Updated on 2022/03/08

写真a

 
KATAYAMA, Keisho
 
Organization
Research Center of Health, Physical Fitness and Sports Division of the Science of Physical Fitness and Sports Professor
Graduate School
Graduate School of Medicine
Title
Professor

Degree 3

  1. Ph.D. ( 2000.8   Nagoya University ) 

  2. 修士(健康教育学) ( 1997.3   筑波大学 ) 

  3. 学士(健康体育学) ( 1995.3   川崎医療福祉大学 ) 

Research Interests 1

  1. Exercise Physiology

Research Areas 2

  1. Others / Others  / Sports Science(Exercise Physiology)

  2. Life Science / Sports sciences

Current Research Project and SDGs 2

  1. 呼吸筋活動が運動時の循環調節に及ぼす影響

  2. Physiological adaptations to hypoxia (altitude or hypoxic training, respiratory and cardiovascular resposes to exercise)

Research History 8

  1. University of Texas at Arlington   Department of Kinesiology   Visiting Professor

    2017.9 - 2017.12

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    Country:United States

  2. Nagoya University   Professor

    2017.4

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    Country:Japan

  3. Nagoya University   Graduate School of Medicine   Professor

    2017.4

  4. Nagoya University   Associate professor

    2008.4 - 2017.3

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    Country:Japan

  5. University of Wisconsin at Madison   Department of Population Health Sciences, The John Rankin Laboratory of Pulmonary Medicine   Visiting Assistant Professor

    2005.9 - 2006.8

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    Country:United States

  6. Nagoya University   Lecturer

    2004.4 - 2008.3

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    Country:Japan

  7. Nagoya University   Assistant

    2001.10 - 2004.3

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    Country:Japan

  8. Japan Society for Promotion of Science

    2001.4 - 2001.9

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    Country:Japan

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Education 3

  1. Nagoya University   Graduate School, Division of Medicine

    1997.4 - 2000.7

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    Country: Japan

  2. University of Tsukuba   Graduate School, Division of Physical Education

    1995.4 - 1997.3

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    Country: Japan

  3. Kawasaki University of Medical Welfare   Department of Health and Sports Science,

    1991.4 - 1995.3

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    Country: Japan

Professional Memberships 4

  1. 日本体力医学会

  2. 日本体育学会

  3. American College of Sports Medicine

  4. International Society of Mountain Medicine

Committee Memberships 4

  1. 日本体力医学会・東海地方会   理事  

    2020.3   

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    Committee type:Academic society

  2. 日本体力医学会   利益相反委員会委員  

    2016.4 - 2018.3   

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    Committee type:Academic society

  3. 日本体力医学会   JPFSM投稿・引用促進WG委員  

    2015.10 - 2017.9   

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    Committee type:Academic society

  4. 日本体力医学会   評議員  

    2008.9   

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    Committee type:Academic society

Awards 4

  1. 第22回 日本体力医学会東海地方会学術集会 学術奨励賞

    2018.3   日本体力医学会・東海地方会  

  2. 第21回 日本体力医学会東海地方会学術集会 学術奨励賞

    2017.3   日本体力医学会・東海地方会  

  3. 第15回 日本体力医学会東海地方会学術集会 学術奨励賞

    2011.3   日本体力医学会・東海地方会  

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    Country:Japan

  4. 平成21年度(第2回)呼吸研究会若手奨励賞

    2009.9   呼吸研究会  

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    Country:Japan

 

Papers 117

  1. Cerebral blood velocity and arterial pressure at the onset of exercise: potential influence of the cardiopulmonary baroreflex.

    Ogoh S, Saito S, Watanabe H, Katayama K

    Clinical autonomic research : official journal of the Clinical Autonomic Research Society     2022.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s10286-022-00855-4

    PubMed

  2. Relationship between respiratory muscle endurance and dyspnea during high-intensity exercise in trained distance runners.

    Mizuno S, Suzuki Y, Goto K, Takao K, Sumi D, Ishida K, Mizuno F, Katayama K

    Respiratory physiology & neurobiology   Vol. 296   page: 103812   2022.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.resp.2021.103812

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  3. Effect of Moderate- or High-Intensity Inspiratory Muscle Strength Training on Maximal Inspiratory Mouth Pressure and Swimming Performance in Highly Trained Competitive Swimmers.

    Ohya T, Kusanagi K, Koizumi J, Ando R, Katayama K, Suzuki Y

    International journal of sports physiology and performance   Vol. 17 ( 3 ) page: 343 - 349   2021.10

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1123/ijspp.2021-0119

    PubMed

  4. Respiratory modulation of sympathetic vasomotor outflow during graded leg cycling Reviewed International coauthorship

    Katayama K., Dominelli P.B., Foster G.., Kipp S., Leahy M.G., Ishida K., and Sheel A.W.

    Journal of Applied Physiology   Vol. 131   page: 858 - 867   2021.6

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1152/japplphysiol.00118.2021.

  5. Age and sex differences in blood pressure responses during hyperpnoea.

    Shimizu K, Shiozawa K, Ishida K, Saito M, Mizuno S, Akima H, Katayama K

    Experimental physiology   Vol. 106 ( 3 ) page: 736 - 747   2021.3

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1113/EP089171

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  6. Effects of sex and age on blood pressure response during voluntary normocapnic hyperpnea(和訳中)

    Shimizu Kaori, Shiozawa Kana, Saito Mitsuru, Ishida Koji, Mizuno Sahiro, Akima Hiroshi, Katayama Keisho

    The Journal of Physical Fitness and Sports Medicine   Vol. 9 ( 6 ) page: 290 - 290   2020.11

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:(一社)日本体力医学会  

  7. Sex differences in blood flow distribution during dynamic leg exercise with increased inspiratory muscle work(和訳中)

    Shiozawa Kana, Shimizu Kaori, Saito Mitsuru, Ishida Koji, Mizuno Sahiro, Katayama Keisho

    The Journal of Physical Fitness and Sports Medicine   Vol. 9 ( 6 ) page: 294 - 294   2020.11

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:(一社)日本体力医学会  

  8. Blood pressure and limb blood flow responses during hyperpnoea are not affected by menstrual cycle phase in young women. Reviewed

    Shimizu K, Shiozawa K, Ishida K, Saito M, Mizuno S, Akima H, Katayama K

    Respiratory Physiology & Neurobiology   Vol. 275   page: 103387   2020.4

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    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.resp.2020.103387

    PubMed

  9. The interactive effects of acute exercise and hypoxia on cognitive performance: A narrative review. International coauthorship

    Ando S, Komiyama T, Sudo M, Higaki Y, Ishida K, Costello JT, Katayama K

    Scandinavian Journal of Medicine & Science in Sports   Vol. 30 ( 3 ) page: 384-398   2020.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/sms.13573

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  10. Effect of inspiratory resistive training on diaphragm shear modulus and accessory inspiratory muscle activation. Reviewed

    Ando R, Ohya T, Kusanagi K, Koizumi J, Ohnuma H, Katayama K, Suzuki Y

    Applied Physiology, Nutrition, and Metabolism     2020.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1139/apnm-2019-0906

    PubMed

  11. The hyperpnoea of exercise in health: Respiratory influences on neurovascular control Invited Reviewed International coauthorship

    Sheel A.W., Taylor J.L., and Katayama K.

    Experimental Physiology     2020.2

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    Authorship:Last author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1113/EP088103

  12. Muscle deoxygenation and neuromuscular activation in synergistic muscles during intermittent exercise under hypoxic conditions. Reviewed

    Yoshiko A, Katayama K, Ishida K, Ando R, Koike T, Oshida Y, Akima H

    Scientific Reports   Vol. 10 ( 1 ) page: 295   2020.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41598-019-57099-y

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  13. Muscle pump-induced inhibition of sympathetic vasomotor outflow during low-intensity leg cycling is attenuated by muscle metaboreflex activation. Reviewed

    Katayama K, Barbosa TC, Kaur J, Young BE, Nandadeva D, Ogoh S, Fadel PJ

    Journal of Applied Physiology (Bethesda, Md. : 1985)   Vol. 128 ( 1 ) page: 1-7   2020.1

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1152/japplphysiol.00639.2019

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  14. 6週間の呼吸筋トレーニングがエリート水泳選手の横隔膜と呼吸補助筋の機能に及ぼす効果

    安藤 良介, 大家 利之, 草薙 健太, 小泉 潤, 大沼 勇人, 片山 敬章, 鈴木 康弘

    Journal of Training Science for Exercise and Sport   Vol. 31 ( 4 ) page: 231 - 231   2020.1

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    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:日本トレーニング科学会  

  15. 認知課題の違いがデュアルタスク遂行能力に及ぼす影響(Effect of different cognitive tasks on dual-task performance)

    Zhang Luyu, Sudo Mizuki, Ando Soichi, Katayama Keisho, Ishida Koji

    The Journal of Physical Fitness and Sports Medicine   Vol. 8 ( 6 ) page: 272 - 272   2019.11

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:(一社)日本体力医学会  

  16. 運動-認知二重課題開始時の呼吸循環応答(Cardio-respiratory responses at the onset of motor-cognitive dual-task)

    Ishida Koji, Zhang Luyu, Sudo Mizuki, Ando Soichi, Katayama Keisho

    The Journal of Physical Fitness and Sports Medicine   Vol. 8 ( 6 ) page: 299 - 299   2019.11

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:(一社)日本体力医学会  

  17. Effects of respiratory muscle endurance training in hypoxia on running performance. Reviewed

    Katayama K, Goto K, Ohya T, Iwamoto E, Takao K, Kasai N, Sumi D, Mori H, Ishida K, Shimizu K, Shiozawa K, Suzuki Y

    Medicine and Science in Sports and Exercise   Vol. 51 ( 7 ) page: 1477-1486   2019.7

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1249/MSS.0000000000001929

    PubMed

  18. Muscle sympathetic nerve activity during exercise.

    Katayama K, Saito M

    The journal of physiological sciences : JPS   Vol. 69 ( 4 ) page: 589-598   2019.7

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s12576-019-00669-6

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  19. Effect of Increased Respiratory Muscle Activation on Blood Flow to Inactive and Active Limb Muscles

    Shiozawa Kana, Goto Kanako, Shimizu Kaori, Saito Mitsuru, Ishida Koji, Zhang Luyu, Sheel William, Katayama Keisho

    MEDICINE AND SCIENCE IN SPORTS AND EXERCISE   Vol. 51 ( 6 ) page: 488-488   2019.6

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    Language:English   Publishing type:Research paper (scientific journal)  

  20. Inspiratory Muscle Strength And Diaphragm Thickness In Elderly Women

    Shimizu Kaori, Shiozawa Kana, Watanabe Kohei, Saito Mitsuru, Ishida Koji, Akima Hiroshi, Katayama Keisho

    MEDICINE AND SCIENCE IN SPORTS AND EXERCISE   Vol. 51 ( 6 ) page: 655-655   2019.6

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    Language:English   Publishing type:Research paper (scientific journal)  

  21. Work of breathing influences muscle sympathetic nerve activity during semi-recumbent cycle exercise.

    Dominelli PB, Katayama K, Vermeulen TD, Stuckless TJR, Brown CV, Foster GE, Sheel AW

    Acta physiologica (Oxford, England)   Vol. 225 ( 4 ) page: e13212   2019.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/apha.13212

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  22. Effect of increased inspiratory muscle work on blood flow to inactive and active limbs during submaximal dynamic exercise.

    Katayama K, Goto K, Shimizu K, Saito M, Ishida K, Zhang L, Shiozawa K, Sheel AW

    Experimental physiology   Vol. 104 ( 2 ) page: 180-188   2019.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1113/EP087380

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  23. Neuromuscular activation of the knee and hip extensor muscles during high-intensity interval and moderate-intensity constant cycling.

    Ando R, Kondo S, Katayama K, Ishida K, Akima H

    Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology   Vol. 44   page: 64-69   2019.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jelekin.2018.11.012

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  24. Acute reduction in posterior cerebral blood flow following isometric handgrip exercise is augmented by lower body negative pressure.

    Washio T, Vranish JR, Kaur J, Young BE, Katayama K, Fadel PJ, Ogoh S

    Physiological reports   Vol. 6 ( 20 ) page: e13886   2018.10

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.14814/phy2.13886

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  25. High-intensity muscle metaboreflex activation attenuates cardiopulmonary baroreflex-mediated inhibition of muscle sympathetic nerve activity

    Katayama Keisho, Kaur Jasdeep, Young Benjamin E., Barbosa Thales C., Ogoh Shigehiko, Fadel Paul J.

    JOURNAL OF APPLIED PHYSIOLOGY   Vol. 125 ( 3 ) page: 812-819   2018.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1152/japplphysiol.00161.2018

    Web of Science

  26. Diaphragmatic shear modulus at various submaximal inspiratory mouth pressure levels

    Chino Kentaro, Ohya Toshiyuki, Katayama Keisho, Suzuki Yasuhiro

    RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY   Vol. 252   page: 52-57   2018.6

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.resp.2018.03.009

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  27. Blunted Sympathetic Vasomotor Outflow To Inspiratory Resistive Breathing During Exercise In Women Compared to Men

    Katayama Keisho, Smith Joshua R, Goto Kanako, Shimizu Kaori, Saito Mitsuru, Ishida Koji, Koike Teruhiko, Iwase Satoshi, Harms Craig A

    MEDICINE AND SCIENCE IN SPORTS AND EXERCISE   Vol. 50 ( 5 ) page: 284-285   2018.5

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  28. Elevated sympathetic vasomotor outflow in response to increased inspiratory muscle activity during exercise is less in young women compared with men

    Katayama Keisho, Smith Joshua R., Goto Kanako, Shimizu Kaori, Saito Mitsuru, Ishida Koji, Koike Teruhiko, Iwase Satoshi, Harms Craig A.

    EXPERIMENTAL PHYSIOLOGY   Vol. 103 ( 4 ) page: 570-580   2018.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1113/EP086817

    Web of Science

  29. Blood pressure response during normocapnic hyperpnoea is blunted in young women compared to men

    Shimizu Kaori, Goto Kanako, Ishida Koji, Saito Mitsuru, Akima Hiroshi, Katayama Keisho

    RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY   Vol. 247   page: 52-56   2018.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.resp.2017.08.014

    Web of Science

  30. Cognitive function during exercise under severe hypoxia

    Komiyama Takaaki, Katayama Keisho, Sudo Mizuki, Ishida Koji, Higaki Yasuki, Ando Soichi

    SCIENTIFIC REPORTS   Vol. 7   2017.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41598-017-10332-y

    Web of Science

  31. Blood Pressure Response During Hyperpnoea Is Lower in Women Compared with Men

    Shimizu Kaori, Katayama Keisho, Goto Kanako, Ishida Koji, Akima Hiroshi

    MEDICINE AND SCIENCE IN SPORTS AND EXERCISE   Vol. 49 ( 5 ) page: 797-797   2017.5

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1249/01.mss.0000519131.71355.f8

    Web of Science

  32. Respiratory Muscle Endurance And Cardiovascular Response To Hyperpnoea After Respiratory Muscle Training In Hypoxia

    Katayama Keisho, Iwamoto Erika, Ohya Toshiyuki, Goto Kazushige, Takao Kenji, Kasai Nobukazu, Sumi Daichi, Ishida Koji, Suzuki Yasuhiro

    MEDICINE AND SCIENCE IN SPORTS AND EXERCISE   Vol. 49 ( 5 ) page: 796-796   2017.5

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1249/01.mss.0000519128.48485.95

    Web of Science

  33. Neuromuscular activity of quadriceps femoris during cycling with high-intensity interval exercise and constant load exercise

    AKIMA Hiroshi, ISHIDA Koji, KATAYAMA Keisho, ANDO Ryosuke, KONDO Shohei

      Vol. 40 ( 1 ) page: 21 - 27   2017

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.18999/njhpfs.40.1.21

    CiNii Books

    Other Link: http://hdl.handle.net/2237/26898

  34. Blunted blood pressure response during hyperpnoea in endurance runners.

    Itoh Y, Katayama K, Iwamoto E, Goto K, Suzuki Y, Ohya T, Takao K, Ishida K

    Respiratory physiology & neurobiology   Vol. 230   page: 22-8   2016.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.resp.2016.04.010

    PubMed

  35. Reduction In Oxygen Delivery Under Severe Hypoxia Affects Cognitive Function During Moderate Exercise: 1537 Board #190 June 2, 9: 00 AM - 10: 30 AM. Reviewed

    Komiyama T, Katayama K, Sudo M, Ishida K, Higaki Y, Ando S

    Medicine and science in sports and exercise   Vol. 48 ( 5 Suppl 1 ) page: 419   2016.5

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1249/01.mss.0000486262.72930.24

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  36. Hypoxia attenuates cardiopulmonary reflex control of sympathetic nerve activity during mild dynamic leg exercise.

    Katayama K, Ishida K, Saito M, Koike T, Ogoh S

    Experimental physiology   Vol. 101 ( 3 ) page: 377-86   2016.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1113/EP085632

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  37. Responses of sex steroid hormones to different intensities of exercise in endurance athletes.

    Sato K, Iemitsu M, Katayama K, Ishida K, Kanao Y, Saito M

    Experimental physiology   Vol. 101 ( 1 ) page: 168-75   2016.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1113/EP085361

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  38. Hypoxia exaggerates inspiratory accessory muscle deoxygenation during hyperpnoea. Reviewed

    Katayama K., Suzuki Y., Hoshikawa M., Ohya T., Oriishi M., Itoh Y., and Ishida K.

    Respir. Physiol. Neurobiol.   Vol. 211   page: 1-18   2015.6

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.resp.2015.02.005

  39. Exercise intensity modulates brachial artery retrograde blood flow and shear rate during leg cycling in hypoxia. Reviewed

    Iwamoto E., Katayama K., and Ishida K.

    Physiol. Rep.   Vol. 3   page: e12423   2015.6

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  40. Exercise intensity modulates brachial artery retrograde blood flow and shear rate during leg cycling in hypoxia.

    Iwamoto E, Katayama K, Ishida K

    Physiological reports   Vol. 3 ( 6 )   2015.6

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.14814/phy2.12423

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  41. Sympathetic vasomotor outflow and blood pressure increase during exercise with expiratory resistance. Reviewed

    Katayama K., Itoh Y., Saito M., Koike T., and Ishida K.

    Physiol. Rep.   Vol. 3   page: e12421   2015.5

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  42. Sympathetic vasomotor outflow and blood pressure increase during exercise with expiratory resistance.

    Katayama K, Itoh Y, Saito M, Koike T, Ishida K

    Physiological reports   Vol. 3 ( 5 )   2015.5

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.14814/phy2.12421

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  43. Suitability of modified tandem-bicycle ergometer. Reviewed

    Onodera S., Yoshioka A., Yamaguchi H., Matsumoto N., Nishimura K., Kawano H., Saito T., Arakane K., Hayashi S., Takagi Y., Wada T., Murata M., Seki K. Nose Y., Raum B. W., Katayama K., and Ogita F.

    J. Phy. Fit. Sports Med.   Vol. 4   page: 249-251   2015

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  44. Sympathetic vasomotor outflow and blood pressure increase during exercise with expiratory resistance. Reviewed

    Katayama K., Itoh Y., Saito M., Koike T., and Ishida K.

    Physiol. Rep.   Vol. 3   page: e12421   2015

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  45. Hypoxia exaggerates inspiratory accessory muscle deoxygenation during hyperpnoea. Reviewed

    Katayama K., Suzuki Y., Hoshikawa M., Ohya T., Oriishi M., Itoh Y., and Ishida K.

    Respir. Physiol. Neurobiol.   Vol. 211   page: 1-8   2015

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  46. Enhanced muscle pump during mild dynamic leg exercise inhibits sympathetic vasomotor outflow.

    Katayama K, Ishida K, Saito M, Koike T, Hirasawa A, Ogoh S

    Physiological reports   Vol. 2 ( 7 )   2014.7

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.14814/phy2.12070

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  47. Enhanced muscle pump during mild dynamic leg exercise inhibits sympathetic vasomotor outflow Reviewed

    Katayama K., Ishida K., Saito M., Koike T., Hirasawa A., and Ogoh S.

    Physiol Rep   Vol. 2 ( 7 ) page: e12070   2014

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  48. Flow-mediated dilation in the inactive limb following acute hypoxic exercise. Reviewed

    Katayama K., Yamashita S., Iwamoto E., and Ishida K.

    Clin. Physiol. Func. Imaging.     2014

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/cpf.12194

  49. Retrograde blood flow in the inactive limb is enhanced during constant-load leg cycling in hypoxia.

    Iwamoto E, Katayama K, Yamashita S, Oshida Y, Ishida K

    European journal of applied physiology   Vol. 113 ( 10 ) page: 2565-75   2013.10

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00421-013-2694-8

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  50. Hypoxic effects on sympathetic vasomotor outflow and blood pressure during exercise with inspiratory resistance.

    Katayama K, Yamashita S, Ishida K, Iwamoto E, Koike T, Saito M

    American journal of physiology. Regulatory, integrative and comparative physiology   Vol. 304 ( 5 ) page: R374-82   2013.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1152/ajpregu.00489.2012

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  51. The effect of acute exercise in hypoxia on flow-mediated vasodilation.

    Katayama K, Fujita O, Iemitsu M, Kawano H, Iwamoto E, Saito M, Ishida K

    European journal of applied physiology   Vol. 113 ( 2 ) page: 349-57   2013.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00421-012-2442-5

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  52. Hypoxic effects on sympathetic vasomotor outflow and blood pressure during exercise with inspiratory resistance Reviewed

    Katayama K., Yamashita S., Ishida K., Iwamoto E., Koike T., and Saito M.

    Am. J. Appl. Physiol. Regul. Integr. Physiol.   Vol. 304   page: R374-R382   2013

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  53. The effect of acute exercise in hypoxia on flow-mediated vasodilation Reviewed

    Katayama K., Fujita O., Iemitsu M., Kawano H., Iwamoto E., Saito M., and Ishida K

    Eur. J. Appl. Physiol.   Vol. 113   page: 349-357   2013

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  54. 04生-29-口-14 持久能鍛錬者と非鍛錬者の異なる運動負荷における性ホルモン濃度変化の比較(04 運動生理学,一般研究発表抄録)

    佐藤 幸治, 家光 素行, 片山 敬章, 石田 浩司, 金尾 洋治, 斉藤 満

    日本体育学会大会予稿集   Vol. 64   page: 165 - 165   2013

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    DOI: 10.20693/jspehss.64.165_1

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  55. The effect of acute exercise in hypoxia on flow-mediated vasodilation.

    Katayama K, Fujita O, Iemitsu M, Kawano H, Iwamoto E, Saito M, Ishida K

    Eur J Appl Physiol   Vol. 9   page: 47   2012.6

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  56. Hypoxia augments oscillatory blood flow in brachial artery during leg cycling.

    Iwamoto E, Katayama K, Oshida Y, Ishida K

    Medicine and science in sports and exercise   Vol. 44 ( 6 ) page: 1035-42   2012.6

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    DOI: 10.1249/MSS.0b013e31824294f9

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  57. Inspiratory muscle fatigue increases sympathetic vasomotor outflow and blood pressure during submaximal exercise.

    Katayama K, Iwamoto E, Ishida K, Koike T, Saito M

    American journal of physiology. Regulatory, integrative and comparative physiology   Vol. 302 ( 10 ) page: R1167-75   2012.5

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    DOI: 10.1152/ajpregu.00006.2012

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  58. Inspiratory muscle fatigue increases sympathetic vasomotor outflow and blood pressure during submaximal exercise Reviewed

    Katayama K., Iwamoto E., Ishida K., Koike T., and Saito M.

    Am. J. Physiol. Regul. Integr. Comp. Physiol.   Vol. 302   page: R1167-R1175   2012

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  59. Hypoxia augments muscle sympathetic neural response to leg cycling.

    Katayama K, Ishida K, Iwamoto E, Iemitsu M, Koike T, Saito M

    American journal of physiology. Regulatory, integrative and comparative physiology   Vol. 301 ( 2 ) page: R456-64   2011.8

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    DOI: 10.1152/ajpregu.00119.2011

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  60. Hypoxia augments muscle sympathetic neural response to leg cycling Reviewed

    Katayama K, Ishida K, Iwamoto E, Iemitsu M, and Saito M.

      Vol. 301   page: R456-R464   2011

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  61. The effect of intense interval cycle-training on unloading-induced dysfunction and atrophy in the human calf muscle.

    Hotta N, Ishida K, Sato K, Koike T, Katayama K, Akima H

    Journal of physiological anthropology   Vol. 30 ( 1 ) page: 29 - 35   2011

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    DOI: 10.2114/jpa2.30.29

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  62. Aerobic exercise capacity and muscle volume after lower limb suspension with exercise countermeasure.

    Sato K, Katayama K, Hotta N, Ishida K, Akima H

    Aviation, space, and environmental medicine   Vol. 81 ( 12 ) page: 1085-91   2010.12

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    DOI: 10.3357/asem.2724.2010

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  63. Muscle deoxygenation during sustained and intermittent isometric exercise in hypoxia.

    Katayama K, Yoshitake Y, Watanabe K, Akima H, Ishida K

    Medicine and science in sports and exercise   Vol. 42 ( 7 ) page: 1269-78   2010.7

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    DOI: 10.1249/MSS.0b013e3181cae12f

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  64. Substrate utilization during exercise and recovery at moderate altitude.

    Katayama K, Goto K, Ishida K, Ogita F

    Metabolism: clinical and experimental   Vol. 59 ( 7 ) page: 959-66   2010.7

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    DOI: 10.1016/j.metabol.2009.10.017

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  65. Substrate utilization during exercise and recovery at moderate altitude Reviewed

    Katayama, K., K. Goto, K. Ishida, and F. Ogita

    Metabolism   Vol. 59   page: 959-966   2010

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  66. Muscle deoxygenation during sustained and intermittent isometric exercise in hypoxia Reviewed

    Katayama, K., Y. Yoshitake, K. Watanabe, H. Akima, and K. Ishida

    Med. Sci. Sports Exerc.   Vol. 42   page: 1269-1278   2010

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  67. Electromyographic analysis of hip adductor muscles during incremental fatiguing pedaling exercise.

    Watanabe K, Katayama K, Ishida K, Akima H

    European journal of applied physiology   Vol. 106 ( 6 ) page: 815-25   2009.8

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    DOI: 10.1007/s00421-009-1086-6

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  68. Effect of Intensive Interval Training during Unloading on Muscle Deoxygenation Kinetics Reviewed

    Y. Furuichi, K. Masuda, H. Takakura, N. Hotta, K. Ishida, K. Katayama, S. Iwase, H. Akima

    INTERNATIONAL JOURNAL OF SPORTS MEDICINE   Vol. 30 ( 8 ) page: 563 - 568   2009.8

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    The present study investigated the effects of intensive interval training during 20-day of unloading on local muscle oxygenation kinetics evaluated by near infrared spectroscopy technique (NIRS). Eleven adult men completed 20-day unloading and were divided into two groups; the control (CON) group and training (TR) group. The TR group engaged in exercise training sessions that consisted of one-legged submaximal cycle exercise using the unloaded leg at 60 similar to 80% of (V) over dotO(2peak) with intermittent rest periods, 25 min/day every other day. All Subjects performed isometric knee extension exercise at 50% of their maximum voluntary contraction force before and after unloading. NIRS Delta[deoxy-Hb/Mb] signal was recorded from m. vastus lateralis and was fitted to an exponential equation in order to determine the kinetics parameters. The time constant (tau) of the % Delta[deoxy-Hb/Mb] was unchanged in the TR group, while it significantly increased in the CON group after unloading(pre, 5.0 +/- 1.0; post, 7.4 +/- 1.0s). It is concluded that 20-day unloading increased the T, suggesting deterioration of capacity for oxidative phosphorylation and oxygen utilization in a skeletal muscle. Additionally, the preservation Of T in the TR group suggested that intensive interval training could have an impact on the maintenance of muscle oxidative metabolism during unloading.

    DOI: 10.1055/s-0029-1202824

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  69. Cycle ergometer exercise to counteract muscle atrophy during unilateral lower limb suspension.

    Akima H, Hotta N, Sato K, Ishida K, Koike T, Katayama K

    Aviation, space, and environmental medicine   Vol. 80 ( 7 ) page: 652-6   2009.7

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    DOI: 10.3357/asem.2399.2009

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  70. Effect of two durations of short-term intermittent hypoxia on ventilatory chemosensitivity in humans.

    Katayama K, Ishida K, Iwasaki K, Miyamura M

    European journal of applied physiology   Vol. 105 ( 5 ) page: 815-21   2009.3

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    DOI: 10.1007/s00421-008-0960-y

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  71. *Effect of two durations of short-term intermittent hypoxia on ventilatory chemosensitivity in humans. Reviewed

    Katayama, K., K. Ishida, K. Iwasaki, and M. Miyamura.

    Eur. J. Appl. Physiol.   Vol. 105   page: 483-491   2009

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    The purpose of this study was to clarify the influence of duration of intermittent hypoxia per day on ventilatory chemosensitivity. Subjects were assigned to 3 different groups according to the duration of exposure to intermittent hypoxia (12.3% O2): A first group (H-1, n=6) was exposed to hypoxia for 1 hour per day, the second group (H-2, n=6) was exposed for 3 hours per day, and the third (C, n= 7) was used as control. Hypoxic and hypercapnic ventilatory responses (HVR and HCVR) were determined before and after 1 week of intermittent hypoxia. HVR was increased significantly (P<0.05) after intermittent hypoxia in both the H-1 and H-2 groups. However, there was no significant difference in magnitude of increased HVR between H-1 and H-2 groups. HCVR did not show any changes in all groups after intermittent hypoxia. These results suggest that 1 hour of daily exposure is as equally effective as 3 hours of daily exposure to severe hypoxia for a short period for enhancing ventilatory chemosensitivity to hypoxia.

  72. Effect of intensive interval cycling training during unilateral lower limb unloading on aerobic capacity

    Keisho Katayama, Kohei Sato, Norio Hotta, Koji Ishida, Kohei Watanabe, Kazumi Masuda, Motohiko Miyachi, Teruhiko Koike, Hiroshi Akima

    Japanese Journal of Physical Fitness and Sports Medicine   Vol. 57 ( 1 ) page: 84   2008

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    DOI: 10.7600/jspfsm.57.84

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  73. Chronic intermittent hypoxia increases the CO2 reserve in sleeping dogs

    Katayama Keisho, Smith Curtis A., Henderson Kathleen S., Dempsey Jerome A.

    JOURNAL OF APPLIED PHYSIOLOGY   Vol. 103 ( 6 ) page: 1942-1949   2007.12

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    DOI: 10.1152/japplphysiol.00735.2007

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  74. Effect of arterial oxygenation on quadriceps fatigability during isolated muscle exercise.

    Katayama K, Amann M, Pegelow DF, Jacques AJ, Dempsey JA

    American journal of physiology. Regulatory, integrative and comparative physiology   Vol. 292 ( 3 ) page: R1279-86   2007.3

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    DOI: 10.1152/ajpregu.00554.2006

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  75. Intermittent hypoxia does not increase exercise ventilation at simulated moderate altitude. Reviewed

    Katayama, K., K. Sato, N. Hotta, K. Ishida, K. Iwasaki, and M. Miyamura.

    Int. J. Sports Med.   Vol. 28   page: 480-487   2007

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    Recent human studies have shown that resting hypoxic ventilatory response (HVR), which is an index of ventilatory chemosensitivity to hypoxia, increased after short-term intermittent hypoxia at rest. In addition, intermittent hypoxia leads to increases in ventilation and arterial oxygen saturation (SaO (2)) during exercise at simulated high altitude, with the increase in ventilation correlated to the change in HVR. However, no study has been made to clarify the relationship between ventilatory chemosensitivity and the exercise ventilation at moderate altitude following intermittent hypoxia during a resting state. The purpose of the present study, therefore, was to elucidate whether intermittent hypoxia at rest induces the increase in ventilation during exercise at moderate altitude that is accompanied by an increase in hypoxic chemosensitivity. Eighteen trained male runners were assigned to three groups, i.e., the first hypoxic group (H-1 group, n = 6), the second hypoxic group (H-2 group, n = 6), and a control group (C group, n = 6). The hypoxic tent system was utilized for intermittent hypoxia, and the oxygen levels in the tent were maintained at 15.5 +/- 0.1 % (simulated 2500 m altitude) for the H-1 group and 12.3 +/- 0.2 % (simulated 4300 m altitude) for the H-2 group. The H-1 and H-2 groups spent 1 hour per day in the hypoxic tent for 1 week. Maximal and submaximal exercise tests while breathing 15.5 +/- 0.01 % O (2) (simulated altitude of 2500 m) were performed before and after intermittent hypoxia. Resting HVR was also determined in each subject using a progressive isocapnic hypoxic method. In the H-2 group, HVR increased significantly (p < 0.05) following intermittent hypoxia, while no change in HVR was found in the H-1 or C group. Neither ventilation nor SaO (2) during maximal and submaximal exercise at a simulated altitude of 2500 m were changed in either group after 1 hour per day for 1 week of intermittent hypoxia. These results suggest that the change i

  76. Chronic intermittent hypoxia increases the CO2 reserve in sleeping dogs. Reviewed

    Katayama, K., C. A. Smith, K. S. Henderson, and J. A. Dempsey.

    J. Appl. Physiol.   Vol. 103   page: 1973-1978   2007

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  77. *The effect of arterial oxygenation on quadriceps fatigability during isolated muscle exercise. Reviewed

    Katayama, K., M. Amann, D. F. Pagelow, A. J. Jacques, and J. A. Dempsey.

    Am. J. Physiol. Regul. Integr. Physiol.   Vol. 292   page: R1279-R1286   2007

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    The effect of various levels of oxygenation on quadriceps muscle fatigability during isolated muscle exercise was assessed in six male subjects. Twitch force (Qtw) was assessed using supra-maximal magnetic femoral nerve stimulation. In Experiment I, maximal voluntary contraction (MVC) and Qtw of resting quadriceps muscle were measured in nomoxia [arterial O2 saturation (SpO2) = 98.4; NORM], acute-hypoxia (SpO2 = 74.6%; HYPO), and acute-hyperoxia (SpO2 = 100%; HYPER). No significant differences were found for MVC and Qtw among the three FIO2s. In Experiment II, the subjects performed three sets of nine, intermittent, isometric, unilateral, submaximal quadriceps contractions (62% MVC) while breathing each FIO2. Qtw was assessed before and after exercise, and myoelectrical activity of the vastus lateralis was obtained during exercise. The percent reduction of twitch force (potentiated Qtw) in HYPO (-27.0%) was significantly (P<0.05) greater than those in NORM (-21.4%) and HYPER (-19.9%). The increase in integrated electromyogram over the course of the nine contractions in HYPO (15.4%) was higher (P<0.05) than in NORM (7.2%) or HYPER (6.7%). These results demonstrate that quadriceps muscle fatigability during isolated muscle exercise is exacerbated in acute hypoxia, and these effects were independent of the relative exercise intensity.

  78. Comments on Point:Counterpoint "Positive effects of intermittent hypoxia (live high:train low) on exercise performance are/are not mediated primarily by augmented red cell volume".

    Katayama K

    Journal of applied physiology (Bethesda, Md. : 1985)   Vol. 99 ( 6 ) page: 2460   2005.12

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  79. Intensive cycle training with artificial gravity maintains muscle size during bed rest.

    Akima H, Katayama K, Sato K, Ishida K, Masuda K, Takada H, Watanabe Y, Iwase S

    Aviation, space, and environmental medicine   Vol. 76 ( 10 ) page: 923-9   2005.10

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  80. Changes In Ventilatory Responses To Hypercapnia And Hypoxia After Intermittent Hypoxia In Trained Athletes

    Katayama Keisho, Sato Kohei, Matsuo Hiroshi, Hotta Norio, Sun Zhihu, Ishida Koji, Iwasaki Ken-ichi, Miyamura Miharu

    MEDICINE AND SCIENCE IN SPORTS AND EXERCISE   Vol. 37   page: S294-S294   2005.5

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  81. Changes in ventilatory responses to hypercapnia and hypoxia after intermittent hypoxia in humans

    Katayama K, Sato K, Matsuo H, Hotta N, Sun ZH, Ishida K, Iwasaki K, Miyamura M

    RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY   Vol. 146 ( 1 ) page: 55-65   2005.3

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    DOI: 10.1016/j.resp.2004.11.007

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  82. Vestibulo-cardiorespiratory responses at the onset of chair rotation in endurance runners.

    Sato K, Katayama K, Katayama N, Hotta N, Ishida K, Miyamura M

    The Japanese journal of physiology   Vol. 55 ( 1 ) page: 11-8   2005.2

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    DOI: 10.2170/jjphysiol.R2069

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  83. *Changes in ventilatory responses to hypercapnia and hypoxia after intermittent hypoxia in humans. Reviewed

    Katayama, K.,K. Sato, H. Matsuo, N. Hotta, Z. Sun, K. Ishida, K. Iwasaki, and M. Miyamura.

    Respir. Physiol. Neurobiol.   Vol. 146   page: 55-65   2005

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    The purpose of this study was to clarify the changes in hypercapnic and hypoxic ventilatory responses (HCVR and HVR) after intermittent hypoxia and following the cessation of hypoxic exposure. Twenty-nine males were assigned to one of four groups, i.e., a hypoxic (EX1-H, n=7) or a control (EX1-C, n=7) group in Experiment 1, and a hypoxic (EX2-H, n=8) or a control (EX2-C, n=7) group in Experiment 2. In each experiment, the hypoxic tent system was utilized for intermittent hypoxia, and the oxygen levels in the tent were maintained at 12.3+/-0.2%. In Experiment 1, the EX1-H group spent 3 h/day in the hypoxic tent for 1 week. HCVR and HVR were determined before and after 1 week of intermittent hypoxia, and again 1 and 2 week after the cessation of hypoxic exposure. In Experiment 2, the subjects in the EX2-H group performed 3 h/day for 2 weeks in intermittent hypoxia. HCVR and HVR tests were carried out before and after intermittent hypoxia, and were repeated again after 2 weeks of the cessation of hypoxic exposure. The slope of the HCVR in the EX1-H group did not show a significant increase after 1 week of intermittent hypoxia, while HCVR in the EX2-H group increased significantly after 2 weeks of intermittent hypoxia. The HCVR intercept was unchanged following 1 or 2 weeks of intermittent hypoxia. There was a significant increase in the slope of the HVR after 1 and 2 weeks of intermittent hypoxia. The increased HCVR and HVR returned to pre-hypoxic levels after 2 weeks of the cessation of hypoxia. These results suggest that 3 h/day for 2 weeks of intermittent hypoxia leads to an increase in central hypercapnic ventilatory chemosensitivity, which is not accompanied by a re-setting of the central chemoreceptors, and that the increased hypercapnic and hypoxic chemosensitivities are restored within 2 weeks after the cessation of hypoxia.

  84. Effect of a repeated series of intermittent hypoxic exposures on ventilatory response in humans. Reviewed

    Katayama, K.,H. Fujita, K. Sato, K. Ishida, K. Iwasaki, and M. Miyamura.

    High Alt. Med. Biol.   Vol. 6   page: 50-59   2005

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  85. Acceleration with exercise during head-down bed rest preserves upright exercise responses.

    Katayama K, Sato K, Akima H, Ishida K, Takada H, Watanabe Y, Iwase M, Miyamura M, Iwase S

    Aviation, space, and environmental medicine   Vol. 75 ( 12 ) page: 1029-35   2004.12

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  86. Ventilatory and heart rate responses at the onset of chair rotation in man.

    Miyamura M, Ishida K, Katayama K, Shima N, Matsuo H, Sato K

    The Japanese journal of physiology   Vol. 54 ( 5 ) page: 499-503   2004.10

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    DOI: 10.2170/jjphysiol.54.499

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  87. Effect of centrifuge-induced artificial gravity and ergometric exercise on cardiovascular deconditioning, myatrophy, and osteoporosis induced by a -6 degrees head-down bedrest.

    Iwase S, Takada H, Watanabe Y, Ishida K, Akima H, Katayama K, Iwase M, Hirayanagi K, Shiozawa T, Hamaoka T, Masuo Y, Custaud MA

    Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology   Vol. 11 ( 2 ) page: P243-4   2004.7

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  88. Effect of intermittent hypoxia on oxygen uptake during submaximal exercise in endurance athletes.

    Katayama K, Sato K, Matsuo H, Ishida K, Iwasaki K, Miyamura M

    European journal of applied physiology   Vol. 92 ( 1-2 ) page: 75-83   2004.6

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    DOI: 10.1007/s00421-004-1054-0

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  89. Ventilatory and circulatory responses at the onset of voluntary exercise and passive movement in sprinters.

    Sato K, Matsuo H, Katayama K, Ishida K, Honda Y, Katsumata K, Miyamura M

    European journal of applied physiology   Vol. 92 ( 1-2 ) page: 196-203   2004.6

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    DOI: 10.1007/s00421-004-1075-8

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  90. Ventilatory and cardiovascular responses to hypercapnia after 20 days of head-down bed rest.

    Katayama K, Sato K, Akima H, Ishida K, Yanagiya T, Kanehisa H, Fukuoka H, Fukunaga T, Miyamura M

    Aviation, space, and environmental medicine   Vol. 75 ( 4 ) page: 312-6   2004.4

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  91. Effects of 20 days head-down bed rest on ventilatory and cardiovascular responses to hypercapnia. Reviewed

    Katayama, K., K. Sato, H. Akima, K. Ishida, T. Yanagiya, H. Kanehisa, H. Fukuoka, T. Fukunaga, and M. Miyamura.

    Aviat. Space Environ. Med.   Vol. 75   page: 312-316   2004

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  92. Effect of intermittent hypoxia on oxygen uptake during submaximal exercise in endurance athletes. Reviewed

    Katayama, K., K. Sato, H. Matsuo, K. Ishida, K. Iwasaki, and M. Miyamura.

    Eur. J. Appl. Physiol.   Vol. 92   page: 75-83   2004

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  93. Effects of intermittent hypoxic training and detraining on ventilatory chemosensitive adaptations in endurance athletes. Reviewed

    Katayama, K., K. Sato, H. Matsuo, K. Ishida, S. Mori, and M. Miyamura.

    Adv. Exp. Med. Biol.   Vol. 551   page: 299-304   2004

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  94. Effects of 20 days head-down bed rest on ventilatory and cardiovascular responses to hypercapnia. Reviewed

    Katayama, K., K. Sato, H. Akima, K. Ishida, T. Yanagiya, H. Kanehisa, H. Fukuoka, T. Fukunaga, and M. Miyamura.

    Aviat. Space Environ. Med.   Vol. 75   page: 313-316   2004

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  95. Effect of intermittent hypoxia on oxygen uptake during submaximal exercise in endurance athletes. Reviewed

    Katayama, K., K. Sato, H. Matsuo, K. Ishida, K. Iwasaki, and M. Miyamura.

    Eur. J. Appl. Physiol.   Vol. 92   page: 75-83   2004

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  96. Effects of intermittent hypoxic training and detraining on ventilatory chemosensitive adaptations in endurance athletes. Reviewed

    Katayama, K., K. Sato, H. Matsuo, K. Ishida, S. Mori, and M. Miyamura.

    Adv. Exp. Med. Biol.   Vol. 551   page: 299-304   2004

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  97. Acceleration with exercise during head-down bed rest preserves upright exercise responses. Reviewed

    Katayama, K., K. Sato, H. Akima, K. Ishida, H. Takada, Y. Watanabe, M. Iwase, M. Miyamura, and S. Iwase.

    Aviat. Space Environ. Med.   Vol. 75   page: 1029-1035   2004

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  98. Effects of intermittent hypoxic training and detraining on ventilatory chemosensitive adaptations in endurance athletes.

    Katayama K, Sato K, Matsuo H, Ishida K, Mori S, Miyamura M

    Advances in experimental medicine and biology   Vol. 551   page: 299-304   2004

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    DOI: 10.1007/0-387-27023-x_45

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  99. Effect of menstrual cycle and gender on ventilatory and heart rate responses at the onset of exercise.

    Matsuo H, Katayama K, Ishida K, Muramatsu T, Miyamura M

    European journal of applied physiology   Vol. 90 ( 1-2 ) page: 100-8   2003.9

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    DOI: 10.1007/s00421-003-0873-8

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  100. Cardiorespiratory responses to hypoxia and hypercapnia at rest in vocalists.

    Miyamura M, Ishida K, Katayama K, Sato Y, Morotome Y, Shima N, Matsuo H, Sato K

    The Japanese journal of physiology   Vol. 53 ( 1 ) page: 17-24   2003.2

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  101. Intermittent hypoxia improves endurance performance and submaximal exercise efficiency. Reviewed

    Katayama, K., H. Matsuo, K. Ishida, S. Mori, and M. Miyamura.

    High Alt. Med. Biol.   Vol. 4   page: 291-304   2003

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  102. Effect of cycling experience and pedal cadence on the near-infrared spectroscopy parameters.

    Takaishi T, Ishida K, Katayama K, Yamazaki K, Yamamoto T, Moritani T

    Medicine and science in sports and exercise   Vol. 34 ( 12 ) page: 2062-71   2002.12

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    DOI: 10.1097/00005768-200212000-00030

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  103. Enhanced chemosensitivity after intermittent hypoxic exposure does not affect exercise ventilation at sea level.

    Katayama K, Sato Y, Shima N, Qiu JC, Ishida K, Mori S, Miyamura M

    European journal of applied physiology   Vol. 87 ( 2 ) page: 187-91   2002.6

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    DOI: 10.1007/s00421-002-0594-4

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  104. Is man able to breathe once a minute for an hour?: the effect of yoga respiration on blood gases.

    Miyamura M, Nishimura K, Ishida K, Katayama K, Shimaoka M, Hiruta S

    The Japanese journal of physiology   Vol. 52 ( 3 ) page: 313-6   2002.6

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    DOI: 10.2170/jjphysiol.52.313

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  105. Changes in blood volume and oxygenation level in a working muscle during a crank cycle.

    Takaishi T, Sugiura T, Katayama K, Sato Y, Shima N, Yamamoto T, Moritani T

    Medicine and science in sports and exercise   Vol. 34 ( 3 ) page: 520-8; discussion 529   2002.3

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  106. Cross education of muscular strength during unilateral resistance training and detraining.

    Shima N, Ishida K, Katayama K, Morotome Y, Sato Y, Miyamura M

    European journal of applied physiology   Vol. 86 ( 4 ) page: 287-94   2002.2

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    DOI: 10.1007/s00421-001-0559-z

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  107. Enhanced chemosensitivity after intermittent hypoxic exposure does not affect exercise ventilation at sea level. Reviewed

    Katayama, K., Y. Sato, N. Shima, J. Qiu, K. Ishida, S. Mori, and M. Miyamura.

    Eur. J. Appl. Physiol   Vol. 87   page: 187-191   2002

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    The purpose of the present study was to test the hypothesis that the ventilatory response to exercise at sea level may increase after intermittent hypoxic exposure for 1 week, accompanied by an increase in hypoxic or hypercapnic ventilatory chemosensitivity. One group of eight subjects (hypoxic group) were decompressed in a chamber to 432 torr (where 1 torr=1.0 mmHg, simulating an altitude of 4,500 m) over a period of 30 min and maintained at that pressure for 1 h daily for 7 days. Oxygen uptake and pulmonary ventilation (V(E)) were determined at 40%, 70%, and 100% of maximal oxygen uptake at sea level before (Pre) and after (Post) 1 week of daily exposures to hypoxia. The hypoxic ventilatory response (HVR) was determined using the isocapnic progressive hypoxic method as an index of ventilatory chemosensitivity to hypoxia, and the hypercapnic ventilatory response (HCVRSB) was measured by means of the single-breath carbon dioxide method as an index of peripheral ventilatory chemosensitivity to hypercapnia. The same parameters were measured in another group of six subjects (control group). In the hypoxic group, resting HVR increased significantly ( P<0.05) after intermittent hypoxia and HCVRSB increased at Post, but the change was not statistically significant ( P=0.07). In contrast, no changes in HVR and HCVRSB were found in the control group. There were no changes in either V(E) or the ventilatory equivalent for oxygen during maximal and submaximal exercise at sea level throughout the experimental period in either group. These results suggest that the changes in resting hypoxic and peripheral hypercapnic chemosensitivities following short-term intermittent hypoxia have little effect on exercise ventilation at sea level.

  108. Effect of intermittent hypoxia on cardiovascular adaptations and response to progressive hypoxia in humans. Reviewed

    Katayama, K., N. Shima, Y. Sato, J. Qiu, K. Ishida, S. Mori, and M. Miyamura.

    High Alt. Med. Biol.   Vol. 2   page: 501-508   2001

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    The aim of the present study was to elucidate (1) the cardiovascular adaptations and response to hypoxic stimuli during short-term intermittent hypoxia and (2) whether the change in cardiovascular response to hypoxia is correlated to the change in hypoxic ventilatory chemosensitivity. Fourteen subjects were decompressed in a chamber to 432 torr, simulating an altitude of 4500 m, over a period of 30 min and were maintained at that pressure for 1 h daily for 7 days. Ventilatory (DeltaV(I)/DeltaSa(O2); Sa(O2) is arterial oxygen saturation), systolic and diastolic blood pressure (DeltaSBP/DeltaSa(O2) and DeltaDBP/DeltaSa(O2)), and heart rate (DeltaHR/DeltaSa(O2)) responses to progressive isocapnic hypoxia were measured before and after intermittent hypoxia. Resting ventilation, SBP, DBP, and HR did not change after intermittent hypoxia. DeltaSBP/DeltaSa(O2) and DeltaDBP/DeltaSa(O2) increased significantly after intermittent hypoxia accompanied by an enhanced DeltaV(I)/DeltaSa(C2), but there was no change in DeltaHR/DeltaSa(C2). There were significant correlations between the change in DeltaV(I)/DeltaSa(O2) and both the changes in DeltaSBP/DeltaSa(O2) and DeltaDBP/DeltaSa(O2) following intermittent hypoxic exposure. These results suggest that short-term intermittent hypoxia leads to the enhanced arterial BP response to hypoxic stimuli in humans, and that the enhanced peripheral chemosensitivity to hypoxia after intermittent hypoxia may play an important role in the increased arterial BP response.

  109. Intermittent hypoxia increases ventilation and SaO2 during hypoxic exercise and hypoxic chemosensitivity. Reviewed

    Katayama, K., Y. Sato, Y. Morotome, N. Shima, K. Ishida, S. Mori, and M. Miyamura.

    J. Appl. Physiol.   Vol. 90   page: 1431-1440   2001

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    The purpose of this study was 1) to test the hypothesis that ventilation and arterial oxygen saturation (Sa(O2)) during acute hypoxia may increase during intermittent hypoxia and remain elevated for a week without hypoxic exposure and 2) to clarify whether the changes in ventilation and Sa(O2) during hypoxic exercise are correlated with the change in hypoxic chemosensitivity. Six subjects were exposed to a simulated altitude of 4,500 m altitude for 7 days (1 h/day). Oxygen uptake (VO2), expired minute ventilation (VE), and Sa(O2) were measured during maximal and submaximal exercise at 432 Torr before (Pre), after intermittent hypoxia (Post), and again after a week at sea level (De). Hypoxic ventilatory response (HVR) was also determined. At both Post and De, significant increases from Pre were found in HVR at rest and in ventilatory equivalent for O2 (VE/VO2) and Sa(O2) during submaximal exercise. There were significant correlations among the changes in HVR at rest and in VE/VO2 and Sa(O2) during hypoxic exercise during intermittent hypoxia. We conclude that 1 wk of daily exposure to 1 h of hypoxia significantly improved oxygenation in exercise during subsequent acute hypoxic exposures up to 1 wk after the conditioning, presumably caused by the enhanced hypoxic ventilatory chemosensitivity.

  110. Ventilatory and circulatory responses at the onset of voluntary exercise and passive movement in children Reviewed

    Y Sato, K Katayama, K Ishida, M Miyamura

    EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY   Vol. 83 ( 6 ) page: 516 - 523   2000.12

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    The purpose of this study was to investigate whether or not the ventilatory and circulatory responses at the onset of voluntary exercise and passive movement, especially at the initial stage (phase I), in children are the same as in adults. Ten pre-teenage male children and ten adult men participated in this study. Voluntary exercise and passive movement were performed in a sitting position for about 20 s. Both the exercise and the movement consisted of flexion-extensions of the lower leg from a vertical to horizontal position, either voluntarily or passively, with a frequency of about 60.min(-1). Inspiratory minute ventilation ((V) over dot(I)), tidal volume (V-T), respiratory frequency, partial pressure of end-tidal CO2 and O-2, heart rate (f(c)) and mean blood pressure ((BP) over bar) before, during and after exercise or movement were measured using breath-by-breath and beat-to-beat techniques. Cardiorespiratory responses at the onset of voluntary exercise and passive movement were compared with the relative change (Delta), which was estimated from the value at rest (100%). In the present study, it was found that: (1) the V-I during voluntary exercise were significantly lower in the children, mainly due to lower DeltaV(T); (2) the Deltaf(c) during voluntary exercise was almost the same in both groups, while Deltaf(c) was significantly lower in the children during the last part of passive movement; (3) in the voluntary exercise and passive movement, the (BP) over bar in the children was increased a little or remained close to the value at rest, while it was significantly decreased in the adults. As a result, there were significant differences in Delta(BP) over bar between the two groups during voluntary exercise. These results suggest that the cardiorespiratory responses at the onset of voluntary exercise and passive movement may be modified during the growth process.

    Web of Science

  111. Cardiovascular response to hypoxia after endurance training at altitude and sea level and after detraining Reviewed

    K Katayama, Y Sato, Y Morotome, N Shima, K Ishida, S Mori, M Miyamura

    JOURNAL OF APPLIED PHYSIOLOGY   Vol. 88 ( 4 ) page: 1221 - 1227   2000.4

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    The pur pose of this study was to elucidate 1) the effects of endurance exercise training during hypoxia or normoxia and of detraining on ventilatory and cardiovascular responses to progressive isocapnic hypoxia and 2) whether the change in the cardiovascular response to hypoxia is correlated to changes in the hypoxic ventilatory response (HVR) after training and detraining. Seven men (altitude group) performed endurance training using a cycle ergometer in a hypobaric chamber of simulated 4,500 m, whereas the other seven men (sea-level group) trained at sea level (K. Katayama, Y. Sate, Y. Morotome, N. Shima, K. Ishida, S. Mori, and M. Miyamura. J. Appl. Physiol. 86: 1805-1811, 1999). The HVR, systolic and diastolic blood pressure responses (Delta SBP/Delta Sa(O2), Delta DBP/Delta Sa(O2)), and heart rate response (Delta HR/Delta Sa(O2) Sa(O2) is arterial oxygen saturation) to progressive isocapnic hypoxia were measured before and after training and during detraining. Delta SBP/Delta Sa(O2) increased significantly in the altitude group and decreased significantly in the sea-level group after training. The changed Delta SBP/Delta Sa(O2) in both groups was restored during 2 wk of detraining, as were the changes in HVR, whereas there were no changes in the Delta DBP/Delta Sa(O2) and Delta HR/Delta Sa(O2) throughout the experimental period. The changes in Delta SBP/Delta Sa(O2)? after training and detraining were significantly correlated with those in HVR. These results suggest that Delta SBP/Delta Sa(O2), to progressive isocapnic hypoxia is variable after endurance training during hypoxia and normoxia and after detraining, as is HVR, but Delta DBP/Delta Sa(O2) and Delta HR/Sa(O2) are not. It also suggests that there is an interaction between the changes in Delta SBP/Delta Sa(O2) and HVR after endurance training or detraining.

    Web of Science

  112. Cardiovascular response to isocapnic hypoxia after endurance training at altitude, sea level, and detraining. Reviewed

    Katayama, K., Y. Sato, Y. Morotome, N. Shima, K. Ishida, S. Mori, and M. Miyamura

    J. Appl. Physiol.   Vol. 88   page: 1221-1227   2000

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    Language:English   Publishing type:Research paper (scientific journal)  

    The purpose of this study was to elucidate 1) the effects of endurance exercise training during hypoxia or normoxia and of detraining on ventilatory and cardiovascular responses to progressive isocapnic hypoxia and 2) whether the change in the cardiovascular response to hypoxia is correlated to changes in the hypoxic ventilatory response (HVR) after training and detraining. Seven men (altitude group) performed endurance training using a cycle ergometer in a hypobaric chamber of simulated 4,500 m, whereas the other seven men (sea-level group) trained at sea level (K. Katayama, Y. Sato, Y. Morotome, N. Shima, K. Ishida, S. Mori, and M. Miyamura. J. Appl. Physiol. 86: 1805-1811, 1999). The HVR, systolic and diastolic blood pressure responses (DeltaSBP/DeltaSa(O(2)), DeltaDBP/DeltaSa(O(2))), and heart rate response (DeltaHR/DeltaSa(O(2)); Sa(O(2)) is arterial oxygen saturation) to progressive isocapnic hypoxia were measured before and after training and during detraining. DeltaSBP/DeltaSa(O(2)) increased significantly in the altitude group and decreased significantly in the sea-level group after training. The changed DeltaSBP/DeltaSa(O(2)) in both groups was restored during 2 wk of detraining, as were the changes in HVR, whereas there were no changes in the DeltaDBP/DeltaSa(O(2)) and DeltaHR/DeltaSa(O(2)) throughout the experimental period. The changes in DeltaSBP/DeltaSa(O(2)) after training and detraining were significantly correlated with those in HVR. These results suggest that DeltaSBP/DeltaSa(O(2)) to progressive isocapnic hypoxia is variable after endurance training during hypoxia and normoxia and after detraining, as is HVR, but DeltaDBP/DeltaSa(O(2)) and DeltaHR/DeltaSa(O(2)) are not. It also suggests that there is an interaction between the changes in DeltaSBP/DeltaSa(O(2)) and HVR after endurance training or detraining.

  113. Ventilatory chemosensitive adaptations to intermittent hypoxic exposure with endurance training and detraining Reviewed

    K Katayama, Y Sato, Y Morotome, N Shima, K Ishida, S Mori, M Miyamura

    JOURNAL OF APPLIED PHYSIOLOGY   Vol. 86 ( 6 ) page: 1805 - 1811   1999.6

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    The present study was performed to clarify the effects of intermittent exposure to an altitude of 4,500 m with endurance training and detraining on ventilatory chemosensitivity. Seven subjects (sea-level group) trained at sea level at 70% maximal oxygen uptake ((V) over doto(2max)) for 30 min/day, 5 days/wk for 2 wk, whereas the other seven subjects (altitude group) trained at the same relative intensity (70% altitude (V) over doto(2max)) in a hypobaric chamber. (V) over doto(2max) hypoxic ventilatory response (HVR), and hypercapnic ventilatory response, as an index of central hypercapnic chemosensitivity (HCVR) and as an index of peripheral chemosensitivity (HCVRSB), were measured. In both groups (V) over doto(2max) increased significantly after training, and a significant loss of (V) over doto(2max) occurred during 2 wk of detraining. HVR tended to increase in the altitude group but not significantly, whereas it decreased significantly in the sea-level group after training. HCVR and HCVRSB did not change in each group. After detraining, HVR returned to the pretraining level in both groups. These results suggest that ventilatory chemosensitivity to hypoxia is more variable by endurance training and detraining than that to hypercapnia.

    Web of Science

  114. Ventilatory chemosensitive adaptations to intermittent hypoxic exposure with endurance training and detraining. Reviewed

    Katayama, K., Y. Sato, Y. Morotome, N. Shima, K. Ishida, S. Mori, and M. Miyamura.

    J. Appl. Physiol   Vol. 86   page: 1805-1811   1999

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    The present study was performed to clarify the effects of intermittent exposure to an altitude of 4,500 m with endurance training and detraining on ventilatory chemosensitivity. Seven subjects (sea-level group) trained at sea level at 70% maximal oxygen uptake (VO2 max) for 30 min/day, 5 days/wk for 2 wk, whereas the other seven subjects (altitude group) trained at the same relative intensity (70% altitude VO2 max) in a hypobaric chamber. VO2 max, hypoxic ventilatory response (HVR), and hypercapnic ventilatory response, as an index of central hypercapnic chemosensitivity (HCVR) and as an index of peripheral chemosensitivity (HCVRSB), were measured. In both groups VO2 max increased significantly after training, and a significant loss of VO2 max occurred during 2 wk of detraining. HVR tended to increase in the altitude group but not significantly, whereas it decreased significantly in the sea-level group after training. HCVR and HCVRSB did not change in each group. After detraining, HVR returned to the pretraining level in both groups. These results suggest that ventilatory chemosensitivity to hypoxia is more variable by endurance training and detraining than that to hypercapnia.

  115. Effects of maximal interval training on arterial oxygen desaturation and ventilation during heavy exercise

    Motohiko Miyachi, Keisho Katayama

    Japanese Journal of Physiology   Vol. 49 ( 5 ) page: 401 - 407   1999

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:The Physiological Society of Japan  

    The purpose of the present study was to clarify longitudinally the effects of exercise training on arterial O2 saturation (Sa(O)2) and ventilation during heavy exercise. A group of six subjects (training group) volunteered to train four times a week for 12 weeks. Each training session consisted of five 3-min periods of exercise on a cycle ergometer at a power output of 100% maximal O2 uptake (V̇O(2 max)), interspersed with 2 min recovery period cycling at 50% V̇O(2 max). During the training, V̇O(2 max), Sa(O)2, the ventilatory equivalent for oxygen (V̇E/V̇O2), and the end- tidal partial pressure of O2 (PET(O)2) during heavy exercise were measured periodically. The same parameters were measured simultaneously in another group of five subjects (control group) who led normal lives. Maximal interval training increases V̇O(2 max), with little change in V̇E(max) and pulmonary functions at rest. The training decreased PET(O)2, V̇E/V̇O2, and Sa(O)2 during heavy exercise. Sa(O)2 is significantly related to V̇E/V̇O2 (r2 = 0.49). These results suggest that less hyperventilatory response to exercise occurs with progress in physical training because the adaptability of ventilatory capacity is less than that of aerobic work capacity, which half induces arterial O2 desaturation during heavy exercise. PET(O)2 as well as V̇E/V̇O2 and V̇O(2 max) did not change anymore after the 6th week, nevertheless Sa(O)2 kept decreasing up to the last 2 weeks. In addition, when the Sa(O)2-V̇E/V̇O2 plot was compared between the two groups, the regression line of the training group was steeper than that of the control groups
    i.e., compared at a lower level of V̇E/V̇O2 (~30 ml · ml-1), the Sa(O)2 of the trained subjects exercising at a higher V̇O2 level was lower than that of the control subjects. Predominance of less hyperventilation and another factor, increased A-aDO2, in the genesis of arterial hypoxemia and O2 desaturation may be dependent upon V̇O2 levels in heavy exercise and the state of training.

    DOI: 10.2170/jjphysiol.49.401

    Scopus

    PubMed

  116. The effects of intermittent exposure to hypoxia during endurance exercise training on the ventilatory responses to hypoxia and hypercapnia in humans Reviewed

    Keisho Katayama, Yasutake Sato, Koji Ishida, Shigeo Mori, Miharu Miyamura

    European Journal of Applied Physiology and Occupational Physiology   Vol. 78 ( 3 ) page: 189 - 194   1998.8

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    The present study was performed to investigate the effects of a combination of intermittent exposure to hypoxia during exercise training for short periods on ventilatory responses to hypoxia and hypercapnia (HVR and HCVR respectively) in humans. In a hypobaric chamber at a simulated altitude of 4500 m (barometric pressure 432 mmHg), seven subjects (training group) performed exercise training for 6 consecutive days (30 min·day-1), while six subjects (control group) were inactive during the same period. The HVR, HCVR and maximal oxygen uptake (V̇O(2max)) for each subject were measured at sea level before (pre) and after exposure to intermittent hypoxia. The post exposure test was carried out twice, i.e. on the 1st day and 1 week post exposure. It was found that HVR, as an index of peripheral chemosensitivity to hypoxia, was increased significantly (P &lt
    0.05) in the control group after intermittent exposure to hypoxia. In contrast, there was no significant increase in HVR in the training group after exposure. The HCVR in both groups was not changed by intermittent exposure to hypoxia, while V̇O(2max) increased significantly in the training group. These results would suggest that endurance training during intermittent exposure to hypoxia depresses the increment of chemosensitivity to hypoxia, and that intermittent exposure to hypoxia in the presence or absence of exercise training does not induce an increase in the chemosensitivity to hypercapnia in humans.

    DOI: 10.1007/s004210050406

    Scopus

    PubMed

  117. The effects of intermittent exposure to hypoxia during endurance exercise training on the ventilatory responses to hypoxia and hypercapnia in humans. Reviewed

    Katayama, K., Y. Sato, K. Ishida, S. Mori, and M. Miyamura.

    Eur. J. Appl. Physiol.   Vol. 78   page: 189-194   1998

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    Language:English   Publishing type:Research paper (scientific journal)  

    The present study was performed to investigate the effects of a combination of intermittent exposure to hypoxia during exercise training for short periods on ventilatory responses to hypoxia and hypercapnia (HVR and HCVR respectively) in humans. In a hypobaric chamber at a simulated altitude of 4,500 m (barometric pressure 432 mmHg), seven subjects (training group) performed exercise training for 6 consecutive days (30 min x day(-1)), while six subjects (control group) were inactive during the same period. The HVR, HCVR and maximal oxygen uptake (VO2max) for each subject were measured at sea level before (pre) and after exposure to intermittent hypoxia. The post exposure test was carried out twice, i.e. on the 1st day and 1 week post exposure. It was found that HVR, as an index of peripheral chemosensitivity to hypoxia, was increased significantly (P < 0.05) in the control group after intermittent exposure to hypoxia. In contrast, there was no significant increase in HVR in the training group after exposure. The HCVR in both groups was not changed by intermittent exposure to hypoxia, while VO2max increased significantly in the training group. These results would suggest that endurance training during intermittent exposure to hypoxia depresses the increment of chemosensitivity to hypoxia, and that intermittent exposure to hypoxia in the presence or absence of exercise training does not induce an increase in the chemosensitivity to hypercapnia in humans.

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Books 12

  1. *Effect of intermittent hypoxia on hypoxic ventilatory response. In: Intermittent hypoxia. Eds. L. Xi and T. V. Serebrovskaya

    Katayama, K.( Role: Sole author)

    Nova Science Publishers  2009 

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    Intermittent exposure to hypoxia occurs in many circumstances in human life. The purpose of this chapter is to summarize the ventilatory responses to hypoxia at rest and during exercise after intermittent hypoxia in non-pathophysiological situations in humans. It seems clear that intermittent exposure to severe hypoxia (above 4300m altitude or less than 13% FIO2), associated with rapid ascents to and descents from high altitudes, leads to an increase in hypoxic ventilatory response (HVR), even if the duration per day and the period of the exposure are relatively short (below 5 hours per day for 1 week). In addition, the ventilatory response to exercise at simulated high altitude increased after intermittent hypoxia, while ventilatory response to exercise at sea level was not augmented by intermittent hypoxia. When the magnitude of hypoxia is moderate (15-16% FIO2), longer durations and/or periods of the exposure (more than 8 hours per day for several weeks) are needed to obtain an increased HVR. The enhanced HVR persists but falls off with time over 2 weeks after the cessation of hypoxic exposure, i.e., during deacclimatization.

  2. *Arterial oxygenation and muscle fatigue. In: Advance in neuromuscular physiology of motor skills and muscle fatigue. Ed. M. Shinohara

    K. Katayama and M. Amann( Role: Joint author)

    Research Signpost  2009 

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    Language:English

    Exercise-induced muscle fatigue can be defined as a reversible
    reduction in the force or power generating capacity of a muscle or muscle
    group. If exercise is submaximal, measurable fatigue can occur
    without a forfeit in task performance as additional motor units or muscles
    are recruited to compensate for those that are fatiguing. It is well
    documented that decreases or increases in oxygen transport to contracting
    skeletal muscle influence work performance during whole body
    and isolated muscle exercise in humans. The physiological
    mechanisms underpinning this phenomenon are complex and interactive,
    and it has been proposed that the effects of altered muscle O2 delivery
    [arterial O2 content (CaO2) x blood flow] on exercise performance are
    mediated via its impact on the rate of development of "central" and
    "peripheral" fatigue. In this chapter, we discuss evidence documenting the
    effects of altered arterial O2 transport on the development of peripheral and central fatigue during exercise.

  3. 運動時の換気応答,身体トレーニング(宮村實晴 編)

    片山敬章( Role: Sole author)

    真興交易(株)医書出版部  2009 

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    Language:Japanese

  4. Pulmonary responses to exercise and limitations to human performance. In: Physiological bases of human performance during work and exercise. Eds. N. A. S. Taylor and H. Groeller

    Stickland, M., M. Amann, K. Katayama, and J. Dempsey.( Role: Joint author)

    Elsevier  2008 

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    Language:English

  5. 換気の化学調節・最新スポーツ科学事典([社]日本体育学会監修)

    ( Role: Joint author)

    平凡社  2006 

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    Language:Japanese

  6. 換気量・最新スポーツ科学事典([社]日本体育学会監修)

    ( Role: Joint author)

    平凡社  2006 

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    Language:Japanese

  7. 換気の化学調節.運動と呼吸(宮村實晴編集)

    片山敬章( Role: Joint author)

    真興交易(株)医書出版部  2004 

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    Language:Japanese

  8. 呼吸の科学感受性.新運動生理学(下巻)(宮村實晴編集)

    片山敬章,宮村實晴( Role: Joint author)

    真興交易(株)医書出版部  2001 

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    Language:Japanese

  9. スポーツと高所・低酸素トレーニング,スポーツ生理学(冨樫健二編集)

    片山敬章( Role: Joint author)

    (株)化学同人  2013 

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    Language:Japanese

  10. スポーツと呼吸,スポーツ生理学(冨樫健二編集)

    片山敬章( Role: Joint author)

    (株)化学同人  2013 

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    Language:Japanese

  11. 呼吸の化学調節.身体運動と呼吸・循環機能(宮村実晴編集)

    片山敬章( Role: Sole author)

    真興交易(株)医書出版部  2012 

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    Language:Japanese

  12. 換気の化学調節,運動生理学のニューエビデンス(宮村実晴編集)

    片山敬章( Role: Sole author)

    真興交易(株)医書出版部  2011 

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MISC 64

  1. 低酸素環境における運動中の動脈血酸素飽和度の低下は認知機能の向上を減弱させる

    小見山高明, 片山敬章, 須藤みず紀, 石田浩司, 檜垣靖樹, 安藤創一

    日本運動生理学会大会プログラム・抄録集   Vol. 25th   2017

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  2. Cognitive Function And Affective States Following Exercise Under Severe Hypoxia.

    Mizuki Sudo, Takaaki Komiya, Toshiya Nagamatsu, Yasuki Higaki, Koji Ishida, Keisho Katayama, Soichi Ando

    MEDICINE AND SCIENCE IN SPORTS AND EXERCISE   Vol. 48 ( 5 ) page: 420 - 420   2016.5

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    Language:English   Publishing type:Research paper, summary (international conference)   Publisher:LIPPINCOTT WILLIAMS & WILKINS  

    DOI: 10.1249/01.mss.0000486263.72930.6d

    Web of Science

  3. Hypoxia Attenuates Cardiopulmonary Reflex Control Of The Sympathetic Nerve Activity During Dynamic Leg Exercise

    Keisho Katayama, Koji Ishida, Mitsuru Saito, Teruhiko Koike, Shigehiko Ogoh

    MEDICINE AND SCIENCE IN SPORTS AND EXERCISE   Vol. 48 ( 5 ) page: 312 - 312   2016.5

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    Language:English   Publishing type:Research paper, summary (international conference)   Publisher:LIPPINCOTT WILLIAMS & WILKINS  

    DOI: 10.1249/01.mss.0000485940.50122.a0

    Web of Science

  4. Effect Of Immobilization On Intramuscular Fat Of The Thigh Muscle Groups

    Akito Yoshiko, Koun Yamauchi, Chisato Kato, Takayuki Kato, Keisho Katayama, Koji Ishida, Teruhiko Koike, Yoshiharu Oshida, Hiroshi Akima, Katsumi Asano

    MEDICINE AND SCIENCE IN SPORTS AND EXERCISE   Vol. 47 ( 5 ) page: 726 - 726   2015.5

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    Language:English   Publishing type:Research paper, summary (international conference)   Publisher:LIPPINCOTT WILLIAMS & WILKINS  

    DOI: 10.1249/01.mss.0000478708.46897.d1

    Web of Science

  5. Expiratory Resistive Loading Increases in Sympathetic Vasomotor Outflow and BP During Dynamic Leg Exercise

    Keisho Katayama, Yuka Itoh, Mitsuru Saito, Teruhiko Koike, Koji Ishida

    MEDICINE AND SCIENCE IN SPORTS AND EXERCISE   Vol. 47 ( 5 ) page: 684 - 684   2015.5

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    Language:English   Publishing type:Research paper, summary (international conference)   Publisher:LIPPINCOTT WILLIAMS & WILKINS  

    DOI: 10.1249/01.mss.0000466134.69741.59

    Web of Science

  6. 正常体重の男性でカロリー制限と運動が体組成と代謝に及ぼす効果

    KOIKE TERUHIKO, KATAYAMA KEISHO, NATSUME YUKIE, IWAMOTO ERIKA, ISHIDA KOJI, OSHIDA YOSHIHARU

    Campus Health   Vol. 52 ( 1 ) page: 285 - 285   2015.3

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    Language:Japanese   Publishing type:Research paper, summary (international conference)   Publisher:(公社)全国大学保健管理協会  

    J-GLOBAL

  7. 動的運動における筋ポンプ作用の増加は筋交感神経活動を抑制する

    KATAYAMA KEISHO, ISHIDA KOJI, SAITO MITSURU, HIRASAWA AI, KOIKE TERUHIKO, OGAWA SHIGEHIKO

    体力科学   Vol. 63 ( 6 ) page: 587 - 587   2014.12

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    Language:Japanese   Publishing type:Research paper, summary (international conference)   Publisher:(一社)日本体力医学会  

    J-GLOBAL

  8. 短期間の低酸素トレーニングによる運動時換気亢進の学習効果

    ISHIDA KOJI, KATAYAMA KEISHO, KOIKE TERUHIKO, YAMAUCHI KOUN, ITO YUKA, HOTTA NORIO, IWAMOTO ERIKA

    体力科学   Vol. 63 ( 6 ) page: 583 - 583   2014.12

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  9. 運動強度の違いが低酸素環境における非活動肢の逆流性血流量に与える影響

    IWAMOTO ERIKA, KATAYAMA KEISHO, ISHIDA KOJI

    体力科学   Vol. 63 ( 6 ) page: 578 - 578   2014.12

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  10. 正常体重男性でのカロリー制限時における運動負荷の糖代謝への影響

    KOIKE TERUHIKO, KATAYAMA KEISHO, IWAMOTO ERIKA, ISHIDA KOJI, OSHIDA YOSHIHARU

    体力科学   Vol. 63 ( 5 ) page: 486 - 486   2014.10

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  11. 正常体重の男性でカロリー制限と運動が体組成と代謝に及ぼす効果

    KOIKE TERUHIKO, KATAYAMA KEISHO, NATSUME YUKIE, IWAMOTO ERIKA, ISHIDA KOJI, OSHIDA YOSHIHARU

    全国大学保健管理研究集会プログラム・抄録集   Vol. 52nd   page: 70 - 70   2014.8

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  12. Effects Of Acute Aerobic Exercise In Hypoxia On Brachial Flow-mediated Dilation

    Shin Yamashita, Keisho Katayama, Erika Iwamoto, Koji Ishida

    MEDICINE AND SCIENCE IN SPORTS AND EXERCISE   Vol. 46 ( 5 ) page: 746 - 746   2014.5

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  13. Sympathetic Outflow during Leg Cycling is Suppressed by Muscle Pump-Induced Increase in Central Blood Volume

    Keisho Katayama, Shin Yamashita, Koji Ishida, Mitsuru Saito, Teruhiko Koike, Shigehiko Ogoh

    MEDICINE AND SCIENCE IN SPORTS AND EXERCISE   Vol. 46 ( 5 ) page: 328 - 328   2014.5

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  14. Exercise Intensity Affects Brachial Retrograde Blood Flow During Leg Cycling In Hypoxia

    Erika Iwamoto, Keisho Katayama, Shin Yamashita, Koji Ishida

    MEDICINE AND SCIENCE IN SPORTS AND EXERCISE   Vol. 46 ( 5 ) page: 746 - 746   2014.5

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  15. 低酸素環境における吸気抵抗の増加が循環応答へ及ぼす影響

    片山敬章, 山下晋, 石田浩司, 岩本えりか, 小池晃彦, 齊藤満

    体力科学   Vol. 63 ( 1 ) page: 113 - 113   2014.2

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    DOI: 10.7600/jspfsm.63.113

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  16. 高強度運動時の心拍同期性交感神経活動反応の検討

    齊藤満, 山本薫, 片山敬章, 石田浩司

    愛知学院大学論叢 心身科学部紀要   Vol. 10   page: 1-7   2014

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  17. 低酸素環境における一過性の有酸素性運動が非活動肢の血管機能に及ぼす影響

    山下晋, 片山敬章, 岩本えりか, 石田浩司

    体力科学   Vol. 62 ( 6 ) page: 527 - 527   2013.12

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    DOI: 10.7600/jspfsm.62.527

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  18. 胸郭制限トレーニングによる運動時換気亢進の学習効果

    石田浩司, 片山敬章, 山下晋, 岩本えりか, 堀田典生

    体力科学   Vol. 62 ( 6 ) page: 622 - 622   2013.12

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    DOI: 10.7600/jspfsm.62.622

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  19. 運動強度の違いが非活動肢の血流パターンへ及ぼす影響

    岩本えりか, 片山敬章, 山下晋, 押田芳治, 石田浩司

    体力科学   Vol. 62 ( 6 ) page: 619 - 619   2013.12

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  20. 低酸素環境における有酸素性運動が非活動肢の血管内皮機能に及ぼす影響

    山下晋, 片山敬章, 岩本えりか, 石田浩司

    体力科学   Vol. 62 ( 3 ) page: 257 - 257   2013.6

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  21. Effects of Inspiratory Resistive Breathing in Hypoxia on Sympathetic Outflow and Blood Pressure During Exercise

    Keisho Katayama, Shin Yamashita, Koji Ishida, Erika Iwamoto, Teruhiko Koike, Mitsuru Saito

    MEDICINE AND SCIENCE IN SPORTS AND EXERCISE   Vol. 45 ( 5 ) page: 634 - 634   2013.5

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  22. Oscillatory Blood Flow Pattern in the Brachial Artery During Hypoxic Constant Load Leg Cycling

    Erika Iwamoto, Keisho Katayama, Shin Yamashita, Masaki Katayose, Yoshiharu Oshida, Koji Ishida

    MEDICINE AND SCIENCE IN SPORTS AND EXERCISE   Vol. 45 ( 5 ) page: 515 - 515   2013.5

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  23. AGREEプロジェクトの進展 : エルゴメーター運動を伴う人工重力の有効性に関する多国間プロジェクトの進捗状況

    岩瀬 敏, 西村 直記, 菅屋 潤壹, PALOSKI Willam H., YOUNG Laurence R., VAN LOON Jack J. W. A., WUYTS Floris, CLEMENT Gilles, RITTWEGER Jorn, GERZER Rupert, LACKNER Japes, 秋間 広, 片山 敬章, 傳 〓

    日本生理学雜誌   Vol. 75 ( 1 ) page: 30 - 31   2013.1

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  24. 低酸素トレーニングと生活習慣病 ー循環系への影響ー

    片山敬章, 荻田太

    体育の科学   Vol. 63   page: 151 - 155   2013

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  25. 定常負荷運動時の運動種目による呼気中アセトン濃度変動の比較 Reviewed

    永峰康一郎, 原亜珠沙, 野津真知子, 石田浩司, 片山敬章, 近藤孝晴

    安定同位体と生体ガス   Vol. 5   page: 44-51   2013

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  26. 低酸素環境が定常負荷運動中の血流パターンに与える影響

    岩本えりか, 片山敬章, 片寄正樹, 押田芳治, 石田浩司

    体力科学   Vol. 61 ( 6 ) page: 754 - 754   2012.12

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    DOI: 10.7600/jspfsm.61.754

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  27. 呼吸筋の疲労による運動時の循環応答

    片山敬章, 岩本えりか, 石田浩司, 小池晃彦, 山下晋, 齊藤満

    体力科学   Vol. 61 ( 6 ) page: 597 - 597   2012.12

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    DOI: 10.7600/jspfsm.61.597

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  28. 胸郭制限が定常負荷運動時の呼吸循環応答に及ぼす影響

    石田浩司, 片山敬章, 岩本えりか, 堀田典生, 杉浦弘通

    体力科学   Vol. 61 ( 6 ) page: 598 - 598   2012.12

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  29. Decrease In Blood Flow To Nonworking Limb During Incremental Exercise In Hypoxia

    Erika Iwamoto, Keisho Katayama, Yoshiharu Oshida, Koji Ishida

    JOURNAL OF GENERAL INTERNAL MEDICINE   Vol. 27   page: 646 - 646   2012.7

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  30. The Effects of Chest Wall Restriction on Cardio-respiratory Responses, Muscle Oxygenation and Performance during Exercise

    石田 浩司, 片山 敬章, 岩本 えりか

    デサントスポーツ科学   Vol. 33   page: 33 - 42   2012.6

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    胸部圧迫による胸郭制限が,持久的運動のパフォーマンスおよび生理学的機能にどのような影響を及ぼすか明らかにするため,9名の被検者に,ストラップで胸部を締める胸郭制限(CR)条件と非制限(NR)条件で,漸増負荷による最大運動テストを行った.さらに,CR条件での最高酸素摂取量の40,60,80%の運動強度で15分間の最大下の定常負荷運動テストも実施した.その結果,NR条件に比べCR条件では,1)最高酸素摂取量と運動継続時間は低下し,80%強度の定常負荷運動で3名の被検者が運動継続できなくなった,2)毎分換気量は80%より下の運動強度では高いがその最大値は低く,その影響で80%強度以上で動脈血酸素飽和度(SpO2)は低下する,3)一回換気量は低く,呼吸数は高い,4)筋の脱酸素化率は80%強度では差がないが,それ以外は低い傾向を示す,5)乳酸濃度は最高値は低いが,最大下および乳酸閾値や乳酸蓄積開始点(OBLA)は差がない,6)呼吸の疲労度(困難感)が高い,ことが明らかとなった.胸郭制限により持久的運動のパフォーマンスが低下し,それには呼吸系の機能低下が直接的に影響することが示唆された.(著者抄録)

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  31. 運動時の神経性循環調節に対する持久トレーニング効果

    齊藤満, 片山敬章, 石田浩司, 岩本えりか, 金尾洋治, 家光素行

    日本運動生理学会大会プログラム・抄録集   Vol. 20th   page: 58   2012

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  32. 低酸素環境が非運動肢における血流パターンに及ぼす影響

    岩本えりか, 片山敬章, 石田浩司, 押田芳治

    体力科学   Vol. 60 ( 6 ) page: 651 - 651   2011.12

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  33. 低酸素環境での運動による血流依存性血管拡張能への影響

    片山敬章, 家光素行, 河野寛, 岩本えりか, 齊藤満, 石田浩司

    体力科学   Vol. 60 ( 3 ) page: 371 - 371   2011.6

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  34. Muscle Sympathetic Activity During Submaximal Cycling Exercise In Hypoxia

    Keisho Katayama, Koji Ishida, Erika Iwamoto, Motoyuki Iemitsu, Teruhiko Koike, Mitsuru Saito

    MEDICINE AND SCIENCE IN SPORTS AND EXERCISE   Vol. 43 ( 5 ) page: 152 - 152   2011.5

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  35. 二人乗り自転車エルゴメーター運動時の心拍数と酸素摂取量変化

    小野寺昇, BAIK Wooram, 藤原有子, 片山敬章, 荻田太, 吉岡哲, 河野寛, 西村一樹, 山口英峰, 関和俊, 高橋康輝, 枝松千尋, 飯田智行, 荒金圭太, 斎藤辰哉, 野瀬由佳, 高木祐介, 松本希, 高原皓全, 古本佳代

    体力科学   Vol. 60 ( 1 ) page: 172 - 172   2011.2

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  36. The effect of intense interval cycle-training on umloading-induced dysfunction and atrophy in the human calf muscle. Reviewed

    Norio hotta, Koji Ishida, Kohei Sato, Teruhiko Koike, Keisho Katayama, Hiroshi Akima

    J Physiol Anthropol   Vol. 30 ( 1 ) page: 29-35   2011

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  37. 低酸素環境における動的運動時の筋交感神経活動とノルエピネフリン反応

    片山敬章, 岩本えりか, 石田浩司, 家光素行, 齊藤満

    日本運動生理学会大会プログラム・抄録集   Vol. 19th   page: 62   2011

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  38. サルコペニアの今:サルコペニアの対策、予防と治療 Invited

    小池晃彦, 秋間広, 柳本有二, 片山敬章, 石田浩司, 坂崎貴彦, 夏目有紀枝, 押田芳治

    運動・物理療法   Vol. 22 ( 3 ) page: 307-314   2011

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  39. 1-B-05 Effect of acute hypoxia on muscle sympathetic nerve activity during dynamic leg exercise(The Proceedings of the 19th Annual Meetings of Japan Society of Exercise and Sports Physiology August 25・26, (Tokushima)) :

    KATAYAMA Keisho, IWAMOTO Erika, ISHIDA Koji, IEMITSU Motoyuki, SAITO Mitsuru

    Advances in exercise and sports physiology   Vol. 17 ( 2 ) page: 57 - 57   2011

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    Other Link: https://projects.repo.nii.ac.jp/?action=repository_uri&item_id=194266

  40. 低酸素環境における動的運動時の呼吸循環応答

    片山敬章, 石田浩司, 岩本えりか, 家光素行, 小池晃彦, 斉藤満

    体力科学   Vol. 59 ( 6 ) page: 697 - 697   2010.12

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  41. Muscle Deoxygenation and Myoelectric Activity During Sustained and Intermittent Isometric Exercise in Hypoxia

    Keisho Katayama, Yasuhide Yoshitake, Kohei Watanabe, Hiroshi Akima, Koji Ishida

    MEDICINE AND SCIENCE IN SPORTS AND EXERCISE   Vol. 42 ( 5 ) page: 466 - 466   2010.5

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  42. Effects of deconditioning on the initial ventilatory and circulatory responses at the onset of exercise in man

    Ishida, K, Katayama K, Akima H, Iwase S, Sato K, Hotta N, Miyamura M

    Adv. Exp. Med. Biol.   Vol. 669   page: 319-322   2010

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  43. 名古屋大学における「健康・スポーツ科学実習」授業に関する学生の意識調査-実習を選択しない学生の観点から-

    石田浩司, 西田保, 蛭田秀一, 片山敬章, 山本裕二, 石黒洋, 小池晃彦, 小林洋平

    総合保健体育科学   Vol. 33 ( 1 ) page: 49-63   2010

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  44. The adaptive responses in several mediators linked with hypertrophy and atrophy of skeletal muscle after lower limb unloading in humans. Reviewed

    K. Sakuma, W Kohei, N Norio, T Koike, K Ishida, K Katayama, H Akima

    Acta Physiologica   Vol. 197   page: 151-159   2009

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  45. 短期間の間欠的低酸素暴露が持久的鍛練者の呼吸循環応答に及ぼす影響

    片山敬章, 石田浩司, 斉藤満

    デサントスポーツ科学   Vol. 30   page: 15-23   2009

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  46. 模擬微小重力暴露後により生ずる体液移動への対抗措置の効果

    櫻井博紀, 岩瀬敏, 菅屋潤壹, 増尾義久, 西村直記, 山田陽介, 太田めぐみ, 富田真司, 福永哲夫, 石田浩司, 秋間広, 片山敬章, 清水祐樹, 佐藤麻紀, KANIKOWSKA Dominika, 鈴木里美, 渡邉順子, 平柳要, 塩沢友規

    日本宇宙航空環境医学会大会プログラム・予稿集   Vol. 54th   page: 43   2008.10

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  47. Effects Of Low Frequency Intensive Interval Training On Muscle Atrophy And Function During Unloading

    Hiroshi Akima, Kohei Watanabe, Keisho Katayama, Koji Ishida, Teruhiko Koike

    MEDICINE AND SCIENCE IN SPORTS AND EXERCISE   Vol. 40 ( 5 ) page: S351 - S351   2008.5

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  48. Recruitment Patterns of The Adductor Muscles During Incremental Fatiguing Pedaling

    Kohei Watanabe, Keisho Katayama, Koji Ishida, Hiroshi Akima

    MEDICINE AND SCIENCE IN SPORTS AND EXERCISE   Vol. 40 ( 5 ) page: S351 - S351   2008.5

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  49. 20日間の-6°ヘッドダウンベッドレスト後の起立耐性に対する人工重力および運動負荷の有効性

    Space Utilization Research   Vol. 24   page: 271   2008

  50. Head-down bed restにより生ずる体液移動と筋萎縮への対抗措置の効果.

    Space Utilization Research   Vol. 24   page: 278   2008

  51. Effect of countermeasure on body fluid shift and myatrophy induced by head-down bed rest in human healthy volunteers

    Sakurai Hiroki, Ishida Koji, Akima Hiroshi, Katayama Keisyou, Shimizu Yuuki, Sato Maki, Dominika Kanikowska, Suzuki Satomi, Watanabe Yoriko, Hirayanagi Kaname, Shiozawa Tomoki, Iwase Satoshi, Sugenoya Junichi, Masuo Yoshihisa, Nishimura Naoki, Yamada Yosuke, Ohta Megumi, Tomita Shinji, Fukunaga Tetsuo

    Proceedings of Annual Meeting of the Physiological Society of Japan   Vol. 2008 ( 0 ) page: 108 - 108   2008

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    Exposure of humans to microgravity condition resulted in body fluid shift and myatrophy. The aim of this study was to test the effectiveness of artificial gravity and ergometric exercise as countermeasure to these changes. 12 healthy young men were exposed to stimulated microgravity for 20 days by head-down bed rest. 6 subjects randomly selected were subjected to 1.4G of artificial gravity with 60W of ergometric workload everyday for 30 minutes (CM group). The rest of the subjects served as the control (control group). In head-up tilt test and Anti-G test, body fluid shift measured by segmental bioimpedance method was smaller in the trunk in CM group than in control group. Also, myatrophy measured by MRI in the thigh was smaller in CM group than in control group. Artificial gravity with exercise appeared to be effective in preventing changes in body fluid shift and myatrophy due to microgravity exposure. &lt;b&gt;[J Physiol Sci. 2008;58 Suppl:S108]&lt;/b&gt;

  52. Ventilatory and heart rate responses at the onset of passive movement in eudurance- and sprint runners.

    Miyamura, M, Sato, K, Hashimoto, I, Yuza, N, Matsuo, H, Ishida, K, Katayama, K

      Vol. 11   page: 3-16   2007

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  53. Effect of Intermittent Hypoxia on Exercise Ventilation at a Simulated Moderate Altitude

    Keisho Katayama, Kohei Sato, Norio Hotta, Koji Ishida, Ken-ichi Iwasaki, Miharu Miyamura

    MEDICINE AND SCIENCE IN SPORTS AND EXERCISE   Vol. 38 ( 5 ) page: S524 - S525   2006.5

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  54. The Influence of Unilateral Lower Limb Suspension on Cardiorespiratory Response during Exercise

    Kohei Sato, Keisho Katayama, Norio Hotta, Koji Ishida, Motohiko Miyachi, Kazumi Masuda, Hiroshi Akima

    MEDICINE AND SCIENCE IN SPORTS AND EXERCISE   Vol. 38 ( 5 ) page: S391 - S391   2006.5

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  55. 片脚サスペンジョンが運動開始直後の呼吸・循環応答に及ぼす影響 Reviewed

    堀田典生, 佐藤耕平, 片山敬章, 秋間広, 石田浩司

    東海保健体育科学   Vol. 28   page: 21-27   2006

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  56. 下肢サスペンジョンとベッドレストにおける筋萎縮の比較

    秋間広, 堀田典生, 佐藤耕平, 片山敬章, 石田浩司, 岩瀬敏

    宇宙航空環境医学   Vol. 42 ( 4 )   2005.12

  57. Effect Of High Intensity Cycle Training With Artificial Hypergravity During Bed Rest On Skeletal Muscle

    Hiroshi Akima, Keisho Katayama, Kohei Sato, Koji Ishida, Kazumi Masuda, Hiroki Takada, Yoriko Watanabe, Satoshi Iwase

    MEDICINE AND SCIENCE IN SPORTS AND EXERCISE   Vol. 37   page: S33 - S33   2005.5

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    Language:English   Publishing type:Research paper, summary (international conference)   Publisher:LIPPINCOTT WILLIAMS & WILKINS  

    Web of Science

  58. Cardiorespiratory responses at the onset of chair rotation in the open-and closed-eye conditions.

      Vol. 10   page: 45-56   2005

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  59. 酸素充填水摂取は運動時の呼吸・循環応答に影響を及ぼすか?

    堀田典生, 片山敬章, 佐藤耕平, 孫志虎, 山本親, 中塚正博, 石田浩司

    総合保健体育科学   Vol. 28   page: 23-28   2005

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    酸素水が持久力を高めるか否かを明らかにするため、長距離選手を被検者に2回に分けてどちらか告げずに酸素水または普通の水を飲ませ(二重盲検法)、その後トレッドミルで疲労困憊まで走らせ、両条件を比較した。その結果、酸素摂取量や心拍数、走行時間など、全ての項目で両者に差は認められず、酸素水は持久力を向上させる効果はないことが明らかとなった。

  60. Effect of intermittent hypoxia on ventilatory responses to hypoxia and hypercapnia in endurance athletes

    K Katayama, K Sato, H Matsuo, K Ishida, K Iwasaki, M Miyamura

    MEDICINE AND SCIENCE IN SPORTS AND EXERCISE   Vol. 36 ( 5 ) page: S265 - S265   2004.5

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    Web of Science

  61. :Effect of microgravity exposure on R-R variability and influence of a countermeasure

    Takada Hiroki, Iwase Satoshi, Watanabe Yoriko, Iwase Mitsunori, Katayama Keisyo, Akima Hiroshi, Ishida Kouji, Miyao Masaru, Shiozawa Tomonori, Hirayanagi Kaname

    JES Ergonomics   Vol. 40   page: 320 - 321   2004

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  62. Intermittent hypoxia increases ventilation and Sa(O2) during hypoxic exercise and hypoxic chemosensitivity Reviewed

    K Katayama, Y Sato, Y Morotome, N Shima, K Ishida, S Mori, M Miyamura

    JOURNAL OF APPLIED PHYSIOLOGY   Vol. 90 ( 4 ) page: 1431 - 1440   2001.4

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    The purpose of this study was 1) to test the hypothesis that ventilation and arterial oxygen saturation (SaO(2)) during acute hypoxia may increase during intermittent hypoxia and remain elevated for a week without hypoxic exposure and 2) to clarify whether the changes in ventilation and Sa,, during hypoxic exercise are correlated with the change in hypoxic chemosensitivity. Six subjects were exposed to a simulated altitude of 4,500 m altitude for 7 days (1 h/day). Oxygen uptake (Vo(2)), expired minute ventilation (V-E), and SaO(2) were measured during maximal and submaximal exercise at 432 Torr before (Pre), after intermittent hypoxia (Post), and again after a week at sea level (De). Hypoxic ventilatory response (HVR) was also determined. At both Post and De, significant increases from Pre were found in HVR at rest and in ventilatory equivalent for O-2 (V-E/VO2) and Sa(O2) during submaximal exercise. There were significant correlations among the changes in HVR at rest and in (V) over dot(E)/(V) over dotO(2) and Sa(O2) during hypoxic exercise during intermittent hypoxia. We conclude that 1 wk of daily exposure to 1 h of hypoxia significantly improved oxygenation in exercise during subsequent acute hypoxic exposures up to 1 wk after the conditioning, presumably caused by the enhanced hypoxic ventilatory chemosensitivity.

    Web of Science

  63. Ventilatory and circulatory responses at the onset of rapid changes in posture Reviewed

    Miyamura M, Ishida K, Katayama K, Sato Y, Shima N

    Adv Exp Med Biol   Vol. 499   page: 357 - 362   2001

  64. *Initial ventilatory and circulatory responses to dynamic exercise are slowed in the elderly Reviewed

    Ishida, K, Sato, Y, Katayama, K, Miyamura, M

    Journal of Applied Physiology   Vol. 89 ( 5 ) page: 1771-1777   2000

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▼display all

Presentations 2

  1. 呼吸筋活動の増加に対する循環応答:年齢および性別の影響

    126. 清水香,塩澤華奈,齊藤満,石田浩司,水野沙洸,秋間広,片山敬章

    第75回 日本体力医学会大会  2020.9 

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    Event date: 2020.9

    Language:Japanese  

  2. 動的運動時の呼吸筋活動増加による循環応答:性差の影響

    塩澤華奈,清水香,齊藤満,石田浩司,水野沙洸,片山敬章

    第75回 日本体力医学会大会  2020.9 

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    Event date: 2020.9

Research Project for Joint Research, Competitive Funding, etc. 4

  1. 低酸素環境における有酸素性運動が血管拡張能に及ぼす影響

    2011.4 - 2012.3

    健康医科学研究助成 

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    Grant type:Competitive

  2. 低酸素環境下での運動による糖代謝,脂質代謝に関する研究

    2008.4 - 2009.3

    YMFSスポーツチャレンジ助成 

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    Grant type:Competitive

  3. 運動時の呼吸循環応答に及ぼす低酸素暴露後の影響について

    2008.4 - 2009.3

    石本記念デサントスポーツ科学振興財団 

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    Grant type:Competitive

  4. 低酸素に対する呼吸の化学感受性の変化ー低酸素濃度の違いによる比較ー

    2005.4 - 2006.3

    市原国際奨学財団 

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    Grant type:Competitive

KAKENHI (Grants-in-Aid for Scientific Research) 35

  1. 間欠的な低酸素暴露による運動効率の改善に関する研究

    2003.4 - 2005.3

    科学研究費補助金  若手研究(B)

    片山 敬章

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    Authorship:Principal investigator 

  2. 低酸素暴露に対する身体適応の反復効果

    2005.4 - 2007.3

    科学研究費補助金  若手研究(B)

    片山 敬章

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  3. 低酸素環境における運動時の呼吸循環調節メカニズムの解明

    2008.4 - 2010.3

    科学研究費補助金  若手研究(B)

    片山 敬章

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  4. 呼吸系が運動時の循環調節に及ぼす影響

    2012.4 - 2015.3

    科学研究費補助金  基盤研究(B)

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    Authorship:Principal investigator 

  5. 低酸素環境を利用した呼吸筋トレーニングの開発と持久的パフォーマンスへの効果

    2014.4 - 2017.3

    科学研究費補助金 

    片山敬章

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  6. 運動時の循環調節およびパフォーマンスに対する呼吸筋活動の影響

    2015.4 - 2018.3

    科学研究費補助金  基盤研究(B)

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  7. 運動時の循環調節に対する呼吸筋活動の影響と心肺圧受容器反射の役割

    2017.4 - 2019.3

    科学研究費補助金  国際共同研究加速基金(国際共同研究強化)

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  8. 運動時の呼吸をシミュレートした新しい呼吸筋トレーニングの開発

    2019.6 - 2022.3

    科学研究費補助金 

  9. Developing a new respiratory muscle training: mimicking exercise-induced hyperpnoea

    Grant number:19K22803  2019.6 - 2022.3

    Grant-in-Aid for Challenging Research (Exploratory)

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    Authorship:Principal investigator 

    Grant amount:\6110000 ( Direct Cost: \4700000 、 Indirect Cost:\1410000 )

  10. Arterial blood pressure regulation during exercise by muscle pump and cardiopulmonary baroreflex

    Grant number:19H03998  2019.4 - 2022.3

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    Grant amount:\17420000 ( Direct Cost: \13400000 、 Indirect Cost:\4020000 )

  11. Effect of muscle activation and contraction type on respiratory muscle warm-up and training

    Grant number:18K10880  2018.4 - 2021.3

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  12. タンデム自転車エルゴメータを用いた受動動作による末梢及び中枢血流応答

    Grant number:18K10950  2018.4 - 2021.3

    小野寺 昇

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    [研究の目的] タンデム自転車エルゴメータを用いれば、例えば前乗り被験者が能動ペダリングを担当すれば、後ろ乗り被験者は、受動動作のペダリングが可能となる。この方法を用いることにより受動的動作での筋血流量増大、筋温上昇、心拍数や酸素摂取量の増大を確認できる。受動的動作での末梢の活性化が脳血流の促進に寄与するのであれば、受動的な動作においても中枢の活性化が生じるという学術的な「問い」に答えることができると考えた。本研究の目的は、受動的なペダリング運動(passive movement)時の筋血流量と脳血流量の関連性の解明にある。
    [研究実施計画] 本研究は、筋血流量と脳血流量を定量し、心拍数・酸素摂取量との関連性を明らかにする計画を立てている。
    [研究の成果の具体的な内容] 回転数に依存する受動ペダル運動時の心拍数と前頭前野酸化ヘモグロビン濃度変化の関連性を明らかにした.被験者は成人男性7名であった.被験者は、受動的および能動的なペダリング運動(運動負荷;1.5kp、15分間)を行った.ペダル回転数は40rpmから80rpmとし,3分ごとに10rpmずつ増加させた.心拍数は心電計を用いて測定し、前頭前野の酸化ヘモグロビン濃度は、全頭測定型functional NIRS装置を用いて測定した.研究手順は、川崎医療福祉大学の倫理委員会によって承認された。心拍数は受動ペダル運動時および能動ペダル運動時にペダル回転数の増加に伴い有意に増加した.受動ペダル運動時の酸化ヘモグロビン濃度は,運動前に比べ80rpmにおいて有位に増加した.これらの増加は,能動ペダル運動に同調する受動動作の影響であると考えられた。受動ペダル運動者における前頭前野の血流量は増加した。
    [研究の成果の意義・重要性]  本研究成果は、受動的動作での末梢の活性化が脳血流の促進に寄与する重要なエビデンスとなり、受動的動作が中枢を活性化させる可能性を示唆する意義を持つと考えられる。
    本研究は、筋血流量と脳血流量を定量し、心拍数・酸素摂取量との関連性を明らかにする計画を立てている。研究開始から2年間経過し、受動ペダリング運動時の心拍数及び酸素摂取量がペダル回転数の増加に依存し、その増加は、有意であることを確認している。
    2019年度には、受動ペダリング運動時の前頭前野の酸化ヘモグロビン濃度を全頭測定型functional NIRS装置を用いて測定し、脳血流量の定量への取り組みとした。その研究成果を「受動ペダル運動時の心拍数と前頭前野酸化ヘモグロビン濃度変化の関連性」として国際学会であるECSS2020(European College of Sport Science 2020, Spain)にエントリーした。ポスター演題としてアクセプトされているが、新型コロナウィルスによる影響で会期が延期になり、しかも開催地がスペインであることから参加の可否を勘案している。
    2020年3月に受動ペダリング運動時の筋血流量と脳血流量の関連性に関する実験を計画していたが、新型コロナウィルスによる影響で実験実施場所である川崎医療福祉大学への分担研究者の移動が困難になったため、実験を延期している。
    本研究課題の目標は、①筋血流量を定量し、酸素摂取量との関連性を明らかにすること、②脳血流量を定量し、酸素摂取量との関連性を明らかにすること、③筋血流量と脳血流量との関連性を明らかにすること、としている。
    ①と②については、すでにデータ取得済であるが新型コロナウィルスによる影響により、国内だけでなく、海外の学会の開催の延期になっているため、 PDCAサイクルにおけるCheck項目である学会発表などのよる研究成果の公表と評価を飛ばして学術誌への論文投稿を成果公表(DO)として推進する方策を立案している。
    遅れている③の実験については、新型コロナウィルスによる影響が落ち着いた段階での実験の再開を計画することとする。
    ②の研究成果から当初予想していなかった新しい知見を見出した。受動ペダル運動者における前頭前野の血流量は増加したが、その一方で能動ペダル運動者の酸化ヘモグロビン濃度変化は,ペダル回転数の増加に伴い抑制された.なぜ抑制されたのか。ペダリング運動が定型運動であるためなのか、それとも、運動野における血流増加による前頭前野の血流抑制なのか。この知見に関する情報収集も進めたい。
    本研究の目標は、受動的動作での末梢の活性化が脳血流の促進に寄与する重要なエビデンスとなることを検証するにある。受動的動作が中枢を活性化させる可能性を示唆する意義を持つ研究成果に結びつけたい。

  13. Interrelationships among cognitive, motor and cardio-respiratory functions during cognitive and exercise dual task performance

    Grant number:17K01758  2017.4 - 2020.3

    Ishida Koji

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    We investigated motor and cognitive dual-task performance with different task types or difficulties, and how aging affects them. We also explored the cardio-respiratory responses at the onset of dual-tasking.
    The results were as follows: 1) The accuracy of motor tasks was decreased with cadences different from the preferred one, especially in elderly participants who pedaled more rapidly during slower condition. Dual-tasking deteriorated cognitive performance in all cadences and age groups. 2) The accuracy and constancy of motor tasks deteriorated with dual-tasking involving working memory regardless of age, while attention function was more affected by dual-tasks, and surprisingly improved in the elderly at difficult visual-search task. 3) Most cardio-respiratory responses were greater during dual-tasking compared with exercise only and were slower in the elderly. These increased responses by dual task were explained by the simple arithmetic sum of cognitive and motor effects.

  14. Effects of exercise under hypoxic condition: Influence of different types of muscle contraction

    Grant number:17H02155  2017.4 - 2020.3

    GOTO KAZUSHIGE

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    Both cycling exercise and running exercise augmented carbohydrate metabolism compared with the same exercise in normoxia. Moreover, endurance exercise in hypoxia promoted muscle metabolism (muscle oxygen consumption). The findings from the present results suggest that endurance exercise in hypoxia facilitated carbohydrate metabolism with being independent of exercise modality (muscle contraction type).

  15. Effects of respiratory muscle activation and cardiopulmonary baroreflex on cardiovascular regulation during exercise(Fostering Joint International Research)

    Grant number:16KK0201  2017 - 2019

    Fund for the Promotion of Joint International Research (Fostering Joint International Research)

    Katayama Keisho

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    Grant amount:\13390000 ( Direct Cost: \10300000 、 Indirect Cost:\3090000 )

    Work of breathing influences sympathetic vasomotor outflow during exercise. The subjects performed leg cycling at 40%, 60%, and 80% peak workload. At 60% and 80% cycling, proportional assist ventilator reduced work of breathing and muscle sympathetic nerve activity (MSNA). Lowering the normally occurring work of breathing during exercise results in commensurate reductions in MSNA. These results provide evidence of a sympathetically mediated vasoconstrictor effect emanating from respiratory muscles during whole body exercise.
    Cardiopulmonary baroreflex control of sympathetic vasomotor outflow during exercise. MSNA was recorded during postexercise ischemia (PEI) after low- (PEI-L) and high- (PEI-H) intensity isometric exercise. PEI-L with leg cycling induced a significant decrease in MSNA, while PET-H with leg cycling did not decrease MSNA. These results suggest that cardiopulmonary baroreflex control of sympathetic vasomotor ouflow is attenuated by high metaboreflex activation.

  16. Developments of high-intensity intermittent training under hypoxic conditions for improving cardiovascular and metabolic risk maker

    Grant number:16H03234  2016.4 - 2019.3

    OGITA Futoshi

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    The present study aimed to clarify the effects of various high-intensity intermittent training (HIIT) under hypoxic conditions on cardiovascular and metabolic risk makers. In this study, 4 types of HIIT were done under 2500m above sea level. Those protocols were as follows; 1) six 10s-bout at 220%VO2max with 10s rest, 2) ten 20s-bout at 150%VO2max with 40s rest, 3)ten 1min-bout at 100%VO2max x 10 with 1min rest, 4) six or exhaustive 15s-bout at 175%VO2max with 10s rest. Each training was done 4 days a week for 4 weeks. As the results, HIIT (Tr.1 to 3) that the subjects did not reach exhaustion did not improve any factors, but that exhaustive HIIT (Tr.4) improved significantly cardiovascular function and body composition. Our results suggest that it is very beneficial and effective to perform exhaustive HIIT to improve effectively cardiovascular and metabolic risk factors. In other words, inexhaustive HIIT would be less effective even though it is done under hypoxic conditions.

  17. Effect of respiratory muscle activation on cardiovascular regulation during exericse

    Grant number:15H03079  2015.4 - 2018.3

    Keisho Katayama

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    Grant amount:\16250000 ( Direct Cost: \12500000 、 Indirect Cost:\3750000 )

    In this study, we attempted to clarify the effects of respiratory muscle activation on cardiovascular regulation. Study 1: Significant increases in arterial blood pressure and sympathetic vasomotor outflow appeared during exercise with expiratory resistance. Study 2: The increase in arterial blood pressure (ABP) during hyperpnoea was lower in young men compared to men. Study 3: During leg cycling with inspiratory resistive breathing, sympathetic vasomotor outflow was increased, accompanied by an increase in ABP. Young women, compared with age-matched men, had less of an increase in ABP. These results suggest that the attenuated inspiratory muscle-induced metaboreflex during exercise in young women could be attributed, in part, to a lesser sympathetic vasomotor outflow.

  18. Cardiorespiratory responses during active and passive exercise using a tandem-bicycle ergometer

    Grant number:15K01509  2015.4 - 2018.3

    Onodera Sho

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    The purpose of this study was to clarify cardiorespiratory responses to active and passive exercise using tandem bicycle ergometer. As a result, oxygen uptake and heart rate responses to passive pedaling exercise, which was determined using our tandem bicycle ergometer, increased significantly in the number of pedal rotations. These data suggest that passive pedaling exercise using our tandem ergometer could be applied to the rehabilitation for the people exercise that is not able to do voluntarily exercise.

  19. The effects of exercise under hypoxia on cognitive function

    Grant number:15K12664  2015.4 - 2017.3

    ANDO SOICHI

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    The purpose of this study was to examine the combined effects of acute exercise and severe hypoxia on cognitive function. The participants completed cognitive tasks at rest and during moderate exercise under either normoxic or severe hypoxic conditions. Cognitive performance improved during exercise under both normoxia and hypoxia, without sacrificing accuracy. However, under hypoxia, cognitive improvements were attenuated for individuals exhibiting a greater decrease in arterial oxygen saturation. The present results suggest that arterial desaturation and resultant biological processes attenuate cognitive improvements during exercise under hypoxia.

  20. Effect of respiratory muscle training in hypoxia on endurance exercise performance

    Grant number:26560348  2014.4 - 2017.3

    Katayama Keisho

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    Grant amount:\3640000 ( Direct Cost: \2800000 、 Indirect Cost:\840000 )

    The purpose of the present study was to clarity the effect of respiratory muscle endurance training in hypoxia on respiratory muscle-induce metaboreflex. Collegiate male endurance runners assigned to a normoxic or hypoxic group. Before and after 6 weeks of respiratory muscle endurance training, cardiovascular response to an incremental respiratory endurance test was measured. Minute ventilation during the training increased progressively. Target SpO2 in the hypoxic group set at 80%. The change arterial blood pressure during the incremental respiratory endurance test reduced significantly after the training in both groups. No significant difference in arterial blood pressure during hyperpnoea was found after the training between the two groups. These results suggest respiratory muscle-induced metaboreflex is attenuate by respiratory muscle endurance training, but no additional effect appears when the training is performed under hypoxic conditions.

  21. Effects of exrecise training in hypoxia on glucome metabolism

    Grant number:26282180  2014.4 - 2017.3

    GOTO KAZUSHIGE

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    The present study determined influence of exercise in hypoxia on glucose metabolism. The findings from experiments over 3 years indicated that exercise, including pedaling exercise, running exercise, was effective for promoting glucose metabolism. Moreover, augmented glucose metabolism by exercise in hypoxia was commonly observed in athletes, normal people and obese people. Furthermore, exercise in hypoxia did not promote exercise-induced muscle damage and inflammatory responses, and oxidation stress compared with the same exercise in normoxia. However, exercise in hypoxia did not affect acutely glucose tolerance or insulin sensitivity after the exercise.

  22. Development of a screening test to predict acute mountain sickness

    Grant number:26560349  2014.4 - 2017.3

    Ishida Koji

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    In order to develop a screening test to predict who is more likely to suffer from acute mountain sickness (AMS), we examined the cardio-respiratory responses to acute and gradual (1%/min) decrease in inspired oxygen content (12-13%) during middle intensity (35-40%max) exercise at sea level and compared these between the subjects who had suffered and not suffered from AMS at high altitude. We recruited two subjects’ group, one was the university students who had climbed the same high mountain (3000m) and the other was the middle-aged and elderly who have well experienced in high mountains above 2500m. The results suggested that we had better adopt the gradual hypoxic protocol based on subjects’ comfort and safety, and that people whose arterial oxygen saturation falls rapidly and below 75% during hypoxic exercise, or whose minute ventilation and end-tidal CO2 partial pressure at each stage show lower and higher value respectively should be susceptible to AMS at high altitude.

  23. Effect of food, time, exercise type and intensity on exhaled acetone during exercise

    Grant number:25350812  2013.4 - 2016.3

    Nagamine Koichiro

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    Acetone is produced in lipolysis, and exhausted with exhaled air and urine. Therefore, acetone contained in the exhaled air is expected to be an indicator of lipolysis in our body. The purpose of this study was to examine the effect of various factors such as meal intake on the expired acetone and blood components during and after exercise by several exercise experiments.
    In all conditions, expired acetone significantly increased during or after exercise compared to before exercise. Judging from variations in blood components, lipolysis and production of acetone in their bodies were promoted by exercise. However, the differences about variation in expired acetone were observed by several factors such as meal after exercise, exercise intensity, combination of different types of exercise.
    In conclusion, acetone contained in the exhaled air might be useful as the indicator of lipolysis, if we adequately consider the conditions about exercise and meal.

  24. A developmental and practical study of the tandem-bicycle ergometer

    Grant number:24500686  2012.4 - 2015.3

    ONODERA Sho

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    Authorship:Coinvestigator(s) 

    We developed the tandem-bicycle ergometer. It verified that cardiorespiratory responses to submaximal exercise are the same between front and rear saddles. Thus it is clear that the tandem-bicycle ergometer has the same function as between front and rear saddles.

  25. Effect of exercise habit on cardiovascular and cerebral blood flow regulations: a fundamental research for preventing brain disease

    Grant number:24300237  2012.4 - 2015.3

    OGOH Shigehiko

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    Authorship:Coinvestigator(s) 

    In our country, it has been reported that 10% of elderly who is more than 65 years old, is Dementia. Recently, epidemiological studies suggest that chronic exercise training or exercise habit decreases a risk of cerebral disease including dementia. Therefore, for many researchers it is worthy to note the relationship between cerebral disease and exercise habit. However, cerebral circulation has some complicated physiological mechanisms, thus, we do not have any physiological evidences of the effect of chronic exercise training on preventing cerebral disease. In the present research project, as a fundamental study in this research area, we demonstrated new findings about the adaptation of cerebral blood flow regulation system related to cerebral disease to chronic exercise. In addition, we found the relationship between systemic circulatory or respiratory regulation system and cerebral circulatory system in this project.

  26. Effect of respiratory system on circulatory regulation during exercise

    Grant number:24300222  2012.4 - 2015.3

    KATAYAMA KEISHO

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    Authorship:Principal investigator 

    Grant amount:\18330000 ( Direct Cost: \14100000 、 Indirect Cost:\4230000 )

    It has been thought that an increase in respiratory muscle activity affects cardiovascular regulation during exercise. We found that an enhancement of inspiratory muscle work causes an increase in sympathetic vasomotor outflow with a corresponding enhancement of arterial blood pressure during exercise. An enhancement of inspiratory muscle activity under hypoxic condition leads to large increases in sympathetic vasomotor outflow and BP. It is possible that this large vasoconstrictor activity reduces blood flow and oxygen transport to the working limb, thereby exacerbating limb fatigue and compromising exercise performance.

  27. Clarification of the effective way of breathing and its mechanism during aerobic exercise

    Grant number:23500777  2011 - 2013

    ISHIDA Koji

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    This study revealed that (1) repeated and exaggerated ventilation during exercise produced by short term aerobic training combined with chest wall restriction or inhalation of hypoxic gas, reinforced subsequent ventilatory response to normal exercise, indicating that learning should be involved in the respiratory control during exercise, and that (2) high intensity cycle exercise often induced a locomotor-respiratory coupling and resultant easiness during exercise, while during moderate intensity cycle exercise which was often used in aerobic exercise, there was no difference in cardio-respiratory responses between coupling and non-coupling so that the locomotor-respiratory coupling should have no beneficial effect on moderate intensity exercise. These results suggest that during aerobic exercise, we should keep in mind to breathe slowly rather than to synchronize respiration to locomotion, and that appropriate breathing way during exercise could be obtained from repetitive learning.

  28. The interaction between respiratory and cardiovascular regulations during exercise

    Grant number:22700649  2010 - 2011

    KATAYAMA Keisho

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    Authorship:Principal investigator 

    Grant amount:\4160000 ( Direct Cost: \3200000 、 Indirect Cost:\960000 )

    The purpose of the present study was to elucidate 1) whether carotid chemoreceptors affects muscle sympathetic nerve activity and cardiovascular responses during exercise, and 2) the influence of inspiratory muscle fatigue on muscle sympathetic nerve activity and blood pressure.
    Study 1 : Muscle sympathetic nerve activity(MSNA), cardiovascular variables, and plasma norepinephrine(NE) concentrations were measured during leg cycling at 40% and 60% of peak oxygen uptake(V. O2_<peak>) while breathing hypoxic gas mixture. MSNA during exercise in hypoxia was higher than in normoxia. These results suggest that acute hypoxia augments muscle neural activation during dynamic leg exercise, and that the MSNA response during exercise in hypoxia could be different from the change in plasma NE concentrations.
    Study 2 : MSNA and cardiovascular parameters were recorded during dynamic leg cycling at 40% V. O2_<peak> with or without inspiratory resistive breathing. The time-dependent increase in MSNA appeared during exercise with inspiratory resistive breathing, accompanied by an augmentation of blood pressure(BP). These results suggest that inspiratory muscle fatigue induces increases in muscle sympathetic vasomotor ouflow and BP during dynamic exercise.

  29. EFFECTS OF PHYSICAL EXERCISE TRAINING ON NEURAL AND HUMORAL SYSTEMS FOR CARDIOVASCULAR REGULATION

    Grant number:21300239  2009 - 2011

    SAITO Mitsuru

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    Endurance exercise training decreases resting blood pressure and increases blood flow distribution to skeletal muscles during exercise. To reveal the mechanisms of an adaptive change in cardiovascular regulation associated exercise training, muscle sympathetic nerve activity and catecholamine as neural and humoral factors were measured during submaximal exercise in endurance trained and untrained subjects. Sympathetic neural responses were greater in the trained than in the untrained group. However, the response of the humoral factors was the same in both groups. These results indicate that an effect of the exercise training on neural and humoral responses for cardiovascular regulatory mechanisms is not identical.

  30. Study on the effectiveness of diet or exercise therapy for young obese males in terms of insulin resistance.

    Grant number:21500682  2009 - 2011

    KOIKE Teruhiko

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    Appropriate lifestyle choices when persons are young and healthy are critical for the maintenance of life-long health in an ageing society. In the present study, diet and exercise habits surveyed among young obese males showed various characteristics. However, each individual had different lifestyle-related problems, which would demand individualized measures. Caloric restriction with exercise for 4 weeks strongly suppressed insulin resistance and chronic inflammatory status, but the effects were weaker by caloric restriction alone, indicating importance of exercise to enhance metabolic benefits with diet therapy.

  31. Respiratory and cardiovascular regulations during exercise in hypoxia

    Grant number:20700523  2008 - 2009

    KATAYAMA Keisho

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    Authorship:Principal investigator 

    Grant amount:\4420000 ( Direct Cost: \3400000 、 Indirect Cost:\1020000 )

    The purpose of the present study was to elucidate respiratory and cardiovascular responses at rest and during exercise in hypoxia. Study 1 ; the subjects breathed hypoxic gas mixture (12%O2) for 20 min. Flow-mediated vasodilation (FMD) was measured before and after hypoxic exposure. FMD was increased after acute hypoxia, suggesting that acute hypoxic exposure could improve endothelial function. Study 2 ; the subjects performed cycle exercise at 40% and 70% of maximal exercise intensity in normoxia (21%O2) and hypoxia (12.7%O2). Arterial blood pressure and muscle sympathetic nerve activity during exercise in hypoxia (hypoxic condition) differed from those in normoxia. These results suggest that arterial oxygenation could affect arterial blood pressure regulation during exercise.

  32. The effect of training on physical capacity during unilateral limb unloading in humans

    Grant number:17300207  2005 - 2008

    HIROSHI Akima

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    Authorship:Coinvestigator(s) 

  33. 低酸素暴露に対する身体適応の反復効果

    Grant number:17700488  2005 - 2006

    片山 敬章

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    Authorship:Principal investigator 

    Grant amount:\3700000 ( Direct Cost: \3700000 )

    我々のこれまでの研究結果から,1日1時間程度の間欠的な常圧低酸素環境への暴露により,高度4,300m以上,いわゆる高高所を模擬した環境においては,運動時の換気応答の増加が認められ,この増加が動脈血酸素飽和度(SaO2)の改善に貢献することが明らかにされている.これらの結果から,1日数時間程度の間欠的低酸素暴露により,高高所での高山病の軽減やパフォーマンス向上が推測される.しかしながら,この間欠的低酸素暴露がいわゆる準高所と呼ばれる高度2,500m程度における低酸素環境下での運動時の呼吸循環応答に及ぼす影響については不明である.そこで,本年度の研究では,短期間の間欠的低酸素暴露が,準高所を模擬した環境における運動時の呼吸循環応答を明らかにすることを目的とした.被験者は健康な男性21名とした(低酸素群14名,対象群7名).低酸素群をさらに酸素濃度の異なる2群に振り分けた:低酸素群1(7名),低酸素群2(7名).間欠的低酸素暴露には,低酸素テントを使用し,低酸素制御装置からの酸素濃度は低酸素群1では15.5%,低酸素群2では12.3%に設定した.1日の暴露時間は1時間,期間を7日間とした.7日間の間欠的低酸素暴露前後に15.5%の酸素ガスを吸入(高度2,500mを模擬)させ,安静時及び運動時の呼吸循環応答の測定を実施した.また,安静時において低酸素換気応答(HVR)を測定した.低酸素群2において,HVRの有意な増加が間欠的低酸素暴露後に認められたが,低酸素群1及び対照群では変化は見られなかった.高度2,500を模擬した15.5%酸素吸入による運動時の換気量及びSaO2にはすべての群において有意な変化は認められなかった.これらの結果から,短期間の間欠的低酸素暴露による低酸素換気感受性の変化は,準高所における運動時の換気応答に影響を及ぼさないことが示唆される.

  34. 間欠的な低酸素暴露による運動効率の改善に関する研究

    Grant number:15700413  2003 - 2004

    片山 敬章

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    Authorship:Principal investigator 

    Grant amount:\3500000 ( Direct Cost: \3500000 )

    間欠的低酸素暴露による最大下運動時の呼吸循環応答ならびに持久的パフォーマンスの変化を明らかにするために,以下の実験を実施した.
    実験1)被験者を15名の持久的鍛練者とした(低酸素群8名,コントロール群7名).低酸素暴露:には簡易式低酸素テントを用い(酸素濃度:約12%)時間及び期間は3時間/日,2週間とした.間欠的低酸素暴露前後に最大及び最大下運動テスト,3,000mタイムトライアルを実施した.2週間の間欠的低酸素暴露後,最大運動テストにおける呼吸循環応答は両群共に変化が認められなかった.低酸素群では,最大下運動時に酸素摂取量及び心拍数の有意な低下が認められた.3000mランニングタイムは,低酸素群で向上傾向が認められたが統計的に有意な差は認められなかった.各個人の最大下運動時における酸素摂取量の変化と3000mランニングタイムの変化との関係を見るために,それぞれの変化値(Δ)を求め,単純相関にてそれぞれの関係を求めた.その結果,最大下運動時の酸素摂取量の変化と3000mランニングタイムとの間に有意な相関関係が見られた.これらの結果から,間欠的低酸素暴露による持久的パフォーマンス向上に運動時の酸素摂取量の低下が寄与することが示唆された.
    実験2)被検者を13名の持久的鍛錬者とし,低酸素群6名,コントロール群7名とした.低酸素暴露の方法は実験1と同様とし,時間を3時間/日,期間を1週間とした.間欠的低酸素暴露前後に最大及び最大下運動テストを実施した.1週間の間欠的低酸素暴露後,最大及び最大下運動時における呼吸循環応答には両群共に変化が認められなかった.これらの結果から,3時間/日,1週間の間欠的低酸素暴露では運動時の呼吸循環応答に影響を及ぼさないことが明らかとなった.

  35. 高齢者の呼気中一酸化窒素および亜酸化窒素濃度に関する研究

    Grant number:13878007  2001 - 2002

    萌芽研究

    宮村 実晴

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    Authorship:Coinvestigator(s) 

    平成14年度では、先の平成13年度において日常生活で規則的な身体運動(大極拳、テニス)を行っている中高齢者で得られた研究成果を踏まえ、愛知県および宮山県の高齢者を対象に、呼気中一酸化窒素および亜酸化窒素濃度と体力あるいは日常生活における身体運動能力とどのような関係を有するかを明らかにしようとした。
    被験者は愛知県老人ホーム入所者および富山県庄川町に在住する65歳以上の健康な高齢者73名である。各被験者を対象に安静時の呼気ガスを採集し、呼気中一酸化窒素および亜酸化窒素濃度を測定した。アンケート調査により各被験者の日常生活における身体運動を把握する、と同時に運動能力(シャトルウオーク、筋力、柔軟性、反応時間、開眼片足立ち、閉眼片足立ち)を測定した。
    その結果、握力、全身反応時間、単純反応時間、開眼片足立ちおよび閉眼片足立ちは、庄川町の高齢者の方が老人ホームの高齢者のそれよりよい成績(p<0.05)であった。また呼気中の一酸化窒素濃度も庄川町の高齢者の方が老人ホームの高齢者のそれより高かった(p<0.05)。一方、年齢と開眼片足立ち(r=-0.29)、ファンクショナルリーチ(r=-0.29)、シャトルウオーク(r=-0.31)とそれぞれ有意の相関関係が認められた。
    アンケート調査による日常生活における身体活動量は、庄川町の高齢者の方が老人ホームの高齢者と比べ、できるだけ歩く、畑仕事をする、運動教室にでかける、など日常生活において自身の体を使うよう心掛けていることが明らかとなった。
    以上の結果は、持久性能力(体力)あるいは運動能力は加齢と共に低下するが、体力の低下は日常生活における身体活動量に影響されることを示唆するものである。なお、庄川町の高齢者における呼気中の一酸化窒素濃度が老人ホームの高齢者のそれより何故高かったか、また呼気中の一酸化窒素濃度と体力との関係については今後の検討課題である。

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Teaching Experience (On-campus) 3

  1. 基礎医科学実習 ベーシックトレーニング

    2020

  2. 医科学セミナー

    2020

  3. 健康運動科学実験研究

    2020

Teaching Experience (Off-campus) 3

  1. 個人スポーツI, II

    2015.4 Chukyo University)

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    Level:Undergraduate (liberal arts) 

  2. 運動生理学

    2013.4 Sugiyama Jogakuen University)

  3. 運動生理学研究IV

    2009.4 - 2020.3 Chukyo University)

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    Level:Postgraduate