Predictive performance of Shock Index for postpartum hemorrhage during cesarean delivery. Reviewed

Mizutani H, Ushida T, Ozeki K, Tano S, Iitani Y, Imai K, Nishiwaki K, Kajiyama H, Kotani T

International journal of obstetric anesthesia     page： 103957   2023.11

Long-term effects of gestational weight gain on mortality Invited

Kotani, T; Tano, S

LANCET   Vol. 402 ( 10415 ) page： 1809 - 1811   2023.11

Antenatal corticosteroids and outcomes of small for gestational age infants born at 24-31 gestational weeks: a population-based propensity score matching analysis Reviewed

Ushida, T; Nakatochi, M; Kobayashi, Y; Nakamura, N; Fuma, K; Iitani, Y; Imai, K; Sato, Y; Hayakawa, M; Kajiyama, H; Kotani, T; Japan, NRNO

ARCHIVES OF GYNECOLOGY AND OBSTETRICS   Vol. 308 ( 5 ) page： 1463 - 1471   2023.11

Interleukin-17A stimulation induces alterations in Microglial microRNA expression profiles Reviewed

Iitani, Y; Miki, R; Imai, K; Fuma, K; Ushida, T; Tano, S; Yoshida, K; Yokoi, A; Kajiyama, H; Kotani, T

PEDIATRIC RESEARCH   Vol. 95 ( 1 ) page： 167 - 173   2023.9

Comparison of the efficacy between controlled-release dinoprostone delivery system (PROPESS) and Cook's double balloon catheter plus oxytocin: A retrospective single-center study in Japan Reviewed

Imai, K; Nozaki, Y; Ushida, T; Tano, S; Kajiyama, H; Kotani, T

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH   Vol. 49 ( 9 ) page： 2317 - 2323   2023.9

The balance between fetal oxytocin and placental leucine aminopeptidase (P-LAP) controls human uterine contraction around labor onset Reviewed

Yoshihara, M; Mizutani, S; Matsumoto, K; Kato, Y; Masuo, Y; Harumasa, A; Iyoshi, S; Tano, S; Mizutani, H; Kotani, T; Mizutani, E; Shibata, K; Kajiyama, H

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY-X   Vol. 19   page： 100210   2023.9

Altered offspring neurodevelopment in an L-NAME-induced preeclampsia rat model Reviewed

Nakamura, N; Ushida, T; Onoda, A; Ueda, K; Miura, R; Suzuki, T; Katsuki, S; Mizutani, H; Yoshida, K; Tano, S; Iitani, Y; Imai, K; Hayakawa, M; Kajiyama, H; Sato, Y; Kotani, T

FRONTIERS IN PEDIATRICS   Vol. 11   page： 1168173   2023.7

Evaluating glucose variability through OGTT in early pregnancy and its association with hypertensive disorders of pregnancy in non-diabetic pregnancies: a large-scale multi-center retrospective study Reviewed

Tano, S; Kotani, T; Ushida, T; Yoshihara, M; Imai, K; Nakamura, N; Iitani, Y; Moriyama, Y; Emoto, R; Kato, S; Yoshida, S; Yamashita, M; Kishigami, Y; Oguchi, H; Matsui, S; Kajiyama, H

DIABETOLOGY & METABOLIC SYNDROME   Vol. 15 ( 1 ) page： 123   2023.6

Intrauterine exposure to chorioamnionitis and neuroanatomical alterations at term-equivalent age in preterm infants Reviewed

Nosaka, R; Ushida, T; Kidokoro, H; Kawaguchi, M; Shiraki, A; Iitani, Y; Imai, K; Nakamura, N; Sato, Y; Hayakawa, M; Natsume, J; Kajiyama, H; Kotani, T

ARCHIVES OF GYNECOLOGY AND OBSTETRICS     2023.5

Antenatal corticosteroids-to-delivery interval associates cord blood S100B levels. Reviewed

The journal of obstetrics and gynaecology research   Vol. 49 ( 4 ) page： 1129 - 1136   2023.4

Clinical significances of Bishop score and vaginal bleeding to controlled-release dinoprostone delivery system (PROPESS) efficacy for cervical ripening: A retrospective single-center study in Japan. Reviewed

The journal of obstetrics and gynaecology research   Vol. 49 ( 4 ) page： 1154 - 1160   2023.4

Trend changes in age-related body mass index gain after coronavirus disease 2019 pandemic in Japan: a multicenter retrospective cohort study. Reviewed

Reproductive biology and endocrinology : RB&E   Vol. 21 ( 1 ) page： 7   2023.1

Prenatal diagnosis of distal 13q deletion syndrome in a fetus with esophageal atresia: a case report and review of the literature. Reviewed

Journal of medical case reports   Vol. 16 ( 1 ) page： 481   2022.12

Aberrant inflammation in rat pregnancy leads to cardiometabolic alterations in their offspring and intrauterine growth restriction in the F2 generation Reviewed International coauthorship

Ushida, T; Cotechini, T; Protopapas, N; Atallah, A; Collyer, C; Toews, AJ; Macdonald-Goodfellow, SK; Tse, MY; Winn, LM; Pang, SC; Adams, MA; Othman, M; Kotani, T; Kajiyama, H; Graham, CH

JOURNAL OF DEVELOPMENTAL ORIGINS OF HEALTH AND DISEASE   Vol. 13 ( 6 ) page： 706 - 718   2022.12

A case of non-immune hydrops fetalis with maternal mirror syndrome diagnosed by trio-based exome sequencing: An autopsy case report and literature review. Reviewed

Molecular genetics and metabolism reports   Vol. 33   page： 100925   2022.12

Molecular hydrogen has a positive impact on pregnancy maintenance through enhancement of mitochondrial function and immunomodulatory effects on T cells Reviewed

Aoki, C; Imai, K; Mizutani, T; Sugiyama, D; Miki, R; Koya, Y; Kobayashi, T; Ushida, T; Iitani, Y; Nakamura, N; Owaki, T; Nishikawa, H; Toyokuni, S; Kajiyama, H; Kotani, T

LIFE SCIENCES   Vol. 308   page： 120955   2022.11

Optimal annual body mass index change for preventing spontaneous preterm birth in a subsequent pregnancy. Reviewed

Scientific reports   Vol. 12 ( 1 ) page： 17502   2022.10

5p deletion with congenital diaphragmatic hernia: a case report Reviewed

Kotani, T; Ushida, T; Nakamura, N; Imai, K; Iitani, Y; Tano, S; Iwagaki, S; Takahashi, Y; Ito, M; Hayakawa, M; Kajiyama, H

JOURNAL OF MEDICAL CASE REPORTS   Vol. 16 ( 1 ) page： 390   2022.10

Severe Congenital Diaphragmatic Hernia With Trisomy 9: A Case Report and Review of the Literature

Fuma, K; Kotani, T; Nakamura, N; Ushida, T; Kajiyama, H

CUREUS JOURNAL OF MEDICAL SCIENCE   Vol. 14 ( 8 ) page： e28395   2022.8

Impact of hypertensive disorders of pregnancy on respiratory outcomes in extremely and very preterm infants: A population-based study in Japan Reviewed

Ushida, T; Nakamura, N; Nakatochi, M; Kobayashi, Y; Sato, Y; Iitani, Y; Imai, K; Nakano-Kobayashi, T; Hayakawa, M; Kajiyama, H; Kotani, T

PREGNANCY HYPERTENSION-AN INTERNATIONAL JOURNAL OF WOMENS CARDIOVASCULAR HEALTH   Vol. 29   page： 54 - 60   2022.8

Reassessing the duration of each stage of labor and their relation to postpartum hemorrhage in the current Japanese population Reviewed

Ushida, T; Matsuo, S; Nakamura, N; Iitani, Y; Imai, K; Nakano-Kobayashi, T; Yoshida, S; Yamashita, M; Kajiyama, H; Kotani, T

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH   Vol. 48 ( 7 ) page： 1760 - 1767   2022.7

Machine learning prediction models for postpartum depression: A multicenter study in Japan Reviewed

Matsuo, S; Ushida, T; Emoto, R; Moriyama, Y; Iitani, Y; Nakamura, N; Imai, K; Nakano-Kobayashi, T; Yoshida, S; Yamashita, M; Matsui, S; Kajiyama, H; Kotani, T

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH   Vol. 48 ( 7 ) page： 1775 - 1785   2022.7

The Possible Effects of Zinc Supplementation on Postpartum Depression and Anemia Reviewed

Aoki, C; Imai, K; Owaki, T; Kobayashi-Nakano, T; Ushida, T; Iitani, Y; Nakamura, N; Kajiyama, H; Kotani, T

MEDICINA-LITHUANIA   Vol. 58 ( 6 )   2022.6

Intrauterine exposure to hypertensive disorders of pregnancy and postnatal growth in extremely and very preterm infants Reviewed

Ushida, T; Kotani, T; Nakatochi, M; Kobayashi, Y; Nakamura, N; Imai, K; Iitani, Y; Nakano-Kobayashi, T; Hayakawa, M; Kajiyama, H

PREGNANCY HYPERTENSION-AN INTERNATIONAL JOURNAL OF WOMENS CARDIOVASCULAR HEALTH   Vol. 28   page： 174 - 179   2022.6

Tadalafil treatment for fetuses with early-onset growth restriction: a protocol for a multicentre, randomised, placebo-controlled, double-blind phase II trial (TADAFER IIb) Reviewed

Maki, S; Tanaka, H; Takakura, S; Nii, M; Tanaka, K; Ogura, T; Kotera, M; Nishimura, Y; Tamaru, S; Ushida, T; Tanaka, Y; Kikuchi, N; Kinjo, T; Kawamura, H; Takano, M; Nakamura, K; Suga, S; Kasai, M; Yasui, O; Nagao, K; Maegawa, Y; Kotani, T; Endo, M; Yasuhi, I; Aoki, S; Aoki, Y; Yoshida, Y; Nakata, M; Sekizawa, A; Ikeda, T

BMJ OPEN   Vol. 12 ( 6 ) page： e054925   2022.6

Prevalence of common aneuploidy in twin pregnancies Reviewed

Konishi, A; Samura, O; Muromoto, J; Okamoto, Y; Takahashi, H; Kasai, Y; Ichikawa, M; Yamada, N; Kato, N; Sato, H; Hamada, H; Nakanami, N; Machi, M; Ichizuka, K; Sunami, R; Tanaka, T; Yonetani, N; Kamei, Y; Nagamatsu, T; Matsumoto, M; Tairaku, S; Fujiwara, A; Nakamura, H; Harada, T; Watanabe, T; Sasaki, S; Kawaguchi, S; Minami, S; Ogawa, M; Miura, K; Suzumori, N; Kojima, J; Kotani, T; Sasaki, R; Baba, T; Toyofuku, A; Endo, M; Takeshita, N; Taketani, T; Sase, M; Matsubara, K; Hayata, K; Hamada, Y; Egawa, M; Kakinuma, T; Matsushima, S; Kitagawa, M; Shiga, T; Kurashina, R; Hamada, H; Takagi, H; Kondo, A; Miharu, N; Yamashita, M; Horiya, M; Morimoto, K; Takahashi, K; Okamoto, A; Sekizawa, A; Sago, H

JOURNAL OF HUMAN GENETICS   Vol. 67 ( 5 ) page： 261 - 265   2022.5

Pregnancy Outcomes in Women with Thyroid Diseases Reviewed

Kotani, T; Imai, K; Ushida, T; Moriyama, Y; Nakano-Kobayashi, T; Osuka, S; Tsuda, H; Sumigama, S; Yamamoto, E; Kinoshita, F; Hirakawa, A; Iwase, A; Kikkawa, F; Kajiyama, H

JMA JOURNAL   Vol. 5 ( 2 ) page： 216 - 223   2022.4

Assessment of placental abruption with diffusion-weighted imaging Reviewed

Mizutani, T; Kotani, T; Kato, N; Imai, K; Ushida, T; Nakano-Kobayashi, T; Kinoshita, Y; Ito, M; Kinoshita, F; Yamamuro, O; Kajiyama, H

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH   Vol. 48 ( 4 ) page： 930 - 937   2022.4

Crosstalk between foetal vasoactive peptide hormones and placental aminopeptidases regulates placental blood flow: Its significance in preeclampsia Reviewed

Yoshihara, M; Mizutani, S; Matsumoto, K; Kato, Y; Masuo, Y; Tano, S; Mizutani, H; Kotani, T; Mizutani, E; Shibata, K; Kajiyama, H

PLACENTA   Vol. 121   page： 32 - 39   2022.4

Annual Body Mass Index Gain and Risk of Gestational Diabetes Mellitus in a Subsequent Pregnancy

Tano, S; Kotani, T; Ushida, T; Yoshihara, M; Imai, K; Nakano-Kobayashi, T; Moriyama, Y; Iitani, Y; Kinoshita, F; Yoshida, S; Yamashita, M; Kishigami, Y; Oguchi, H; Kajiyama, H

FRONTIERS IN ENDOCRINOLOGY   Vol. 13   page： 815390   2022.3

Effects of evidence-based ICU care on long-term outcomes of patients with sepsis or septic shock (ILOSS): protocol for a multicentre prospective observational cohort study in Japan

Liu, KB; Kotani, T; Nakamura, K; Chihiro, T; Morita, Y; Ishii, K; Fujizuka, K; Yasumura, D; Taniguchi, D; Hamagami, T; Shimojo, N; Nitta, M; Hongo, T; Akieda, K; Atsuo, M; Kaneko, T; Sakuda, Y; Andoh, K; Nagatomi, A; Tanaka, Y; Irie, Y; Kamijo, H; Hanazawa, M; Kasugai, D; Ayaka, M; Oike, K; Lefor, AK; Takahashi, K; Katsukawa, H; Ogura, T

BMJ OPEN   Vol. 12 ( 3 ) page： e054478   2022.3

Pre-pregnancy sleep duration and postpartum depression: a multicenter study in Japan Reviewed

Matsuo, S; Ushida, T; Iitani, Y; Imai, K; Nakano-Kobayashi, T; Moriyama, Y; Yoshida, S; Yamashita, M; Kajiyama, H; Kotani, T

ARCHIVES OF WOMENS MENTAL HEALTH   Vol. 25 ( 1 ) page： 181 - 189   2022.2

Clinical guide for women with mental health problems during the perinatal period Reviewed

Shimoya, K; Kotani, T; Satoh, S; Suzuki, S; Kashima, H; Ogasawara, K; Ozaki, N; Suzuki, E; Tachibana, Y; Suzuki, T

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH   Vol. 48 ( 1 ) page： 20 - 33   2022.1

Liver transaminase levels during pregnancy: a Japanese multicenter study

Ushida, T; Kotani, T; Kinoshita, F; Imai, K; Nakano-Kobayashi, T; Nakamura, N; Moriyama, Y; Yoshida, S; Yamashita, M; Kajiyama, H

JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE   Vol. 35 ( 25 ) page： 5761 - 5767   2022

Hypertensive disorders of pregnancy and alterations in brain metabolites in preterm infants: A multi-voxel proton MR spectroscopy study Reviewed

Katsuki, S; Ushida, T; Kidokoro, H; Nakamura, N; Iitani, Y; Fuma, K; Imai, K; Nakano-Kobayashi, T; Sato, Y; Hayakawa, M; Natsume, J; Kajiyama, H; Kotani, T

EARLY HUMAN DEVELOPMENT   Vol. 163   page： 105479   2021.12

Stepwise Treatment for Abnormally Invasive Placenta with Placenta Previa Reviewed

Sumigama, S; Kotani, T; Hayakawa, H

SURGERY JOURNAL   Vol. 07 ( Suppl 1 ) page： S20 - S27   2021.12

Prevalence and risk factors of labor-onset hypertension: A multicenter study in Japan Reviewed

Ushida, T; Kotani, T; Imai, K; Nakano-Kobayashi, T; Iitani, Y; Nakamura, N; Moriyama, Y; Yoshida, S; Yamashita, M; Kajiyama, H

PREGNANCY HYPERTENSION-AN INTERNATIONAL JOURNAL OF WOMENS CARDIOVASCULAR HEALTH   Vol. 26   page： 48 - 53   2021.12

高次医療機関における母体血を用いた出生前遺伝学的検査導入前後での羊水染色体検査状況の検討 Reviewed

橋本 佑樹, 村松 友佳子, 伊藤 美春, 齊藤 明子, 佐藤 義朗, 牛田 貴文, 小谷 友美, 早川 昌弘

日本周産期・新生児医学会誌     2021.12

Annual body mass index gain and risk of hypertensive disorders of pregnancy in a subsequent pregnancy Reviewed

Tano, S; Kotani, T; Ushida, T; Yoshihara, M; Imai, K; Nakano-Kobayashi, T; Moriyama, Y; Iitani, Y; Kinoshita, F; Yoshida, S; Yamashita, M; Kishigami, Y; Oguchi, H; Kajiyama, H

SCIENTIFIC REPORTS   Vol. 11 ( 1 ) page： 22519   2021.11

Tadalafil treatment for preeclampsia (medication in preeclampsia; MIE): a multicenter phase II clinical trial

Furuhashi, F; Tanaka, H; Maki, S; Tsuji, M; Magawa, S; Kaneda, MK; Nii, M; Tanaka, K; Ogura, T; Nishimura, Y; Endoh, M; Kimura, T; Kotani, T; Sekizawa, A; Ikeda, T

JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE   Vol. 34 ( 22 ) page： 3709 - 3715   2021.11

Upregulation of ENDOU in cytotrophoblasts from placenta complicated with preeclampsia and fetal growth restriction Reviewed

Nomoto, M; Kotani, T; Miki, R; Ushida, T; Imai, K; Iitani, Y; Tano, S; Wang, JW; Moriyama, Y; Kobayashi, T; Mimura, N; Iriyama, T; Kikkawa, F; Kajiyama, H

JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION   Vol. 69 ( 3 ) page： 280 - 285   2021.11

Manual removal of the placenta and postpartum hemorrhage: A multicenter retrospective study Reviewed

Fujita, K; Ushida, T; Imai, K; Nakano-Kobayashi, T; Iitani, Y; Matsuo, S; Yoshida, S; Yamashita, M; Kajiyama, H; Kotani, T

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH   Vol. 47 ( 11 ) page： 3867 - 3874   2021.11

Prenatal Molecular Hydrogen Administration Ameliorates Several Findings in Nitrofen-Induced Congenital Diaphragmatic Hernia Reviewed

Miura, M; Imai, K; Tsuda, H; Miki, R; Tano, S; Ito, Y; Hirako-Takamura, S; Moriyama, Y; Ushida, T; Iitani, Y; Nakano-Kobayashi, T; Toyokuni, S; Kajiyama, H; Kotani, T

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES   Vol. 22 ( 17 )   2021.9

Current Issues within the Perinatal Mental Health Care System in Aichi Prefecture, Japan: A Cross-Sectional Questionnaire Survey Reviewed

Fujita, K; Kotani, T; Moriyama, Y; Ushida, T; Imai, K; Kobayashi-Nakano, T; Kato, N; Kano, T; Kikkawa, F; Kajiyama, H

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH   Vol. 18 ( 17 )   2021.9

Impact of maternal hypertensive disorders of pregnancy on brain volumes at term-equivalent age in preterm infants: A voxel-based morphometry study Reviewed

Ushida, T; Kidokoro, H; Nakamura, N; Katsuki, S; Imai, K; Nakano-Kobayashi, T; Moriyama, Y; Sato, Y; Hayakawa, M; Natsume, J; Kajiyama, H; Kotani, T

PREGNANCY HYPERTENSION-AN INTERNATIONAL JOURNAL OF WOMENS CARDIOVASCULAR HEALTH   Vol. 25   page： 143 - 149   2021.8

Randomized Trial of Fetal Surgery for Severe Left Diaphragmatic Hernia. Reviewed International coauthorship

Deprest JA, Nicolaides KH, Benachi A, Gratacos E, Ryan G, Persico N, Sago H, Johnson A, Wielgoś M, Berg C, Van Calster B, Russo FM; TOTAL Trial for Severe Hypoplasia Investigators.

N Engl J Med   Vol. 385 ( 2 ) page： 107 - 118   2021.7

Antenatal prediction models for short- and medium-term outcomes in preterm infants

Ushida, T; Moriyama, Y; Nakatochi, M; Kobayashi, Y; Imai, K; Nakano-Kobayashi, T; Nakamura, N; Hayakawa, M; Kajiyama, H; Kotani, T

ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA   Vol. 100 ( 6 ) page： 1089 - 1096   2021.6

Platelet counts during normal pregnancies and pregnancies complicated with hypertensive disorders Reviewed

Ushida, T; Kotani, T; Moriyama, Y; Imai, K; Nakano-Kobayashi, T; Kinoshita, F; Nakamura, N; Iitani, Y; Yoshida, S; Yamashita, M; Kajiyama, H

PREGNANCY HYPERTENSION-AN INTERNATIONAL JOURNAL OF WOMENS CARDIOVASCULAR HEALTH   Vol. 24   page： 73 - 78   2021.6

Assessment of myocardial performance index in late-onset fetal growth restriction Reviewed International coauthorship

Nguyen, TTN; Kotani, T; Imai, K; Ushida, T; Moriyama, Y; Kobayashi, T; Niimi, K; Sumigama, S; Yamamoto, E; Vo, VD; Le, MT; Le, LH; Nguyen, DN; Nguyen, VQH; Truong, QV; Cao, NT; Kikkawa, F

NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 83 ( 2 ) page： 259 - 268   2021.5

Postpartum alterations following inflammation in rat pregnancy: a discovery proteomic analysis Reviewed International coauthorship

Ushida, T; Kotani, T; Moriyama, Y; Hindmarch, CCT; Cotechini, T; Imai, K; Nakano-Kobayashi, T; Kajiyama, H; Graham, CH

REPRODUCTION   Vol. 161 ( 5 ) page： 513 - 522   2021.5

Vitamin D improves pulmonary function in a rat model for congenital diaphragmatic hernia

Ito, Y; Tsuda, H; Imai, K; Miki, R; Miura, M; Tachi, A; Tano, S; Hirako-Takamura, S; Moriyama, Y; Ushida, T; Kobayashi, T; Sumigama, S; Kajiyama, H; Kikkawa, F; Kotani, T

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS   Vol. 700   page： 108769   2021.3

Trisomy 5p with bilateral congenital diaphragmatic hernia: a case report

Nakamura, N; Ushida, T; Moriyama, Y; Imai, K; Nakano-Kobayashi, T; Osuka, S; Goto, M; Kajiyama, H; Asada, H; Hayakawa, M; Kotani, T

JOURNAL OF MEDICAL CASE REPORTS   Vol. 15 ( 1 ) page： 114   2021.3

Maternal low birth weight and hypertensive disorders of pregnancy

Ushida, T; Kotani, T; Kinoshita, F; Imai, K; Nakano-Kobayashi, T; Nakamura, N; Moriyama, Y; Yoshida, S; Yamashita, M; Kajiyama, H

PREGNANCY HYPERTENSION-AN INTERNATIONAL JOURNAL OF WOMENS CARDIOVASCULAR HEALTH   Vol. 23   page： 5 - 10   2021.3

Shock Index and Postpartum Hemorrhage in Vaginal Deliveries: A Multicenter Retrospective Study

Ushida, T; Kotani, T; Imai, K; Nakano-Kobayashi, T; Nakamura, N; Moriyama, Y; Yoshida, S; Yamashita, M; Kajiyama, H; Kikkawa, F

SHOCK   Vol. 55 ( 3 ) page： 332 - 337   2021.3

Multiple cytokine analysis in gastroschisis: Association with adverse outcomes including fetal brain damage

Owaki, T; Imai, K; Miki, R; Niwa, Y; Kotani, T; Nakano-Kobayashi, T; Ushida, T; Kajiyama, H

CYTOKINE   Vol. 138   page： 155406   2021.2

Mortality and neurological outcomes in extremely and very preterm infants born to mothers with hypertensive disorders of pregnancy

Nakamura, N; Ushida, T; Nakatochi, M; Kobayashi, Y; Moriyama, Y; Imai, K; Nakano-Kobayashi, T; Hayakawa, M; Kajiyama, H; Kikkawa, F; Kotani, T

SCIENTIFIC REPORTS   Vol. 11 ( 1 ) page： 1729   2021.1

Very Low Levels of Serum Anti-Mullerian Hormone as a Possible Marker for Follicle Growth in Patients with Primary Ovarian Insufficiency Under Hormone Replacement Therapy

Kasahara, Y; Osuka, S; Bayasula; Nakanishi, N; Murase, T; Nakamura, T; Goto, M; Kotani, T; Iwase, A; Kikkawa, F

REPRODUCTIVE SCIENCES   Vol. 28 ( 1 ) page： 31 - 36   2021.1

Feasibility and outcomes of fetoscopic endoluminal tracheal occlusion for severe congenital diaphragmatic hernia: A Japanese experience

Wada, S; Ozawa, K; Sugibayashi, R; Suyama, F; Amari, S; Ito, Y; Kanamori, Y; Okuyama, H; Usui, N; Sasahara, J; Kotani, T; Hayakawa, M; Kato, K; Taguchi, T; Endo, M; Sago, H

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH   Vol. 46 ( 12 ) page： 2598 - 2604   2020.12

Focal Adhesion Kinase-Mediated Sequences, Including Cell Adhesion, Inflammatory Response, and Fibrosis, as a Therapeutic Target in Endometriosis

Nagai, T; Ishida, C; Nakamura, T; Iwase, A; Mori, M; Murase, T; Bayasula; Osuka, S; Takikawa, S; Goto, M; Kotani, T; Kikkawa, F

REPRODUCTIVE SCIENCES   Vol. 27 ( 7 ) page： 1400 - 1410   2020.7

Antenatal corticosteroids and preterm offspring outcomes in hypertensive disorders of pregnancy: A Japanese cohort study

Ushida, T; Kotani, T; Hayakawa, M; Hirakawa, A; Sadachi, R; Nakamura, N; Moriyama, Y; Imai, K; Nakano-Kobayashi, T; Kikkawa, F

SCIENTIFIC REPORTS   Vol. 10 ( 1 ) page： 9312   2020.6

Antenatal Corticosteroids and Outcomes in Preterm Twins

Ushida, T; Kotani, T; Sadachi, R; Hirakawa, A; Hayakawa, M; Moriyama, Y; Imai, K; Nakano-Kobayashi, T; Kikkawa, F

OBSTETRICS AND GYNECOLOGY   Vol. 135 ( 6 ) page： 1387 - 1397   2020.6

A proteome signature of umbilical cord serum associated with congenital diaphragmatic hernia

Tachi, A; Moriyama, Y; Tsuda, H; Miki, R; Ushidai, T; Miura, M; Ito, Y; Imail, K; Nakano-Kobayashi, I; Hayakawa, M; Kikkawa, F; Kotani, T

NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 82 ( 2 ) page： 345 - 354   2020.5

The management of hydatidiform mole using prophylactic chemotherapy and hysterectomy for high-risk patients decreased the incidence of gestational trophoblastic neoplasia in Vietnam: a retrospective observational study.

Yamamoto E, Trinh TD, Sekiya Y, Tamakoshi K, Nguyen XP, Nishino K, Niimi K, Kotani T, Kajiyama H, Shibata K, Le QT, Kikkawa F

Nagoya journal of medical science   Vol. 82 ( 2 ) page： 183 - 191   2020.5

Determination of the cytokine levels in fetal pleural effusion and their association with fetal/neonatal findings

Imai, K; Kotani, T; Tsuda, H; Kobayashi, T; Ushida, T; Moriyama, Y; Kikkawa, F

CYTOKINE   Vol. 127   page： 154945   2020.3

Two-photon microscopic observation of cell-production dynamics in the developing mammalian neocortex in utero

Kawasoe, R; Shinoda, T; Hattori, Y; Nakagawa, M; Pham, TQ; Tanaka, Y; Sagou, K; Saito, K; Katsuki, S; Kotani, T; Sano, A; Fujimori, T; Miyata, T

DEVELOPMENT GROWTH & DIFFERENTIATION   Vol. 62 ( 2 ) page： 118 - 128   2020.2

Outcome of cesarean scar pregnancy treated with local methotrexate injection

Tam, LM; Kotani, T; Linh, TM; Thu, PTM; Khanh, TV; Anh, NTK; Nguyen, NTT; Moriyama, Y; Yamamoto, E; Huy, NVQ; Vinh, TQ; Thanh, CN; Kikkawa, F

NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 82 ( 1 ) page： 15 - 23   2020.2

The efficacy and toxicity of 4-day chemotherapy with methotrexate, etoposide and actinomycin D in patients with choriocarcinoma and high-risk gestational trophoblastic neoplasia

Sato, S; Yamamoto, E; Niimi, K; Ino, K; Nishino, K; Suzuki, S; Kotani, T; Kajiyama, H; Kikkawa, F

INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY   Vol. 25 ( 1 ) page： 203 - 209   2020.1

Adverse effects of endometriosis on pregnancy: a case-control study

Miura, M; Ushida, T; Imai, K; Wang, JW; Moriyama, Y; Nakano-Kobayashi, T; Osuka, S; Kikkawa, F; Kotani, T

BMC PREGNANCY AND CHILDBIRTH   Vol. 19 ( 1 ) page： 373   2019.10

A pitfall in diagnosing fetal abdominal lymphangioma: A report of two cases.

Niwa Y, Imai K, Kotani T, Nakano T, Ushida T, Moriyama Y, Kikkawa F

Journal of clinical ultrasound : JCU   Vol. 47 ( 8 ) page： 494 - 496   2019.10

Findings of amplitude-integrated electroencephalogram recordings and serum vitamin B6 metabolites in perinatal lethal hypophosphatasia during enzyme replacement therapy.

Ishiguro T, Sugiyama Y, Ueda K, Muramatsu Y, Tsuda H, Kotani T, Michigami T, Tachikawa K, Akiyama T, Hayakawa M

Brain & development   Vol. 41 ( 8 ) page： 721 - 725   2019.9

Maternal protein S activity is associated with massive hemorrhage during caesarean section: retrospective case-control study.

Imai K, Kotani T, Nakano T, Ushida T, Hirakawa A, Kikkawa F

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians   Vol. 32 ( 16 ) page： 2633 - 2637   2019.8

Feasibility of using a handheld tissue hardness meter to quantify uterine contractions and its clinical application for obstetric bleeding management

Imai Kenji, Kotani Tomomi, Ushida Takafumi, Moriyama Yoshinori, Nakano Tomoko, Kikkawa Fumitaka

JOURNAL OF OBSTETRICS AND GYNAECOLOGY   Vol. 39 ( 6 ) page： 757 - 762   2019.8

Increased LIGHT leading to sFlt-1 elevation underlies the pathogenic link between hydatidiform mole and preeclampsia.

Iriyama T, Wang G, Yoshikawa M, Mimura N, Matsui H, Sayama S, Kumasawa K, Nagamatsu T, Koga K, Kotani T, Niimi K, Yamamoto E, Kellems RE, Xia Y, Osuga Y, Fujii T

Scientific reports   Vol. 9 ( 1 ) page： 10107   2019.7

Serological screening of immunoglobulin M and immunoglobulin G during pregnancy for predicting congenital cytomegalovirus infection

Torii, Y; Yoshida, S; Yanase, Y; Mitsui, T; Horiba, K; Okumura, T; Takeuchi, S; Suzuki, T; Kawada, J; Kotani, T; Yamashita, M; Ito, Y

BMC PREGNANCY AND CHILDBIRTH   Vol. 19 ( 1 ) page： 205   2019.6

Safety Evaluation of Tadalafil Treatment for Fetuses with Early-Onset Growth Restriction (TADAFER): Results from the Phase II Trial

Maki, S; Tanaka, H; Tsuji, M; Furuhashi, F; Magawa, S; Kaneda, MK; Nii, M; Tanaka, K; Kondo, E; Tamaru, S; Ogura, T; Nishimura, Y; Endoh, M; Kimura, T; Kotani, T; Sekizawa, A; Ikeda, T

JOURNAL OF CLINICAL MEDICINE   Vol. 8 ( 6 )   2019.6

Somatic symptom disorder manifested as acute abdominal pain during pregnancy preceding perinatal depression: a case report.

Moriyama Y, Imai K, Nakano T, Kotani T, Kikkawa F

Archives of women's mental health   Vol. 22 ( 2 ) page： 301 - 304   2019.4

Relationship between cytokine profiles of cord blood and cord S100B levels in preterm infants

Niwa, Y; Imai, K; Kotani, T; Miki, R; Nakano, T; Ushida, T; Moriyama, Y; Kikkawa, F

EARLY HUMAN DEVELOPMENT   Vol. 129   page： 65 - 70   2019.2

Isolation of group B <i>Streptococcus</i> with reduced β-lactam susceptibility from pregnant women

Moroi, H; Kimura, K; Kotani, T; Tsuda, H; Banno, H; Jin, W; Wachino, J; Yamada, K; Mitsui, T; Yamashita, M; Kikkawa, F; Arakawa, Y

EMERGING MICROBES & INFECTIONS   Vol. 8 ( 1 ) page： 2 - 7   2019.1

The role of E2F8 in the human placenta

Mizuno Masako, Miki Rika, Moriyama Yoshinori, Ushida Takafumi, Imai Kenji, Niimi Kaoru, Nakano Tomoko, Tsuda Hiroyuki, Sumigama Seiji, Yamamoto Eiko, Senga Takeshi, Iwase Akira, Kikkawa Fumitaka, Kotani Tomomi

MOLECULAR MEDICINE REPORTS   Vol. 19 ( 1 ) page： 293 - 301   2019.1

Possible Association between Cathepsin V and the Development of Placenta Accreta Spectrum Disorders

Matsukawa, S; Sumigama, S; Kotani, T; Wang, JW; Miki, R; Moriyama, Y; Nakano, T; Mano, Y; Tsuda, H; Tamakoshi, K; Kikkawa, F

GYNECOLOGIC AND OBSTETRIC INVESTIGATION   Vol. 84 ( 4 ) page： 396 - 406   2019

Clinical utility and limitations of FibCare (R) for the rapid measurement of fibrinogen concentrations: The first clinical experience

Imai Kenji, Kotani Tomomi, Nakano Tomoko, Ushida Takafumi, Kikkawa Fumitaka

TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY   Vol. 57 ( 6 ) page： 899 - 900   2018.12

A rare pseudo tumour in the extraembryonic coelom in first trimester of pregnancy: ultrasound and pathology.

Sumigama S, Enomoto A, Matsukawa S, Ushida T, Imai K, Nakano T, Kotani T, Kikkawa F

Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology     page： 1-2   2018.11

Protective effects of mangafodipir against chemotherapy-induced ovarian damage in mice

Qin, Y; Iwase, A; Murase, T; Bayasula; Ishida, C; Kato, N; Nakamura, T; Osuka, S; Takikawa, S; Goto, M; Kotani, T; Kikkawa, F

REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY   Vol. 16 ( 1 ) page： 106   2018.10

TADAFER II: Tadalafil treatment for fetal growth restriction - a study protocol for a multicenter randomised controlled phase II trial

Umekawa Takashi, Maki Shintaro, Kubo Michiko, Tanaka Hiroaki, Nii Masafumi, Tanaka Kayo, Osato Kazuhiro, Kamimoto Yuki, Tamaru Satoshi, Ogura Toru, Nishimura Yuki, Kodera Mayumi, Minamide Chisato, Nishikawa Masakatsu, Endoh Masayuki, Kimura Tadashi, Kotani Tomomi, Nakamura Masamitsu, Sekizawa Akihiko, Ikeda Tomoaki

BMJ OPEN   Vol. 8 ( 10 ) page： e020948   2018.10

The impact of fertility treatment on the neonatal respiratory outcomes and amniotic lamellar body counts in twin pregnancies

Tsuda Hiroyuki, Kotani Tomomi, Nakano Tomoko, Imai Kenji, Ushida Takafumi, Hirakawa Akihiro, Kinoshita Fumie, Takahashi Yuichiro, Iwagaki Shigenori, Kikkawa Fumitaka

CLINICA CHIMICA ACTA   Vol. 484   page： 192 - 196   2018.9

The rate of neonatal respiratory distress syndrome/transient tachypnea in the newborn and the amniotic lamellar body count in twin pregnancies compared with singleton pregnancies

Tsuda Hiroyuki, Kotani Tomomi, Nakano Tomoko, Imai Kenji, Ushida Takafumi, Hirakawa Akihiro, Kinoshita Fumie, Takahashi Yuichiro, Iwagaki Shigenori, Kikkawa Fumitaka

CLINICA CHIMICA ACTA   Vol. 484   page： 293 - 297   2018.9

Thyroid Autoantibodies do not Impair the Ovarian Reserve in Euthyroid Infertile Women: A Cross-Sectional Study

Osuka Satoko, Iwase Akira, Goto Maki, Takikawa Sachiko, Nakamura Tomoko, Murase Tomohiko, Kato Nao, Bayasula, Kotani Tomomi, Kikkawa Fumitaka

HORMONE AND METABOLIC RESEARCH   Vol. 50 ( 7 ) page： 537 - 542   2018.7

Administration of molecular hydrogen during pregnancy improves behavioral abnormalities of offspring in a maternal immune activation model

Imai Kenji, Kotani Tomomi, Tsuda Hiroyuki, Nakano Tomoko, Ushida Takafumi, Iwase Akira, Nagai Taku, Toyokuni Shinya, Suzumura Akio, Kikkawa Fumitaka

SCIENTIFIC REPORTS   Vol. 8 ( 1 ) page： 9221   2018.6

Effect of molecular hydrogen on uterine inflammation during preterm labour

Nakano Tomoko, Kotani Tomomi, Imai Kenji, Iitani Yukako, Ushida Takafumi, Tsuda Hiroyuki, Li Hua, Iwase Akira, Toyokuni Shinya, Kikkawa Fumitaka

BIOMEDICAL REPORTS   Vol. 8 ( 5 ) page： 454 - 460   2018.5

Dengue fever during pregnancy.

Tien Dat T, Kotani T, Yamamoto E, Shibata K, Moriyama Y, Tsuda H, Yamashita M, Kajiyama H, Duc Thien Minh D, Quang Thanh L, Kikkawa F

Nagoya journal of medical science   Vol. 80 ( 2 ) page： 241 - 247   2018.5

Altered proteomic profile in umbilical arterial serum from mothers with schizophrenia.

Moriyama Y, Kotani T, Ushida T, Imai K, Nakano T, Tsuda H, Kikkawa F

Schizophrenia research     2018.3

Follicle dynamics: visualization and analysis of follicle growth and maturation using murine ovarian tissue culture.

Murase T, Iwase A, Komatsu K, Bayasula, Nakamura T, Osuka S, Takikawa S, Goto M, Kotani T, Kikkawa F

Journal of assisted reproduction and genetics   Vol. 35 ( 2 ) page： 339-343   2018.2

The expression of Toll-like receptor 5 in preterm histologic chorioamnionitis.

Moroi H, Kotani T, Miki R, Tsuda H, Mizuno M, Ito Y, Ushida T, Imai K, Nakano T, Li H, Sumigama S, Yamamoto E, Iwase A, Kikkawa F

Journal of clinical biochemistry and nutrition   Vol. 62 ( 1 ) page： 63 - 67   2018.1

Simulation training is useful for shortening the decision-to-delivery interval in cases of emergent cesarean section.

Iitani Y, Tsuda H, Ito Y, Moriyama Y, Nakano T, Imai K, Kotani T, Kikkawa F

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians   Vol. 31 ( 23 ) page： 3128 - 3132   2018

Association of serum asymmetric dimethylarginine, homocysteine, and L-arginine concentrations during early pregnancy with hypertensive disorders of pregnancy

Maruta Ei, Wang Jingwen, Kotani Tomomi, Tsuda Hiroyuki, Nakano Tomoko, Imai Kenji, Sumigama Seiji, Niwa Yoshimitsu, Mitsui Takashi, Yoshida Shigeru, Yamashita Mamoru, Nawa Akihiro, Tamakoshi Koji, Kajiyama Hiroaki, Kikkawa Fumitaka

CLINICA CHIMICA ACTA   Vol. 475   page： 70 - 77   2017.12

Role of catalytic iron and oxidative stress in nitrofen-induced congenital diaphragmatic hernia and its amelioration by Saireito (TJ-114)

Hirako Shima, Tsuda Hiroyuki, Ito Fumiya, Okazaki Yasumasa, Hirayama Tasuku, Nagasawa Hideko, Nakano Tomoko, Imai Kenji, Kotani Tomomi, Kikkawa Fumitaka, Toyokuni Shinya

JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION   Vol. 61 ( 3 ) page： 176 - 182   2017.11

ABERRANT MATERNAL INFLAMMATION IN PREGNANCY LEADS TO PERSISTENCE OF RISK FACTORS FOR CARDIOVASCULAR DISEASE IN THE OFFSPRING

Ushida Takafumi, Macdonald-Goodfellow Shannyn, Tse M. Yat, Winn Louise, Pang Stephen, Adams Michael, Kotani Tomomi, Kikkawa Fumitaka, Graham Charles

PLACENTA   Vol. 57   page： 243 - 243   2017.9

Establishment and characterization of cell lines derived from complete hydatidiform mole

Yamamoto Eiko, Niimi Kaoru, Kiyono Tohru, Yamamoto Toshimichi, Nishino Kimihiro, Nakamura Kenichi, Kotani Tomomi, Kajiyama Hiroaki, Shibata Kiyosumi, Kikkawa Fumitaka

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE   Vol. 40 ( 3 ) page： 614 - 622   2017.9

PERSISTENCE OF RISK FACTORS ASSOCIATED WITH MATERNAL CARDIOVASCULAR DISEASE FOLLOWING ABERRANT INFLAMMATION IN RAT PREGNANCY

Ushida, T; Macdonald-Goodfellow, S; Quadri, A; Tse, MY; Winn, L; Pang, S; Adams, M; Kotani, T; Kikkawa, F; Graham, C

PLACENTA   Vol. 57   page： 279 - 279   2017.9

Persistence of risk factors associated with maternal cardiovascular disease following aberrant inflammation in rat pregnancy

Ushida Takafumi, Macdonald-Goodfellow Shannyn K., Quadri Allegra, Tse M. Yat, Winn Louise M., Pang Stephen C., Adams Michael A., Kotani Tomomi, Kikkawa Fumitaka, Graham Charles H.

BIOLOGY OF REPRODUCTION   Vol. 97 ( 1 ) page： 143 - 152   2017.7

c-Rel Promotes Invasion of Choriocarcinoma Cells via PI3K/AKT Signaling. Reviewed

Sekiya Y, Yamamoto E, Niimi K, Nishino K, Nakamura K, Kotani T, Kajiyama H, Shibata K, Kikkawa F

Oncology   Vol. 92 ( 5 )   2017.3

A Novel Approach to Detecting Postpartum Hemorrhage Using Contrast-Enhanced Ultrasound. Reviewed

Imai K, Kotani T, Tsuda H, Nakano T, Hirakawa A, Kikkawa F

Ultrasound in medicine & biology   Vol. 43 ( 3 ) page： 615-620   2017.3

Observed-to-expected MRI fetal lung volume can predict long-term lung morbidity in infants with congenital diaphragmatic hernia. Reviewed

Tsuda H, Kotani T, Miura M, Ito Y, Hirako S, Nakano T, Imai K, Kikkawa F

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians   Vol. 30 ( 13 ) page： 1509 - 1513   2017

A large mediastinal tumour invading into the liver with foetal hydrops: A rare case of infantile myofibromatosis

Ushida Takafumi, Tsuda Hiroyuki, Takahara Taishi, Takahashi Yuichiro, Kotani Tomomi, Kikkawa Fumitaka

JOURNAL OF OBSTETRICS AND GYNAECOLOGY   Vol. 37 ( 6 ) page： 821 - 823   2017

Kisspeptin in the hypothalamus of two rat models of polycystic ovary syndrome. Reviewed

Osuka S, Iwase A, Nakahara T, Kondo M, Saito A, Bayasula, Nakamura T, Takikawa S, Goto M, Kotani T, Kikkawa F

Endocrinology     page： en20161333   2016.12

Oncologic and obstetric outcomes of early stage cervical cancer with abdominal radical trachelectomy: Single-institution experience. Reviewed

Tamauchi S, Kajiyama H, Sakata J, Sekiya R, Suzuki S, Mizuno M, Utsumi F, Niimi K, Kotani T, Shibata K, Kikkawa F

The journal of obstetrics and gynaecology research   Vol. 42 ( 12 ) page： 1796-1801   2016.12

Molecular hydrogen ameliorates several characteristics of preeclampsia in the Reduced Uterine Perfusion Pressure (RUPP) rat model. Reviewed

Ushida T, Kotani T, Tsuda H, Imai K, Nakano T, Hirako S, Ito Y, Li H, Mano Y, Wang J, Miki R, Yamamoto E, Iwase A, Bando YK, Hirayama M, Ohno K, Toyokuni S, Kikkawa F

Free radical biology & medicine   Vol. 101   page： 524-533   2016.12

Molecular hydrogen ameliorates several characteristics of preeclampsia in the Reduced Uterine Perfusion Pressure (RUPP) rat model Reviewed

Ushida T, Kotani T, Tsuda H, Imai K, Nakano T, Hirako S, Ito Y, Li H, Mano Y3, Wang J4, Miki R4, Yamamoto E5, Iwase A1, Bando YK6, Hirayama M7, Ohno K7, Toyokuni S8, Kikkawa F1.

Free Radic Biol Med   Vol. 101   page： 524-533   2016.12

Lipocalin 2 as a new biomarker for fetal lung hypoplasia in congenital diaphragmatic hernia. Reviewed

Tsuda H, Kotani T, Nakano T, Imai K, Hirako S, Li H, Kikkawa F

Clinica chimica acta; international journal of clinical chemistry   Vol. 462   page： 71-76   2016.11

Serum pentraxin 3 as a possible marker for mature cystic teratomas. Reviewed

Ishida C, Iwase A, Osuka S, Goto M, Takikawa S, Nakamura T, Kotani T, Kikkawa F

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology   Vol. 32 ( 9 ) page： 733-736   2016.9

Antenatal Saireito (TJ-114) Can Improve Pulmonary Hypoplasia and Pulmonary Vascular Remodeling in Nitrofen-Induced Congenital Diaphragmatic Hernia. Reviewed

Hirako S, Tsuda H, Kotani T, Sumigama S, Mano Y, Nakano T, Imai K, Li H, Toyokuni S, Kikkawa F

Phytotherapy research : PTR   Vol. 30 ( 9 ) page： 1474-80   2016.9

Increase of kisspeptin-positive cells in the hypothalamus of a rat model of polycystic ovary syndrome. Reviewed

Kondo M, Osuka S, Iwase A, Nakahara T, Saito A, Bayasula, Nakamura T, Goto M, Kotani T, Kikkawa F

Metabolic brain disease   Vol. 31 ( 3 ) page： 673-81   2016.6

Severe Hemoperitoneum During Pregnancy with Obstructed Hemivagina and Ipsilateral Renal Anomaly Syndrome: A Case Report. Reviewed

Muraoka A, Tsuda H, Kotani T, Kikkawa F

The Journal of reproductive medicine   Vol. 61 ( 5-6 ) page： 290-4   2016.5

Pain-reducing anesthesia prevents oxidative stress in human term placenta. Reviewed

Tsuzuki Y, Yamashita Y, Hattori Y, Hua Li G, Akatsuka S, Kotani T, Kikkawa F, Naiki-Ito A, Takahashi S, Nishiwaki K, Toyokuni S

Journal of clinical biochemistry and nutrition   Vol. 58 ( 2 ) page： 156-60   2016.3

Efficacy and safety of daikenchuto (TJ-100) in pregnant women with constipation. Reviewed

Tsuda H, Kotani T, Sumigama S, Mano Y, Hayakawa H, Kikkawa F

Taiwanese journal of obstetrics & gynecology   Vol. 55 ( 1 ) page： 26-9   2016.2

Neuroprotective potential of molecular hydrogen against perinatal brain injury via suppression of activated microglia. Reviewed

Imai K, Kotani T, Tsuda H, Mano Y, Nakano T, Ushida T, Li H, Miki R, Sumigama S, Iwase A, Hirakawa A, Ohno K, Toyokuni S, Takeuchi H, Mizuno T, Suzumura A, Kikkawa F

Free radical biology & medicine   Vol. 91   page： 154-63   2016.2

Relationship between the cortisol levels in umbilical cord blood and neonatal RDS/TTN in twin pregnancies. Reviewed

Tsuda H, Kotani T, Sumigama S, Mano Y, Nakano T, Hua L, Kikkawa F

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians   Vol. 29 ( 13 ) page： 2151-6   2016

Risk assessment for neonatal RDS/TTN using gestational age and the amniotic lamellar body count in twin pregnancies. Reviewed

Tsuda H, Hirakawa A, Kotani T, Sumigama S, Mano Y, Nakano T, Imai K, Kawabata I, Takahashi Y, Iwagaki S, Kikkawa F

Clinica chimica acta; international journal of clinical chemistry   Vol. 451 ( Pt B ) page： 301-4   2015.12

Maternal molecular hydrogen administration on lipopolysaccharide-induced mouse fetal brain injury. Reviewed

Nakano T, Kotani T, Mano Y, Tsuda H, Imai K, Ushida T, Li H, Miki R, Sumigama S, Sato Y, Iwase A, Hirakawa A, Asai M, Toyokuni S, Kikkawa F

Journal of clinical biochemistry and nutrition   Vol. 57 ( 3 ) page： 178-82   2015.11

Is the serum l-arginine level during early pregnancy a predictor of pregnancy-induced hypertension? Reviewed

Wang J, Kotani T, Tsuda H, Mano Y, Sumigama S, Li H, Komatsu K, Miki R, Maruta E, Niwa Y, Mitsui T, Yoshida S, Yamashita M, Tamakoshi K, Kikkawa F

Journal of clinical biochemistry and nutrition   Vol. 57 ( 1 ) page： 74-81   2015.7

Impact of warning bleeding on the cortisol level in the fetus and neonatal RDS/TTN in cases of placenta previa. Reviewed

Tsuda H, Kotani T, Sumigama S, Mano Y, Hua L, Kikkawa F

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians   Vol. 28 ( 9 ) page： 1057-60   2015.6

Viral load in children with congenital cytomegalovirus infection identified on newborn hearing screening. Reviewed

Kawada J, Torii Y, Kawano Y, Suzuki M, Kamiya Y, Kotani T, Kikkawa F, Kimura H, Ito Y

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology   Vol. 65   page： 41-5   2015.4

CYP51A1 induced by growth differentiation factor 9 and follicle-stimulating hormone in granulosa cells is a possible predictor for unfertilization. Reviewed

Nakamura T, Iwase A, Bayasula B, Nagatomo Y, Kondo M, Nakahara T, Takikawa S, Goto M, Kotani T, Kiyono T, Kikkawa F

Reproductive sciences (Thousand Oaks, Calif.)   Vol. 22 ( 3 ) page： 377-84   2015.3

Amniotic lamellar body count: predicting and distinguishing neonatal respiratory complications in twin pregnancies. Reviewed

Tsuda H, Kotani T, Sumigama S, Mano Y, Kawabata I, Takahashi Y, Iwagaki S, Hirakawa A, Kikkawa F

Clinica chimica acta; international journal of clinical chemistry   Vol. 441   page： 75-8   2015.2

Catalytic ferrous iron in amniotic fluid as a predictive marker of human maternal-fetal disorders. Reviewed

Hattori Y, Mukaide T, Jiang L, Kotani T, Tsuda H, Mano Y, Sumigama S, Hirayama T, Nagasawa H, Kikkawa F, Toyokuni S

Journal of clinical biochemistry and nutrition   Vol. 56 ( 1 ) page： 57-63   2015.1

Administration of umbilical cord blood cells transiently decreased hypoxic-ischemic brain injury in neonatal rats. Reviewed

Hattori T, Sato Y, Kondo T, Ichinohashi Y, Sugiyama Y, Yamamoto M, Kotani T, Hirata H, Hirakawa A, Suzuki S, Tsuji M, Ikeda T, Nakanishi K, Kojima S, Blomgren K, Hayakawa M

Developmental neuroscience   Vol. 37 ( 2 ) page： 95-104   2015

Guidelines for obstetrical practice in Japan: Japan Society of Obstetrics and Gynecology (JSOG) and Japan Association of Obstetricians and Gynecologists (JAOG) 2014 edition. Reviewed

Minakami H, Maeda T, Fujii T, Hamada H, Iitsuka Y, Itakura A, Itoh H, Iwashita M, Kanagawa T, Kanai M, Kasuga Y, Kawabata M, Kobayashi K, Kotani T, Kudo Y, Makino Y, Matsubara S, Matsuda H, Miura K, Murakoshi T, Murotsuki J, Ohkuchi A, Ohno Y, Ohshiba Y, Satoh S, Sekizawa A, Sugiura M, Suzuki S, Takahashi T, Tsukahara Y, Unno N, Yoshikawa H

The journal of obstetrics and gynaecology research   Vol. 40 ( 6 ) page： 1469-99   2014.6

Maternal molecular hydrogen administration ameliorates rat fetal hippocampal damage caused by in utero ischemia-reperfusion. Reviewed

Mano Y, Kotani T, Ito M, Nagai T, Ichinohashi Y, Yamada K, Ohno K, Kikkawa F, Toyokuni S

Free radical biology & medicine   Vol. 69   page： 324-30   2014.4

Effect of placenta previa on neonatal respiratory disorders and amniotic lamellar body counts at 36-38weeks of gestation. Reviewed

Tsuda H, Kotani T, Sumigama S, Mano Y, Hua L, Hayakawa H, Hayakawa M, Sato Y, Kikkawa F

Early human development   Vol. 90 ( 1 ) page： 51-4   2014.1

Possible involvement of CD10 in the development of endometriosis due to its inhibitory effects on CD44-dependent cell adhesion. Reviewed

Iwase A, Kotani T, Goto M, Kobayashi H, Takikawa S, Nakahara T, Nakamura T, Kondo M, Bayasula, Nagatomo Y, Kikkawa F

Reproductive sciences (Thousand Oaks, Calif.)   Vol. 21 ( 1 ) page： 82-8   2014.1

Altered expression of enzymes regulating the activity of endothelin-1 in the lower segment of the human amnion during labor.

Kotani T, Iwase A, Tsuda H, Mano Y, Yamamoto E, Nakano T, Hasegawa Y, Li H, Sumigama S, Itakura A, Kikkawa F

Biol Reprod   Vol. 89 ( 3 )   2013.9

A proteomic analysis of human follicular fluid: comparison between fertilized oocytes and non-fertilized oocytes in the same patient. Reviewed

Bayasula, Iwase A, Kobayashi H, Goto M, Nakahara T, Nakamura T, Kondo M, Nagatomo Y, Kotani T, Kikkawa F

Journal of assisted reproduction and genetics   Vol. 30 ( 9 ) page： 1231-8   2013.9

Altered expression of enzymes regulating the activity of endothelin-1 in the lower segment of the human amnion during labor. Reviewed

Kotani T, Iwase A, Tsuda H, Mano Y, Yamamoto E, Nakano T, Hasegawa Y, Li H, Sumigama S, Itakura A, Kikkawa F

Biology of reproduction   Vol. 89 ( 3 ) page： 52   2013.9

The expression and characterization of endoglin in uterine leiomyosarcoma. Reviewed

Mitsui H, Shibata K, Mano Y, Suzuki S, Umezu T, Mizuno M, Yamamoto E, Kajiyama H, Kotani T, Senga T, Kikkawa F

Clinical & experimental metastasis   Vol. 30 ( 6 ) page： 731-40   2013.8

Amniotic lamellar body count and congenital diaphragmatic hernia in humans and in a rat model. Reviewed

Watanabe Y, Tsuda H, Kotani T, Sumigama S, Mano Y, Hayakawa M, Sato Y, Kikkawa F

Pediatric research   Vol. 73 ( 3 ) page： 344-8   2013.3

Mucinous cystic neoplasm of the pancreas with severe dysplasia during pregnancy: case report and review of the literature. Reviewed

Tsuda H, Kotani T, Sumigama S, Mano Y, Shimoyama Y, Kikkawa F

Taiwanese journal of obstetrics & gynecology   Vol. 51 ( 4 ) page： 635-8   2012.12

A case report of placental mesenchymal dysplasia with an increased VEGF-D expression.

Kotani T, Sumigama S, Tsuda H, Mano Y, Yamamoto E, Iwase A, Shimoyama Y, Nagasaka T, Hayakawa H, Yamamoto T, Ino K, Kikkawa F.

Placenta   Vol. 33 ( 10 ) page： 888-91   2012.10

Sphingosine-1-phosphate inhibits H2O2-induced granulosa cell apoptosis via the PI3K/Akt signaling pathway. Reviewed

Nakahara T, Iwase A, Nakamura T, Kondo M, Bayasula, Kobayashi H, Takikawa S, Manabe S, Goto M, Kotani T, Kikkawa F

Fertility and sterility   Vol. 98 ( 4 ) page： 1001-8.e1   2012.10

Validity of lamellar body count as a fetal lung maturity assessment in twin pregnancy. Reviewed

Tsuda H, Kotani T, Sumigama S, Kawabata I, Takahashi Y, Iwagaki S, Kigoshi K, Kikkawa F

Twin research and human genetics : the official journal of the International Society for Twin Studies   Vol. 15 ( 4 ) page： 547-9   2012.8

Establishment of a human nonluteinized granulosa cell line that transitions from the gonadotropin-independent to the gonadotropin-dependent status. Reviewed

Bayasula, Iwase A, Kiyono T, Takikawa S, Goto M, Nakamura T, Nagatomo Y, Nakahara T, Kotani T, Kobayashi H, Kondo M, Manabe S, Kikkawa F

Endocrinology   Vol. 153 ( 6 ) page： 2851-60   2012.6

Fertility and pregnancy-associated ß-cell proliferation in mice deficient in proglucagon-derived peptides. Reviewed

  Vol. 7 ( 8 ) page： e43745   2012

The loss of endoglin promotes the invasion of extravillous trophoblasts. Reviewed

Mano Y, Kotani T, Shibata K, Matsumura H, Tsuda H, Sumigama S, Yamamoto E, Iwase A, Senga T, Kikkawa F

Endocrinology   Vol. 152 ( 11 ) page： 4386-94   2011.11

Maternal mental disorders and pregnancy outcomes: a clinical study in a Japanese population. Reviewed

Hironaka M, Kotani T, Sumigama S, Tsuda H, Mano Y, Hayakawa H, Tanaka S, Ozaki N, Tamakoshi K, Kikkawa F

The journal of obstetrics and gynaecology research   Vol. 37 ( 10 ) page： 1283-9   2011.10

Successful fertility management of a patient with factor V deficiency: planned transfusion of fresh frozen plasma under infertility treatment. Reviewed

Iwase A, Goto M, Manabe S, Hirokawa W, Kobayashi H, Nakahara T, Takikawa S, Kotani T, Sumigama S, Tsuda H, Nakayama T, Suzuki N, Matsushita T, Kikkawa F

Fertility and sterility   Vol. 95 ( 6 ) page： 2124.e5-7   2011.5

Amniotic lamellar body counts can predict the occurrence of respiratory distress syndrome as well as transient tachypnea of the newborn (TTN). Reviewed

Tsuda H, Takahashi Y, Iwagaki S, Uchida Y, Kawabata I, Hayakawa M, Sumigama S, Hayakawa H, Kotani T, Kikkawa F

Journal of perinatal medicine   Vol. 39 ( 3 ) page： 245-50   2011.5

Intra-amniotic infection increases amniotic lamellar body count before 34 weeks of gestation. Reviewed

Tsuda H, Takahashi Y, Iwagaki S, Kawabata I, Hayakawa H, Kotani T, Shibata K, Kikkawa F

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians   Vol. 23 ( 10 ) page： 1230-6   2010.10

Elevated levels of aldosterone in the amniotic fluid was observed in two cases of congenital mesoblastic nephroma. Reviewed

Kotani T, Sumigama S, Hayakawa H, Mano Y, Tsuda H, Sugiyama C, Kawachi F, Hironaka M, Kato T, Kaneko K, Hayakawa M, Kikkawa F.

Ultrasound Obstet Gynecol.   Vol. 36 ( 2 ) page： 256-8   2010.8

Histamine stimulates interleukin-6 production through histamine H1 receptors in human amnion cells. Reviewed

Morimitsu A, Sumigama S, Kotani T, Mano Y, Suzuki K, Araki-Taguchi M, Yamamoto E, Hayakawa H, Okada M, Itakura A, Kikkawa F

Gynecologic and obstetric investigation   Vol. 69 ( 1 ) page： 67-72   2010

*Activator protein-2 impairs the invasion of a human extravillous trophoblast cell line Reviewed

Kotani T, Iwase A, Ino K, Sumigama S, Yamamoto E, Hayakawa H, Nagasaka T, Itakura A, Nomura S, Kikkawa F

Endocrinology   Vol. 150 ( 9 ) page： 4376-4385   2009.9

Placenta previa increta/percreta in Japan: a retrospective study of ultrasound findings, management and clinical course. Reviewed

Sumigama S, Itakura A, Ota T, Okada M, Kotani T, Hayakawa H, Yoshida K, Ishikawa K, Hayashi K, Kurauchi O, Yamada S, Nakamura H, Matsusawa K, Sakakibara K, Ito M, Kawai M, Kikkawa F

The journal of obstetrics and gynaecology research   Vol. 33 ( 5 ) page： 606-11   2007.10

Placental leucine aminopeptidase might regulate the effects of oxytocin with resolution in endothelial cells. Reviewed

Sano M, Itakura A, Ito M, Takeuchi M, Okada M, Kotani T, Mizutani S, Kikkawa F

Medical science monitor : international medical journal of experimental and clinical research   Vol. 11 ( 7 ) page： BR195-9   2005.7

【産婦人科における素朴な疑問と解説(2)産科編】Rh式血液型不適合妊娠よりずっと頻度が高いABO式血液型不適合妊娠でトラブルが少ないのはなぜ?(解説)

田野翔　小谷友美（ Role： Joint author）

産科と婦人科  2022.11 

【生殖医療の安全性-どんなリスクと留意点があるのか?】受精卵,児・家族への影響　先天性心疾患と循環器系異常(解説)

森本 美仁, 小谷 友美, 加藤 太一

臨床婦人科産科  2022.11 

【見て、聞いて、触って、身体所見から考える妊産褥婦の異常とその対応】帯下が多い、臭う(解説)

松尾聖子　小谷友美（ Role： Joint author）

周産期医学   2022.8 

【子宮内膜症の最新知識-この1冊で重要ポイントを網羅する】周産期予後　子宮内膜症・子宮腺筋症女性における周産期合併症リスクの考察(解説)

小谷友美　牛田貴文（ Role： Joint author）

2022.7 

今日の治療指針私はこう治療している2022

小谷友美（ Role： Contributor ,  妊娠悪阻）

医学書院  2022.1 

胎児超音波診断を活かす-産科医と新生児科医からの情報提供-

小谷友美、伊藤美春（胸腔内疾患　先天性横隔膜ヘルニア）

周産期医学  2021.9 

【周産期の周辺を強化する-プレコンセプションケアと産後ケアの充実に向けて】

小谷友美.（他科と連携したプレコンセプションケアと産後ケア　精神科医/心療内科医・公認心理師との連携　産婦人科から.）

周産期医学  2021.4 

早産児の後遺症発症の減少を目指して～分子状水素を用いた新規治療法の開発～

2014.4 - 2017.3

科学研究費補助金  基盤研究(C)

小谷 友美

妊娠高血圧症候群の病態機序へのスフィンゴシン１リン酸の関与の解明と治療への応用

2008.4

科学研究費補助金  基盤研究（C)　20599006

胎盤形成のメカニズムと異常

2022

母子感染の予防と治療・周産期メンタルヘルス

2022

胎盤形成のメカニズムと異常

2020

母子感染の予防と治療・周産期メンタルヘルス

2020