研究者詳細 - 島田　聡子

写真a

シマダ　サトコ

島田　聡子

SHIMADA, Satoko

所属

医学部附属病院病理部病院助教

学位 1

医学博士（名古屋大学）

学位の先頭へ▲

研究分野 1

その他 / その他 / 人体病理学

研究分野の先頭へ▲

現在の研究課題とSDGs 1

診断病理学

現在の研究課題とSDGsの先頭へ▲

学歴 1

名古屋大学医学部医学科

1995年4月 - 2001年3月

学歴の先頭へ▲

論文 37

Clinicopathological characteristics associated with the engraftment of patient lymphoma cells in NOG mice

Sahashi, S; Shimada, K; Takagi, Y; Aoki, T; Kunou, S; Sakamoto, A; Murase, A; Furukawa, K; Kagaya, Y; Yamaga, Y; Takai, M; Tokuyama, K; Shimada, S; Nakamura, S; Kiyoi, H

INTERNATIONAL JOURNAL OF HEMATOLOGY 118 巻 ( 2 ) 頁： 221 - 230 2023年8月

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記述言語：英語出版者・発行元：International Journal of Hematology

Patient-derived xenograft (PDX) mouse models are useful for deepening our understanding of the biology of malignant lymphoma; however, factors associated with the success of the PDX lymphoma model are largely unknown. We retrospectively analyzed the characteristics of 66 xenotransplantations from 65 patients. In all, 43 (65%) specimens were obtained from patients aged > 60 years, and 42 (64%) specimens were obtained at diagnosis. Specimens were obtained from patients with the following diseases: diffuse large B-cell lymphoma (n = 30), intravascular large B-cell lymphoma (n = 12), follicular lymphoma (n = 8), peripheral T-cell lymphoma (n = 7), mantle cell lymphoma (n = 2), and other (n = 7). The specimens were sourced mainly from bone marrow (n = 31, 47%) and extranodal tumors (n = 13, 20%). Engraftment was successful in 33/66 (50%) xenotransplantations. The median age of patients who provided successful specimens was significantly higher than that for unsuccessful specimens (p = 0.013). Specimens with a high proportion of tumor cells in the graft and those obtained from patients with relapsed/refractory disease showed higher tendencies toward successful engraftment. Taken together, these data suggest that tumor cells with a highly malignant potential might have a high likelihood of engraftment.

DOI： 10.1007/s12185-023-03604-z

Web of Science

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PubMed
Two cases of solitary fibrous tumor/hemangiopericytoma with different clinical features according to the World Health Organization classification: case report and review of the literature.

Nishii T, Nagashima Y, Nishimura Y, Ito H, Oyama T, Matsuo M, Sakakibara A, Shimada S, Saito R

Journal of spine surgery (Hong Kong) 7 巻 ( 4 ) 頁： 532 - 539 2021年12月

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記述言語：英語

DOI： 10.21037/jss-21-83

PubMed
Exosomes secreted from cancer-associated fibroblasts elicit anti-pyrimidine drug resistance through modulation of its transporter in malignant lymphoma

Kunou Shunsuke, Shimada Kazuyuki, Takai Mika, Sakamoto Akihiko, Aoki Tomohiro, Hikita Tomoya, Kagaya Yusuke, Iwamoto Eisuke, Sanada Masashi, Shimada Satoko, Hayakawa Fumihiko, Oneyama Chitose, Kiyoi Hitoshi

ONCOGENE 40 巻 ( 23 ) 頁： 3989 - 4003 2021年6月

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記述言語：日本語出版者・発行元：Oncogene

The tumor microenvironment is deeply involved in the process of tumor growth and development. In this study, we focused on cancer-associated fibroblasts (CAFs) and their derived exosomes on the lymphoma microenvironment to uncover their clinical significance. CAFs were established from primary lymphoma samples, and exosomes secreted from CAFs were obtained by standard procedures. We then investigated the roles of CAFs and their derived exosomes in the survival and drug resistance of lymphoma cells. CAFs supported the survival of lymphoma cells through increased glycolysis, and the extent differed among CAFs. Exosomes were identified as a major component of the extracellular vesicles from CAFs, and they also supported the survival of lymphoma cells. The suppression of RAB27B, which is involved in the secretion of exosomes, using a specific siRNA resulted in reduced exosome secretion and decreased survival of lymphoma cells. Moreover, anti-pyrimidine drug resistance was induced in the presence of exosomes through the suppression of the pyrimidine transporter, equilibrative nucleoside transporter 2 (ENT2), and the suppression of ENT2 was significant in in vivo experiments and clinical samples. RNA sequencing analysis of miRNAs in exosomes identified miR-4717-5p as one of the most abundant miRNAs in the exosome, which suppressed the expression of ENT2 and induced anti-pyrimidine drug resistance in vitro. Our results suggest that exosomes including miR-4717-5p secreted from CAFs play a pivotal role in the lymphoma microenvironment, indicating that they are a promising therapeutic target.

DOI： 10.1038/s41388-021-01829-y

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PubMed
The Positivity of Phosphorylated STAT3 Is a Novel Marker for Favorable Prognosis in Germinal Center B-Cell Type of Diffuse Large B-Cell Lymphoma

Morichika Kazuho, Karube Kennosuke, Sakihama Shugo, Watanabe Risa, Kawaki Mamoru, Nishi Yukiko, Nakachi Sawako, Okamoto Shiki, Takahara Taishi, Satou Akira, Shimada Satoko, Shimada Kazuyuki, Tsuzuki Toyonori, Fukushima Takuya, Morishima Satoko, Masuzaki Hiroaki

AMERICAN JOURNAL OF SURGICAL PATHOLOGY 45 巻 ( 6 ) 頁： 832 - 840 2021年6月

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記述言語：日本語出版者・発行元：American Journal of Surgical Pathology

On the basis of immunohistochemistry, diffuse large B-cell lymphoma (DLBCL) is categorized as a germinal center B-cell (GCB) or non-GCB subtype. Recent integrated genomic analyses have highlighted the importance of the JAK-STAT3 pathway in the molecular pathogenesis of DLBCL. However, its relevance to clinical outcomes remains controversial. Therefore, we evaluated the extent of the nuclear expression of phosphorylated STAT3 (pSTAT3), a surrogate marker of signal transducer and activator of transcription 3 (STAT3) activation, by immunohistochemistry. We also analyzed the potential relationship between pSTAT3 positivity (defined as ≥ 40% positive neoplastic cells) and clinicopathologic characteristics in 294 patients with DLBCL. pSTAT3 was detected in 122 patients (42%), with a higher rate in the non-GCB subtype than in the GCB subtype (57% vs. 28%, P < 0.001). Factors potentially activating STAT3, MYD88L265P, and Epstein-Barr virus-encoded small RNA were identified in the pSTAT3-positive non-GCB subtype, whereas the pSTAT3-positive GCB subtype often showed STAT3 mutations and lacked EZH2 mutations and the rearrangements of BCL2 and MYC. Multivariate analyses revealed that the pSTAT3-positive GCB subtype showed a favorable prognosis (HR: 0.17; 95% confidence interval, 0.04-0.7; P = 0.014). These findings suggest that pSTAT3 positivity may have a unique impact on the clinicopathologic characteristics of DLBCL, making it a promising novel marker for the favorable prognosis of patients with the GCB subtype.

DOI： 10.1097/PAS.0000000000001691

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PubMed
Frequent genetic alterations in immune checkpoint-related genes in intravascular large B-cell lymphoma.

Shimada K, Yoshida K, Suzuki Y, Iriyama C, Inoue Y, Sanada M, Kataoka K, Yuge M, Takagi Y, Kusumoto S, Masaki Y, Ito T, Inagaki Y, Okamoto A, Kuwatsuka Y, Nakatochi M, Shimada S, Miyoshi H, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Shiozawa Y, Nannya Y, Okabe A, Kohno K, Atsuta Y, Ohshima K, Nakamura S, Ogawa S, Tomita A, Kiyoi H

Blood 137 巻 ( 11 ) 頁： 1491 - 1502 2021年3月

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出版者・発行元：Blood

DOI： 10.1182/blood.2020007245

Scopus

PubMed
Unusual presentation of recurrent follicular lymphoma as diffuse granular shadow

Ito Takayasu, Okachi Shotaro, Ishikawa Yuichi, Shimada Satoko, Wakahara Keiko, Hashimoto Naozumi

RESPIROLOGY CASE REPORTS 9 巻 ( 3 ) 頁： e00710 2021年3月

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出版者・発行元：Respirology Case Reports

DOI： 10.1002/rcr2.710

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PubMed
Diagnostic utility of programmed cell death ligand 1 (clone SP142) immunohistochemistry for malignant lymphoma and lymphoproliferative disorders: A brief review

Sakakibara Ayako, Kohno Kei, Ishikawa Eri, Suzuki Yuka, Tsuyuki Yuta, Shimada Satoko, Shimada Kazuyuki, Satou Akira, Takahara Taishi, Ohashi Akiko, Takahashi Emiko, Kato Seiichi, Nakamura Shigeo, Asano Naoko

JOURNAL OF CLINICAL AND EXPERIMENTAL HEMATOPATHOLOGY 61 巻 ( 4 ) 頁： 182 - 191 2021年

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記述言語：日本語出版者・発行元：日本リンパ網内系学会

DOI： 10.3960/jslrt.21003

Web of Science

PubMed

CiNii Research
Lymphocyte-depleted classic Hodgkin lymphoma with primary extranodal disease: Two cases that highlight the combination of immunodeficiency and immune escape in the pathogenesis

Tsuyuki Yuta, Kohno Kei, Inagaki Yuichiro, Sakai Yu, Kosugi Hiroshi, Takahashi Emiko, Suzuki Yuka, Shimada Satoko, Kato Seiichi, Takahara Taishi, Satou Akira, Shimoyama Yoshie, Nakamura Shigeo, Asano Naoko, Sakakibara Ayako

JOURNAL OF CLINICAL AND EXPERIMENTAL HEMATOPATHOLOGY 61 巻 ( 3 ) 頁： 173 - 179 2021年

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記述言語：日本語出版者・発行元：日本リンパ網内系学会

DOI： 10.3960/jslrt.21008

Web of Science

PubMed

CiNii Research
Age-related EBV-associated B-cell lymphoproliferative disorders and other EBV plus lymphoproliferative diseases: New insights into immune escape and immunodeficiency through staining with anti-PD-L1 antibody clone SP142

Sakakibara Ayako, Kohno Kei, Ishikawa Eri, Suzuki Yuka, Shimada Satoko, Eladl Ahmed E., Elsayed Ahmed A., Daroontum Teerada, Satou Akira, Takahara Taishi, Ohashi Akiko, Takahashi Emiko, Kato Seiichi, Nakamura Shigeo, Asano Naoko

PATHOLOGY INTERNATIONAL 70 巻 ( 8 ) 頁： 481 - 492 2020年8月

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記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Pathology International

DOI： 10.1111/pin.12946

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PubMed
PD-L1 (SP142) expression in neoplastic cells predicts a poor prognosis for patients with intravascular large B-cell lymphoma treated with rituximab-based multi-agent chemotherapy

Suzuki Yuka, Kohno Kei, Matsue Kosei, Sakakibara Ayako, Ishikawa Eri, Shimada Satoko, Shimada Kazuyuki, Mabuchi Seiyo, Takahara Taishi, Kato Seiichi, Nakamura Shigeo, Satou Akira

CANCER MEDICINE 9 巻 ( 13 ) 頁： 4768 - 4776 2020年7月

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記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Cancer Medicine

DOI： 10.1002/cam4.3104

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PubMed
Rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone combined with high-dose methotrexate plus intrathecal chemotherapy for newly diagnosed intravascular large B-cell lymphoma (PRIMEUR-IVL): a multicentre, single-arm, phase 2 trial

Shimada Kazuyuki, Yamaguchi Motoko, Atsuta Yoshiko, Matsue Kosei, Sato Keijiro, Kusumoto Shigeru, Nagai Hirokazu, Takizawa Jun, Fukuhara Noriko, Nagafuji Koji, Miyazaki Kana, Ohtsuka Eiichi, Okamoto Masataka, Sugita Yasumasa, Uchida Toshiki, Kayukawa Satoshi, Wake Atsushi, Ennishi Daisuke, Kondo Yukio, Izumi Tohru, Kin Yoshihiro, Tsukasaki Kunihiro, Hashimoto Daigo, Yuge Masaaki, Yanagisawa Atsumi, Kuwatsuka Yachiyo, Shimada Satoko, Masaki Yasufumi, Niitsu Nozomi, Kiyoi Hitoshi, Suzuki Ritsuro, Tokunaga Takashi, Nakamura Shigeo, Kinoshita Tomohiro

LANCET ONCOLOGY 21 巻 ( 4 ) 頁： 593 - 602 2020年4月

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記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：The Lancet Oncology

DOI： 10.1016/S1470-2045(20)30059-0

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PubMed
Diagnostic utility of programmed cell death ligand 1 (clone SP142) in mediastinal composite lymphoma: A report of two cases

Sakakibara Ayako, Kohno Kei, Iwakoshi Akari, Moritani Suzuko, Fujishiro Aya, Kito Katsuyuki, Suzuki Yuka, Shimada Satoko, Nakaguro Masato, Shimoyama Yoshie, Takahara Taishi, Takahashi Emiko, Ohashi Akiko, Satou Akira, Kato Seiichi, Asano Naoko, Nakamura Shigeo

PATHOLOGY INTERNATIONAL 70 巻 ( 2 ) 頁： 116 - 122 2020年2月

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記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Pathology International

DOI： 10.1111/pin.12891

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PubMed
Syncytial variant of classic Hodgkin lymphoma: Four cases diagnosed with the aid of CD274/programmed cell death ligand 1 immunohistochemistry

Kohno Kei, Sakakibara Ayako, Iwakoshi Akari, Hasegawa Masaki, Adachi Shiro, Ishikawa Eri, Suzuki Yuka, Shimada Satoko, Nakaguro Masato, Shimoyama Yoshie, Takahara Taishi, Takahashi Emiko, Ohashi Akiko, Satou Akira, Kato Seiichi, Asano Naoko, Nakamura Shigeo

PATHOLOGY INTERNATIONAL 70 巻 ( 2 ) 頁： 108-115 2020年2月

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記述言語：英語掲載種別：研究論文（学術雑誌）

DOI： 10.1111/pin.12888

Web of Science

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PubMed
Favorable Outcomes of Newly Diagnosed Intravascular Large B-Cell Lymphoma Patients Treated with R-CHOP Combined with High-Dose Methotrexate Plus Intrathecal Chemotherapy: Results from a Multicenter Phase 2 Trial (PRIMEUR-IVL)

Shimada Kazuyuki, Yamaguchi Motoko, Atsuta Yoshiko, Matsue Kosei, Sato Keijiro, Kusumoto Shigeru, Nagai Hirokazu, Takizawa Jun, Fukuhara Noriko, Nagafuji Koji, Miyazaki Kana, Ohtsuka Eiichi, Okamoto Masataka, Sugita Yasumasa, Uchida Toshiki, Kayukawa Satoshi, Wake Atsushi, Ennishi Daisuke, Kondo Yukio, Izumi Tohru, Kin Yoshihiro, Tsukasaki Kunihiro, Hashimoto Daigo, Yuge Masaaki, Yanagisawa Atsumi, Kuwatsuka Yachiyo, Shimada Satoko, Masaki Yasufumi, Niitsu Nozomi, Kiyoi Hitoshi, Suzuki Ritsuro, Tokunaga Takashi, Nakamura Shigeo, Kinoshita Tomohiro

BLOOD 134 巻 2019年11月

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DOI： 10.1182/blood-2019-126798

Web of Science
Divergence and heterogeneity of neoplastic PD-L1 expression: Two autopsy case reports of intravascular large B-cell lymphoma

Sakakibara Ayako, Inagaki Yuichiro, Imaoka Eiki, Sakai Yu, Ito Masafumi, Ishikawa Eri, Shimada Satoko, Shimada Kazuyuki, Suzuki Yuka, Nakamura Shigeo, Satou Akira, Kohno Kei

PATHOLOGY INTERNATIONAL 69 巻 ( 3 ) 頁： 148-154 2019年3月

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記述言語：英語掲載種別：研究論文（学術雑誌）

DOI： 10.1111/pin.12757

Web of Science

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PubMed
Immune evasion-related extranodal large B-cell lymphoma: A report of six patients with neoplastic PD-L1-positive extranodal diffuse large B-cell lymphoma

Suzuki Yuka, Sakakibara Ayako, Shimada Kazuyuki, Shimada Satoko, Ishikawa Eri, Nakamura Shigeo, Kato Seiichi, Takahara Taishi, Asano Naoko, Satou Akira, Kohno Kei

PATHOLOGY INTERNATIONAL 69 巻 ( 1 ) 頁： 13-20 2019年1月

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記述言語：英語掲載種別：研究論文（学術雑誌）

DOI： 10.1111/pin.12742

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PubMed
Immunohistochemical assessment of the diagnostic utility of PD-L1: a preliminary analysis of anti-PD-L1 antibody (SP142) for lymphoproliferative diseases with tumour and non-malignant Hodgkin-Reed-Sternberg (HRS)-like cells

Sakakibara Ayako, Kohno Kei, Eladl Ahmed E., Klaisuwan Teerada, Ishikawa Eri, Suzuki Yuka, Shimada Satoko, Nakaguro Masato, Shimoyama Yoshie, Takahara Taishi, Kato Seiichi, Asano Naoko, Nakamura Shigeo, Satou Akira

HISTOPATHOLOGY 72 巻 ( 7 ) 頁： 1156-1163 2018年6月

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記述言語：英語掲載種別：研究論文（学術雑誌）

DOI： 10.1111/his.13475

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PubMed
Anaplastic variant of diffuse large B-cell lymphoma with hallmark cell appearance: Two cases highlighting a broad diversity in the diagnostics

Sakakibara Ayako, Kohno Kei, Kuroda Naoto, Yorita Kenji, Megahed Nirmeen A., Eladl Ahmed E., Daroontum Teerada, Ishikawa Eri, Suzuki Yuka, Shimada Satoko, Nakaguro Masato, Shimoyama Yoshie, Satou Akira, Kato Seiichi, Yatabe Yasushi, Asano Naoko, Nakamura Shigeo

PATHOLOGY INTERNATIONAL 68 巻 ( 4 ) 頁： 251-255 2018年4月

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記述言語：英語掲載種別：研究論文（学術雑誌）

DOI： 10.1111/pin.12653

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PubMed
Autopsy case report of intravascular large B-cell lymphoma with neoplastic PD-L1 expression

Sakakibara Ayako, Inagaki Yuichiro, Imaoka Eiki, Ishikawa Eri, Shimada Satoko, Shimada Kazuyuki, Suzuki Yuka, Nakamura Shigeo, Satou Akira, Kohno Kei

JOURNAL OF CLINICAL AND EXPERIMENTAL HEMATOPATHOLOGY 58 巻 ( 1 ) 頁： 32-35 2018年

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記述言語：英語掲載種別：研究論文（学術雑誌）

DOI： 10.3960/jslrt.17037

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PubMed
Emetine elicits apoptosis of intractable B-cell lymphoma cells with MYC rearrangement through inhibition of glycolytic metabolism

Aoki Tomohiro, Shimada Kazuyuki, Sakamoto Akihiko, Sugimoto Keiki, Morishita Takanobu, Kojima Yuki, Shimada Satoko, Kato Seiichi, Iriyama Chisako, Kuno Shunsuke, Harada Yasuhiko, Tomita Akihiro, Hayakawa Fumihiko, Kiyoi Hitoshi

ONCOTARGET 8 巻 ( 8 ) 頁： 13085-13098 2017年2月

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記述言語：英語掲載種別：研究論文（学術雑誌）

DOI： 10.18632/oncotarget.14393

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PubMed
Epstein-Barr virus-positive cytotoxic T-cell lymphoma followed by chronic active Epstein-Barr virus infection-associated T/NK-cell lymphoproliferative disorder: a case report.

Kato S, Miyata T, Takata K, Shimada S, Ito Y, Tomita A, Elsayed AA, Takahashi E, Asano N, Kinoshita T, Kimura H, Nakamura S.

Hum Pathol. 44 巻 ( 12 ) 頁： 2849-52. 2013年

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記述言語：英語掲載種別：研究論文（学術雑誌）
An autopsy case of lymphomatosis cerebri showing pathological changes of intravascular large B-cell lymphoma in visceral organs.

Hishikawa N, Niwa H, Hara T, Hara K, Ito M, Shimada S, Yoshida M, Hashizume Y, Murakami N.

Neuropathology 31 巻 ( 6 ) 頁： 612-9. 2011年

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記述言語：英語掲載種別：研究論文（学術雑誌）
Comparative clinicopathological study of primary CNS diffuse large B-cell lymphoma and intravascular large B-cell lymphoma.

Imai H, Shimada K, Shimada S, Abe M, Okamoto M, Kitamura K, Kinoshita T, Shiraishi T, Nakamura S.

Pathol Int. 59 巻 ( 7 ) 頁： 431-7 2009年

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記述言語：英語掲載種別：研究論文（学術雑誌）
Nodal T/NK-cell lymphoma of nasal type: a clinicopathological study of six cases.

Takahashi E, Asano N, Li C, Tanaka T, Shimada K, Shimada S, Yoshino T, Kojima M, Hara K, Eimoto T, Nakamura S

Histopathology 52 巻 ( 5 ) 頁： 585-96 2008年

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記述言語：英語掲載種別：研究論文（学術雑誌）
後腹膜軟部腫瘍の１例

和佐潤志　西田佳弘　筑紫聡　紫藤洋二　下山芳江　島田聡子　長坂徹郎　中村栄男

東海骨軟部腫瘍 20 巻頁： 25-26 2008年

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記述言語：日本語掲載種別：研究論文（学術雑誌）
右側胸部軟部腫瘍の１例

細野幸三　西田佳弘　筑紫聡　紫藤洋二　島田聡子　下山芳江　長坂徹郎　中村栄男

東海骨軟部腫瘍 20 巻頁： 13-14 2008年

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記述言語：日本語掲載種別：研究論文（学術雑誌）
本邦におけるintravascular large B-cell lymphomaの臨床病理

島田聡子　中村栄男

annual review 2008 血液頁： 150-154 2008年

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記述言語：日本語掲載種別：研究論文（学術雑誌）
Substained Remission after Rituximab-containing Chemotherapy for Intravascular Large B-cell lymphoma 査読有り

K Shimada, H Kosugi, H Narimatsu, S Shimada, T Suzuki, M Ito, T Kinoshita, N Mori, T Naoe

Journal of Clinical and Experimental Hematopathology 48 巻頁： 25-28 2008年

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記述言語：英語掲載種別：研究論文（学術雑誌）
Evaluation of organ involvement in intravascular large B-cell lymphoma by 18F-fluorodeoxyglucose positron emission tomography.

Shimada K, Kosugi H, Shimada S, Narimatsu H, Koyama Y, Suzuki N, Yuge M, Nishibori H, Iwata Y, Nakamura S, Naoe T, Kinoshita T.

Int J Hematol. 88 巻 ( 2 ) 頁： 149-53. 2008年

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記述言語：英語掲載種別：研究論文（学術雑誌）
*Nestin expression as a new marker in malignant peripheral nerve sheath tumors 査読有り

Satoko Shimada, Toyonori Tsuzuki, Makoto Kuroda, Tetsuro Nagasaka, Kazuo Hara, Emiko Takahashi, Seijun Hayakawa, Kenzo Ono, Nagako Maeda, Naoyoshi Mori, Peter B. Illei

Pathology International 57 巻頁： 60-67 2007年

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担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）
Intracranial lesion of Erdheim-Chester disease 査読有り

Satoko Shimada, Kenzo Ono, Yoshio Hashizume, Masato Nakaguro, Yasuhiko Suzuki, Naoyoshi Mori

Human Pathology 38 巻頁： 950-954 2007年

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担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）
Fatal varicella infection in a girl with systemic lupus erythematosus after oral scyclovir prophylaxis. 査読有り

I Hirose, H Yahaguchi, D Inaguma, K Ono, S Shimada, J Kawada, K Shiraki, H Kimura

Eur J Pediatr 165 巻頁： 280-281 2006年

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記述言語：英語掲載種別：研究論文（学術雑誌）
TIA-1 expresion in hairy cell leukemia 査読有り

Naoyoshi Mori, Yoshiko Idate Murakami, Satoko Shimada, Sachiko Iwamizu-Watanabe, Yoriko Yamashita, Yuichi Hasegawa, Hiroshi Kojima, Toshiro Nagasawa

Modern Pathology 17 巻頁： 840-846 2004年

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記述言語：英語掲載種別：研究論文（学術雑誌）
腹腔内出血で発症したSegmental Arterial Mediolysis (SAM)の一例

島田聡子、池田耕介、森尚義

現代医学 51 巻頁： 503-507 2004年

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担当区分：筆頭著者記述言語：日本語掲載種別：研究論文（学術雑誌）
Malignant mesothelioma of the tunica vaginalis testis: a case with a predominant sarcomatous component. 査読有り

Satoko Shimada, Kenzo Ono, Yasuhiko Suzuki, Naoyoshi Mori

Pathology International 54 巻頁： 930-934 2004年

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担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）
Neuronal Nitric Oxide Synthase-Membrane Phospholipid Interactions 査読有り

Yasuo Watanabe, Masahiro Nishio, Satoko Hamaji, Yuji Hayashi, Yu Hu, Hiroyoshi Hidaka

Archives of Biochemistry and Biophysics 358 巻 ( 1 ) 頁： 68-73 1998年

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記述言語：英語掲載種別：研究論文（学術雑誌）
Inter-isoformal regulation of nitric oxide synthase through heteromeric dimerization 査読有り

Yasuo Watanabe, Masahiro Nishio, Satoko Hamaji, Hiroyoshi Hidaka

Biochimica et Biophysica Acta 1388 巻頁： 199-208 1998年

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記述言語：英語掲載種別：研究論文（学術雑誌）

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論文の先頭へ▲

MISC 5

Frequent genetic alterations in immune checkpoint-related genes in intravascular large B-cell lymphoma

Kazuyuki Shimada 1 2 , Kenichi Yoshida 3 , Yasuhiro Suzuki 1 4 , Chisako Iriyama 1 5 , Yoshikage Inoue 3 6 , Masashi Sanada 7 , Keisuke Kataoka 3 8 , Masaaki Yuge 9 , Yusuke Takagi 10 11 , Shigeru Kusumoto 12 , Yasufumi Masaki 13 , Takahiko Ito 14 , Yuichiro Inagaki 15 , Akinao Okamoto 5 , Yachiyo Kuwatsuka 16 , Masahiro Nakatochi 17 , Satoko Shimada 18 , Hiroaki Miyoshi 19 , Yuichi Shiraishi 20 , Kenichi Chiba 20 , Hiroko Tanaka 21 , Satoru Miyano 21 22 , Yusuke Shiozawa 23 , Yasuhito Nannya 3 , Asako Okabe 24 , Kei Kohno 18 19 , Yoshiko Atsuta 25 , Koichi Ohshima 19 , Shigeo Nakamura 18 , Seishi Ogawa 3 26 27 , Akihiro Tomita 1 5 , Hitoshi Kiyoi 1

blood 2021年3月
Unusual presentation of recurrent follicular lymphoma as diffuse granular shadow

Takayasu Ito 1 , Shotaro Okachi 1 , Yuichi Ishikawa 2 , Satoko Shimada 3 , Keiko Wakahara 1 , Naozumi Hashimoto 1

Respirol Case Rep 2021年3月
Age-related EBV-associated B-cell lymphoproliferative disorders and other EBV + lymphoproliferative diseases: New insights into immune escape and immunodeficiency through staining with anti-PD-L1 antibody clone SP142

Ayako Sakakibara 1 , Kei Kohno 1 , Eri Ishikawa 1 , Yuka Suzuki 1 , Satoko Shimada 1 , Ahmed E Eladl 2 , Ahmed A Elsayed 2 , Teerada Daroontum 3 , Akira Satou 4 , Taishi Takahara 4 , Akiko Ohashi 4 , Emiko Takahashi 4 , Seiichi Kato 5 , Shigeo Nakamura 1 , Naoko Asano 6

Pathol Int . 2020年8月
PD-L1 (SP142) expression in neoplastic cells predicts a poor prognosis for patients with intravascular large B-cell lymphoma treated with rituximab-based multi-agent chemotherapy

Yuka Suzuki 1 , Kei Kohno 1 , Kosei Matsue 2 , Ayako Sakakibara 1 , Eri Ishikawa 1 3 , Satoko Shimada 1 , Kazuyuki Shimada 4 , Seiyo Mabuchi 1 , Taishi Takahara 5 , Seiichi Kato 6 , Shigeo Nakamura 1 , Akira Satou 5

Cancer Med . 2020年7月
Rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone combined with high-dose methotrexate plus intrathecal chemotherapy for newly diagnosed intravascular large B-cell lymphoma (PRIMEUR-IVL): a multicentre, single-arm, phase 2 trial

Kazuyuki Shimada 1 , Motoko Yamaguchi 2 , Yoshiko Atsuta 3 , Kosei Matsue 4 , Keijiro Sato 5 , Shigeru Kusumoto 6 , Hirokazu Nagai 7 , Jun Takizawa 8 , Noriko Fukuhara 9 , Koji Nagafuji 10 , Kana Miyazaki 2 , Eiichi Ohtsuka 11 , Masataka Okamoto 12 , Yasumasa Sugita 13 , Toshiki Uchida 14 , Satoshi Kayukawa 15 , Atsushi Wake 16 , Daisuke Ennishi 17 , Yukio Kondo 18 , Tohru Izumi 19 , Yoshihiro Kin 20 , Kunihiro Tsukasaki 21 , Daigo Hashimoto 22 , Masaaki Yuge 23 , Atsumi Yanagisawa 3 , Yachiyo Kuwatsuka 24 , Satoko Shimada 25 , Yasufumi Masaki 26 , Nozomi Niitsu 27 , Hitoshi Kiyoi 28 , Ritsuro Suzuki 29 , Takashi Tokunaga 7 , Shigeo Nakamura 25 , Tomohiro Kinoshita 30

Lancet Oncol . 2020年4月

MISCの先頭へ▲

講演・口頭発表等 3

Wilms' tumor gene (WT1) exxpression in neurogenic and myogenic satcomas 国際会議

26th International Congress of the International Academy of Pathology (IAP)

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開催年月日： 2006年9月

記述言語：英語会議種別：ポスター発表
Nestin Expression in Malignant Peripheral Nerve Sheath Tumor (MPNST) and Other Soft Tissue Tumors 国際会議

USCAP, 94th Annual meeting

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開催年月日： 2005年2月

記述言語：英語会議種別：ポスター発表
TIA-1 Expression in Hairy Cell Leukemia 国際会議

United States and Canadian Academy of Pathology (USCAP), 93rd Annual Meeting

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開催年月日： 2004年3月

記述言語：英語会議種別：ポスター発表

講演・口頭発表等の先頭へ▲