Updated on 2022/03/16

写真a

 
UMEGAKI, Hiroyuki
 
Organization
Graduate School of Medicine Program in Integrated Medicine Medicine in Growth and Aging Associate professor
Graduate School
Graduate School of Medicine
Undergraduate School
School of Medicine Department of Medicine
Title
Associate professor
Contact information
メールアドレス

Degree 3

  1. mecdical docotor ( 1998.2   Nagoya University ) 

  2. mecdical docotor ( 1998.2   Nagoya University ) 

  3. mecdical docotor ( 1998.2   Nagoya University ) 

Research Areas 1

  1. Others / Others  / 老年科学

Education 1

  1. Nagoya University   Faculty of Medicine

    1984.4 - 1990.3

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    Country: Japan

Professional Memberships 2

  1. 日本臨床栄養代謝学会

    2020.8

  2. 日本臨床栄養学会   評議員

Awards 1

  1. ノバルティス老年医学賞

    2005   日本老年医学会  

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    Country:Japan

 

Papers 303

  1. Clinical characteristics of older adults with hypertension and unrecognized cognitive impairment

    Yamamoto Koichi, Akasaka Hiroshi, Yasunobe Yukiko, Shimizu Atsuya, Nomoto Kenichiro, Nagai Kumiko, Umegaki Hiroyuki, Akasaki Yuichi, Kojima Taro, Kozaki Koichi, Kuzuya Masafumi, Ohishi Mitsuru, Akishita Masahiro, Takami Yoichi, Rakugi Hiromi

    HYPERTENSION RESEARCH     2022.2

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  2. In response to study results concerning the impact of antidepressants in older adults with major depressive disorder relating to frailty.

    Sakai T, Shiroshita A, Momosaki R, Umegaki H

    The journals of gerontology. Series A, Biological sciences and medical sciences     2022.2

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    Language:English  

    DOI: 10.1093/gerona/glac031

    PubMed

  3. Physical Activity and Neurodegeneration in Older Adults: Comment on: "Associations Between Physical Activity, Blood-Based Biomarkers of Neurodegeneration and Cognition in Healthy Older Adults: The MAPT Study"

    Umegaki Hiroyuki

    JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES   Vol. 77 ( 1 ) page: E34 - E35   2022.1

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  4. Short- and long-term effects of different exercise programs on the gait performance of older adults with subjective cognitive decline: A randomized controlled trial

    Fujita Kosuke, Umegaki Hiroyuki, Makino Taeko, Uemura Kazuki, Hayashi Takahiro, Inoue Aiko, Uno Chiharu, Kitada Tomoharu, Huang Chi Hsien, Shimada Hiroyuki, Kuzuya Masafumi

    EXPERIMENTAL GERONTOLOGY   Vol. 156   page: 111590   2021.12

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  5. Active Life for Brain Health: A Narrative Review of the Mechanism Underlying the Protective Effects of Physical Activity on the Brain

    Umegaki Hiroyuki, Sakurai Takashi, Arai Hidenori

    FRONTIERS IN AGING NEUROSCIENCE   Vol. 13   page: 761674   2021.11

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  6. Proliferin-1 Ameliorates Cardiotoxin-Related Skeletal Muscle Repair in Mice

    Goto Hiroki, Inoue Aiko, Piao Limei, Hu Lina, Huang Zhe, Meng Xiangkun, Suzuki Yusuke, Umegaki Hiroyuki, Kuzuya Masafumi, Cheng Xian Wu

    STEM CELLS INTERNATIONAL   Vol. 2021   page: 9202990   2021.11

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  7. Relationships between overactive bladder and cerebral white matter hyperintensity in outpatients at a memory clinic

    Komiya Hitoshi, Umegaki Hiroyuki, Ogama Noriko, Sakurai Takashi, Kuzuya Masafumi

    GERIATRICS & GERONTOLOGY INTERNATIONAL   Vol. 21 ( 11 ) page: 996 - 1002   2021.11

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  8. Association of dehydration with development of dementia among non-demented geriatric outpatients

    Nagae Masaaki, Umegaki Hiroyuki, Suzuki Yusuke, Komiya Hitoshi, Watanabe Kazuhisa, Yamada Yosuke, Kuzuya Masafumi

    GERIATRICS & GERONTOLOGY INTERNATIONAL   Vol. 21 ( 10 ) page: 963 - 964   2021.10

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  9. The Japan-Multimodal Intervention Trial for Prevention of Dementia (J-MINT): The Study Protocol for an 18-Month, Multicenter, Randomized, Controlled Trial

    Sugimoto T., Sakurai Takashi, Akatsu H., Doi T., Fujiwara Y., Hirakawa A., Kinoshita F., Kuzuya M., Lee S., Matsuo K., Michikawa M., Ogawa S., Otsuka R., Sato K., Shimada H., Suzuki H., Suzuki H., Takechi H., Takeda S., Umegaki H., Wakayama S., Arai H.

    JPAD-JOURNAL OF PREVENTION OF ALZHEIMERS DISEASE   Vol. 8 ( 4 ) page: 465 - 476   2021.9

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    Language:Japanese  

    DOI: 10.14283/jpad.2021.29

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  10. Association of verbal fluency test with progression to dementia in non-demented older adults. Invited Reviewed

    Umegaki H, Suzuki Y.

      Vol. 21 ( 9 ) page: 868 - 869   2021.9

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  11. Echo intensity is more useful in predicting hospital-associated complications than conventional sarcopenia-related parameters in acute hospitalized older patients

    Nagae Masaaki, Umegaki Hiroyuki, Yoshiko Akito, Fujita Kosuke, Komiya Hitoshi, Watanabe Kazuhisa, Yamada Yosuke, Kuzuya Masafumi, Leeuwenburgh Christiaan

    EXPERIMENTAL GERONTOLOGY   Vol. 150   page: 111397   2021.7

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  12. The Multi-Domain Intervention Trial in Older Adults With Diabetes Mellitus for Prevention of Dementia in Japan: Study Protocol for a Multi-Center, Randomized, 18-Month Controlled Trial

    Sugimoto Taiki, Araki Atsushi, Fujita Hiroki, Honda Keiko, Inagaki Nobuya, Ishida Takeshi, Kato Junichi, Kishi Minoru, Kobayashi Kazuki, Kouyama Kunichi, Noma Hisashi, Ohishi Mitsuru, Satoh-Asahara Noriko, Shimada Hiroyuki, Sugimoto Kazuhiro, Suzuki Susumu, Takeya Yasushi, Tamura Yoshiaki, Tokuda Haruhiko, Umegaki Hiroyuki, Watada Hirotaka, Yamada Yuichiro, Sakurai Takashi

    FRONTIERS IN AGING NEUROSCIENCE   Vol. 13   page: 680341   2021.7

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  13. Chronic Effects of a Static Stretching Program on Hamstring Strength

    Nakao Sayaka, Ikezoe Tome, Nakamura Masatoshi, Umegaki Hiroki, Fujita Kosuke, Umehara Jun, Kobayashi Takuya, Ibuki Satoko, Ichihashi Noriaki

    JOURNAL OF STRENGTH AND CONDITIONING RESEARCH   Vol. 35 ( 7 ) page: 1924 - 1929   2021.7

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  14. Functional categories based on cognition and activities of daily living predict all-cause mortality in older adults with diabetes mellitus: The Japanese Elderly Diabetes Intervention Trial

    Omura Takuya, Tamura Yoshiaki, Sakurai Takashi, Umegaki Hiroyuki, Iimuro Satoshi, Ohashi Yasuo, Ito Hideki, Araki Atsushi

    GERIATRICS & GERONTOLOGY INTERNATIONAL   Vol. 21 ( 6 ) page: 512 - 518   2021.6

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  15. Effect of Various Exercises on Intrinsic Capacity in Older Adults With Subjective Cognitive Concerns.

    Huang CH, Umegaki H, Makino T, Uemura K, Hayashi T, Kitada T, Inoue A, Shimada H, Kuzuya M

    Journal of the American Medical Directors Association   Vol. 22 ( 4 ) page: 780 - +   2021.4

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jamda.2020.06.048

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  16. Determinants and impact of physical impairment in patient-reported outcomes among older patients with type 2 diabetes mellitus in Japan.

    Araki A, Umegaki H, Sakurai T, Mizuno Y, Miyao M, Imori M, Suzuki S, Cambron-Mellott MJ, Yokote K, Onuma T, Yokono K

    Current medical research and opinion   Vol. 37 ( 3 ) page: 393 - 402   2021.3

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1080/03007995.2020.1846170

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  17. Association of fear of falling with cognitive function and physical activity in older community-dwelling adults

    Umegaki Hiroyuki, Uemura Kazuki, Makino Taeko, Hayashi Takahiro, Cheng Xian Wu, Kuzuya Masafumi

    EUROPEAN GERIATRIC MEDICINE   Vol. 12 ( 1 ) page: 99 - 106   2021.2

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s41999-020-00410-2

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  18. Mild hyponatremia is associated with low skeletal muscle mass, physical function impairment, and depressive mood in the elderly

    Fujisawa Chisato, Umegaki Hiroyuki, Sugimoto Taiki, Samizo Satoshi, Huang Chi Hsien, Fujisawa Haruki, Sugimura Yoshihisa, Kuzuya Masafumi, Toba Kenji, Sakurai Takashi

    BMC GERIATRICS   Vol. 21 ( 1 ) page: 15   2021.1

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  19. Mental Health Status of the Older Adults in Japan During the COVID-19 Pandemic

    Fujita Kosuke, Inoue Aiko, Kuzuya Masafumi, Uno Chiharu, Huang Chi Hsien, Umegaki Hiroyuki, Onishi Joji

    JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION   Vol. 22 ( 1 ) page: 220 - 221   2021.1

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  20. Frequencies and Neuropsychological Characteristics of Errors in the Clock Drawing Test

    Umegaki Hiroyuki, Suzuki Yusuke, Komiya Hitoshi, Watanabe Kazuhisa, Yamada Yosuke, Nagae Masaaki, Kuzuya Masafumi

    JOURNAL OF ALZHEIMERS DISEASE   Vol. 82 ( 3 ) page: 1291 - 1300   2021

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  21. Effects of Aerobic, Resistance, or Combined Exercise Training Among Older Adults with Subjective Memory Complaints: A Randomized Controlled Trial

    Makino Taeko, Umegaki Hiroyuki, Ando Masahiko, Cheng Xian Wu, Ishida Koji, Akima Hiroshi, Oshida Yoshiharu, Yoshida Yasuko, Uemura Kazuki, Shimada Hiroyuki, Kuzuya Masafumi

    JOURNAL OF ALZHEIMERS DISEASE   Vol. 82 ( 2 ) page: 701 - 717   2021

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  22. Cross-Sectional Examination of Homocysteine Levels with Sarcopenia and Its Components in Memory Clinic Outpatients

    Yamada Yosuke, Umegaki Hiroyuki, Kinoshita Fumie, Huang Chi Hsien, Sugimoto Taiki, Fujisawa Chisato, Komiya Hitoshi, Watanabe Kazuhisa, Nagae Masaaki, Kuzuya Masafumi, Sakurai Takashi

    JOURNAL OF ALZHEIMERS DISEASE   Vol. 82 ( 3 ) page: 975 - 984   2021

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  23. Associations Between Polypharmacy and Gait Speed According to Cognitive Impairment Status: Cross-Sectional Study in a Japanese Memory Clinic

    Watanabe Kazuhisa, Umegaki Hiroyuki, Sugimoto Taiki, Fujisawa Chisato, Komiya Hitoshi, Nagae Masaaki, Yamada Yosuke, Kuzuya Masafumi, Sakurai Takashi, Stirland Lucy

    JOURNAL OF ALZHEIMERS DISEASE   Vol. 82 ( 3 ) page: 1115 - 1122   2021

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  24. HOme-based Longitudinal Investigation of the multidiSciplinary Team Integrated Care (HOLISTIC): protocol of a prospective nationwide cohort study.

    Liao JY, Chen PJ, Wu YL, Cheng CH, Yu SJ, Huang CH, Li CM, Wang YW, Zhang KP, Liu IT, Umegaki H, Hamano J, Mori M, Petersen I, Sampson EL, Hsiung CA

    BMC geriatrics   Vol. 20 ( 1 ) page: 511   2020.12

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1186/s12877-020-01920-1

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  25. Effect of various exercises on frailty among older adults with subjective cognitive concerns: a randomised controlled trial.

    Huang CH, Umegaki H, Makino T, Uemura K, Hayashi T, Kitada T, Inoue A, Shimada H, Kuzuya M

    Age and ageing   Vol. 49 ( 6 ) page: 1011 - 1019   2020.11

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1093/ageing/afaa086

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  26. Chronic Dehydration in Nursing Home Residents.

    Nagae M, Umegaki H, Onishi J, Huang CH, Yamada Y, Watanabe K, Komiya H, Kuzuya M

    Nutrients   Vol. 12 ( 11 )   2020.11

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/nu12113562

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  27. Association of the Qualitative Clock Drawing Test with Progression to Dementia in Non-Demented Older Adults.

    Umegaki H, Suzuki Y, Yamada Y, Komiya H, Watanabe K, Nagae M, Kuzuya M

    Journal of clinical medicine   Vol. 9 ( 9 ) page: 2850   2020.9

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    DOI: 10.3390/jcm9092850

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  28. Association of polypharmacy with decline in quality of life in mild cognitive impairment and mild dementia

    Umegaki Hiroyuki

    GERIATRICS & GERONTOLOGY INTERNATIONAL   Vol. 20 ( 9 ) page: 840 - 842   2020.9

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/ggi.13988

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  29. Association Between Sarcopenia and Quality of Life in Patients with Early Dementia and Mild Cognitive Impairment.

      Vol. 76 ( 1 ) page: 435-442   2020.5

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    DOI: 10.3233/JAD-200169

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  30. A Study on the Relationship between Cognitive Performance, Hearing Impairment, and Frailty in Older Adults.

    Bonfiglio V, Umegaki H, Kuzuya M

    Dementia and geriatric cognitive disorders   Vol. 49 ( 2 ) page: 156-162   2020.4

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    DOI: 10.1159/000507214

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  31. Combined Impact of Physical Frailty and Social Isolation on Rate of Falls in Older Adults

    Hayashi T., Umegaki Hiroyuki, Makino T., Huang C. H., Inoue A., Shimada H., Kuzuya M.

    JOURNAL OF NUTRITION HEALTH & AGING   Vol. 24 ( 3 ) page: 312 - 318   2020.3

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s12603-020-1316-5

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  32. Falls in community-dwelling prefrail older adults

    Umegaki Hiroyuki, Makino Taeko, Uemura Kazuki, Shimada Hiroyuki, Cheng Xian Wu, Dodge Hiroko, Kuzuya Masafumi

    HEALTH & SOCIAL CARE IN THE COMMUNITY   Vol. 28 ( 1 ) page: 110 - 115   2020.1

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/hsc.12845

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  33. Assessing the association between optimal energy intake and all-cause mortality in older patients with diabetes mellitus using the Japanese Elderly Diabetes Intervention Trial

    Omura Takuya, Tamura Yoshiaki, Yamaoka Takuya, Yoshimura Yukio, Sakurai Takashi, Umegaki Hiroyuki, Kamada Chiemi, Iimuro Satoshi, Ohashi Yasuo, Ito Hideki, Araki Atsushi

    GERIATRICS & GERONTOLOGY INTERNATIONAL   Vol. 20 ( 1 ) page: 59 - 65   2020.1

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/ggi.13820

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  34. [Malignant lymphoma with IgG4-related disease arising in a very elderly man].

    Nagae M, Onishi J, Umegaki H, Kuzuya M

    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics   Vol. 57 ( 3 ) page: 321-326   2020

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    DOI: 10.3143/geriatrics.57.321

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  35. Cathepsin S-Mediated Negative Regulation of Wnt5a/SC35 Activation Contributes to Ischemia-Induced Neovascularization in Aged Mice

    Xu Wenhu, Yu Chenglin, Piao Limei, Inoue Aiko, Wang Hailong, Meng Xiangkun, Li Xiang, Cui Lan, Umegaki Hiroyuki, Shi Guo-Ping, Murohara Toyoaki, Kuzuya Masafumi, Cheng Xian Wu

    CIRCULATION JOURNAL   Vol. 83 ( 12 ) page: 2537 - +   2019.12

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    DOI: 10.1253/circj.CJ-19-0325

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  36. Plasma orexin-A levels in patients with delirium.

    Nakashima H, Umegaki H, Yanagawa M, Komiya H, Watanabe K, Kuzuya M

    Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society   Vol. 19 ( 6 ) page: 628-630   2019.11

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    DOI: 10.1111/psyg.12444

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  37. Association between dysphagia risk and unplanned hospitalization in older patients receiving home medical care

    Watanabe Kazuhisa, Umegaki Hiroyuki, Huang Chi-Hsien, Arakawa Martins Beatriz, Asai Atsushi, Kanda Shigeru, Nomura Hideki, Kuzuya Masafumi

    GERIATRICS & GERONTOLOGY INTERNATIONAL   Vol. 19 ( 10 ) page: 977 - 981   2019.10

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/ggi.13753

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  38. Quality of life in cognitively impaired older adults

    Bonfiglio Viviana, Umegaki Hiroyuki, Kuzuya Masafumi

    GERIATRICS & GERONTOLOGY INTERNATIONAL   Vol. 19 ( 10 ) page: 999 - 1005   2019.10

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/ggi.13759

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  39. Higher and Lower Muscle Echo Intensity in Elderly Individuals Is Distinguished by Muscle Size, Physical Performance and Daily Physical Activity.

    Yoshiko Akito, Natsume Yukie, Makino Taeko, Hayashi Takahiro, Umegaki Hiroyuki, Yoshida Yasuko, Cheng Xian Wu, Kuzuya Masafumi, Ishida Koji, Koike Teruhiko, Oshida Yoshiharu, Akima Hiroshi

    ULTRASOUND IN MEDICINE AND BIOLOGY   Vol. 45 ( 9 ) page: 2372 - 2380   2019.9

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.ultrasmedbio.2019.05.029

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  40. Plasma orexin-A-like immunoreactivity levels and renal function in patients in a geriatric ward

    Nakashima Hirotaka, Umegaki Hiroyuki, Yanagawa Madoka, Komiya Hitoshi, Watanabe Kazuhisa, Kuzuya Masafumi

    PEPTIDES   Vol. 118   page: 170092   2019.8

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    DOI: 10.1016/j.peptides.2019.170092

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  41. Relationship between blood coagulability and sense of burden among caregivers of patients with dementia

    Hirano Akemi, Suzuki Yusuke, Umegaki Hiroyuki, Hayashi Toshio, Ina Koichiro, Onishi Joji, Hasegawa Jun, Kuzuya Masafumi

    GERIATRICS & GERONTOLOGY INTERNATIONAL   Vol. 19 ( 8 ) page: 804 - 808   2019.8

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/ggi.13721

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  42. Polypharmacy and gait speed in individuals with mild cognitive impairment

    Umegaki Hiroyuki, Yanagawa Madoka, Komiya Hitoshi, Matsubara Masaki, Fujisawa Chisato, Suzuki Yusuke, Kuzuya Masafumi

    GERIATRICS & GERONTOLOGY INTERNATIONAL   Vol. 19 ( 8 ) page: 730 - 735   2019.8

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/ggi.13688

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  43. Cathepsin S Deficiency Mitigated Chronic Stress-Related Neointimal Hyperplasia in Mice

    Wang Hailong, Meng Xiangkun, Piao Limei, Inoue Aiko, Xu Wenhu, Yu Chenglin, Nakamura Kae, Hu Lina, Sasaki Takeshi, Wu Hongxian, Unno Kazumasa, Umegaki Hiroyuki, Murohara Toyoaki, Shi Guo-Ping, Kuzuya Masafumi, Cheng Xian Wu

    JOURNAL OF THE AMERICAN HEART ASSOCIATION   Vol. 8 ( 14 ) page: e011994   2019.7

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1161/JAHA.119.011994

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  44. Response to the comments on "Sarcopenia and depressive mood in older adults"

    Hayashi Takahiro, Umegaki Hiroyuki, Makino Taeko, Cheng Xian W., Shimada Hiroyuki, Kuzuya Masafumi

    GERIATRICS & GERONTOLOGY INTERNATIONAL   Vol. 19 ( 7 ) page: 690 - 691   2019.7

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/ggi.13713

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  45. Association between sarcopenia and depressive mood in urban-dwelling older adults: A cross-sectional study

    Hayashi Takahiro, Umegaki Hiroyuki, Makino Taeko, Cheng Xian W., Shimada Hiroyuki, Kuzuya Masafumi

    GERIATRICS & GERONTOLOGY INTERNATIONAL   Vol. 19 ( 6 ) page: 508 - 512   2019.6

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/ggi.13650

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  46. Prevalence and risk factors of constipation and pollakisuria among older home-care patients

    Komiya Hitoshi, Umegaki Hiroyuki, Asai Atsushi, Kanda Shigeru, Maeda Keiko, Nomura Hideki, Kuzuya Masafumi

    GERIATRICS & GERONTOLOGY INTERNATIONAL   Vol. 19 ( 4 ) page: 277 - 281   2019.4

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/ggi.13610

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  47. [Diabetes Mellitus and Dementia].

    Umegaki H

    Brain and nerve = Shinkei kenkyu no shinpo   Vol. 71 ( 4 ) page: 409-414   2019.4

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    DOI: 10.11477/mf.1416201286

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  48. Association of Glucose Fluctuations with Sarcopenia in Older Adults with Type 2 Diabetes Mellitus

    Ogama Noriko, Sakurai Takashi, Kawashima Shuji, Tanikawa Takahisa, Tokuda Haruhiko, Satake Shosuke, Miura Hisayuki, Shimizu Atsuya, Kokubo Manabu, Niida Shumpei, Toba Kenji, Umegaki Hiroyuki, Kuzuya Masafumi

    JOURNAL OF CLINICAL MEDICINE   Vol. 8 ( 3 ) page: 319   2019.3

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/jcm8030319

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  49. Potentially inappropriate medications according to STOPP-J criteria and risks of hospitalization and mortality in elderly patients receiving home-based medical services

    Huang Chi-Hsien, Umegaki Hiroyuki, Watanabe Yuuki, Kamitani Hiroko, Asai Atushi, Kanda Shigeru, Nomura Hideki, Kuzuya Masafumi

    PLOS ONE   Vol. 14 ( 2 ) page: e0211947   2019.2

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1371/journal.pone.0211947

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  50. Complaint of poor night sleep is correlated with physical function impairment in mild Alzheimer's disease patients

    Fujisawa Chisato, Umegaki Hiroyuki, Nakashima Hirotaka, Kuzuya Masafumi, Toba Kenji, Sakurai Takashi

    GERIATRICS & GERONTOLOGY INTERNATIONAL   Vol. 19 ( 2 ) page: 171 - 172   2019.2

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/ggi.13593

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  51. Change in quality of life and potentially associated factors in patients receiving home-based primary care: a prospective cohort study

    Huang Chi-Hsien, Umegaki Hiroyuki, Kamitani Hiroko, Asai Atushi, Kanda Shigeru, Maeda Keiko, Nomura Hideki, Kuzuya Masafumi

    BMC GERIATRICS   Vol. 19 ( 1 ) page: 21   2019.1

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1186/s12877-019-1040-3

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  52. Potentially Inappropriate Medications and Polypharmacy: A Study of Older People with Mild Cognitive Impairment and Mild Dementia.

    Bonfiglio V, Umegaki H, Kuzuya M

      Vol. 71 ( 3 ) page: 889-897   2019

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  53. Potentially Inappropriate Medications and Polypharmacy: A Study of Older People with Mild Cognitive Impairment and Mild Dementia

    Bonfiglio Viviana, Umegaki Hiroyuki, Kuzuya Masafumi

    JOURNAL OF ALZHEIMERS DISEASE   Vol. 71 ( 3 ) page: 889 - 897   2019

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    DOI: 10.3233/JAD-190284

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  54. Postprandial Hyperglycemia Is Associated With White Matter Hyperintensity and Brain Atrophy in Older Patients With Type 2 Diabetes Mellitus

    Ogama Noriko, Sakurai Takashi, Kawashima Shuji, Tanikawa Takahisa, Tokuda Haruhiko, Satake Shosuke, Miura Hisayuki, Shimizu Atsuya, Kokubo Manabu, Niida Shumpei, Toba Kenji, Umegaki Hiroyuki, Kuzuya Masafumi

    FRONTIERS IN AGING NEUROSCIENCE   Vol. 10   page: 273   2018.9

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.3389/fnagi.2018.00273

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  55. Maximum gait speed is associated with a wide range of cognitive functions in Japanese older adults with a Clinical Dementia Rating of 0.5. Reviewed

    Umegaki H, Makino T, Yanagawa M, Nakashima H, Kuzuya M, Sakurai T, Toba K.

    Geriatr Gerontol Int.   Vol. 18 ( 9 ) page: 1323-1329   2018.9

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    DOI: 10.1111/ggi.13464. Epub 2018 Jul 6.

  56. Diabetes-related cognitive dysfunction: Hyperglycemia in the early stage might be a key? Reviewed

    Umegaki H

    J Diabetes Investig.   Vol. 9 ( 5 ) page: 1019-1021   2018.9

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  57. Association between insulin resistance and objective measurement of physical activity in community-dwelling older adults without diabetes mellitus

    Umegaki Hiroyuki, Makino Taeko, Uemura Kazuki, Shimada Hiroyuki, Hayashi Takahiro, Cheng Xian Wu, Kuzuya Masafumi

    DIABETES RESEARCH AND CLINICAL PRACTICE   Vol. 143   page: 267 - 274   2018.9

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.diabres.2018.07.022

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  58. Maximum gait speed is associated with a wide range of cognitive functions in Japanese older adults with a Clinical Dementia Rating of 0.5

    Umegaki Hiroyuki, Makino Taeko, Yanagawa Madoka, Nakashima Hirotaka, Kuzuya Masafumi, Sakurai Takashi, Toba Kenji

    GERIATRICS & GERONTOLOGY INTERNATIONAL   Vol. 18 ( 9 ) page: 1323 - 1329   2018.9

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    DOI: 10.1111/ggi.13464

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  59. Diabetes-related cognitive dysfunction: Hyperglycemia in the early stage might be a key?

    Umegaki Hiroyuki

    JOURNAL OF DIABETES INVESTIGATION   Vol. 9 ( 5 ) page: 1019 - 1021   2018.9

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    DOI: 10.1111/jdi.12808

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  60. Correlation between regional cerebral blood flow and body composition in cognitively healthy elderly women: a SPECT study. Reviewed

    Fujisawa C, Umegaki H, Kato T, Nakashima H, Kuzuya M, Ito K, Toba K, Sakurai T

    Geriatr Gerontol Int   Vol. 18 ( 8 ) page: 1303-1304   2018.8

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    DOI: 10.1111/ggi.13444.

  61. Correlation between regional cerebral blood flow and body composition in healthy older women: A single-photon emission computed tomography study

    Fujisawa Chisato, Umegaki Hiroyuki, Kato Takashi, Nakashima Hirotaka, Kuzuya Masafumi, Ito Kengo, Toba Kenji, Sakurai Takashi

    GERIATRICS & GERONTOLOGY INTERNATIONAL   Vol. 18 ( 8 ) page: 1303 - 1304   2018.8

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    DOI: 10.1111/ggi.13444

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  62. Association between insulin resistance and objective measurement of physical activity in community-dwelling older adults without diabetes mellitus. Reviewed

    Umegaki H, Makino T, Uemura K, Shimada H, Hayashi T, Cheng X W, Kuzuya M.

    Diabetes Res Clin Pract   Vol. 143   page: 267   2018.7

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  63. 基礎・臨床研究の最新動向 Ⅴ.高齢者へのアプローチ 高齢者病態の特徴

    梅垣宏行

    日本臨床   Vol. 76 ( 5 ) page: 299~304   2018.6

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  64. Frontal white matter hyperintensity is associated with verbal aggressiveness in elderly women with alzheimer disease and amnestic nils cognitive impairment. Reviewed

    Ogama N, Sakurai T, Saji N, Nakai T, Niida S, Toba K, Umegaki H, Kuzuya M

    Dement Geriatr Cogn Disord Extra   Vol. 8 ( 1 ) page: 138-150   2018.4

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  65. Cilostazol for the prevention of pneumonia: a systematic review. Reviewed

    Nakashima H, Watanabe K, Umegaki H, Suzuki Y, Kuzuya M.

    Pneumonia   Vol. 10   page: 3   2018.4

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  66. Cilostazol for the prevention of pneumonia: a systematic review

    Nakashima Hirotaka, Watanabe Kazuhisa, Umegaki Hiroyuki, Suzuki Yusuke, Kuzuya Masafumi

    PNEUMONIA   Vol. 10   page: 3   2018.4

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    DOI: 10.1186/s41479-018-0046-5

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  67. Cognitive Dysfunction in Urban-Community Dwelling Prefrail Older Subjects. Reviewed

    Umegaki H, Makino T, Shimada H, Hayashi T, Wu Cheng X, Kuzuya M.

    J Nutr Health Aging   Vol. 22 ( 4 ) page: 549-554   2018.4

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  68. 高齢者医療ハンドブック-高齢者医療におけるダイバーシティへの対応】(第II章)高齢者と老年症候群 やせ(解説/特集)

    梅垣宏行

    ㈱南江堂   Vol. 121 ( 4 ) page: 645-648   2018.4

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  69. Cognitive Dysfunction in Urban-Community Dwelling Prefrail Older Subjects

    Umegaki H., Makino T., Shimada H., Hayashi T., Cheng X. Wu, Kuzuya M.

    JOURNAL OF NUTRITION HEALTH & AGING   Vol. 22 ( 4 ) page: 549-554   2018.4

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    DOI: 10.1007/s12603-018-1017-5

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  70. 病気とくすり2018 基礎と実践Expert’s Guide 精神・中枢神経の病気とくすり 認知症

    梅垣宏行、渡邉雄貴、山田清文

    薬局   Vol. 69 ( 4 ) page: 738-746   2018.3

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  71. Objectively measured physical activity and cognitive function in urban-dwelling older subjects Reviewed

    Umegaki H, Makino T, Uemura K, Shimada H, Cheng X W, Kuzuya M.

    Geriatr Gerontol Int   Vol. 18 ( 6 ) page: 922-928   2018.2

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    DOI: 10.1111/ggi.13284

  72. Cathepsin K activity controls cardiotoxin-induced skeletal muscle repair in mice. Reviewed

    Ogasawara S, Cheng XW, Inoue A, Hu L, Piao L, Yu C, Goto H, Xu W, Zhao G, Lei Y, Yang G, Kimura K, Umegaki H, Shi GP, Kuzuya M.

    J Cachexia Sarcopenia Muscle   Vol. 9 ( 1 ) page: 160–175   2018.2

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  73. 高齢者の総合機能評価

    梅垣宏行,葛谷雅文

    救急医学   Vol. 42 ( 2 ) page: 204~209   2018.2

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  74. Cathepsin K activity controls cardiotoxin-induced skeletal muscle repair in mice

    Ogasawara Shinyu, Cheng Xian Wu, Inoue Aiko, Hu Lina, Piao Limei, Yu Chenglin, Goto Hiroki, Xu Wenhu, Zhao Guangxian, Lei Yanna, Yang Guang, Kimura Kaoru, Umegaki Hiroyuki, Shi Guo-Ping, Kuzuya Masafumi

    JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE   Vol. 9 ( 1 ) page: 160 - 175   2018.2

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    DOI: 10.1002/jcsm.12248

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  75. Factors associated with polypharmacy in elderly home-care patients

    Komiya H, Umegaki H, Atsushi A, Kanda S, Maeda K, Shimojima T, Nomura H, Kuzuya M

    Geriatr Gerontol Int.   Vol. 18 ( 1 ) page: 33-41   2018.1

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  76. 在宅医療を受ける高齢者のQOL (quality of life) 評価票における本人と介護者による代理評価の回答の一致性の検討

    紙谷博子、梅垣宏行、岡本和士、神田茂、浅井真嗣、下島卓弥、野村秀樹、服部文子、木股貴哉、鈴木裕介、大島浩子、葛谷雅文

    日本老年医学会雑誌   Vol. 55 ( 1 ) page: 98-105   2018.1

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  77. 脳波データを用いたMMSEスコアの推定に関する検討

    三輪晃暉、高倉健太郎、吉川大弘、古橋 武、寶珠山 稔、牧野多恵子、柳川まどか、鈴木裕介、梅垣宏行、葛谷雅文

    信学技報   Vol. 117 ( 417 ) page: 信学技報   2018.1

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  78. Effects of a Thermal Agent and Physical Activity on Muscle Tendon Stiffness, as Well as the Effects Combined With Static Stretching

    Fujita Kosuke, Nakamura Masatoshi, Umegaki Hiroki, Kobayashi Takuya, Nishishita Satoru, Tanaka Hiroki, Ibuki Satoko, Ichihashi Noriaki

    JOURNAL OF SPORT REHABILITATION   Vol. 27 ( 1 ) page: 66-72   2018.1

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    DOI: 10.1123/jsr.2015-0165

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  79. Factors associated with polypharmacy in elderly home-care patients

    Komiya Hitoshi, Umegaki Hiroyuki, Asai Atsushi, Kanda Shigeru, Maeda Keiko, Shimojima Takuya, Nomura Hideki, Kuzuya Masafumi

    GERIATRICS & GERONTOLOGY INTERNATIONAL   Vol. 18 ( 1 ) page: 33 - 41   2018.1

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    DOI: 10.1111/ggi.13132

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  80. Study on Estimation of MMSE Score by Using the Latency of P300 and Alpha Wave

    Miwa Koki, Yoshikawa Tomohiro, Furuhashi Takeshi, Hoshiyama Minoru, Makino Taeko, Yanagawa Madoka, Suzuki Yusuke, Umegaki Hiroyuki, Kuzuya Masafumi

    2018 JOINT 10TH INTERNATIONAL CONFERENCE ON SOFT COMPUTING AND INTELLIGENT SYSTEMS (SCIS) AND 19TH INTERNATIONAL SYMPOSIUM ON ADVANCED INTELLIGENT SYSTEMS (ISIS)     page: 195-199   2018

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    DOI: 10.1109/SCIS-ISIS.2018.00041

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  81. Frontal White Matter Hyperintensity Is Associated with Verbal Aggressiveness in Elderly Women with Alzheimer Disease and Amnestic Mild Cognitive Impairment

    Ogama Noriko, Sakurai Takashi, Saji Naoki, Nakai Toshiharu, Niida Shumpei, Toba Kenji, Umegaki Hiroyuki, Kuzuya Masafumi

    DEMENTIA AND GERIATRIC COGNITIVE DISORDERS EXTRA   Vol. 8 ( 1 ) page: 138 - 150   2018

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    DOI: 10.1159/000486826

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  82. [Agreement in the responses to self-reported and proxy-reported versions of QOL-HC: a new quality-of-life scale for patients receiving home-based medical care].

    Kamitani H, Umegaki H, Okamoto K, Kanda S, Asai A, Shimojima T, Nomura H, Hattori A, Kimata T, Suzuki Y, Ohshima H, Kuzuya M

    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics   Vol. 55 ( 1 ) page: 98-105   2018

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    DOI: 10.3143/geriatrics.55.98

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  83. 高齢糖尿病患者における血糖コントロールの現状

    服部孝二、梅垣宏行、小宮 仁、渡邊一久、葛谷雅文

    日老医誌   Vol. 54   page: 531-536   2017.12

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  84. Authors' reply to the letter by Esra et al

    Umegaki H, Nonogaki Z, Makino T, Suzuki Y, Kuzuya M

    Geriatr Gerontol Int.   Vol. 17 ( 11 ) page: 2284-2285   2017.11

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  85. 高齢者とインスリン分泌促進薬

    梅垣宏行

    糖尿病の最新治療   Vol. 9 ( 1 ) page: 32-36   2017.11

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  86. Ⅲ.高齢者糖尿病の管理・治療上の留意点 3.薬物療法 (2)経口血糖降下薬使用時の留意点

    梅垣宏行

    高齢者糖尿病   Vol. 75 ( 11 ) page: 1689   2017.11

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  87. Authors' reply to the letter by Esra et al

    Umegaki Hiroyuki, Nonogaki Zen, Makino Taeko, Suzuki Yusuke, Kuzuya Masafumi

    GERIATRICS & GERONTOLOGY INTERNATIONAL   Vol. 17 ( 11 ) page: 2284 - 2285   2017.11

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    DOI: 10.1111/ggi.13105

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  88. (質疑応答)塩酸ドネペジルの認知症症状の進行抑制効果とは?

    梅垣宏行

    日本医事新報     page: 59   2017.10

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  89. Factors associated with unexpected admissions and mortality among low-functioning older patients receiving home medical care.

    Umegaki H, Asai A, Kanda S, Maeda K, Shimojima T, Nomura H, Kuzuya M.

    Geriatr Gerontol Int   Vol. 17 ( 10 ) page: 1623-1627   2017.10

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    DOI: 10.1111/ggi.12943

  90. 認知機能の評価と対応

    梅垣宏行 

    月刊糖尿病   Vol. 9 ( 9 ) page: 28-33   2017.9

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  91. Low intakes of carotene, vitamin B2, pantothenate, and calcium predict cognitive decline among elderly patients with diabetes mellitus: the Japanese Elderly Diabetes Intervention Trial Research Group.

    Araki A, Yoshimura Y, Sakurai T, Umegaki H, Kamada C, Iimuro S, Ohashi Y, Ito H; Japanese Elderly Diabetes Intervention Trial Research Group.

    Geriatr Gerontol Int.   Vol. 17 ( 8 ) page: 1168-1175   2017.8

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    DOI: 10.1111/ggi.12843

  92. 高齢者糖尿病のインスリンの使用法

    梅垣宏行

    Geriatric Med.   Vol. 55 ( 8 ) page: 905-908   2017.8

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  93. 高齢者糖尿病の血糖管理目標について

    梅垣宏行

    Medical Practice   Vol. 34 ( 6 ) page: 1044   2017.6

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  94. 高齢者糖尿病患者の食事・運動療法がわからない!?

    梅垣宏行、葛谷雅文

    Diabetes Strategy   Vol. 7 ( 5 ) page: 75-79   2017.5

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  95. Physical Function Differences Between the Stages From Normal Cognition to Moderate Alzheimer Disease.

    Fujisawa C, Umegaki H, Okamoto K, Nakashima H, Kuzuya M, Toba K, Sakurai T.

    J Am Med Dir Assoc.   Vol. 18 ( 4 ) page: 368.e9-368.e15   2017.4

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  96. Physical Function Differences Between the Stages From Normal Cognition to Moderate Alzheimer Disease

    Fujisawa Chisato, Umegaki Hiroyuki, Okamoto Kazushi, Nakashima Hirotaka, Kuzuya Masafumi, Toba Kenji, Sakurai Takashi

    JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION   Vol. 18 ( 4 ) page: 368.e9 - 368.e15   2017.4

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    DOI: 10.1016/j.jamda.2016.12.079

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  97. The associations among insulin resistance, hyperglycemia, physical performance, diabetes mellitus, and cognitive function in relatively healthy older adults with subtle cognitive dysfunction.

    Umegaki H, Makino T, Uemura K, Shimada H, Hyashi T, Cheng XY, Kuzuya M.

    Front aging neurosci.     page: doi: 10.3389/fnagi.2017.00072.   2017.3

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  98. The Associations among Insulin Resistance, Hyperglycemia, Physical Performance, Diabetes Mellitus, and Cognitive Function in Relatively Healthy Older Adults with Subtle Cognitive Dysfunction

    Umegaki Hiroyuki, Makino Taeko, Uemura Kazuki, Shimada Hiroyuki, Hayashi Takahiro, Cheng Xian Wu, Kuzuya Masafumi

    FRONTIERS IN AGING NEUROSCIENCE   Vol. 9   page: 72   2017.3

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    DOI: 10.3389/fnagi.2017.00072

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  99. Impact of frontal white matter hyperintensity on instrumental activities of daily living in elderly women with Alzheimer disease and amnestic mild cognitive impairment.

    Ogama N, Sakurai T, Nakai T, Niida S, Saji N, Toba K, Umegaki H, Kuzuya M.

    PLoS One.   Vol. 12 ( 3 ) page: e0172484   2017.3

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  100. Impact of frontal white matter hyperintensity on instrumental activities of daily living in elderly women with Alzheimer disease and amnestic mild cognitive impairment

    Ogama Noriko, Sakurai Takashi, Nakai Toshiharu, Niida Shumpei, Saji Naoki, Toba Kenji, Umegaki Hiroyuki, Kuzuya Masafumi

    PLOS ONE   Vol. 12 ( 3 ) page: e0172484   2017.3

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    DOI: 10.1371/journal.pone.0172484

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  101. Development and validation of a new quality of life scale for patients receiving home-based medical care: The Observational Study of Nagoya Elderly with Home Medical Care.

    Kamitani H, Umegaki H, Okamoto K, Kanda S, Asai A, Maeda K, Nomura H, Shimojima T, Suzuki Y, Ohshima H, Kuzuya M.

    Geriatr Gerontol Int   Vol. 17 ( 3 ) page: 440-448   2017.3

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    DOI: 10.1111/ggi.12735

  102. Association of blood pressure and cognitive decline in older adults with diabetes mellitus during a 9-year observational study.

    Umegaki H, Kawamura T, Umemura T, Kawano N

    Geriatr Gerontol Int.   Vol. 17 ( 3 ) page: 514 - 515   2017.3

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    DOI: 10.1111/ggi.12886

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  103. 精神・神経系の病気とくすり 中枢系疾患認知症(解説/特集)

    梅垣宏行、渡邉雄貴、山田清文

    薬局   Vol. 68 ( 4 ) page: 740-748   2017.3

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  104. Association of blood pressure and cognitive decline in older adults with diabetes mellitus during a 9-year observational study

    Umegaki Hiroyuki, Kawamura Takahiko, Umemura Toshitaka, Kawano Naoko

    GERIATRICS & GERONTOLOGY INTERNATIONAL   Vol. 17 ( 3 ) page: 514-515   2017.3

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  105. Randomized,Double-blind Placebo-controlled Multicenter Trial of Yokukansan for Neuropsychiatric Symptoms in Alzheimer's Disease.

    Furukawa K, Tomita N, Uematsu D, Okahara K, Shimada H, Ikeda M, Matsui T, Kozaki K, Fujii M, Ogawa T, Umegaki H, Urakami K, Nomura H, Kobayashi N, Nakanishi A, Washimi Y, Yonezawa H, Takahashi S, Kubota M, Wakutani Y, Ito D, Sasaki T, Matsubara E, Une K, Ishiki A, Yahagi Y, Shoji M, Sato H, Terayama Y, Kuzuya M, Araki N, Kodama M, Yamaguchi T, Arai H.

    Geriatr Gerontol Int   Vol. 17 ( 2 ) page: 211-218   2017.2

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    DOI: 10.1111/ggi.12696

  106. The relationship between cardiac autonomic function and cognitive function in Alzheimer's disease.

    Nonogaki Z, Umegaki H, Makino T, Suzuk Y, Kuzuya M.

    Geriatr Gerontol Int   Vol. 17 ( 1 ) page: 92-98   2017.1

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    DOI: 10.1111/ggi.12679

  107. 高齢者における糖尿病治療 Update

    梅垣宏行、葛谷雅文

    最新医学   Vol. 72 ( 1 ) page: 79~83   2017.1

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  108. 糖尿病とサルコペニア・フレイルの関連

    梅垣宏行

    Geriat.Med.   Vol. 55 ( 1 ) page: 41-43   2017.1

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  109. 「差分解説欄」高齢者糖尿病の血糖コントロール目標

    梅垣宏行

    日本医事新報     page: 53   2017.1

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  110. [State of glycemic control in elderly diabetic patients].

    Hattori K, Umegaki H, Komiya H, Watanabe K, Kuzuya M

    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics   Vol. 54 ( 4 ) page: 531-536   2017

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    DOI: 10.3143/geriatrics.54.531

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  111. Neuropsychological differences in Alzheimer's disease patients with or without type 2 diabetes mellitus.

    Yanagawa M, Umegaki H, Makino T, Nakashima H, Kuzuya M.

    Geriatr Gerontol Int   Vol. 16 ( 11 ) page: 1232-1235   2016.11

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    DOI: 10.1111/ggi.12703

  112. 糖尿病患者におけるフレイル・認知症

    梅垣宏行

    Medical Practice   Vol. 33 ( 8 ) page: 1245-1248   2016.8

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  113. Low intakes of carotene, vitamin B2, pantothenate, and calcium predict cognitive decline among elderly patients with diabetes mellitus: the Japanese Elderly Diabetes Intervention Trial Research Group.

    Araki A, Yoshimura Y, Sakurai T, Umegaki H, Kamada C, Iimuro S, Ohashi Y, Ito H; Japanese Elderly Diabetes Intervention Trial Research Group.

    Geriatr Gerrontol Int     2016.7

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    DOI: 10.1111/ggi.12843.

  114. Neuroanatomical correlates of error types on the Clock Drawing Test in Alzheimer's disease patients.

    Nakashima H, Umegaki H, Makino T, Kato K, Abe S, Suzuki Y, Kuzuya M.

    Geriatr Gerontol Int   Vol. 16 ( 7 ) page: 777-784   2016.7

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    DOI: 10.1111/ggi.12550

  115. 【超高齢社会における適正薬物療法の特質~ガイドラインの今日的役割と薬剤師の責務~】 高齢者糖尿病の薬物療法

    梅垣宏行

    医療ジャーナル   Vol. 52 ( 6 ) page: 1455-1458   2016.6

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  116. Therapeutic Potential of Antidiabetic Medications in the Treatment of Cognitive Dysfunction and Dementia.

    Umegaki H.

    Drugs Aging.   Vol. 33 ( 6 ) page: 399-409   2016.6

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    DOI: 10.1007/s40266-016-0375-0

  117. Endotoxemia-induced cytokine-mediated responses of hippocampal astrocytes transmitted by cells of the brain-immune interface.

    Hasegawa-Ishii S, Inaba M, Umegaki H, Unnno K, Wakabayashi K, Shimada A.

    Sci Rep.     2016.5

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    DOI: 10.1038/srep25457

  118. 認知症の栄養と食事療法.

    梅垣宏行

    Geriatric Medicine (老年医学)   Vol. 54 ( 5 ) page: 225-228   2016.5

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  119. 新時代の臨床糖尿病学(下)―より良い血糖管理をめざして―XIV.ライフステージ別糖尿病3.高齢者糖尿病(4)高齢者糖尿病の検査・診断.

    梅垣宏行

    日本臨床   Vol. 74 ( 増刊 2 ) page: 547   2016.4

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  120. 疾病予防・重症化予防栄養・運動による認知症の発症・重症化予防

    梅垣宏行

    臨床栄養 別冊セレクト11  健康寿命延伸をめざす栄養戦略     page: 94-98   2016.4

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  121. 認知症を合併した糖尿病の治療 糖尿病治療の現在と未来.

    梅垣宏行

    診断と治療   Vol. 104 ( 増刊 ) page: 198-202   2016.3

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  122. Sarcopeina and frailty in older patients with diabetes mellitus.

    Umegaki H

        2016.3

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    DOI: 10.1111/ggi.12688.

  123. Endotoxemia-induced cytokine-mediated responses of hippocampal astrocytes transmitted by cells of the brain-immune interface.

    Hasegawa-Ishii S, Inaba M, Umegaki H, Unno K, Wakabayashi K, Shimada A

    Scientific Reports   Vol. 5 ( 6 ) page: 25457   2016.3

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    DOI: 10.1038/srep25457.

  124. 精神・神経系の病気とくすり 中枢系疾患 認知症(解説/特集)

    梅垣宏行、渡邉雄貴、山田清文

    薬局    Vol. 67 ( 4 ) page: 624-632   2016.3

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  125. Factors associated with changes in brain atrophy during a 3-year observation in elderly diabetic patients; Effect of renal impairment on hippocampal atrophy.

    Kawamura T, Umemura T, Umegaki H, Imamine R, Kawano N, Mase H, Mizoguchi A, Minatoguchi M, Kusama M, Kouchi Y, Watarai A, Kanai A, Nakashima E, Hotta N.

    Dement Geriatr Cogn Disord Extra   Vol. 6 ( 1 ) page: 55-67   2016.2

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  126. 認知症患者の生命予後

    梅垣宏行、葛谷雅文

    日本老年精神医学会誌   Vol. 27 ( 2 ) page: 146-151   2016.2

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  127. Development and validation of a new quality of life scale for patients receiving home-based medical care: The Observational Study of Nagoya Elderly with Home Medical Care.

    Kamitani H, Umegaki H, Okamoto K, Kanda S, Asai A, Maeda K, Nomura H, Shimojima T, Suzuki Y, Ohshima H, Kuzuya M

    Geriatr Gerontol Int.     2016.1

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    DOI: 10.1111/ggi.12735

  128. 在宅医療における入院などに関連する因子の検討

    梅垣宏行

    日本老年医学会雑誌   Vol. 53 ( 1 ) page: 32-37   2016.1

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  129. 特集 患者さんと医療者の不安を解決 認知症なんでもQ&A ・認知症を予防するために何をすればよいですか。・認知症になったらもう治療法はないのですか。

    梅垣宏行

    糖尿病ケア   Vol. 13 ( 1 ) page: 25-28   2016.1

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  130. Risk factors for the discontinuation of home medical care among low-functioning older patients

    Umegaki H, Asai A, Kanda S, Maeda K, Shimojima T, Nomura H, Kuzuya M.

    The Journal of Nutrition, Health and Aging, First online   Vol. 20 ( 4 ) page: 453-457   2016

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  131. 認知症患者の生命予後.

    梅垣宏行、葛谷雅文

    日本老年精神医学会誌     page: 146-151   2016

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  132. Effects of Mild Cognitive Impairment on the Development of Fear of Falling in Older Adults: A Prospective Cohort Study.

    Uemura K, Shimada H, Makizako H, Doi T, Tsutsumimoto K, Lee S, Umegaki H, Kuzuya M, Suzuki T

    J Am Med Dir Assoc     2015.12

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    DOI: 10.1016/j.jamda.2015.09.014

  133. Randomized double-blind placebo-controlled multicenter trial of Yokukansan for neuropsychiatric symptoms in Alzheimer's disease.

    Furukawa K, Tomita N, Uematsu D, Okahara K, Shimada H, Ikeda M, Matsui T, Kozaki K, Fujii M, Ogawa T, Umegaki H, Urakami K, Nomura H, Kobayashi N, Nakanishi A, Washimi Y, Yonezawa H, Takahashi S, Kubota M, Wakutani Y, Ito D, Sasaki T, Matsubara E, Une K, Ishiki A, Yahagi Y, Shoji M, Sato H, Terayama Y, Kuzuya M, Araki N, Kodama M, Yamaguchi T, Arai H.

    Geriatr Gerontol Int.     2015.12

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    DOI: 10.1111/ggi.12696.

  134. The relationship between cardiac autonomic function and cognitive function in Alzheimer’s disease

    Nonogaki Z, Umegaki H, Makino T, Suzuk Yi, Kuzuya M

        2015.12

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    DOI: 10.1111/ggi.12679.

  135. Sarcopenia and diabetes: Hyperglycemia is a risk factor for age-associated muscle mass and functional reduction.

    Umegaki H

    J Diabetes Investig   Vol. 6 ( 6 ) page: 623-4   2015.11

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    DOI: 10.1111/jdi.12365

  136. 糖尿病患者の神経心理学的異常

    梅垣宏行

    Progress in Medicine   Vol. 35 ( 9 ) page: 57-62   2015.9

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  137. The prevalence of homebound individuals in the elderly population: a survey in a city area in Japan Reviewed

    Umegaki H, Yanagawa M, Nakashima H, Makino T, Kuzuya M.

    Nagoya Journal of Medical Science   Vol. 77 ( 3 ) page: 439-446   2015.8

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  138. Effects of leisure activities at home on perceived care burden and the endocrine system of caregivers of dementia patients: a randomized controlled study.

    Hirano A, Umegaki H, Suzuki Y, Hayashi T, Kuzuya M

    Int Psychogeriatr   Vol. 20   page: 1-8   2015.8

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  139. Neuroanatomical correlates of error types on the Clock Drawing Test in Alzheimer's disease patients. Reviewed

    Nakashima H, Umegaki H, Makino T, Kato K, Abe S, Suzuki Y, Kuzuya M.

    Geriatr Gerontol Int     2015.7

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    DOI: 10.1111/ggi.12550

  140. ロコモティブシンドロームのすべて 認知症とロコモ

    梅垣宏行

    医師会雑誌   Vol. 144 ( 特別号(1) ) page: 289-291   2015.6

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  141. 高齢者糖尿病の食事・運動療法の進歩

    梅垣宏行

    Geriatric Medicine(老年医学)   Vol. 53 ( 5 ) page: 457-460   2015.6

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  142. 高齢者糖尿病の食事・運動療法の進歩.

    梅垣宏行

    Geriatric Medicine(老年医学)   Vol. 53 ( 5 ) page: 457-460   2015.6

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  143. Q2 メモリークリニックとは?Q4 認知症の診断過程と鑑別は?

    梅垣宏行

    Medical Rehabilitation (2015年5月増刊号)   Vol. 183 ( 増刊 ) page: 7-10,16-19   2015.5

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  144. Association of decrease in carbohydrate intake with reduction in abdominal fat during 3-month moderate low-carbohydrate diet among non-obese Japanese patients with type 2 diabetes.

    Sasakabe T, Haimoto H, Umegaki H, Wakai K.

    Geriatr Gerontol Int   Vol. 64 ( 5 ) page: 618-25   2015.5

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  145. Dementia: Type 2 diabetes has a slow and insidious effect on cognition. Reviewed

    Umegaki H.

    Nat Rev Neurol.   Vol. 11 ( 3 ) page: 127-8   2015.3

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  146. Association of decrease in carbohydrate intake with reduction in abdominal fat during 3-month moderate low-carbohydrate diet among non-obese Japanese patients with type 2 diabetes.

    Sasakabe T,Haimoto H, Umegaki H, Wakai K.

    Metabolism.   Vol. 64 ( 5 ) page: 618-25   2015.3

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  147. 特集 在宅医療の新しい展開/在宅医療におけるQOL評価

    梅垣宏行

    Geriatric Msdicine   Vol. 53 ( 2 ) page: 139-142   2015.2

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  148. Increased recruitment of bone marrow-derived cells into the brain associated with altered brain cytokine profile in senescence-accelerated mice. Reviewed

    Hasegawa-Ishii S, Inaba M, Li M, Shi M, Umegaki H, Ikehara S, Shimada A.

    Brain Struct Funct.     2015.1

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    DOI: 10.1007/s00429-014-0987-2

  149. 高齢者糖尿病におけるセルフケアの援助

    梅垣宏行

    プラクティス   Vol. 32 ( 1 ) page: 53-57   2015.1

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  150. 治し支える医療としての在宅医療の現状と展望 在宅医療におけるQOL評価について

    梅垣宏行

    月刊「カレントテラピー」     page: Vol.33 No.2   2015

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  151. 高齢者糖尿病患者に対するレパグリニドの安全性・有効性の検討

    梅垣宏行

    Diabetes Frontier   Vol. 26 ( 1 ) page: 1   2015

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  152. Factors Associated with Brain Atrophy Estimated with Automatic Voxel-Based Morphometry of Structural Magnetic Resonance Images in Elderly Diabetic Patients: Impact of Albuminuria on Hippocampal Atrophy. Reviewed

    Takahiko Kawamura, Toshitaka Umemura, Rui Imamine, Hiroyuki Umegaki, Naoko Kawano, Asako Mizoguchi, Mariko Kawai,Makiko Minatoguchi, Minoru Kusama, Yu Kouchi, Atsuko Watarai, Akio Kanai, Eitaro Nakashima and Nigishi Hotta

    J Diabetes Metab     2014.12

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    DOI: 10.4172/2155-6156.1000491

  153. 高齢者糖尿病と認知症

    梅垣宏行

    月間糖尿病   Vol. 6 ( 11 ) page: 43-48   2014.12

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  154. Relationship between Small Cerebral White Matter Lesions and Cognitive Function in Patients with Alzheimer's Disease and Amnestic Mild Cognitive Impairment Reviewed

    MakinoT, Umegaki H, Suzuki Y, Yanagawa M, Nonogaki Z, Nakashima H, Kuzuya M.

    Gerontol Geriatr Int   Vol. 14 ( 4 ) page: 819-26   2014.10

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    DOI: 10.1111/ggi.12176

  155. 特集/認知症の原因・予防から診断・治療まで  1.認知症の治療―認知症患者の行動・心理症状への対応

    梅垣宏行 葛谷雅文

    月刊「臨床と研究」   Vol. 91 ( 7 ) page: 919-923   2014.7

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  156. 認知症と糖尿病治療における課題と展望(座談会)

    朝田隆、古川勝敏、梅垣宏行、田中志子、荒木厚

      Vol. 52 ( 7 ) page: 803-811   2014.7

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  157. アルツハイマー型認知症患者の近時記憶障害に対するリバスチグミンの効果の検討.

    梅垣宏行

    新薬と臨牀   Vol. 63 ( 7 ) page: 1168-1171   2014.7

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  158. 特集:神経疾患治療薬の剤形と使い分け 8.アルツハイマー型認知症治療薬の剤形

    梅垣宏行

    学術季刊誌BRAIN MEDICAL   Vol. 26 ( 2 ) page: 8.アルツハイマー型認知症治療薬の剤形   2014.6

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  159. 全人的医療を目指す 認知症と転倒

    梅垣宏行

    クリニシアン   Vol. 61 ( 4-5 ) page: 487-494   2014.5

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  160. Factors associated with cognitive decline in older subjects with type 2 diabetes mellitus during a 6-year observation

    Umegaki H, Kawamura T, Umemura T, Kawano N

    Geriatr Gerontol Int     2014.3

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    DOI: 10.1111/ggi.12273

  161. 認知症の身体合併症へのアプローチ:摂食障害

    梅垣宏行

    老年精神医学雑誌   Vol. 25 ( 増刊 ) page: 98-102   2014.3

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  162. Effect of renal impairment on cognitive function during a 3-year follow-up in elderly patients with type 2 diabetes: association with microinflammation

    Journal of Diabetes Investigation   Vol. 5 ( 5 ) page: 597-605   2014.2

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  163. Burden reduction of caregivers for users of care services provided by the public long-term care insurance system in Japan Reviewed

    Umegaki H, Yanagawa M, Nonogaki Z, Nakashima H, Kuzuya M, Endo H

    Archives of Gerontology and Geriatrics   Vol. 58 ( 1 ) page: 130-133   2014

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  164. Three-graded stratification of carbohydrate restriction by level of baseline hemoglobin A1c for type 2 diabetes patients with a moderate low-carbohydrate diet

    Haimoto H, Sasakabe T, Kawamura T, Umegaki H, Komeda M, Wakai K

    Nutrition & Metabolism   Vol. 28 ( 11 ) page: 33   2014

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  165. Type 2 diabetes as a risk factor for cognitive impairment : current insights

    Umegaki H

    Clinical Interventions in Aging   Vol. 28 ( 9 ) page: 1011-1019   2014

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  166. Impaired glycemia and Alzheimer's disease

    Umegaki H

    Neurobiology of Aging   Vol. 35 ( 10 ) page: e21   2014

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  167. Dynamics of bone marrow-derived cells relevant to the brain-immune cell-cell interactions under non-inflammatory conditions

    Hasegawa-Ishii S, Inaba M, Ming Li, Umegaki H, Ikehara S, Shimada A.

    Curr Trends Neurol   Vol. 8   page: 39-52   2014

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  168. 認知症の発症予防因子としての栄養

    梅垣宏行

      Vol. 51 ( 4 ) page: 413-417   2013.10

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  169. 糖尿病と認知症

    梅垣宏行

    認知症の最新医療   Vol. 3 ( 4 ) page: 170-174   2013.10

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  170. 高齢者糖尿病における生活指導のあり方

    梅垣宏行

    月刊糖尿病   Vol. 5 ( 4 ) page: 20-27   2013.4

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  171. Insulin resistance in the brain: a new therapeutic target for Alzheimer's disease Reviewed

    Umegaki H

    J Diabetes Investig   Vol. 4 ( 2 ) page: 150-1   2013.3

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  172. Cognitive dysfunction: an emerging concept of a new diabetic complication in the elderly Reviewed

    Umegaki H, Hayashi T, Nomura H, Yanagawa M, Nonogaki Z, Nakshima H, Kuzuya M

    Geriatr Gerontol Int   Vol. 13 ( 1 ) page: 28-34   2013

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  173. Cognitive impairments and functional declines in older adults at high risk for care needs Reviewed

    Umegaki H, Suzuki Y, Yanagawa M, Nonogaki Z, Nakashima H, Kuzuya M, Endo H

    Geriatr Gerontol Int   Vol. 13 ( 1 ) page: 77-82   2013

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  174. Care for Alzheimer's disease Reviewed

    Umegaki H, Takechi H, Dodge H

    J Alzheimers Dis     2013

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    DOI: 10.1155/2013/516852

  175. Dementia and diabetes: Towards the prevention of dementia through glycemic control. Reviewed

    Umegaki H

    Journal of Gerontology Geriatrics Research     page: 00-00   2013

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  176. The response of the autonomic nervous system to the cholinesterase inhibitor, donepezil Reviewed

    Umegaki H , Oyun Khookhor,

    Neuroendocrinology Letters   Vol. 34 ( 5 ) page: 383-387   2013

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  177. Association of Chronic Kidney Disease and Cerebral Small Vessel Disease with Cognitive Reviewed

    Umemura T, Kawamura T, Umegaki H, Kawano N,Mashita S, Sakakibara T, Hotta N, Sobue G.

    Dement Geriatr Cogn Disord Extra   Vol. 3   page: 212-222   2013

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  178. The cholinergic stimulation of the hippocampus induced the activation of the sympathetic nervous system. Reviewed

    Oyun Khookhor, Umegaki H

    Neuroendocrinology Letters   Vol. 34 ( 1 ) page: 58-61   2013

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  179. 第54回日本老年医学会学術集会記録 <シンポジウム8:高齢者糖尿病の管理―J-EDITから得られたもの―>5.認知症のリスクと対応

    梅垣宏行

    日本老年医学会雑誌   Vol. 50 ( 1 ) page: 65-67   2013

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  180. Dietary pattern and mortality in Japanese elderly patients with type 2 diabetes mellitus - Does vegetable- and fish-rich diet improve mortality ?: An explanatory study Reviewed

    Iimuro S, Yoshimura Y, Umegaki H, Sakurai T, Araki A, Ohashi Y, Ito H

    Geriatr Gerontol Int   Vol. 12 ( suppl 1 ) page: 59-67   2012

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  181. Lower Physical Activity, but not Excessive Calorie Intake, is Associated with Metabolic Syndrome in Elderly with Type 2 Diabetes Mellitus: Japanese Elderly Diabetes Intervention Trial (J-EDIT) Reviewed

    Iijima K, Iimuro S, Ohashi Y, Sakurai T, Umegaki H, Araki A, Yoshimura Y, Ouchi Y, Ito H

    Geriatr Gerontol Int   Vol. 12 ( suppl 1 ) page: 68-76   2012

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  182. Lower Physical Activity is a Strong Predictor of Cardiovascular Events in Elderly Patients with Type 2 Diabetes Mellitus beyond Traditional Risk Factors: Japanese Elderly Diabetes Intervention Trial (J-EDIT) Reviewed

    Iijima K, Iimuro S, Shionzaki T,Ohashi Y, Sakurai T, Umegaki H, Araki A, Ouchi Y, Ito H

    Geriatr Gerontol Int   Vol. 12 ( suppl 1 ) page: 77-87   2012

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  183. Effective prevention of cardiovascular disease and diabetes-related events with atorvastatin in Japanese elderly patients with type 2 diabetes mellitus: adjusting for treatment changes using a marginal structural proportional hazards model and a rank-preserving structural failure time model Reviewed

    Shinozaki T, Matsuyama Y, Iimuro S, Umegaki H, Sakurai T, Araki A, Ohashi Y, Ito H

    Geriatr Gerontol Int   Vol. 12 ( suppl 1 ) page: 88-102   2012

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  184. Risk factors associated with cognitive decline in the elderly with type 2 diabetes; Baseline data analysis of Japanese elderly diabetes intervention trial (J-EDIT) Reviewed

    Umegaki H, Iimuro S, Shinozaki T, Araki A, Sakurai T, Iijima K, Ohashi Y, Ito H

    Geriatr Gerontol Int   Vol. 12 ( suppl 1 ) page: 103-109   2012

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  185. Risk factors associated with cognitive decline in the elderly with type 2 diabetes:Pooled logistic analysis of a 6-year observation in the Japanese elderly diabetes intervention trial (J-EDIT) Reviewed

    Umegaki H, Iimuro S,Shinozaki T, Araki A, Sakurai T, Iijima K, Ohashi Y, Ito H

    Geriatr Gerontol Int   Vol. 12 ( suppl 1 ) page: 110-116   2012

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  186. Risk factors for a 6-year decline in physical disability and functional limitations among elderly people with type 2 diabetes (J-EDIT) Reviewed

    Sakurai T, Iimuro S, Umegaki H, Araki A, Ohashi Y, Ito H

    Geriatr Gerontol Int   Vol. 12 ( suppl 1 ) page: 117-126   2012

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  187. Factors associated with progression of diabetic nephropathy in Japanese elderly patients with type 2 diabetes: Sub-analysis of the Japanese Elderly Diabetes Intervention Trial Reviewed

    Araki S,Nishio Y, Araki A, Umegaki H, Sakurai T, Iimuro S, Ohashi Y, Uzu T, Maegawa H, Kashiwagi A, Ito H

    Geriatr Gerontol Int   Vol. 12 ( suppl 1 ) page: 127-133   2012

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  188. The effects of mild cognitive impairment on driving performance in older drivers Reviewed

    Kawano N, Iwamoto K, Ebe K, Suzuki Y, Hasegawa J, Ukai K, Umegaki H, Iidaka T, Ozaki N

    J Am Geriatr Soc   Vol. 60 ( 7 ) page: 1379-1381   2012

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  189. Immunohistochemical demonstration of increased prostaglandin F2alpha levels in the rat hippocampus following kainic acid-induced seizures Reviewed

    Takei S, Hasegawa-Ishii S, Uekawa A, Chiba Y, Umegaki H, Hosokawa M, David F Woodward, Watanabe K, Shimada AM

    Neuroscience   Vol. 218   page: 295-304   2012

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  190. Reduction in urinary albumin excretion with a moderate low-carbohydrate diet in patients with type 2 diabetes: A 12-month intervention Reviewed

    Haimoto H, Sasakabe T, Umegaki H, Wakai K

    Diabetes Metab Syndr Obes   Vol. 5   page: 283-291   2012

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  191. Pharmacist-based Donepezil Outpatient Consultation Service to improve medication persistence Reviewed

    Watanabe N, Yamamura K, Suzuki Y, Umegaki H, Shigeno K, Matsushita R, Sai Y, Miyamoto K, Yamada K

    Patient Prefer Adherence   Vol. 6   page: 605-611   2012

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  192. Slower adaptation to driving simulator and simulator sickness in older adults Reviewed

    Kawano N, Iwamoto K, Ebe K, Aleksic B, Noda A, Umegaki H, Kuzuya M, Iidaka T, Ozaki N

    Aging Clin Exp Res   Vol. 24   page: 285-289   2012

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  193. Effects of total and green vegetable intakes on glycated hemoglobin A1c and triglycerides in elderly patients with type 2 diabetes mellitus: the Japanese Elderly Intervention Trial Reviewed

    Takahashi K, Kamada C, Yoshimura H, Okumura R, Iimuro S, Ohashi Y, Araki A, Umegaki H, Sakurai T, Yoshimura Y, Ito H

    Geriatr Gerontol Int   Vol. 12 ( suppl 1 ) page: 50-58   2012

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  194. Falls in elderly at high risk of requiring care Reviewed

    Umegaki H, Suzuki Y, Yanagawa M, Nonogaki Z, Endo H

    Geriatr Gerontol Int   Vol. 12 ( suppl 1 ) page: 147-148   2012

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  195. Dysphagia in older adults at high risk of requiring care Reviewed

    Umegaki H, Suzuki Y, Yanagawa M, Nonogaki Z, Nakashima H, Endo H

    Geriatr Gerontol Int   Vol. 12 ( 2 ) page: 359-361   2012

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  196. Neurodegeneration in diabetes mellitus Reviewed

    Umegaki H

    Adv Exp Med Biol   Vol. 724   page: 258-265   2012

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  197. Long-term multiple risk factor interventions in Japanese elderly diabetic patients: the Japanese Elderly Diabetes Intervention Trial--study design, baseline characteristics and effects of intervention Reviewed

    Araki A, Iimuro S, Sakurai T, Umegaki H, Iijima K, Nakano H, Oba K, Yokono K, Sone H, Yamada N, Ako J, Kozaki K, Miura H, Kashiwagi A, Kikkawa R, Yoshimura Y, Nakano T, Ohashi Y, Ito H

    Geriatr Gerontol Int   Vol. 12 ( suppl 1 ) page: 7-17   2012

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  198. Non-high-density lipoprotein cholesterol: an important predictor of stroke and diabetes-related mortality in Japanese elderly diabetic patients Reviewed

    Araki A, Iimuro S, Sakurai T, Umegaki H, Iijima K, Nakano H, Oba K, Yokono K, Sone H, Yamada N, Ako J, Kozaki K, Miura H, Kashiwagi A, Kikkawa R, Yoshimura Y, Nakano T, Ohashi Y, Ito H

    Geriatr Gerontol Int   Vol. 12 ( suppl 1 ) page: 18-28   2012

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  199. Relations of nutritional intake to age, gender and BMI in Japanese elderly patients with type 2 diabetes - Japanese Elderly Diabetes Intervention Trial(J-EDIT) Reviewed

    Yoshimura Y, Kamada C,Keiko Takahashi, Kaimoto T, Iimuro S, Ohashi Y,Araki A,Umegaki H, Sakurai T, Ito H

    Geriatr Gerontol Int   Vol. 12 ( suppl 1 ) page: 29-40   2012

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  200. Optimal energy distribution of carbohydrate intake for Japanese elderly patients with type 2 diabetes: the Japanese Elderly Intervention Trial Reviewed

    Kamada C, Yoshimura H, Okumura R, Takahashi K, Iimuro S, Ohashi Y, Araki A, Umegaki H, Sakurai T, Yoshimura Y, Ito H

    Geriatr Gerontol Int   Vol. 12 ( suppl 1 ) page: 41-49   2012

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  201. Neurodegeneration dysfunction in old diabetes- management and treatment Reviewed

    Umegaki H

    Adv Exp Med Biol   Vol. 771   page: 465-470   2012

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  202. Effective prevention of cardiovascular disease and diabetes-related events with atorvastatin in Japanese elderly patients with type 2 diabetesmellitus: adjusting for treatment changes using a marginal structural proportional hazards model and a rank-preserving structual failure time model Reviewed

    Shinozaki T, Matsuyama Y, Iimuro S, Umegaki H, Sakurai T, Araki A, Ohashi Y, Ito H

    Gerontol Geriatr Int   Vol. 12 ( suppl 1 ) page: 88-102   2012

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  203. 特集:高齢者の運転をめぐって 4.もの忘れ外来における運転指導

    梅垣宏行

      Vol. 50 ( 2 ) page: 155-158   2012

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  204. 特集:糖尿病患者における認知症―基礎と臨床の最新知見―Ⅲ.検査 ①糖尿病患者の神経心理学的異常

    梅垣宏行

    月刊糖尿病   Vol. 4 ( 9 ) page: 57-64   2012

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  205. 特集:アルツハイマー型認知症治療薬 ドネペジル塩酸塩が構築してきた治療エビデンス

    梅垣宏行

    薬局   Vol. 63 ( 2 ) page: 241-244   2012

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  206. Defects in cytokine-mediated neuroprotective glial responses to excitotoxic hippocampal injury in senescence-accelerated mouse Reviewed

    Hasegawa-Ishii S, Takei S, Inaba M, Umegaki H, Chiba Y, Furukawa A, Kawamura N, Hosokawa M, Shimada A.

    Brain Behav Immun   Vol. 25 ( 1 ) page: 83-100   2011

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  207. Association between the caregiver's burden and physical activity in community-dwelling caregivers of dementia patients Reviewed

    Hirano A, Suzuki Y, Kuzuya M, Onishi J, Hasegawa J, Ban N, Umegaki H

    Arch Gerontol Geriatr   Vol. 52 ( 3 ) page: 295-298   2011

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  208. Morphological impairments in microglia precede age-related neuronal degeneration in senescence-accelerated mice Reviewed

    Hasegawa-Ishii S, Takei S, Chiba Y, Furukawa A, Umegaki H, Iguchi A, Kawamura N, Yoshikawa K, Hosokawa M, Shimada A

    Neuropathology   Vol. 31 ( 1 ) page: 20-28   2011

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  209. Association between improvements in insulin resistance and changes in cognitive function in elderly diabetic patients with normal cognitive function Reviewed

    Yanagawa M, Umegaki H, Uno T, Oyun K, Kawano N, Maeno H, Yamanouchi K, Sato Y

    Geriatr Gerontol Int   Vol. 11 ( 3 ) page: 341-7   2011

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  210. Effect of a moderate low-carbohydrate diet on preferential abdominal fat loss and cardiovascular risk factors in patients with type 2 diabetes Reviewed

    Sasakabe T, Haimoto H, Umegaki H, Wakai K

    Diabetes Metab Syndr Obes   Vol. 4   page: 167-74   2011

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  211. Strong association of insulin resistance with urinary albumin excretion in the elderly Reviewed

    Umegaki H, Haimoto H, Isikawa J , Shibayama H, Watanabe Y

    J Am Geriatr Soc   Vol. 59 ( 7 ) page: 1361-2   2011

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  212. Factors Associated with Cognitive Declines in Elderly Diabetics Reviewed

    Umegaki H, Kawamura T, Kawano N, Umemura T, Kanai A, Sano T

    Dementia and Geriatric Cognitive Disorders Extra   Vol. 1   page: 1-9   2011

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  213. The association of lower hemoglobin level with depressive mood in elderly women at high risk of requiring care Reviewed

    Umegaki H, Yanagawa M, Endo H

    Geriatr Gerontol Int   Vol. 11 ( 3 ) page: 262-6   2011

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  214. Does cerebral small vessel disease predict future decline of cognitive function in well controlled elderly patients with type 2 diabetes? Reviewed

    Imamine R, Kawamura T, Umemura T, Umegaki H, Kawano N, Hotta M, Kouchi Y,Hatsuda S, Watarai A, Kanai A, Nakashima E, Sano T, Sakakibara T, Nakamura J, Hotta N

    Diabetes Res Clin Pract   Vol. 94   page: 91-9   2011

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  215. Endothelial and inflammatory markers in relation to progression ofischaemic cerebral small-vessel disease and cognitive impairment: a 6-year longitudinal study in patients with type 2 diabetes mellitus Reviewed

    Umemura T, Kawamura T, Umegaki H, Mashita S, Kanai R, Hotta N, Sobue G

    J Neurol Neursurg Pshichiatr   Vol. 82 ( 11 ) page: 1186-1194   2011

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  216. Part2-疾患別:高齢者の栄養ケア 認知症

    梅垣宏行

    臨床栄養   Vol. 118 ( 6 ) page: 622-626   2011

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  217. 栗田論文について(3)(レター)

    梅垣宏行

    日本老年医学会雑誌   Vol. 47 ( 3 ) page: 267   2010.5

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  218. 認知症高齢者を対象とした音楽療法に関する文献的検討 介入頻度と効果の関係

    山口理恵、河野直子、梅垣宏行

    日本認知症ケア学会誌   Vol. 9 ( 1 ) page: 89-96   2010.4

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  219. Pathophysiology of cognitive dysfunction in older people with type 2 diabetes: vascular changes or neurodegeneration? Reviewed

    Age Ageing.   Vol. 39 ( 1 ) page: 8-10   2010

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  220. Effects of educational background on verbal fluency task performance in older adults with Alzheimer's disease and mild cognitive impairment Reviewed

    Kawano N, Umegaki H, Suzuki Y, Yamamoto S, Mogi N, Iguchi A.

    Int Psychogeriatr   Vol. 22 ( 6 ) page: 995-1002   2010

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  221. Influence of regular exercise on subjective sense of burden and physical symptoms in community-dwelling caregivers of dementia patients: A randomized controlled trial Reviewed

    Hirano A, Suzuki Y, Kuzuya M, Onishi J, Ban N, Umegaki H

    Arch Gerontol Geriatr   Vol. 53 ( 2 ) page: e158-63   2010

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  222. Age-associated increase in abdominal obesity and insulin resistance, and usefulness of AHA/NHLBI definition of metabolic syndrome for predicting cardiovascular disease in Japanese elderly with type 2 diabetes mellitus Reviewed

    Sakurai T, Iimuro S, Araki A, Umegaki H, Ohashi Y, Yokono K, Ito H

    Gerontology   Vol. 56 ( 2 ) page: 141-9   2010

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  223. 認知症高齢者を対象とした音楽療法に関する文献的検討 介入頻度と効果の関係

    山口理恵、河野直子、梅垣宏行

    認知症ケア学会誌   Vol. 9 ( 1 ) page: 89-95   2010

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  224. (座談会)期待される高齢者医療

    梅垣宏行、細井孝之、浅井俊亘、牧 靖典、高橋 昇

    現代医学   Vol. 58 ( 2 ) page: 297-324   2010

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  225. 糖尿病における認知機能障害 Cognitive dysfunction in diabetic patients

    梅垣宏行

    老年期認知症研究会誌   Vol. 16   page: 99-100   2010

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  226. 認知症治療薬に関する薬剤師の取り組みの今後

    梅垣宏行

    医薬ジャーナル   Vol. 46 ( 5 ) page: 108-110   2010

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  227. 軽度認知症をスクリーニングするための神経心理学的テスト・バッテリー

    河野直子、梅垣宏行

    老年精神医学雑誌   Vol. 21 ( 2 ) page: 209-214   2010

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  228. Changes in the perception of dementia in Japan Reviewed

    Umegaki H, Suzuki Y, Ohnishi J, Iguchi A

    Int Psychogeriatr.   Vol. 21 ( 4 ) page: 793-7   2009

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  229. Responses of hypothalamo-pituitary-adrenal axis to a cholinesterase inhibitor Reviewed

    Umegaki H, Yamamoto A, Suzuki Y, Iguchi A

    Neuroreport   Vol. 20 ( 15 ) page: 1366-70   2009

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  230. Low HDL-cholesterol is associated with the risk of stroke in elderly diabetic individuals: Changes in the risk for atherosclerotic diseases at various ages Reviewed

    Hayashi T, Kawashima S, Itoh H, Yamada N, Sone H, Watanabe H, Hattori Y, Ohrui T, Yokote K, Nomura H, Umegaki H, Iguchi A; on behalf of Japan CDM group

    Diabetes Care   Vol. 32 ( 7 ) page: 1221-3   2009

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  231. Effects of a low-carbohydrate diet on glycemic control in outpatients with severe type 2 diabetes Reviewed

    Haimoto H, Sasakabe T, Wakai K, Umegaki H

    Nutr Metab (Lond)   Vol. 6   page: 21   2009

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  232. Association of higher carbohydrate intake with depressive mood in elderly diabetic women Reviewed

    Umegaki H, Iimuro S, Araki A, Sakurai T, Iguchi A, Ohashi Y, Ito H

    Nurtritional Neuroscience   Vol. 12 ( 6 ) page: 267-71   2009

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  233. Different contribution of the lateral bed nucleus of the stria terminalis in intrahippocampal neostigmine-induced elevation of plasma glucoseand adrenocorticotropic hormone in free moving rats Reviewed

    Zhu W, Cui J, Zhang R, Umegaki H

    Neuroendocrinology Letter   Vol. 30 ( 4 ) page: 511-4   2009

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  234. Acute metabolic responses to a high-carbohydrate meal in outpatients with type 2 diabetes treated with a low-carbohydrate diet: a crossover meal tolerance study Reviewed

    Haimoto H, Sasakabe T, Umegaki H, Wakai K

    Nutr Metab (Lond)   Vol. 6 ( 1 ) page: 52   2009

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  235. MMSE24点以上の高齢者群における神経心理学的検査を用いた認知症の探索

    河野直子、鈴木裕介、山本さやか、井口昭久、梅垣宏行

    Dementia Japan   Vol. 22 ( 3 ) page: 298-307   2009

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  236. Factors Associated with Lower Mini Mental State Examination Scores in Elderly Japanese Diabetes Mellitus Patients Reviewed

    Umegaki H Satoshi Iimuro, Si Kaneko T, Araki A, Sakurai T Ohashi Y, Akihisa Iguchi A, Ito H

    Neurobiol Aging   Vol. 29 ( 7 ) page: 1022-6   2008

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  237. Visceral fat contribution of insulin resistance in elderly people Reviewed

    Umegaki H, Haimoto H, Ishikawa J, Kario K.

    J Am Geriatr Soc   Vol. 56 ( 7 ) page: 1373-1375   2008

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  238. Aging of the striatum: mechanisms and interventions Invited Reviewed

    Umegaki H, Roth GS, Ingram DK.

    Age   Vol. 30 ( 4 ) page: 251-261   2008

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  239. D2R DNA transfer into the nucleus accumbens attenuates cocaine self-administration in rats Reviewed

    Thanos PK, Michaelides M, Umegaki H, Volkow ND

    Synapse   Vol. 62 ( 7 ) page: 481-6   2008

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  240. Long-term effects of a loose restriction of carbohydrates diet on HbA1c levels, BMI and tapering of sulfonylureas in type 2 diabetes: a two-year follow-up study Reviewed

    Haimoto H, Iwata M, Wakai K, Umegaki H

    Diab Res Clin Prac   Vol. 79 ( 2 ) page: 350-6   2008

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  241. Importance of Lipid Levels in Elderly Diabetic Individuals. Reviewed

    Hayashi T, Kawashima S, Itoh H, Yamada N, Sone H, Watanabe H, Hattori Y, Ohrui T, Yoshizumi M, Yokote K, Kubota K, Nomura H, Umegaki H, Iguchi A; on behalf of Japan CDM group

    Circ J   Vol. 72 ( 2 ) page: 218-25   2008

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  242. Effect of the entorhinal cortex on diurnal ACTH and corticosterone release in rats Reviewed

    Zhu W, Zhang R, Changchun H, Umegaki H

    Neuroendocrinol lett   Vol. 29 ( 1 ) page: 159-62   2008

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  243. Discontinuation of Donepezil for the Treatment of Alzheimer's Disease in Geriatric Practice Reviewed

    Umegaki H, Itoh A, Suzuki Y, Nabeshima T

    Int. Psychogeriatr.   Vol. 20 ( 4 ) page: 800-6   2008

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  244. Cognitive Dysfunction in Diabetic Elderly Reviewed

    Umegaki H, Kawamura T, Mogi N, Umemura T, Kanai A, Sano T

    Age Ageing   Vol. 37 ( 4 ) page: 458-61   2008

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  245. 高齢者のメタボリックシンドローム (Invited Review)

    梅垣宏行

    日老医誌   Vol. 45 ( 3 ) page: 330-334   2008

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  246. Attitudes toward disclosing the diagnosis of dementia in Japan Reviewed

    Umegaki H, Onishi J, Suzuki Y, Endo H, Iguchi A

    Int. Psychogeriatr   Vol. 19 ( 2 ) page: 253-265   2007

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  247. Clinical profiles of autopsy-confirmed dementia with Lewy bodies at institutionalization: Comparison with Alzheimer's disease Reviewed

    Fujishiro H, Umegaki H, Suzuki Y, Isojima D, Akatsu H, Ikari H, Iguchi A, Kosaka K

    Psychogeriatrics   Vol. 7 ( 3 ) page: 98-103   2007

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  248. Which two questions of Mini-Mental State Examination (MMSE) should we start from? Reviewed

    Onishi J, Suzuki Y, Umegaki H, Kawamura T, Imaizumi M, Iguchi A

    Arch Gerontol Geriatr   Vol. 44 ( 1 ) page: 43-8   2007

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  249. 認知症診療に対する態度に関する医師会会員へのアンケート調査-地域における認知症の診療体制の確立のために-

    梅垣宏行、鈴木裕介、葛谷雅文、井口昭久

    日老医誌   Vol. 44   page: 102-106   2007

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  250. 老年科における外来認知症診療の現状と展望:名古屋大学医学部附属病院老年科「外来もの忘れ検査」の利用統計から

    河野直子、梅垣宏行、茂木七香、山本さやか、鈴木裕介、井口昭久

    日老医誌   Vol. 44   page: 611-618   2007

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  251. ADAS単語カードを用いた遅延再生課題の軽度認知機能低下識別に対する有用性:外来もの忘れ検査利用者を対象とした検討

    河野直子、梅垣宏行、鈴木裕介、山本さやか、茂木七香、井口昭久

    日老医誌   Vol. 44 ( 4 ) page: 490-496   2007

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  252. Functional Recovery of the Striatal Cholinergic System in Aged Rats by Adenoviral Vector-mediated Gene Transfer of Dopamine D2 Receptor Reviewed

    Umegaki H, Yamaguchi Y, Ishiwata, K, Roth GS, Ingram DK, Iguchi A

      Vol. 127 ( 10 ) page: 813-815   2006

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  253. Behavioral, Psychological, and Physical Symptoms in Group Homes for the Older Adults with Dementia Reviewed

    Onishi J, Suzuki Y, Umegaki H, Endo H, Kawamura T, Imaizumi M, Iguchi A

    Int Psychogeriatr   Vol. 3   page: 1-12   2006

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  254. Association between insulin resistance and cognitive function in elderly diabetic patients Reviewed

    Suzuki M, Umegaki H, Uno T, Oyun, O, Mogi N, Maeno H, Yamanouchi K, Iguchi A, Sato Y

    Geriatr. Gerotr, Intr   Vol. 6   page: 254-9   2006

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  255. Stimulation of the Hippocampal Glutamate Receptor Systems Induces Stress-like Responses Reviewed

    Umegaki H, Yamamoto A, Suzuki Y, Iguchi A

    Neuroendocrinology letters   Vol. 27 ( 3 ) page: 339-43   2006

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  256. Cognitive dysfunction associates with white matter hyperintensities and subcortical atrophy on magnetic resonance imaging of the elderly diabetes mellitus Japanese Elderly Diabetes Intervention Trial (J-EDIT) Reviewed

    Akisaki T, Sakurai T, Takata T, Umegaki H, Araki A, Mizuno S, Tanaka S, Ohashi Y, Iguchi A, Yokono K and Ito H

    Diabetes/Met Res Rev   Vol. 22 ( 5 ) page: 376-84   2006

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  257. Microdialysis measurement of acetylcholine in rat hippocampus during severe insulin-induced hypoglycemia. Reviewed

    Umegaki H, Yamaguchi Y, Suzuki Y, Iguchi A

    Neuroendocrinol lett   Vol. 27 ( 1-2 ) page: 128-32   2006

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  258. Cognitive Function in the Elderly with Diabetes Mellitus Reviewed

    Umegaki H, Iguchi A

    J Clin Biochem Neutr   Vol. 38 ( 1 ) page: 19-24   2006

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  259. Factors associated with cognitive impairment in elderly diabetes mellitus patients Reviewed

    Suzuki M, Umegaki H, Ieda S, Mogi N, Iguchi A

    J Am Geriatr Soc   Vol. 54 ( 3 ) page: 558-9   2006

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  260. A Comparison of Depressive Mood of older adults in a Community, Nursing Homes, and a Geriatric Hospital: Factor Analysis of Geriatric Depression Scale Reviewed

    Onishi J, Suzuki Y, Umegaki H, Endo H, Kawamura T, Iguchi A

    J Geriatr Psychiatry Neurol   Vol. 19 ( 1 ) page: 26-31   2006

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  261. Depletion of cholinergic neurons in nucleus of the medial septum and the vertical limb of the diagonal band in dementia with Lewy bodies. Invited Reviewed

    Fujishiro H. Umegaki H, Isojima D, Akatsu H, Iguchi A, Kosaka K

    Acta Neuropathol   Vol. 11 ( 2 ) page: 109-14   2006

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  262. 痴呆と未病

    梅垣宏行

    日老医誌   Vol. 43 ( 1 ) page: 87-88   2006

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  263. 日本人高齢糖尿病の認知症、認知機能低下の危険因子—J-EDIT登録症例を用いた検討

    梅垣宏行、櫻井孝、荒木厚、飯室聡、大橋靖雄、井藤英喜

    糖尿病合併症   Vol. 20 ( 1 ) page: 71-74   2006

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  264. Dopamine D2 receptor has a role in memory function. Implications for dopamine-acetylcholine interaction in the ventral hippocampus Reviewed

    Fujishiro H, Umegaki H, Suzuki Y, Oohara-Kurotani S, Yamaguchi Y, Iguchi A

    Psychopahrmacology   Vol. 182 ( 2 ) page: 253-61   2005

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  265. Dopamine D2R DNA transfer in dopamine D2 receptor-deficient mice: Effects on ethanol drinking Reviewed

    Thanos PK , Rivera SN, Weaver K,. Grandy DK, Rubinstein M, Umegaki H , Wang GJ , Hitzemann R ,Volkow ND

    Life Sciences   Vol. 77   page: 130-139   2005

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  266. The entorhinal cortex regulates blood glucose level in response to microinjection of neostigmine into the hippocampus Reviewed

    Adeli-Rankouhi S, Umegaki H, Zhu W, Suzuki Y, Kurotani S, Ieda S, Iguchi A

    Neuroendocrinol lett   Vol. 26   page: 225-230   2005

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  267. Influence of behavioral and psychological symptoms of dementia (BPSD) and environment of care on caregivers' burden Reviewed

    Onishi J, Suzuki Y, Umegaki H, Nakamura A, Endo H, Iguchi A

    Arch Gerontol Geriatr   Vol. 41 ( 2 ) page: 159-68   2005

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  268. 名古屋市保健所における痴呆介護予防事業参加者の意識調査

    藤城弘樹、梅垣宏行、鈴木裕介、中村 了、平川仁尚、井口昭久

    日老医誌   Vol. 42   page: 340-345   2005

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  269. Cognitive Function in Japanese Elderly with Type 2 Diabetes Mellitus Reviewed

    . Mogi N, Umegaki H, Hattori A, Maeda N, Miura H, Kuzuya M, Shimokata H, Ando F, Ito H, Iguchi A

    J Diabetes Complict   Vol. 18   page: 42-46   2004

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  270. DRD2 Gene Transfer Into the Nucleus Accumbens Core of the Alcohol Preferring and Nonpreferring Rats Attenuates Alcohol Drinking Reviewed

    Thanos PK , Rivera SN, Weaver K,. Grandy DK, Rubinstein M, Umegaki H , Wang GJ , Hitzemann R ,Volkow ND

    Alcohol Clin Exp Res   Vol. 5   page: 720-728   2004

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  271. The Relationship between Functional Disability and Depressive Mood in Japanese Older Adult Inpatients Reviewed

    Onishi J, Umegaki H, Suzuki Y, Uemura K, Kuzuya M, Iguchi A

    J Geriatr Psychiatr Neurol   Vol. 17 ( 2 ) page: 93-98   2004

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  272. The Clock Drawing Test as a Valid Screening Method for Mild Cognitive Impairment Reviewed

    Yamamoto S, Mogi N, Umegaki H, Suzuki Y, Ando F, Shimokata H, Iguchi A

    Dementi Geriatr Cogn   Vol. 18 ( 2 ) page: 172-179   2004

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  273. Smell identification test as an indicator for cognitive impairment in Alzheimer's disease. Reviewed

    Suzuki Y, Yamamoto S, Umegaki H, Onishi J, Mogi N, Fujishiro H, Iguchi A

    Int J Geriatr Psychiatry   Vol. 19 ( 8 ) page: 727-33   2004

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  274. 「高齢者医療の現状と展望」 最近のトピックス 諸外国における高齢者医療の現状

    遠藤英俊, 大島伸一, 三浦久幸, 大西丈二, 梅垣宏行, 鈴木裕介, 井口昭久

    日本内科学会雑誌   Vol. 93 ( 12 ) page: 2599-2602   2004

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  275. Longitudinal follow-up study of adenoviral vector-mediated gene transfer of dopamine D2 receptors in the striatum in young, middle-aged, and aged rats: a positron emission tomography study

    Umegaki H, Ishiwata K, Ogawa O, Ingram DK, Roth GS, Oda K, Kurotani S, Kawamura K, Wang WF, Ikari H, Senda M, Iguchi A

    Neuroscience   Vol. 121   page: 479-486   2003

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  276. Atrovastatin, 3-Hydroxy 3- Methylglutaryl Coenzyme A Reductase Inhibitor, reduces bone resorption in the elderly. Reviewed

    Kuzuya M, Suzuki Y, Asai T, Koike T, Kanda S, Nakamura A, Satake S, Umegaki H, Iguchi A

    JAGS   Vol. 51   page: 1677-1678   2003

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  277. The Age-Associated Changes of Dopamine-Acetylcholine Interaction in the Striatum. Reviewed

    Kurotani S, Umegaki H, Ishiwata K, Suzuki Y, Iguchi A

    Exp. Gerontol   Vol. 38/39   page: 1009-13   2003

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  278. Identification of factors associated with long hospital stay in Japanese geriatric ward Reviewed

    Umegaki H, Ando F, Shimokata H, Yamamoto S, Nakamura A, Endo H, Kuzuya M, Iguchi A.

    Geriatr Gerintol Int   Vol. 3 ( 2 ) page: 120-7   2003

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  279. Different glial reaction to hippocampal stab wounds in young adult and aged rats Reviewed

    Zhu W, Umegaki H, Shinkai T, Kurotani S, Suzuki Y, Endo H, Iguchi A

    J Gerontol A Biol Sci Med Sci   Vol. 58 ( 2 ) page: B117-22   2003

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  280. Involvement of the entorhinal cortex in the stress response to immobilization, but not to insulin-induced hypoglycemia Reviewed

    Umegaki H, Zhu W, Nakamura A, Suziki Y, Takada M, Endo H, Iguchi A

    J Neuroendocrinol   Vol. 15   page: 237-241   2003

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  281. In vivo assessment of adenoviral vector-mediated gene expression of dopamine D2 receptors in the rat striatum by positron emission tomography

    Umegaki H, Ishiwata K, Ogawa O., Ingram DK, Roth GS, Yoshimura J, Oda K, Matsui-Hirai H, Ikari H, Iguchi A, Senda M

    Synapse   Vol. 43   page: 195-200   2002

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  282. Plasma Insulin and Glucose Levels in Elderly Female Subjects with Alzheimer's Disease Reviewed

    Umegaki H, Ushida C, Ikari H, Ogawa O, Nakamura A, Suzuki Y, Endo H, Akatsu H, Yamamoto T, Iguchi A

    Geriatr Gerontol Int   Vol. 2   page: 75-9   2002

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  283. Positron emission tomography and ex vivo and in vitro autradiography studies on dopamin D2-like receptor degeneration in quinolinic acid- lesioned rat striatum. Reviewed

    Ishiwata K, Ogi N, Hayakawa N, Umegaki H, Nagaoka T, Oda K, Toyama H, Endo K, Tanaka A, Senda M

    Nuclear Medicine and biology   Vol. 29   page: 307-16   2002

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  284. Involvement of dopamine D2 receptor in complex maze and acetylcholine release in ventral hippocampus of rats Reviewed

    Umegaki H, Munoz J, Meyer RC, Spangler EL, Yoshimura J, Ikari H, Iguchi A, Ingram DK

    Neuroscience   Vol. 103 ( 1 ) page: 27-33   2001

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  285. Assessment of brain atrophy in elderly subjects with diabetes mellitus by computed tomography Reviewed

    Ushida C, Umegaki H, Hattori A, Mogi N, Aoki S, Iguchi A

    Geriatr Gerontol Int   Vol. 1   page: 33-7   2001

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  286. The elevation of plasma adrenocorticotrophic hormone and expression of c-Fos in hypothalamic paraventricular nucleus by microinjection of neostigmine into the hippocampus in rats: comparison with acute stress responses. Reviewed

    Zhu W, Umegaki H, Yoshimura J, Tamaya N, Suzuki Y, Miura H, Iguchi A

    Brain Res   Vol. 892 ( 2 ) page: 391-5   2001

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  287. Overexpression of dopamine D2 receptors reduces alcohol self-administration Reviewed

    Thanos PK, Volkow ND, Freimuth P, Umegaki H, Ikari H, Roth GS, Ingram DK, Hitzemann R

    J Neurochem   Vol. 78 ( 5 ) page: 1094-103   2001

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  288. Involvement of the bed nucleus of the stria terminalis in hippocampal cholinergic system-mediated activation of the hypothalamo-pituitary-adrenocortical axis in rats Reviewed

    Zhu W, Umegaki H, Suzuki Y, Miura H, Iguchi A

    Brain Res   Vol. 916   page: 101-6   2001

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  289. Dietary restriction of choline reduces hippocampal acetylcholine release in rats: in vivo microdialysis study. Reviewed

    Nakamura A, Suzuki Y, Umegaki H, Ikari H, Tajima T, Endo H, Iguchi A

    Brain Res Bull   Vol. 56 ( 6 ) page: 593-7   2001

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  290. The metabolism of plasma glucose and catecholamines in Alzheimer's disease Reviewed

    Umegaki H, Tamaya N, Shinkai T, Iguchi A

    Exp. Gerontol   Vol. 35 ( 9-10 ) page: 1373-82   2000

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  291. Low plasma epinephrine in elderly female subjects of dementia of Alzheimer's type. Reviewed

    Umegaki H, Ikari H, Nakahata H, Yoshimura J, Endo H, Yamamoto T, Iguchi A

    Brain Res   Vol. 858   page: 67-70   2000

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  292. In vivo imaging of adenovirus-mediated over-expression of dopamine D2 receptors in rat striatum by positron emission tomography Reviewed

    Ogawa O, Umegaki H, Ishiwata K, Asai Y, Ikari H, Oda K, Toyama H, Ingram DK, Roth G.S, Iguchi A, Senda M

    Neuroreport   Vol. 11 ( 4 ) page: 743-8   2000

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  293. Development of an adenoviral vector for intracerebral delivery of the dopamine D2 receptor. Reviewed

    Ingram DK, Umegaki H, Ikari H, Roth G.S

    Mech Ageing Dev   Vol. 116 ( 2-3 ) page: 77-93   2000

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  294. Plasma cortisol levels in elderly female subjects with Alzheimer's disease: a cross-sectional and longitudinal study. Reviewed

    Umegki H, Ikari H, Nakahata H, Endo H, Suzuki Y, Ogawa O, Nakamura A, Yamamoto T, Iguchi A

    Brain Res   Vol. 881 ( 2 ) page: 241-3   2000

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  295. Inhibition of inducible nitric oxide synthase gene expression by indomethacin or ibuprofen in beta-amyloid protein-stimulated J774 cells Reviewed

    Ogawa O, Umegaki H, Sumi D, Hayashi T, Nakamura A, Thakur NK, Yoshimura J, Endo H, Iguchi A

    Eur. J. Pharmacol   Vol. 408 ( 2 ) page: 137-41   2000

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  296. Dopamine induces apoptosis through an oxidation-involved SAPK/JNK activation pathway Reviewed

    Luo Y, Umegaki H, Wang X, Abe R, Roth GS

    J Biol Chem   Vol. 273 ( 6 ) page: 3756-64   1998

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  297. Application of Gene Therapy to Treat Age-Related Loss of Dopamine D2 Receptor Reviewed

    Ingram DK, Ikari H, Umegaki H, Chernak JM, Roth GS

    Exp. Gerontol   Vol. 33 ( 7-8 ) page: 793-804   1998

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  298. Intrastriatal injection of dopamine results in DNA damage and apoptosis in rats Reviewed

    Hattori A, Luo Y, Umegaki H, Munoz J, Roth GS

    Neuroreport   Vol. 9 ( 11 ) page: 2569-72   1998

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  299. Rotational behavior produced by adenovirus-mediated gene transfer of dopamine D2 receptor into rat striatum Reviewed

    Umegaki H, Chernak JM, Ikari H, Roth GS, Ingram DK

    Neuroreport   Vol. 8 ( 16 ) page: 3553-8   1997

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  300. Possible involvement of catalase in the protective effect of interleukin-6 against 6-hydroxydopamine toxicity in PC12 cells Reviewed

    Yamada K, Umegaki H, Maezawa I, Iguchi A, Kameyama T, Nabeshima T

    Brain Res. Bull   Vol. 43 ( 6 ) page: 573-7   1997

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  301. Nabeshima T. Protective effect of interleukin-6 against the death of PC12 cells caused by serum deprivation or by the addition of a calcium ionophore Reviewed

    Umegaki H, Yamada K, Naito M, Kameyama T, Iguchi A

    Biochem Pharmacol   Vol. 52 ( 6 ) page: 911-6   1996

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  302. Decreased interleukin-6 level in the cerebrospinal fluid of patients with Alzheimer-type dementia Reviewed

    Yamada K, Kono K, Umegaki H, Yamada K, Iguchi A, Fukatsu T, Nakashima N, Nishiwaki H, Shimada Y, Sugita Y, Yamamoto T, Hasegawa T, Nabeshima T

    Neurosci. Lett   Vol. 186 ( 2-3 ) page: 219-221   1995

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  303. Protective effects of probucol against glutamate-induced cytotoxicity in neuronal cell line PC12 Reviewed

    Naito M, Umegaki H, Iguchi A

    Neurosci. Lett   Vol. 186 ( 2-3 ) page: 211-3   1995

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Books 22

  1. すべての診療科で役立つ 栄養学と食事・栄養療法 第5章 ライフステージと栄養 4.高齢期

    中嶋宏貴,梅垣宏行( Role: Joint author)

    羊土社  2018.12 

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    Language:Japanese Book type:Scholarly book

  2. 糖尿病×○○○の診かた・考え方

    渡邊一久、梅垣宏行( Role: Joint author)

    南江堂  2018.5 

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  3. 高齢者総合診療ノート

    中嶋宏貴、梅垣宏行( Role: Joint author)

    日本医事新報社  2017.12 

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  4. 『ケースに学ぶ 高齢者糖尿病の診かた』第Ⅲ部 「22.認知症にはどう対応する?」「24.認知症では服薬回数を減らすべき?」

    梅垣宏行( Role: Sole author)

    ㈱南山堂  2017.4 

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    Language:Japanese Book type:Scholarly book

  5. 「高齢者理学療法学」 服薬確認

    梅垣宏行( Role: Sole author)

    医歯薬出版株式会社  2017.3 

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    Language:Japanese

  6. これからの在宅医療ガイド ―我々は被災地から何を学んだか― Ⅰ在宅医療は患者家族にとっていいものか? 在宅医療のQOL指標の開発、試用

    葛谷雅文・梅垣宏行( Role: Joint author)

    ㈱グリーン・プレス  2016.7 

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    Language:Japanese

  7. 『臨床栄養』別冊JCNセレクト「高齢者の健康寿命栄養戦略」 ・Ⅲ疾病予防・重症化予防 7.認知症.栄養・運動による認知症の発症・重症化予防.

    梅垣宏行( Role: Joint author)

    医歯薬出版株式会社  2016.4 

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  8. 『介護福祉士実務者研修テキスト 第4巻 発達と老化の理解・こころとからだのしくみ』 第1部「発達と老化の理解」第2章「老化に伴うこころとからだの変化と日常生活」

    梅垣宏行( Role: Sole author)

    社会福祉法人 全国社会福祉協議会  2016.3 

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    Language:Japanese

  9. 『病気とくすり』・認知症.

    梅垣宏行( Role: Joint author)

    南山堂  2016.3 

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    Language:Japanese

  10. 糖尿病ケア・ 特集 患者さんと医療者の不安を解決 認知症なんでもQ&A.・認知症を予防するために何をすればよいですか。・認知症になったらもう治療法はないのですか。

    梅垣宏行( Role: Joint author)

    メディカ出版  2016.1 

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    Language:Japanese

  11. これからの在宅医療ガイド ―我々は被災地から何を学んだか― 在宅医療のQOL指標の開発、試用

    大島真一 他 葛谷雅文、梅垣宏行( Role: Joint author)

    ㈱グリーン・プレス  2016 

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  12. “最新研究”から“医療者&患者さんのギモン”まで ◎患者さんの疑問編 3.4.

    梅垣宏行( Role: Sole author)

    糖尿病ケア誌  2015.12 

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  13. ココに注意!高齢者の糖尿病 老年症候群を考えた治療とQOLを高める療養指導のコツ

    荒木 厚/編( Role: Joint author)

    羊土社  2015.1 

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  14. 『かかりつけ医のための老年病100の解決法』急に血糖コントロールの悪化した糖尿病患者への対応について

    梅垣宏行( Role: Sole author)

    メディカルレビュー社  2015 

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  15. フレイルティ -高齢社会における最重要課題と予防戦略

    葛谷雅文 他( Role: Joint author)

    医歯薬出版株式会社  2014.6 

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  16. 治療が劇的にうまくいく!高齢者の栄養 はじめの一歩 身体機能を低下させない疾患ごとの栄養管理のポイント

    大村健二,葛谷雅文 他( Role: Joint author)

    羊土社  2013.2 

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  17. 高齢者のための薬の使いかた ストップとスタート

    秋下 雅弘 他( Role: Joint author)

    ぱーそん書房  2013 

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    Language:Japanese

  18. 機能性食品素材と運動療法―生活習慣病予防と運動機能維持、向上をめざして―

    大澤俊彦・佐藤祐造他( Role: Joint author)

    シーエムシー出版  2012.6 

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  19. 老年医学up date 2009-10

    小原克彦、斎藤重幸 他( Role: Joint author)

    MEDICAL VIEW社  2009.6 

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    Language:Japanese

  20. 老年医学テキスト 改訂版

    社団法人 日本老年医学会( Role: Joint author)

    メジカルビュー社  2008.6 

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  21. ベッドサイドの高齢者の診かた

    葛谷雅文, 秋下雅弘 他( Role: Joint author)

    南山堂  2008.3 

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  22. 次世代の医学・医療がわかる 未病医学 入門

    都島基夫、福生吉宏他( Role: Joint author)

    金芳堂  2006 

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▼display all

Presentations 57

  1. 身体的フレイルと認知症

    梅垣宏行

    第34回日本臨床リウマチ学会 

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    Event date: 2019.11 - 2019.12

    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Venue:名古屋市   Country:Japan  

  2. 認知症患者の糖尿病治療

    梅垣宏行

    第38回 日本認知症学会 

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    Event date: 2019.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京   Country:Japan  

  3. 健康的な食事でフレイル・認知症を予防しようー健康寿命の延伸と栄養―

    梅垣宏行

    第41回日本臨床栄養学会総会・第40回日本臨床栄養協会総会 第17回大連合大会 

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    Event date: 2019.10

    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Venue:名古屋   Country:Japan  

  4. 糖尿病における認知機能悪化予防のための生活習慣介入

    梅垣宏行

    第34回日本糖尿病合併症学会・第25回日本糖尿病眼学会総会 

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    Event date: 2019.9

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:大阪市   Country:Japan  

  5. 医療介護のアウトカム評価

    梅垣宏行、岩佐 一、深井穫博、竹内孝仁

    第61回日本老年医学会学術集会 

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    Event date: 2019.6

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:仙台   Country:Japan  

  6. 地域在住高齢者の身体活動量と転倒恐怖感との関連の検討

    梅垣宏行、牧野多恵子、上村一貴、葛谷雅文

    第61回日本老年医学会学術集会 

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    Event date: 2019.6

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:仙台   Country:Japan  

  7. 高齢糖尿病患者の薬物療法の注意点

    梅垣宏行

    第3回 老年薬学会 

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    Event date: 2019.5

    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Venue:名古屋市   Country:Japan  

  8. フレイルと認知症

    梅垣宏行

    第63回 日本リユウマチ学会総会・学術集会 

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    Event date: 2019.4

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:京都   Country:Japan  

  9. 社会的孤立と認知機能の関連の検討

    梅垣宏行、牧野多恵子、葛谷雅文

    第37回日本認知症学会学術集会  

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    Event date: 2018.10

    Language:Japanese   Presentation type:Poster presentation  

    Venue:札幌   Country:Japan  

  10. ファシリテーター

    梅垣宏行

    高齢者医療研修会 

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    Event date: 2018.6

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    Venue:京都   Country:Japan  

  11. 在宅高齢者における不適切処方と入院との関連の検討

    梅垣宏行、野村秀樹、神田 茂、紙谷博子、渡邉雄貴、中嶋宏貴、小宮 仁、渡邊一久、葛谷雅文

    第60回日本老年医学会学術集会 

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    Event date: 2018.6

    Language:Japanese   Presentation type:Poster presentation  

    Venue:京都   Country:Japan  

  12. 地域在住高齢者におけるプレフレイルと転倒の関連に関する検討

    梅垣宏行、牧野多恵子、上村一貴、島田裕之、葛谷雅文

    第60回日本老年医学会学術集会 

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    Event date: 2018.6

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:京都   Country:Japan  

  13. 高齢者のインスリン抵抗性と身体活動量の関連

    梅垣宏行、牧野多恵子、渡邉 一久、葛谷 雅文

    第61回日本糖尿病学会年次学術集会 

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    Event date: 2018.5

    Language:Japanese   Presentation type:Poster presentation  

    Venue:東京都   Country:Japan  

  14. 高齢糖尿病患者の血圧・脂質管理

    梅垣宏行

    第52回糖尿病学の進歩 

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    Event date: 2018.3

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:福岡市   Country:Japan  

  15. MCIから軽度AD患者の認知機能とQOLの関連

    梅垣宏行、紙谷博子、牧野多恵子、栁川まどか、葛谷雅文、櫻井 孝

    第36回日本認知症学会学術集会 

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    Event date: 2017.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:金沢   Country:Japan  

  16. 他領域での認知症予防

    梅垣宏行

    日本認知症予防学会 学術集会 

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    Event date: 2017.9

    Language:Japanese  

    Venue:岡山   Country:Japan  

  17. フレイルな高齢糖尿病患者の病態と治療

    梅垣宏行

    第22回日本糖尿病教育・看護学会 学術集会 

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    Event date: 2017.9

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:福岡   Country:Japan  

  18. 訪問診療をうける高齢者の栄養状態の悪化に関する因子の検討

    梅垣宏行、浅井真嗣、神田茂、野村秀樹、前田恵子、下島卓弥、葛谷雅文

    第19回 日本在宅医学会大会 

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    Event date: 2017.6

    Language:English   Presentation type:Oral presentation (general)  

    Venue:名古屋市   Country:Japan  

  19. 認知機能障害と身体機能・身体組成の関連

    梅垣宏行、牧野多恵子、栁川まどか、中嶋宏貴、小宮 仁、葛谷雅文

    第59回日本老年医学会学術集会 

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    Event date: 2017.6

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:名古屋市   Country:Japan  

  20. 地域での認知症予防のための栄養指導

    第59回日本老年医学会学術集会

    地域での認知症予防のための栄養指導 

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    Event date: 2017.6

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:名古屋市   Country:Japan  

  21. 訪問診療をうける高齢者のQOLに関連する因子の検討

    梅垣宏行、紙谷博子、神田茂、野村秀樹、前田恵子、葛谷雅文

    第59回日本老年医学会学術集会 

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    Event date: 2017.6

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:名古屋市   Country:Japan  

  22. 高齢糖尿病患者のフレイルと認知機能の関連

    梅垣宏行、牧野多恵子、林尊弘、葛谷雅文

    第60回日本糖尿病学会年次学術集会 

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    Event date: 2017.5

    Language:Japanese   Presentation type:Poster presentation  

    Venue:名古屋市   Country:Japan  

  23. フレイルな高齢者への栄養・運動療法

    梅垣宏行

    第20回日本病態栄養学会年次学術集会 

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    Event date: 2017.1

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    Country:Japan  

  24. 地域在住高齢者におけるインスリン抵抗性と認知機能の関連

    梅垣 宏行、牧野 多恵子、上村一貴、島田 裕之、葛谷 雅文

    第35回 日本認知症学会学術集会 

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    Event date: 2016.12

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  25. 「在宅医療における生活習慣病ならびに疾病管理基準-ガイドラインとの整合性と抱えている課題」 在宅医療における糖尿病管理

    梅垣宏行

    第18回 日本在宅医学会大会 第21回 日本在宅ケア学会学術集会合同大会 

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    Event date: 2016.7

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  26. 非癌在宅医療受療者における入院および死亡の関連因子の検討

    梅垣宏行、神田 茂、野村秀樹、前田恵子、葛谷雅文

    第58回 日本老年医学会学術集会 

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    Event date: 2016.6

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  27. 高齢糖尿病患者の認知機能低下と血糖・血圧コントロールの関係―9 年間の観察研究

    梅垣宏行

    第59回 日本糖尿病学会年次学術集会 

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    Event date: 2016.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  28. 高齢者におけるサルコペニア・フレイル

    梅垣宏行

    第20回日本体力医学会東海地方会学術集会 

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    Event date: 2016.3

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    Country:Japan  

  29. 糖尿病患者の認知機能障害

    梅垣宏行

    第30回日本糖尿病合併症学会 

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    Event date: 2015.11

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Venue:名古屋市   Country:Japan  

  30. 在宅医療をうける高齢者における在宅医療の中断に関する認知症の影響―ONEHOME研究

    梅垣宏行、浅井真嗣、神田茂、野村秀樹、前田恵子、葛谷雅文

    第34回日本認知症学会学術集会 

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    Event date: 2015.10

    Language:Japanese   Presentation type:Poster presentation  

    Venue:青森市   Country:Japan  

  31. 教育企画『地域包括ケア実現に向けての課題と対策』

    梅垣宏行

    第26回日本老年医学会東海地方会 

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    Event date: 2015.9

    Language:Japanese  

    Venue:名古屋市   Country:Japan  

  32. 認知機能

    梅垣宏行

    第5回日本認知症予防学会学術集会 

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    Event date: 2015.9

    Language:Japanese  

    Venue:神戸市   Country:Japan  

  33. SPECT Findings and Neuropsychological Assessments in Older Alzheimer's Disease International conference

    Hiroyuki Umegaki

    SPECT Findings and Neuropsychological Assessments in Older Alzheimer's Disease 

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    Event date: 2015.7

    Language:English   Presentation type:Poster presentation  

    Country:United States  

  34. 在宅医療における入院・入所・死亡に関連する因子の検討

    梅垣宏行、野村秀樹、神田 茂、前田恵子、小笠原真雄、神谷博子、鈴木裕介、葛谷雅文

    第57回日本老年医学会学術集会 

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    Event date: 2015.6

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:横浜   Country:Japan  

  35. 在宅医療をうける高齢者における最近の入院に対する糖尿病の影響

    梅垣宏行、浅井真嗣、神田茂、野村秀樹、下島卓也、前田恵子、小笠原文雄、葛谷雅文 

    第58回日本糖尿病学会年次学術集会 

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    Event date: 2015.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:下関市   Country:Japan  

  36. 高齢糖尿病患者におけるサルコペニア・フレイル・ADL低下

    梅垣宏行

    第58回日本糖尿病学会年次学術集会 

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    Event date: 2015.5

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:下関市   Country:Japan  

  37. アルツハイマー型認知症の認知機能への糖尿病の合併の影響

    梅垣宏行、牧野多恵子、一柳知里、葛谷雅文

    第58回日本糖尿病学会年次学術集会 

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    Event date: 2015.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:下関市   Country:Japan  

  38. 在宅医療におけるQOL評価のための評価表の作成

    梅垣宏行

    第17回 日本在宅医学会もりおか大会 

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    Event date: 2015.4

    Language:Japanese   Presentation type:Poster presentation  

    Venue:盛岡市   Country:Japan  

  39. これからの高齢者糖尿病医療に必要な知識とスキル

    梅垣宏行

    第49回 糖尿病学の進歩 

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    Event date: 2015.2

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:岡山   Country:Japan  

  40. 超高齢社会におけるサルコペニア、フレイルの意義を問う

    梅垣宏行

    第1回日本サルコペニア・フレイル研究会研究発表会 

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    Event date: 2014.10

    Language:Japanese  

    Country:Japan  

  41. The prevalence of homebound individuals in the elderly population: A survey in a city area in Japan. International conference

    10th Interntional Congress of the European Union Geriatric Medicine Society 

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    Event date: 2014.9

    Language:English   Presentation type:Poster presentation  

    Country:Netherlands  

  42. 高齢者と認知・判断・行動

    梅垣宏行

    第23回 日本交通医学工学研究会 学術総会 

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    Event date: 2014.9

    Language:Japanese  

    Country:Japan  

  43. Treatment of elderly with diabetes: Cognitive dysfunction International conference

    The 20th IAGG World Congress of Gerontology and Geriatrics 

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    Event date: 2013

    Language:English   Presentation type:Symposium, workshop panel (public)  

    Country:Japan  

  44. The perception of dementia in general population in Japan International conference

    Alzheimer's Association International Conference 

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    Event date: 2013

    Language:English   Presentation type:Poster presentation  

    Country:United States  

  45. 教育企画「高齢者の介護・看護・医療」

    梅垣宏行

    第23回日本老年医学会東海地方会 

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    Event date: 2012.10

    Language:Japanese  

    Venue:名古屋   Country:Japan  

  46. 特定高齢者における認知機能低下と転倒との関連

    梅垣宏行、柳川まどか、野々垣 禅、中嶋宏貴、葛谷雅文

    日本認知症予防学会学術集会 

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    Event date: 2012.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:北九州市   Country:Japan  

  47. 高齢者糖尿病の管理―J-EDIT研究から得られたもの―

    梅垣宏行

    第54回日本老年医学会学術集会 

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    Event date: 2012.6

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:東京   Country:Japan  

  48. 認知症予防の最前線―現在そして将来、どこまでできるか

    梅垣宏行

    第18回日本未病システム学会学術総会 

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    Event date: 2011.11

    Language:Japanese  

    Venue:名古屋   Country:Japan  

  49. 特定高齢者の認知機能低下に関連する因子の検討

    梅垣宏行、鈴木裕介、遠藤英俊

    第30回日本認知症学会学術集会 

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    Event date: 2011.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京   Country:Japan  

  50. アルツハイマー型認知症患者の生活習慣病とsmall-vessel diseaseの認知機能への影響

    梅垣宏行、牧野多恵子、鈴木裕介、山本さやか、河野直子

    第30回日本認知症学会学術集会 

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    Event date: 2011.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京   Country:Japan  

  51. 特定高齢者の嚥下機能低下に関連する因子の検討

    梅垣宏行、柳川まどか、野々垣 禅、遠藤英俊

    第53回日本老年医学会学術集会 

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    Event date: 2011.6

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京   Country:Japan  

  52. 高齢糖尿病患者の認知機能低下に関連する因子の検討(J-EDIT study)

    梅垣宏行、飯室 聡、荒木 厚、櫻井 孝、飯島勝矢、井藤英喜

    第53回日本老年医学会学術集会 

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    Event date: 2011.6

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京   Country:Japan  

  53. 認知機能障害と糖尿病

    梅垣宏行

    第32回日本臨床栄養学会総会・第31回日本臨床栄養協会総会 

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    Event date: 2010.8

    Language:Japanese  

    Venue:名古屋   Country:Japan  

  54. 特定高齢者の転倒に関連する因子の検討

    梅垣宏行

    第52回日本老年医学会学術集会 

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    Event date: 2010.6

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:神戸   Country:Japan  

  55. Driving problems arising from dementia and various cognitive impairment International conference

    22nd annual meeting of JPS, 26th annual meeting of JSDR 

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    Event date: 2007

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  56. The impaired imitation of meaningless-movement in mild cognitive impairment and early-stage Alzheimer's disease International conference

    22nd annual meeting of JPS, 26th annual meeting of JSDR 

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    Event date: 2007

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  57. Strategy for Prevention of Alzheimer's Disease International conference

    Umegaki H

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    Event date: 2005.5

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

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Research Project for Joint Research, Competitive Funding, etc. 35

  1. 認知症予防を目指した多因子介入によるランダム化比較研究

    2019.6

    長寿医療研究委託費 

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    Grant type:Competitive

  2. 高齢者における聴覚障害と総合機能・認知機能の包括的評価:難聴補正による認知症予防を目指した研究

    2018 - 2021

    長寿医療研究委託費 

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    Grant type:Competitive

  3. 日本人の前期高齢者における実態等に関する調査・研究等のレビュー

    2018

    長寿医療研究委託費 

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    Grant type:Competitive

  4. 高齢者の認知機能低下に配慮した至適血圧域の解明:老年期にある健常者と経度認知機能低下患者を対象とした、認知機能保持ないしその改善を最終目的とした、適切な血圧管理法に関する研究

    2018

    長寿医療研究委託費 

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    Grant type:Competitive

  5. レジストリーデーターに基づいた経口抗擬固薬を適切に選択するための研究(Strawberry研究)

    2017.11 - 2023.3

    長寿医療研究委託費 

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    Grant type:Competitive

  6. 高齢者における聴覚障害と総合機能・認知機能の包括的評:難聴補正による認知症予防を目指した調査研究

    2017.7 - 2018.3

    科学技術振興調整費 

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    Grant type:Competitive

  7. 齢者2型糖尿病における認知症予防のための多因子介入研究―パイロット研究―

    2017 - 2020.3

    長寿医療研究委託費 

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    Grant type:Competitive

  8. 「認知症の当事者・家族の視点にもとづく療養指導のためのエビデンス構築研究

    2016.4 - 2017.3

    長寿医療研究委託費 

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    Grant type:Competitive

  9. 在宅医療をうける高齢糖尿病患者のQuality of Life(QOL)の検討

    2015.4 - 2016.3

    学内共同研究 

  10. 日本人における大脳白質病変の老年症候群に及ぼす作用と危険因子の解明に関する研究

    2014.4 - 2015.3

    長寿医療研究委託費 

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    Grant type:Competitive

  11. 食シグナルの認知科学の新展開と脳を活性化する次世代機能性食品開発へのグランドデザイン

    2014 - 2017

    国内共同研究 

    遠藤英俊、梅垣宏行

  12. 認知症非薬物療法の普及促進介入による介護負担の軽減、住宅維持率向上の地域包括的

    2013.4 - 2015.3

    科学技術振興調整費 

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    Grant type:Competitive

  13. 保険指導等を活用した総合的な糖尿病治療の年代別要因を踏まえた研究

    2012.4 - 2015.3

    科学技術振興調整費 

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    Grant type:Competitive

  14. 地域・在宅高齢者における摂食嚥下・栄養障害に関する研究 ―特にそれが及ぼす在宅療養の非継続性と地域における介入・システム構築に向けて―

    2012.4 - 2015.3

    科学技術振興調整費 

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    Grant type:Competitive

  15. 糖尿病患者における心血管イベント発症に関する後ろ向きコホートに関する研究

    2009.4 - 2012.3

    科学技術振興調整費 

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    Grant type:Competitive

  16. 老年医学的総合機能評価(CGA)の研究開発及びCGA活用による地域連携の推進のための高齢者医療連携システムの開発

    2009.4 - 2012.3

    長寿医療研究委託費 

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    Grant type:Competitive

  17. 在宅高齢者の移動手段選択理由に関する調査

    2008.4 - 2009.3

    学内共同研究 

  18. 高齢ドライバーにおける認知機能低下が車体操作の技能に及ぼす影響の検証

    2007.4 - 2008.3

    学内共同研究 

  19. 糖尿病に伴う認知機能障害に対する運動療法による介入効果の検討

    2007.4 - 2008.3

    学内共同研究 

  20. 高齢者糖尿病を対象とした前向き大規模臨床介入研究(J-EDIT)

    2007.4 - 2008.3

    国内共同研究 

  21. 高齢者包括的・全人的医療に関わる標準的医療システムの開発に関する研究

    2006.4 - 2009.3

    長寿医療研究委託費 

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    Grant type:Competitive

  22. 糖尿病に伴う認知機能障害に対する運動療法による介入効果の検討

    2006.4 - 2007.4

    学内共同研究 

  23. 高齢者糖尿病に対する総合診療体制確立のための総合的研究―無作為化比較研究(J-EDIT)を中心に

    2005.4 - 2007.3

    科学技術振興調整費 

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    Grant type:Competitive

  24. DLBの診断治療に関する総合的研究

    2005.4 - 2007.3

    企業からの受託研究 

  25. 高齢者糖尿病患者の認知機能低下におけるインスリン抵抗性の関与の検討

    2005.4 - 2006.3

    学内共同研究 

  26. 各種高脂血症治療薬の糖尿病性心血管病進展予防効果の総合的検討

    2004.4 - 2007.3

    科学技術振興調整費 

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    Grant type:Competitive

  27. 痴呆性高齢者におけるケアサービスの質的評価に関する研究

    2004.4 - 2006.3

    科学技術振興調整費 

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    Grant type:Competitive

  28. 高齢糖尿病患者における認知機能低下の発症機序の解明

    2004.4 - 2005.3

    学内共同研究 

  29. 高齢者総合機能評価と包括医療の確立に関する研究

    2003.4 - 2006.3

    長寿医療研究委託費 

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    Grant type:Competitive

  30. 一般病床における痴呆性高齢者のクリティカルパスの作成に関する研究

    2001.4 - 2004.3

    科学技術振興調整費 

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    Grant type:Competitive

  31. 痴呆性高齢者の認知機能障害の改善に関する国際共同研究

    2001.4 - 2004.3

    長寿科学国際共同研究事業 

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    Grant type:Competitive

  32. 高齢糖尿病を対象とした前向き大規模臨床介入試験

    2000.4 - 2003.3

    科学技術振興調整費 

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    Grant type:Competitive

  33. 口腔保健と全身的な健康状態の関係

    1999.4 - 2002.3

    科学技術振興調整費 

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    Grant type:Competitive

  34. 遺伝子導入を用いたアルツハイマー型痴呆症の成因の基礎的検討

    1998.4 - 2000.3

    学内共同研究 

  35. 老年性痴呆患者のケアに関する総合的研究

    1997.4 - 2000.3

    科学技術振興調整費 

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    Grant type:Competitive

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KAKENHI (Grants-in-Aid for Scientific Research) 18

  1. フレイルインデックス開発のためのコホート研究

    Grant number:21H02826  2021.4 - 2025.3

    科学研究費助成事業  基盤研究(B)

    梅垣 宏行, 佐竹 昭介, 亀山 祐美, 竹屋 泰

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    Authorship:Principal investigator 

    Grant amount:\15860000 ( Direct Cost: \12200000 、 Indirect Cost:\3660000 )

    入院時にフレイルの把握をすることは重要である。しかしながら、急性期入院時にフレイルの診断をすることは必ずしも容易ではないため、その概念の浸透にもかかわらず、医療の現場ではフレイル診断が広く普及しているとはいえない。
    我が国の診療環境において正確な予後推定を可能とし、かつ、簡易な診療情報のみから算出可能なFIを開発することを主たる目的として、全国4施設の老年内科病棟の急性期入院患者の前向きコホート研究を実施する。

  2. サルコペニア患者に対する腸内細菌叢への介入による効果的な運動療法の開発

    Grant number:21K11261  2021.4 - 2024.3

    科学研究費助成事業  基盤研究(C)

    石津 洋二, 本多 隆, 梅垣 宏行, 山本 健太

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    Authorship:Coinvestigator(s) 

    サルコペニアに対する治療は運動療法であるが、十分な効果を得られないことが多い。近年、腸内細菌が産生する短鎖脂肪酸が骨格筋と関係している事が明らかになった。短鎖脂肪酸は腸内環境を整えることで炎症を抑え、それにより骨格筋の分解を抑える働きを持つ。さらに筋肉におけるエネルギー代謝にも関連し、運動時の易疲労性に対し予防的に働く。以上のことから、運動療法に短鎖脂肪酸産生を増加させるような腸内細菌叢への介入を加えることで、運動療法の効果を増強できるのではないかと考えた。そこで本研究は、サルコペニアに対し、腸内細菌叢への介入による効果的な運動療法を開発することを目的とする。

  3. Elucidation of the mechanism of the cognitive functional decline protective efficacy by the exercise

    Grant number:15K08908  2015.4 - 2019.3

    YANAGAWA MADOKA

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    Authorship:Coinvestigator(s) 

    It is necessary to clarify the characteristic that is in a state called preclinical AD to prevent the onset of AD. I call the state that only power to memorize decreases MCI and call a stage only with conscious forgetfulness more with SCI for a pre-stage. And it’s suggested that exercise may be a better way to prevent dementia, thought its mechanism is unclear.We examined the cognitive protection effect of exercise before and after exercise intervention in patients of MCI, I was going to perform a similar examination for the patients of SCI , but careful correspondence is necessary about the CSF collection of the study concerned .And it is difficult unexpectedly to gather a cerebrospinal fluid from a patient of healthy SCI, and what cannot possibly achieve the number of the aims becomes clear. In addition, similar results of research were given by each country and did decision to stop a study because significant difference appeared neither..

  4. 運動による認知機能低下予防効果の機序の解明

    2015.4 - 2018.3

    科学研究費補助金  基盤研究(C)

    柳川まどか

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    Authorship:Coinvestigator(s) 

  5. インスリン抵抗性に着目したアルツハイマー病バイオマーカーの縦断的研究

    2015.4 - 2018.3

    科学研究費補助金  基盤研究(C)

    梅垣宏行

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    Authorship:Principal investigator 

  6. Investigation of the mechanism of acceleration of Alzheimer disease-related neuropathology by insulin resistance

    Grant number:15K08907  2015.4 - 2018.3

    UMEGAKI Hiroyuki

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    Authorship:Principal investigator 

    Grant amount:\4810000 ( Direct Cost: \3700000 、 Indirect Cost:\1110000 )

    Past studies suggested that insulin resistance (IR) may be involved in the mechanism of cognitive impairment in the older subjects. In the current study we studied the association of IR and cognitive function in the older subjects with mild cognitive decline. The number of 40 subjects was involved in the analysis. All the subjects had the assessments of fasting serum glucose and insulin with several cognitive assessments including Mini Mental State Examination (MMSE). The subjects were divided into 2 groups according to the score of MMSE at the cut-off of 23/24. The level of serum insulin was statistically significantly higher in the lower MMSE group than the higher group, while there was no difference in glucose and HbA1c levels. The results suggested that IR is associated with cognitive dysfunction in the older subjects.

  7. The development of a program intended to improve quality of life by a combination therapy (music and exercise) for dementia patients and caregivers.

    Grant number:26670369  2014.4 - 2018.3

    Hirano Akemi

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    Authorship:Other 

    This study aimed to determine whether an activity program that incorporates music/exercise therapy and caregivers of patients with dementia can reduce stress associated with caregiving, and whether carrying out the program at home can improve levels of atherosclerosis promoting factors such as adiponectin, homocysteine, and high sensitivity C-reactive protein. Participants were elderly caregivers and patients with Alzheimer-type dementia. The intervention group took part in an activity program that incorporated music/exercise therapy (20 minutes/twice a week/3months), while the control group carried on with routine daily care.
    There were 42 participating caregiver, and levels of adiponectin and homocysteine improved in caregivers of both intervention and control groups. GDS improved significantly in the intervention group, but did not change in the control group. While the ZBI score did not significantly change in the intervention group, it significantly worsened in the control group.

  8. 抗認知症薬の経鼻投与の効果・臨床応用への可能性の検討

    2012.4 - 2015.3

    科学研究費補助金  基盤研究(C)

    鈴木祐介

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    Authorship:Coinvestigator(s) 

  9. 運動による認知機能改善効果の機序の解明

    2012.4 - 2015.3

    科学研究費補助金  基盤研究(C)

    柳川まどか

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    Authorship:Coinvestigator(s) 

  10. 細胞老化制御による進行動脈硬化症治療―本邦高齢者へのオーダーメイド治療を目指す―

    2009.4 - 2012.3

    科学研究費補助金  基盤研究(C)

    林 登志雄

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    Authorship:Coinvestigator(s) 

  11. アルツハイマー病における自律神経機能評価などによる中枢神経機能評価の試み

    2009.4 - 2012.3

    科学研究費補助金  基盤研究(C)

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    Authorship:Principal investigator 

  12. 高齢女性の動脈硬化性疾患予防と健康長寿を目指すアジア老年医学研究

    2008.4 - 2010.3

    科学研究費補助金  基盤研究(B)

    林 登志雄

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    Authorship:Coinvestigator(s) 

  13. 一酸化窒素、活性酸素制御を介する血管内分泌及び血管老化制御による動脈硬化退縮療法

    2007.4 - 2009.3

    科学研究費補助金  基盤研究(C)

    林 登志雄

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    Authorship:Coinvestigator(s) 

  14. DLBの診断治療に関する総合的研究

    2005.4 - 2008.3

    科学研究費補助金  基盤研究(C)

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    Authorship:Principal investigator 

  15. レビー小体型痴呆の診断治療に関する総合的研究

    2005.4 - 2006.3

    科学研究費補助金  基盤研究(C)

    梅垣 宏行

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    Authorship:Principal investigator 

  16. アルツハイマー型痴呆症における自律神経系障害の発症機序の基礎的検討

    2003.4 - 2005.3

    科学研究費補助金  若手研究(B)

    梅垣 宏行

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    Authorship:Principal investigator 

  17. ドーパミンD2受容体の遺伝子導入による記憶障害治療の試み

    2002.4 - 2004.3

    科学研究費補助金 

    井口昭久

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    Authorship:Coinvestigator(s) 

  18. 遺伝子導入によるラット脳ドパミン受容体発現のポジトロン断層法によるインビボ測定

    1998.4 - 2000.3

    科学研究費補助金  基盤研究(B)

    石渡喜一

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    Authorship:Coinvestigator(s) 

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