 2025年4月

Intramuscular blood flow and muscle oxygenation of the vastus lateralis response to intermittent incremental muscle contractions 査読有り

Izumi K., Yamamori K., Katayama K., Kano Y., Tanaka N., and Akima H.

Experimental Physiology 110 巻頁： 106 - 114 2025年1月

Sympathoinhibition during cardiopulmonary baroreceptor loading is attenuated in older females. 査読有り国際共著

Katayama K., Shiozawa K., Lee J.B., Kondo H., Seo N., Ishida K., Millar P.J., Banno R., and Ogoh S.

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 327 巻頁： R88 - R96 2024年8月

Aging in femlaes has minimal effect on changes in celiac artery blood flow duringh dynamic light-intensity exercise 査読有り国際共著

Shiozawa K., Saito M., Lee J.B., Seo N., Kondo H., Kashima H., Yamaoka E.M., Ishida K., Millar P.J., and Katayama K.

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 327 巻頁： R14 - R24 2024年7月

Association of skeletal muscle oxidative capacity with muscle function, sarcopenia-related exercise performance, and intramuscular adipose tissue in older adults. 査読有り

Yoshiko A., Shiozawa K., Niwa S., Takahashi H., Koike T., Watanabe K., Katayama K., and Akima H.

GeoScience 2024年4月

新規考案のタンデムサイクルトレーナーにおける負荷の妥当性査読有り

31 巻頁： 21 - 25 2024年4月

Influence of sex on sympathetic vasomotor outflow responses to passive leg raising in young individuals 査読有り国際共著

Katayama K., Shiozawa K., Lee J.B., Seo N., Kondo H., Saito M., Ishida K., Millar P.J., Banno R., and Ogoh S.

Journal of Physiological Sciences 74 巻頁： 19 2024年3月

Impact of high-intensity interval hyperpnea on aerobic energy release and inspiratory muscle fatigue 招待有り査読有り

Sato S., Ishida K., Tanaka I.N., and Katayama K.

Respiratory Physiology & Neurobiology 319 巻頁： 104170 2024年1月

Effects of sex and menstrual cycle phase on celiac artery blood flow during dynamic moderate-intensity leg exercise in young individuals. 査読有り国際共著

97. Shiozawa K., Saito M., Lee J.B., Kashima H., Yamaoka E.M., Ishida K., Millar P.J., and Katayama K.

Journal of Applied Physiology 135 巻頁： 956 - 967 2023年10月

Differences between riding positions on oxygen uptake during tandem bicycle pedaling. 査読有り

Onodera S., Wada T., Ishida Y., Yoshioka A., So K., Hayashi S., Aratani Y., Matsuo K., Ishimoto Y., Takahara T., Yamaguchi H., and Katayama K.

Kawasaki Journal of Medical Welfare 2023年6月

An evaluation of change in the physical output in female youth football payers during a game 査読有り

Shigehiko Ogoh, Anna Oue, Hironori Watanabe, Shotaro Saito, Kento Dora, Nana Ogoh, Maki Osuga, Tetsuya Hasegawa, Keisho Katayama

European Journal of Sport Sciences 2 巻 ( 2 ) 頁： 1 - 7 2023年3月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：European Open Science Publishing

<jats:p>This study evaluated the time-to-time aerobic and anaerobic exercise intensities, calculated using the Global Positioning System (GPS), using laboratory measurements of individual physical fitness throughout the game in each female youth football player. In addition, we examine if the anaerobic exercise index calculated by only GPS data presents this evaluation to examine its validity. In the laboratory, the oxygen uptake (V̇O2) matched with moving speed was identified during an incremental exercise test on the treadmill, and the ventilatory (anaerobic) threshold was also analysed to identify individual aerobic and anaerobic exercise intensities. Using these laboratory data, time-to-time changes in individual relative running intensity (aerobic and anaerobic) were visualised from individual GPS data during a football game, and an individual’s sprint output (ability) during the game was evaluated. An index of running intensity and the percentage of anaerobic exercise over the game provided by the GPS software (equivalent distance index [%EDI] and anaerobic index [AI]) did not present the actual individual exercise intensity (ICC(2,1), absolute agreement=−0.031; P=0.596) and percentage of anaerobic exercise (ICC(2,1), absolute agreement=−0.003; P=0.698) values during the game, respectively. These findings suggest that only GPS measurement cannot present the individual actual exercise intensity during a football game because of different individual fitness levels to the same running speed.</jats:p>

DOI： 10.24018/ejsport.2023.2.2.49

Upper and lower limb muscle sympathetic responses to contralateral exercise in healthy humans: a pilot study. 査読有り

Lee J.B., Katayama K., and Miller P.J.

Autonomic Neuroscience 243 巻頁： 103024 2022年12月

Upper and lower limb muscle sympathetic responses to contralateral exercise in healthy humans: A pilot study.

Lee JB, Katayama K, Millar PJ

Autonomic neuroscience : basic & clinical 243 巻頁： 103024 2022年12月

Mixed effects of moderate exercise and subsequent various food ingestion on breath acetone. 査読有り

Nagamine K., Mineta D., Ishida K., Katayama K., and Kondo T.

Journal of Breath Research 頁： 016004 2022年11月

Blood pressure and coeliac artery blood flow responses during increased inspiratory muscle work in healthy males. 国際誌

Shiozawa K, Kashima H, Mizuno S, Ishida K, Katayama K

Experimental Physiology 107 巻 ( 9 ) 頁： 1094 - 1104 2022年9月

Blood pressure and celiac artery blood flow responses during increased inspiratory muscle work in healthy males. 査読有り

Shiozawa K., Kashima H., Mizuno S., Ishida K., Katayama K.

Experimental Physiology 107 巻頁： 1094 - 1104 2022年9月

Influence of cardiac output response to the onset of exercise on cerebral blood flow 査読有り

Saito S., Washio T., Watanabe H., Katayama K., and Ogoh S.

European Journal of Applied Physiology 2022年8月

Sympathetic vasomotor outflow during low-intensity leg cycling in heathy older males. 査読有り

Katayama K., Saito M., Ishida K., Shimizu K., Shiozawa K., Mizuno S., and Ogoh S.

Experimental Physiology 2022年8月

Cerebral blood velocity and arterial pressure at the onset of exercise: potential influence of the cardiopulmonary baroreflex.

Ogoh S, Saito S, Watanabe H, Katayama K

Clinical autonomic research : official journal of the Clinical Autonomic Research Society 2022年2月

Relationship between respiratory muscle endurance and dyspnea during high-intensity exercise in trained distance runners.

Mizuno S, Suzuki Y, Goto K, Takao K, Sumi D, Ishida K, Mizuno F, Katayama K

Respiratory Physiology & Neurobiology 296 巻頁： 103812 2022年2月

Effect of moderate- or high-intensity inspiratory muscle strength training on maximal Inspiratory mouth pressure and swimming performance in highly trained competitive swimmers.

Ohya T, Kusanagi K, Koizumi J, Ando R, Katayama K, Suzuki Y

International Journal of Sports Physiology and Performance 17 巻 ( 3 ) 頁： 343 - 349 2021年10月

Respiratory modulation of sympathetic vasomotor outflow during graded leg cycling 査読有り国際共著

Katayama K., Dominelli P.B., Foster G.., Kipp S., Leahy M.G., Ishida K., and Sheel A.W.

Journal of Applied Physiology 131 巻頁： 858 - 867 2021年6月

Age and sex differences in blood pressure responses during hyperpnoea.

Shimizu K, Shiozawa K, Ishida K, Saito M, Mizuno S, Akima H, Katayama K

Experimental Physiology 106 巻 ( 3 ) 頁： 736 - 747 2021年3月

Effects of sex and age on blood pressure response during voluntary normocapnic hyperpnea(和訳中)

Shimizu Kaori, Shiozawa Kana, Saito Mitsuru, Ishida Koji, Mizuno Sahiro, Akima Hiroshi, Katayama Keisho

The Journal of Physical Fitness and Sports Medicine 9 巻 ( 6 ) 頁： 290 - 290 2020年11月

Sex differences in blood flow distribution during dynamic leg exercise with increased inspiratory muscle work(和訳中)

Shiozawa Kana, Shimizu Kaori, Saito Mitsuru, Ishida Koji, Mizuno Sahiro, Katayama Keisho

The Journal of Physical Fitness and Sports Medicine 9 巻 ( 6 ) 頁： 294 - 294 2020年11月

Blood pressure and limb blood flow responses during hyperpnoea are not affected by menstrual cycle phase in young women. 査読有り

Shimizu K, Shiozawa K, Ishida K, Saito M, Mizuno S, Akima H, Katayama K

Respiratory Physiology & Neurobiology 275 巻頁： 103387 2020年4月

The interactive effects of acute exercise and hypoxia on cognitive performance: A narrative review. 招待有り国際共著

Ando S, Komiyama T, Sudo M, Higaki Y, Ishida K, Costello JT, Katayama K

Scandinavian Journal of Medicine & Science in Sports 30 巻 ( 3 ) 頁： 384-398 2020年3月

Effect of inspiratory resistive training on diaphragm shear modulus and accessory inspiratory muscle activation. 査読有り

Ando R, Ohya T, Kusanagi K, Koizumi J, Ohnuma H, Katayama K, Suzuki Y

Applied Physiology, Nutrition, and Metabolism 2020年2月

The hyperpnoea of exercise in health: Respiratory influences on neurovascular control 招待有り査読有り国際共著

Sheel A.W., Taylor J.L., and Katayama K.

Experimental Physiology 2020年2月

Muscle deoxygenation and neuromuscular activation in synergistic muscles during intermittent exercise under hypoxic conditions. 査読有り

Yoshiko A, Katayama K, Ishida K, Ando R, Koike T, Oshida Y, Akima H

Scientific Reports 10 巻 ( 1 ) 頁： 295 2020年1月

Muscle pump-induced inhibition of sympathetic vasomotor outflow during low-intensity leg cycling is attenuated by muscle metaboreflex activation. 査読有り

Katayama K, Barbosa TC, Kaur J, Young BE, Nandadeva D, Ogoh S, Fadel PJ

Journal of Applied Physiology (Bethesda, Md. : 1985) 128 巻 ( 1 ) 頁： 1-7 2020年1月

6週間の呼吸筋トレーニングがエリート水泳選手の横隔膜と呼吸補助筋の機能に及ぼす効果

安藤良介, 大家利之, 草薙健太, 小泉潤, 大沼勇人, 片山敬章, 鈴木康弘

Journal of Training Science for Exercise and Sport 31 巻 ( 4 ) 頁： 231 - 231 2020年1月

認知課題の違いがデュアルタスク遂行能力に及ぼす影響(Effect of different cognitive tasks on dual-task performance)

Zhang Luyu, Sudo Mizuki, Ando Soichi, Katayama Keisho, Ishida Koji

The Journal of Physical Fitness and Sports Medicine 8 巻 ( 6 ) 頁： 272 - 272 2019年11月

運動-認知二重課題開始時の呼吸循環応答(Cardio-respiratory responses at the onset of motor-cognitive dual-task)

Ishida Koji, Zhang Luyu, Sudo Mizuki, Ando Soichi, Katayama Keisho

The Journal of Physical Fitness and Sports Medicine 8 巻 ( 6 ) 頁： 299 - 299 2019年11月

Effects of respiratory muscle endurance training in hypoxia on running performance. 査読有り

Katayama K, Goto K, Ohya T, Iwamoto E, Takao K, Kasai N, Sumi D, Mori H, Ishida K, Shimizu K, Shiozawa K, Suzuki Y

Medicine and Science in Sports and Exercise 51 巻 ( 7 ) 頁： 1477-1486 2019年7月

Muscle sympathetic nerve activity during exercise.

Katayama K, Saito M

The journal of physiological sciences : JPS 69 巻 ( 4 ) 頁： 589-598 2019年7月

Effect of Increased Respiratory Muscle Activation on Blood Flow to Inactive and Active Limb Muscles

Shiozawa Kana, Goto Kanako, Shimizu Kaori, Saito Mitsuru, Ishida Koji, Zhang Luyu, Sheel William, Katayama Keisho

MEDICINE AND SCIENCE IN SPORTS AND EXERCISE 51 巻 ( 6 ) 頁： 488-488 2019年6月

Inspiratory Muscle Strength And Diaphragm Thickness In Elderly Women

Shimizu Kaori, Shiozawa Kana, Watanabe Kohei, Saito Mitsuru, Ishida Koji, Akima Hiroshi, Katayama Keisho

MEDICINE AND SCIENCE IN SPORTS AND EXERCISE 51 巻 ( 6 ) 頁： 655-655 2019年6月

Work of breathing influences muscle sympathetic nerve activity during semi-recumbent cycle exercise.

Dominelli PB, Katayama K, Vermeulen TD, Stuckless TJR, Brown CV, Foster GE, Sheel AW

Acta physiologica (Oxford, England) 225 巻 ( 4 ) 頁： e13212 2019年4月

Effect of increased inspiratory muscle work on blood flow to inactive and active limbs during submaximal dynamic exercise.

Katayama K, Goto K, Shimizu K, Saito M, Ishida K, Zhang L, Shiozawa K, Sheel AW

Experimental physiology 104 巻 ( 2 ) 頁： 180-188 2019年2月

Neuromuscular activation of the knee and hip extensor muscles during high-intensity interval and moderate-intensity constant cycling.

Ando R, Kondo S, Katayama K, Ishida K, Akima H

Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology 44 巻頁： 64-69 2019年2月

Acute reduction in posterior cerebral blood flow following isometric handgrip exercise is augmented by lower body negative pressure.

Washio T, Vranish JR, Kaur J, Young BE, Katayama K, Fadel PJ, Ogoh S

Physiological reports 6 巻 ( 20 ) 頁： e13886 2018年10月

High-intensity muscle metaboreflex activation attenuates cardiopulmonary baroreflex-mediated inhibition of muscle sympathetic nerve activity

Katayama Keisho, Kaur Jasdeep, Young Benjamin E., Barbosa Thales C., Ogoh Shigehiko, Fadel Paul J.

JOURNAL OF APPLIED PHYSIOLOGY 125 巻 ( 3 ) 頁： 812-819 2018年9月

Diaphragmatic shear modulus at various submaximal inspiratory mouth pressure levels

Chino Kentaro, Ohya Toshiyuki, Katayama Keisho, Suzuki Yasuhiro

RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY 252 巻頁： 52-57 2018年6月

Blunted Sympathetic Vasomotor Outflow To Inspiratory Resistive Breathing During Exercise In Women Compared to Men

Katayama Keisho, Smith Joshua R, Goto Kanako, Shimizu Kaori, Saito Mitsuru, Ishida Koji, Koike Teruhiko, Iwase Satoshi, Harms Craig A

MEDICINE AND SCIENCE IN SPORTS AND EXERCISE 50 巻 ( 5 ) 頁： 284-285 2018年5月

Elevated sympathetic vasomotor outflow in response to increased inspiratory muscle activity during exercise is less in young women compared with men

Katayama Keisho, Smith Joshua R., Goto Kanako, Shimizu Kaori, Saito Mitsuru, Ishida Koji, Koike Teruhiko, Iwase Satoshi, Harms Craig A.

EXPERIMENTAL PHYSIOLOGY 103 巻 ( 4 ) 頁： 570-580 2018年4月

Blood pressure response during normocapnic hyperpnoea is blunted in young women compared to men

Shimizu Kaori, Goto Kanako, Ishida Koji, Saito Mitsuru, Akima Hiroshi, Katayama Keisho

RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY 247 巻頁： 52-56 2018年1月

Cognitive function during exercise under severe hypoxia

Komiyama Takaaki, Katayama Keisho, Sudo Mizuki, Ishida Koji, Higaki Yasuki, Ando Soichi

SCIENTIFIC REPORTS 7 巻 2017年8月

Blood Pressure Response During Hyperpnoea Is Lower in Women Compared with Men

Shimizu Kaori, Katayama Keisho, Goto Kanako, Ishida Koji, Akima Hiroshi

MEDICINE AND SCIENCE IN SPORTS AND EXERCISE 49 巻 ( 5 ) 頁： 797-797 2017年5月

Respiratory Muscle Endurance And Cardiovascular Response To Hyperpnoea After Respiratory Muscle Training In Hypoxia

Katayama Keisho, Iwamoto Erika, Ohya Toshiyuki, Goto Kazushige, Takao Kenji, Kasai Nobukazu, Sumi Daichi, Ishida Koji, Suzuki Yasuhiro

MEDICINE AND SCIENCE IN SPORTS AND EXERCISE 49 巻 ( 5 ) 頁： 796-796 2017年5月

自転車エルゴメータによる高強度インターバル運動と一定負荷運動時の大腿四頭筋の神経筋活動

近藤翔平, 安藤良介, 片山敬章, 石田浩司, 秋間広, 秋間広, 石田浩司, 片山敬章, 安藤良介, 近藤翔平

総合保健体育科学 40 巻 ( 1 ) 頁： 21 - 27 2017年

運動時の循環調節に対する呼吸筋活動の影響

片山敬章

体力科学 66 巻 ( 1 ) 頁： 15 - 15 2017年

A Prospective, Multicenter, Randomized Phase II Study to Evaluate the Efficacy and Safety of Eculizumab in Patients with Guillain-Barré Syndrome (GBS): Protocol of Japanese Eculizumab Trial for GBS (JET-GBS).

Yamaguchi N, Misawa S, Sato Y, Nagashima K, Katayama K, Sekiguchi Y, Iwai Y, Amino H, Suichi T, Yokota T, Nishida Y, Kohara N, Hirata K, Nishiyama K, Yabe I, Kaida KI, Suzuki N, Nodera H, Tsuji S, Koike H, Kira JI, Hanaoka H, Kusunoki S, Kuwabara S, JET-GBS Group

JMIR research protocols 5 巻 ( 4 ) 頁： e210 2016年11月

Blunted blood pressure response during hyperpnoea in endurance runners.

Itoh Y, Katayama K, Iwamoto E, Goto K, Suzuki Y, Ohya T, Takao K, Ishida K

Respiratory physiology & neurobiology 230 巻頁： 22-8 2016年8月

Reduction In Oxygen Delivery Under Severe Hypoxia Affects Cognitive Function During Moderate Exercise: 1537 Board #190 June 2, 9: 00 AM - 10: 30 AM. 査読有り

Komiyama T, Katayama K, Sudo M, Ishida K, Higaki Y, Ando S

Medicine and science in sports and exercise 48 巻 ( 5 Suppl 1 ) 頁： 419 2016年5月

Hypoxia attenuates cardiopulmonary reflex control of sympathetic nerve activity during mild dynamic leg exercise.

Katayama K, Ishida K, Saito M, Koike T, Ogoh S

Experimental physiology 101 巻 ( 3 ) 頁： 377-86 2016年3月

Responses of sex steroid hormones to different intensities of exercise in endurance athletes.

Sato K, Iemitsu M, Katayama K, Ishida K, Kanao Y, Saito M

Experimental physiology 101 巻 ( 1 ) 頁： 168-75 2016年1月

Hypoxia exaggerates inspiratory accessory muscle deoxygenation during hyperpnoea. 査読有り

Katayama K., Suzuki Y., Hoshikawa M., Ohya T., Oriishi M., Itoh Y., and Ishida K.

Respir. Physiol. Neurobiol. 211 巻頁： 1-18 2015年6月

Exercise intensity modulates brachial artery retrograde blood flow and shear rate during leg cycling in hypoxia. 査読有り

Iwamoto E., Katayama K., and Ishida K.

Physiol. Rep. 3 巻頁： e12423 2015年6月

Exercise intensity modulates brachial artery retrograde blood flow and shear rate during leg cycling in hypoxia.

Iwamoto E, Katayama K, Ishida K

Physiological reports 3 巻 ( 6 ) 2015年6月

Sympathetic vasomotor outflow and blood pressure increase during exercise with expiratory resistance. 査読有り

Katayama K., Itoh Y., Saito M., Koike T., and Ishida K.

Physiol. Rep. 3 巻頁： e12421 2015年5月

Sympathetic vasomotor outflow and blood pressure increase during exercise with expiratory resistance.

Katayama K, Itoh Y, Saito M, Koike T, Ishida K

Physiological reports 3 巻 ( 5 ) 2015年5月

Suitability of modified tandem-bicycle ergometer. 査読有り

Onodera S., Yoshioka A., Yamaguchi H., Matsumoto N., Nishimura K., Kawano H., Saito T., Arakane K., Hayashi S., Takagi Y., Wada T., Murata M., Seki K. Nose Y., Raum B. W., Katayama K., and Ogita F.

J. Phy. Fit. Sports Med. 4 巻頁： 249-251 2015年

Sympathetic vasomotor outflow and blood pressure increase during exercise with expiratory resistance. 査読有り

Katayama K., Itoh Y., Saito M., Koike T., and Ishida K.

Physiol. Rep. 3 巻頁： e12421 2015年

Hypoxia exaggerates inspiratory accessory muscle deoxygenation during hyperpnoea. 査読有り

Katayama K., Suzuki Y., Hoshikawa M., Ohya T., Oriishi M., Itoh Y., and Ishida K.

Respir. Physiol. Neurobiol. 211 巻頁： 1-8 2015年

Enhanced muscle pump during mild dynamic leg exercise inhibits sympathetic vasomotor outflow.

Katayama K, Ishida K, Saito M, Koike T, Hirasawa A, Ogoh S

Physiological reports 2 巻 ( 7 ) 2014年7月

Enhanced muscle pump during mild dynamic leg exercise inhibits sympathetic vasomotor outflow 査読有り

Katayama K., Ishida K., Saito M., Koike T., Hirasawa A., and Ogoh S.

Physiol Rep 2 巻 ( 7 ) 頁： e12070 2014年

Flow-mediated dilation in the inactive limb following acute hypoxic exercise. 査読有り

Katayama K., Yamashita S., Iwamoto E., and Ishida K.

Clin. Physiol. Func. Imaging. 2014年

Retrograde blood flow in the inactive limb is enhanced during constant-load leg cycling in hypoxia.

Iwamoto E, Katayama K, Yamashita S, Oshida Y, Ishida K

European journal of applied physiology 113 巻 ( 10 ) 頁： 2565-75 2013年10月

Hypoxic effects on sympathetic vasomotor outflow and blood pressure during exercise with inspiratory resistance.

Katayama K, Yamashita S, Ishida K, Iwamoto E, Koike T, Saito M

American journal of physiology. Regulatory, integrative and comparative physiology 304 巻 ( 5 ) 頁： R374-82 2013年3月

低酸素トレーニングと生活習慣病ーエネルギー代謝・内分泌系への影響ー

片山敬章, 後藤一成

体育の科学 63 巻 ( 3 ) 頁： 237-241 2013年3月

The effect of acute exercise in hypoxia on flow-mediated vasodilation.

Katayama K, Fujita O, Iemitsu M, Kawano H, Iwamoto E, Saito M, Ishida K

European journal of applied physiology 113 巻 ( 2 ) 頁： 349-57 2013年2月

Hypoxic effects on sympathetic vasomotor outflow and blood pressure during exercise with inspiratory resistance 査読有り

Katayama K., Yamashita S., Ishida K., Iwamoto E., Koike T., and Saito M.

Am. J. Appl. Physiol. Regul. Integr. Physiol. 304 巻頁： R374-R382 2013年

The effect of acute exercise in hypoxia on flow-mediated vasodilation 査読有り

Katayama K., Fujita O., Iemitsu M., Kawano H., Iwamoto E., Saito M., and Ishida K

Eur. J. Appl. Physiol. 113 巻頁： 349-357 2013年

04生-29-口-14 持久能鍛錬者と非鍛錬者の異なる運動負荷における性ホルモン濃度変化の比較(04 運動生理学,一般研究発表抄録)

佐藤幸治, 家光素行, 片山敬章, 石田浩司, 金尾洋治, 斉藤満

日本体育学会大会予稿集 64 巻頁： 165 - 165 2013年

The effect of acute exercise in hypoxia on flow-mediated vasodilation.

Katayama K, Fujita O, Iemitsu M, Kawano H, Iwamoto E, Saito M, Ishida K

Eur J Appl Physiol 9 巻頁： 47 2012年6月

Hypoxia augments oscillatory blood flow in brachial artery during leg cycling.

Iwamoto E, Katayama K, Oshida Y, Ishida K

Medicine and science in sports and exercise 44 巻 ( 6 ) 頁： 1035-42 2012年6月

Inspiratory muscle fatigue increases sympathetic vasomotor outflow and blood pressure during submaximal exercise.

Katayama K, Iwamoto E, Ishida K, Koike T, Saito M

American journal of physiology. Regulatory, integrative and comparative physiology 302 巻 ( 10 ) 頁： R1167-75 2012年5月

呼吸, 循環, 体温・体液調節の連関と運動パフォーマンスへの影響

片山敬章

体力科學 61 巻 ( 1 ) 頁： 31 - 31 2012年2月

Inspiratory muscle fatigue increases sympathetic vasomotor outflow and blood pressure during submaximal exercise 査読有り

Katayama K., Iwamoto E., Ishida K., Koike T., and Saito M.

Am. J. Physiol. Regul. Integr. Comp. Physiol. 302 巻頁： R1167-R1175 2012年

「呼吸」-「循環」連関

片山敬章

体力科学 61 巻 ( 1 ) 頁： 34 - 34 2012年

Hypoxia augments muscle sympathetic neural response to leg cycling.

Katayama K, Ishida K, Iwamoto E, Iemitsu M, Koike T, Saito M

American journal of physiology. Regulatory, integrative and comparative physiology 301 巻 ( 2 ) 頁： R456-64 2011年8月

二人乗り自転車エルゴメーター運動時の心拍数と酸素摂取量変化前乗りと後乗りの比較

小野寺昇, 片山敬章, 荻田太, 吉岡哲, 河野寛, 西村一樹, 山口英峰, 関和俊, 高橋康輝, BAIK Wooram, 枝松千尋, 飯田智行, 荒金圭太, 斎藤辰哉, 野瀬由佳, 高木祐介, 松本希, 高原皓全, 古本佳代

岡山体育学研究 ( 18 ) 頁： 45 2011年3月

Hypoxia augments muscle sympathetic neural response to leg cycling 査読有り

Katayama K, Ishida K, Iwamoto E, Iemitsu M, and Saito M.

301 巻頁： R456-R464 2011年

The effect of intense interval cycle-training on unloading-induced dysfunction and atrophy in the human calf muscle.

Hotta N, Ishida K, Sato K, Koike T, Katayama K, Akima H

Journal of physiological anthropology 30 巻 ( 1 ) 頁： 29 - 35 2011年

Aerobic exercise capacity and muscle volume after lower limb suspension with exercise countermeasure.

Sato K, Katayama K, Hotta N, Ishida K, Akima H

Aviation, space, and environmental medicine 81 巻 ( 12 ) 頁： 1085-91 2010年12月

Muscle deoxygenation during sustained and intermittent isometric exercise in hypoxia.

Katayama K, Yoshitake Y, Watanabe K, Akima H, Ishida K

Medicine and science in sports and exercise 42 巻 ( 7 ) 頁： 1269-78 2010年7月

Substrate utilization during exercise and recovery at moderate altitude.

Katayama K, Goto K, Ishida K, Ogita F

Metabolism: clinical and experimental 59 巻 ( 7 ) 頁： 959-66 2010年7月

対抗措置としての人工重力負荷と運動負荷が模擬微小重力暴露後の骨代謝デコンディショニングにおよぼす効果

西村直記, 岩瀬敏, 塩澤友規, 菅屋潤壹, 清水祐樹, 高田真澄, 犬飼洋子, 佐藤麻紀, Kanikowska D., 鈴木里美, 渡邉順子, 石田浩司, 秋間広, 片山敬章, 平柳要, 増尾善久, 間野忠明

日本生理学雑誌 72 巻 ( 2 ) 頁： 72 - 72 2010年2月

Substrate utilization during exercise and recovery at moderate altitude 査読有り

Katayama, K., K. Goto, K. Ishida, and F. Ogita

Metabolism 59 巻頁： 959-966 2010年

Muscle deoxygenation during sustained and intermittent isometric exercise in hypoxia 査読有り

Katayama, K., Y. Yoshitake, K. Watanabe, H. Akima, and K. Ishida

Med. Sci. Sports Exerc. 42 巻頁： 1269-1278 2010年

模擬微小重力暴露後に生ずる骨代謝デコンディショニングに対する対抗措置の効果

西村直記, 岩瀬敏, 塩澤友規, 菅屋潤壹, 高田真澄, 犬飼洋子, 佐藤麻紀, Kanikowska Dominika, 鈴木里美, 石田浩司, 秋間広, 片山敬章, 平柳要, 増尾善久, 間野忠明

宇宙航空環境医学 46 巻 ( 4 ) 頁： 80 - 80 2009年12月

Electromyographic analysis of hip adductor muscles during incremental fatiguing pedaling exercise.

Watanabe K, Katayama K, Ishida K, Akima H

European journal of applied physiology 106 巻 ( 6 ) 頁： 815-25 2009年8月

Effect of Intensive Interval Training during Unloading on Muscle Deoxygenation Kinetics 査読有り

Y. Furuichi, K. Masuda, H. Takakura, N. Hotta, K. Ishida, K. Katayama, S. Iwase, H. Akima

INTERNATIONAL JOURNAL OF SPORTS MEDICINE 30 巻 ( 8 ) 頁： 563 - 568 2009年8月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：GEORG THIEME VERLAG KG

The present study investigated the effects of intensive interval training during 20-day of unloading on local muscle oxygenation kinetics evaluated by near infrared spectroscopy technique (NIRS). Eleven adult men completed 20-day unloading and were divided into two groups; the control (CON) group and training (TR) group. The TR group engaged in exercise training sessions that consisted of one-legged submaximal cycle exercise using the unloaded leg at 60 similar to 80% of (V) over dotO(2peak) with intermittent rest periods, 25 min/day every other day. All Subjects performed isometric knee extension exercise at 50% of their maximum voluntary contraction force before and after unloading. NIRS Delta[deoxy-Hb/Mb] signal was recorded from m. vastus lateralis and was fitted to an exponential equation in order to determine the kinetics parameters. The time constant (tau) of the % Delta[deoxy-Hb/Mb] was unchanged in the TR group, while it significantly increased in the CON group after unloading(pre, 5.0 +/- 1.0; post, 7.4 +/- 1.0s). It is concluded that 20-day unloading increased the T, suggesting deterioration of capacity for oxidative phosphorylation and oxygen utilization in a skeletal muscle. Additionally, the preservation Of T in the TR group suggested that intensive interval training could have an impact on the maintenance of muscle oxidative metabolism during unloading.

DOI： 10.1055/s-0029-1202824

Web of Science

PubMed

Cycle ergometer exercise to counteract muscle atrophy during unilateral lower limb suspension.

Akima H, Hotta N, Sato K, Ishida K, Koike T, Katayama K

Aviation, space, and environmental medicine 80 巻 ( 7 ) 頁： 652-6 2009年7月

Effect of two durations of short-term intermittent hypoxia on ventilatory chemosensitivity in humans.

Katayama K, Ishida K, Iwasaki K, Miyamura M

European journal of applied physiology 105 巻 ( 5 ) 頁： 815-21 2009年3月

*Effect of two durations of short-term intermittent hypoxia on ventilatory chemosensitivity in humans. 査読有り

Katayama, K., K. Ishida, K. Iwasaki, and M. Miyamura.

Eur. J. Appl. Physiol. 105 巻頁： 483-491 2009年

記述言語：英語掲載種別：研究論文（学術雑誌）

The purpose of this study was to clarify the influence of duration of intermittent hypoxia per day on ventilatory chemosensitivity. Subjects were assigned to 3 different groups according to the duration of exposure to intermittent hypoxia (12.3% O2): A first group (H-1, n=6) was exposed to hypoxia for 1 hour per day, the second group (H-2, n=6) was exposed for 3 hours per day, and the third (C, n= 7) was used as control. Hypoxic and hypercapnic ventilatory responses (HVR and HCVR) were determined before and after 1 week of intermittent hypoxia. HVR was increased significantly (P<0.05) after intermittent hypoxia in both the H-1 and H-2 groups. However, there was no significant difference in magnitude of increased HVR between H-1 and H-2 groups. HCVR did not show any changes in all groups after intermittent hypoxia. These results suggest that 1 hour of daily exposure is as equally effective as 3 hours of daily exposure to severe hypoxia for a short period for enhancing ventilatory chemosensitivity to hypoxia.

Effect of intensive interval cycling training during unilateral lower limb unloading on aerobic capacity

Keisho Katayama, Kohei Sato, Norio Hotta, Koji Ishida, Kohei Watanabe, Kazumi Masuda, Motohiko Miyachi, Teruhiko Koike, Hiroshi Akima

Japanese Journal of Physical Fitness and Sports Medicine 57 巻 ( 1 ) 頁： 84 2008年

Chronic intermittent hypoxia increases the CO2 reserve in sleeping dogs

Katayama Keisho, Smith Curtis A., Henderson Kathleen S., Dempsey Jerome A.

JOURNAL OF APPLIED PHYSIOLOGY 103 巻 ( 6 ) 頁： 1942-1949 2007年12月

Ventilatory and circulatory responses at the onset of dominant and non-dominant limb exercise.

Hotta N, Yamamoto K, Sato K, Katayama K, Fukuoka Y, Ishida K

European journal of applied physiology 101 巻 ( 3 ) 頁： 347 - 58 2007年10月

Effect of arterial oxygenation on quadriceps fatigability during isolated muscle exercise.

Katayama K, Amann M, Pegelow DF, Jacques AJ, Dempsey JA

American journal of physiology. Regulatory, integrative and comparative physiology 292 巻 ( 3 ) 頁： R1279-86 2007年3月

Intermittent hypoxia does not increase exercise ventilation at simulated moderate altitude. 査読有り

Katayama, K., K. Sato, N. Hotta, K. Ishida, K. Iwasaki, and M. Miyamura.

Int. J. Sports Med. 28 巻頁： 480-487 2007年

記述言語：英語掲載種別：研究論文（学術雑誌）

Recent human studies have shown that resting hypoxic ventilatory response (HVR), which is an index of ventilatory chemosensitivity to hypoxia, increased after short-term intermittent hypoxia at rest. In addition, intermittent hypoxia leads to increases in ventilation and arterial oxygen saturation (SaO (2)) during exercise at simulated high altitude, with the increase in ventilation correlated to the change in HVR. However, no study has been made to clarify the relationship between ventilatory chemosensitivity and the exercise ventilation at moderate altitude following intermittent hypoxia during a resting state. The purpose of the present study, therefore, was to elucidate whether intermittent hypoxia at rest induces the increase in ventilation during exercise at moderate altitude that is accompanied by an increase in hypoxic chemosensitivity. Eighteen trained male runners were assigned to three groups, i.e., the first hypoxic group (H-1 group, n = 6), the second hypoxic group (H-2 group, n = 6), and a control group (C group, n = 6). The hypoxic tent system was utilized for intermittent hypoxia, and the oxygen levels in the tent were maintained at 15.5 +/- 0.1 % (simulated 2500 m altitude) for the H-1 group and 12.3 +/- 0.2 % (simulated 4300 m altitude) for the H-2 group. The H-1 and H-2 groups spent 1 hour per day in the hypoxic tent for 1 week. Maximal and submaximal exercise tests while breathing 15.5 +/- 0.01 % O (2) (simulated altitude of 2500 m) were performed before and after intermittent hypoxia. Resting HVR was also determined in each subject using a progressive isocapnic hypoxic method. In the H-2 group, HVR increased significantly (p < 0.05) following intermittent hypoxia, while no change in HVR was found in the H-1 or C group. Neither ventilation nor SaO (2) during maximal and submaximal exercise at a simulated altitude of 2500 m were changed in either group after 1 hour per day for 1 week of intermittent hypoxia. These results suggest that the change i

Chronic intermittent hypoxia increases the CO2 reserve in sleeping dogs. 査読有り

Katayama, K., C. A. Smith, K. S. Henderson, and J. A. Dempsey.

J. Appl. Physiol. 103 巻頁： 1973-1978 2007年

*The effect of arterial oxygenation on quadriceps fatigability during isolated muscle exercise. 査読有り

Katayama, K., M. Amann, D. F. Pagelow, A. J. Jacques, and J. A. Dempsey.

Am. J. Physiol. Regul. Integr. Physiol. 292 巻頁： R1279-R1286 2007年

記述言語：英語掲載種別：研究論文（学術雑誌）

The effect of various levels of oxygenation on quadriceps muscle fatigability during isolated muscle exercise was assessed in six male subjects. Twitch force (Qtw) was assessed using supra-maximal magnetic femoral nerve stimulation. In Experiment I, maximal voluntary contraction (MVC) and Qtw of resting quadriceps muscle were measured in nomoxia [arterial O2 saturation (SpO2) = 98.4; NORM], acute-hypoxia (SpO2 = 74.6%; HYPO), and acute-hyperoxia (SpO2 = 100%; HYPER). No significant differences were found for MVC and Qtw among the three FIO2s. In Experiment II, the subjects performed three sets of nine, intermittent, isometric, unilateral, submaximal quadriceps contractions (62% MVC) while breathing each FIO2. Qtw was assessed before and after exercise, and myoelectrical activity of the vastus lateralis was obtained during exercise. The percent reduction of twitch force (potentiated Qtw) in HYPO (-27.0%) was significantly (P<0.05) greater than those in NORM (-21.4%) and HYPER (-19.9%). The increase in integrated electromyogram over the course of the nine contractions in HYPO (15.4%) was higher (P<0.05) than in NORM (7.2%) or HYPER (6.7%). These results demonstrate that quadriceps muscle fatigability during isolated muscle exercise is exacerbated in acute hypoxia, and these effects were independent of the relative exercise intensity.

Comments on Point:Counterpoint "Positive effects of intermittent hypoxia (live high:train low) on exercise performance are/are not mediated primarily by augmented red cell volume".

Katayama K

Journal of applied physiology (Bethesda, Md. : 1985) 99 巻 ( 6 ) 頁： 2460 2005年12月

Intensive cycle training with artificial gravity maintains muscle size during bed rest.

Akima H, Katayama K, Sato K, Ishida K, Masuda K, Takada H, Watanabe Y, Iwase S

Aviation, space, and environmental medicine 76 巻 ( 10 ) 頁： 923-9 2005年10月

Changes In Ventilatory Responses To Hypercapnia And Hypoxia After Intermittent Hypoxia In Trained Athletes

Katayama Keisho, Sato Kohei, Matsuo Hiroshi, Hotta Norio, Sun Zhihu, Ishida Koji, Iwasaki Ken-ichi, Miyamura Miharu

MEDICINE AND SCIENCE IN SPORTS AND EXERCISE 37 巻頁： S294-S294 2005年5月

Changes in ventilatory responses to hypercapnia and hypoxia after intermittent hypoxia in humans

Katayama K, Sato K, Matsuo H, Hotta N, Sun ZH, Ishida K, Iwasaki K, Miyamura M

RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY 146 巻 ( 1 ) 頁： 55-65 2005年3月

Vestibulo-cardiorespiratory responses at the onset of chair rotation in endurance runners.

Sato K, Katayama K, Katayama N, Hotta N, Ishida K, Miyamura M

The Japanese journal of physiology 55 巻 ( 1 ) 頁： 11-8 2005年2月

Effect of a repeated series of intermittent hypoxic exposures on ventilatory response in humans. 査読有り

Katayama, K.,H. Fujita, K. Sato, K. Ishida, K. Iwasaki, and M. Miyamura.

High Alt. Med. Biol. 6 巻頁： 50-59 2005年

*Changes in ventilatory responses to hypercapnia and hypoxia after intermittent hypoxia in humans. 査読有り

Katayama, K.,K. Sato, H. Matsuo, N. Hotta, Z. Sun, K. Ishida, K. Iwasaki, and M. Miyamura.

Respir. Physiol. Neurobiol. 146 巻頁： 55-65 2005年

記述言語：英語掲載種別：研究論文（学術雑誌）

The purpose of this study was to clarify the changes in hypercapnic and hypoxic ventilatory responses (HCVR and HVR) after intermittent hypoxia and following the cessation of hypoxic exposure. Twenty-nine males were assigned to one of four groups, i.e., a hypoxic (EX1-H, n=7) or a control (EX1-C, n=7) group in Experiment 1, and a hypoxic (EX2-H, n=8) or a control (EX2-C, n=7) group in Experiment 2. In each experiment, the hypoxic tent system was utilized for intermittent hypoxia, and the oxygen levels in the tent were maintained at 12.3+/-0.2%. In Experiment 1, the EX1-H group spent 3 h/day in the hypoxic tent for 1 week. HCVR and HVR were determined before and after 1 week of intermittent hypoxia, and again 1 and 2 week after the cessation of hypoxic exposure. In Experiment 2, the subjects in the EX2-H group performed 3 h/day for 2 weeks in intermittent hypoxia. HCVR and HVR tests were carried out before and after intermittent hypoxia, and were repeated again after 2 weeks of the cessation of hypoxic exposure. The slope of the HCVR in the EX1-H group did not show a significant increase after 1 week of intermittent hypoxia, while HCVR in the EX2-H group increased significantly after 2 weeks of intermittent hypoxia. The HCVR intercept was unchanged following 1 or 2 weeks of intermittent hypoxia. There was a significant increase in the slope of the HVR after 1 and 2 weeks of intermittent hypoxia. The increased HCVR and HVR returned to pre-hypoxic levels after 2 weeks of the cessation of hypoxia. These results suggest that 3 h/day for 2 weeks of intermittent hypoxia leads to an increase in central hypercapnic ventilatory chemosensitivity, which is not accompanied by a re-setting of the central chemoreceptors, and that the increased hypercapnic and hypoxic chemosensitivities are restored within 2 weeks after the cessation of hypoxia.

Acceleration with exercise during head-down bed rest preserves upright exercise responses.

Katayama K, Sato K, Akima H, Ishida K, Takada H, Watanabe Y, Iwase M, Miyamura M, Iwase S

Aviation, space, and environmental medicine 75 巻 ( 12 ) 頁： 1029-35 2004年12月

Ventilatory and heart rate responses at the onset of chair rotation in man.

Miyamura M, Ishida K, Katayama K, Shima N, Matsuo H, Sato K

The Japanese journal of physiology 54 巻 ( 5 ) 頁： 499-503 2004年10月

Effect of centrifuge-induced artificial gravity and ergometric exercise on cardiovascular deconditioning, myatrophy, and osteoporosis induced by a -6 degrees head-down bedrest.

Iwase S, Takada H, Watanabe Y, Ishida K, Akima H, Katayama K, Iwase M, Hirayanagi K, Shiozawa T, Hamaoka T, Masuo Y, Custaud MA

Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology 11 巻 ( 2 ) 頁： P243-4 2004年7月

Effect of intermittent hypoxia on oxygen uptake during submaximal exercise in endurance athletes.

Katayama K, Sato K, Matsuo H, Ishida K, Iwasaki K, Miyamura M

European journal of applied physiology 92 巻 ( 1-2 ) 頁： 75-83 2004年6月

Ventilatory and circulatory responses at the onset of voluntary exercise and passive movement in sprinters.

Sato K, Matsuo H, Katayama K, Ishida K, Honda Y, Katsumata K, Miyamura M

European journal of applied physiology 92 巻 ( 1-2 ) 頁： 196-203 2004年6月

Ventilatory and cardiovascular responses to hypercapnia after 20 days of head-down bed rest. 査読有り

Katayama K, Sato K, Akima H, Ishida K, Yanagiya T, Kanehisa H, Fukuoka H, Fukunaga T, Miyamura M

Aviation, space, and environmental medicine 75 巻 ( 4 ) 頁： 312 - 6 2004年4月

Effects of 20 days head-down bed rest on ventilatory and cardiovascular responses to hypercapnia. 査読有り

Katayama, K., K. Sato, H. Akima, K. Ishida, T. Yanagiya, H. Kanehisa, H. Fukuoka, T. Fukunaga, and M. Miyamura.

Aviat. Space Environ. Med. 75 巻頁： 312-316 2004年

Effect of intermittent hypoxia on oxygen uptake during submaximal exercise in endurance athletes. 査読有り

Katayama, K., K. Sato, H. Matsuo, K. Ishida, K. Iwasaki, and M. Miyamura.

Eur. J. Appl. Physiol. 92 巻頁： 75-83 2004年

Effects of intermittent hypoxic training and detraining on ventilatory chemosensitive adaptations in endurance athletes. 査読有り

Katayama, K., K. Sato, H. Matsuo, K. Ishida, S. Mori, and M. Miyamura.

Adv. Exp. Med. Biol. 551 巻頁： 299-304 2004年

Effects of 20 days head-down bed rest on ventilatory and cardiovascular responses to hypercapnia. 査読有り

Katayama, K., K. Sato, H. Akima, K. Ishida, T. Yanagiya, H. Kanehisa, H. Fukuoka, T. Fukunaga, and M. Miyamura.

Aviat. Space Environ. Med. 75 巻頁： 313-316 2004年

Effect of intermittent hypoxia on oxygen uptake during submaximal exercise in endurance athletes. 査読有り

Katayama, K., K. Sato, H. Matsuo, K. Ishida, K. Iwasaki, and M. Miyamura.

Eur. J. Appl. Physiol. 92 巻頁： 75-83 2004年

Effects of intermittent hypoxic training and detraining on ventilatory chemosensitive adaptations in endurance athletes. 査読有り

Katayama, K., K. Sato, H. Matsuo, K. Ishida, S. Mori, and M. Miyamura.

Adv. Exp. Med. Biol. 551 巻頁： 299-304 2004年

Acceleration with exercise during head-down bed rest preserves upright exercise responses. 査読有り

Katayama, K., K. Sato, H. Akima, K. Ishida, H. Takada, Y. Watanabe, M. Iwase, M. Miyamura, and S. Iwase.

Aviat. Space Environ. Med. 75 巻頁： 1029-1035 2004年

Effects of intermittent hypoxic training and detraining on ventilatory chemosensitive adaptations in endurance athletes.

Katayama K, Sato K, Matsuo H, Ishida K, Mori S, Miyamura M

Advances in experimental medicine and biology 551 巻頁： 299-304 2004年

Effect of menstrual cycle and gender on ventilatory and heart rate responses at the onset of exercise.

Matsuo H, Katayama K, Ishida K, Muramatsu T, Miyamura M

European journal of applied physiology 90 巻 ( 1-2 ) 頁： 100-8 2003年9月

Cardiorespiratory responses to hypoxia and hypercapnia at rest in vocalists.

Miyamura M, Ishida K, Katayama K, Sato Y, Morotome Y, Shima N, Matsuo H, Sato K

The Japanese journal of physiology 53 巻 ( 1 ) 頁： 17-24 2003年2月

Intermittent hypoxia improves endurance performance and submaximal exercise efficiency. 査読有り

Katayama, K., H. Matsuo, K. Ishida, S. Mori, and M. Miyamura.

High Alt. Med. Biol. 4 巻頁： 291-304 2003年

Effect of cycling experience and pedal cadence on the near-infrared spectroscopy parameters.

Takaishi T, Ishida K, Katayama K, Yamazaki K, Yamamoto T, Moritani T

Medicine and science in sports and exercise 34 巻 ( 12 ) 頁： 2062-71 2002年12月

Enhanced chemosensitivity after intermittent hypoxic exposure does not affect exercise ventilation at sea level.

Katayama K, Sato Y, Shima N, Qiu JC, Ishida K, Mori S, Miyamura M

European journal of applied physiology 87 巻 ( 2 ) 頁： 187-91 2002年6月

Is man able to breathe once a minute for an hour?: the effect of yoga respiration on blood gases.

Miyamura M, Nishimura K, Ishida K, Katayama K, Shimaoka M, Hiruta S

The Japanese journal of physiology 52 巻 ( 3 ) 頁： 313-6 2002年6月

Changes in blood volume and oxygenation level in a working muscle during a crank cycle.

Takaishi T, Sugiura T, Katayama K, Sato Y, Shima N, Yamamoto T, Moritani T

Medicine and science in sports and exercise 34 巻 ( 3 ) 頁： 520-8; discussion 529 2002年3月

Cross education of muscular strength during unilateral resistance training and detraining.

Shima N, Ishida K, Katayama K, Morotome Y, Sato Y, Miyamura M

European journal of applied physiology 86 巻 ( 4 ) 頁： 287-94 2002年2月

Enhanced chemosensitivity after intermittent hypoxic exposure does not affect exercise ventilation at sea level. 査読有り

Katayama, K., Y. Sato, N. Shima, J. Qiu, K. Ishida, S. Mori, and M. Miyamura.

Eur. J. Appl. Physiol 87 巻頁： 187-191 2002年

記述言語：英語掲載種別：研究論文（学術雑誌）

The purpose of the present study was to test the hypothesis that the ventilatory response to exercise at sea level may increase after intermittent hypoxic exposure for 1 week, accompanied by an increase in hypoxic or hypercapnic ventilatory chemosensitivity. One group of eight subjects (hypoxic group) were decompressed in a chamber to 432 torr (where 1 torr=1.0 mmHg, simulating an altitude of 4,500 m) over a period of 30 min and maintained at that pressure for 1 h daily for 7 days. Oxygen uptake and pulmonary ventilation (V(E)) were determined at 40%, 70%, and 100% of maximal oxygen uptake at sea level before (Pre) and after (Post) 1 week of daily exposures to hypoxia. The hypoxic ventilatory response (HVR) was determined using the isocapnic progressive hypoxic method as an index of ventilatory chemosensitivity to hypoxia, and the hypercapnic ventilatory response (HCVRSB) was measured by means of the single-breath carbon dioxide method as an index of peripheral ventilatory chemosensitivity to hypercapnia. The same parameters were measured in another group of six subjects (control group). In the hypoxic group, resting HVR increased significantly ( P<0.05) after intermittent hypoxia and HCVRSB increased at Post, but the change was not statistically significant ( P=0.07). In contrast, no changes in HVR and HCVRSB were found in the control group. There were no changes in either V(E) or the ventilatory equivalent for oxygen during maximal and submaximal exercise at sea level throughout the experimental period in either group. These results suggest that the changes in resting hypoxic and peripheral hypercapnic chemosensitivities following short-term intermittent hypoxia have little effect on exercise ventilation at sea level.

Effect of intermittent hypoxia on cardiovascular adaptations and response to progressive hypoxia in humans. 査読有り

Katayama, K., N. Shima, Y. Sato, J. Qiu, K. Ishida, S. Mori, and M. Miyamura.

High Alt. Med. Biol. 2 巻頁： 501-508 2001年

記述言語：英語掲載種別：研究論文（学術雑誌）

The aim of the present study was to elucidate (1) the cardiovascular adaptations and response to hypoxic stimuli during short-term intermittent hypoxia and (2) whether the change in cardiovascular response to hypoxia is correlated to the change in hypoxic ventilatory chemosensitivity. Fourteen subjects were decompressed in a chamber to 432 torr, simulating an altitude of 4500 m, over a period of 30 min and were maintained at that pressure for 1 h daily for 7 days. Ventilatory (DeltaV(I)/DeltaSa(O2); Sa(O2) is arterial oxygen saturation), systolic and diastolic blood pressure (DeltaSBP/DeltaSa(O2) and DeltaDBP/DeltaSa(O2)), and heart rate (DeltaHR/DeltaSa(O2)) responses to progressive isocapnic hypoxia were measured before and after intermittent hypoxia. Resting ventilation, SBP, DBP, and HR did not change after intermittent hypoxia. DeltaSBP/DeltaSa(O2) and DeltaDBP/DeltaSa(O2) increased significantly after intermittent hypoxia accompanied by an enhanced DeltaV(I)/DeltaSa(C2), but there was no change in DeltaHR/DeltaSa(C2). There were significant correlations between the change in DeltaV(I)/DeltaSa(O2) and both the changes in DeltaSBP/DeltaSa(O2) and DeltaDBP/DeltaSa(O2) following intermittent hypoxic exposure. These results suggest that short-term intermittent hypoxia leads to the enhanced arterial BP response to hypoxic stimuli in humans, and that the enhanced peripheral chemosensitivity to hypoxia after intermittent hypoxia may play an important role in the increased arterial BP response.

Intermittent hypoxia increases ventilation and SaO2 during hypoxic exercise and hypoxic chemosensitivity. 査読有り

Katayama, K., Y. Sato, Y. Morotome, N. Shima, K. Ishida, S. Mori, and M. Miyamura.

J. Appl. Physiol. 90 巻頁： 1431-1440 2001年

記述言語：英語掲載種別：研究論文（学術雑誌）

The purpose of this study was 1) to test the hypothesis that ventilation and arterial oxygen saturation (Sa(O2)) during acute hypoxia may increase during intermittent hypoxia and remain elevated for a week without hypoxic exposure and 2) to clarify whether the changes in ventilation and Sa(O2) during hypoxic exercise are correlated with the change in hypoxic chemosensitivity. Six subjects were exposed to a simulated altitude of 4,500 m altitude for 7 days (1 h/day). Oxygen uptake (VO2), expired minute ventilation (VE), and Sa(O2) were measured during maximal and submaximal exercise at 432 Torr before (Pre), after intermittent hypoxia (Post), and again after a week at sea level (De). Hypoxic ventilatory response (HVR) was also determined. At both Post and De, significant increases from Pre were found in HVR at rest and in ventilatory equivalent for O2 (VE/VO2) and Sa(O2) during submaximal exercise. There were significant correlations among the changes in HVR at rest and in VE/VO2 and Sa(O2) during hypoxic exercise during intermittent hypoxia. We conclude that 1 wk of daily exposure to 1 h of hypoxia significantly improved oxygenation in exercise during subsequent acute hypoxic exposures up to 1 wk after the conditioning, presumably caused by the enhanced hypoxic ventilatory chemosensitivity.

Ventilatory and circulatory responses at the onset of voluntary exercise and passive movement in children 査読有り

Y Sato, K Katayama, K Ishida, M Miyamura

EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY 83 巻 ( 6 ) 頁： 516 - 523 2000年12月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：SPRINGER-VERLAG

The purpose of this study was to investigate whether or not the ventilatory and circulatory responses at the onset of voluntary exercise and passive movement, especially at the initial stage (phase I), in children are the same as in adults. Ten pre-teenage male children and ten adult men participated in this study. Voluntary exercise and passive movement were performed in a sitting position for about 20 s. Both the exercise and the movement consisted of flexion-extensions of the lower leg from a vertical to horizontal position, either voluntarily or passively, with a frequency of about 60.min(-1). Inspiratory minute ventilation ((V) over dot(I)), tidal volume (V-T), respiratory frequency, partial pressure of end-tidal CO2 and O-2, heart rate (f(c)) and mean blood pressure ((BP) over bar) before, during and after exercise or movement were measured using breath-by-breath and beat-to-beat techniques. Cardiorespiratory responses at the onset of voluntary exercise and passive movement were compared with the relative change (Delta), which was estimated from the value at rest (100%). In the present study, it was found that: (1) the V-I during voluntary exercise were significantly lower in the children, mainly due to lower DeltaV(T); (2) the Deltaf(c) during voluntary exercise was almost the same in both groups, while Deltaf(c) was significantly lower in the children during the last part of passive movement; (3) in the voluntary exercise and passive movement, the (BP) over bar in the children was increased a little or remained close to the value at rest, while it was significantly decreased in the adults. As a result, there were significant differences in Delta(BP) over bar between the two groups during voluntary exercise. These results suggest that the cardiorespiratory responses at the onset of voluntary exercise and passive movement may be modified during the growth process.

Web of Science

Cardiovascular response to hypoxia after endurance training at altitude and sea level and after detraining 査読有り

K Katayama, Y Sato, Y Morotome, N Shima, K Ishida, S Mori, M Miyamura

JOURNAL OF APPLIED PHYSIOLOGY 88 巻 ( 4 ) 頁： 1221 - 1227 2000年4月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：AMER PHYSIOLOGICAL SOC

The pur pose of this study was to elucidate 1) the effects of endurance exercise training during hypoxia or normoxia and of detraining on ventilatory and cardiovascular responses to progressive isocapnic hypoxia and 2) whether the change in the cardiovascular response to hypoxia is correlated to changes in the hypoxic ventilatory response (HVR) after training and detraining. Seven men (altitude group) performed endurance training using a cycle ergometer in a hypobaric chamber of simulated 4,500 m, whereas the other seven men (sea-level group) trained at sea level (K. Katayama, Y. Sate, Y. Morotome, N. Shima, K. Ishida, S. Mori, and M. Miyamura. J. Appl. Physiol. 86: 1805-1811, 1999). The HVR, systolic and diastolic blood pressure responses (Delta SBP/Delta Sa(O2), Delta DBP/Delta Sa(O2)), and heart rate response (Delta HR/Delta Sa(O2) Sa(O2) is arterial oxygen saturation) to progressive isocapnic hypoxia were measured before and after training and during detraining. Delta SBP/Delta Sa(O2) increased significantly in the altitude group and decreased significantly in the sea-level group after training. The changed Delta SBP/Delta Sa(O2) in both groups was restored during 2 wk of detraining, as were the changes in HVR, whereas there were no changes in the Delta DBP/Delta Sa(O2) and Delta HR/Delta Sa(O2) throughout the experimental period. The changes in Delta SBP/Delta Sa(O2)? after training and detraining were significantly correlated with those in HVR. These results suggest that Delta SBP/Delta Sa(O2), to progressive isocapnic hypoxia is variable after endurance training during hypoxia and normoxia and after detraining, as is HVR, but Delta DBP/Delta Sa(O2) and Delta HR/Sa(O2) are not. It also suggests that there is an interaction between the changes in Delta SBP/Delta Sa(O2) and HVR after endurance training or detraining.

Web of Science

Cardiovascular response to isocapnic hypoxia after endurance training at altitude, sea level, and detraining. 査読有り

Katayama, K., Y. Sato, Y. Morotome, N. Shima, K. Ishida, S. Mori, and M. Miyamura

J. Appl. Physiol. 88 巻頁： 1221-1227 2000年

記述言語：英語掲載種別：研究論文（学術雑誌）

The purpose of this study was to elucidate 1) the effects of endurance exercise training during hypoxia or normoxia and of detraining on ventilatory and cardiovascular responses to progressive isocapnic hypoxia and 2) whether the change in the cardiovascular response to hypoxia is correlated to changes in the hypoxic ventilatory response (HVR) after training and detraining. Seven men (altitude group) performed endurance training using a cycle ergometer in a hypobaric chamber of simulated 4,500 m, whereas the other seven men (sea-level group) trained at sea level (K. Katayama, Y. Sato, Y. Morotome, N. Shima, K. Ishida, S. Mori, and M. Miyamura. J. Appl. Physiol. 86: 1805-1811, 1999). The HVR, systolic and diastolic blood pressure responses (DeltaSBP/DeltaSa(O(2)), DeltaDBP/DeltaSa(O(2))), and heart rate response (DeltaHR/DeltaSa(O(2)); Sa(O(2)) is arterial oxygen saturation) to progressive isocapnic hypoxia were measured before and after training and during detraining. DeltaSBP/DeltaSa(O(2)) increased significantly in the altitude group and decreased significantly in the sea-level group after training. The changed DeltaSBP/DeltaSa(O(2)) in both groups was restored during 2 wk of detraining, as were the changes in HVR, whereas there were no changes in the DeltaDBP/DeltaSa(O(2)) and DeltaHR/DeltaSa(O(2)) throughout the experimental period. The changes in DeltaSBP/DeltaSa(O(2)) after training and detraining were significantly correlated with those in HVR. These results suggest that DeltaSBP/DeltaSa(O(2)) to progressive isocapnic hypoxia is variable after endurance training during hypoxia and normoxia and after detraining, as is HVR, but DeltaDBP/DeltaSa(O(2)) and DeltaHR/DeltaSa(O(2)) are not. It also suggests that there is an interaction between the changes in DeltaSBP/DeltaSa(O(2)) and HVR after endurance training or detraining.

Ventilatory chemosensitive adaptations to intermittent hypoxic exposure with endurance training and detraining 査読有り

K Katayama, Y Sato, Y Morotome, N Shima, K Ishida, S Mori, M Miyamura

JOURNAL OF APPLIED PHYSIOLOGY 86 巻 ( 6 ) 頁： 1805 - 1811 1999年6月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：AMER PHYSIOLOGICAL SOC

The present study was performed to clarify the effects of intermittent exposure to an altitude of 4,500 m with endurance training and detraining on ventilatory chemosensitivity. Seven subjects (sea-level group) trained at sea level at 70% maximal oxygen uptake ((V) over doto(2max)) for 30 min/day, 5 days/wk for 2 wk, whereas the other seven subjects (altitude group) trained at the same relative intensity (70% altitude (V) over doto(2max)) in a hypobaric chamber. (V) over doto(2max) hypoxic ventilatory response (HVR), and hypercapnic ventilatory response, as an index of central hypercapnic chemosensitivity (HCVR) and as an index of peripheral chemosensitivity (HCVRSB), were measured. In both groups (V) over doto(2max) increased significantly after training, and a significant loss of (V) over doto(2max) occurred during 2 wk of detraining. HVR tended to increase in the altitude group but not significantly, whereas it decreased significantly in the sea-level group after training. HCVR and HCVRSB did not change in each group. After detraining, HVR returned to the pretraining level in both groups. These results suggest that ventilatory chemosensitivity to hypoxia is more variable by endurance training and detraining than that to hypercapnia.

Web of Science

Ventilatory chemosensitive adaptations to intermittent hypoxic exposure with endurance training and detraining. 査読有り

Katayama, K., Y. Sato, Y. Morotome, N. Shima, K. Ishida, S. Mori, and M. Miyamura.

J. Appl. Physiol 86 巻頁： 1805-1811 1999年

記述言語：英語掲載種別：研究論文（学術雑誌）

The present study was performed to clarify the effects of intermittent exposure to an altitude of 4,500 m with endurance training and detraining on ventilatory chemosensitivity. Seven subjects (sea-level group) trained at sea level at 70% maximal oxygen uptake (VO2 max) for 30 min/day, 5 days/wk for 2 wk, whereas the other seven subjects (altitude group) trained at the same relative intensity (70% altitude VO2 max) in a hypobaric chamber. VO2 max, hypoxic ventilatory response (HVR), and hypercapnic ventilatory response, as an index of central hypercapnic chemosensitivity (HCVR) and as an index of peripheral chemosensitivity (HCVRSB), were measured. In both groups VO2 max increased significantly after training, and a significant loss of VO2 max occurred during 2 wk of detraining. HVR tended to increase in the altitude group but not significantly, whereas it decreased significantly in the sea-level group after training. HCVR and HCVRSB did not change in each group. After detraining, HVR returned to the pretraining level in both groups. These results suggest that ventilatory chemosensitivity to hypoxia is more variable by endurance training and detraining than that to hypercapnia.

Effects of maximal interval training on arterial oxygen desaturation and ventilation during heavy exercise

Motohiko Miyachi, Keisho Katayama

Japanese Journal of Physiology 49 巻 ( 5 ) 頁： 401 - 407 1999年

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：The Physiological Society of Japan

The purpose of the present study was to clarify longitudinally the effects of exercise training on arterial O2 saturation (Sa(O)2) and ventilation during heavy exercise. A group of six subjects (training group) volunteered to train four times a week for 12 weeks. Each training session consisted of five 3-min periods of exercise on a cycle ergometer at a power output of 100% maximal O2 uptake (V̇O(2 max)), interspersed with 2 min recovery period cycling at 50% V̇O(2 max). During the training, V̇O(2 max), Sa(O)2, the ventilatory equivalent for oxygen (V̇E/V̇O2), and the end- tidal partial pressure of O2 (PET(O)2) during heavy exercise were measured periodically. The same parameters were measured simultaneously in another group of five subjects (control group) who led normal lives. Maximal interval training increases V̇O(2 max), with little change in V̇E(max) and pulmonary functions at rest. The training decreased PET(O)2, V̇E/V̇O2, and Sa(O)2 during heavy exercise. Sa(O)2 is significantly related to V̇E/V̇O2 (r2 = 0.49). These results suggest that less hyperventilatory response to exercise occurs with progress in physical training because the adaptability of ventilatory capacity is less than that of aerobic work capacity, which half induces arterial O2 desaturation during heavy exercise. PET(O)2 as well as V̇E/V̇O2 and V̇O(2 max) did not change anymore after the 6th week, nevertheless Sa(O)2 kept decreasing up to the last 2 weeks. In addition, when the Sa(O)2-V̇E/V̇O2 plot was compared between the two groups, the regression line of the training group was steeper than that of the control groups
i.e., compared at a lower level of V̇E/V̇O2 (~30 ml · ml-1), the Sa(O)2 of the trained subjects exercising at a higher V̇O2 level was lower than that of the control subjects. Predominance of less hyperventilation and another factor, increased A-aDO2, in the genesis of arterial hypoxemia and O2 desaturation may be dependent upon V̇O2 levels in heavy exercise and the state of training.

DOI： 10.2170/jjphysiol.49.401

Scopus

PubMed

The effects of intermittent exposure to hypoxia during endurance exercise training on the ventilatory responses to hypoxia and hypercapnia in humans 査読有り

Keisho Katayama, Yasutake Sato, Koji Ishida, Shigeo Mori, Miharu Miyamura

European Journal of Applied Physiology and Occupational Physiology 78 巻 ( 3 ) 頁： 189 - 194 1998年8月

記述言語：英語掲載種別：研究論文（学術雑誌）

The present study was performed to investigate the effects of a combination of intermittent exposure to hypoxia during exercise training for short periods on ventilatory responses to hypoxia and hypercapnia (HVR and HCVR respectively) in humans. In a hypobaric chamber at a simulated altitude of 4500 m (barometric pressure 432 mmHg), seven subjects (training group) performed exercise training for 6 consecutive days (30 min·day-1), while six subjects (control group) were inactive during the same period. The HVR, HCVR and maximal oxygen uptake (V̇O(2max)) for each subject were measured at sea level before (pre) and after exposure to intermittent hypoxia. The post exposure test was carried out twice, i.e. on the 1st day and 1 week post exposure. It was found that HVR, as an index of peripheral chemosensitivity to hypoxia, was increased significantly (P &lt
0.05) in the control group after intermittent exposure to hypoxia. In contrast, there was no significant increase in HVR in the training group after exposure. The HCVR in both groups was not changed by intermittent exposure to hypoxia, while V̇O(2max) increased significantly in the training group. These results would suggest that endurance training during intermittent exposure to hypoxia depresses the increment of chemosensitivity to hypoxia, and that intermittent exposure to hypoxia in the presence or absence of exercise training does not induce an increase in the chemosensitivity to hypercapnia in humans.

DOI： 10.1007/s004210050406

Scopus

PubMed

The effects of intermittent exposure to hypoxia during endurance exercise training on the ventilatory responses to hypoxia and hypercapnia in humans. 査読有り

Katayama, K., Y. Sato, K. Ishida, S. Mori, and M. Miyamura.

Eur. J. Appl. Physiol. 78 巻頁： 189-194 1998年

記述言語：英語掲載種別：研究論文（学術雑誌）

The present study was performed to investigate the effects of a combination of intermittent exposure to hypoxia during exercise training for short periods on ventilatory responses to hypoxia and hypercapnia (HVR and HCVR respectively) in humans. In a hypobaric chamber at a simulated altitude of 4,500 m (barometric pressure 432 mmHg), seven subjects (training group) performed exercise training for 6 consecutive days (30 min x day(-1)), while six subjects (control group) were inactive during the same period. The HVR, HCVR and maximal oxygen uptake (VO2max) for each subject were measured at sea level before (pre) and after exposure to intermittent hypoxia. The post exposure test was carried out twice, i.e. on the 1st day and 1 week post exposure. It was found that HVR, as an index of peripheral chemosensitivity to hypoxia, was increased significantly (P < 0.05) in the control group after intermittent exposure to hypoxia. In contrast, there was no significant increase in HVR in the training group after exposure. The HCVR in both groups was not changed by intermittent exposure to hypoxia, while VO2max increased significantly in the training group. These results would suggest that endurance training during intermittent exposure to hypoxia depresses the increment of chemosensitivity to hypoxia, and that intermittent exposure to hypoxia in the presence or absence of exercise training does not induce an increase in the chemosensitivity to hypercapnia in humans.

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