Updated on 2022/04/06
医学博士 （ 1999.9 名古屋大学 ）
liver transplantation
liver fialure
liver disease
Others / Others / Digestive Organs Internal Medicine
肝不全における病態肝移植後患者における病態肝疾患患者における病態
Nagoya University Faculty of Medicine
1985.4 - 1991.3
Country： Japan
日本内科学会
日本消化器病学会 学会評議員
日本肝臓学会 学会評議員
日本移植学会
日本再生医療学会
Frequent incidence of escape mutants after successful hepatitis B vaccine response and stopping of nucleos(t)ide analogues in liver transplant recipients. Reviewed
Ishigami M1, Honda T, Ishizu Y, Onishi Y, Kamei H, Hayashi K, Ogura Y, Hirooka Y, Goto H.
Liver Transpl Vol. 20 ( 10 ) page： 1211-1220 2014.10
Different effect of HBV vaccine after liver transplantation between chronic HBV carriers and non-HBV patients who received HBc-Ab positive grafts. Reviewed
Ishigami M, Kamei H, Nakamura T, Katano Y, Ando H, Kiuchi T, Goto H
J Gastroenterol Vol. 46 page： 367-377 2011.3
Change of strategies and future perspectives against hepatitis B recurrence after liver transplantation Invited Reviewed
Ishigami M, Ogura Y, Hirooka Y, Goto H.
World J Gastroenterol Vol. 21 ( 36 ) page： 10290-10298 2015.9
Anti-hepatitis B surface immunoglobulin reduction in early postoperative period after liver transplantation in hepatitis B virus-positive patients Reviewed
Ishigami M, Onishi Y, Ito T, Katano Y, Itoh A, Hirooka Y, Kiuchi T, Goto H.
Hepatol Res. Vol. 41 page： 1189-1198 2011.12
*Use of the Model for End-Stage Liver Disease (MELD) score to predict 1-year survival of Japanese patients with cirrhosis and to determine who will benefit from living donor liver transplantation.
Ishigami M, Honda T, Okumura A, Ishikawa T, Kobayashi M, Katano Y, Fujimoto Y, Kiuchi T, Goto H.
J Gastroenterol Vol. 43 page： 363-368 2008
Impact of recipient age and preoperative fasting blood glucose level as the risk factors of living donor liver transplantation in cirrhotic patients in the recent comprehensive era with knowledge of indications-recent status in a Japanese single center. Reviewed
Ishigami M, Onishi Y, Kamei H, Kiuchi T, Katano Y, Itoh A, Hirooka Y, Goto H
Hepatol Res Vol. 43 page： 1148-1155 2013.11
Long-term dynamics of hematological data and spleen volume in cirrhotic patients after liver transplantation-various dynamics depending on etiology. Reviewed
Ishigami M, Ishizu Y, Onishi Y, Kamei H, Kiuchi T, Itoh A, Hirooka Y, Katano Y, Goto H
Springerplus Vol. 2 page： 374 2013.8
Impact of early elevation of serum bilirubin during treatment with pegylated interferon and ribavirin in patients with chronic hepatitis C. Reviewed
Ishigami M, Hayashi K, Katano Y, Itoh A, Hirooka Y, Goto H.
Hepatol Res Vol. 40 page： 963-970 2010
Risk factors of recipient receving living donor liver transplantation in the comprehensive era of indication and perioperative managements. Reviewed
Ishigami M, Katano Y, Hayashi K, Ito A, Hirooka Y, Onishi Y, Nakamura T, Kiuchi T, Goto H.
Nagoya J Med Sci Vol. 72 page： 119-127 2010
*Two cases of central venous catheter-related thrombosis in living liver donors: how can the risk be minimized?
Vol. 23 page： 289-293 2009
*Mutations in carboxy-terminal part of E2 including PKR/eIF2 alpha phosphorylation homology domain and interferon sensitivity determining region of nonstructural 5A of hepatitis C virus 1b: Their correlation with response to interferon monotherapy and viral load.
Ukai K, Ishigami M, Yoshioka K, Kawabe N, Katano Y, Hayashi K, Honda T, Yano M, Goto H
World J Gastroenterol Vol. 23 page： 3722-3728 2006
Differences in the intestinal microbiome associated with diarrhea during lenvatinib treatment for hepatocellular carcinoma.
Inukai Y, Yamamoto K, Honda T, Ito T, Imai N, Ishizu Y, Nakamura M, Kawashima H, Ishigami M
Digestive diseases (Basel, Switzerland) 2022.3
Increased Risk of Thyroid Dysfunction by PD-1 and CTLA-4 Blockade in Patients Without Thyroid Autoantibodies at Baseline
Iwama Shintaro, Kobayashi Tomoko, Yasuda Yoshinori, Okuji Takayuki, Ito Masaaki, Ando Masahiko, Zhou Xin, Yamagami Ayana, Onoue Takeshi, Kawaguchi Yohei, Miyata Takashi, Sugiyama Mariko, Takagi Hiroshi, Hagiwara Daisuke, Suga Hidetaka, Banno Ryoichi, Hase Tetsunari, Morise Masahiro, Wakahara Keiko, Yokota Kenji, Kato Masashi, Nishio Naoki, Tanaka Chie, Miyata Kazushi, Ogura Atsushi, Ito Takanori, Sawada Tsunaki, Shimokata Tomoya, Niimi Kaoru, Ohka Fumiharu, Ishigami Masatoshi, Gotoh Momokazu, Hashimoto Naozumi, Saito Ryuta, Kiyoi Hitoshi, Kajiyama Hiroaki, Ando Yuichi, Hibi Hideharu, Sone Michihiko, Akiyama Masashi, Kodera Yasuhiro, Arima Hiroshi
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM Vol. 107 ( 4 ) page： E1620 - E1630 2022.3
Long-Term Efficacy and Safety of Rifaximin in Japanese Patients with Hepatic Encephalopathy: A Multicenter Retrospective Study.
Kawaratani H, Kondo Y, Tatsumi R, Kawabe N, Tanabe N, Sakamaki A, Okumoto K, Uchida Y, Endo K, Kawaguchi T, Oikawa T, Ishizu Y, Hige S, Takami T, Terai S, Ueno Y, Mochida S, Takikawa Y, Torimura T, Matsuura T, Ishigami M, Koike K, Yoshiji H
Journal of clinical medicine Vol. 11 ( 6 ) 2022.3
Patients with low muscle mass have characteristic microbiome with low potential for amino acid synthesis in chronic liver disease.
Yamamoto K, Ishizu Y, Honda T, Ito T, Imai N, Nakamura M, Kawashima H, Kitaura Y, Ishigami M, Fujishiro M
Scientific reports Vol. 12 ( 1 ) page： 3674 2022.3
Changes in the gut microbiome in relation to the degree of gastric mucosal atrophy before and after Helicobacter pylori eradication
Furune Satoshi, Yamamoto Kenta, Honda Takashi, Fujiyoshi Toshihisa, Kakushima Naomi, Furukawa Kazuhiro, Ohno Eizaburo, Nakamura Masanao, Miyahara Ryoji, Kawashima Hiroki, Ishigami Masatoshi, Hirooka Yoshiki, Fujishiro Mitsuhiro
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY Vol. 57 ( 3 ) page： 266 - 273 2022.3
Changes in Body Composition Predict the Time to Treatment Failure of Lenvatinib in Patients with Advanced Hepatocellular Carcinoma: A Pilot Retrospective Study
Yamamoto Takafumi, Imai Norihiro, Kuzuya Teiji, Yokoyama Shinya, Yamamoto Kenta, Ito Takanori, Ishizu Yoji, Honda Takashi, Ishigami Masatoshi
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL page： 1 - 10 2022.3
Fecal incontinence and oral regurgitation during duodenal endoscopic submucosal dissection using the water pressure method
Takada Yoshihisa, Hirose Takashi, Nishida Kazuki, Kakushima Naomi, Furukawa Kazuhiro, Furune Satoshi, Ishikawa Eri, Sawada Tsunaki, Maeda Keiko, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Honda Takashi, Ishigami Masatoshi, Kawashima Hiroki, Fujishiro Mitsuhiro
DIGESTIVE ENDOSCOPY Vol. 34 ( 3 ) page： 526 - 534 2022.3
The impact of the age-adjusted Charlson comorbidity index as a prognostic factor for endoscopic papillectomy in ampullary tumors
Takada Yoshihisa, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Mizutani Yasuyuki, Iida Tadashi, Yamamura Takeshi, Kakushima Naomi, Furukawa Kazuhiro, Nakamura Masanao, Honda Takashi, Ishigami Masatoshi, Ito Akihiro, Hirooka Yoshiki
JOURNAL OF GASTROENTEROLOGY Vol. 57 ( 3 ) page： 199 - 207 2022.3
Artificial intelligence-based diagnosis of upper gastrointestinal subepithelial lesions on endoscopic ultrasonography images
Hirai Keiko, Kuwahara Takamichi, Furukawa Kazuhiro, Kakushima Naomi, Furune Satoshi, Yamamoto Hideko, Marukawa Takahiro, Asai Hiromitsu, Matsui Kenichi, Sasaki Yoji, Sakai Daisuke, Yamada Koji, Nishikawa Takahiro, Hayashi Daijuro, Obayashi Tomohiko, Komiyama Takuma, Ishikawa Eri, Sawada Tsunaki, Maeda Keiko, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Ishigami Masatoshi, Fujishiro Mitsuhiro
GASTRIC CANCER Vol. 25 ( 2 ) page： 382 - 391 2022.3
Preliminary Comparison of Endoscopic Brush and Net Catheters as the Sampling Tool to Analyze the Intestinal Mucus in the Rectum with Ulcerative Colitis Patients
Nakamura Masanao, Maeda Keiko, Yamamoto Kenta, Yamamura Takeshi, Sawada Tsunaki, Ishikawa Eri, Kakushima Naomi, Furukawa Kazuhiro, Iida Tadashi, Mizutani Yasuyuki, Ishikawa Takuya, Ohno Eizaburo, Honda Takashi, Ishigami Masatoshi, Kawashima Hiroki
DIGESTION page： 1 - 12 2022.2
Immunoproliferative Small Intestinal Disease Diagnosed by Double-balloon Endoscopy with Biopsy Sampling.
Meza MRR, Nakamura M, Yamamura T, Maeda K, Sawada T, Ishikawa E, Kakushima N, Furukawa K, Ohno E, Honda T, Kawashima H, Ishigami M
Internal medicine (Tokyo, Japan) 2022.2
Immune-related Liver Injury is a Poor Prognostic Factor in Patients with Nonsmall Cell Lung Cancer Treated with Immune Checkpoint Inhibitors
Yamamoto Takafumi, Ito Takanori, Hase Tetsunari, Ishigami Masatoshi, Mizuno Kazuyuki, Yamamoto Kenta, Imai Norihiro, Ishizu Yoji, Honda Takashi, Shibata Hirofumi, Hatta Takahiro, Yogo Naoyuki, Yasuda Satoshi, Toyoda Hidenori, Abe Takashi, Kawashima Hiroki, Hashimoto Naozumi, Fujishiro Mitsuhiro
CANCER INVESTIGATION Vol. 40 ( 2 ) page： 189 - 198 2022.2
Renal Outcomes With Tenofovir Alafenamide in Liver Transplant Recipients.
Liu JK, Vutien P, Huang DQ, Ishigami M, Landis CS, Nguyen MH, REAL-B Liver Transplant Study Group.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2022.2
Factors related to delayed adverse events of endoscopic submucosal dissection in the duodenum.
Kawamura T, Hirose T, Kakushima N, Furukawa K, Furune S, Ishikawa E, Sawada T, Maeda K, Yamamura T, Ishikawa T, Ohno E, Nakamura M, Honda T, Ishigami M, Kawashima H, Fujishiro M
Digestive diseases (Basel, Switzerland) 2022.2
Absence of large portal collateral vessels is associated with spontaneous improvement of cirrhotic portal vein thrombosis
Yokoyama Shinya, Ishizu Yoji, Honda Takashi, Imai Norihiro, Ito Takanori, Yamamoto Kenta, Tsuzuki Tomoyuki, Ishigami Masatoshi
HEPATOLOGY RESEARCH Vol. 52 ( 2 ) page： 199 - 209 2022.2
Initial experience of tofacitinib for treating refractory moderate-to-severe ulcerative colitis
Nakamura Masanao, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Eri, Ishikawa Takuya, Kakushima Naomi, Furukawa Kazuhiro, Ohno Eizaburo, Kawashima Hiroki, Honda Takashi, Ishigami Masatoshi, Fujishiro Mitsuhiro
NAGOYA JOURNAL OF MEDICAL SCIENCE Vol. 84 ( 1 ) page： 169 - 179 2022.2
Comparison of outcomes between secondary fully covered and uncovered self-expandable metal stents in the treatment of recurrent biliary obstruction of pancreatic cancer
Kataoka Kunio, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Mizutani Yasuyuki, Iida Tadashi, Furukawa Kazuhiro, Nakamura Masanao, Honda Takashi, Ishigami Masatoshi, Fujishiro Mitsuhiro
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES 2022.1
Evaluation of ulcerative colitis activity using transabdominal ultrasound shear wave elastography
Yamada Kenta, Ishikawa Takuya, Kawashima Hiroki, Ohno Eizaburo, Iida Tadashi, Ishikawa Eri, Mizutani Yasuyuki, Sawada Tsunaki, Maeda Keiko, Yamamura Takeshi, Kakushima Naomi, Furukawa Kazuhiro, Nakamura Masanao, Ishigami Masatoshi, Fujishiro Mitsuhiro
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY Vol. 12 ( 1 ) page： 618 - 626 2022.1
Feasibility of endoscopic ultrasonography using a 60-MHz ultrasound miniature probe in the upper gastrointestinal tract
Asai Hiromitsu, Furukawa Kazuhiro, Miyahara Ryoji, Funasaka Kohei, Furune Satoshi, Nakamura Masanao, Kawashima Hiroki, Ishigami Masatoshi, Hirooka Yoshiki, Fujishiro Mitsuhiro
JOURNAL OF MEDICAL ULTRASONICS Vol. 49 ( 1 ) page： 61 - 69 2022.1
Fish bone migration after pancreaticoduodenectomy: Incidence and treatment options
Takada Yoshihisa, Ishikawa Takuya, Kawashima Hiroki, Mizutani Yasuyuki, Ohno Eisaburo, Iida Tadashi, Ogawa Hiroshi, Hayashi Masamichi, Takami Hideki, Onoe Shunsuke, Ishigami Masatoshi
JOURNAL OF DIGESTIVE DISEASES Vol. 23 ( 1 ) page： 44 - 49 2022.1
Differentiation Between Solid Pseudopapillary Neoplasm of the Pancreas and Nonfunctional Pancreatic Neuroendocrine Neoplasm Using Endoscopic Ultrasound
Kataoka Kunio, Ishikawa Takuya, Ohno Eizaburo, Mizutani Yasuyuki, Iida Tadashi, Furukawa Kazuhiro, Nakamura Masanao, Honda Takashi, Ishigami Masatoshi, Kawashima Hiroki, Hirooka Yoshiki, Fujishiro Mitsuhiro
PANCREAS Vol. 51 ( 1 ) page： 106 - 111 2022.1
The influence of hepatitis C virus eradication on hepatocarcinogenesis in patients with hemophilia HCC after HCV eradication in hemophilia
Inukai Yosuke, Imai Norihiro, Yamamoto Kenta, Ito Takanori, Ishizu Yoji, Honda Takashi, Okamoto Shuichi, Kanematsu Takeshi, Suzuki Nobuaki, Matsushita Tadashi, Ishigami Masatoshi, Fujishiro Mitsuhiro
ANNALS OF HEPATOLOGY Vol. 27 ( 1 ) page： 100545 2022
Indications and Limitations Associated with the Patency Capsule Prior to Capsule Endoscopy
Nakamura Masanao, Kawashima Hiroki, Ishigami Masatoshi, Fujishiro Mitsuhiro
INTERNAL MEDICINE Vol. 61 ( 1 ) page： 5 - 13 2022
Real-world local recurrence rate after cold polypectomy in colorectal polyps less than 10 mm using propensity score matching
Saito Masashi, Yamamura Takeshi, Nakamura Masanao, Maeda Keiko, Sawada Tsunaki, Ishikawa Eri, Mizutani Yasuyuki, Ishikawa Takuya, Kakushima Naomi, Furukawa Kazuhiro, Ohno Eizaburo, Kawashima Hiroki, Ishigami Masatoshi, Fujishiro Mitsuhiro
WORLD JOURNAL OF GASTROENTEROLOGY Vol. 27 ( 47 ) page： 8182 - 8193 2021.12
Changes in the gut microbiota after hepatitis C virus eradication
Honda Takashi, Ishigami Masatoshi, Yamamoto Kenta, Takeyama Tomoaki, Ito Takanori, Ishizu Yoji, Kuzuya Teiji, Nakamura Masanao, Kawashima Hiroki, Miyahara Ryoji, Ishikawa Tetsuya, Hirooka Yoshiki, Fujishiro Mitsuhiro
SCIENTIFIC REPORTS Vol. 11 ( 1 ) page： 23568 2021.12
Obesity and myosteatosis: the two characteristics of dynapenia in patients with cirrhosis
Sugiyama Yoshiaki, Ishizu Yoji, Ando Yusuke, Yokoyama Shinya, Yamamoto Kenta, Ito Takanori, Imai Norihiro, Nakamura Masanao, Honda Takashi, Kawashima Hiroki, Ishikawa Tetsuya, Ishigami Masatoshi
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY Vol. 33 ( 1S Suppl 1 ) page： E916 - E921 2021.12
Clinical characteristics of gastrointestinal immune-related adverse events of immune checkpoint inhibitors and their association with survival
Yamada Kentaro, Sawada Tsunaki, Nakamura Masanao, Yamamura Takeshi, Maeda Keiko, Ishikawa Eri, Iida Tadashi, Mizutani Yasuyuki, Kakushima Naomi, Ishikawa Takuya, Furukawa Kazuhiro, Ohno Eizaburo, Honda Takashi, Kawashima Hiroki, Ishigami Masatoshi, Furune Satoshi, Hase Tetsunari, Yokota Kenji, Maeda Osamu, Hashimoto Naozumi, Akiyama Masashi, Ando Yuichi, Fujishiro Mitsuhiro
WORLD JOURNAL OF GASTROENTEROLOGY Vol. 27 ( 41 ) page： 7190 - 7206 2021.11
Safety and Efficacy of Glass Membrane Pumping Emulsification Device in Transarterial Chemoembolization for Hepatocellular Carcinoma: First Clinical Outcomes
Imai Norihiro, Yokoyama Shinya, Yamamoto Kenta, Ito Takanori, Ishizu Yoji, Honda Takashi, Ishigami Masatoshi
ANTICANCER RESEARCH Vol. 41 ( 11 ) page： 5817 - 5820 2021.11
Microbiome, fibrosis and tumor networks in a non-alcoholic steatohepatitis model of a choline-deficient high-fat diet using diethylnitrosamine
Yamamoto Kenta, Honda Takashi, Yokoyama Shinya, Ma Lingyun, Kato Asuka, Ito Takanori, Ishizu Yoji, Kuzuya Teiji, Nakamura Masanao, Kawashima Hiroki, Ishigami Masatoshi, Tsuji Noriko M., Fujishiro Mitsuhiro
DIGESTIVE AND LIVER DISEASE Vol. 53 ( 11 ) page： 1443 - 1450 2021.11
Clinical course of liver injury induced by immune checkpoint inhibitors in patients with advanced malignancies
Ito Takanori, Ishigami Masatoshi, Yamamoto Takafumi, Mizuno Kazuyuki, Yamamoto Kenta, Imai Norihiro, Ishizu Yoji, Honda Takashi, Kawashima Hiroki, Yasuda Satoshi, Toyoda Hidenori, Yokota Kenji, Hase Tetsunari, Nishio Naoki, Maeda Osamu, Kato Masashi, Hashimoto Naozumi, Hibi Hideharu, Kodera Yasuhiro, Sone Michihiko, Ando Yuichi, Akiyama Masashi, Shimoyama Yoshie, Fujishiro Mitsuhiro
HEPATOLOGY INTERNATIONAL Vol. 15 ( 5 ) page： 1278 - 1287 2021.10
Differentiation between pancreatic metastases from renal cell carcinoma and pancreatic neuroendocrine neoplasm using endoscopic ultrasound
Kataoka Kunio, Ishikawa Takuya, Ohno Eizaburo, Mizutani Yasuyuki, Iida Tadashi, Ishikawa Eri, Furukawa Kazuhiro, Nakamura Masanao, Honda Takashi, Ishigami Masatoshi, Kawashima Hiroki, Hirooka Yoshiki, Fujishiro Mitsuhiro
PANCREATOLOGY Vol. 21 ( 7 ) page： 1364 - 1370 2021.10
Factors associated with bleeding after endoscopic variceal ligation in children
Yokoyama Shinya, Ishizu Yoji, Ishigami Masatoshi, Honda Takashi, Kuzuya Teiji, Ito Takanori, Hinoki Akinari, Sumida Wataru, Shirota Chiyoe, Tainaka Takahisa, Makita Satoshi, Yokota Kazuki, Uchida Hiroo, Fujishiro Mitsuhiro
PEDIATRICS INTERNATIONAL Vol. 63 ( 10 ) page： 1223 - 1229 2021.10
RENAL OUTCOMES IN POST-LIVER TRANSPLANT RECIPIENTS TREATED WITH TENOFOVIR ALAFENAMIDE COMPARED WITH TENOFOVIR DISOPROXIL FUMARATE AND ENTECAVIR
Liu Joanne, Vutien Philip, Huang Daniel, Ishigami Masatoshi, Daniel Peter Chen Yang Nikhil, Ito Takanori, Dang Hansen, Maeda Mayumi, Leong Jennifer, Landis Charles, Nguyen Mindie H.
HEPATOLOGY Vol. 74 page： 492A - 493A 2021.10
Conditioned medium from stem cells derived from human exfoliated deciduous teeth ameliorates NASH via the Gut-Liver axis
Muto Hisanori, Ito Takanori, Tanaka Taku, Yokoyama Shinya, Yamamoto Kenta, Imai Norihiro, Ishizu Yoji, Maeda Keiko, Honda Takashi, Ishikawa Tetsuya, Kato Asuka, Ohshiro Taichi, Kano Fumiya, Yamamoto Akihito, Sakai Kiyoshi, Hibi Hideharu, Ishigami Masatoshi, Fujishiro Mitsuhiro
SCIENTIFIC REPORTS Vol. 11 ( 1 ) page： 18778 2021.9
Revisiting Prognosis After Liver Transplant in Patients Positive for Hepatitis C Virus: Focus on Hepatitis C Recurrence-Unrelated Complications
Ishigami Masatoshi, Honda Takashi, Ishizu Yoji, Imai Norihiro, Ito Takanori, Yamamoto Kenta, Kamei Hideya, Ogura Yasuhiro, Fujishiro Mitsuhiro
EXPERIMENTAL AND CLINICAL TRANSPLANTATION Vol. 19 ( 9 ) page： 935 - 942 2021.9
Transient deterioration of albumin-bilirubin scores in early post-dose period of molecular targeted therapies in advanced hepatocellular carcinoma with 50% or higher liver occupation A STROBE-compliant retrospective observational study
Muto Hisanori, Kuzuya Teiji, Ito Takanori, Ishizu Yoji, Honda Takashi, Ishikawa Tetsuya, Ishigami Masatoshi, Fujishiro Mitsuhiro
MEDICINE Vol. 100 ( 31 ) page： e26820 2021.8
The sodium-glucose cotransporter-2 inhibitor Tofogliflozin prevents the progression of nonalcoholic steatohepatitis-associated liver tumors in a novel murine model
Yoshioka Naoki, Tanaka Miyako, Ochi Kozue, Watanabe Akiko, Ono Kenji, Sawada Makoto, Ogi Tomoo, Itoh Michiko, Ito Ayaka, Shiraki Yukihiro, Enomoto Atsushi, Ishigami Masatoshi, Fujishiro Mitsuhiro, Ogawa Yoshihiro, Suganami Takayoshi
BIOMEDICINE & PHARMACOTHERAPY Vol. 140 page： 111738 2021.8
Feasibility of patency capsule and colon capsule endoscopy in patients with suspected gastrointestinal stenosis: a prospective study
Otsuka Hiroyuki, Nakamura Masanao, Yamamura Takeshi, Maeda Keiko, Sawade Tsunaki, Mizutani Yasuyuki, Ishikawa Eri, Ishikawa Takuya, Kakushima Naomi, Furukawa Kazuhiro, Ohno Eizaburo, Kawashima Iliroki, Honda Takashi, Ishigami Masatoshi, Fujishiro Mitsuhiro
NAGOYA JOURNAL OF MEDICAL SCIENCE Vol. 83 ( 3 ) page： 419 - 430 2021.8
The impact of hepatitis C virus eradication on hepatocarcinogenesis in haemophiliacs
Inukai Yosuke, Imai Norihiro, Yamamoto Kenta, Ito Takanori, Ishizu Yoji, Honda Takashi, Ishigami Masatoshi
JOURNAL OF HEPATOLOGY Vol. 75 page： S787 - S788 2021.7
Endoscopic papillectomy for ampullary adenoma and early adenocarcinoma: Analysis of factors related to treatment outcome and long-term prognosis
Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Iida Tadashi, Tanaka Hiroyuki, Furukawa Kazuhiro, Nakamura Masanao, Honda Takashi, Hashimoto Senju, Itoh Akihiro, Ishigami Masatoshi, Hirooka Yoshiki, Fujishiro Mitsuhiro
DIGESTIVE ENDOSCOPY Vol. 33 ( 5 ) page： 858 - 869 2021.7
Lewis score on capsule endoscopy can predict the prognosis in patients with small bowel lesions of Crohn's disease
Nishikawa Takahiro, Nakamura Masanao, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Eri, Ishikawa Takuya, Kakushima Naomi, Furukawa Kazuhiro, Ohno Eizaburo, Honda Takashi, Kawashima Hiroki, Ishigami Masatoshi, Fujishiro Mitsuhiro
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 36 ( 7 ) page： 1851 - 1858 2021.7
Quality of Life in patients with nonalcoholic fatty liver disease: Structure and related factors focusing on illness uncertainty
Ozawa Naoki, Sato Kazuki, Sugimura Ayumi, Maki Shigeyoshi, Tanaka Taku, Yamamoto Kenta, Ito Takanori, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Ishigami Masatoshi, Fujishiro Mitsuhiro, Ishikawa Tetsuya, Ando Shoko
JAPAN JOURNAL OF NURSING SCIENCE Vol. 18 ( 3 ) page： e12415 2021.7
An initial trial of quantitative evaluation of autoimmune pancreatitis using shear wave elastography and shear wave dispersion in transabdominal ultrasound
Suzuki Hirotaka, Ishikawa Takuya, Ohno Eizaburo, Iida Tadashi, Uetsuki Kota, Yashika Jun, Yamada Kenta, Yoshikawa Masakatsu, Furukawa Kazuhiro, Nakamura Masanao, Honda Takashi, Ishigami Masatoshi, Kawashima Hiroki, Fujishiro Mitsuhiro
PANCREATOLOGY Vol. 21 ( 4 ) page： 682 - 687 2021.6
Immunohistochemical staining for IMP3 in patients with duodenal papilla tumors: assessment of the potential for diagnosing endoscopic resectability and predicting prognosis
Tanaka Hiroyuki, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Iida Tadashi, Ishikawa Eri, Furukawa Kazuhiro, Nakamura Masanao, Honda Takashi, Shimoyama Yoshie, Miyahara Ryoji, Kawabe Naoto, Kuzuya Teiji, Hashimoto Senju, Ishigami Masatoshi, Hirooka Yoshiki, Fujishiro Mitsuhiro
BMC GASTROENTEROLOGY Vol. 21 ( 1 ) page： 224 2021.5
Measurement of fasting breath hydrogen concentration as a simple diagnostic method for pancreatic exocrine insufficiency
Uetsuki Kota, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Iida Tadashi, Yamamoto Kenta, Furukawa Kazuhiro, Nakamura Masanao, Honda Takashi, Ishigami Masatoshi, Hirooka Yoshiki, Fujishiro Mitsuhiro
BMC GASTROENTEROLOGY Vol. 21 ( 1 ) page： 211 2021.5
Tolerability of Molecular-targeted Agents for Hepatocellular Carcinoma Treatment in Haemophiliacs
Yamamoto Takafumi, Imai Norihiro, Yamamoto Kenta, Ito Takanori, Ishizu Yoji, Honda Takashi, Okamoto Shuichi, Kanematsu Takeshi, Suzuki Nobuaki, Matsushita Tadashi, Ishigami Masatoshi, Fujishiro Mitsuhiro
ANTICANCER RESEARCH Vol. 41 ( 5 ) page： 2569 - 2573 2021.5
Clinical Features of Ischemic Enteritis Diagnosed by Double-Balloon Endoscopy
Nakamura Masanao, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Eri, Kakushima Naomi, Furukawa Kazuhiro, Ishikawa Takuya, Ohno Eizaburo, Honda Takashi, Kawashima Hiroki, Ishigami Masatoshi, Fujishiro Mitsuhiro
CANADIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 2021 page： 8875564 2021.4
Variability measurements provide additional value to shear wave elastography in the diagnosis of pancreatic cancer
Yoshikawa Masakatsu, Ishikawa Takuya, Ohno Eizaburo, Iida Tadashi, Furukawa Kazuhiro, Nakamura Masanao, Honda Takashi, Ishigami Masatoshi, Kinoshita Fumie, Kawashima Hiroki, Fujishiro Mitsuhiro
SCIENTIFIC REPORTS Vol. 11 ( 1 ) page： 7409 2021.4
Filtrated Adipose Tissue-Derived Mesenchymal Stem Cell Lysate Ameliorates Experimental Acute Colitis in Mice
Nishikawa Takahiro, Maeda Keiko, Nakamura Masanao, Yamamura Takeshi, Sawada Tsunaki, Mizutani Yasuyuki, Ito Takanori, Ishikawa Takuya, Furukawa Kazuhiro, Ohno Eizaburo, Miyahara Ryoji, Kawashima Hiroki, Honda Takashi, Ishigami Masatoshi, Yamamoto Tokunori, Matsumoto Seiji, Hotta Yuji, Fujishiro Mitsuhiro
DIGESTIVE DISEASES AND SCIENCES Vol. 66 ( 4 ) page： 1034 - 1044 2021.4
Impact of visceral fat accumulation on the prognosis of patients with cirrhosis
Ishizu Yoji, Ishigami Masatoshi, Honda Takashi, Imai Norihiro, Ito Takanori, Yamamoto Kenta, Fujishiro Mitsuhiro
CLINICAL NUTRITION ESPEN Vol. 42 page： 354 - 360 2021.4
The epidemiology of NAFLD and lean NAFLD in Japan: a meta-analysis with individual and forecasting analysis, 1995-2040
Ito Takanori, Ishigami Masatoshi, Zou Biyao, Tanaka Taku, Takahashi Hirokazu, Kurosaki Masayuki, Maeda Mayumi, Thin Khin Naing, Tanaka Kenichi, Takahashi Yuka, Itoh Yoshito, Oniki Kentaro, Seko Yuya, Saruwatari Junji, Kawanaka Miwa, Atsukawa Masanori, Hyogo Hideyuki, Ono Masafumi, Ogawa Eiichi, Barnett Scott D., Stave Christopher D., Cheung Ramsey C., Fujishiro Mitsuhiro, Eguchi Yuichiro, Toyoda Hidenori, Nguyen Mindie H.
HEPATOLOGY INTERNATIONAL Vol. 15 ( 2 ) page： 366 - 379 2021.4
Endoscopic ultrasound elastography for small solid pancreatic lesions with or without main pancreatic duct dilatation
Kataoka Kunio, Ishikawa Takuya, Ohno Eizaburo, Iida Tadashi, Suzuki Hirotaka, Uetsuki Kota, Furukawa Kazuhiro, Nakamura Masanao, Honda Takashi, Ishigami Masatoshi, Kawashima Hiroki, Hirooka Yoshiki, Fujishiro Mitsuhiro
PANCREATOLOGY Vol. 21 ( 2 ) page： 451 - 458 2021.3
Simplification of balloon-occluded retrograde transcatheter obliteration procedure using a coaxial double balloon catheter compared with a single-balloon catheter
Ishizu Yoji, Ishigami Masatoshi, Honda Takashi, Kuzuya Teiji, Ito Takanori, Komada Tomohiro, Fujishiro Mitsuhiro
JAPANESE JOURNAL OF RADIOLOGY Vol. 39 ( 3 ) page： 296 - 302 2021.3
The relationship between oral-origin bacteria in the fecal microbiome and albumin-bilirubin grade in patients with hepatitis C
Yamamoto Kenta, Honda Takashi, Ito Takanori, Ishizu Yoji, Kuzuya Teiji, Nakamura Masanao, Miyahara Ryoji, Kawashima Hiroki, Ishigami Masatoshi, Fujishiro Mitsuhiro
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 36 ( 3 ) page： 790 - 799 2021.3
Utility of multiphase contrast enhancement patterns on CEH-EUS for the differential diagnosis of IPMN-derived and conventional pancreatic cancer
Yashika Jun, Ohno Eizaburo, Ishikawa Takuya, Iida Tadashi, Suzuki Hirotaka, Uetsuki Kota, Yamada Kenta, Yoshikawa Masakatsu, Gibo Noriaki, Shimoyama Yoshie, Ishikawa Eri, Furukawa Kazuhiro, Nakamura Masanao, Honda Takashi, Ishigami Masatoshi, Hirooka Yoshiki, Kawashima Hiroki, Fujishiro Mitsuhiro
PANCREATOLOGY Vol. 21 ( 2 ) page： 390 - 396 2021.3
Diagnostic yield of colon capsule endoscopy for Crohn's disease lesions in the whole gastrointestinal tract
Yamada Keisaku, Nakamura Masanao, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Eri, Ishikawa Takuya, Kakushima Naomi, Furukawa Kazuhiro, Ohno Eizaburo, Kawashima Hiroki, Honda Takashi, Ishigami Masatoshi, Fujishiro Mitsuhiro
BMC GASTROENTEROLOGY Vol. 21 ( 1 ) page： 75 2021.2
Ustekinumab is effective against small bowel lesions in Crohn's disease: two case reports
Murate Kentaro, Nakamura Masanao, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Eri, Kakushima Naomi, Furukawa Kazuhiro, Ohno Eizaburo, Honda Takashi, Kawashima Hiroki, Ishigami Masatoshi, Fujishiro Mitsuhiro
CLINICAL JOURNAL OF GASTROENTEROLOGY Vol. 14 ( 1 ) page： 129 - 135 2021.2
Hepatitis B Core-Related Antigen to Indicate High Viral Load: Systematic Review and Meta-Analysis of 10,397 Individual Participants
Yoshida Kyoko, Desbiolles Alice, Feldman Sarah F., Ahn Sang Hoon, Alidjinou Enagnon K., Atsukawa Masanori, Bocket Laurence, Brunetto Maurizia R., Buti Maria, Carey Ivana, Caviglia Gian Paolo, Chen En-Qiang, Cornberg Markus, Enomoto Masaru, Honda Masao, Zu Siederdissen Christoph Hoener, Ishigami Masatoshi, Janssen Harry L. A., Maasoumy Benjamin, Matsui Takeshi, Matsumoto Akihiro, Nishiguchi Shuhei, Riveiro-Barciela Mar, Takaki Akinobu, Tangkijvanich Pisit, Toyoda Hidenori, van Campenhout Margo J. H., Wang Bo, Wei Lai, Yang Hwai- I, Yano Yoshihiko, Yatsuhashi Hiroshi, Yuen Man-Fung, Tanaka Eiji, Lemoine Maud, Tanaka Yasuhito, Shimakawa Yusuke
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY Vol. 19 ( 1 ) page： 46 - + 2021.1
Safety and efficacy of percutaneous radiofrequency ablation for hepatocellular carcinoma patients with haemophilia
Yamamoto Takafumi, Imai Norihiro, Yamamoto Kenta, Ito Takanori, Ishizu Yoji, Honda Takashi, Okamoto Shuichi, Kanematsu Takeshi, Suzuki Nobuaki, Matsushita Tadashi, Ishigami Masatoshi, Fujishiro Mitsuhiro
HAEMOPHILIA Vol. 27 ( 1 ) page： 100 - 107 2021.1
Systematic review and meta-analysis of the diagnostic and therapeutic yield of small bowel endoscopy in patients with overt small bowel bleeding
Uchida Genta, Nakamura Masanao, Yamamura Takeshi, Furukawa Kazuhiro, Kawashima Hiroki, Honda Takashi, Ishigami Masatoshi, Fujishiro Mitsuhiro
DIGESTIVE ENDOSCOPY Vol. 33 ( 1 ) page： 66 - 82 2021.1
Amino Acid Polymorphism in Hepatitis B Virus Associated With Functional Cure
Honda Takashi, Yamada Norie, Murayama Asako, Shiina Masaaki, Aly Hussein Hassan, Kato Asuka, Ito Takanori, Ishizu Yoji, Kuzuya Teiji, Ishigami Masatoshi, Murakami Yoshiki, Tanaka Tomohisa, Moriishi Kohji, Nishitsuji Hironori, Shimotohno Kunitada, Ishikawa Tetsuya, Fujishiro Mitsuhiro, Muramatsu Masamichi, Wakita Takaji, Kato Takanobu
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY Vol. 12 ( 5 ) page： 1583 - 1598 2021
Progression After Molecular Targeted Agents: Hepatic Arterial Changes and Transarterial Chemoembolization in Hepatocellular Carcinoma
Matsuda Noritaka, Imai Norihiro, Kuzuya Teiji, Yamamoto Kenta, Ito Takanori, Ishizu Yoji, Honda Takashi, Ishigami Masatoshi, Fujishiro Mitsuhiro
IN VIVO Vol. 35 ( 2 ) page： 1185 - 1189 2021
The microbiome can predict mucosal healing in small intestine in patients with Crohn's disease
Hattori Shun, Nakamura Masanao, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Yamamoto Kenta, Ishikawa Takuya, Furukawa Kazuhiro, Ohno Eizaburo, Honda Takashi, Kawashima Hiroki, Ishigami Masatoshi, Hirooka Yoshiki, Fujishiro Mitsuhiro
JOURNAL OF GASTROENTEROLOGY Vol. 55 ( 12 ) page： 1138 - 1149 2020.12
Accuracy of carbon dioxide insufflation for endoscopic retrograde cholangiopancreatography using double-balloon endoscopy
Niwa Yoshiki, Nakamura Masanao, Kawashima Hiroki, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Eri, Ishikawa Takuya, Kakushima Naomi, Furukawa Kazuhiro, Ohno Eizaburo, Honda Takashi, Ishigami Masatoshi, Fujishiro Mitsuhiro
WORLD JOURNAL OF GASTROENTEROLOGY Vol. 26 ( 42 ) page： 6669 - 6678 2020.11
AMINO ACID POLYMORPHISM IN HEPATITIS B VIRUS ASSOCIATED WITH NATURAL CLEARANCE OF HBV DNA AND HBsAg
Honda Takashi, Yamada None, Murayama Asako, Kato Asuka, Ito Takanori, Ishizu Yoji, Kuzuya Teiji, Ishigami Masatoshi, Murakami Yoshiki, Ishikawa Tetsuya, Fujishiro Mitsuhiro, Kato Takanobu
HEPATOLOGY Vol. 72 page： 508A - 509A 2020.11
Endoscopic Activity and Serum TNF-alpha Level at Baseline Are Associated With Clinical Response to Ustekinumab in Crohn's Disease Patients
Murate Kentaro, Maeda Keiko, Nakamura Masanao, Sugiyama Daisuke, Wada Hirotaka, Yamamura Takeshi, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Takuya, Furukawa Kazuhiro, Ohno Eizaburo, Honda Takashi, Kawashima Hiroki, Miyahara Ryoji, Ishigami Masatoshi, Nishikawa Hiroyoshi, Fujishiro Mitsuhiro
INFLAMMATORY BOWEL DISEASES Vol. 26 ( 11 ) page： 1669 - 1681 2020.11
GUT MICROBIOTA ASSOCIATED WITH THE DIFFERENCE BETWEEN PATIENTS WITH AND WITHOUT HEPATOCELLULAR CARCINOMA IN CHRONIC LIVER DISEASE
Honda Takashi, Ishigami Masatoshi, Yamamoto Kenta, Ito Takanori, Imai Norihiro, Ishizu Yoji, Fujishiro Mitsuhiro
HEPATOLOGY Vol. 72 page： 370A - 370A 2020.11
IMPROVEMENT OF LIVER FUNCTIONAL RESERVE AFTER SVR IN HCV-PATIENTS WITH COMPENSATED, SEVERE FIBROSIS BY IFN-FREE, DAA COMBINATION TREATMENT-IMPACT OF PRETREATMENT SERUM AFP LEVELS
Ishigami Masatoshi, Honda Takashi, Ishizu Yoji, Imai Norihiro, Ito Takanori, Yamamoto Kenta, Fujishiro Mitsuhiro
HEPATOLOGY Vol. 72 page： 564A - 565A 2020.11
SAFETY AND EFFICACY OF PERCUTANEOUS RADIOFREQUENCY ABLATION FOR HEPATOCELLULAR CARCINOMA PATIENTS WITH HEMOPHILIA
Yamamoto Takafumi, Ishigami Masatoshi, Yamamoto Kenta, Ito Takanori, Imai Norihiro, Lshizu Yoji, Honda Takashi, Fujishiro Mitsuhiro
HEPATOLOGY Vol. 72 page： 705A - 706A 2020.11
THE EPIDEMIOLOGY OF NAFLD AND LEAN NAFLD IN JAPAN: A SYSTEMATIC REVIEW AND META-ANALYSIS WITH INDIVIDUAL PATIENT LEVEL DATA AND FORECASTING, 1995-2040
Ito Takanori, Ishigami Masatoshi, Zou Biyao, Tanaka Taku, Takahashi Hirokazu, Kurosaki Masayuki, Maeda Mayumi, Thin Khin Naing, Tanaka Kenichi, Takahashi Yuka, Itoh Yoshito, Oniki Kentaro, Seko Yuya, Saruwatari Junji, Kawanaka Miwa, Atsukawa Masanori, Hyogo Hideyuki, Ono Masafumi, Ogawa Eiichi, Barnette Scott D., Stave Christopher Donald, Cheung Ramsey, Fujishiro Mitsuhiro, Eguchi Yuichiro, Toyoda Hidenori, Nguyen Mindie H.
HEPATOLOGY Vol. 72 page： 999 - 999 2020.11
The albumin-bilirubin score as a predictor of outcomes in Japanese patients with PBC: an analysis using time-dependent ROC
Ito Takanori, Ishigami Masatoshi, Morooka Hikaru, Yamamoto Kenta, Imai Norihiro, Ishizu Yoji, Honda Takashi, Nishimura Daisaku, Tada Toshifumi, Yasuda Satoshi, Toyoda Hidenori, Kumada Takashi, Fujishiro Mitsuhiro
SCIENTIFIC REPORTS Vol. 10 ( 1 ) page： 17812 2020.10
Drug-Induced Liver Injury by Checkpoint Inhibitors: Benefit of a Causality Assessment Tool
Weber Sabine, Benesic Andreas, Ishigami Masatoshi, Gerbes Alexander L.
HEPATOLOGY COMMUNICATIONS Vol. 4 ( 10 ) page： 1552 - 1554 2020.10
What is the role of measuring shear wave dispersion using shear wave elastography in pancreatic parenchyma?
Suzuki Hirotaka, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Hashimoto Senju, Nakamura Masanao, Miyahara Ryoji, Ishigami Masatoshi, Hirooka Yoshiki, Fujishiro Mitsuhiro
JOURNAL OF MEDICAL ULTRASONICS Vol. 47 ( 4 ) page： 575 - 581 2020.10
Efficacy and Safety of Sorafenib in Unresectable Hepatocellular Carcinoma with Bile Duct Invasion
Tanaka Taku, Kuzuya Teiji, Ishigami Masatoshi, Ito Takanori, Ishizu Yoji, Honda Takashi, Ishikawa Tetsuya, Fujishiro Mitsuhiro
ONCOLOGY Vol. 98 ( 9 ) page： 621 - 629 2020.9
Revisiting the indications for liver transplantation in cirrhotic patients considering the long-term outcomes of cirrhotic patients
Ishigami Masatoshi, Honda Takashi, Kuzuya Teiji, Ishizu Yoji, Ito Takanori, Kamei Hideya, Ogura Yasuhiro, Fujishiro Mitsuhiro
JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES Vol. 27 ( 9 ) page： 655 - 662 2020.9
Limitation of non-transplant treatment and proper timing for liver transplantation in patients with hepatocellular carcinoma considering long-term survival
Nomura Aya, Ishigami Masatoshi, Honda Takashi, Kuzuya Teiji, Ishizu Yoji, Ito Takanori, Kamei Hideya, Onishi Yasuharu, Ogura Yasuhiro, Fujishiro Mitsuhiro
MEDICINE Vol. 99 ( 28 ) page： e21161 2020.7
Serum Nutritional Markers as Prognostic Factors for Hepatic and Extrahepatic Carcinogenesis in Japanese Patients with Nonalcoholic Fatty Liver Disease
Ito Takanori, Ishigami Masatoshi, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Ishikawa Tetsuya, Toyoda Hidenori, Kumada Takashi, Fujishiro Mitsuhiro
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL Vol. 72 ( 5 ) page： 884 - 891 2020.7
Complete response of advanced hepatocellular carcinoma achieved by sorafenib dose re-escalation after failure of long-term low-dose-sorafenib treatment combined with transcatheter arterial chemoembolization: a case report
Muto Hisanori, Kuzuya Teiji, Ito Takanori, Ishizu Yoji, Honda Takashi, Ishikawa Tetsuya, Ishigami Masatoshi, Fujishiro Mitsuhiro
CLINICAL JOURNAL OF GASTROENTEROLOGY Vol. 13 ( 3 ) page： 397 - 402 2020.6
Correlation of serum zinc levels with pathological and laboratory findings in patients with nonalcoholic fatty liver disease
Ito Takanori, Ishigami Masatoshi, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Ishikawa Tetsuya, Toyoda Hidenori, Kumada Takashi, Fujishiro Mitsuhiro
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY Vol. 32 ( 6 ) page： 748 - 753 2020.6
Real world data of liver injury induced by immune checkpoint inhibitors in Japanese patients with advanced malignancies
Mizuno Kazuyuki, Ito Takanori, Ishigami Masatoshi, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Kawashima Hiroki, Inukai Yosuke, Toyoda Hidenori, Yokota Kenji, Hase Tetsunari, Maeda Osamu, Kiyoi Hitoshi, Nagino Masato, Hibi Hideharu, Kodera Yasuhiro, Fujimoto Yasushi, Sone Michihiko, Gotoh Momokazu, Ando Yuichi, Akiyama Masashi, Hasegawa Yoshinori, Fujishiro Mitsuhiro
JOURNAL OF GASTROENTEROLOGY Vol. 55 ( 6 ) page： 653 - 661 2020.6
Association Between Fibrosis Stage and Outcomes of Patients With Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta -Analysis
Taylor Rod S., Taylor Rebecca J., Bayliss Sue, Hagstrom Hannes, Nasr Patrik, Schattenberg Jorn M., Ishigami Masatoshi, Toyoda Hidenori, Wong Vincent Wai-Sun, Peleg Noam, Shlomai Amir, Sebastiani Giada, Seko Yuya, Bhala Neeraj, Younossi Zobair M., Anstee Quentin M., McPherson Stuart, Newsome Philip N.
GASTROENTEROLOGY Vol. 158 ( 6 ) page： 1611 - + 2020.5
Association Between Fibrosis Stage and Outcomes of Patients With Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis.
Taylor RS, Taylor RJ, Bayliss S, Hagström H, Nasr P, Schattenberg JM, Ishigami M, Toyoda H, Wai-Sun Wong V, Peleg N, Shlomai A, Sebastiani G, Seko Y, Bhala N, Younossi ZM, Anstee QM, McPherson S, Newsome PN
Gastroenterology Vol. 158 ( 6 ) page： 1611 - 1625.e12 2020.5
Nonexposed wall-inversion surgery as a novel local resection method for neoplasms in the gastrointestinal tract
Fujishiro Mitsuhiro, Furukawa Kazuhiro, Yamamura Takeshi, Nakamura Masanao, Honda Takashi, Maeda Osamu, Ishigami Masatoshi, Kawashima Hiroki
NAGOYA JOURNAL OF MEDICAL SCIENCE Vol. 82 ( 2 ) page： 175 - 182 2020.5
Initial Experience of Ramucirumab Treatment After Lenvatinib Failure for Patients With Advanced Hepatocellular Carcinoma
Kuzuya Teiji, Ishigami Masatoshi, Ito Takanori, Ishizu Yoji, Honda Takashi, Ishikawa Tetsuya, Fujishiro Mitsuhiro
ANTICANCER RESEARCH Vol. 40 ( 4 ) page： 2089 - 2093 2020.4
Sorafenib vs. Lenvatinib as First-line Therapy for Advanced Hepatocellular Carcinoma With Portal Vein Tumor Thrombosis
Kuzuya Teiji, Ishigami Masatoshi, Ito Takanori, Ishizu Yoji, Honda Takashi, Ishikawa Tetsuya, Fujishiro Mitsuhiro
ANTICANCER RESEARCH Vol. 40 ( 4 ) page： 2283 - 2290 2020.4
Diagnosis of vascular invasion in pancreatic ductal adenocarcinoma using endoscopic ultrasound elastography
Yamada Kenta, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Tanaka Hiroyuki, Nakamura Masanao, Miyahara Ryoji, Ishigami Masatoshi, Hirooka Yoshiki, Fujishiro Mitsuhiro
BMC GASTROENTEROLOGY Vol. 20 ( 1 ) page： 81 2020.3
Double-balloon endoscopic retrograde cholangiopancreatography for patients who underwent liver operation: A retrospective study
Nishio Ryo, Kawashima Hiroki, Nakamura Masanao, Ohno Eizaburo, Ishikawa Takuya, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Tanaka Hiroyuki, Sakai Daisuke, Miyahara Ryoji, Ishigami Masatoshi, Hirooka Yoshiki, Fujishiro Mitsuhiro
WORLD JOURNAL OF GASTROENTEROLOGY Vol. 26 ( 10 ) page： 1056 - 1066 2020.3
Favorable radiological antitumor response at 2 weeks after starting lenvatinib for patients with advanced hepatocellular carcinoma
Kuzuya Teiji, Ishigami Masatoshi, Ito Takanori, Ishizu Yoji, Honda Takashi, Ishikawa Tetsuya, Fujishiro Mitsuhiro
HEPATOLOGY RESEARCH Vol. 50 ( 3 ) page： 374 - 381 2020.3
Relationship Between Adverse Events and Microbiomes in Advanced Hepatocellular Carcinoma Patients Treated With Sorafenib
Yamamoto Kenta, Kuzuya Teiji, Honda Takashi, Ito Takanori, Ishizu Yoji, Nakamura Masanao, Miyahara Ryoji, Kawashima Hiroki, Ishigami Masatoshi, Fujishiro Mitsuhiro
ANTICANCER RESEARCH Vol. 40 ( 2 ) page： 665 - 676 2020.2
Usefulness of Endoscopic Ultrasound Elastography Combined With the Strain Ratio in the Estimation of Treatment Effect in Autoimmune Pancreatitis
Ishikawa Takuya, Kawashima Hiroki, Ohno Eizaburo, Tanaka Hiroyuki, Maeda Keiko, Sawada Tsunaki, Yamamura Takeshi, Furukawa Kazuhiro, Nakamura Masanao, Miyahara Ryoji, Ishigami Masatoshi, Fujishiro Mitsuhiro
PANCREAS Vol. 49 ( 2 ) page： E21 - E22 2020.2
Dipeptidyl peptidase-4 inhibition prevents nonalcoholic steatohepatitis-associated liver fibrosis and tumor development in mice independently of its anti-diabetic effects
Kawakubo Mitsuhiro, Tanaka Miyako, Ochi Kozue, Watanabe Akiko, Saka-Tanaka Marie, Kanamori Yohei, Yoshioka Naoki, Yamashita Satoko, Goto Moritaka, Itoh Michiko, Shirakawa Ibuki, Kanai Sayaka, Suzuki Hiromi, Sawada Makoto, Ito Ayaka, Ishigami Masatoshi, Fujishiro Mitsuhiro, Arima Hiroshi, Ogawa Yoshihiro, Suganami Takayoshi
SCIENTIFIC REPORTS Vol. 10 ( 1 ) page： 983 2020.1
Effect of weight change and lifestyle modifications on the development or remission of nonalcoholic fatty liver disease: sex-specific analysis
Yoshioka Naoki, Ishigami Masatoshi, Watanabe Yasuko, Sumi Hajime, Doisaki Masao, Yamaguchi Takeo, Ito Takanori, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Ishikawa Tetsuya, Haruta Jun-ichi, Fujishiro Mitsuhiro
SCIENTIFIC REPORTS Vol. 10 ( 1 ) page： 481 2020.1
Rapid increase of platelet counts during antiviral therapy in patients with hepatitis C virus infection
Ishizu Yoji, Ishigami Masatoshi, Hayashi Kazuhiko, Honda Takashi, Kuzuya Teiji, Ito Takanori, Fujishiro Mitsuhiro
HEPATOLOGY RESEARCH Vol. 50 ( 1 ) page： 47 - 56 2020.1
A Prospective Study of Factors Associated with Abdominal Pain in Patients during Unsedated Colonoscopy Using a Magnifying Endoscope
Suzuki Hiroto, Nakamura Masanao, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Takuya, Furukawa Kazuhiro, Ohno Eizaburo, Honda Takashi, Kawashima Hiroki, Ishigami Masatoshi, Fujishiro Mitsuhiro
INTERNAL MEDICINE Vol. 59 ( 15 ) page： 1795 - 1801 2020
Refractory Ulcerative Colitis Improved by Scheduled Combination Therapy of Vedolizumab and Granulocyte and Monocyte Adsorptive Apheresis
Nakamura Masanao, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Eri, Ohashi Ayako, Kajikawa Go, Furukawa Kazuhiro, Ohno Eizaburo, Honda Takashi, Kawashima Hiroki, Ishigami Masatoshi, Fujishiro Mitsuhiro
INTERNAL MEDICINE Vol. 59 ( 23 ) page： 3009 - 3014 2020
Sarcopenia impairs health-related quality of life in cirrhotic patients
Ando Yusuke, Ishigami Masatoshi, Ito Takanori, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Ishikawa Tetsuya, Fujishiro Mitsuhiro
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY Vol. 31 ( 12 ) page： 1550 - 1556 2019.12
CHANGES OF MICROBIOTA AFTER HEPATITIS C VIRUS ERADICATION
Honda Takashi, Ishigami Masatoshi, Yamamoto Kenta, Ito Takanori, Ishizu Yoji, Kuzuya Teiji, Fujishiro Mitsuhiro
HEPATOLOGY Vol. 70 page： 1160A - 1161A 2019.10
DO HEPATOLOGISTS FOLLOW-UP LOW REPLICATIVE HEPATITIS B VIRUS INACTIVE CARRIERS EFFECTIVELY? A MULTI-CENTER STUDY WITH 2,640 HBV PATIENTS IDENTIFIED AT THEIR INITIAL VISITS
Matono Tomomitsu, Isomoto Hajime, Inoue Takako, Tanaka Yasuhito, Ishigami Masatoshi, Suetsugu Atsushi, Enomoto Masaru, Sato Syuuichi, Sakai Akito, Hidaka Isao, Ogawa Koji, Inoue Jun, Kondo Yasuteru, Ide Tatsuya, Kakizaki Satoru, Kobayashi Yoshimasa, Genda Takuya, Korenaga Masaaki
HEPATOLOGY Vol. 70 page： 588A - 588A 2019.10
Increased hardness of the underlying pancreas correlates with the presence of intraductal papillary-mucinous neoplasm in a limited number of cases
Koya Toshinari, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Ishigami Masatoshi, Hashimoto Senju, Goto Hidemi, Hirooka Yoshiki
JOURNAL OF MEDICAL ULTRASONICS Vol. 46 ( 4 ) page： 441 - 447 2019.10
INDICATION FOR HCC TREATMENT IN RECENT ERA-PROPOSAL OF THE NEW PRIORITY FOR LIVER TRANSPLANTATION IN PATIENTS WITH HCC
Ishigami Masatoshi, Honda Takashi, Kuzuya Teiji, Ishizu Yoji, Ito Takanori, Fujishiro Mitsuhiro
HEPATOLOGY Vol. 70 page： 543A - 544A 2019.10
NON-INVASIVE SCREENING FOR DETECTING ESOPHAGOGASTRIC VARICES IN CHILDREN WITH BILIARY ATRESIA
Yokoyama Shinya, Ishigami Masatoshi, Honda Takashi, Kuzuya Teiji, Ishizu Yoji, Ito Takanori, Shirota Chiyoe, Uchida Hiroo, Fujishiro Mitsuhiro
HEPATOLOGY Vol. 70 page： 200A - 200A 2019.10
Spleen stiffness by 2-D shear wave elastography is the most accurate predictor of high-risk esophagogastric varices in children with biliary atresia
Yokoyama Shinya, Ishigami Masatoshi, Honda Takashi, Kuzuya Teiji, Ishizu Yoji, Ito Takanori, Hirooka Yoshiki, Tanaka Yujiro, Tainaka Takahisa, Shirota Chiyoe, Chiba Kosuke, Uchida Hiroo, Fujishiro Mitsuhiro
HEPATOLOGY RESEARCH Vol. 49 ( 10 ) page： 1162 - 1168 2019.10
UTILITY OF THE ALBUMIN-BILIRUBIN SCORE FOR PREDICTING PROGNOSIS IN JAPANESE PATIENTS WITH PRIMARY BILIARY CHOLANGITIS: AN ANALYSIS USING TIME-DEPENDENT RECEIVER OPERATING CHARACTERISTICS
Ito Takanori, Ishigami Masatoshi, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Yasuda Satoshi, Toyoda Hidenori, Kumada Takashi, Fujishiro Mitsuhiro
HEPATOLOGY Vol. 70 page： 789A - 790A 2019.10
Antifibrotic Effects of 1,25(OH)(2)D-3 on Nonalcoholic Steatohepatitis in Female Mice
Ma Lingyun, Ishigami Masatoshi, Honda Takashi, Yokoyama Shinya, Yamamoto Kenta, Ishizu Yoji, Kuzuya Teiji, Hayashi Kazuhiko, Hirooka Yoshiki, Goto Hidemi
DIGESTIVE DISEASES AND SCIENCES Vol. 64 ( 9 ) page： 2581 - 2590 2019.9
Clinical characteristics and outcomes of candidates for second-line therapy, including regorafenib and ramucirumab, for advanced hepatocellular carcinoma after sorafenib treatment
Kuzuya Teiji, Ishigami Masatoshi, Ito Takanori, Ishizu Yoji, Honda Takashi, Ishikawa Tetsuya, Hirooka Yoshiki, Fujishiro Mitsuhiro
HEPATOLOGY RESEARCH Vol. 49 ( 9 ) page： 1054 - 1065 2019.9
The relationship between portal hypertension and the microbiome
Yamamoto K., Honda T., Hattori S., Pu L. Zorron Cheng Tao, Ito T., Yamamura T., Ishizu Y., Kuzuya T., Ishigami M., Fujishiro M.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 34 page： 106 - 107 2019.9
THE PROPAGATION DISPLAY METHOD IMPROVES THE REPRODUCIBILITY OF PANCREATIC SHEAR WAVE ELASTOGRAPHY
Hashizume Kiyotaka, Hirooka Yoshiki, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Kawai Manabu, Suhara Hiroki, Takeyama Tomoaki, Koya Toshinari, Tanaka Hiroyuki, Sakai Daisuke, Yamamura Takeshi, Furukawa Kazuhiro, Funasaka Kohei, Nakamura Masanao, Miyahara Ryoji, Watanabe Osamu, Ishigami Masatoshi, Kuwahara Takamichi, Hashimoto Senju, Goto Hidemi
ULTRASOUND IN MEDICINE AND BIOLOGY Vol. 45 ( 8 ) page： 2242 - 2247 2019.8
Comparison of 8-and 10-mm diameter fully covered self-expandable metal stents: A multicenter prospective study in patients with distal malignant biliary obstruction
Kawashima Hiroki, Hashimoto Senju, Ohno Eizaburo, Ishikawa Takuya, Morishima Tomomasa, Matsubara Hiroshi, Sugimoto Hiroyuki, Nonogaki Koji, Kanamori Akira, Hara Kazuo, Kuwahara Takamichi, Nakamura Masanao, Miyahara Ryoji, Ishigami Masatoshi, Ando Masahiko, Hirooka Yoshiki
DIGESTIVE ENDOSCOPY Vol. 31 ( 4 ) page： 439 - 447 2019.7
Efficacy and safety of glecaprevir and pibrentasvir treatment for 8 or 12weeks in patients with recurrent hepatitis C after liver transplantation: a Japanese multicenter experience
Ueda Yoshihide, Kobayashi Tsuyoshi, Ikegami Toru, Miuma Satoshi, Mizuno Shugo, Akamatsu Nobuhisa, Takaki Akinobu, Ishigami Masatoshi, Takatsuki Mitsuhisa, Sugawara Yasuhiko, Maehara Yoshihiko, Uemoto Shinji, Seno Hiroshi
JOURNAL OF GASTROENTEROLOGY Vol. 54 ( 7 ) page： 660 - 666 2019.7
Association between core mutations and annual decline rate of HBVDNA and HBsAg in chronic hepatitis B patients treated with nucleoside analogue
Honda Takashi, Ishigami Masatoshi, Ito Takanori, Ishizu Yoji, Kuzuya Teiji, Fujishiro Mitsuhiro
JOURNAL OF HEPATOLOGY Vol. 70 ( 1 ) page： E258 - E258 2019.4
Association between gut microbiota and hepatocellular carcinoma in patients with chronic liver disease
Honda Takashi, Ishigami Masatoshi, Yamamoto Kenta, Ito Takanori, Ishizu Yoji, Kuzuya Teiji, Fujishiro Mitsuhiro
JOURNAL OF HEPATOLOGY Vol. 70 ( 1 ) page： E512 - E513 2019.4
Serum Zinc levels as a prognostic factor for extra-hepatic carcinogenesis in Japanese patients with non-alcoholic liver disease
Ito Takanori, Ishigami Masatoshi, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Fujishiro Mitsuhiro
JOURNAL OF HEPATOLOGY Vol. 70 ( 1 ) page： E298 - E298 2019.4
The optimal cut-off points of FIB-4 index for predicting the incidences of HCC and extra-hepatic malignancies in biopsyproven Japanese NAFLD patients
Ito Takanori, Ishigami Masatoshi, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Fujishiro Mitsuhiro
JOURNAL OF HEPATOLOGY Vol. 70 ( 1 ) page： E775 - E775 2019.4
The early clinical response at 2 weeks of lenvatinib therapy for patients with advanced HCC
Kuzuya Teiji, Ishigami Masatoshi, Ito Takanori, Ishizu Yoji, Honda Takashi, Fujishiro Mitsuhiro
JOURNAL OF HEPATOLOGY Vol. 70 ( 1 ) page： E611 - E611 2019.4
Complete response by vitamin K2 analog monotherapy in sorafenib-failure advanced hepatocellular carcinoma: A case report
Kuzuya Teiji, Ishigami Masatoshi, Ishizu Yoji, Honda Takashi, Hayashi Kazuhiko, Ishikawa Tetsuya, Hirooka Yoshiki, Goto Hidemi
HEPATOLOGY RESEARCH Vol. 49 ( 3 ) page： 360 - 364 2019.3
Influence of proton pump inhibitors on microbiota in chronic liver disease patients
Yamamoto Kenta, Ishigami Masatoshi, Honda Takashi, Takeyama Tomoaki, Ito Takanori, Ishizu Yoji, Kuzuya Teiji, Hayashi Kazuhiko, Goto Hidemi, Hirooka Yoshiki
HEPATOLOGY INTERNATIONAL Vol. 13 ( 2 ) page： 234 - 244 2019.3
Successful treatment of esophageal bleeding due to rupture of major aortopulmonary collateral arteries by transcatheter arterial embolization
Ito Takanori, Ishigami Masatoshi, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Matsushima Masaya, Kato Taichi, Hirooka Yoshiki
CLINICAL JOURNAL OF GASTROENTEROLOGY Vol. 12 ( 1 ) page： 20 - 24 2019.2
Utility and limitations of noninvasive fibrosis markers for predicting prognosis in biopsy-proven Japanese non-alcoholic fatty liver disease patients
Ito Takanori, Ishigami Masatoshi, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Hayashi Kazuhiko, Nishimura Daisaku, Toyoda Hidenori, Kumada Takashi, Goto Hidemi, Hirooka Yoshiki
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 34 ( 1 ) page： 207 - 214 2019.1
Transabdominal ultrasound elastography of the esophagogastric junction predicts reflux esophagitis
Suhara Hiroki, Hirooka Yoshiki, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Nakamura Masanao, Miyahara Ryoji, Ishigami Masatoshi, Hashimoto Senju, Goto Hidemi
JOURNAL OF MEDICAL ULTRASONICS Vol. 46 ( 1 ) page： 99 - 104 2019.1
Clinical Impact of EUS-Guided Fine Needle Biopsy Using a Novel Franseen Needle for Histological Assessment of Pancreatic Diseases
Ishikawa Takuya, Kawashima Hiroki, Ohno Eizaburo, Tanaka Hiroyuki, Sakai Daisuke, Iida Tadashi, Nishio Ryo, Yamamura Takeshi, Furukawa Kazuhiro, Nakamura Masanao, Miyahara Ryoji, Hashimoto Senju, Ishigami Masatoshi, Hirooka Yoshiki
CANADIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 2019 page： 8581743 2019
Successful Treatment of Hepatocellular Carcinoma with Regorafenib after Sorafenib-induced Hypersensitivity
Yoshioka Naoki, Kuzuya Teiji, Ito Takanori, Ishizu Yoji, Honda Takashi, Ishikawa Tetsuya, Ishigami Masatoshi, Fujishiro Mitsuhiro
INTERNAL MEDICINE Vol. 58 ( 19 ) page： 2803 - 2808 2019
The Prevalence of Mixed Hepatitis C Virus Genotype Infection and Its Effect on the Response to Direct-Acting Antivirals Therapy
Hayashi Kazuhiko, Tachi Kosuke, Shimizu Yuko, Nagano Kenichi, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Ishigami Masatoshi, Hirooka Yoshiki, Hattori Masashi, Goto Hidemi
INTERVIROLOGY Vol. 62 ( 1 ) page： 23 - 29 2019
Late relapse of hepatitis C virus in patients with sustained virological response after daclatasvir and asunaprevir therapy
Hayashi Kazuhiko, Ishigami Masatoshi, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Hirooka Yoshiki, Toyoda Hidenori, Kumada Takashi, Hattori Masashi, Katano Yoshiaki, Goto Hidemi
JOURNAL OF VIRAL HEPATITIS Vol. 25 ( 12 ) page： 1446 - 1451 2018.12
Utility of contrast-enhanced ultrasonography with perflubutane in evaluating indications for diagnostic percutaneous tumor biopsy in a case of hepatic sclerosed hemangioma
Ando Yusuke, Ishigami Masatoshi, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Hirooka Yoshiki
CLINICAL JOURNAL OF GASTROENTEROLOGY Vol. 11 ( 6 ) page： 514 - 520 2018.12
Substitutions in interferon sensitivity-determining region and hepatocarcinogenesis after hepatitis C virus eradication
Yasuda Satoshi, Ishigami Masatoshi, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Hayashi Kazuhiko, Toyoda Hidenori, Kumada Takashi, Hirooka Yoshiki, Goto Hidemi
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 33 ( 11 ) page： 1904 - 1911 2018.11
Association between Core Mutations Induced By Interferon Therapy and Annual Decline Rate of Hbvdna in Chronic Hepatitis B Patients
Honda Takashi, Ishigami Masatoshi, Ito Takanori, Ishizu Yoji, Kuzuya Teiji, Hirooka Yoshiki
HEPATOLOGY Vol. 68 page： 1233A - 1234A 2018.10
Comparison of Gut Microbiota and Predicted Functional Metagenome in Hepatitis C Patients with and without Advanced Fibrosis Categorized By FIB4-Index
Yamamoto Kenta, Ishigami Masatoshi, Ito Takanori, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Hirooka Yoshiki
HEPATOLOGY Vol. 68 page： 590A - 590A 2018.10
Interferon-Free Antiviral Therapy Rapidly Improves Thrombocytopenia in Patients with Advanced Chronic Hepatitis C
Ishizu Yoji, Ishigami Masatoshi, Ito Takanori, Kuzuya Teiji, Honda Takashi, Hirooka Yoshiki
HEPATOLOGY Vol. 68 page： 1157A - 1158A 2018.10
Late Relapse and Molecular Analysis of Hepatitis C Virus in Patients with Sustained Virological Response By All Oral Direct Acting Antivirals Therapy
Hayashi Kazuhiko, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Ishigami Masatoshi, Shimizu Yuko, Tachi Kousuke, Goto Hidemi
HEPATOLOGY Vol. 68 page： 927A - 927A 2018.10
Skeletal muscle fat deposition is associated with hepatocellular carcinoma development in patients with chronic liver disease
Tachi Yoshihiko, Kozuka Akihiro, Hirai Takanori, Kojima Yuko, Ishizu Yoji, Honda Takashi, Kuzuya Teiji, Hayashi Kazuhiko, Ishigami Masatoshi, Goto Hidemi
NUTRITION Vol. 54 page： 83 - 88 2018.10
Predictive ability of shear wave elastography for pruritus in chronic hepatitis C patients with sustained virological response
Tachi Yoshihiko, Hirai Takanori, Kojima Yuko, Ishizu Yoji, Honda Takashi, Kuzuya Teiji, Hayashi Kazuhiko, Ishigami Masatoshi, Goto Hidemi, Katano Yoshiaki
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY Vol. 30 ( 9 ) page： 1066 - 1072 2018.9
Effectiveness of a modified 6-Fr endoscopic nasobiliary drainage catheter for patients with preoperative perihilar cholangiocarcinoma
Kawashima Hiroki, Hirooka Yoshiki, Ohno Eizaburo, Ishikawa Takuya, Miyahara Ryoji, Watanabe Osamu, Hayashi Kazuhiko, Ishigami Masatoshi, Hashimoto Senju, Ebata Tomoki, Nagino Masato, Goto Hidemi
ENDOSCOPY INTERNATIONAL OPEN Vol. 6 ( 8 ) page： E1020 - E1030 2018.8
Objective evaluation of blood flow in the small-intestinal villous: quantification of findings from dynamic endoscopy with concomitant narrow-band imaging
Takeyama Tomoaki, Hirooka Yoshiki, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Yamamura Takeshi, Furukawa Kazuhiro, Funasaka Kohei, Nakamura Masanao, Miyahara Ryoji, Ishigami Masatoshi, Goto Hidemi
ENDOSCOPY INTERNATIONAL OPEN Vol. 6 ( 8 ) page： E941 - E949 2018.8
Diagnostic Usefulness of APRI and FIB-4 for the Prediction of Liver Fibrosis After Liver Transplantation in Patients Infected with Hepatitis C Virus
Imai H., Kamei H., Onishi Y., Ishizu Y., Ishigami M., Goto H., Ogura Y.
TRANSPLANTATION PROCEEDINGS Vol. 50 ( 5 ) page： 1431 - 1436 2018.6
Daclatasvir and asunaprevir treatment in patients infected by genotype 1b of hepatitis C virus with no or subtle resistant associated substitutions (RAS) in NS5A-Y93
Ishigami Masatoshi, Hayashi Kazuhiko, Honda Takashi, Kuzuya Teiji, Ishizu Yoji, Ishikawa Tetsuya, Nakano Isao, Urano Fumihiro, Kumada Takashi, Yoshioka Kentaro, Hirooka Yoshiki, Goto Hidemi
JOURNAL OF MEDICAL VIROLOGY Vol. 90 ( 4 ) page： 736 - 744 2018.4
Naturally occurring drug resitance substitutions in the NS5A and NS5B regions in Hepatitis C virus genotype 2 and response to sofosbuvir plus ribavirin therapy
Hayashi K., Ishigami M., Ishizu Y., Kazuya T., Honda T., Hirooka Y., Goto H.
JOURNAL OF HEPATOLOGY Vol. 68 page： S297 - S297 2018.4
Secreted ectodomain of SIGLEC-9 and MCP-1 ameliorate acute liver failure in rats by altering bone marrow macrophage polarity
Ito T., Ishigami M., Yamamoto A., Ishizu Y., Kazuya T., Honda T., Hayashi K., Ishikawa T., Hirooka Y., Goto H.
JOURNAL OF HEPATOLOGY Vol. 68 page： S614 - S614 2018.4
Utility and limitation of non-invasive fibrosis markers for predicting the prognosis in biopsy-proven Japanese NAFLD patients
Ito T., Ishigami M., Ishizu Y., Kazuya T., Honda T., Hayashi K., Ishikawa T., Hirooka Y., Goto H.
JOURNAL OF HEPATOLOGY Vol. 68 page： S561 - S561 2018.4
Cumulative incidence and risk factors for the development of hepatocellular carcinoma in patients with chronic hepatitis B who achieved sustained disappearance of viremia by nucleos(t)ide analog treatment
Ando Yusuke, Ishigami Masatoshi, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Hayashi Kazuhiko, Ishikawa Tetsuya, Nakano Isao, Hirooka Yoshiki, Goto Hidemi
HEPATOLOGY RESEARCH Vol. 48 ( 3 ) page： E240-E251 2018.2
Comparison of direct sequencing and Invader assay for Y93H mutation and response to interferon-free therapy in hepatitis C virus genotype 1b
Hayashi Kazuhiko, Ishigami Masatoshi, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Kawashima Hiroki, Ishikawa Tetsuya, Tachi Yoshihiko, Hattori Masashi, Katano Yoshiaki, Goto Hidemi, Hirooka Yoshiki
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 33 ( 1 ) page： 249-255 2018.1
Functional Correlation Between the Pancreas and the Small Intestine in Humans: The First Evaluation Using a Newly Developed Enteroscopy
Hayashi Daijuro, Hirooka Yoshiki, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Kuwahara Takamichi, Kawai Manabu, Yamamura Takeshi, Furukawa Kazuhiro, Funasaka Kohei, Nakamura Masanao, Miyahara Ryoji, Watanabe Osamu, Ishigami Masatoshi, Hashimoto Senju, Goto Hidemi
PANCREAS Vol. 47 ( 5 ) page： 601 - 608 2018
Prognostic Factors Associated with Postprogression Survival in Advanced Hepatocellular Carcinoma Patients Treated with Sorafenib Not Eligible for Second-Line Regorafenib Treatment
Kuzuya Teiji, Ishigami Masatoshi, Ishizu Yoji, Honda Takashi, Hayashi Kazuhiko, Ishikawa Tetsuya, Nakano Isao, Hirooka Yoshiki, Goto Hidemi
ONCOLOGY Vol. 95 ( 2 ) page： 91 - 99 2018
Pseudomembranous Invasive Tracheobronchial Aspergillosis with Fulminant Hepatitis and Hemophagocytic Syndrome
Majima Suguru, Okachi Shotaro, Asano Motoyo, Wakahara Keiko, Hashimoto Naozumi, Sato Mitsuo, Ishigami Masatoshi, Hasegawa Yoshinori
INTERNAL MEDICINE Vol. 57 ( 16 ) page： 2371 - 2375 2018
Daclatasvir and asunaprevir treatment in patients with severe liver fibrosis by HCV genotype 1b infection: Real world data. Reviewed
. Ishigami M, Hayashi K, Honda T, Kuzuya T, Ishizu Y, Ishikawa T, Nakano I, Urano F, Kumada T, Yoshioka K, Goto H, Hirooka Y.
J Gastroenterol Hepatol Vol. 32 page： 1879-1886 2017.11
Daclatasvir and asunaprevir treatment in patients with severe liver fibrosis by hepatitis C virus genotype 1b infection: Real-world data
Ishigami Masatoshi, Hayashi Kazuhiko, Honda Takashi, Kuzuya Teiji, Ishizu Yoji, Ishikawa Tetsuya, Nakano Isao, Urano Fumihiro, Kumada Takashi, Yoshioka Kentaro, Goto Hidemi, Hirooka Yoshiki
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 32 ( 11 ) page： 1879-1886 2017.11
Low skeletal muscle mass predicts early mortality in cirrhotic patients with acute variceal bleeding
Ishizu Yoji, Ishigami Masatoshi, Kuzuya Teiji, Honda Takashi, Hayashi Kazuhiko, Ishikawa Tetsuya, Hirooka Yoshiki, Goto Hidemi
NUTRITION Vol. 42 page： 87-91 2017.10
Liver stiffness measurement predicts hepatocellular carcinoma development in patients treated with direct-acting antivirals
Tachi Yoshihiko, Hirai Takanori, Kojima Yuko, Ishizu Yoji, Honda Takashi, Kuzuya Teiji, Hayashi Kazuhiko, Ishigami Masatoshi, Goto Hidemi
JGH OPEN Vol. 1 ( 1 ) page： 44 - 49 2017.9
Multifaceted therapeutic benefits of factors derived from stem cells from human exfoliated deciduous teeth for acute liver failure in rats
Matsushita Yoshihiro, Ishigami Masatoshi, Matsubara Kohki, Kondo Megumi, Wakayama Hirotaka, Goto Hidemi, Ueda Minoru, Yamamoto Akihito
JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE Vol. 11 ( 6 ) page： 1888-1896 2017.6
Core I97L mutation in conjunction with P79Q is associated with persistent low HBV DNA and HBs antigen clearance in patients with chronic hepatitis B
Honda T., Ishigami M., Ishizu Y., Kuzuya T., Hayashi K., Ishikawa T., Murakami Y., Iwadate M., Umeyama H., Toyoda H., Kumada T., Katano Y., Goto H., Hirooka Y.
CLINICAL MICROBIOLOGY AND INFECTION Vol. 23 ( 6 ) 2017.6
Real World Data of Daclatasvir and Asunaprevir Combination Therapy for HCV Genotype 1b Infection in Patients With Renal Dysfunction
Ishigami Masatoshi, Hayashi Kazuhiko, Honda Takashi, Kuzuya Teiji, Ishizu Yoji, Ishikawa Tetsuya, Nakano Isao, Urano Fumihiro, Kumada Takashi, Yoshioka Kentaro, Goto Hidemi, Hirooka Yoshiki
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY Vol. 15 ( 5 ) page： 787 - 788 2017.5
Branched-chain amino acids alleviate hepatic steatosis and liver injury in choline-deficient high-fat diet induced NASH mice
Honda Takashi, Ishigami Masatoshi, Luo Fangqiong, Lingyun Ma, Ishizu Yoji, Kuzuya Teiji, Hayashi Kazuhiko, Nakano Isao, Ishikawa Tetsuya, Feng Guo-Gang, Katano Yoshiaki, Kohama Tomoya, Kitaura Yasuyuki, Shimomura Yoshiharu, Goto Hidemi, Hirooka Yoshiki
METABOLISM-CLINICAL AND EXPERIMENTAL Vol. 69 page： 177-187 2017.4
Secreted Ectodomain of SIGLEC-9 and MCP-1 Synergistically Improve Acute Liver Failure in Rats by Altering Macrophage Polarity
Ito Takanori, Ishigami Masatoshi, Matsushita Yoshihiro, Hirata Marina, Matsubara Kohki, Ishikawa Tetsuya, Hibi Hideharu, Ueda Minoru, Hirooka Yoshiki, Goto Hidemi, Yamamoto Akihito
SCIENTIFIC REPORTS Vol. 7 page： 44043 2017.3
Immunomodulatory Effects of Adipose Tissue-Derived Stem Cells on Concanavalin A-Induced Acute Liver Injury in Mice.
Yoshizumi Y, Yukawa H, Iwaki R, Fujinaka S, Kanou A, Kanou Y, Yamada T, Nakagawa S, Ohara T, Nakagiri K, Ogihara Y, Tsutsui Y, Hayashi Y, Ishigami M, Baba Y, Ishikawa T
Cell medicine Vol. 9 ( 1-2 ) page： 21 - 33 2017.1
Phenotypes and Chronic Organ Damage May Be Different among Siblings with Wilson's Disease
Yahata Shinsuke, Yung Seitetsu, Mandai Mari, Nagahara Takakazu, Kuzume Daisaku, Sakaeda Hiroshi, Wakusawa Shinya, Kato Ayako, Tatsumi Yasuaki, Kato Koichi, Hayashi Hisao, Isaji Ryohei, Sasaki Yoji, Yano Motoyoshi, Hayashi Kazuhiko, Ishigami Masatoshi, Goto Hidemi
JOURNAL OF CLINICAL AND TRANSLATIONAL HEPATOLOGY Vol. 5 ( 1 ) page： 27 - 30 2017
急性肝不全モデル動物における歯髄由来幹細胞の効果-肝臓における炎症と再生の相関
2015.4 - 2018.3
科学研究費補助金 基盤研究(C)
Authorship：Principal investigator
免疫学的劇症肝炎モデルマウスにおける新たな細胞治療の基礎的検討
2012.4 - 2015.3
科学研究費補助金 基盤研究(C)
Authorship：Principal investigator
炎症・ウイルス感染環境下での肝構成細胞の免疫・代謝応答の解析
2011.4 - 2014.3
科学研究費補助金 基盤研究(C)
石川 哲也
Authorship：Coinvestigator(s)
Effect of MCP-1 and sSiglec9 in the animal models of acute liver failure
Grant number：18K07936 2018.4 - 2022.3
Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)
Authorship：Principal investigator
Grant amount：\4420000 （ Direct Cost: \3400000 、 Indirect Cost：\1020000 ）
Gut microbiota and therapeutic intervention in non-B,non-C hepatocellular carcinoma
Grant number：17K09418 2017.4 - 2020.3
Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)
HONDA TAKASHI
Authorship：Coinvestigator(s)
In the mouse model of liver cancer, network analysis showed the bacteria in the gut have unique interaction with each other. We identified some different types of bacteria have been associated with tumorigenesis and fibrogenesis.
Patients with hepatocellular carcinoma (HCC) had increased genus Actiomyces compared to those without HCC. In the patients with non-B,non-C HCC, genus Veillonella increased compared to those without HCC. There is a possibility that there is a difference in gut microbiota such as oral indigenous bacteria between patients with and without HCC.
Effect of Stem Cells derived from Human Exfoliated Decidious Teeth in animal model of acute liver failure-correlation between inflammation and regeneration in liver
Grant number：15K08996 2015.4 - 2018.3
ISHIGAMI MASATOSHI
Authorship：Principal investigator
Grant amount：\4810000 （ Direct Cost: \3700000 、 Indirect Cost：\1110000 ）
In acute liver failure, liver regeneration is essential to be cured, however, there are no effective drugs to use for the intervention to the liver regeneration in clinical practice.
We investigated the culture medium of stem cells derived from human exfoliated dedicious teeth (SHED-CM) in animal model of acute liver failure, and showed higher efficacy compared with other stem cells. And as the abundant humoral factors in SHED-CM, we found MCP-1, which is well-known chemoattractant of monocytes-macrophages, and secreted domain of Siglec-9, which is the key factors for transition of pro- to antiinflammatory phase of macrophages, and we also found high efficacy of these two factors for improving survival of animals, supression of the inflammation, and promotion of the hepatocyte regeneration.
These two factors might become hopeful tools for the newly developement of the drugs for acute liver failure.
