Updated on 2023/10/13

写真a

 
TAKAHASHI, Yoshiyuki
 
Organization
Graduate School of Medicine Program in Integrated Medicine Medicine in Growth and Aging Professor
Graduate School
Graduate School of Medicine
Undergraduate School
School of Medicine Department of Medicine
Title
Professor

Degree 1

  1. Doctor of Medical Science ( 2000.3   Nagoya University School ofMedicine ) 

Research Interests 5

  1. Stem cell transplantation

  2. Immunology

  3. Oncology

  4. Hematology

  5. Pediatrics

Research Areas 3

  1. Others / Others  / Immunology

  2. Others / Others  / Hematology and Oncology

  3. Others / Others  / Pediatrics

Research History 11

  1. Nagoya University Graduate School of Medicine   Department of Pediatrics   Professor

    2016.10

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    Country:Japan

  2. Associate Professor, Departmen of Developmental Pediatrics, Nagoya University Graduate School of Medicine

    2011.10

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    Country:Japan

  3. Assintant Professor, Nagoya University Graduate School of Medicine

    2010.3 - 2011.9

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    Country:Japan

  4. Assintant Professor, Nagoya University Graduate School of Medicine

    2007.4 - 2010.2

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    Country:Japan

  5. Assistant Professor, Nagoya University Graduate Scholl of Medicine

    2006.4 - 2007.3

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    Country:Japan

  6. Medical Staff Fellow, Department of Pediatrics, NagoyaUniversity Graduate School of Medicine

    2006.1 - 2006.3

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    Country:Japan

  7. Medical Staff Fellow, Department of Pediatrics, Nagoya University School of Medicine

    2000.10 - 2001.3

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    Country:Japan

  8. Medical Staff Fellow, Meijo Hospital

    2000.4 - 2000.9

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    Country:Japan

  9. Medical Staff Fellow, Department of Pediatrics, Nagoya University School of Medicine

    1995.4 - 1996.3

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    Country:Japan

  10. Medical Staff Fellow, Children's Medical Center, Japanese Red Cross Hospital

    1994.4 - 1995.3

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    Country:Japan

  11. Internship, Japanese Red Cross Nagoya First Hospital

    1992.5 - 1994.3

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    Country:Japan

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Education 2

  1. Nagoya University Graduate School of Medicine   Department of Pediatrics   Hematology and Oncology

    1996.4 - 2000.3

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    Country: Japan

  2. Nagoya University   School of Medicine   School of Medicine

    1986.4 - 1992.3

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    Country: Japan

Professional Memberships 7

  1. The Japan Society for Hematopoietic Cell Transplantation   board member

    2016.4

  2. The Japanese Society of Pediatric Hematology/Oncology

  3. The Japanese Society of Hematology

  4. Japanese Pediatrics Society

  5. Japanese Cancer Association

  6. Society of Immunotherapy for Hematological Disorders

  7. American Society of Hematology

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Committee Memberships 4

  1. Stem cell transplantaion comittee, Japan Pediatric Lukemia/Lymphoma Study Group   Stem cell transplantation comittee  

    2010.10   

  2. Solid Tumor Working Group, The Japan Society for Hematopoietic Cell   Solid tumor Working Group  

    2010.10   

  3. HLA Working Group, The Japan Society for Hematopoietic Cell   HLA Working Group  

    2010.10   

  4. Pediatric ALL Working Group, The Japan Society for Hematopoietic Cell   Solid tumor Working Group  

    2010.10   

 

Papers 263

  1. Successful treatment of DOCK8 deficiency by allogeneic hematopoietic cell transplantation from alternative donors

    Kono Asuka, Wakamatsu Manabu, Umezawa Yoshihiro, Muramatsu Hideki, Fujiwara Hiroki, Tomomasa Dan, Inoue Kento, Hattori Keiichiro, Mitsui Tetsuo, Takada Hidetoshi, Minegishi Yoshiyuki, Takahashi Yoshiyuki, Yamamoto Masahide, Mori Takehiko, Kanegane Hirokazu

    INTERNATIONAL JOURNAL OF HEMATOLOGY   Vol. 118 ( 4 ) page: 519 - 525   2023.10

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s12185-023-03613-y

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  2. Early chemotherapeutic intervention to avoid thyroidectomy in pediatric Langerhans cell histiocytosis with thyroid involvement accompanying tracheal stenosis: a report of two cases.

    Aoyama S, Fukuoka K, Kubota H, Narita K, Kudo K, Mitani Y, Oshima K, Mori M, Arakawa Y, Ichimura K, Terui K, Tanami Y, Kawashima H, Nakazawa A, Niitsu T, Takahashi Y, Koh K

    International journal of hematology     2023.9

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    DOI: 10.1007/s12185-023-03662-3

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  3. Vedolizumab for children with intestinal graft-versus-host disease: a case report and literature review

    Fukuta Taro, Muramatsu Hideki, Yamashita Daiki, Sajiki Daichi, Maemura Ryo, Tsumura Yusuke, Yamamori Ayako, Imaya Masayuki, Wakamatsu Manabu, Nishikawa Eri, Narita Kotaro, Kataoka Shinsuke, Taniguchi Rieko, Narita Atsushi, Nishio Nobuhiro, Takahashi Yoshiyuki

    INTERNATIONAL JOURNAL OF HEMATOLOGY   Vol. 118 ( 3 ) page: 411 - 417   2023.9

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    DOI: 10.1007/s12185-023-03590-2

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  4. Development of TCR-T cell therapy targeting mismatched HLA-DPB1 for relapsed leukemia after allogeneic transplantation

    Barakat Carolyne, Inagaki Yuichiro, Mizuno Shohei, Nishio Nobuhiro, Katsuyama Naoya, Sato Yoshie, Kobayashi Miki, Ozeki Kazutaka, Iida Hiroatsu, Tomita Akihiro, Sawa Masashi, Demachi-Okamura Ayako, Takahashi Yoshiyuki, Nishikawa Hiroyoshi, Akatsuka Yoshiki

    INTERNATIONAL JOURNAL OF HEMATOLOGY   Vol. 118 ( 2 ) page: 252 - 266   2023.8

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    DOI: 10.1007/s12185-023-03621-y

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  5. Human leukocyte antigen 7/8-matched unrelated bone marrow transplantation using anti-thymocyte globulin in children

    Hamada Motoharu, Muramatsu Hideki, Torii Yuka, Suzuki Kyogo, Narita Atsushi, Yoshida Taro, Imaya Masayuki, Yamamori Ayako, Wakamatsu Manabu, Miwata Shunsuke, Narita Kotaro, Kataoka Shinsuke, Kawashima Nozomu, Taniguchi Rieko, Nishikawa Eri, Nishio Nobuhiro, Ito Yoshinori, Kojima Seiji, Takahashi Yoshiyuki

    INTERNATIONAL JOURNAL OF HEMATOLOGY   Vol. 118 ( 1 ) page: 125 - 130   2023.7

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    DOI: 10.1007/s12185-023-03571-5

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  6. Two Cases of Juvenile Myelomonocytic Leukemia and Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease

    Yamamoto Hiroyuki, Natsume Jun, Kaneko Kimihiko, Takahashi Toshiyuki, Wakamatsu Manabu, Ogawa Chikako, Kumai Sumire, Suzui Ryosuke, Sawamura Fumi, Shiraki Anna, Nakata Tomohiko, Kidokoro Hiroyuki, Muramatsu Hideki, Takahashi Yoshiyuki

    PEDIATRIC NEUROLOGY   Vol. 144   page: 1 - 4   2023.7

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    DOI: 10.1016/j.pediatrneurol.2023.03.002

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  7. Hematological abnormalities in Jacobsen syndrome: Cytopenia of varying severities and morphological abnormalities in peripheral blood and bone marrow.

    Yamashita D, Muramatsu H, Narita A, Wakamatsu M, Tsumura Y, Sajiki D, Maemura R, Yamamori A, Imaya M, Narita K, Kataoka S, Taniguchi R, Nishio N, Okuno Y, Fujita N, Koh K, Umeda K, Morihana E, Iwafuchi H, Ito M, Kojima S, Hama A, Takahashi Y

    Haematologica     2023.6

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    DOI: 10.3324/haematol.2022.282513

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  8. Successful living-donor liver transplantation for sustained liver failure even after resolution of infiltrative massive hepatic invasion of stage 4S neuroblastoma: a case report

    Jobara Kanta, Yamamori Ayako, Shizuku Masato, Kurata Nobuhiko, Fujimoto Yasuhiro, Muramatsu Hideki, Takahashi Yoshiyuki, Ogura Yasuhiro

    SURGICAL CASE REPORTS   Vol. 9 ( 1 ) page: 100   2023.6

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    DOI: 10.1186/s40792-023-01681-0

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  9. CLINICAL VALIDATION OF NOVEL URINARY MARKERS FOR NEUROBLASTOMA DIAGNOSIS

    Amano Hizuru, Uchida Hiroo, Harada Kazuharu, Narita Atsushi, Kumano Shun, Abe Mayumi, Sakairi Minoru, Shirota Chiyoe, Tainaka Takahisa, Sumida Wataru, Yokota Kazuki, Makita Satoshi, Osawa Tsuyoshi, Taguri Masataka, Takahashi Yoshiyuki, Hinoki Akinari

    PEDIATRIC BLOOD & CANCER   Vol. 70   page: S95 - S95   2023.6

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  10. Efficacy and safety of bevacizumab, irinotecan, and temozolomide combination for relapsed or refractory pediatric central nervous system embryonal tumor: a single-institution study

    Shiba Yoshiki, Motomura Kazuya, Taniguchi Rieko, Kurimoto Michihiro, Mizutani Kosuke, Ohka Fumiharu, Aoki Kosuke, Ito Eiji, Nishikawa Tomohide, Yamaguchi Junya, Kibe Yuji, Shimizu Hiroki, Maeda Sachi, Nakashima Takuma, Suzuki Hiromichi, Muramatsu Hideki, Takahashi Yoshiyuki, Saito Ryuta

    JOURNAL OF NEUROSURGERY-PEDIATRICS   Vol. 31 ( 6 ) page: 624 - 632   2023.6

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    DOI: 10.3171/2023.1.PEDS22345

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  11. Droplet Digital PCR Development for Adenovirus Load Monitoring in Children after Hematopoietic Stem Cell Transplantation

    Haruta Kazunori, Takeuchi Suguru, Yamaguchi Makoto, Horiba Kazuhiro, Suzuki Takako, Torii Yuka, Narita Atsushi, Muramatsu Hideki, Takahashi Yoshiyuki, Ito Yoshinori, Kawada Jun-ichi

    JOURNAL OF MOLECULAR DIAGNOSTICS   Vol. 25 ( 6 ) page: 403 - 409   2023.6

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    DOI: 10.1016/j.jmoldx.2023.03.004

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  12. Clinical and molecular features of CBL-mutated juvenile myelomonocytic leukemia.

    Yoshida T, Muramatsu H, Wakamatsu M, Sajiki D, Murakami N, Kitazawa H, Okamoto Y, Taniguchi R, Kataoka S, Narita A, Hama A, Okuno Y, Takahashi Y

    Haematologica     2023.5

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    DOI: 10.3324/haematol.2022.282385

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  13. Germline and somatic <i>RUNX1</i> variants in a pediatric bone marrow failure cohort

    Yamamori Ayako, Hamada Motoharu, Muramatsu Hideki, Wakamatsu Manabu, Hama Asahito, Narita Atsushi, Tsumura Yusuke, Yoshida Taro, Doi Takehiko, Terada Kazuki, Higa Takeshi, Yamamoto Nobuyuki, Miura Hiroki, Shiota Mitsutaka, Watanabe Kenichiro, Yoshida Nao, Maemura Ryo, Imaya Masayuki, Miwata Shunsuke, Narita Kotaro, Kataoka Shinsuke, Taniguchi Rieko, Suzuki Kyogo, Kawashima Nozomu, Nishio Nobuhiro, Iwafuchi Hideto, Ito Masafumi, Kojima Seiji, Okuno Yusuke, Takahashi Yoshiyuki

    AMERICAN JOURNAL OF HEMATOLOGY   Vol. 98 ( 5 ) page: E102 - E105   2023.5

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    DOI: 10.1002/ajh.26874

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  14. Haematopoietic cell transplantation for children with acute megakaryoblastic leukaemia without Down syndrome

    Hama Asahito, Taga Takashi, Tomizawa Daisuke, Muramatsu Hideki, Hasegawa Daiichiro, Adachi Souichi, Yoshida Nao, Noguchi Maiko, Sato Maho, Okada Keiko, Koh Katsuyoshi, Mitsui Tetsuo, Takahashi Yoshiyuki, Miyamura Takako, Hashii Yoshiko, Kato Koji, Atsuta Yoshiko, Okamoto Yasuhiro

    BRITISH JOURNAL OF HAEMATOLOGY   Vol. 201 ( 4 ) page: 747 - 756   2023.5

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    DOI: 10.1111/bjh.18691

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  15. Graft-versus-host disease-free, relapse-free, second transplant-free survival in allogeneic hematopoietic cell transplantation for genetic disorders

    Kawaguchi Koji, Umeda Katsutsugu, Miyamoto Satoshi, Yoshida Nao, Yabe Hiromasa, Koike Takashi, Kajiwara Michiko, Kawaguchi Hiroshi, Takahashi Yoshiyuki, Ishimura Masataka, Sakaguchi Hirotoshi, Hama Asahito, Cho Yuko, Sato Maho, Kato Keisuke, Sato Atsushi, Kato Koji, Tabuchi Ken, Atsuta Yoshiko, Imai Kohsuke

    BONE MARROW TRANSPLANTATION   Vol. 58 ( 5 ) page: 600 - 602   2023.5

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    DOI: 10.1038/s41409-023-01937-1

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  16. Novel xeno-free and serum-free culturing condition to improve piggyBac transposon-based CD19 chimeric antigen receptor T-cell production and characteristics

    Sanyanusin Mulita, Tudsamran Suparat, Thaiwong Rattapoom, Tawinwung Supannikar, Nishio Nobuhiro, Takahashi Yoshiyuki, Hirankarn Nattiya, Suppipat Koramit

    CYTOTHERAPY   Vol. 25 ( 4 ) page: 397 - 406   2023.4

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    DOI: 10.1016/j.jcyt.2022.11.009

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  17. Safety and efficacy of post-haematopoietic cell transplantation maintenance therapy with blinatumomab for relapsed/refractory CD19-positive B-cell acute lymphoblastic leukaemia: protocol for a phase I-II, multicentre, non-blinded, non-controlled trial (JPLSG SCT-ALL-BLIN21)

    Sakaguchi Hirotoshi, Umeda Katsustugu, Kato Itaru, Sakaguchi Kimiyoshi, Hiramatsu Hidefumi, Ishida Hiroyuki, Yabe Hiromasa, Goto Hiroaki, Kawahara Yuta, Yamashita Yuka Iijima, Sanada Masashi, Deguchi Takao, Takahashi Yoshiyuki, Saito Akiko, Noma Hisashi, Horibe Keizo, Taga Takashi, Adachi Souichi

    BMJ OPEN   Vol. 13 ( 4 ) page: e070051   2023.4

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    DOI: 10.1136/bmjopen-2022-070051

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  18. Fetal growth restriction followed by early catch-up growth impairs pancreatic islet morphology in male rats

    Jabary Mahboba, Onoda Atsuto, Kitase Yuma, Ueda Kazuto, Mimatsu Haruka, Go Shoji, Miura Ryosuke, Tsuji Masahiro, Takahashi Yoshiyuki, Hayakawa Masahiro, Sato Yoshiaki

    SCIENTIFIC REPORTS   Vol. 13 ( 1 ) page: 2732   2023.2

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    DOI: 10.1038/s41598-023-28584-2

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  19. Ruxolitinib in Pediatric Patients with Treatment-<i>Naive</i> or Steroid-Refractory Acute Graft-Versus-Host Disease: Primary Findings from the Phase I/II REACH4 Study

    Locatelli Franco, Kang Hyoung Jin, Bruno Benedicte, Gandemer Virginie, Rialland Fanny, Faraci Maura, Takahashi Yoshiyuki, Koh Katsuyoshi, Bittencourt Henrique, Cleary Grace, Rosko Christine, Roussou Pantelia, St Pierre Annie, Prahallad Anirudh, Diaz-de-Heredia Cristina

    BLOOD   Vol. 140   page: 1376 - 1378   2022.11

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    DOI: 10.1187/blood-2022-155708

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  20. Impact of the Coronavirus Disease 2019 Pandemic on the Clinical Features of Pediatric Respiratory Syncytial Virus Infection in Japan

    Ozeki Shoko, Kawada Jun-Ichi, Yamashita Daiki, Yasufuku Chika, Akano Takuya, Kato Masahiro, Suzuki Konomi, Tano Chihiro, Matsumoto Kazuki, Mizutani Shu-Hei, Mori Ayumi, Nishio Nobuhiro, Kidokoro Hiroyuki, Yasui Yoshihiro, Takahashi Yoshiyuki, Sato Yoshiaki

    OPEN FORUM INFECTIOUS DISEASES   Vol. 9 ( 11 ) page: ofac562   2022.11

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    DOI: 10.1093/ofid/ofac562

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  21. CHIMERIC ANTIGEN RECEPTOR T-CELL THERAPY FOLLOWED BY UR-BMT IN TYROSINE KINASE INHIBITOR RESISTANT PEDIATRIC PH1-POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA

    Imaya Masayuki, Narita Atsushi, Nishio Nobuhiro, Wakamatsu Manabu, Taniguchi Rieko, Kataoka Shinsuke, Muramatsu Hideki, Ichikawa Daisuke, Maeda Naoko, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 69   2022.11

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  22. Impact of human leukocyte antigen mismatch on outcomes after unrelated bone marrow transplantation in paediatric patients: A retrospective analysis by the JSTCT HLA working group

    Kato Itaru, Sakaguchi Hirotoshi, Kato Shunichi, Sato Maho, Noguchi Maiko, Yoshida Nao, Koh Katsuyoshi, Koike Takashi, Yanagimachi Masakatsu, Kato Keisuke, Takahashi Yoshiyuki, Fujita Naoto, Sato Atsushi, Hashii Yoshiko, Tabuchi Ken, Atsuta Yoshiko, Morishima Satoko, Kanda Junya

    BRITISH JOURNAL OF HAEMATOLOGY   Vol. 199 ( 3 ) page: 392 - 400   2022.11

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    DOI: 10.1111/bjh.18425

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  23. LI-FRAUMENI SYNDROME DIAGNOSED BY ONCOGENE PANEL TESTING FOR RHABDOMYOSARCOMA

    Taniguchi Rieko, Narita Atsushi, Muramatsu Hideki, Yamashita Daiki, Sajiki Daichi, Imaya Masayuki, Wakamatsu Manabu, Narita Kotaro, Nishio Nobuhiro, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 69   2022.11

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  24. INFANT WITH NEUROBLASTOMA STAGE 4S REQUIRING LIVING DONOR LIVER TRANSPLANTATION

    Yamamori Ayako, Muramatsu Hideki, Wakamatsu Manabu, Kataoka Shinsuke, Tsuyuki Yuta, Nishio Nobuhiro, Shimoyama Yoshie, Karube Kennosuke, Ogura Yasuhiro, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 69   2022.11

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  25. DANAZOL ADDED TO IMMUNOSUPPRESSIVE THERAPY IN CHILDREN WITH APLASTIC ANEMIA: A PROPENSITY SCORE-MATCHED COHORT STUDY

    Narita Atsushi, Kudo Kazuko, Muramatsu Hideki, Yagasaki Hiroshi, Kobayashi Ryoji, Yabe Hiromasa, Ohara Akira, Ohga Shouichi, Kojima Seiji, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 69   2022.11

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  26. HEMATOLOGICAL ABNORMALITIES IN JACOBSEN SYNDROME: PATIENTS NOT ONLY DEVELOP THROMBOCYTOPENIA, BUT ALSO ANEMIA AND NEUTROPENIA

    Yamashita Daiki, Muramatsu Hideki, Narita Atsushi, Fujita Naoto, Koh Katsuyoshi, Umeda Katsutsugu, Morihana Eiji, Hama Asahito, Ito Masafumi, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 69   2022.11

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  27. TREC/KREC Newborn Screening followed by Next-Generation Sequencing for Severe Combined Immunodeficiency in Japan

    Wakamatsu Manabu, Kojima Daiei, Muramatsu Hideki, Okuno Yusuke, Kataoka Shinsuke, Nakamura Fumiko, Sakai Yoshimi, Tsuge Ikuya, Ito Tsuyoshi, Ueda Kazuto, Saito Akiko, Morihana Eiji, Ito Yasuhiko, Ohashi Naoki, Tanaka Makito, Tanaka Taihei, Kojima Seiji, Nakajima Yoko, Ito Tetsuya, Takahashi Yoshiyuki

    JOURNAL OF CLINICAL IMMUNOLOGY   Vol. 42 ( 8 ) page: 1696 - 1707   2022.11

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    DOI: 10.1007/s10875-022-01335-0

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  28. RETROSPECTIVE NATIONWIDE SURVEY OF NONTUBERCULOUS MYCOBACTERIAL INFECTIONS IN PEDIATRIC HEMATOLOGY/ONCOLOGY PATIENTS

    Tsumura Yusuke, Muramatsu Hideki, Nishikawa Eri, Tetsuka Nobuyuki, Narita Atsushi, Inoue Kento, Cho Yuko, Motomura Yoshitomo, Hoshino Yoshihiko, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 69   2022.11

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  29. TREATMENT-RELATED TOXICITY OF ANTI-GD2 ANTIBODY IMMUNOTHERAPY AFTER ALLOGENEIC STEM CELL TRANSPLANTATION IN HIGH-RISK NEUROBLASTOMA PATIENTS

    Kataoka Shinsuke, Yamamori Ayako, Imaya Masayuki, Wakamatsu Manabu, Narita Kotaro, Taniguchi Rieko, Narita Atsushi, Muramatsu Hideki, Nishio Nobuhiro, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 69   2022.11

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  30. THREE CASES OF ABNORMAL TREC VALUES WITH COPY NUMBER ALTERATIONS IDENTIFIED IN SCID NEWBORN SCREENING PROGRAM

    Wakamatsu Manabu, Muramatsu Hideki, Kojima Daiei, Okuno Yusuke, Kataoka Shinsuke, Nakamura Tomiko, Sakai Yoshimi, Nakajima Yoko, Ito Tetsuya, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 69   2022.11

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  31. THE DISAPPEARANCE OF MINIMAL RESIDUAL DISEASE IN BONE MARROW DEMONSTRATES GRAFT VERSUS NEUROBLASTOMA EFFECT AFTER KIR-LIGAND MISMATCHED ALLOGENEIC CBT

    Alahmadi Rowaida, Nishio Nobuhiro, Wakamatsu Manabu, Kataoka Shinsuke, Narita Kotaro, Taniguchi Rieko, Narita Atsushi, Muramatsu Hideki, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 69   2022.11

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  32. RISK FACTORS FOR BLOOD STREAM INFECTIONS AFTER ALLOGENEIC HEMATOPOIETIC CELL TRANSPLANTATION IN CHILDREN

    Sajiki Daichi, Muramatsu Hideki, Wakamatsu Manabu, Narita Kotaro, Kataoka Shinsuke, Taniguchi Rieko, Narita Atsushi, Nishio Nobuhiro, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 69   2022.11

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  33. 5p deletion with congenital diaphragmatic hernia: a case report

    Kotani Tomomi, Ushida Takafumi, Nakamura Noriyuki, Imai Kenji, Iitani Yukako, Tano Sho, Iwagaki Shigenori, Takahashi Yuichiro, Ito Miharu, Hayakawa Masahiro, Kajiyama Hiroaki

    JOURNAL OF MEDICAL CASE REPORTS   Vol. 16 ( 1 ) page: 390   2022.10

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    DOI: 10.1186/s13256-022-03579-1

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  34. Involvement of the Thalamus, Hippocampus, and Brainstem in Hypsarrhythmia of West Syndrome: Simultaneous Recordings of Electroencephalography and fMRI Study

    Maki Y., Natsume J., Ito Y., Okai Y., Bagarinao E., Yamamoto H., Ogaya S., Takeuchi T., Fukasawa T., Sawamura F., Mitsumatsu T., Maesawa S., Saito R., Takahashi Y., Kidokoro H.

    AMERICAN JOURNAL OF NEURORADIOLOGY   Vol. 43 ( 10 ) page: 1502 - 1507   2022.10

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    DOI: 10.3174/ajnr.A7646

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  35. Quantitative assessment of viral load in the blood and urine of patients with congenital cytomegalovirus infection using droplet digital PCR

    Yamaguchi Makoto, Kawada Jun-ichi, Torii Yuka, Haruta Kazunori, Suzuki Takako, Horiba Kazuhiro, Takahashi Yoshiyuki, Ito Yoshinori

    JOURNAL OF MEDICAL VIROLOGY   Vol. 94 ( 9 ) page: 4559 - 4564   2022.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/jmv.27844

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  36. Clinical parameter-based prediction of DNA methylation classification generates a prediction model of prognosis in patients with juvenile myelomonocytic leukemia

    Imaizumi Takahiro, Meyer Julia, Wakamatsu Manabu, Kitazawa Hironobu, Murakami Norihiro, Okuno Yusuke, Yoshida Taro, Sajiki Daichi, Hama Asahito, Kojima Seiji, Takahashi Yoshiyuki, Loh Mignon, Stieglitz Elliot, Muramatsu Hideki

    SCIENTIFIC REPORTS   Vol. 12 ( 1 ) page: 14753   2022.8

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    DOI: 10.1038/s41598-022-18733-4

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  37. Whole-exome analysis of 177 pediatric patients with undiagnosed diseases

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    SCIENTIFIC REPORTS   Vol. 12 ( 1 ) page: 14589   2022.8

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    DOI: 10.1038/s41598-022-14161-6

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  38. Microsatellite instability-high is rare events in refractory pediatric solid tumors

    Yoshida Taro, Muramatsu Hideki, Wakamatsu Manabu, Taniguchi Rieko, Ichikawa Daisuke, Nakaguro Masato, Natsume Atsushi, Takahashi Yoshiyuki

    PEDIATRIC HEMATOLOGY AND ONCOLOGY   Vol. 39 ( 5 ) page: 468 - 474   2022.8

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    DOI: 10.1080/08880018.2021.1998266

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  39. Prognostic factors of children and adolescents with T-cell acute lymphoblastic leukemia after allogeneic transplantation

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    HEMATOLOGICAL ONCOLOGY   Vol. 40 ( 3 ) page: 457 - 468   2022.8

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    DOI: 10.1002/hon.2980

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  40. Risk factors for unplanned removal of central venous catheters in hospitalized children with hematological and oncological disorders

    Miyagishima Moe, Hamada Motoharu, Hirayama Yuji, Muramatsu Hideki, Tainaka Takahisa, Shirota Chiyoe, Hinoki Akinari, Imaizumi Takahiro, Nakatochi Masahiro, Kamei Michi, Nishikawa Eri, Kawashima Nozomu, Narita Atsushi, Nishio Nobuhiro, Kojima Seiji, Takahashi Yoshiyuki

    INTERNATIONAL JOURNAL OF HEMATOLOGY   Vol. 116 ( 2 ) page: 288 - 294   2022.8

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    DOI: 10.1007/s12185-022-03346-4

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  41. A patient with very early onset FH-deficient renal cell carcinoma diagnosed at age seven

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    FAMILIAL CANCER   Vol. 21 ( 3 ) page: 337 - 341   2022.7

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    DOI: 10.1007/s10689-021-00268-8

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  42. Difficulties in diagnosing Malassezia furfur bloodstream infection and possibility of spontaneous resolution in a patient undergoing chemotherapy for neuroblastoma: A case report

    Tetsuka Nobuyuki, Muramatsu Hideki, Iguchi Mitsutaka, Oka Keisuke, Morioka Hiroshi, Takahashi Yoshiyuki, Yagi Tetsuya

    JOURNAL OF INFECTION AND CHEMOTHERAPY   Vol. 28 ( 7 ) page: 987 - 990   2022.7

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    DOI: 10.1016/j.jiac.2022.02.026

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  43. Prognostic Factors for Outcomes of Allogeneic HSCT for Children and Adolescents/Young Adults With CML in the TKI Era

    Shimada Hiroyuki, Tanizawa Akihiko, Kondo Takeshi, Nagamura-Inoue Tokiko, Yasui Masahiro, Tojo Arinobu, Muramatsu Hideki, Eto Tetsuya, Doki Noriko, Tanaka Masatsugu, Sato Maho, Noguchi Maiko, Uchida Naoyuki, Takahashi Yoshiyuki, Sakata Naoki, Ichinohe Tatsuo, Hashii Yoshiko, Kato Koji, Atsuta Yoshiko, Ohashi Kazuteru

    TRANSPLANTATION AND CELLULAR THERAPY   Vol. 28 ( 7 ) page: 376 - 389   2022.7

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    DOI: 10.1016/j.jtct.2022.04.011

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  44. Registry data analysis of hematopoietic stem cell transplantation on systemic chronic active Epstein-Barr virus infection patients in Japan

    Yamamoto Masahide, Sato Maho, Onishi Yasushi, Sasahara Yoji, Sano Hideki, Masuko Masayoshi, Nakamae Hirohisa, Matsuoka Ken-ichi, Ara Takahide, Washio Kana, Onizuka Makoto, Watanabe Kenichiro, Takahashi Yoshiyuki, Hirakawa Tsuneaki, Nishio Miwako, Sakashita Chizuko, Kobayashi Tohru, Sawada Akihisa, Ichinohe Tatsuo, Fukuda Takahiro, Hashii Yoshiko, Atsuta Yoshiko, Arai Ayako

    AMERICAN JOURNAL OF HEMATOLOGY   Vol. 97 ( 6 ) page: 780 - 790   2022.6

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    DOI: 10.1002/ajh.26544

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  45. METABOLOMICS OF URINARY METABOLITES IN CHILDHOOD RHABDOMYOSARCOMA TO DISCOVER NOVEL BIOMARKERS

    Nakano Satoshi, Uchida Hiroo, Amano Hizuru, Narita Atsushi, Abe Mayumi, Ishigaki Takashi, Sakairi Minoru, Shirota Chiyoe, Sumida Wataru, Makita Satoshi, Takimoto Aitaro, Okamoto Masamune, Yasui Akihiro, Takada Shunya, Nakagawa Yoichi, Terui Yasushi, Sunagawa Masaki, Takahashi Yoshiyuki, Osawa Tsuyoshi, Hinoki Akinari

    PEDIATRIC BLOOD & CANCER   Vol. 69   2022.6

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  46. Combination chemotherapy consisting of irinotecan, etoposide, and carboplatin for refractory or relapsed neuroblastoma

    Imaya Masayuki, Muramatsu Hideki, Narita Atsushi, Yamamori Ayako, Wakamatsu Manabu, Yoshida Taro, Miwata Shunsuke, Narita Kotaro, Ichikawa Daisuke, Hamada Motoharu, Nishikawa Eri, Kawashima Nozomu, Nishio Nobuhiro, Kojima Seiji, Takahashi Yoshiyuki

    CANCER MEDICINE   Vol. 11 ( 9 ) page: 1956 - 1964   2022.5

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    DOI: 10.1002/cam4.4529

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  47. Predictive factors of acute respiratory events during initial induction chemotherapy in patients with advanced neuroblastoma

    Matsui Motohiro, Makimoto Atsushi, Nishio Nobuhiro, Takahashi Yoshiyuki, Urashima Mitsuyoshi, Yuza Yuki

    CANCER REPORTS   Vol. 5 ( 5 ) page: e1499   2022.5

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    DOI: 10.1002/cnr2.1499

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  48. Minor PNH clones do not distinguish inherited bone marrow failure syndromes from immune-mediated aplastic anemia

    Narita Atsushi, Miwata Shunsuke, Imaya Masayuki, Tsumura Yusuke, Yamamori Ayako, Wakamatsu Manabu, Hamada Motoharu, Taniguchi Rieko, Okuno Yusuke, Muramatsu Hideki, Takahashi Yoshiyuki

    BLOOD ADVANCES   Vol. 6 ( 8 ) page: 2517 - 2519   2022.4

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    DOI: 10.1182/bloodadvances.2021006044

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  49. Death review of children receiving medical care at home

    Natsume Jun, Numaguchi Atsushi, Ohno Atsuko, Mizuno Mihoko, Takahashi Yoshiyuki, Okumura Akihisa, Yoshikawa Tetsushi, Saitoh Shinji, Miura Kiyokuni, Noda Masaharu

    PEDIATRIC RESEARCH   Vol. 91 ( 5 ) page: 1286 - 1289   2022.4

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    DOI: 10.1038/s41390-021-01606-3

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  50. Hematopoietic Cell Transplantation for Inborn Errors of Immunity Other than Severe Combined Immunodeficiency in Japan: Retrospective Analysis for 1985-2016

    Miyamoto Satoshi, Umeda Katsutsugu, Kurata Mio, Yanagimachi Masakatsu, Iguchi Akihiro, Sasahara Yoji, Okada Keiko, Koike Takashi, Tanoshima Reo, Ishimura Masataka, Yamada Masafumi, Sato Maho, Takahashi Yoshiyuki, Kajiwara Michiko, Kawaguchi Hiroshi, Inoue Masami, Hashii Yoshiko, Yabe Hiromasa, Kato Koji, Atsuta Yoshiko, Imai Kohsuke, Morio Tomohiro

    JOURNAL OF CLINICAL IMMUNOLOGY   Vol. 42 ( 3 ) page: 529 - 545   2022.4

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    DOI: 10.1007/s10875-021-01199-w

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  51. Genetic Study of Fanconi Anemia in Infancy Revealed <i>FANCI</i> Mutations and Defective <i>ALDH2</i> Variant: A Case Report

    Urata Takayo, Imamura Toshihiko, Osone Shinya, Muramatsu Hideki, Takahashi Yoshiyuki, Hosoi Hajime

    JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY   Vol. 44 ( 2 ) page: E438 - E441   2022.3

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    DOI: 10.1097/MPH.0000000000002254

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  52. Short Report Nosocomial infection with rotavirus vaccine strain in paediatric patients with immunodeficiency

    Miura H., Taniguchi K., Narita K., Kawamura Y., Kozawa K., Muramatsu H., Takahashi Y., Ihira M., Yoshikawa T.

    JOURNAL OF HOSPITAL INFECTION   Vol. 121   page: 9 - 13   2022.3

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    DOI: 10.1016/j.jhin.2021.12.009

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  53. Prospective validation of the provisional entity of refractory cytopenia of childhood, proposed by the World Health Organization

    Hama Asahito, Hasegawa Daisuke, Manabe Atsushi, Nozawa Kazue, Narita Atsushi, Muramatsu Hideki, Kosaka Yoshiyuki, Kobayashi Masao, Koh Katsuyoshi, Takahashi Yoshiyuki, Watanabe Kenichiro, Ohara Akira, Ito Masafumi, Kojima Seiji

    BRITISH JOURNAL OF HAEMATOLOGY   Vol. 196 ( 4 ) page: 1031 - 1039   2022.2

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    DOI: 10.1111/bjh.17921

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  54. Targeting MEF2D-fusion Oncogenic Transcriptional Circuitries in B-cell Precursor Acute Lymphoblastic Leukemia

    Tsuzuki Shinobu, Yasuda Takahiko, Kawazu Masahito, Ueno Toshihide, Karnan Sivasundaram, Ota Akinobu, Sanada Masashi, Nagai Hirokazu, Tomita Akihiro, Takahashi Yoshiyuki, Miyazaki Yasushi, Matsumura Itaru, Kiyoi Hitoshi, Hosokawa Yoshitaka, Mano Hiroyuki, Hayakawa Fumihiko

    CANCER SCIENCE   Vol. 113   page: 1236 - 1236   2022.2

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  55. Dyserythropoietic anaemia with an intronic GATA1 splicing mutation in patients suspected to have Diamond-Blackfan anaemia.

    Kobayashi A, Ohtaka R, Toki T, Hara J, Muramatsu H, Kanezaki R, Takahashi Y, Sato T, Kamio T, Kudo K, Sasaki S, Yoshida T, Utsugisawa T, Kanno H, Yoshida K, Nannya Y, Takahashi Y, Kojima S, Miyano S, Ogawa S, Terui K, Ito E

    EJHaem   Vol. 3 ( 1 ) page: 163 - 167   2022.2

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    DOI: 10.1002/jha2.374

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  56. New mimic of relapse or regional lymph node metastasis in a cancer survivor: a case of mRNA COVID-19 vaccine-induced lymphadenitis with high FDG uptake

    Tsumura Yusuke, Asakura Koiku, Takahashi Ikuko, Akaihata Mitsuko, Takahashi Yoshiyuki, Ishida Yuji

    IMMUNOLOGICAL MEDICINE   Vol. 45 ( 1 ) page: 45 - 47   2022.1

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    DOI: 10.1080/25785826.2021.1999786

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  57. Dorsal myelopathy after nelarabine and intrathecal methotrexate therapy

    Sawamura Fumi, Natsume Jun, Nakata Tomohiko, Muramatsu Hideki, Takahashi Yoshiyuki

    PEDIATRICS INTERNATIONAL   Vol. 64 ( 1 ) page: e15334   2022.1

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    DOI: 10.1111/ped.15334

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  58. Conception by assisted reproductive technology in infants with critical congenital heart disease in Japan.

    Morimoto Y, Go K, Yamamoto H, Fukasawa Y, Nakai M, Morihana E, Yasuda K, Nishikawa H, Ohashi N, Takahashi Y, Kato T

    Reproductive biomedicine online   Vol. 44 ( 1 ) page: 163 - 170   2022.1

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    DOI: 10.1016/j.rbmo.2021.10.005

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  59. Clinical Impact of Melphalan Pharmacokinetics on Transplantation Outcomes in Children Undergoing Hematopoietic Stem Cell Transplantation

    Maemura Ryo, Wakamatsu Manabu, Matsumoto Kana, Sakaguchi Hirotoshi, Yoshida Nao, Hama Asahito, Yoshida Taro, Miwata Shunsuke, Kitazawa Hironobu, Narita Kotaro, Kataoka Shinsuke, Ichikawa Daisuke, Hamada Motoharu, Taniguchi Rieko, Suzuki Kyogo, Kawashima Nozomu, Nishikawa Eri, Narita Atsushi, Okuno Yusuke, Nishio Nobuhiro, Kato Koji, Kojima Seiji, Morita Kunihiko, Muramatsu Hideki, Takahashi Yoshiyuki

    CELL TRANSPLANTATION   Vol. 31   page: 9636897221143364   2022

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    DOI: 10.1177/09636897221143364

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  60. Simple and robust methylation test for risk stratification of patients with juvenile myelomonocytic leukemia

    Kitazawa Hironobu, Okuno Yusuke, Muramatsu Hideki, Aoki Kosuke, Murakami Norihiro, Wakamatsu Manabu, Suzuki Kyogo, Narita Kotaro, Kataoka Shinsuke, Ichikawa Daisuke, Hamada Motoharu, Taniguchi Rieko, Kawashima Nozomu, Nishikawa Eri, Narita Atsushi, Nishio Nobuhiro, Hama Asahito, Loh Mignon L., Stieglitz Elliot, Kojima Seiji, Takahashi Yoshiyuki

    BLOOD ADVANCES   Vol. 5 ( 24 ) page: 5507 - 5518   2021.12

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    DOI: 10.1182/bloodadvances.2021005080

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  61. Altered effect of killer immunoglobulin-like receptor-ligand mismatch by graft versus host disease prophylaxis in cord blood transplantation

    Yokoyama Hisayuki, Hirayama Masahiro, Takahashi Yoshiyuki, Uchida Naoyuki, Tanaka Masatsugu, Onizuka Makoto, Ozawa Yukiyasu, Onai Daishi, Katsuoka Yuna, Wake Atsushi, Sawa Masashi, Kobayashi Hikaru, Maruyama Yumiko, Ozeki Kazutaka, Kimura Takafumi, Kanda Junya, Fukuda Takahiro, Atsuta Yoshiko, Terakura Seitaro, Morishima Satoko

    BONE MARROW TRANSPLANTATION   Vol. 56 ( 12 ) page: 3059 - 3067   2021.12

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    DOI: 10.1038/s41409-021-01469-6

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  62. Effectiveness of lacosamide in children and young adults previously treated with other sodium channel blockers

    Suzuki Takeshi, Natsume Jun, Kumai Sumire, Maki Yuki, Yamamoto Hiroyuki, Numoto Shingo, Narahara Sho, Kubota Tetsuo, Tsuji Takeshi, Kato Toru, Yamada Keitaro, Maruyama Koichi, Okumura Akihisa, Takahashi Yoshiyuki, Kidokoro Hiroyuki

    EPILEPSY & BEHAVIOR   Vol. 125   page: 108397   2021.12

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    DOI: 10.1016/j.yebeh.2021.108397

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  63. Prognostic value of the revised International Prognostic Scoring System five-group cytogenetic abnormality classification for the outcome prediction of hematopoietic stem cell transplantation in pediatric myelodysplastic syndrome

    Yamamoto Shohei, Kato Motohiro, Watanabe Kenichiro, Ishimaru Sae, Hasegawa Daisuke, Noguchi Maiko, Hama Asahito, Sato Maho, Koike Takashi, Iwasaki Fuminori, Yagasaki Hiroshi, Takahashi Yoshiyuki, Kosaka Yoshiyuki, Hashii Yoshiko, Morimoto Akira, Atsuta Yoshiko, Hasegawa Daiichiro, Yoshida Nao

    BONE MARROW TRANSPLANTATION   Vol. 56 ( 12 ) page: 3016 - 3023   2021.12

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    DOI: 10.1038/s41409-021-01446-z

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  64. A Phase I Study of CD19 Chimeric Antigen Receptor-T Cells Generated By the PiggyBac Transposon Vector for Acute Lymphoblastic Leukemia

    Nishio Nobuhiro, Hanajiri Ryo, Ishikawa Yuichi, Murata Makoto, Taniguchi Rieko, Hamada Motoharu, Nishikawa Eri, Kawashima Nozomu, Narita Atsushi, Muramatsu Hideki, Takahashi Yoshiyuki

    BLOOD   Vol. 138   page: 3831 - +   2021.11

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    DOI: 10.1182/blood-2021-150469

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  65. Clinical Features of Immature Leukemias in Children

    Sajiki Daichi, Yoshida Nao, Muramatsu Hideki, Sakaguchi Kimiyoshi, Maeda Naoko, Yokoyama Norifumi, Miyajima Yuji, Tanaka Makito, Takahashi Yoshiyuki, Hama Asahito

    PEDIATRIC BLOOD & CANCER   Vol. 68   2021.11

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  66. A Case of FOXN1-SCID Identified by TREC/KREC Newborn Screening Program

    Wakamatsu Manabu, Kojima Daiei, Muramatsu Hideki, Okuno Yusuke, Kataoka Shinsuke, Nakamura Tomiko, Sakai Yoshimi, Nakajima Yoko, Ito Tetsuya, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 68   2021.11

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  67. A Case of Severe Combined Immunodeficiency found in Newborn Screening for Primary Immunodeficiency in Aichi Prefecture

    Yamashita Daiki, Wakamatsu Manabu, Muramatsu Hideki, Kojima Daiei, Kataoka Shinsuke, Okuno Yusuke, Nakamura Fumiko, Sakai Yoshimi, Ito Tetsuya, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 68   2021.11

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  68. Cartilage-Hair Hypoplasia Diagnosed after Optional Screening of Neonates for Severe Combined Immunodeficiency

    Tsumura Yusuke, Wakamatsu Manabu, Muramatsu Hideki, Okuno Yusuke, Nakajima Yoko, Ito Tetsuya, Nakamura Tomiko, Sakai Yoshimi, Kojima Seji, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 68   2021.11

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  69. Clinical Characteristics and Outcomes of Acute Megakaryoblastic Leukemia with T(1;22)(P13;Q13) in Children

    Hama Asahito, Nagai Kozo, Hasegawa Daisuke, Hasegawa Daichiro, Shimada Akira, Takahashi Yoshiyuki, Taga Takashi, Adachi Souichi, Tomizawa Daisuke

    PEDIATRIC BLOOD & CANCER   Vol. 68   2021.11

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  70. A Case of Fanct without Abnormality in the Peripheral Blood Chromosome Breakage Test

    Nishi Masanori, Eguchi Hiroi, Muramatsu Hideki, Takahashi Yoshiyuki, Matsuo Muneaki

    PEDIATRIC BLOOD & CANCER   Vol. 68   2021.11

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  71. Hematopoietic Cell Transplantation for Severe Combined Immunodeficiency Patients: a Japanese Retrospective Study

    Miyamoto Satoshi, Umeda Katsutsugu, Kurata Mio, Nishimura Akira, Yanagimachi Masakatsu, Ishimura Masataka, Sato Maho, Shigemura Tomonari, Kato Motohiro, Sasahara Yoji, Iguchi Akihiro, Koike Takashi, Takahashi Yoshiyuki, Kajiwara Michiko, Inoue Masami, Hashii Yoshiko, Yabe Hiromasa, Kato Koji, Atsuta Yoshiko, Imai Kohsuke, Morio Tomohiro

    JOURNAL OF CLINICAL IMMUNOLOGY   Vol. 41 ( 8 ) page: 1865 - 1877   2021.11

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    DOI: 10.1007/s10875-021-01112-5

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  72. Urinary Biomarkers Predicting Treatment Outcomes in Neuroblastoma

    Narita Atsushi, Hinoki Akinari, Yokota Kazuki, Hamada Motoharu, Kataoka Shinsuke, Kawashima Nozomu, Muramatsu Hideki, Nishio Nobuhiro, Uchida Hiroo, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 68   2021.11

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  73. Using Chemotherapy to Treat Neuroblastoma Stage 4S with Hepatomegaly in a Patient Younger than 2 Months Old

    Imaya Masayuki, Nishio Nobuhiro, Taniguchi Rieko, Kataoka Shinsuke, Hamada Motoharu, Nishikawa Eri, Kawashima Nozomu, Narita Atsushi, Muramatsu Hideki, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 68   2021.11

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  74. Next-Generation Sequencing to Detect Pathogens in Pediatric Febrile Neutropenia: A Single-Center Retrospective Study of 112 Cases

    Horiba Kazuhiro, Torii Yuka, Okumura Toshihiko, Takeuchi Suguru, Suzuki Takako, Kawada Jun-Ichi, Muramatsu Hideki, Takahashi Yoshiyuki, Ogi Tomoo, Ito Yoshinori

    OPEN FORUM INFECTIOUS DISEASES   Vol. 8 ( 11 ) page: ofab223   2021.11

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    DOI: 10.1093/ofid/ofab223

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  75. RE-Treatment with CD19-Targeted CAR-T Cells for Relapse after CD19-CAR-T Cell Therapy

    Nishio Nobuhiro, Hamada Motoharu, Nishikawa Eri, Kawashima Nozomu, Narita Atsushi, Muramatsu Hideki, Wang Kai, Zheng Huyong, Chang Jung-Li, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 68   2021.11

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  76. Prolonged Hospitalization and Late Gastroenterological Complications in Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

    Kawashima Nozomu, Kataoka Shinsuke, Hamada Motoharu, Nishikawa Eri, Taniguchi Rieko, Narita Atsushi, Muramatsu Hideki, Nishio Nobuhiro, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 68   2021.11

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  77. Outcomes of KIR-Ligand Incompatible Allogeneic Cord Blood Transplantation for Relapsed Stage 4 Neuroblastoma: A Single Institutional Study

    Kataoka Shinsuke, Nishio Nobuhiro, Wakamatsu Manabu, Taniguchi Rieko, Nishikawa Eri, Hamada Motoharu, Kawashima Nozomu, Narita Atsushi, Muramatsu Hideki, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 68   2021.11

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  78. Strategy of Intensified Therapy for High Risk Pediatric Acute Lymphoblastic Leukemia Based on NGS-MRD-Based Risk Stratification

    Hamada Motoharu, Imaya Masayuki, Okuno Yusuke, Kawashima Nozomu, Taniguchi Rieko, Narita Atsushi, Muramatsu Hideki, Nishio Nobuhiro, Hasegawa Shinji, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 68   2021.11

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  79. Ten Patients with RUNX1 Mutation who were Suspected with FPD-MM in a Pediatric Cohort of Inherited Bone Marrow Failure Syndrome

    Yamamori Ayako, Hamada Motoharu, Muramatsu Hideki, Taniguchi Rieko, Kataoka Shinsuke, Kawashima Nozomu, Narita Atsushi, Nishio Nobuhiro, Okuno Yusuke, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 68   2021.11

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  80. Successful Therapy with Ascites Drainage and Defibrotide for Veno-Occlusive Disease Developed after Bone Marrow Transplantation in Acute Lymphoblastic Leukemia

    Maemura Ryo, Narita Atsushi, Kataoka Shinsuke, Taniguchi Rieko, Hamada Motoharu, Nishikawa Eri, Kawashima Nozomu, Nishio Nobuhiro, Muramatsu Hideki, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 68   2021.11

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  81. Hematopoietic stem cell transplantation for infants with high-risk <i>KMT2A</i> gene-rearranged acute lymphoblastic leukemia

    Takachi Takayuki, Watanabe Tomoyuki, Miyamura Takako, Saito Akiko Moriya, Deguchi Takao, Hori Toshinori, Yamada Tomomi, Ohmori Shigeru, Haba Masami, Aoki Yuki, Ishimaru Sae, Sasaki Shinya, Ohshima Junjiro, Iguchi Akihiro, Takahashi Yoshiyuki, Hyakuna Nobuyuki, Manabe Atsushi, Horibe Keizo, Ishii Eiichi, Koh Katsuyoshi, Tomizawa Daisuke

    BLOOD ADVANCES   Vol. 5 ( 19 ) page: 3891 - 3899   2021.10

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    DOI: 10.1182/bloodadvances.2020004157

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  82. Single-Arm Non-Blinded Multicenter Clinical Trial on T-Cell-Replete Haploidentical Stem Cell Transplantation Using Low-Dose Antithymocyte Globulin for Relapsed and Refractory Pediatric Acute Leukemia.

    Kada A, Kikuta A, Saito AM, Kato K, Iguchi A, Yabe H, Ishida H, Hyakuna N, Takahashi Y, Nagasawa M, Hashii Y, Umeda K, Matsumoto K, Fujisaki H, Yano M, Nakazawa Y, Sano H

    The Kurume medical journal   Vol. 66 ( 3 ) page: 161 - 168   2021.10

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    DOI: 10.2739/kurumemedj.MS663004

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  83. Clinical Images: Extensive multiple organ involvement in VEXAS syndrome

    Takahashi Noriyuki, Takeichi Takuya, Nishida Tetsuya, Sato Juichi, Takahashi Yasuhiro, Yamamura Masahiro, Ogi Tomoo, Akiyama Masashi

    ARTHRITIS & RHEUMATOLOGY   Vol. 73 ( 10 ) page: 1896 - 1897   2021.10

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    DOI: 10.1002/art.41775

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  84. Acquisition of a rare <i>NUP98</i>-<i>BPTF</i> fusion gene associated with recurrence of acute myeloid leukemia

    Kawaguchi Koji, Azumi Shohei, Itakura Yosuke, Takachi Takayuki, Ogura Taemi, Horikoshi Yasuo, Suzuki Kyogo, Muramatsu Hideki, Hama Asahito, Takahashi Yoshiyuki, Watanabe Kenichiro

    PEDIATRIC BLOOD & CANCER   Vol. 68 ( 10 ) page: e29201   2021.10

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    DOI: 10.1002/pbc.29201

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  85. Usefulness of functional splicing analysis to confirm precise disease pathogenesis in Diamond-Blackfan anemia caused by intronic variants in <i>RPS19</i>

    Takafuji Satoru, Mori Takeshi, Nishimura Noriyuki, Yamamoto Nobuyuki, Uemura Suguru, Nozu Kandai, Terui Kiminori, Toki Tsutomu, Ito Etsuro, Muramatsu Hideki, Takahashi Yoshiyuki, Matsuo Masafumi, Yamamura Tomohiko, Iijima Kazumoto

    PEDIATRIC HEMATOLOGY AND ONCOLOGY   Vol. 38 ( 6 ) page: 515 - 527   2021.9

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    DOI: 10.1080/08880018.2021.1887984

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  86. Clinical diagnostic value of telomere length measurement in inherited bone marrow failure syndromes

    Miwata Shunsuke, Narita Atsushi, Okuno Yusuke, Suzuki Kyogo, Hamada Motoharu, Yoshida Taro, Imaya Masayuki, Yamamori Ayako, Wakamatsu Manabu, Narita Kotaro, Kitazawa Hironobu, Ichikawa Daisuke, Taniguchi Rieko, Kawashima Nozomu, Nishikawa Eri, Nishio Nobuhiro, Kojima Seiji, Muramatsu Hideki, Takahashi Yoshiyuki

    HAEMATOLOGICA   Vol. 106 ( 9 ) page: 2511 - 2515   2021.9

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    DOI: 10.3324/haematol.2021.278334

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  87. Autoantibodies against the plakin family proteins as a novel marker for chronic graft-versus-host disease of the lung

    Kawashima Nozomu, Nishikawa Eri, Tsuchisaka Atsunari, Hashimoto Takashi, Okuno Yusuke, Hamada Motoharu, Ichikawa Daisuke, Narita Atsushi, Muramatsu Hideki, Nishio Nobuhiro, Kojima Seiji, Muro Yoshinao, Takahashi Yoshiyuki

    BONE MARROW TRANSPLANTATION   Vol. 56 ( 9 ) page: 2291 - 2294   2021.9

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    DOI: 10.1038/s41409-021-01335-5

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  88. Echocardiography Monitoring of Pulmonary Hypertension after Pediatric Hematopoietic Stem Cell Transplantation: Pediatric Pulmonary Arterial Hypertension and Pulmonary Veno-Occlusive Disease after Hematopoietic Stem Cell Transplantation

    Kawashima Nozomu, Fukasawa Yoshie, Nishikawa Eri, Ohta-Ogo Keiko, Ishibashi-Ueda Hatsue, Hamada Motoharu, Ichikawa Daisuke, Narita Atsushi, Okuno Yusuke, Muramatsu Hideki, Nishio Nobuhiro, Kojima Seiji, Kato Taichi, Takahashi Yoshiyuki

    TRANSPLANTATION AND CELLULAR THERAPY   Vol. 27 ( 9 ) page: 786.e1 - 786.e8   2021.9

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    DOI: 10.1016/j.jtct.2021.05.017

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  89. Effect of high-dose chemotherapy plus stem cell rescue on the survival of patients with neuroblastoma modified by MYCN gene gain/amplification and remission status: a nationwide registration study in Japan

    Saito Yuya, Urashima Mitsuyoshi, Takahashi Yoshiyuki, Ogawa Atsushi, Kiyotani Chikako, Yuza Yuki, Koh Katsuyoshi, Watanabe Kenichiro, Kosaka Yoshiyuki, Goto Hiroaki, Kikuta Atsushi, Okada Keiko, Koga Yuhki, Fujimura Junya, Inoue Masami, Sato Atsushi, Atsuta Yoshiko, Matsumoto Kimikazu

    BONE MARROW TRANSPLANTATION   Vol. 56 ( 9 ) page: 2173 - 2182   2021.9

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    DOI: 10.1038/s41409-021-01303-z

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  90. Relationship between plasma rabbit anti-thymocyte globulin concentration and immunosuppressive therapy response in patients with severe aplastic anemia

    Narita Atsushi, Muramatsu Hideki, Ichikawa Daisuke, Hamada Motoharu, Nishikawa Eri, Suzuki Kyogo, Kawashima Nozomu, Okuno Yusuke, Nishio Nobuhiro, Hama Asahito, Yamazaki Hirohito, Nakao Shinji, Kojima Seiji, Takahashi Yoshiyuki

    EUROPEAN JOURNAL OF HAEMATOLOGY   Vol. 107 ( 2 ) page: 255 - 264   2021.8

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    DOI: 10.1111/ejh.13644

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  91. Successful treatment of a novel type I interferonopathy due to a de novo PSMB9 gene mutation with a Janus kinase inhibitor

    Kataoka Shinsuke, Kawashima Nozomu, Okuno Yusuke, Muramatsu Hideki, Miwata Shunsuke, Narita Kotaro, Hamada Motoharu, Murakami Norihiro, Taniguchi Rieko, Ichikawa Daisuke, Kitazawa Hironobu, Suzuki Kyogo, Nishikawa Eri, Narita Atsushi, Nishio Nobuhiro, Yamamoto Hidenori, Fukasawa Yoshie, Kato Taichi, Yamamoto Hiroyuki, Natsume Jun, Kojima Seiji, Nishino Ichizo, Taketani Takeshi, Ohnishi Hidenori, Takahashi Yoshiyuki

    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY   Vol. 148 ( 2 ) page: 639 - 644   2021.8

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    DOI: 10.1016/j.jaci.2021.03.010

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  92. Repetitive sleep starts: An important differential diagnosis of infantile spasms

    Maki Yuki, Kidokoro Hiroyuki, Okumura Akihisa, Yamamoto Hiroyuki, Nakata Tomohiko, Fukasawa Tatsuya, Kubota Tetsuo, Kawaguchi Masahiro, Suzuki Takeshi, Tanaka Masaharu, Okai Yu, Sakaguchi Yoko, Ohno Atsuko, Negoro Tamiko, Takahashi Yoshiyuki, Natsume Jun

    EPILEPSY & BEHAVIOR   Vol. 121 ( Pt A ) page: 108075   2021.8

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    DOI: 10.1016/j.yebeh.2021.108075

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  93. Intravenously delivered multilineage-differentiating stress enduring cells dampen excessive glutamate metabolism and microglial activation in experimental perinatal hypoxic ischemic encephalopathy

    Suzuki Toshihiko, Sato Yoshiaki, Kushida Yoshihiro, Tsuji Masahiro, Wakao Shohei, Ueda Kazuto, Imai Kenji, Iitani Yukako, Shimizu Shinobu, Hida Hideki, Temma Takashi, Saito Shigeyoshi, Iida Hidehiro, Mizuno Masaaki, Takahashi Yoshiyuki, Dezawa Mari, Borlongan Cesar V, Hayakawa Masahiro

    JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM   Vol. 41 ( 7 ) page: 1707 - 1720   2021.7

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    DOI: 10.1177/0271678X20972656

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  94. Integrated diagnosis based on transcriptome analysis in suspected pediatric sarcomas

    Ichikawa Daisuke, Yamashita Kyoko, Okuno Yusuke, Muramatsu Hideki, Murakami Norihiro, Suzuki Kyogo, Kojima Daiei, Kataoka Shinsuke, Hamada Motoharu, Taniguchi Rieko, Nishikawa Eri, Kawashima Nozomu, Narita Atsushi, Nishio Nobuhiro, Hama Asahito, Kasai Kenji, Mizuno Seiji, Shimoyama Yoshie, Nakaguro Masato, Okita Hajime, Kojima Seiji, Nakazawa Atsuko, Takahashi Yoshiyuki

    NPJ GENOMIC MEDICINE   Vol. 6 ( 1 ) page: 49   2021.6

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    DOI: 10.1038/s41525-021-00210-y

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  95. Age estimates from brain magnetic resonance images of children younger than two years of age using deep learning

    Kawaguchi Masahiro, Kidokoro Hiroyuki, Ito Rintaro, Shiraki Anna, Suzuki Takeshi, Maki Yuki, Tanaka Masaharu, Sakaguchi Yoko, Yamamoto Hiroyuki, Takahashi Yosiyuki, Naganawa Shinji, Natsume Jun

    MAGNETIC RESONANCE IMAGING   Vol. 79   page: 38 - 44   2021.6

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    DOI: 10.1016/j.mri.2021.03.004

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  96. A Phase 2 Open-label, Single-arm, Multicenter Study of Ruxolitinib Added to Corticosteroids in Pediatric Subjects with Moderate/Severe Chronic Gvhd After Allogeneic Stem Cell Transplantation (REACH5)

    Wall Donna, Koh Katsuyoshi, Bhat Sunil, Takahashi Yoshiyuki, Zhang Angela, Rosko Christine, Smith Yvonne, Stefanelli Tommaso, Diaz-de-Heredia Cristina, Locatelli Franco

    BONE MARROW TRANSPLANTATION   Vol. 56 ( SUPPL 1 ) page: 228 - 229   2021.6

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  97. Urinary biomarkers for monitoring treatment response in neuroblastoma patients.

    Amano Hizuru, Hinoki Akinari, Uchida Hiroo, Yokota Kazuki, Ishigaki Takashi, Sakairi Minoru, Abe Mayumi, Takahashi Yoshiyuki, Narita Atsushi, Tainaka Takahisa, Shirota Chiyoe, Sumida Wataru, Makita Satoshi, Takimoto Aitaro, Kano Yoko, Yasui Akihiro, Okamoto Masamune, Nakagawa Yoichi

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 39 ( 15 )   2021.5

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    DOI: 10.1200/JCO.2021.39.15_suppl.e22008

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  98. Whole genome sequencing of 45 Japanese patients with intellectual disability

    Abe-Hatano Chihiro, Iida Aritoshi, Kosugi Shunichi, Momozawa Yukihide, Terao Chikashi, Ishikawa Keiko, Okubo Mariko, Hachiya Yasuo, Nishida Hiroya, Nakamura Kazuyuki, Miyata Rie, Murakami Chie, Takahashi Kan, Hoshino Kyoko, Sakamoto Haruko, Ohta Sayaka, Kubota Masaya, Takeshita Eri, Ishiyama Akihiko, Nakagawa Eiji, Sasaki Masayuki, Kato Mitsuhiro, Matsumoto Naomichi, Kamatani Yoichiro, Kubo Michiaki, Takahashi Yoshiyuki, Natsume Jun, Inoue Ken, Goto Yu-Ichi

    AMERICAN JOURNAL OF MEDICAL GENETICS PART A   Vol. 185 ( 5 ) page: 1468 - 1480   2021.5

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    DOI: 10.1002/ajmg.a.62138

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  99. Reduced-intensity conditioning is effective for hematopoietic stem cell transplantation in young pediatric patients with Diamond-Blackfan anemia

    Koyamaishi Shun, Kamio Takuya, Kobayashi Akie, Sato Tomohiko, Kudo Ko, Sasaki Shinya, Kanezaki Rika, Hasegawa Daiichiro, Muramatsu Hideki, Takahashi Yoshiyuki, Sasahara Yoji, Hiramatsu Hidefumi, Kakuda Harumi, Tanaka Miyuki, Ishimura Masataka, Nishi Masanori, Ishiguro Akira, Yabe Hiromasa, Sarashina Takeo, Yamamoto Masaki, Yuza Yuki, Hyakuna Nobuyuki, Yoshida Kenichi, Kanno Hitoshi, Ohga Shouichi, Ohara Akira, Kojima Seiji, Miyano Satoru, Ogawa Seishi, Toki Tsutomu, Terui Kiminori, Ito Etsuro

    BONE MARROW TRANSPLANTATION   Vol. 56 ( 5 ) page: 1013 - 1020   2021.5

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    DOI: 10.1038/s41409-020-01056-1

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  100. Correction: Reduced-intensity conditioning is effective for hematopoietic stem cell transplantation in young pediatric patients with Diamond-Blackfan anemia.

    Koyamaishi S, Kamio T, Kobayashi A, Sato T, Kudo K, Sasaki S, Kanezaki R, Hasegawa D, Muramatsu H, Takahashi Y, Sasahara Y, Hiramatsu H, Kakuda H, Tanaka M, Ishimura M, Nishi M, Ishiguro A, Yabe H, Sarashina T, Yamamoto M, Yuza Y, Hyakuna N, Yoshida K, Kanno H, Ohga S, Ohara A, Kojima S, Miyano S, Ogawa S, Toki T, Terui K, Ito E

    Bone marrow transplantation   Vol. 56 ( 5 ) page: 1218 - 1219   2021.5

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    DOI: 10.1038/s41409-020-01076-x

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  101. Temporal dynamics of the plasma microbiome in recipients at early post-liver transplantation: a retrospective study

    Okumura Toshihiko, Horiba Kazuhiro, Kamei Hideya, Takeuchi Suguru, Suzuki Takako, Torii Yuka, Kawada Jun-ichi, Takahashi Yoshiyuki, Ogura Yasuhiro, Ogi Tomoo, Ito Yoshinori

    BMC MICROBIOLOGY   Vol. 21 ( 1 ) page: 104   2021.4

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    DOI: 10.1186/s12866-021-02154-w

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  102. Hippocampal Atrophy in Pediatric Transplant Recipients with Human Herpesvirus 6B

    Miyake Misa, Kawamura Yoshiki, Ishihara Naoko, Suzuki Shigetaka, Miura Hiroki, Sakaguchi Yoko, Tanaka Masaharu, Takahashi Yoshiyuki, Kojima Seiji, Toyama Hiroshi, Natsume Jun, Yoshikawa Tetsushi

    MICROORGANISMS   Vol. 9 ( 4 )   2021.4

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    DOI: 10.3390/microorganisms9040776

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  103. Phase I clinical trial of intra-bone marrow cotransplantation of mesenchymal stem cells in cord blood transplantation

    Goto Tatsunori, Murata Makoto, Nishida Tetsuya, Terakura Seitaro, Kamoshita Sonoko, Ishikawa Yuichi, Ushijima Yoko, Adachi Yoshiya, Suzuki Satoshi, Kato Katsuyoshi, Hirakawa Akihiro, Nishiwaki Satoshi, Nishio Nobuhiro, Takahashi Yoshiyuki, Kodera Yoshihisa, Matsushita Tadashi, Kiyoi Hitoshi

    STEM CELLS TRANSLATIONAL MEDICINE   Vol. 10 ( 4 ) page: 542 - 553   2021.4

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    DOI: 10.1002/sctm.20-0381

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  104. Phosphorylated proteome analysis of a novel germline <i>ABL1</i> mutation causing an autosomal dominant syndrome with ventricular septal defect

    Yamamoto Hidenori, Hayano Satoshi, Okuno Yusuke, Onoda Atsuto, Kato Kohji, Nagai Noriko, Fukasawa Yoshie, Saitoh Shinji, Takahashi Yoshiyuki, Kato Taichi

    INTERNATIONAL JOURNAL OF CARDIOLOGY   Vol. 326   page: 81 - 87   2021.3

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    DOI: 10.1016/j.ijcard.2020.10.032

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  105. Initial treatment of seizures in children in an emergency department in rural Japan

    Shiraki Anna, Yasui Masahiro, Kidokoro Hiroyuki, Kido Shinji, Ando Hideo, Takahashi Yoshiyuki, Natsume Jun

    BRAIN & DEVELOPMENT   Vol. 43 ( 2 ) page: 288 - 293   2021.2

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    DOI: 10.1016/j.braindev.2020.08.004

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  106. Combination of tumor necrosis factor-α and epidermal growth factor induces the adrenergic-to-mesenchymal transdifferentiation in SH-SY5Y neuroblastoma cells

    Huang Yue, Tsubota Shoma, Nishio Nobuhiro, Takahashi Yoshiyuki, Kadomatsu Kenji

    CANCER SCIENCE   Vol. 112 ( 2 ) page: 715 - 724   2021.2

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    DOI: 10.1111/cas.14760

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  107. Shuffling babies and autism spectrum disorder

    Okai Yu, Nakata Tomohiko, Miura Kiyokuni, Ohno Atsuko, Wakako Rie, Takahashi Osamu, Maki Yuki, Tanaka Masaharu, Sakaguchi Yoko, Ito Yuji, Yamamoto Hiroyuki, Kidokoro Hiroyuki, Takahashi Yoshiyuki, Natsume Jun

    BRAIN & DEVELOPMENT   Vol. 43 ( 2 ) page: 181 - 185   2021.2

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    DOI: 10.1016/j.braindev.2020.08.007

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  108. Long-term outcome in patients with Fanconi anemia who received hematopoietic stem cell transplantation: a retrospective nationwide analysis

    Yabe Miharu, Morio Tomohiro, Tabuchi Ken, Tomizawa Daisuke, Hasegawa Daiichiro, Ishida Hiroyuki, Yoshida Nao, Koike Takashi, Takahashi Yoshiyuki, Koh Katsuyoshi, Okamoto Yasuhiro, Sano Hideki, Kato Keisuke, Kanda Yoshinobu, Goto Hiroaki, Takita Junko, Miyamura Takako, Noguchi Maiko, Kato Koji, Hashii Yoshiko, Astuta Yoshiko, Yabe Hiromasa

    INTERNATIONAL JOURNAL OF HEMATOLOGY   Vol. 113 ( 1 ) page: 134 - 144   2021.1

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    DOI: 10.1007/s12185-020-02991-x

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  109. Detection of subclonal <i>SETBP1</i> and <i>JAK3</i> mutations in juvenile myelomonocytic leukemia using droplet digital PCR

    Wakamatsu Manabu, Okuno Yusuke, Murakami Norihiro, Miwata Shunsuke, Kitazawa Hironobu, Narita Kotaro, Kataoka Shinsuke, Ichikawa Daisuke, Hamada Motoharu, Taniguchi Rieko, Suzuki Kyogo, Kawashima Nozomu, Nishikawa Eri, Narita Atsushi, Nishio Nobuhiro, Kojima Seiji, Muramatsu Hideki, Takahashi Yoshiyuki

    LEUKEMIA   Vol. 35 ( 1 ) page: 259 - 263   2021.1

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    DOI: 10.1038/s41375-020-0817-x

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  110. A Breast-Fed Baby with Low KREC in TREC/KREC Newborn Screening Whose Mother Received Azathioprine Treatment

    Wakamatsu Manabu, Muramatsu Hideki, Kojima Daiei, Okuno Yusuke, Sakai Yoshimi, Nakajima Yoko, Ito Tetsuya, Kawashima Nozomu, Narita Atsushi, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 67   2020.12

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  111. Allogeneic Stem Cell Transplantation from Alternative Donors for Children with Aplastic Anemia

    Narita Atsushi, Muramatsu Hideki, Imaya Masayuki, Yamamori Ayako, Yoshida Taro, Wakamatsu Manabu, Miwata Shunsuke, Narita Koutaro, Kitazawa Hironobu, Taniguchi Rieko, Hamada Motoharu, Ichikawa Daisuke, Nishikawa Eri, Kawashima Nozomu, Okuno Yusuke, Nishio Nobuhiro, Kojima Seiji, Takahashi Yoshiyuki

    BONE MARROW TRANSPLANTATION   Vol. 55 ( SUPPL 1 ) page: 215 - 216   2020.12

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  112. Allogeneic Hematopoietic Cell Transplantation in First Remission in Children with AML: A Comparison of RIC and MAC

    Hama Asahito, Yamashita Daiki, Sajiki Daichi, Kitazawa Hironobu, Sakaguchi Hirotoshi, Yoshida Nao, Kawashima Nozomu, Narita Atsushi, Muramatsu Hideki, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 67   2020.12

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  113. Biomarkers for Distinguishing between acute GVHD and HHV-6B-Associated Skin Rash after Hematopoietic Stem Cell Transplantation

    Miura Hiroki, Kudo Kazuko, Tanaka Makito, Takahashi Yoshiyuki, Kojima Seiji, Yoshikawa Tetsushi

    PEDIATRIC BLOOD & CANCER   Vol. 67   2020.12

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  114. Clinical Features of Cord Colitis Syndrome in Children

    Maemura Ryo, Narita Atsushi, Ichikawa Daisuke, Hamada Motoharu, Nishikawa Eri, Kawashima Nozomu, Nishio Nobuhiro, Muramatsu Hideki, Kojima Seiji, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 67   2020.12

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  115. INFANTILE HEMISPHERIC BRAIN TUMOR WITH A GOPC-ROS1 FUSION GENE: A CASE REPORT

    Taniguchi Rieko, Natsume Atsushi, Kawashima Nozomu, Tanioka Shinji, Muramatsu Hideki, Hamada Motoharu, Ichikawa Daisuke, Imaya Masayuki, Narita Kotaro, Kurimoto Michihiro, Shiba Yoshiki, Aoki Kosuke, Ohka Fumiharu, Hirato Junko, Wakabayashi Toshihiko, Takahashi Yoshiyuki

    NEURO-ONCOLOGY   Vol. 22   page: 377 - 377   2020.12

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  116. Development of Donor-Derived T cell EBV-LPD with Identical EBV Genome after Allogeneic CBT in the NK Cell-Type CAEBV Patient

    Imaya Masayuki, Okuno Yusuke, Kawashima Nozomu, Wakamatsu Manabu, Muramatsu Hideki, Nishio Nobuhiro, Sawada Akihisa, Kawada Junichi, Ito Yoshinori, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 67   2020.12

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  117. Favorable Prognosis of Patients with Intermediate-Risk Neuroblastoma Having Residual Tumor after Treatment

    Nishio Nobuhiro, Ichikawa Daisuke, Hamada Motoharu, Nishikawa Eri, Kawashima Nozomu, Narita Atsushi, Muramatsu Hideki, Kojima Seiji, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 67   2020.12

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  118. Effect of Azacitidine in a Child with Fanconi Anemia and Myelodysplastic Syndrome Harboring Monosomy 7

    Kawashima Nozomu, Ito Masafumi, Narita Kotaro, Ichikawa Daisuke, Nishikawa Eri, Narita Atsushi, Muramatsu Hideki, Nishio Nobuhiro, Kojima Seiji, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 67   2020.12

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  119. Digenic mutations in <i>ALDH2</i> and <i>ADH5</i> impair formaldehyde clearance and cause a multisystem disorder, AMeD syndrome

    Oka Yasuyoshi, Hamada Motoharu, Nakazawa Yuka, Muramatsu Hideki, Okuno Yusuke, Higasa Koichiro, Shimada Mayuko, Takeshima Honoka, Hanada Katsuhiro, Hirano Taichi, Kawakita Toshiro, Sakaguchi Hirotoshi, Ichimura Takuya, Ozono Shuichi, Yuge Kotaro, Watanabe Yoriko, Kotani Yuko, Yamane Mutsumi, Kasugai Yumiko, Tanaka Miyako, Suganami Takayoshi, Nakada Shinichiro, Mitsutake Norisato, Hara Yuichiro, Kato Kohji, Mizuno Seiji, Miyake Noriko, Kawai Yosuke, Tokunaga Katsushi, Nagasaki Masao, Kito Seiji, Isoyama Keiichi, Onodera Masafumi, Kaneko Hideo, Matsumoto Naomichi, Matsuda Fumihiko, Matsuo Keitaro, Takahashi Yoshiyuki, Mashimo Tomoji, Kojima Seiji, Ogi Tomoo

    SCIENCE ADVANCES   Vol. 6 ( 51 )   2020.12

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    DOI: 10.1126/sciadv.abd7197

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  120. Hematopoietic Stem Cell Transplantation for Inborn Errors of Immunity in Japan: Overview of a Nationwide Retrospective Analysis

    Miyamoto Satoshi, Yanagimachi Masakatsu, Umeda Katsutsugu, Iguchi Akihiro, Sasahara Yoji, Takada Hidetoshi, Yamada Masafumi, Ishimura Masataka, Koike Takashi, Yasui Masahiro, Takahashi Yoshiyuki, Kawaguchi Hiroshi, Kajiwara Michiko, Inoue Masami, Kato Koji, Hashii Yoshiko, Atsuta Yoshiko, Yabe Hiromasa, Imai Kohsuke, Morio Tomohiro

    BONE MARROW TRANSPLANTATION   Vol. 55 ( SUPPL 1 ) page: 102 - 103   2020.12

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  121. Hematopoietic Stem Cell Transplantation for Severe Combined Immunodeficiency in Japan: A Nationwide Retrospective Analysis

    Miyamoto Satoshi, Yanagimachi Masakatsu, Umeda Katsutsugu, Iguchi Akihiro, Sasahara Yoji, Takada Hidetoshi, Takahashi Yoshiyuki, Kajiwara Michiko, Inoue Masami, Kato Koji, Hashii Yoshiko, Atsuta Yoshiko, Yabe Hiromasa, Imai Kohsuke, Morio Tomohiro

    BONE MARROW TRANSPLANTATION   Vol. 55 ( SUPPL 1 ) page: 443 - 443   2020.12

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  122. Viral Reactivations in Children with Aplastic Anemia Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

    Narita Atsushi, Ito Yoshinori, Kawashima Nozomu, Okuno Yusuke, Muramatsu Hideki, Nishio Nobuhiro, Torii Yuka, Kawada Junichi, Kojima Seiji, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 67   2020.12

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  123. Microsatellite Instability-High is Rare Events in Refractory Pediatric Solid Tumors

    Yoshida Taro, Muramatsu Hideki, Wakamatsu Manabu, Taniguchi Rieko, Ichikawa Daisuke, Nakaguro Masato, Natsume Atsushi, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 67   2020.12

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  124. Reduced Intensity Conditioning is Effective for Hematopoietic stem Cell Transplantation in Patients with Diamond-Blackfan ANEMIA

    Koyamaishi Shun, Kamio Takuya, Kobayashi Akie, Sato Tomohiko, Kudo Ko, Sasaki Shinya, Kanezaki Rika, Hasegawa Daiichiro, Muramatsu Hideki, Takahashi Yoshiyuki, Sasahara Yoji, Hiramatsu Hidefumi, Kakuda Harumi, Tanaka Miyuki, Ishimura Masataka, Nishi Masanori, Ishiguro Akira, Yabe Hiromasa, Yoshida Kenichi, Kanno Hitoshi, Ohga Shouichi, Ohara Akira, Kojima Seiji, Miyano Satoru, Ogawa Seishi, Toki Tsutomu, Terui Kiminori, Ito Etsuro

    BONE MARROW TRANSPLANTATION   Vol. 55 ( SUPPL 1 ) page: 36 - 37   2020.12

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  125. Strategy of Stem Cell Transplantation at 1st Molecular CR for Pediatric Acute Lymphoblastic Leukemia with MEF2D-BCL9 Fusion

    Hamada Motoharu, Imaya Masayuki, Okuno Yusuke, Ichikawa Daisuke, Kawashima Nozomu, Narita Atsushi, Nishikawa Eri, Muramatsu Hideki, Nishio Nobuhiro, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 67   2020.12

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  126. Myelodysplastic syndromes in a pediatric patient with Cri du Chat syndrome with a ring chromosome 5

    Nozawa Akifumi, Ozeki Michio, Yasue Shiho, Endo Saori, Kadowaki Tomonori, Ohnishi Hidenori, Muramatsu Hideki, Hama Asahito, Takahashi Yoshiyuki, Kojima Seiji, Fukao Toshiyuki

    INTERNATIONAL JOURNAL OF HEMATOLOGY   Vol. 112 ( 5 ) page: 728 - 733   2020.11

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    DOI: 10.1007/s12185-020-02909-7

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  127. Risk factors for secondary poor graft function after bone marrow transplantation in children with acquired aplastic anemia

    Hama Asahito, Muramatsu Hideki, Narita Atsushi, Nishikawa Eri, Kawashima Nozomu, Nishio Nobuhiro, Kojima Seiji, Takahashi Yoshiyuki

    PEDIATRIC TRANSPLANTATION   Vol. 24 ( 7 ) page: e13828   2020.11

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    DOI: 10.1111/petr.13828

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  128. Comprehensive pathogen detection in sera of Kawasaki disease patients by high-throughput sequencing: a retrospective exploratory study

    Torii Yuka, Horiba Kazuhiro, Hayano Satoshi, Kato Taichi, Suzuki Takako, Kawada Jun-ichi, Takahashi Yoshiyuki, Kojima Seiji, Okuno Yusuke, Ogi Tomoo, Ito Yoshinori

    BMC PEDIATRICS   Vol. 20 ( 1 ) page: 482   2020.10

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    DOI: 10.1186/s12887-020-02380-7

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  129. MicroRNA-155-5p Plays a Critical Role in Transient Leukemia of Down Syndrome by Targeting Tumor Necrosis Factor Receptor Superfamily Members.

    Sas V, Pasca S, Jurj A, Pop L, Muramatsu H, Ono H, Dima D, Teodorescu P, Iluta S, Turcas C, Onaciu A, Munteanu R, Zimta AA, Blag C, Popa G, von Gamm EDA, Arghirescu S, Serban M, Man S, Marian M, Petrushev B, Berce C, Colita A, Zdrenghea M, Kojima S, Gulei D, Takahashi Y, Tomuleasa C

    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology   Vol. 54 ( 5 ) page: 994 - 1012   2020.10

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    DOI: 10.33594/000000283

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  130. Change of White Matter Integrity in Children With Hematopoietic Stem Cell Transplantation

    Sakaguchi Yoko, Natsume Jun, Kidokoro Hiroyuki, Tanaka Masaharu, Okai Yu, Ito Yuji, Yamamoto Hiroyuki, Ohno Atsuko, Nakata Tomohiko, Nakane Toshiki, Kawai Hisashi, Taoka Toshiaki, Muramatsu Hideki, Naganawa Shinji, Takahashi Yoshiyuki

    PEDIATRIC NEUROLOGY   Vol. 111   page: 78 - 84   2020.10

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    DOI: 10.1016/j.pediatrneurol.2020.06.008

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  131. Successful treatment with i.v. immunoglobulin and rituximab for bronchiolitis obliterans associated with paraneoplastic pemphigus

    Kaibuchi-Ando Kaori, Sugiura Kazumitsu, Muro Yoshinao, Takahashi Yoshiyuki, Kojima Seiji, Ishii Norito, Hashimoto Takashi, Akiyama Masashi

    JOURNAL OF DERMATOLOGY   Vol. 47 ( 10 ) page: E368 - E370   2020.10

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    DOI: 10.1111/1346-8138.15496

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  132. Direct Delivery of <i>piggyBac</i> CD19 CAR T Cells Has Potent Anti-tumor Activity against ALL Cells in CNS in a Xenograft Mouse Model

    Tanaka Kuniaki, Kato Itaru, Tanaka Miyuki, Morita Daisuke, Matsuda Kazuyuki, Takahashi Yoshiyuki, Nakahata Tatsutoshi, Umeda Katsutsugu, Hiramatsu Hidefumi, Adachi Souichi, Takita Junko, Nakazawa Yozo

    MOLECULAR THERAPY-ONCOLYTICS   Vol. 18   page: 37 - 46   2020.9

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    DOI: 10.1016/j.omto.2020.05.013

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  133. Association between graft source and response to live-attenuated vaccination in pediatric hematopoietic stem cell transplantation recipients: a single-center retrospective study

    Suzuki Takako, Kawada Jun-ichi, Nishikawa Eri, Torii Yuka, Horiba Kazuhiro, Takeuchi Suguru, Okumura Toshihiko, Muramatsu Hideki, Takahashi Yoshiyuki, Ito Yoshinori

    BONE MARROW TRANSPLANTATION   Vol. 55 ( 9 ) page: 1872 - 1874   2020.9

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    DOI: 10.1038/s41409-020-0867-8

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  134. Establishment of a Novel Fetal Growth Restriction Model and Development of a Stem-Cell Therapy Using Umbilical Cord-Derived Mesenchymal Stromal Cells

    Kitase Yuma, Sato Yoshiaki, Arai Sakiko, Onoda Atsuto, Ueda Kazuto, Go Shoji, Mimatsu Haruka, Jabary Mahboba, Suzuki Toshihiko, Ito Miharu, Saito Akiko, Hirakawa Akihiro, Mukai Takeo, Nagamura-Inoue Tokiko, Takahashi Yoshiyuki, Tsuji Masahiro, Hayakawa Masahiro

    FRONTIERS IN CELLULAR NEUROSCIENCE   Vol. 14   page: 212   2020.7

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    DOI: 10.3389/fncel.2020.00212

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  135. Lower limb pain following allogeneic hematopoietic stem cell transplantation in Japanese children

    Mishima Kenichi, Kitoh Hiroshi, Matsushita Masaki, Nagata Tadashi, Kamiya Yasunari, Takahashi Yoshiyuki, Ishiguro Naoki

    JOURNAL OF ORTHOPAEDIC SCIENCE   Vol. 25 ( 4 ) page: 682 - 687   2020.7

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    DOI: 10.1016/j.jos.2019.07.007

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  136. Conditioning regimen for allogeneic bone marrow transplantation in children with acquired bone marrow failure: fludarabine/melphalan vs. fludarabine/cyclophosphamide

    Yoshida Nao, Takahashi Yoshiyuki, Yabe Hiromasa, Kobayashi Ryoji, Watanabe Kenichiro, Kudo Kazuko, Yabe Miharu, Miyamura Takako, Koh Katsuyoshi, Kawaguchi Hiroshi, Goto Hiroaki, Fujita Naoto, Okada Keiko, Okamoto Yasuhiro, Kato Koji, Inoue Masami, Suzuki Ritsuro, Atsuta Yoshiko, Kojima Seiji, Kato Keisuke, Muramatsu Hideki, Narita Atsushi, Wakamatsu Manabu

    BONE MARROW TRANSPLANTATION   Vol. 55 ( 7 ) page: 1272 - 1281   2020.7

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    DOI: 10.1038/s41409-020-0948-8

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  137. Targeting MEF2D-fusion Oncogenic Transcriptional Circuitries in B-cell Precursor Acute Lymphoblastic Leukemia

    Tsuzuki Shinobu, Yasuda Takahiko, Kojima Shinya, Kawazu Masahito, Akahane Koshi, Inukai Takeshi, Imaizumi Masue, Morishita Takanobu, Miyamura Koichi, Ueno Toshihide, Karnan Sivasundaram, Ota Akinobu, Hyodo Toshinori, Konishi Hiroyuki, Sanada Masashi, Nagai Hirokazu, Horibe Keizo, Tomita Akihiro, Suzuki Kyogo, Muramatsu Hideki, Takahashi Yoshiyuki, Miyazaki Yasushi, Matsumura Itaru, Kiyoi Hitoshi, Hosokawa Yoshitaka, Mano Hiroyuki, Hayakawa Fumihiko

    BLOOD CANCER DISCOVERY   Vol. 1 ( 1 ) page: 82 - 95   2020.7

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    DOI: 10.1158/2643-3249.BCD-19-0080

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  138. Targeting MEF2D-fusion Oncogenic Transcriptional Circuitries in B-cell Precursor Acute Lymphoblastic Leukemia.

    Tsuzuki S, Yasuda T, Kojima S, Kawazu M, Akahane K, Inukai T, Imaizumi M, Morishita T, Miyamura K, Ueno T, Karnan S, Ota A, Hyodo T, Konishi H, Sanada M, Nagai H, Horibe K, Tomita A, Suzuki K, Muramatsu H, Takahashi Y, Miyazaki Y, Matsumura I, Kiyoi H, Hosokawa Y, Mano H, Hayakawa F

    Blood cancer discovery   Vol. 1 ( 1 ) page: 82 - 95   2020.7

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    DOI: 10.1158/2643-3230.BCD-19-0080

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  139. Safe diagnostic management of malignant mediastinal tumors in the presence of respiratory distress: a 10-year experience

    Tanaka Tomoko, Amano Hizuru, Tanaka Yujiro, Takahashi Yoshiyuki, Tajiri Tatsuro, Tainaka Takahisa, Shirota Chiyoe, Sumida Wataru, Yokota Kazuki, Makita Satoshi, Tani Yukiko, Hinoki Akinari, Uchida Hiroo

    BMC PEDIATRICS   Vol. 20 ( 1 ) page: 292   2020.6

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    DOI: 10.1186/s12887-020-02183-w

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  140. Impact of graft-versus-host disease on the clinical outcome of allogeneic hematopoietic stem cell transplantation for non-malignant diseases

    Umeda Katsutsugu, Imai Kohsuke, Yanagimachi Masakatsu, Yabe Hiromasa, Kobayashi Masao, Takahashi Yoshiyuki, Kajiwara Michiko, Yoshida Nao, Cho Yuko, Inoue Masami, Hashii Yoshiko, Atsuta Yoshiko, Morio Tomohiro

    INTERNATIONAL JOURNAL OF HEMATOLOGY   Vol. 111 ( 6 ) page: 869 - 876   2020.6

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    DOI: 10.1007/s12185-020-02839-4

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  141. A familial case of alveolar capillary dysplasia with misalignment of the pulmonary veins: the clinicopathological features and unusual glomeruloid endothelial proliferation

    Kitano Akiko, Nakaguro Masato, Tomotaki Seiichi, Hanaoka Shintaro, Kawai Masahiko, Saito Akiko, Hayakawa Masahiro, Takahashi Yoshiyuki, Kawasaki Hidenori, Yamada Takahiro, Ikeda Masahiko, Onda Tetsuo, Cho Kazutoshi, Haga Hironori, Nakazawa Atsuko, Minamiguchi Sachiko

    DIAGNOSTIC PATHOLOGY   Vol. 15 ( 1 ) page: 48   2020.5

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    DOI: 10.1186/s13000-020-00972-6

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  142. Clinical Outcomes after Allogeneic Hematopoietic Stem Cell Transplantation in Children with Juvenile Myelomonocytic Leukemia: A Report from the Japan Society for Hematopoietic Cell Transplantation

    Yoshida Nao, Sakaguchi Hirotoshi, Yabe Miharu, Hasegawa Daiichiro, Hama Asahito, Hasegawa Daisuke, Kato Motohiro, Noguchi Maiko, Terui Kiminori, Takahashi Yoshiyuki, Cho Yuko, Sato Maho, Koh Katsuyoshi, Kakuda Harumi, Shimada Hiroyuki, Hashii Yoshiko, Sato Atsushi, Kato Koji, Atsuta Yoshiko, Watanabe Kenichiro

    BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION   Vol. 26 ( 5 ) page: 902 - 910   2020.5

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    DOI: 10.1016/j.bbmt.2019.11.029

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  143. Autologous Stem Cell Transplantation for Children With Renal Tumors, and Adults With Wilms Tumor: Retrospective Analysis of the Japanese Transplant Registry Unified Management Program

    Kobayashi Ryoji, Inoue Masami, Takahashi Yoshiyuki, Kikuta Atsushi, Ogawa Atsushi, Koga Yuhki, Koh Katsuyoshi, Hashii Yoshiko, Hara Junichi, Kato Koji, Tabuchi Ken, Matsumoto Kimikazu

    JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY   Vol. 42 ( 4 ) page: 251 - 255   2020.5

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    DOI: 10.1097/MPH.0000000000001779

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  144. Biallelic VPS35L pathogenic variants cause 3C/Ritscher-Schinzel-like syndrome through dysfunction of retriever complex

    Kato Kohji, Oka Yasuyoshi, Muramatsu Hideki, Vasilev Filipp F., Otomo Takanobu, Oishi Hisashi, Kawano Yoshihiko, Kidokoro Hiroyuki, Nakazawa Yuka, Ogi Tomoo, Takahashi Yoshiyuki, Saitoh Shinji

    JOURNAL OF MEDICAL GENETICS   Vol. 57 ( 4 ) page: 245 - 253   2020.4

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    DOI: 10.1136/jmedgenet-2019-106213

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  145. Mesenchymal stem/stromal cells stably transduced with an inhibitor of CC chemokine ligand 2 ameliorate bronchopulmonary dysplasia and pulmonary hypertension

    Suzuki Toshihiko, Sato Yoshiaki, Yamamoto Hidenori, Kato Taichi, Kitase Yuma, Ueda Kazuto, Mimatsu Haruka, Sugiyama Yuichiro, Onoda Atsuto, Saito Shigeki, Takahashi Yoshiyuki, Nakayama Takayuki, Hayakawa Masahiro

    CYTOTHERAPY   Vol. 22 ( 4 ) page: 180 - 192   2020.4

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    DOI: 10.1016/j.jcyt.2020.01.009

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  146. Clinical Characteristics and Treatment Outcomes of Pediatric Patients with Non-Hodgkin Lymphoma in East Asia

    Suh Jin Kyung, Gao Yi-Jin, Tang Jing-Yan, Jou Shiann-Tarng, Lin Dong-Tsamn, Takahashi Yoshiyuki, Kojima Seiji, Jin Ling, Zhang Yonghong, Seo Jong Jin

    CANCER RESEARCH AND TREATMENT   Vol. 52 ( 2 ) page: 359 - 368   2020.4

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    DOI: 10.4143/crt.2019.219

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  147. Novel compound heterozygous <i>MCOLN1</i> mutations identified in a Japanese girl with severe developmental delay and thin corpus callosum

    Yamaguchi Naoya, Ban Kyoko, Suzuki Atsushi, Nakamura Yuji, Kato Kohji, Muramatsu Hideki, Okuno Yusuke, Hattori Ayako, Kaname Tadashi, Takahashi Yoshiyuki, Saitoh Shinji

    BRAIN & DEVELOPMENT   Vol. 42 ( 3 ) page: 298 - 301   2020.3

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    DOI: 10.1016/j.braindev.2019.12.003

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  148. Respiratory illness and acute flaccid myelitis in the Tokai district in 2018

    Okumura Akihisa, Numoto Shingo, Iwayama Hideyuki, Kurahashi Hirokazu, Natsume Jun, Saitoh Shinji, Yoshikawa Tetsushi, Fukao Toshiyuki, Hirayama Masahiro, Takahashi Yoshiyuki

    PEDIATRICS INTERNATIONAL   Vol. 62 ( 3 ) page: 337 - 340   2020.3

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    DOI: 10.1111/ped.14128

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  149. Human herpesvirus-6B infection in pediatric allogenic hematopoietic stem cell transplant patients: Risk factors and encephalitis

    Miura Hiroki, Kawamura Yoshiki, Hattori Fumihiko, Tanaka Makito, Kudo Kazuko, Ihira Masaru, Yatsuya Hiroshi, Takahashi Yoshiyuki, Kojima Seiji, Sakaguchi Hirotoshi, Yoshida Nao, Hama Asahito, Yoshikawa Tetsushi

    TRANSPLANT INFECTIOUS DISEASE   Vol. 22 ( 1 ) page: e13203   2020.2

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    DOI: 10.1111/tid.13203

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  150. Pseudo-sawtooth pattern on amplitude-integrated electroencephalography in neonatal hypoxic-ischemic encephalopathy

    Tanaka Masaharu, Kidokoro Hiroyuki, Kubota Tetsuo, Fukasawa Tatsuya, Okai Yu, Sakaguchi Yoko, Ito Yuji, Yamamoto Hiroyuki, Ohno Atsuko, Nakata Tomohiko, Negoro Tamiko, Okumura Akihisa, Kato Toru, Watanabe Kazuyoshi, Takahashi Yoshiyuki, Natsume Jun

    PEDIATRIC RESEARCH   Vol. 87 ( 3 ) page: 529 - 535   2020.2

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    DOI: 10.1038/s41390-019-0567-5

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  151. Targetable driver mutations in multicentric reticulohistiocytosis

    Murakami Norihiro, Sakai Tomohisa, Arai Eisuke, Muramatsu Hideki, Ichikawa Daisuke, Asai Shuji, Shimoyama Yoshie, Ishiguro Naoki, Takahashi Yoshiyuki, Okuno Yusuke, Nishida Yoshihiro

    HAEMATOLOGICA   Vol. 105 ( 2 ) page: E61 - E64   2020.1

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    DOI: 10.3324/haematol.2019.218735

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  152. A Novel Treatment with Stem Cells from Human Exfoliated Deciduous Teeth for Hypoxic-Ischemic Encephalopathy in Neonatal Rats

    Kitase Yuma, Sato Yoshiaki, Ueda Kazuto, Suzuki Toshihiko, Mikrogeorgiou Alkisti, Sugiyama Yuichiro, Matsubara Kohki, Okabe Yuka Tsukagoshi, Shimizu Shinobu, Hirata Hitoshi, Yukawa Hiroshi, Baba Yoshinobu, Tsuji Masahiro, Takahashi Yoshiyuki, Yamamoto Akihito, Hayakawa Masahiro

    STEM CELLS AND DEVELOPMENT   Vol. 29 ( 2 ) page: 63 - 74   2020.1

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    DOI: 10.1089/scd.2019.0221

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  153. A Case of a 14-Year-Old Boy who had Difficulty Walking Due to Drug-Induced Neuropathy During T-Cell Acute Lymphocytic Leukemia Treatment

    Yoshida Taro, Sawamura Aya, Muramatsu Hideki, Imaya Masayuki, Yamamori Ayako, Wakamatsu Manabu, Miwata Shunsuke, Narita Kotaro, Kitazawa Hironobu, Taniguchi Rieko, Ichikawa Daisuke, Nishikawa Eri, Hamada Motoharu, Kawashima Nozomu, Narita Atsushi, Nishio Nobuhiro, Kojima Seiji, Nakata Tomohiko, Kidokoro Hiroyuki, Natxume Jun, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 66   page: S30 - S30   2019.12

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  154. A CaseWith Dyskeratosis Congenita Achieved Transfusion Independence after Eltrombopag Treatment

    Wakamatsu Manabu, Muramatsu Hideki, Imaya Masayuki, Yamamori Ayako, Yoshida Taro, Miwata Shunsuke, Kitazawa Hironobu, Narita Kotaro, Ichikawa Disuke, Hamada Motoharu, Taniguchi Rieko, Kawasima Nozomu, Nishikawa Eri, Narita Atsushi, Okuno Yusuke, Nishio Nobuhiro, Kojima Seiji, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 66   page: S46 - S46   2019.12

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  155. Clinical and Laboratory Characteristics of Atypical Chronic Myeloid Leukemia and Chronic Myelomonocytic Leukemia in Japanese Children

    Hama Asahito, Ito Masafumi, Hasegawa Daisuke, Nozawa Kazue, Muramatsu Hideki, Takahashi Yoshiyuki, Watanabe Kenichiro, Ohara Akira, Manabe Atsushi, Kojima Seiji

    PEDIATRIC BLOOD & CANCER   Vol. 66   page: S21 - S22   2019.12

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  156. An Infant With Hereditary Folate Malabsorption Requiring Differentiation from Acute Megakaryoblastic Leukemia

    Nishikawa Eri, Taniguchi Rieko, Yoshida Tarou, Imaya Masayuki, Wakamatsu Manabu, Miwata Syunsuke, Narita Koutarou, Yamamori Ayako, Kitazawa Hironobu, Ichikawa Daisuke, Hamada Motoharu, Kawashima Nozomu, Narita Atsushi, Okuno Yusuke, Muramatsu Hideki, Nishio Nobuhiro, Kojima Seiji, Said Shimaa, Tozawa Yusuke, Yamada Masafumi, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 66   page: S73 - S73   2019.12

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  157. Identification of <i>FANCI</i> Mutation in Fanconi Anemia in Infancy

    Urata Takayo, Imamura Toshihiko, Osone Shinya, Muramatsu Hideki, Takahashi Yoshiyuki, Hosoi Hajime

    PEDIATRIC BLOOD & CANCER   Vol. 66   page: S44 - S44   2019.12

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  158. Integrating FANCD2 Functional Analysis With High-Throughput Sequencing for Diagnosing Fanconi Anemia

    Kawashima Nozomu, Okuno Yusuke, Muramatsu Hideki, Taniguchi Rieko, Yoshida Taro, Imaya Masayuki, Yamamori Ayako, Wakamatsu Manabu, Miwata Shunsuke, Narita Kotaro, Hamada Motoharu, Ichikawa Daisuke, Kitazawa Nobuhiro, Nishikawa Eri, Narita Atsushi, Nishio Nobuhiro, Kojima Seiji, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 66   page: S44 - S45   2019.12

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  159. Induction of Partial Response With Ceritinib for a Child With Chemotherapy-Refractory ALK-rearranged Neuroblastoma

    Narita Kotaro, Yoshida Taro, Yamamori Ayako, Wakamatsu Manabu, Imaya Masayuki, Miwata Shunsuke, Kitazawa Hironobu, Taniguchi Rieko, Ichikawa Daisuke, Hamada Motoharu, Nishikawa Eri, Nishio Nobuhiro, Okuno Yusuke, Kawashima Nozomu, Narita Atsushi, Muramatsu Hideki, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 66   page: S104 - S104   2019.12

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  160. Conditioning Regimen for Allogeneic Bone Marrow Transplantation in Children With Acquired Bone Marrow Failure: Fludarabine/Melphalan vs. Fludarabine/Cyclophosphamide

    Yoshida Nao, Takahashi Yoshiyuki, Yabe Hiromasa, Kobayashi Ryoji, Watanabe Kenichiro, Kudo Kazuko, Yabe Miharu, Miyamura Takako, Koh Katsuyoshi, Kawaguchi Hiroshi, Goto Hiroaki, Fujita Naoto, Hara Junichi, Okamoto Yasuhiro, Kato Koji, Inoue Masami, Suzuki Ritsuro, Atsuta Yoshiko, Kojima Seiji

    PEDIATRIC BLOOD & CANCER   Vol. 66   page: S95 - S95   2019.12

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  161. Genetic Diagnosis Based on a Comprehensive Fusion Gene Analysis of Pediatric Malignant Solid Tumors

    Ichikawa Daisuke, Muramatsu Hideki, Okuno Yusuke, Hamada Motoharu, Taniguchi Rieko, Nishikawa Eri, Kawashima Nozomu, Narita Atsushi, Nishio Nobuhiro, Shimoyama Yoshie, Nakaguro Masato, Nakamura Shigeo, Kojima Seiji, Nakazawa Atsuko, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 66   page: S61 - S61   2019.12

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  162. Evaluation of the Outcome of KIR-Ligand Mismatched Cord Blood Transplantation for High Risk Metastatic Neuroblastoma Using New SIOPEN Risk Stratification

    Nishio Nobuhiro, Ichikawa Daisuke, Wakamatsu Manabu, Narita Kotaro, Miwata Shunsuke, Kitazawa Hironobu, Taniguchi Rieko, Hamada Motoharu, Nishikawa Eri, Kawashima Nozomu, Okuno Yusuke, Narita Atsushi, Muramatsu Hideki, Kojima Seiji, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 66   page: S106 - S106   2019.12

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  163. Correlation Between Plasma Rabbit Anti-Thymocyte Globulin Level and Response to Immunosuppressive Therapy in Patients With Severe Aplastic Anemia

    Narita Atsushi, Muramatsu Hideki, Hamada Motoharu, Ichikawa Daisuke, Nishikawa Eri, Kawashima Nozomu, Okuno Yusuke, Nishio Nobuhiro, Yamazaki Hirohito, Nakao Shinji, Kojima Seiji, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 66   page: S45 - S45   2019.12

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  164. Two Cases Effectively Treated with Oral Budesonide Administration for Steroid-resistant Intestinal Acute Graft Versus Host Disease

    Yamamori Ayako, Nishikawa Eri, Narita Atsushi, Imaya Masayuki, Wakamatsu Manabu, Yoshida Taro, Miwata Shunsuke, Kitazawa Hironobu, Narita Kotaro, Taniguchi Rieko, Ichikawa Daisuke, Hamada Motoharu, Kawashima Nozomu, Okuno Yusuke, Nishio Nobuhiro, Muramatsu Hideki, Kojima Seiji, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 66   page: S37 - S38   2019.12

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  165. Whole Exome Sequencing Contributes to Genetic Diagnosis of IBMFS Patients

    Muramatsu Hideki, Hamada Motoharu, Okuno Yusuke, Wakamatsu Manabu, Taniguchi Rieko, Narita Koutarou, Kawashima Nozomu, Kitazawa Hironobu, Ichikawa Daisuke, Nishikawa Eri, Kawashima Nazomu, Narita Atsushi, Nishio Nobuhiro, Kojima Seiji, Ogi Tomoo, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 66   page: S63 - S64   2019.12

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  166. Prediction of postnatal clinical course in primary congenital dilated cardiomyopathy

    Yamamoto Hidenori, Fukasawa Yoshie, Ohashi Naoki, Yokoyama Takehiko, Suzuki Kazutaka, Ota Takaya, Yasuda Kazushi, Omoya Kentaro, Takahashi Yoshiyuki, Kato Taichi

    PEDIATRICS INTERNATIONAL   Vol. 61 ( 12 ) page: 1196 - 1201   2019.12

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    DOI: 10.1111/ped.14029

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  167. Successful Treatment of Central Nervous System Relapses of Neuroblastoma Stage 4 After a KIR-ligand Mismatched Allogeneic Cord Blood Transplantation

    Imaya Masayuki, Narita Atsushi, Yoshida Taro, Yamamori Ayako, Wakamatsu Manabu, Miwata Syunsuke, Narita Kotaro, Kitazawa Hironobu, Taniguchi Rieko, Ichikawa Daisuke, Hamada Motoharu, Nishikawa Eri, Kawashima Nozomu, Muramatsu Hideki, Nishio Nobuhiro, Kojima Seiji, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 66   page: S102 - S102   2019.12

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  168. Successfully Treated Three Children With Pericardial Effusion After Hematopoietic Stem Cell Transplantation

    Kitazawa Hironobu, Narita Atsushi, Yoshida Taro, Imaya Masayuki, Yamamori Ayako, Wakamatsu Manabu, Miwata Shunsuke, Narita Kotaro, Taniguchi Rieko, Hamada Motoharu, Ichikawa Daisuke, Nishikawa Eri, Kawashima Nozomu, Okuno Yusuke, Nishio Nobuhiro, Muramatsu Hideki, Kojima Seiji, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 66   page: S97 - S97   2019.12

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  169. Comprehensive Mutational Analysis of Juvenile Myelomonocytic Leukemia Using Whole-Genome Sequencing

    Okuno Yusuke, Muramatsu Hideki, Murakami Norihiro, Kawashima Nozomu, Wakamatsu Manabu, Kitazawa Hironobu, Ogi Tomoo, Takahashi Yoshiyuki

    BLOOD   Vol. 134   2019.11

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    DOI: 10.1182/blood-2019-121681

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  170. Genome-Wide Methylation Analysis Using the Digital Restriction Enzyme Analysis of Methylation for Stratification of Patients with Juvenile Myelomonocytic Leukemia

    Kitazawa Hironobu, Muramatsu Hideki, Murakami Norihiro, Okuno Yusuke, Wakamatsu Manabu, Yoshida Taro, Imaya Masayuki, Yamamori Ayako, Miwata Shunsuke, Narita Kotaro, Hamada Motoharu, Ichikawa Daisuke, Taniguchi Rieko, Kawashima Nozomu, Nishikawa Eri, Narita Atsushi, Nishio Nobuhiro, Kojima Seiji, Takahashi Yoshiyuki

    BLOOD   Vol. 134   2019.11

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    DOI: 10.1182/blood-2019-127792

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  171. DNA Methylation As a Biomarker of Outcome in JMML: An International Effort Towards Clinical Implementation

    Meyer Julia, Schoenung Maximillian, Flotho Christian, Olshen Adam B., Hartmann Mark, Plass Christoph, Okuno Yusuke, Takahashi Yoshiyuki, Murakami Norihiro, Wakamatsu Manabu, Loh Mignon L., Niemeyer Charlotte M., Muramatsu Hideki, Lipka Daniel B., Stieglitz Elliot

    BLOOD   Vol. 134   2019.11

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    DOI: 10.1182/blood-2019-131279

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  172. Detection of Subclonal <i>SETBP1</i> and <i>JAK3</i> Mutations in Patients with Juvenile Myelomonocytic Leukemia Using Droplet Digital PCR

    Wakamatsu Manabu, Muramatsu Hideki, Murakami Norihiro, Okuno Yusuke, Kitazawa Hironobu, Kojima Seiji, Takahashi Yoshiyuki

    BLOOD   Vol. 134   2019.11

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    DOI: 10.1182/blood-2019-125354

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  173. High Natural Killer Cell Count at Diagnosis Predicts a Good Response to Immunosuppressive Therapy in Aplastic Anemia

    Narita Atsushi, Muramatsu Hideki, Xu Yinyan, Hamada Motoharu, Ichikawa Daisuke, Nishikawa Eri, Kawashima Nozomu, Okuno Yusuke, Nishio Nobuhiro, Yamazaki Hirohito, Nakao Shinji, Kojima Seiji, Takahashi Yoshiyuki

    BLOOD   Vol. 134   2019.11

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    DOI: 10.1182/blood-2019-124945

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  174. Utility of Newborn Screening for Severe Combined Immunodeficiency and X-Linked Agammaglobulinemia Using TREC and KREC Assays

    Wakamatsu Manabu, Muramatsu Hideki, Kataoka Shinsuke, Okuno Yusuke, Yoshimi Sakai, Nakajima Yoko, Ito Tetsuya, Tsuge Ikuya, Kojima Seiji, Takahashi Yoshiyuki

    BLOOD   Vol. 134   2019.11

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    DOI: 10.1182/blood-2019-126669

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  175. Phase I Study of Cord Blood Transplantation with Intra-Bone Marrow Injection of Mesenchymal Stem Cells

    Goto Tatsunori, Murata Makoto, Nishida Tetsuya, Terakura Seitaro, Kamoshita Sonoko, Ishikawa Yuichi, Ushijima Yoko, Adachi Yoshiya, Kato Katsuyoshi, Hirakawa Akihiro, Nishiwaki Satoshi, Nishio Nobuhiro, Takahashi Yoshiyuki, Kodera Yoshihisa, Matsushita Tadashi, Kiyoi Hitoshi

    BLOOD   Vol. 134   2019.11

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    DOI: 10.1182/blood-2019-122101

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  176. Frequent intragenic microdeletions of elastin in familial supravalvul araortic stenosis (vol 274, pg 290, 2019)

    Hayano Satoshi, Okuno Yusuke, Tsutsumi Makiko, Inagaki Hidehito, Fukasawa Yoshie, Kurahashi Hiroki, Kojima Seiji, Takahashi Yoshiyuki, Kato Taichi

    INTERNATIONAL JOURNAL OF CARDIOLOGY   Vol. 292   page: 283 - 283   2019.10

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    DOI: 10.1016/j.ijcard.2019.06.020

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  177. Prospective randomized trial comparing two doses of rabbit anti-thymocyte globulin in patients with severe aplastic anaemia

    Narita Atsushi, Zhu Xiaofan, Muramatsu Hideki, Chen Xiaojuan, Guo Ye, Yang Wenyu, Zhang Jingliao, Liu Fang, Jang Jun H., Kook Hoon, Kim Hawk, Usuki Kensuke, Yamazaki Hirohito, Takahashi Yoshiyuki, Nakao Shinji, Lee Jong Wook, Kojima Seiji

    BRITISH JOURNAL OF HAEMATOLOGY   Vol. 187 ( 2 ) page: 227 - 237   2019.10

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    DOI: 10.1111/bjh.16055

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  178. Retrospective analysis of children with high-risk acute myeloid leukemia who underwent allogeneic hematopoietic stem cell transplantation following complete remission with initial induction chemotherapy in the AML-05 clinical trial

    Hyakuna Nobuyuki, Hashii Yoshiko, Ishida Hiroyuki, Umeda Katsutsugu, Takahashi Yoshiyuki, Nagasawa Masayuki, Yabe Hiromasa, Nakazawa Yozo, Koh Katsuyoshi, Goto Hiroaki, Fujisaki Hiroyuki, Matsumoto Kimikazu, Kakuda Harumi, Yano Michihiro, Tawa Akio, Tomizawa Daisuke, Taga Takashi, Adachi Souichi, Kato Koji

    PEDIATRIC BLOOD & CANCER   Vol. 66 ( 10 ) page: e27875   2019.10

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    DOI: 10.1002/pbc.27875

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  179. A novel <i>CUL4B</i> splice site variant in a young male exhibiting less pronounced features

    Nakamura Yuji, Okuno Yusuke, Muramatsu Hideki, Kawai Tomoko, Satou Kazuhito, Ieda Daisuke, Hori Ikumi, Ohashi Kei, Negishi Yutaka, Hattori Ayako, Takahashi Yoshiyuki, Kojima Seiji, Saitoh Shinji

    HUMAN GENOME VARIATION   Vol. 6   page: 43   2019.9

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    DOI: 10.1038/s41439-019-0074-6

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  180. Delayed recognition of childhood arterial ischemic stroke

    Hori Ikumi, Tsuji Takeshi, Miyake Misa, Ueda Kazuto, Kataoka Erina, Suzuki Michio, Kobayashi Satoru, Kurahashi Hirokazu, Takahashi Yoshiyuki, Okumura Akihisa, Yoshikawa Tetsushi, Saitoh Shinji, Natsume Jun

    PEDIATRICS INTERNATIONAL   Vol. 61 ( 9 ) page: 895 - 903   2019.9

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    DOI: 10.1111/ped.13966

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  181. Risk factors for absence of catch-up growth in small for gestational age very low-birthweight infants

    Arai Sakiko, Sato Yoshiaki, Muramatsu Hideki, Yamamoto Hidenori, Aoki Fumiko, Okai Yu, Kataoka Shinsuke, Hanada Yu, Hamada Motoharu, Morimoto Yoshihito, Kojima Seiji, Natsume Jun, Takahashi Yoshiyuki, Sugiyama Yuichiro, Hoshino Shin, Kawada Junichi, Kidokoro Hiroyuki, Hayakawa Masahiro, Hattori Tetsuo, Kato Yuichi, Yasuda Ayako, Oshiro Makoto, Takemoto Koji, Nishimura Naoko, Hayashi Seiji, Hyodo Reina, Ito Masatoki, Narahara Shou, Ieda Kuniko, Yamamoto Hikaru

    PEDIATRICS INTERNATIONAL   Vol. 61 ( 9 ) page: 889 - 894   2019.9

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    DOI: 10.1111/ped.13939

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  182. Constitutive activation of mTORC1 signaling induced by biallelic loss-of-function mutations in <i>SZT2</i> underlies a discernible neurodevelopmental disease

    Nakamura Yuji, Kato Kohji, Tsuchida Naomi, Matsumoto Naomichi, Takahashi Yoshiyuki, Saitoh Shinji

    PLOS ONE   Vol. 14 ( 8 ) page: e0221482   2019.8

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    DOI: 10.1371/journal.pone.0221482

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  183. Impact of low-dose irradiation and in vivo T-cell depletion on hematopoietic stem cell transplantation for non-malignant diseases using fludarabine-based reduced-intensity conditioning

    Umeda Katsutsugu, Yabe Hiromasa, Kato Koji, Imai Kohsuke, Kobayashi Masao, Takahashi Yoshiyuki, Yoshida Nao, Sato Maho, Sasahara Yoji, Kato Keisuke, Adachi Souichi, Koga Yuhki, Okada Keiko, Inoue Masami, Hashii Yoshiko, Atsuta Yoshiko, Morio Tomohiro

    BONE MARROW TRANSPLANTATION   Vol. 54 ( 8 ) page: 1227 - 1236   2019.8

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    DOI: 10.1038/s41409-018-0418-8

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  184. Whole abdominopelvic intensity-modulated radiation therapy for peritoneal disseminated rhabdomyosarcoma with three-year follow-up: a case report

    Kawamura Mariko, Okudaira Kuniyasu, Itoh Yoshiyuki, Kamomae Takeshi, Nishikawa Eri, Muramatsu Hideki, Takahashi Yoshiyuki, Yokota Kazuki, Naganawa Shinji

    RADIATION ONCOLOGY   Vol. 14 ( 1 ) page: 127   2019.7

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    DOI: 10.1186/s13014-019-1333-x

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  185. Comparison of Clinical Characteristics of Human Metapneumovirus and Respiratory Syncytial Virus Infections in Hospitalized Young Children

    Taniguchi Akinobu, Kawada Jun-ichi, Go Kiyotaka, Fujishiro Naozumi, Hosokawa Yosuke, Maki Yuki, Sugiyama Yuichiro, Suzuki Michio, Tsuji Takeshi, Hoshino Shin, Muramatsu Hideki, Kidokoro Hiroyuki, Kinoshita Fumie, Hirakawa Akihiro, Takahashi Yoshiyuki, Sato Yoshiaki, Natsume Jun, Yamakawa Kiyoshi, Okumura Akihisa, Kato Toru, Nagai Noriko, Moriyama Miyako, Miyajima Yuji, Yamamori Kazuki, Shibata Motohiro, Hasegawa Masayuki, Shinohara Osamu, Nishimura Naoko, Aoshima Tsutomu, Morishita Masashi, Nomura Yoji, Kuraishi Kenji

    JAPANESE JOURNAL OF INFECTIOUS DISEASES   Vol. 72 ( 4 ) page: 237 - 242   2019.7

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    DOI: 10.7883/yoken.JJID.2018.480

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  186. Effects of HLA mismatch on cytomegalovirus reactivation in cord blood transplantation

    Yokoyama Hisayuki, Kanda Junya, Kato Shunichi, Kondo Eisei, Maeda Yoshinobu, Saji Hiroo, Takahashi Satoshi, Onizuka Makoto, Onishi Yasushi, Ozawa Yukiyasu, Kanamori Heiwa, Ishikawa Jun, Ohno Yuju, Ichinohe Tatsuo, Takanashi Minoko, Kato Koji, Atsuta Yoshiko, Kanda Yoshinobu, Ikegame Kazuhiro, Utsunomiya Atae, Kawase Takakazu, Kim Sung-Won, Kuwatsuka Yachiyo, Kobayashi Takeshi, Takatsuka Yoshifusa, Takahashi Yoshiyuki, Tanaka Junji, Tamaki Hiroya, Tsuji Masanori, Nishida Tetsuya, Masuko Masayoshi, Matsuno Ryosuke, Murata Makoto, Morishima Satoko, Morishima Yasuo, Yokoyama Hisayuki, Wake Atsushi, Watanabe Nobuhiro, Ashida T., Hoshino Takumi, Yabe Toshio, Sakamoto Kana, Fuji Shigeo, Miyamura Koichi, Arima Nobuyoshi, Kondo Eisei, Yoshimitsu Makoto, Kawamura Koji, Kawata Takahito, Kishimoto Kenji, Tatara Raine, Hagino Takeshi, Fujiwara Shin-Ichiro, Shimomura Yoshimitsu, Sakaguchi Hirotoshi, Hirabayashi Shigeki, Ishii Hiroto, Onda Yoshiyuki, Kato Itaru, Kawajiri Akihisa, Shindo Takero, Tokunaga Masahito, Nonami Atsushi, Muranushi Hiroyuki, Yoshinaga Noriyoshi, Kawashima Naomi, Shiratori Souichi, Tada Yuma, Tanoue Sus-Umu, Hirayama Masahiro, Fukunaga Keiko, Ohbiki Marie

    BONE MARROW TRANSPLANTATION   Vol. 54 ( 7 ) page: 1004 - 1012   2019.7

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    DOI: 10.1038/s41409-018-0369-0

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  187. Relationship between plasma rabbit anti-thymocyte globulin level and response to immunosuppressive therapy in patients with severe aplastic anemia: Results of a multicenter, prospective, randomized study

    Narita Atsushi, Muramatsu Hideki, Xu Yinyan, Nishikawa Eri, Kawashima Nozomu, Okuno Yusuke, Nishio Nobuhiro, Hama Asahito, Yamazaki Hirohito, Nakao Shinji, Kojima Seiji, Takahashi Yoshiyuki

    BONE MARROW TRANSPLANTATION   Vol. 54   page: 29 - 29   2019.7

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  188. <i>MYCN</i> de novo gain-of-function mutation in a patient with a novel megalencephaly syndrome

    Kato Kohji, Miya Fuyuki, Hamada Nanako, Negishi Yutaka, Narumi-Kishimoto Yoko, Ozawa Hiroshi, Ito Hidenori, Hori Ikumi, Hattori Ayako, Okamoto Nobuhiko, Kato Mitsuhiro, Tsunoda Tatsuhiko, Kanemura Yonehiro, Kosaki Kenjiro, Takahashi Yoshiyuki, Nagata Koh-ichi, Saitoh Shinji

    JOURNAL OF MEDICAL GENETICS   Vol. 56 ( 6 ) page: 388 - 395   2019.6

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    DOI: 10.1136/jmedgenet-2018-105487

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  189. Comparison of high-dose and low-dose corticosteroid therapy for refractory Mycoplasma pneumoniae pneumonia in children.

    Okumura T, Kawada JI, Tanaka M, Narita K, Ishiguro T, Hirayama Y, Narahara S, Tsuji G, Sugiyama Y, Suzuki M, Tsuji T, Hoshino S, Nakatochi M, Muramatsu H, Kidokoro H, Takahashi Y, Sato Y, Nagoya Collaborative Clinical Research Team.

    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy   Vol. 25 ( 5 ) page: 346 - 350   2019.5

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    DOI: 10.1016/j.jiac.2019.01.003

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  190. High rates of ovarian function preservation after hematopoietic cell transplantation with melphalan-based reduced intensity conditioning for pediatric acute leukemia: an analysis from the Japan Association of Childhood Leukemia Study (JACLS)

    Fujino Hisanori, Ishida Hiroyuki, Iguchi Akihiro, Onuma Masaei, Kato Koji, Shimizu Mariko, Yasui Masahiro, Fujisaki Hiroyuki, Hamamoto Kazuko, Washio Kana, Sakaguchi Hirotoshi, Miyashita Emiko, Osugi Yuko, Nakagami-Yamaguchi Etsuko, Hayakawa Akira, Sato Atsushi, Takahashi Yoshiyuki, Horibe Keizo

    INTERNATIONAL JOURNAL OF HEMATOLOGY   Vol. 109 ( 5 ) page: 578 - 583   2019.5

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    DOI: 10.1007/s12185-019-02627-9

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  191. Design of a prospective multicenter randomized controlled trial evaluating the effects of gastric lavage on coffee-ground emesis in neonates: study protocol

    Maeda Takashi, Sato Yoshiaki, Hirakawa Akihiro, Nakatochi Masahiro, Kinoshita Fumie, Suzuki Takeshi, Ichimura Shintaro, Ito Ryoichi, Kudo Ryuji, Suzuki Michio, Hoshino Shin, Sugiyama Yuichiro, Muramatsu Hideki, Kidokoro Hiroyuki, Kawada Jun-ichi, Takahashi Yoshiyuki, Hayakawa Masahiro, Kato Yuichi, Oshiro Makoto, Hayashi Seiji, Tachibana Takashi, Ieda Kuniko, Yamamoto Hikaru, Takemoto Koji

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 81 ( 2 ) page: 227 - 232   2019.5

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    DOI: 10.18999/nagjms.81.2.227

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  192. Successful hematopoietic stem cell transplantation from an HLA-mismatched parent for engraftment failure after unrelated cord blood transplantation in patients with juvenile myelomonocytic leukemia: Report of two cases

    Akahane Koshi, Watanabe Atsushi, Furuichi Yoshiyuki, Somazu Shinpei, Oshiro Hiroko, Goi Kumiko, Sakashita Kazuo, Muramatsu Hideki, Hama Asahito, Takahashi Yoshiyuki, Koike Kenichi, Kojima Seiji, Sugita Kanji, Inukai Takeshi

    PEDIATRIC TRANSPLANTATION   Vol. 23 ( 3 ) page: e13378   2019.5

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    DOI: 10.1111/petr.13378

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  193. Defective Epstein-Barr virus in chronic active infection and haematological malignancy

    Okuno Yusuke, Murata Takayuki, Sato Yoshitaka, Muramatsu Hideki, Ito Yoshinori, Watanabe Takahiro, Okuno Tatsuya, Murakami Norihiro, Yoshida Kenichi, Sawada Akihisa, Inoue Masami, Kawa Keisei, Seto Masao, Ohshima Koichi, Shiraishi Yuichi, Chiba Kenichi, Tanaka Hiroko, Miyano Satoru, Narita Yohei, Yoshida Masahiro, Goshima Fumi, Kawada Jun-Ichi, Nishida Tetsuya, Kiyoi Hitoshi, Kato Seiichi, Nakamura Shigeo, Morishima Satoko, Yoshikawa Tetsushi, Fujiwara Shigeyoshi, Shimizu Norio, Isobe Yasushi, Noguchi Masaaki, Kikuta Atsushi, Iwatsuki Keiji, Takahashi Yoshiyuki, Kojima Seiji, Ogawa Seishi, Kimura Hiroshi

    NATURE MICROBIOLOGY   Vol. 4 ( 3 ) page: 404 - 413   2019.3

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    DOI: 10.1038/s41564-018-0334-0

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  194. Publisher Correction: Defective Epstein-Barr virus in chronic active infection and haematological malignancy.

    Okuno Y, Murata T, Sato Y, Muramatsu H, Ito Y, Watanabe T, Okuno T, Murakami N, Yoshida K, Sawada A, Inoue M, Kawa K, Seto M, Ohshima K, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Narita Y, Yoshida M, Goshima F, Kawada JI, Nishida T, Kiyoi H, Kato S, Nakamura S, Morishima S, Yoshikawa T, Fujiwara S, Shimizu N, Isobe Y, Noguchi M, Kikuta A, Iwatsuki K, Takahashi Y, Kojima S, Ogawa S, Kimura H

    Nature microbiology   Vol. 4 ( 3 ) page: 544   2019.3

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    DOI: 10.1038/s41564-019-0387-8

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  195. Frequent intragenic microdeletions of elastin in familial supravalvular aortic stenosis

    Hayano Satoshi, Okuno Yusuke, Tsutsumi Makiko, Inagaki Hidehito, Fukasawa Yoshie, Kurahashi Hiroki, Kojima Seiji, Takahashi Yoshiyuki, Kato Taichi

    INTERNATIONAL JOURNAL OF CARDIOLOGY   Vol. 274   page: 290 - 295   2019.1

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    DOI: 10.1016/j.ijcard.2018.09.032

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  196. Ureteral dilatation detected in magnetic resonance imaging predicts vesicoureteral reflux in children with urinary tract infection

    Murakami Norihiro, Kawada Jun-ichi, Watanabe Azumi, Arakawa Toshinao, Kano Takamasa, Suzuki Takako, Tanaka Ryo, Kojima Daiei, Kawano Yoshihiko, Hoshino Shin, Muramatsu Hideki, Takahashi Yoshiyuki, Sato Yoshiaki, Koyama Masashi, Natsume Jun

    PLOS ONE   Vol. 13 ( 12 ) page: e0209595   2018.12

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    DOI: 10.1371/journal.pone.0209595

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  197. Identification of potential pathogenic viruses in patients with acute myocarditis using next-generation sequencing

    Takeuchi Suguru, Kawada Jun-ichi, Okuno Yusuke, Horiba Kazuhiro, Suzuki Takako, Torii Yuka, Yasuda Kazushi, Numaguchi Atsushi, Kato Taichi, Takahashi Yoshiyuki, Ito Yoshinori

    JOURNAL OF MEDICAL VIROLOGY   Vol. 90 ( 12 ) page: 1814 - 1821   2018.12

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    DOI: 10.1002/jmv.25263

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  198. Reduction of stratum corneum ceramides in Neu-Laxova syndrome caused by phosphoglycerate dehydrogenase deficiency

    Takeichi Takuya, Okuno Yusuke, Kawamoto Akane, Inoue Takeshi, Nagamoto Eiko, Murase Chiaki, Shimizu Eri, Tanaka Kenichi, Kageshita Yuichi, Fukushima Satoshi, Kono Michihiro, Ishikawa Junko, Ihn Hironobu, Takahashi Yoshiyuki, Akiyama Masashi

    JOURNAL OF LIPID RESEARCH   Vol. 59 ( 12 ) page: 2413 - 2420   2018.12

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    DOI: 10.1194/jlr.P087536

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  199. The presence of defective Epstein-Barr virus (EBV) infection in EBV-associated hematological malignancies

    Okuno Yusuke, Murata Takayuki, Sato Yoshitaka, Ito Yoshinori, Yoshida Kenichi, Sawada Akihisa, Shiraishi Yuichi, Miyano Satoru, Takahashi Yoshiyuki, Kojima Seiji, Ogawa Seishi, Kimura Hiroshi

    CANCER SCIENCE   Vol. 109   page: 642 - 642   2018.12

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  200. Clinical and Genetic Characteristics of Patients with Shwachman-Diamond Syndrome in Japan

    Watanabe Kenichiro, Kanegane Hirokazu, Hamabata Takayuki, Kozuki Kagehiro, Umeda Katsutsugu, Ueno Hiroo, Yoshida Kenichi, Hama Asahito, Okuno Yusuke, Muramatsu Hideki, Takahashi Yoshiyuki, Hasegawa Daisuke, Manabe Atsushi, Ohara Akira, Ito Masafumi, Ogawa Seishi, Kojima Seiji, Ito Etsuro

    BLOOD   Vol. 132   2018.11

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    DOI: 10.1182/blood-2018-99-114313

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  201. Combination of TREC Measurement and Next-Generation Sequencing in Newborn Screening for Severe Combined Immunodeficiency: A Pilot Program in Japan

    Muramatsu Hideki, Kojima Daiei, Okuno Yusuke, Kataoka Shinsuke, Nakajima Yoko, Ito Tetsuya, Tsuge Ikuya, Yoshimi Sakai, Kato Tomoaki, Kojima Seiji, Takahashi Yoshiyuki

    BLOOD   Vol. 132   2018.11

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    DOI: 10.1182/blood-2018-99-118261

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  202. <i>Piggybac</i> CD19 CAR T Cells Eradicate CNS Leukemia By Direct Delivery into Cerebral Ventricle of Xenograft Mice Model

    Tanaka Kuniaki, Kato Itaru, Tanaka Miyuki, Morita Daisuke, Takahashi Yoshiyuki, Nakahata Tatsutoshi, Umeda Katsutsugu, Hiramatsu Hidefumi, Adachi Souichi, Takita Junko, Nakazawa Yozo

    BLOOD   Vol. 132   2018.11

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    DOI: 10.1182/blood-2018-99-111733

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  203. Randomized Trial of Two Dosages of Rabbit Antithymocyte Globulin in Patients with Aplastic Anemia

    Narita Atsushi, Zhu Xiaofan, Muramatsu Hideki, Chen Xiaojuan, Guo Ye, Yang Wenyu, Zhang Jingliao, Liu Fang, Jang Jun Ho, Kook Hoon, Kim Hawk, Usuki Kensuke, Yamazaki Hirohito, Takahashi Yoshiyuki, Nakao Shinji, Lee Jong-Wook, Kojima Seiji

    BLOOD   Vol. 132   2018.11

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    DOI: 10.1182/blood-2018-99-111323

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  204. The Presence of Defective Epstein-Barr Virus (EBV) Infection in Patients with EBV-Associated Hematological Malignancy

    Okuno Yusuke, Murata Takayuki, Sato Yoshitaka, Muramatsu Hideki, Ito Yoshinori, Watanabe Takahiro, Okuno Tatsuya, Murakami Norihiro, Yoshida Kenichi, Sawada Akihisa, Inoue Masami, Kawa Keisei, Seto Masao, Ohshima Koichi, Shiraishi Yuichi, Chiba Kenichi, Tanaka Hiroko, Miyano Satoru, Narita Yohei, Yoshida Masahiro, Goshima Fumi, Kawada Junichi, Nishida Tetsuya, Kiyoi Hitoshi, Kato Seiichi, Nakamura Shigeo, Morishima Satoko, Fujiwara Shigeyoshi, Shimizu Norio, Isobe Yasushi, Noguchi Masaaki, Kikuta Atsushi, Iwatsuki Keiji, Takahashi Yoshiyuki, Kojima Seiji, Ogawa Seishi, Kimura Hiroshi

    BLOOD   Vol. 132   2018.11

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    DOI: 10.1182/blood-2018-99-113801

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  205. Application of RNA Sequencing for Early Diagnosis of NUT Carcinoma: A Case Report

    Miwata Shunsuke, Narita Atsushi, Wakamatsu Manabu, Narita Kotaro, Kitazawa Hironobu, Kataoka Shinsuke, Hamada Motoharu, Murakami Norihiro, Taniguchi Rieko, Ichikawa Daisuke, Suzuki Kyogo, Kawashima Nozomu, Nishikawa Eri, Okuno Yusuke, Nishio Nobuhiro, Muramatsu Hideki, Kojima Seiji, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 65   page: S74-S74   2018.11

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  206. A Case of Thoracic Tumor Caused by SMARCA4 Biallelic Inactivation

    Ichikawa Daisuke, Muramatsu Hideki, Okuno Yusuke, Wakamatsu Manabu, Miwata Shunsuke, Narita Kotaro, Kitazawa Hironobu, Hamada Motoharu, Kataoka Shinsuke, Taniguchi Rieko, Murakami Norihiro, Suzuki Kyogo, Nishikawa Eri, Kawashima Nozomu, Narita Atsushi, Nishio Nobuhiro, Kojima Seiji, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 65   page: S74-S74   2018.11

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  207. A Case of MLL-AF9 Fusion Positive Malignant Lymphoma Without Bone Marrow Infiltration Either at First Diagnosis or at Relapse

    Narita Kotaro, Kataoka Shinsuke, Hamada Motoharu, Ichikawa Daisuke, Taniguchi Rieko, Murakami Norihiro, Suzuki Kyogo, Nishikawa Eri, Nishio Nobuhiro, Okuno Yusuke, Kawashima Nozomu, Narita Atsushi, Muramatsu Hideki, Kojima Seiji, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 65   page: S99-S99   2018.11

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  208. A Case of Dyskeratosis Congenital who Showed the Improvement of Telomere Length After Receiving Androgens for 11 Years

    Wakamatsu Manabu, Nishio Nobuhiro, Miwata Shunsuke, Narita Kotaro, Kitazawa Hironobu, Kataoka Shinsuke, Hamada Motoharu, Murakami Norihiro, Ichikawa Daisuke, Taniguchi Rieko, Suzuki Kyogo, Kawashima Nozomu, Nishikawa Eri, Okuno Yusuke, Narita Atsushi, Muramatsu Hideki, Kojima Seiji, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 65   page: S65-S65   2018.11

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  209. Diagnosis of Inherited Bone Marrow Failure Syndromes Using Sequencing Approaches

    Narita Atsushi, Muramatsu Hideki, Okuno Yusuke, Yoshida Kenichi, Shiraishi Yuichi, Sakaguchi Hirotoshi, Kawashima Nozomu, Wang Xinan, Xu Yinyan, Chiba Kenichi, Tanaka Hiroko, Hama Asahito, Sanada Masashi, Hitoshi Kanno, Yamaguchi Hiroki, Ohga Shouichi, Manabe Atsushi, Harigae Hideo, Kunishima Shinji, Ishii Eiichi, Kobayashi Masao, Koike Kenichi, Watanabe Kenichiro, Ito Etsuro, Takata Minoru, Yabe Miharu, Ogawa Seishi, Miyano Satoru, Kojima Seiji, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 65   page: S7 - S7   2018.11

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  210. Disappearance of Minimal Residual Disease Demonstrates Graft Versus Neuroblastoma Effect After KIR-Ligand Mismatched Allogeneic Cord Blood Transplantation

    Nishio Nobuhiro, Kataoka Shinsuke, Miwata Shunsuke, Narita Kotaro, Kitazawa Hironobu, Hamada Motoharu, Ichikawa Daisuke, Taniguchi Rieko, Murakami Norihiro, Suzuki Kyogo, Kawashima Nozomu, Nishikawa Eri, Okuno Yusuke, Narita Atsushi, Muramatsu Hideki, Kojima Seiji, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 65   page: S8 - S8   2018.11

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  211. Herpesvirus Infection in Pediatric Autologous Hematopoietic Stem Cell Transplantation

    Miura Hiroki, Kudo Kazuko, Tanaka Makito, Takahashi Yoshiyuki, Kojima Seiji, Yoshikawa Tetsushi

    PEDIATRIC BLOOD & CANCER   Vol. 65   page: S60 - S61   2018.11

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  212. Unmet Medical Needs for Japanese Kampo Medicine in Children with Hematological and Oncological Disease

    Kawashima Nozomu, Miwata Shunsuke, Narita Kotaro, Kataoka Shinsuke, Hamada Motoharu, Murakami Norihiro, Ichikawa Daisuke, Suzuki Kyogo, Kitazawa Hironobu, Nishikawa Eri, Okuno Yusuke, Taniguchi Rieko, Narita Atsushi, Muramatsu Hideki, Nishio Nobuhiro, Kojima Seiji, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 65   page: S33 - S33   2018.11

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  213. Urgent Successful HLA-Haploidentical Stem Cell Transplantation in Children with Aplastic Anemia Considering Upfront SCT Strategy

    Nishikawa Eri, Wakamatsu Manabu, Miwata Shunsuke, Narita Kotaro, Murakami Norihiro, Kataoka Shinsuke, Hamada Motoharu, Ichikawa Daisuke, Kitazawa Hironobu, Taniguchi Rieko, Suzuki Kyogo, Kawashima Nozomu, Okuno Yusuke, Narita Atsushi, Muramatsu Hideki, Nishio Nobuhiro, Kojima Seiji, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 65   page: S65 - S66   2018.11

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  214. Morphological Features of Bone Marrow in Patients with Inherited Bone Marrow Failure

    Hama Asahito, Hasegawa Daisuke, Manabe Atsushi, Nozawa Kazue, Narita Atsushi, Okuno Yusuke, Muramatsu Hideki, Takahashi Yoshiyuki, Watanabe Kenichiro, Ohara Akira, Ito Masafumi, Kojima Seiji

    PEDIATRIC BLOOD & CANCER   Vol. 65   page: S66 - S66   2018.11

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  215. NGS-Based Methylation Analysis of Juvenile Myelomonocytic Leukemia using the Digital Restriction Enzyme Analysis of Methylation (DREAM) Method

    Kitazawa Hironobu, Murakami Norihiro, Okuno Yusuke, Muramatsu Hideki, Wakamatsu Manabu, Miwata Shunsuke, Narita Kotaro, Kataoka Shinsuke, Hamada Motoharu, Ichikawa Daisuke, Taniguchi Rieko, Suzuki Kyogo, Kawashima Nozomu, Nishikawa Eri, Narita Atsushi, Nishio Nobuhiro, Kojima Seiji, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 65   page: S22 - S23   2018.11

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  216. Relapse After Spontaneous Molecular Remission in a Female with Congenital Acute Myeloid Leukemia with KAT6A-EP300 Fusion Transcript

    Taniguchi Rieko, Kawashima Nozomu, Ikawa Yasuhiro, Wakamatsu Manabu, Miwata Shunsuke, Narita Kotaro, Kataoka Shinsuke, Hamada Motoharu, Murakami Norihiro, Ichikawa Daisuke, Kitazawa Hironobu, Suzuki Kyogo, Nishikawa Eri, Narita Atsushi, Okuno Yusuke, Muramatsu Hideki, Nishio Nobuhiro, Nishimura Ryosei, Kojima Seiji, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 65   page: S98 - S98   2018.11

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  217. Defibrotide for Prophylaxis of Hepatic Veno-Occlusive Disease Hematopoietic Stem Cell Transplantation: Results from the Japanese Prophylactic Use, Phase II, Randomized Trial

    Kikuta Atsushi, Fukuda Takahiro, Ohashi Kazuteru, Taniguchi Shuichi, Asano-Mori Yuki, Horibe Keizo, Goto Hiroaki, Nakamae Hirohisa, Ogawa Hiroyasu, Tamaki Hiroya, Takahashi Yoshiyuki, Kimura Toshimi, Yoshimura Kenichi, Umemura Kazuo, Ogawa Chitose

    BONE MARROW TRANSPLANTATION   Vol. 53   page: 316 - 317   2018.9

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  218. Defibrotide for Treatment of Hepatic Veno-Occlusive Disease Following Hematopoietic Stem Cell Transplantation: Results from the Japanese Therapeutic Use Protocol

    Kikuta Atsushi, Fukuda Takahiro, Ohashi Kazuteru, Taniguchi Shuichi, Asano-Mori Yuki, Horibe Keizo, Goto Hiroaki, Nakamae Hirohisa, Ogawa Hiroyasu, Tamaki Hiroya, Takahashi Yoshiyuki, Kimura Toshimi, Yoshimura Kenichi, Umemura Kazuo, Ogawa Chitose

    BONE MARROW TRANSPLANTATION   Vol. 53   page: 318 - 319   2018.9

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  219. Updated Treatment Algorism for Children with Acquired Aplastic Anemia: A Report from the Japan Childhood Aplastic Anemia Study Group

    Yoshida Nao, Narita Atsushi, Muramatsu Hideki, Kobayashi Ryoji, Yabe Hiromasa, Kudo Kazuko, Yagasaki Hiroshi, Watanabe Kenichiro, Morimoto Akira, Ito Etsuro, Ohga Shouichi, Ohara Akira, Takahashi Yoshiyuki, Kojima Seiji

    BONE MARROW TRANSPLANTATION   Vol. 53   page: 34 - 35   2018.9

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  220. Whole-exome analysis to detect congenital hemolytic anemia mimicking congenital dyserythropoietic anemia

    Hamada Motoharu, Doisaki Sayoko, Okuno Yusuke, Muramatsu Hideki, Hama Asahito, Kawashima Nozomu, Narita Atsushi, Nishio Nobuhiro, Yoshida Kenichi, Kanno Hitoshi, Manabe Atsushi, Taga Takashi, Takahashi Yoshiyuki, Miyano Satoru, Ogawa Seishi, Kojima Seiji

    INTERNATIONAL JOURNAL OF HEMATOLOGY   Vol. 108 ( 3 ) page: 306 - 311   2018.9

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    DOI: 10.1007/s12185-018-2482-7

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  221. Risk Factors for Viral Infections in Pediatric Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

    Narita Atsushi, Ito Yoshinori, Torii Yuka, Kawada Jun-Ichi, Miwata Shunsuke, Narita Kotaro, Kitazawa Hironobu, Hamada Motoharu, Kataoka Shinsuke, Ichikawa Daisuke, Ito Rieko, Murakami Norihiro, Kojima Daiei, Suzuki Kyogo, Nishikawa Eri, Kawashima Nozomu, Okuno Yusuke, Muramatsu Hideki, Hama Asahito, Kojima Seiji, Takahashi Yoshiyuki

    BONE MARROW TRANSPLANTATION   Vol. 53   page: 588 - 589   2018.9

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  222. Integration Mapping of <i>piggyBac</i>-Mediated CD19 Chimeric Antigen Receptor T Cells Analyzed by Novel Tagmentation-Assisted PCR

    Hamada Motoharu, Nishio Nobuhiro, Okuno Yusuke, Suzuki Satoshi, Kawashima Nozomu, Muramatsu Hideki, Tsubota Shoma, Wilson Matthew H., Morita Daisuke, Kataoka Shinsuke, Ichikawa Daisuke, Murakami Norihiro, Taniguchi Rieko, Suzuki Kyogo, Kojima Daiei, Sekiya Yuko, Nishikawa Eri, Narita Atsushi, Hama Asahito, Kojima Seiji, Nakazawa Yozo, Takahashi Yoshiyuki

    EBIOMEDICINE   Vol. 34   page: 18 - 26   2018.8

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    DOI: 10.1016/j.ebiom.2018.07.008

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  223. Late-phase human herpesvirus 6B reactivation in hematopoietic stem cell transplant recipients

    Miura Hiroki, Kawamura Yoshiki, Hattori Fumihiko, Tanaka Makito, Kudo Kazuko, Ihira Masaru, Yatsuya Hiroshi, Takahashi Yoshiyuki, Kojima Seiji, Yoshikawa Tetsushi

    TRANSPLANT INFECTIOUS DISEASE   Vol. 20 ( 4 ) page: e12916   2018.8

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    DOI: 10.1111/tid.12916

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  224. Diagnostic performance of <SUP>18</SUP>F-FDG PET/CT and whole-body diffusion-weighted imaging with background body suppression (DWIBS) in detection of lymph node and bone metastases from pediatric neuroblastoma

    Ishiguchi Hiroaki, Ito Shinji, Kato Katsuhiko, Sakurai Yusuke, Kawai Hisashi, Fujita Naotoshi, Abe Shinji, Narita Atsushi, Nishio Nobuhiro, Muramatsu Hideki, Takahashi Yoshiyuki, Naganawa Shinji

    ANNALS OF NUCLEAR MEDICINE   Vol. 32 ( 5 ) page: 348 - 362   2018.6

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    DOI: 10.1007/s12149-018-1254-z

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  225. Integrated molecular profiling of juvenile myelomonocytic leukemia

    Murakami Norihiro, Okuno Yusuke, Yoshida Kenichi, Shiraishi Yuichi, Nagae Genta, Suzuki Kyogo, Narita Atsushi, Sakaguchi Hirotoshi, Kawashima Nozomu, Wang Xinan, Xu Yinyan, Chiba Kenichi, Tanaka Hiroko, Hama Asahito, Sanada Masashi, Ito Masafumi, Hirayama Masashi, Watanabe Arata, Ueno Toshihide, Kojima Seiji, Aburatani Hiroyuki, Mano Hiroyuki, Miyano Satoru, Ogawa Seishi, Takahashi Yoshiyuki, Muramatsu Hideki

    BLOOD   Vol. 131 ( 14 ) page: 1576 - 1586   2018.4

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    DOI: 10.1182/blood-2017-07-798157

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  226. Phase I study of cord blood transplantation with intrabone marrow injection of mesenchymal stem cells: A clinical study protocol

    Goto Tatsunori, Murata Makoto, Terakura Seitaro, Nishida Tetsuya, Adachi Yoshiya, Ushijima Yoko, Shimada Kazuyuki, Ishikawa Yuichi, Hayakawa Fumihiko, Nishio Nobuhiro, Nishiwaki Satoshi, Hirakawa Akihiro, Kato Katsuyoshi, Takahashi Yoshiyuki, Kiyoi Hitoshi

    MEDICINE   Vol. 97 ( 17 ) page: e0449   2018.4

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    DOI: 10.1097/MD.0000000000010449

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  227. Enhanced Expression of Anti-CD19 Chimeric Antigen Receptor in <i>piggyBac</i> Transposon-Engineered T Cells

    Morita Daisuke, Nishio Nobuhiro, Saito Shoji, Tanaka Miyuki, Kawashima Nozomu, Okuno Yusuke, Suzuki Satoshi, Matsuda Kazuyuki, Maeda Yasuhiro, Wilson Matthew H., Dotti Gianpietro, Rooney Cliona M., Takahashi Yoshiyuki, Nakazawa Yozo

    MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT   Vol. 8   page: 131 - 140   2018.3

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    DOI: 10.1016/j.omtm.2017.12.003

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  228. Comprehensive detection of pathogens in immunocompromised children with bloodstream infections by next-generation sequencing

    Horiba Kazuhiro, Kawada Jun-ichi, Okuno Yusuke, Tetsuka Nobuyuki, Suzuki Takako, Ando Shotaro, Kamiya Yasuko, Torii Yuka, Yagi Tetsuya, Takahashi Yoshiyuki, Ito Yoshinori

    SCIENTIFIC REPORTS   Vol. 8 ( 1 ) page: 3784   2018.2

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    DOI: 10.1038/s41598-018-22133-y

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  229. Comprehensive genetic analysis of donor cell derived leukemia with KMT2A rearrangement

    Taniguchi Rieko, Muramatsu Hideki, Okuno Yusuke, Suzuki Kyogo, Obu Satoshi, Nakatochi Masahiro, Shimamura Teppei, Takahashi Yoshiyuki, Horikoshi Yasuo, Watanabe Kenichiro, Kojima Seiji

    PEDIATRIC BLOOD & CANCER   Vol. 65 ( 2 )   2018.2

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    DOI: 10.1002/pbc.26823

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  230. Neurocan, an extracellular chondroitin sulfate proteoglycan, stimulates neuroblastoma cells to promote malignant phenotypes

    Su Zhendong, Kishida Satoshi, Tsubota Shoma, Sakamoto Kazuma, Cao Dongliang, Kiyonari Shinichi, Ohira Miki, Kamijo Takehiko, Narita Atsushi, Xu Yinyan, Takahashi Yoshiyuki, Kadomatsu Kenji

    ONCOTARGET   Vol. 8 ( 63 ) page: 106296 - 106310   2017.12

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    DOI: 10.18632/oncotarget.22435

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  231. Clinical Trial of CD19 CAR-T Cell Therapy with non-virus Vector System

    Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 64   page: S3-S3   2017.11

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  232. Bevacizumab, Irinotecan, and Temozolomide Combination as Salvage Chemotherapy for Relapsed Pediatric Brain Tumor

    Kataoka Shinsuke, Muramatsu Hideki, Narita Kotaro, Hamada Motoharu, Murakami Norihiro, Tanigushi Rieko, Ichikawa Daisuke, Kitazawa Hironori, Kojima Daiei, Suzuki Kyogo, Kawashima Nozomu, Nishikawa Eri, Narita Atsushi, Okuno Yusuke, Nishio Nobuhiro, Hama Asahito, Kojima Seiji, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 64   page: S55-S55   2017.11

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  233. Comprehensive detection of viruses in pediatric patients with acute liver failure using next-generation sequencing

    Suzuki Takako, Kawada Jun-ichi, Okuno Yusuke, Hayano Satoshi, Horiba Kazuhiro, Torii Yuka, Takahashi Yoshiyuki, Umetsu Syuichiro, Sogo Tsuyoshi, Inui Ayano, Ito Yoshinori

    JOURNAL OF CLINICAL VIROLOGY   Vol. 96   page: 67 - 72   2017.11

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    DOI: 10.1016/j.jcv.2017.10.001

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  234. Clinical Prognostic Factors in Patients with High-risk Neuroblastoma Undergoing A Single Autologous Stem Cell Transplant

    Saito Yuya, Kiyotani Chikako, Inoue Masami, Takahashi Yoshiyuki, Ogawa Atsushi, Chin Motoaki, Koga Yuuki, Kato Koji, Koh Katsuyoshi, Watanabe Kenichiro, Hashii Yoshiko, Sato Atsushi, Atsuta Yuko, Matsumoto Kimikazu

    PEDIATRIC BLOOD & CANCER   Vol. 64   page: S42 - S42   2017.11

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  235. Human Herpesvirus 6B Infection in Pediatric Hematopoietic Stem Cell Transplantation

    Miura Hiroki, Kudo Kazuko, Tanaka Makito, Takahashi Yoshiyuki, Kojima Seji, Kato Koji, Yoshida Nao, Sakaguchi Hirotoshi, Yoshikawa Tetsushi

    PEDIATRIC BLOOD & CANCER   Vol. 64   page: S76 - S76   2017.11

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  236. Killer Cell Immunoglobulin-like Receptor Ligand-mismatched Allogeneic Cord Blood Transplantation Reduces Relapse and Improves Survival in Children with Refractory Neuroblastoma

    Nishio Nobuhiro, Kataoka Shinnsuke, Hamada Motoharu, Ichikawa Daisuke, Taniguchi Rieko, Murakami Norihiro, Kojima Daiei, Suzuki Kyogo, Kawasima Nozomu, Nishikawa Eri, Okuno Yusuke, Narita Atsushi, Muramatsu Hideki, Hama Asahito, Kojima Seiji, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 64   page: S23 - S24   2017.11

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  237. Integrated Molecular Profiling of Juvenile Myelomonocytic Leukemia

    Murakami Norihiro, Muramatsu Hideki, Okuno Yusuke, Yoshida Kenichi, Shiraishi Yuichi, Nagae Genta, Suzuki Kyogo, Narita Atsushi, Sakaguchi Hirotoshi, Kawashima Nozomu, Wang Xinan, Xu Yinyan, Chiba Kenichi, Tanaka Hiroko, Nishio Nobuhiro, Hama Asahito, Sanada Masashi, Hirayama Masashi, Watanabe Arata, Ueno Toshihide, Kojima Seiji, Aburatani Hiroyuki, Mano Hiroyuki, Miyano Satoru, Ogawa Seishi, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 64   page: S19 - S20   2017.11

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  238. Identification of FLVCR1 as a Novel Causative Gene of Inherited Ineffective Erythropoiesis in Humans

    Kawashima Nozomu, Okuno Yusuke, Shiota Mitsutaka, Muramatsu Hideki, Yoshida Kenichi, Ikawa Masahito, Hama Asahito, Ito Masafumi, Doisaki Sayoko, Murakami Norihiro, Suzuki Kyogo, Narita Atsushi, Nishio Nobuhiro, Takahashi Yoshiyuki, Ogawa Seishi, Kojima Seiji

    PEDIATRIC BLOOD & CANCER   Vol. 64   page: S20 - S20   2017.11

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  239. Correlation of Bone Marrow Morphology with Clinical Findings and Gene Alterations in Patients with Diamond-Blackfan Anemia

    Hama Asahito, Toki Tsutomu, Kobayashi Akie, Muramatsu Hideki, Okuno Yusuke, Hasegawa Daisuke, Nozawa Kazue, Takahashi Yoshiyuki, Watanabe Kenichiro, Manabe Atsushi, Ito Masafumi, Ito Etsuro, Kojima Seiji

    PEDIATRIC BLOOD & CANCER   Vol. 64   page: S28 - S28   2017.11

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  240. Germline Mutation in Pediatric Patients with Aplastic Anemia

    Narita Atsushi, Muramatsu Hideki, Okuno Yusuke, Wang Xinan, Xu Yinyan, Kawashima Nozomu, Nishio Nobuhiro, Hama Asahito, Sakaguchi Hirotoshi, Yoshida Nao, Kato Koji, Kojima Seiji, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 64   page: S28 - S29   2017.11

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  241. Vorinostat and Bortezomib Combined Intensive Chemotherapy for Children with <i>KMT2A</i> (<i>MLL</i>)-rearranged Acute Lymphoblastic Leukemia

    Suzuki Kyogo, Muramatsu Hideki, Okuno Yusuke, Narita Kotaro, Kitazawa Hironobu, Huang Yue, Ichikawa Daisuke, Kataoka Shinsuke, Hamada Motoharu, Murakami Norihiro, Taniguchi Rieko, Kojima Daiei, Sekiya Yuko, Nishikawa Eri, Kawashima Nozomu, Narita Atsushi, Nishio Nobuhiro, Hama Asahito, Kojima Seiji, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 64   page: S90 - S90   2017.11

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  242. Newborn Screening for Severe Combined Immunodeficiency in Aichi Prefecture

    Kojima Daiei, Muramatsu Hideki, Okuno Yusuke, Narita Kotaro, Murakami Norihiro, Ichikawa Daisuke, Hamada Motoharu, Kataoka Shinsuke, Kitazawa Hironobu, Taniguchi Rieko, Suzuki Kyogo, Kawashima Nozomu, Nishikawa Eri, Narita Atsushi, Nishio Nobuhiro, Hama Asahito, Kojima Seiji, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 64   page: S33 - S33   2017.11

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  243. Retrospective Analysis of High Risk Childhood AML Undergoing Allo-SCT in First CR: Results of AML-05 by JPLSG

    Hyakuna Nobuyuki, Hashii Yoshiko, Ishida Hiroyuki, Umeda Katsutsugu, Takahashi Yoshiyuki, Nagasawa Masayuki, Yabe Hiromasa, Nakazawa Yozo, Koh Katsuyoshi, Goto Hiroaki, Fujisaki Hiroyuki, Matsumoto Kimikazu, Kakuda Harumi, Yano Michihiro, Tawa Akio, Tomizawa Daisuke, Taga Takashi, Adachi Souichi, Kato Koji

    PEDIATRIC BLOOD & CANCER   Vol. 64   page: S68 - S68   2017.11

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  244. Treatment Outcomes and Prognostic Factors after Allogeneic-HSCT for Patients with Low and Intermediate Risk in JPLSG AML-05 study

    Hashii Yoshiko, Hyakuna Nobuyuki, Ishida Hiroyuki, Umeda Katsutsugu, Takahashi Yoshiyuki, Nagasawa Masayuki, Yabe Hiromasa, Nakazawa Yozo, Fujisaki Hiroyuki, Yano Michihiro, Matsumoto Kimikazu, Goto Hiroaki, Kakuda Harumi, Koh Katsuyoshi, Tomizawa Daisuke, Tawa Akio, Taga Takashi, Adachi Souichi, Kato Koji

    PEDIATRIC BLOOD & CANCER   Vol. 64   page: S19 - S19   2017.11

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  245. Successful Allogeneic Cord Blood Transplantation in three Children with Aplastic Anemia Pretreated with Flu plus Mel plus TBI

    Nishikawa Eri, Kitazawa Hironobu, Narita Koutarou, Hamada Motoharu, Kataoka Shinsuke, Murakami Norihiro, Ichikawa Daisuke, Kojima Daiei, Suzuki Kyogo, Taniguchi Rieko, Kawashima Nozomu, Narita Atsushi, Okuno Yusuke, Muramatsu Hideki, Nishio Nobuhiro, Hama Asahito, Kojima Seiji, Takahashi Yoshiyuki

    PEDIATRIC BLOOD & CANCER   Vol. 64   page: S75 - S76   2017.11

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  246. Development of clinical paroxysmal nocturnal haemoglobinuria in children with aplastic anaemia

    Narita Atsushi, Muramatsu Hideki, Okuno Yusuke, Sekiya Yuko, Suzuki Kyogo, Hamada Motoharu, Kataoka Shinsuke, Ichikawa Daisuke, Taniguchi Rieko, Murakami Norihiro, Kojima Daiei, Nishikawa Eri, Kawashima Nozomu, Nishio Nobuhiro, Hama Asahito, Takahashi Yoshiyuki, Kojima Seiji

    BRITISH JOURNAL OF HAEMATOLOGY   Vol. 178 ( 6 ) page: 954 - 958   2017.9

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    DOI: 10.1111/bjh.14790

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  247. Bone marrow transplantation for children with acquired bone marrow failure

    Hama A., Manabe A., Hasegawa D., Nozawa K., Suzuki K., Narita A., Muramatsu H., Takahashi Y., Watanabe K., Ohara A., Ito M., Kojima S.

    BONE MARROW TRANSPLANTATION   Vol. 52   page: S414-S414   2017.7

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  248. Clinical utility of next-generation sequencing for inherited bone marrow failure syndromes

    Muramatsu Hideki, Okuno Yusuke, Yoshida Kenichi, Shiraishi Yuichi, Doisaki Sayoko, Narita Atsushi, Sakaguchi Hirotoshi, Kawashima Nozomu, Wang Xinan, Xu Yinyan, Chiba Kenichi, Tanaka Hiroko, Hama Asahito, Sanada Masashi, Takahashi Yoshiyuki, Kanno Hitoshi, Yamaguchi Hiroki, Ohga Shouichi, Manabe Atsushi, Harigae Hideo, Kunishima Shinji, Ishii Eiichi, Kobayashi Masao, Koike Kenichi, Watanabe Kenichiro, Ito Etsuro, Takata Minoru, Yabe Miharu, Ogawa Seishi, Miyano Satoru, Kojima Seiji

    GENETICS IN MEDICINE   Vol. 19 ( 7 ) page: 796-802   2017.7

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    DOI: 10.1038/gim.2016.197

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  249. PiggyBac transposon, a non-viral gene transfer system, mediated T cells expressing CD19 chimeric antigen receptor for a 'first in human' clinical trial

    Takahashi Y., Nishio N., Hamada M., Tanaka M., Morita D., Kawashima N., Okuno Y., Narita A., Muramatsu H., Hama A., Kojima S., Dotti G., Nakazawa Y.

    BONE MARROW TRANSPLANTATION   Vol. 52   page: S161 - S162   2017.7

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  250. Recurrent <i>MYB</i> rearrangement in blastic plasmacytoid dendritic cell neoplasm

    Suzuki K., Suzuki Y., Hama A., Muramatsu H., Nakatochi M., Gunji M., Ichikawa D., Hamada M., Taniguchi R., Kataoka S., Murakami N., Kojima D., Sekiya Y., Nishikawa E., Kawashima N., Narita A., Nishio N., Nakazawa Y., Iwafuchi H., Watanabe K-i, Takahashi Y., Ito M., Kojima S., Kato S., Okuno Y.

    LEUKEMIA   Vol. 31 ( 7 ) page: 1629 - 1633   2017.7

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    DOI: 10.1038/leu.2017.101

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  251. RECURRENT MYB REARRANGEMENT IN BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM

    Suzuki K., Okuno Y., Suzuki Y., Hama A., Muramatsu H., Nakatochi M., Gunji M., Ichikawa D., Hamada M., Taniguchi R., Kataoka S., Murakami N., Kojima D., Sekiya Y., Nishikawa E., Kawashima N., Narita A., Nishio N., Nakazawa Y., Iwafuchi H., Watanabe K., Ito M., Kojima S., Kato S., Takahashi Y.

    HAEMATOLOGICA   Vol. 102   page: 35 - 35   2017.6

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  252. Efficacy of neutrophil non-muscle myosin heavy chain-IIA immunofluorescence analysis in determining the pathogenicity of <i>MYH9</i> variants

    Kunishima Shinji, Yusuke Okuno, Muramatsu Hideki, Kojima Daiei, Nagai Noriko, Takahashi Yoshiyuki, Kojima Seiji

    ANNALS OF HEMATOLOGY   Vol. 96 ( 6 ) page: 1065 - 1066   2017.6

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    DOI: 10.1007/s00277-017-2972-3

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  253. Long-term outcomes of 95 children with moderate aplastic anemia treated with horse antithymocyte globulin and cyclosporine

    Nishikawa Eri, Yagasaki Hiroshi, Hama Asahito, Yabe Hiromasa, Ohara Akira, Kosaka Yoshiyuki, Kudo Kazuko, Kobayashi Ryoji, Ohga Shouichi, Morimoto Akira, Watanabe Ken-ichiro, Yoshida Nao, Muramatsu Hideki, Takahashi Yoshiyuki, Kojima Seiji

    PEDIATRIC BLOOD & CANCER   Vol. 64 ( 5 )   2017.5

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    DOI: 10.1002/pbc.26305

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  254. Paroxysmal nonepileptic events in children with epilepsy

    Ito Yuji, Kidokoro Hiroyuki, Negoro Tamiko, Tanaka Masaharu, Okai Yu, Sakaguchi Yoko, Ogawa Chikako, Takeuchi Tomoya, Ohno Atsuko, Yamamoto Hiroyuki, Nakata Tomohiko, Maesawa Satoshi, Watanabe Kazuyoshi, Takahashi Yoshiyuki, Natsume Jun

    EPILEPSY RESEARCH   Vol. 132   page: 59 - 63   2017.5

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    DOI: 10.1016/j.eplepsyres.2017.02.009

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  255. PiggyBac Mediated T Cells Expressing Anti CD19 Chimeric Antigen Receptor for a Clinical Trial

    Nishio Nobuhiro, Nakazawa Yozo, Hamada Motoharu, Suzuki Satoshi, Tanaka Miyuki, Morita Daisuke, Kawashima Nozomu, Okuno Yusuke, Narita Atsushi, Hama Asahito, Muramatsu Hideki, Muramatsu Hideki, Kojima Seiji, Takahashi Yoshiyuki

    MOLECULAR THERAPY   Vol. 25 ( 5 ) page: 291 - 291   2017.5

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  256. Germline IKAROS mutation associated with primary immunodeficiency that progressed to T-cell acute lymphoblastic leukemia

    Yoshida N., Sakaguchi H., Muramatsu H., Okuno Y., Song C., Dovat S., Shimada A., Ozeki M., Ohnishi H., Teramoto T., Fukao T., Kondo N., Takahashi Y., Matsumoto K., Kato K., Kojima S.

    LEUKEMIA   Vol. 31 ( 5 ) page: 1221 - 1223   2017.5

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    DOI: 10.1038/leu.2017.25

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  257. Investigation of a Rotavirus Gastroenteritis Outbreak among Immunosuppressed Patients in a Hospital Setting.

    Sugata K, Hull J, Wang H, Foytich K, Moon SS, Takahashi Y, Kojima S, Yoshikawa T, Jiang B

    Journal of immunological techniques in infectious diseases   Vol. 6 ( 1 )   2017.1

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    DOI: 10.4172/2329-9541.1000153

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  258. Clinical utility of next-generation sequencing-based minimal residual disease in paediatric B-cell acute lymphoblastic leukaemia

    Sekiya Yuko, Xu Yinyan, Muramatsu Hideki, Okuno Yusuke, Narita Atsushi, Suzuki Kyogo, Wang Xinan, Kawashima Nozomu, Sakaguchi Hirotoshi, Yoshida Nao, Hama Asahito, Takahashi Yoshiyuki, Kato Koji, Kojima Seiji

    BRITISH JOURNAL OF HAEMATOLOGY   Vol. 176 ( 2 ) page: 248-257   2017.1

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    DOI: 10.1111/bjh.14420

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  259. Allogeneic hematopoietic stem cell transplantation using ATG: prophylaxis and treatment.

    Nishio N, Takahashi Y, Kojima S

    [Rinsho ketsueki] The Japanese journal of clinical hematology   Vol. 58 ( 10 ) page: 2104 - 2110   2017

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    DOI: 10.11406/rinketsu.58.2104

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  260. *Relapse of leukemia with loss of mismatched HLA due to uniparental disomy following haploidentical hematopoietic stem cell transplantation. Reviewed

    Villalobos IB, Takahashi Y, Akatsuka Y, Muramatsu H, Nishio N, Hama A, Yagasaki H, Saji H, Kato M, Ogawa S, Kojima S.

    Blood   Vol. Epub ahead of print   page: Epub ahead of print   2010

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  261. *Regression of human kidney cancer following allogeneic stem cell transplantation is associated with recognition of an HERV-E antigen by T cells. Reviewed

    Takahashi, Y., N. Harashima, S. Kajigaya, H. Yokoyama, E. Cherkasova, J.P. McCoy, K.I. Hanada, O. Mena, R. Kurlander, T. Abdul, R. Srinivasan, A. Lundqvist, E. Malinzak, N. Geller, M.I. Lerman, and R.W. Childs.

    The Journal of Clinical Investigation   Vol. 118   page: 1099-1109.   2008

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  262. *In vitro and in vivo evidence of PNH cell sensitivity to immune attack after nonmyeloablative allogeneic hematopoietic cell transplantation. Reviewed

    Takahashi Y, McCoy JP Jr, Carvallo C, Rivera C, Igarashi T, Srinivasan R, Young NS, and Childs RW

    Blood   Vol. 103   page: 1383-1390   2004

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  263. *An Allogeneic-Based Immunotherapy For Renal Cell Carcinoma. Invited Reviewed

    Takahashi Y, Childs, R

    Clinical Cancer Research   Vol. 10 ( 18Pt2 ) page: 6353S-6359S   2004

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Books 1

  1. *Hematopoietic stem cell transplantation for solid tumors.

    Takahashi Y, Srinivasan R, and Childs R( Role: Joint author)

    Handbook of Stem Cells  2004 

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KAKENHI (Grants-in-Aid for Scientific Research) 9

  1. Improvement and Validation of a Discriminant Model for Amplification of the Neuroblastoma MYC Gene by Tyrosine Metabolite Markers

    Grant number:23K07308  2023.4 - 2026.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

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    Authorship:Coinvestigator(s) 

  2. CAR-T細胞機能を向上させるCAR構造の最適化

    Grant number:22K07298  2022.4 - 2025.3

    科学研究費助成事業  基盤研究(C)

    西尾 信博, 高橋 義行

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    CARの構造は1)抗原認識部位、2)スペーサー、3)共刺激分子、4)細胞内シグナル伝達ドメインにより成り立っている。共刺激分子の違いにより、サイトカイン産生能、増殖能、あるいは体内持続性が異なることが知られているが、共刺激分子以外の構成成分がCAR-T細胞の機能に与える影響は未だ不明である。本研究では、linker部分とspacer部分がCAR-T細胞の機能に与える影響を明らかにし、最適化することでより効果の高いCAR-T細胞を開発する。

  3. Investigating the pathogenesis of bone marrow failure in children using single-cell gene expression analysis.

    Grant number:22K07819  2022.4 - 2025.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

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  4. 横紋筋肉腫メタボローム解析(尿/組織)による診断マーカーとオンコメタボライト探索

    Grant number:22K07911  2022.4 - 2025.3

    科学研究費助成事業  基盤研究(C)

    住田 亙, 城田 千代栄, 成田 敦, 牧田 智, 田井中 貴久, 内田 広夫, 高橋 義行, 大澤 毅, 田中 裕次郎, 檜 顕成

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    小児の肉腫のなかで最も頻度が高い横紋筋肉腫を標的とし、その中心代謝に関与する代謝産物(オンコメタボライト)及びその特異的な代謝系を見出すことを目標に、生体内の情報を鋭敏且つ包括的に捉えやすいメタボロミクス(キャピラリー電気泳動質量分析法を中心に)に着目する。第一段階として、尿検体を研究サンプルとして用い、尿中代謝物解析(CE/MS:キャピラリー電気泳動質量分析法を中心にLC/MS: 液体クロマトグラフィー質量分析法)から、代謝物を網羅的に測定し、横紋筋肉腫の中心代謝に特異的な代謝物(オンコメタボライト)の解明を目指す。

  5. 腎芽腫メタボローム解析(尿/組織)による診断マーカーとオンコメタボライト探索

    Grant number:22K07276  2022.4 - 2025.3

    科学研究費助成事業  基盤研究(C)

    岡本 眞宗, 城田 千代栄, 成田 敦, 牧田 智, 田井中 貴久, 内田 広夫, 高橋 義行, 大澤 毅, 住田 亙, 田中 裕次郎, 檜 顕成

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    増殖・浸潤・転移などがんの進展における中心代謝と代謝リプログラミングの役割については未だ不明な点が多い。本研究で腎芽腫細胞に特異的な中心代謝に関与する代謝物(オンコメタボライト)を見出す。がん細胞に特異的な代謝系を見出すことにより、正常細胞の代謝系との違いを標的とする新たながんの治療戦略の開発を目指す。腎芽腫患児の尿、腫瘍組織のキャピラリー電気泳動質量分析法を中心とした代謝物解析により、中心代謝に関与するオンコメタボライトを探索し、従来の集学的治療と遺伝子解析だけでは解明できなかった病態解明及び新たな診断治療法の開発に繋げる。

  6. Development of a novel chimeric antigen receptor gene-modified T cell therapy targeting GD2 for neuroblastoma

    Grant number:19K08273  2019.4 - 2022.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

    Nishio Nobuhiro

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    In this study, in order to develop a new treatment for neuroblastoma, the most common solid tumor among pediatric cancers other than brain tumors, with fewer side effects, we generated a new chimeric antigen receptor CAR targeting GD2 expressed on the cell surface of neuroblastoma cells and used a piggyBac transposon gene transfer method with low production cost. CAR-T cell therapy for neuroblastoma. Multiple GD2.CAR-T cells could be generated by combining multiple antigen recognition sites and co-stimulatory molecules and optimizing the culture method. Functional analysis was performed, and it was possible to select GD2.CAR-T cells with potent tumor cell injury, low exhaustion, and good cell proliferation.

  7. Functional analysis of novel genes related to aplastic anemia using mouse models.

    Grant number:19K08297  2019.4 - 2022.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

    Atsushi Narita

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    We recurrently identified novel gene X mutations using whole exome analysis in children with aplastic anemia. We hypothesized that mutations in gene X might confer an advantage in myeloproliferation or immune escape in aplastic anemia patients. Using a mutant mouse model of gene X, we examined the functional significance of the novel gene X mutant allele in aplastic anemia. Bone marrow specimens were collected from gene X mutant mice and subjected to colony assay, expression analysis by RNA sequencing, MHC deletion analysis, and bone marrow competitive transplantation experiments. In all results, however, mutations in gene X showed no advantage over controls in myeloproliferation or immune escape.

  8. Molecular basis for KIR ligand-mismatched cord blood transplantation for advanced neuroblastoma

    Grant number:18H02690  2018.4 - 2021.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)

    Takahashi Yoshiyuki

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    Grant amount:\13650000 ( Direct Cost: \10500000 、 Indirect Cost:\3150000 )

    We were able to establish a Patient-derived Tumor Xenograft (PDX) model using tumors derived from neuroblastoma patients, and established PDX libraries in 5 cases from 18 neuroblastoma patients. Our established PDX model is used in the multicenter prospective clinical study (JN-H-20) nationwide.

  9. 小児難治性急性骨髄性白血病に対するアロ反応性NK細胞による抗腫瘍メカニズムの解明

    2008

    科学研究費補助金  基盤研究(C),課題番号:20591252

    高橋 義行

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