Updated on 2022/05/23

写真a

 
SONE, Michihiko
 
Organization
Graduate School of Medicine Program in Integrated Medicine Head and Neck and Sensory Organ Medicine Professor
Graduate School
Graduate School of Medicine
Undergraduate School
School of Medicine Department of Medicine
Title
Professor
Contact information
メールアドレス

Degree 1

  1. 博士(医学) ( 1995.3   名古屋大学 ) 

Research Interests 5

  1. gastroesophageal reflux

  2. tympanoplasty

  3. cochlear endoscopy

  4. inner ear disturbance

  5. middle ear disease

Research Areas 1

  1. Others / Others  / Otorhinolaryngology

Current Research Project and SDGs 1

  1. mechanisms of the middle/inner ear functiontympanoplastycochlear implant

Education 2

  1. Nagoya University   Graduate School, Division of Medical Sciences

    1991.4 - 1995.3

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    Country: Japan

  2. Nagoya University   Faculty of Medicine

    1981.4 - 1987.3

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    Country: Japan

Professional Memberships 12

  1. 日本耳鼻咽喉科学会   代議員

    2005.4

  2. Otology Japan

    2018.10

  3. Audiology Japan

    2016.10

  4. 耳鼻咽喉科臨床学会   編集委員

    2005.11

  5. 日本気管食道科学会   評議員

    2012.9

  6. 日本頭頸部外科学会   評議員

    2016.2

  7. 日本免疫アレルギー学会   評議員

    2016.9

  8. 日本頭頸部癌学会

  9. めまい平衡医学会

  10. ARO

  11. 日本口腔咽頭科学会   評議員

    2016.10

  12. 日本嚥下医学会   評議員

    2016.9

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Awards 2

  1. 第13回GERD研究会特別奨励賞

    2008.11  

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    Country:Japan

  2. 愛知県難病研究者表彰

    2003.10   愛知県医師会  

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    Country:Japan

 

Papers 105

  1. Otological aspects of Fabry disease in patients with normal hearing

    Wang Fei, Yamamoto Hiroshi, Yoshida Tadao, Sugimoto Satofumi, Teranishi Masaaki, Tsuboi Kazuya, Sone Michihiko

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 81 ( 3 ) page: 469 - 475   2019.8

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.18999/nagjms.81.3.469

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  2. Endolymphatic hydrops in superior canal dehiscence and large vestibular aqueduct syndromes Reviewed

    Sone M, Yoshida T, Morimoto K, Teranishi M, Nakashima T, Naganawa S.

    Laryngoscope   Vol. 126   page: 1446–1450   2016.6

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  3. Current concepts of otitis media in adults as a reflux-related disease. Reviewed

    Sone M, Kato T, Nakashima T.

    Otology & Neurotology   Vol. 36 ( 6 ) page: 1013-1017   2013.12

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  4. Comparison of CT and MRI for evaluation of cholesteatoma with labyrinthine fistulae. Reviewed

    Sone M, Yoshida T, Naganawa S, Otake H, Kato K, Sano R, Teranishi M, Nakashima T.

    Laryngoscope   Vol. 122 ( 5 ) page: 1121-1125   2012.5

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  5. Detection of IV-gadolinium Leakage from the Cortical Veins into the CSF Using MR Fingerprinting.

    Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine   Vol. 19 ( 2 ) page: 141 - 146   2020

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.2463/mrms.mp.2019-0048

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  6. A plea for systematic literature analysis and conclusive study design, comment on: "Systematic review of magnetic resonance imaging for diagnosis of Meniere disease".

    Journal of vestibular research : equilibrium & orientation     2019.6

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3233/VES-190662

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  7. Difference in Serum Levels of Vitamin D Between Canalolithiasis and Cupulolithiasis of the Horizontal Semicircular Canal in Benign Paroxysmal Positional Vertigo

    Nakada Takafumi, Sugiura Saiko, Uchida Yasue, Suzuki Hirokazu, Teranishi Masaaki, Sone Michihiko

    FRONTIERS IN NEUROLOGY   Vol. 10   page: 176   2019.3

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.3389/fneur.2019.00176

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  8. *Changes in endolymphatic hydrops in a patient with Meniere's disease observed using magnetic resonance imaging Reviewed

    Sone M, Naganawa S, Teranishi M, Nakata S, KatayamaN, Nakashima T

    Auris Nasus Larynx   Vol. 37   page: 220-222   2010

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  9. Age-related hearing loss and cognitive decline - The potential mechanisms linking the two.

    Uchida Y, Sugiura S, Nishita Y, Saji N, Sone M, Ueda H

    Auris, nasus, larynx   Vol. 46 ( 1 ) page: 1 - 9   2019.2

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.anl.2018.08.010

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  10. *Imaging analysis in cases with inflammation-induced sensorineural hearing loss Reviewed

    Sone M, Mizuno T, Naganawa S, Nakashima T

    Acta Otolaryngol   Vol. 129   page: 239-243   2009

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  11. Mixed cellular inflammation is increased in adult asthma with severe chronic rhinosinusitis

    Nishio Tomoko, Wakahara Keiko, Suzuki Yoshihiro, Majima Suguru, Nishio Naoki, Teranishi Masaaki, Sone Michihiko, Hasegawa Yoshinori

    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY   Vol. 143 ( 2 ) page: AB189-AB189   2019.2

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    Language:English   Publishing type:Research paper (scientific journal)  

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  12. *Otitis media in adults as a symptom of gastroesophageal reflux

    Michihiko Sone, Yuri Yamamuro, Hideo Hayashi, Yasumasa Niwa, Tsutomu Nakashima

    Otolaryngol Head Neck Surg   Vol. 136   page: 19-22   2007

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  13. Significance of internal auditory canal diverticula in ears with otosclerosis.

    Wang F, Yoshida T, Shimono M, Sugimoto S, Teranishi M, Naganawa S, Sone M

    Acta oto-laryngologica     page: 1-4   2019.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1080/00016489.2018.1521526

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  14. *Three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging investigation of inner ear disturbances in cases of middle ear cholesteatoma with labyrinthine fistula. Reviewed

    Michihiko Sone, Terukazu Mizuno, Makoto Sugiura, Shinji Naganawa, Tsutomu Nakashima

    Otol Neurotol   Vol. 28   page: 1029-1033   2007

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  15. Improved 3D-real Inversion Recovery: A Robust Imaging Technique for Endolymphatic Hydrops after Intravenous Administration of Gadolinium

    Naganawa Shinji, Kawai Hisashi, Taoka Toshiaki, Sone Michihiko

    MAGNETIC RESONANCE IN MEDICAL SCIENCES   Vol. 18 ( 1 ) page: 105 - 108   2019

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.2463/mrms.bc.2017-0158

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  16. Prediction of gastroesophageal reflux in otitis media with effusion in adults Reviewed

    Michihiko Sone, Yuri Yamamuro, Hideo Hayashi, Eriko Yanagi, Yasumasa Niwa, Tsutomu Nakashima

    Acta Otolaryngol   Vol. 127   page: 470-473   2007

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  17. Fracture probability assessed using FRAX (R) in elderly women with benign paroxysmal positional vertigo

    Nakada Takafumi, Teranishi Masaaki, Ueda Yukio, Sone Michihiko

    AURIS NASUS LARYNX   Vol. 45 ( 6 ) page: 1173 - 1177   2018.12

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.anl.2018.05.002

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  18. Pitfalls of Using T2-contrast Enhancement Techniques in 3D-FLAIR to Detect Endolymphatic Hydrops.

    Kato Y, Naganawa S, Taoka T, Yoshida T, Sone M

    Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine     2022.5

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    DOI: 10.2463/mrms.mp.2022-0017

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  19. Safety and Clinical Benefits of Laryngeal Closure in Patients with Amyotrophic Lateral Sclerosis

    Yokoi Sayaka, Nishio Naoki, Maruo Takashi, Hiramatsu Mariko, Mukoyama Nobuaki, Tsuzuki Hidenori, Wada Akihisa, Atsuta Naoki, Ito Daisuke, Tsuboi Takashi, Sobue Gen, Katsuno Masahisa, Fujimoto Yasushi, Sone Michihiko

    DYSPHAGIA     2022.5

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  20. Letter to editor on the article "A non-invasive, automated diagnosis of Meniere's disease using radiomics and machine learning on conventional magnetic resonance imaging: a multicentric, case-controlled feasibility study" by van der Lubbe Mfja et al.

    Naganawa Shinji, Ito Rintaro, Taoka Toshiaki, Yoshida Tadao, Sone Michihiko

    RADIOLOGIA MEDICA   Vol. 127 ( 4 ) page: 458 - 459   2022.4

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  21. Polysomnographic characteristics and predictors of positional obstructive sleep apnea in Japanese elderly

    Miyata Seiko, Otake Hironao, Fujishiro Hiroshige, Iwamoto Kunihiro, Noda Akiko, Sone Michihiko, Ozaki Norio

    SLEEP AND BIOLOGICAL RHYTHMS     2022.3

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  22. Management of bilateral locally advanced squamous cell carcinoma of the external auditory canal

    Nishio Naoki, Okazaki Yuriko, Wada Akihisa, Tsuzuki Hidenori, Kambe Miki, Fujimoto Yasushi, Sone Michihiko

    ACTA OTO-LARYNGOLOGICA CASE REPORTS   Vol. 7 ( 1 ) page: 8 - 13   2022.2

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  23. Oncolytic HSV HF10 (canerpaturev, C-REV) promotes accumulation of CD8+PD-1-tumor-infiltrating T cells in a SCC model

    Mohamed Abdelmoneim A., Eissa Ibrahim R., Mukoyama Nobuaki, Abdelmoneim Mohamed, Naoe Yoshinori, Matsumura Shigeru, Bustosvillalobos Itzel, Ichinose Toru, Miyajima Noriyuki, Morimoto Daishi, Tanaka Maki, Fujimoto Yasushi, Sone Michihiko, Kodera Yasuhiro, Kasuya Hideki

    CANCER SCIENCE   Vol. 113   page: 526 - 526   2022.2

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    Language:Japanese  

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  24. Labyrinthine calcification in ears with otitis media and antineutrophil cytoplasmic antibody-associated vasculitis (OMAAV): A report of two cases.

    Yoshida T, Kobayashi M, Sugimoto S, Naganawa S, Sone M

    Auris, nasus, larynx     2022.1

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    DOI: 10.1016/j.anl.2022.01.004

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  25. Aging Brain and Hearing: A Mini-Review

    Uchida Yasue, Nishita Yukiko, Otsuka Rei, Sugiura Saiko, Sone Michihiko, Yamasoba Tatsuya, Kato Takashi, Iwata Kaori, Nakamura Akinori

    FRONTIERS IN AGING NEUROSCIENCE   Vol. 13   page: 791604   2022.1

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  26. Labyrinthitis With Endolymphatic Hydrops Revealed by Imaging Analysis in a Case With Severe Postoperative Complications Following Stapes Surgery

    Kobayashi Masumi, Yoshida Tadao, Uchida Yasue, Sugimoto Satofumi, Naganawa Shinji, Sone Michihiko

    OTOLOGY & NEUROTOLOGY   Vol. 43 ( 1 ) page: E134 - E136   2022.1

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  27. Parasagittal Cystic Lesions May Arise from the Pial Sheath around the Cortical Venous Wall.

    Naganawa S, Ito R, Taoka T, Yoshida T, Sone M

    Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine     2021.12

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    Language:English  

    DOI: 10.2463/mrms.bc.2021-0141

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  28. Relationship between Time-dependent Signal Changes in Parasagittal Perivenous Cysts and Leakage of Gadolinium-based Contrast Agents into the Subarachnoid Space.

    Naganawa S, Ito R, Nakamichi R, Kawamura M, Taoka T, Yoshida T, Sone M

    Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine   Vol. 20 ( 4 ) page: 378 - 384   2021.12

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    DOI: 10.2463/mrms.mp.2020-0138

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  29. Increased risk of thyroid dysfunction by PD-1 and CTLA-4 blockade in patients without thyroid autoantibodies at baseline.

    Iwama S, Kobayashi T, Yasuda Y, Okuji T, Ito M, Ando M, Zhou X, Yamagami A, Onoue T, Kawaguchi Y, Miyata T, Sugiyama M, Takagi H, Hagiwara D, Suga H, Banno R, Hase T, Morise M, Wakahara K, Yokota K, Kato M, Nishio N, Tanaka C, Miyata K, Ogura A, Ito T, Sawada T, Shimokata T, Niimi K, Ohka F, Ishigami M, Gotoh M, Hashimoto N, Saito R, Kiyoi H, Kajiyama H, Ando Y, Hibi H, Sone M, Akiyama M, Kodera Y, Arima H

    The Journal of clinical endocrinology and metabolism     2021.11

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    DOI: 10.1210/clinem/dgab829

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  30. Peripheral Retinal Leakage after Intravenous Administration of a Gadolinium-based Contrast Agent: Age Dependence, Temporal and Inferior Predominance and Potential Implications for Eye Homeostasis.

    Naganawa S, Ito R, Kawamura M, Taoka T, Yoshida T, Sone M

    Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine     2021.10

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    DOI: 10.2463/mrms.mp.2021-0100

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  31. Magnetic resonance cisternography imaging findings related to the leakage of Gadolinium into the subarachnoid space

    Nakamichi Rei, Taoka Toshiaki, Kawai Hisashi, Yoshida Tadao, Sone Michihiko, Naganawa Shinji

    JAPANESE JOURNAL OF RADIOLOGY   Vol. 39 ( 10 ) page: 927 - 937   2021.10

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  32. Clinical course of liver injury induced by immune checkpoint inhibitors in patients with advanced malignancies

    Ito Takanori, Ishigami Masatoshi, Yamamoto Takafumi, Mizuno Kazuyuki, Yamamoto Kenta, Imai Norihiro, Ishizu Yoji, Honda Takashi, Kawashima Hiroki, Yasuda Satoshi, Toyoda Hidenori, Yokota Kenji, Hase Tetsunari, Nishio Naoki, Maeda Osamu, Kato Masashi, Hashimoto Naozumi, Hibi Hideharu, Kodera Yasuhiro, Sone Michihiko, Ando Yuichi, Akiyama Masashi, Shimoyama Yoshie, Fujishiro Mitsuhiro

    HEPATOLOGY INTERNATIONAL   Vol. 15 ( 5 ) page: 1278 - 1287   2021.10

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  33. Facial nerve palsy associated with chronic recurrent multifocal osteomyelitis

    Yang Cheng-Jui, Yoshida Tadao, Sugimoto Satofumi, Teranishi Masaaki, Sone Michihiko

    PEDIATRICS INTERNATIONAL   Vol. 63 ( 9 ) page: 1125 - 1127   2021.9

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  34. Dietary habits and medical examination findings in Japanese adults middle-aged or older who live alone

    Nakashima Tsutomu, Katayama Naomi, Saji Naoki, Teranishi Masaaki, Yoshida Tadao, Suzuki Hirokazu, Sone Michihiko, Hamajima Nobuyuki

    NUTRITION   Vol. 89   page: 111268   2021.9

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  35. Evaluation of the blood-perilymph barrier in ears with endolymphatic hydrops

    Yoshida Tadao, Kobayashi Masumi, Sugimoto Satofumi, Teranishi Masaaki, Naganawa Shinji, Sone Michihiko

    ACTA OTO-LARYNGOLOGICA   Vol. 141 ( 8 ) page: 736 - 741   2021.8

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  36. Oncolytic herpes simplex virus HF10 (canerpaturev) promotes accumulation of CD8(+)PD-1(-) tumor-infiltrating T cells in PD-L1-enriched tumor microenvironment

    Eissa Ibrahim Ragab, Mukoyama Nobuaki, Abdelmoneim Mohamed, Naoe Yoshinori, Matsumura Shigeru, Bustos-Villalobos Itzel, Ichinose Toru, Miyajima Noriyuki, Morimoto Daishi, Tanaka Maki, Fujimoto Yasushi, Sone Michihiko, Kodera Yasuhiro, Kasuya Hideki

    INTERNATIONAL JOURNAL OF CANCER   Vol. 149 ( 1 ) page: 214 - 227   2021.7

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  37. Dilatation of the Endolymphatic Space in the Ampulla of the Posterior Semicircular Canal: A New Clinical Finding Detected on Magnetic Resonance Imaging

    Morioka Masaru, Sugimoto Satofumi, Yoshida Tadao, Teranishi Masaaki, Kobayashi Masumi, Nishio Naoki, Katayama Naomi, Naganawa Shinji, Sone Michihiko

    OTOLOGY & NEUROTOLOGY   Vol. 42 ( 6 ) page: E643 - E647   2021.7

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  38. Surgical Classification of Radical Temporal Bone Resection and Transcranial Tympanotomy: A Retrospective Study from the Neurosurgical Perspective

    Iwami Kenichiro, Fujii Masazumi, Nishio Naoki, Maruo Takashi, Yoshida Tadao, Mukoyama Nobuaki, Osuka Koji, Takanari Keisuke, Murotani Kenta, Kamei Yuzuru, Sone Michihiko, Fujimoto Yasushi, Saito Kiyoshi

    WORLD NEUROSURGERY   Vol. 151   page: E192 - E207   2021.7

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  39. Relationship between cognitive impairment and olfactory function among older adults with olfactory impairment Saiko Sugiura a , e , Michihiko Sone b

    Suzuki Hirokazu, Teranishi Masaaki, Katayama Naomi, Nakashima Tsutomu, Sugiura Saiko, Sone Michihiko

    AURIS NASUS LARYNX   Vol. 48 ( 3 ) page: 420 - 427   2021.6

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  40. Treatment outcome and pattern of recurrence of sinonasal squamous cell carcinoma with EGFR-mutation and human papillomavirus

    Nishikawa Daisuke, Sasaki Eiichi, Suzuki Hidenori, Beppu Shintaro, Sawabe Michi, Terada Hoshino, Sone Michihiko, Hanai Nobuhiro

    JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY   Vol. 49 ( 6 ) page: 494 - 500   2021.6

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  41. Surgical strategy and optimal timing of tracheostomy in patients with COVID-19: Early experiences in Japan

    Nishio Naoki, Hiramatsu Mariko, Goto Yukari, Shindo Yuichiro, Yamamoto Takanori, Jingushi Naruhiro, Wakahara Keiko, Sone Michihiko

    AURIS NASUS LARYNX   Vol. 48 ( 3 ) page: 518 - 524   2021.6

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  42. Cross-sectional Area of the Superior Petrosal Sinus is Reduced in Patients with Significant Endolymphatic Hydrops.

    Naganawa S, Ito R, Kawai H, Kawamura M, Taoka T, Yoshida T, Sone M

    Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine     2021.4

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    Language:English  

    DOI: 10.2463/mrms.mp.2021-0010

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  43. MR Imaging of Endolymphatic Hydrops in Five Minutes.

    Naganawa S, Ito R, Kawai H, Kawamura M, Taoka T, Sakai M, Ichikawa K, Yoshida T, Sone M

    Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine     2021.4

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    DOI: 10.2463/mrms.ici.2021-0022

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  44. Cochlear implantation in patient with Charcot-Marie-Tooth disease

    Kobayashi Masumi, Yoshida Tadao, Sugimoto Satofumi, Teranishi Masaaki, Hara Daisuke, Kimata Yukari, Sone Michihiko

    AURIS NASUS LARYNX   Vol. 48 ( 2 ) page: 327 - 330   2021.4

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  45. Safety and feasibility of fat injection therapy with adipose-derived stem cells in a rabbit hypoglossal nerve paralysis model: A pilot study

    Wada Akihisa, Nishio Naoki, Yokoi Sayaka, Tsuzuki Hidenori, Mukoyama Nobuaki, Maruo Takashi, Hiramatsu Mariko, Yamamoto Tokunori, Goto Momokazu, Fujimoto Yasushi, Sone Michihiko

    AURIS NASUS LARYNX   Vol. 48 ( 2 ) page: 274 - 280   2021.4

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  46. Feasibility of virtual surgical simulation in the head and neck region for soft tissue reconstruction using free flap: a comparison of preoperative and postoperative volume measurement

    Yokoi S., Nishio N., Fujimoto Y., Fujii M., Iwami K., Hayashi Y., Takanari K., Hiramatsu M., Maruo T., Mukoyama N., Tsuzuki H., Wada A., Kamei Y., Sone M.

    INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY   Vol. 50 ( 3 ) page: 316 - 322   2021.3

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  47. Imaging of endolymphatic hydrops on a vertigo attack of Meniere's disease

    Nakada Takafumi, Teranishi Masaaki, Sugiura Saiko, Uchida Yasue, Naganawa Shinji, Sone Michihiko

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 83 ( 1 ) page: 209 - 216   2021.2

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  48. Lesion-specific prognosis by magnetic resonance imaging in sudden sensorineural hearing loss

    Yang Cheng-Jui, Yoshida Tadao, Sugimoto Satofumi, Teranishi Masaaki, Kobayashi Masumi, Nishio Naoki, Naganawa Shinji, Sone Michihiko

    ACTA OTO-LARYNGOLOGICA   Vol. 141 ( 1 ) page: 5 - 9   2021.1

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  49. Eosinophil prognostic scores for patients with head and neck squamous cell carcinoma treated with nivolumab

    Nishikawa Daisuke, Suzuki Hidenori, Beppu Shintaro, Terada Hoshino, Sawabe Michi, Kadowaki Shigenori, Sone Michihiko, Hanai Nobuhiro

    CANCER SCIENCE   Vol. 112 ( 1 ) page: 339 - 346   2021.1

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  50. Relationship between Parasagittal Perivenous Cysts and Leakage of Gadolinium-based Contrast Agents into the Subarachnoid Space around the Cortical Veins after Intravenous Administration

    Naganawa Shinji, Ito Rintaro, Nakamichi Rei, Kawamura Mariko, Kawai Hisashi, Taoka Toshiaki, Yoshida Tadao, Sone Michihiko

    MAGNETIC RESONANCE IN MEDICAL SCIENCES   Vol. 20 ( 3 ) page: 245 - 252   2021

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  51. MR Imaging of Endolymphatic Hydrops: Utility of iHYDROPS-Mi2 Combined with Deep Learning Reconstruction Denoising

    Naganawa Shinji, Nakamichi Rei, Ichikawa Kazushige, Kawamura Mariko, Kawai Hisashi, Yoshida Tadao, Sone Michihiko

    MAGNETIC RESONANCE IN MEDICAL SCIENCES   Vol. 20 ( 3 ) page: 272 - 279   2021

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  52. Intracranial Distribution of Intravenously Administered Gadolinium-based Contrast Agent over a Period of 24 Hours: Evaluation with 3D-real IR Imaging and MR Fingerprinting

    Naganawa Shinji, Ito Rintaro, Kato Yutaka, Kawai Hisashi, Taoka Toshiaki, Yoshida Tadao, Maruyama Katsuya, Murata Katsutoshi, Koerzdoerfer Gregor, Pfeuffer Josef, Nittka Mathias, Sone Michihiko

    MAGNETIC RESONANCE IN MEDICAL SCIENCES   Vol. 20 ( 1 ) page: 91 - 98   2021

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  53. Significance of high signal intensity in the endolymphatic duct on magnetic resonance imaging in ears with otological disorders

    Morimoto Kyoko, Yoshida Tadao, Kobayashi Masumi, Sugimoto Satofumi, Nishio Naoki, Teranishi Masaaki, Naganawa Shinji, Sone Michihiko

    ACTA OTO-LARYNGOLOGICA   Vol. 140 ( 10 ) page: 818 - 822   2020.10

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  54. Prospective Evaluation of Health-Related Quality of Life in Patients Undergoing Anterolateral Craniofacial Resection with Orbital Exenteration

    Mukoyama Nobuaki, Nishio Naoki, Kimura Hiroyuki, Kishi Shinichi, Tokura Tatsuya, Kimura Hiroki, Hiramatsu Mariko, Maruo Takashi, Tsuzuki Hidenori, Fujii Masazumi, Iwami Kenichiro, Takanari Keisuke, Kamei Yuzuru, Ozaki Norio, Sone Michihiko, Fujimoto Yasushi

    JOURNAL OF NEUROLOGICAL SURGERY PART B-SKULL BASE   Vol. 81 ( 05 ) page: 585 - 593   2020.10

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  55. Effects of endolymphatic hydrops on acoustic energy absorbance

    Kobayashi Masumi, Yoshida Tadao, Sugimoto Satofumi, Shimono Mariko, Teranishi Masaaki, Naganawa Shinji, Sone Michihiko

    ACTA OTO-LARYNGOLOGICA   Vol. 140 ( 8 ) page: 626 - 631   2020.7

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  56. Patient characteristics affecting accurate detection of sleep apnea using a bed sheet-type portable monitor

    Miyata Seiko, Otake Hironao, Ando Motoo, Okuda Masato, Fujishiro Hiroshige, Iwamoto Kunihiro, Noda Akiko, Sone Michihiko, Ozaki Norio

    SLEEP AND BREATHING   Vol. 24 ( 2 ) page: 783 - 790   2020.6

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s11325-019-01963-8

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  57. Anesthetic and surgical management of tracheostomy in a patient with COVID-19

    Hiramatsu Mariko, Nishio Naoki, Ozaki Masayuki, Shindo Yuichiro, Suzuki Katsunao, Yamamoto Takanori, Fujimoto Yasushi, Sone Michihiko

    AURIS NASUS LARYNX   Vol. 47 ( 3 ) page: 472 - 476   2020.6

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  58. Real world data of liver injury induced by immune checkpoint inhibitors in Japanese patients with advanced malignancies

    Mizuno Kazuyuki, Ito Takanori, Ishigami Masatoshi, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Kawashima Hiroki, Inukai Yosuke, Toyoda Hidenori, Yokota Kenji, Hase Tetsunari, Maeda Osamu, Kiyoi Hitoshi, Nagino Masato, Hibi Hideharu, Kodera Yasuhiro, Fujimoto Yasushi, Sone Michihiko, Gotoh Momokazu, Ando Yuichi, Akiyama Masashi, Hasegawa Yoshinori, Fujishiro Mitsuhiro

    JOURNAL OF GASTROENTEROLOGY   Vol. 55 ( 6 ) page: 653 - 661   2020.6

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  59. Anti-thyroid antibodies and thyroid echo pattern at baseline as risk factors for thyroid dysfunction induced by anti-programmed cell death-1 antibodies: a prospective study.

    Okada N, Iwama S, Okuji T, Kobayashi T, Yasuda Y, Wada E, Onoue T, Goto M, Sugiyama M, Tsunekawa T, Takagi H, Hagiwara D, Ito Y, Suga H, Banno R, Hase T, Morise M, Kanda M, Yokota K, Hashimoto N, Ando M, Fujimoto Y, Nagino M, Kodera Y, Fujishiro M, Hibi H, Sone M, Kiyoi H, Gotoh M, Ando Y, Akiyama M, Hasegawa Y, Arima H

    British journal of cancer   Vol. 122 ( 6 ) page: 771 - 777   2020.3

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    DOI: 10.1038/s41416-020-0736-7

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  60. The Space between the Pial Sheath and the Cortical Venous Wall May Connect to the Meningeal Lymphatics.

    Naganawa S, Ito R, Taoka T, Yoshida T, Sone M

    Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine   Vol. 19 ( 1 ) page: 1 - 4   2020

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.2463/mrms.bc.2019-0099

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  61. Confirmation of Age-dependence in the Leakage of Contrast Medium around the Cortical Veins into Cerebrospinal Fluid after Intravenous Administration of Gadolinium-based Contrast Agent.

    Naganawa S, Ito R, Kawai H, Taoka T, Yoshida T, Sone M

    Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine   Vol. 19 ( 4 ) page: 375 - 381   2020

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    DOI: 10.2463/mrms.mp.2019-0182

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  62. Bronchial wall thickening is associated with severity of chronic rhinosinusitis

    Majima Suguru, Wakahara Keiko, Nishio Tomoko, Nishio Naoki, Teranishi Masaaki, Iwano Shingo, Hirakawa Akihiro, Hashimoto Naozumi, Sone Michihiko, Hasegawa Yoshinori

    RESPIRATORY MEDICINE   Vol. 170   page: 106024   2020

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  63. Pituitary dysfunction induced by immune checkpoint inhibitors is associated with better overall survival in both malignant melanoma and non-small cell lung carcinoma: a prospective study

    Kobayashi Tomoko, Iwama Shintaro, Yasuda Yoshinori, Okada Norio, Okuji Takayuki, Ito Masaaki, Onoue Takeshi, Goto Motomitsu, Sugiyama Mariko, Tsunekawa Taku, Takagi Hiroshi, Hagiwara Daisuke, Ito Yoshihiro, Suga Hidetaka, Banno Ryoichi, Yokota Kenji, Hase Tetsunari, Morise Masahiro, Hashimoto Naozumi, Ando Masahiko, Fujimoto Yasushi, Hibi Hideharu, Sone Michihiko, Ando Yuichi, Akiyama Masashi, Hasegawa Yoshinori, Arima Hiroshi

    JOURNAL FOR IMMUNOTHERAPY OF CANCER   Vol. 8 ( 2 )   2020

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  64. Diagnosis of cervical lymph node metastases in head and neck cancer with ultrasonic measurement of lymph node volume

    Nishio Naoki, Fujimoto Yasushi, Hiramatsu Mariko, Maruo Takashi, Tsuzuki Hidenori, Mukoyama Nobuaki, Yokoi Sayaka, Wada Akihisa, Furukawa Madoka Kaneko, Furukawa Masaki, Sone Michihiko

    AURIS NASUS LARYNX   Vol. 46 ( 6 ) page: 889 - 895   2019.12

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    DOI: 10.1016/j.anl.2019.02.003

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  65. Mixed cell type in airway inflammation is the dominant phenotype in asthma patients with severe chronic rhinosinusitis

    Nishio Tomoko, Wakahara Keiko, Suzuki Yoshihiro, Nishio Naoki, Majima Suguru, Nakamura Saya, Teranishi Masaaki, Nakatochi Masahiro, Sone Michihiko, Hasegawa Yoshinori

    ALLERGOLOGY INTERNATIONAL   Vol. 68 ( 4 ) page: 515 - 520   2019.10

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    DOI: 10.1016/j.alit.2019.05.004

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  66. Clinical Features of Ears With Otosclerosis and Endolymphatic Hydrops

    Wang Fei, Yoshida Tadao, Sugimoto Satofumi, Shimono Mariko, Teranishi Masaaki, Naganawa Shinji, Sone Michihiko

    OTOLOGY & NEUROTOLOGY   Vol. 40 ( 4 ) page: 441 - 445   2019.4

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    DOI: 10.1097/MAO.0000000000002175

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  67. Significance of Endolymphatic Hydrops Herniation Into the Semicircular Canals Detected on MRI.

    Sugimoto S, Yoshida T, Teranishi M, Kobayashi M, Shimono M, Naganawa S, Sone M

    Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology   Vol. 39 ( 10 ) page: 1229 - 1234   2018.12

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    DOI: 10.1097/MAO.0000000000002022

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  68. Prognostic Markers in Head and Neck Cancer Patients Treated with Nivolumab

    Nishikawa Daisuke, Suzuki Hidenori, Koide Yusuke, Beppu Shintaro, Kadowaki Shigenori, Sone Michihiko, Hanai Nobuhiro

    CANCERS   Vol. 10 ( 12 )   2018.12

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    DOI: 10.3390/cancers10120466

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  69. Smaller Hippocampal Volume and Degraded Peripheral Hearing Among Japanese Community Dwellers

    Uchida Yasue, Nishita Yukiko, Kato Takashi, Iwata Kaori, Sugiura Saiko, Suzuki Hirokazu, Sone Michihiko, Tange Chikako, Otsuka Rei, Ando Fujiko, Shimokata Hiroshi, Nakamura Akinori

    FRONTIERS IN AGING NEUROSCIENCE   Vol. 10   page: 319   2018.10

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    DOI: 10.3389/fnagi.2018.00319

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  70. Association between Uncoupling Protein 2 Gene Ala55val Polymorphism and Sudden Sensorineural Hearing Loss

    Koide Yusuke, Teranishi Masaaki, Sugiura Saiko, Uchida Yasue, Nishio Naoki, Kato Ken, Otake Hironao, Yoshida Tadao, Otsuka Rei, Ando Fujiko, Shimokata Hiroshi, Hasegawa Yasuhisa, Nakashima Tsutomu, Sone Michihiko

    JOURNAL OF INTERNATIONAL ADVANCED OTOLOGY   Vol. 14 ( 2 ) page: 166 - 169   2018.8

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    DOI: 10.5152/iao.2018.5442

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  71. Pathological tumor volume predicts survival outcomes in oral squamous cell carcinoma

    Mukoyama Nobuaki, Suzuki Hidenori, Hanai Nobuhiro, Sone Michihiko, Hasegawa Yasuhisa

    ONCOLOGY LETTERS   Vol. 16 ( 2 ) page: 2471 - 2477   2018.8

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    DOI: 10.3892/ol.2018.8951

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  72. The Relationship Between Endolymphatic Hydrops in the Vestibule and Low-Frequency Air-Bone Gaps

    Sugimoto Satofumi, Yoshida Tadao, Teranishi Masaaki, Okazaki Yuriko, Naganawa Shinji, Sone Michihiko

    LARYNGOSCOPE   Vol. 128 ( 7 ) page: 1658 - 1662   2018.7

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    DOI: 10.1002/lary.26898

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  73. The HECT-type ubiquitin ligase Tom1 contributes to the turnover of Spo12, a component of the FEAR network, in G2/M phase

    Nakatsukasa Kunio, Sone Megumi, Alemayehu Dawit Hailu, Okumura Fumihiko, Kamura Takumi

    FEBS LETTERS   Vol. 592 ( 10 ) page: 1716-1724   2018.5

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    DOI: 10.1002/1873-3468.13066

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  74. Imaging of the endolymphatic space in patients with Meniere's disease

    Yoshida Tadao, Sugimoto Satofumi, Teranishi Masaaki, Otake Hironao, Yamazaki Masahiro, Naganawa Shinji, Nakashima Tsutomu, Sone Michihiko

    AURIS NASUS LARYNX   Vol. 45 ( 1 ) page: 33 - 38   2018.2

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    DOI: 10.1016/j.anl.2017.02.002

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  75. Maxillary sinus carcinoma outcomes over 60 years: experience at a single institution

    Nishio Naoki, Fujimoto Yasushi, Hiramatsu Mariko, Maruo Takashi, Tsuzuki Hidenori, Mukoyama Nobuaki, Shimono Mariko, Sone Michihiko, Kawabe Yoshitaka, Saito Kiyoshi, Fujii Masazumi, Nakashima Tsutomu

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 80 ( 1 ) page: 91 - 98   2018.2

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    DOI: 10.18999/nagjms.80.1.91

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  76. Sonographic detection of a lingual node metastasis from early squamous cell cancer of the tongue

    Nishio Naoki, Fujimoto Yasushi, Hiramatsu Mariko, Yamamoto Yoko, Sone Michihiko

    JOURNAL OF CLINICAL ULTRASOUND   Vol. 46 ( 1 ) page: 69 - 72   2018.1

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    DOI: 10.1002/jcu.22486

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  77. Prevalence and Risk Factors of MRI Abnormality Which Was Suspected as Sinusitis in Japanese Middle-Aged and Elderly Community Dwellers

    Sugiura Saiko, Yasue Minori, Uchida Yasue, Teranishi Masaaki, Sone Michihiko, Suzuki Hirokazu, Nakashima Tsutomu, Otsuka Rei, Ando Fujiko, Shimokata Hiroshi

    BIOMED RESEARCH INTERNATIONAL   Vol. 2018   page: 4096845   2018

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    DOI: 10.1155/2018/4096845

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  78. Computed Tomographic Assessment of Autologous Fat Injection Augmentation for Vocal Fold Paralysis

    Nishio Naoki, Fujimoto Yasushi, Hiramatsu Mariko, Maruo Takashi, Suga Kenji, Tsuzuki Hidenori, Mukoyama Nobuaki, Shimono Mariko, Toriyama Kazuhiro, Takanari Keisuke, Kamei Yuzuru, Sone Michihiko

    LARYNGOSCOPE INVESTIGATIVE OTOLARYNGOLOGY   Vol. 2 ( 6 ) page: 459 - 465   2017.12

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    DOI: 10.1002/lio2.125

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  79. Significance of Endolymphatic Hydrops in Ears With Unilateral Sensorineural Hearing Loss

    Okazaki Yuriko, Yoshida Tadao, Sugimoto Satofumi, Teranishi Masaaki, Kato Ken, Naganawa Shinji, Sone Michihiko

    OTOLOGY & NEUROTOLOGY   Vol. 38 ( 8 ) page: 1076 - 1080   2017.9

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    DOI: 10.1097/MAO.0000000000001499

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  80. The comparison of nasal surgery and CPAP on daytime sleepiness in patients with OSAS

    Tagaya Mitsuhiko, Otake Hironao, Suzuki Keisuke, Yasuma Fumihiko, Yamamoto Hiroshi, Noda Akiko, Nishimura Yoichi, Sone Michihiko, Nakashima Tsutomu, Nakata Seiichi

    RHINOLOGY   Vol. 55 ( 3 ) page: 269-273   2017.9

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    DOI: 10.4193/Rhino17.026

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  81. Letter to Editors: Detection of endolymphatic hydrops using traditional MR imaging sequences.

    Naganawa S, Sone M

    American journal of otolaryngology   Vol. 38 ( 5 ) page: 637-638   2017.9

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    DOI: 10.1016/j.amjoto.2017.06.014

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  82. FDG-PET/CT predicts survival and lung metastasis of hypopharyngeal cancer in a multi-institutional retrospective study

    Suzuki Hidenori, Kato Katsuhiko, Nishio Masami, Tamaki Tsuneo, Fujimoto Yasushi, Hiramatsu Mariko, Hanai Nobuhiro, Kodaira Takeshi, Itoh Yoshiyuki, Naganawa Shinji, Sone Michihiko, Hasegawa Yasuhisa

    ANNALS OF NUCLEAR MEDICINE   Vol. 31 ( 7 ) page: 514 - 520   2017.8

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    DOI: 10.1007/s12149-017-1176-1

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  83. Magnetic resonance imaging evaluation of endolymphatic hydrops and post-operative findings in cases with otosclerosis Reviewed

    Sone M, Yoshida T, Sugimoto S, Morimoto K, Okazaki Y, Teranishi M, Naganawa S, Nakashima T

    Acta Otolaryngol   Vol. 1373 ( 3 ) page: 242-245   2017.3

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  84. Magnetic resonance imaging evaluation of endolymphatic hydrops andpost-operative findings in cases with otosclerosis

    Sone Michihiko, Yoshida Tadao, Sugimoto Satofumi, Morimoto Kyoko, Okazaki Yuriko, Teranishi Masaaki, Naganawa Shinji, Nakashima Tsutomu

    ACTA OTO-LARYNGOLOGICA   Vol. 137 ( 3 ) page: 242 - 245   2017.3

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    DOI: 10.1080/00016489.2016.1232862

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  85. Atrial natriuretic peptide-conjugated chitosan-hydrazone-mPEG copolymer nanoparticles as pH-responsive carriers for intracellular delivery of prednisone.

    M GA, C SK, Henry LJK, Natesan S, Kandasamy R

    Carbohydrate polymers   Vol. 157   page: 1677-1686   2017.2

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    DOI: 10.1016/j.carbpol.2016.11.049

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  86. Inner ear disturbances related to middle ear inflammation

    Sone Michihiko

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 79 ( 1 ) page: 1 - 7   2017.2

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    DOI: 10.18999/nagjms.79.1.1

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  87. Endolymphatic hydrops in patients with unilateral and bilateral Meniere's disease

    Morimoto Kyoko, Yoshida Tadao, Sugiura Saiko, Kato Masahiro, Kato Ken, Teranishi Masaaki, Naganawa Shinji, Nakashima Tsutomu, Sone Michihiko

    ACTA OTO-LARYNGOLOGICA   Vol. 137 ( 1 ) page: 23 - 28   2017.1

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    DOI: 10.1080/00016489.2016.1217042

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  88. Magnetic resonance imaging evaluation of endolymphatic hydrops and post-operative findings in cases with otosclerosis. Reviewed

    Sone M, Yoshida T, Sugimoto S, Morimoto K, Okazaki Y, Teranishi M, Naganawa S, Nakashima T.

    Acta Otolaryngol   Vol. 137 ( 3 ) page: 242-245   2017

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  89. AFRS caused by S. commune diagnosed using specific antibodies and genetic identification

    Nakada T., Teranishi M., Tomital M., Ueda Y., Kamei K., Sone M.

    B-ENT   Vol. 13 ( 2 ) page: 123-127   2017

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  90. The effect of initial treatment on hearing prognosis in idiopathic sudden sensorineural hearing loss: a nationwide survey in Japan

    Okada Masahiro, Hato Naohito, Nishio Shin-ya, Kitoh Ryosuke, Ogawa Kaoru, Kanzaki Sho, Sone Michihiko, Fukuda Satoshi, Hara Akira, Ikezono Tetsuo, Ishikawa Kotaro, Iwasaki Satoshi, Kaga Kimitaka, Kakehata Seiji, Matsubara Atsushi, Matsunaga Tatsuo, Murata Takaaki, Naito Yasushi, Nakagawa Takashi, Nishizaki Kazunori, Noguchi Yoshihiro, Sano Hajime, Sato Hiroaki, Suzuki Mikio, Shojaku Hideo, Takahashi Haruo, Takeda Hidehiko, Tono Tetsuya, Yamashita Hiroshi, Yamasoba Tatsuya, Usami Shin-ichi

    ACTA OTO-LARYNGOLOGICA   Vol. 137 ( sup565 ) page: S30 - S33   2017

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    DOI: 10.1080/00016489.2017.1296970

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  91. Nationwide epidemiological survey of idiopathic sudden sensorineural hearing loss in Japan

    Kitoh Ryosuke, Nishio Shin-ya, Ogawa Kaoru, Kanzaki Sho, Hato Naohito, Sone Michihiko, Fukuda Satoshi, Hara Akira, Ikezono Tetsuo, Ishikawa Kotaro, Iwasaki Satoshi, Kaga Kimitaka, Kakehata Seiji, Matsubara Atsushi, Matsunaga Tatsuo, Murata Takaaki, Naito Yasushi, Nakagawa Takashi, Nishizaki Kazunori, Noguchi Yoshihiro, Sano Hajime, Sato Hiroaki, Suzuki Mikio, Shojaku Hideo, Takahashi Haruo, Takeda Hidehiko, Tono Testuya, Yamashita Hiroshi, Yamasoba Tatsuya, Usami Shin-ichi

    ACTA OTO-LARYNGOLOGICA   Vol. 137 ( sup565 ) page: S8 - S16   2017

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    DOI: 10.1080/00016489.2017.1297537

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  92. Improved HYDROPS: Imaging of Endolymphatic Hydrops after Intravenous Administration of Gadolinium

    Naganawa Shinji, Kawai Hisashi, Taoka Toshiaki, Sone Michihiko

    MAGNETIC RESONANCE IN MEDICAL SCIENCES   Vol. 16 ( 4 ) page: 357 - 361   2017

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    DOI: 10.2463/mrms.tn.2016-0126

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  93. Idiopathic sudden sensorineural hearing loss and acute low-tone sensorineural hearing loss: a comparison of the results of a nationwide epidemiological survey in Japan

    Yoshida Tadao, Sone Michihiko, Kitoh Ryosuke, Nishio Shin-ya, Ogawa Kaoru, Kanzaki Sho, Hato Naohito, Fukuda Satoshi, Hara Akira, Ikezono Tetsuo, Ishikawa Kotaro, Iwasaki Satoshi, Kaga Kimitaka, Kakehata Seiji, Matsubara Atsushi, Matsunaga Tatsuo, Murata Takaaki, Naito Yasushi, Nakagawa Takashi, Nishizaki Kazunori, Noguchi Yoshihiro, Sano Hajime, Sato Hiroaki, Suzuki Mikio, Shojaku Hideo, Takahashi Haruo, Takeda Hidehiko, Tono Testuya, Yamashita Hiroshi, Yamasoba Tatsuya, Usami Shin-ichi

    ACTA OTO-LARYNGOLOGICA   Vol. 137 ( sup565 ) page: S38 - S43   2017

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    DOI: 10.1080/00016489.2017.1297539

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  94. The clinical features and prognosis of mumps-associated hearing loss: a retrospective, multi-institutional investigation in Japan

    Morita Shinya, Fujiwara Keishi, Fukuda Atsushi, Fukuda Satoshi, Nishio Shin-ya, Kitoh Ryosuke, Hato Naohito, Ikezono Tetsuo, Ishikawa Kotaro, Kaga Kimitaka, Matsubara Atsushi, Matsunaga Tatsuo, Murata Takaaki, Naito Yasushi, Nishizaki Kazunori, Ogawa Kaoru, Sano Hajime, Sato Hiroaki, Sone Michihiko, Suzuki Mikio, Takahashi Haruo, Tono Tetsuya, Yamashita Hiroshi, Yamasoba Tatsuya, Usami Shin-ichi

    ACTA OTO-LARYNGOLOGICA   Vol. 137 ( sup565 ) page: S44 - S47   2017

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    DOI: 10.1080/00016489.2017.1290826

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  95. Relationships among drinking and smoking habits, history of diseases, body mass index and idiopathic sudden sensorineural hearing loss in Japanese patients

    Umesawa Mitsumasa, Kobashi Gen, Kitoh Ryoshuke, Nishio Shin-ya, Ogawa Kaoru, Hato Naohito, Sone Michihiko, Fukuda Satoshi, Hara Akira, Ikezono Tetsuo, Ishikawa Kotaro, Iwasaki Satoshi, Kaga Kimitaka, Kakehata Seiji, Matsubara Atsushi, Matsunaga Tatsuo, Murata Takaaki, Naito Yasushi, Nakagawa Takashi, Nishizaki Kazunori, Noguchi Yoshihiro, Sano Hajime, Sato Hiroaki, Suzuki Mikio, Shojaku Hideo, Takahashi Haruo, Takeda Hidehiko, Tono Tetsuya, Yamashita Hiroshi, Yamasoba Tatsuya, Usami Shin-ichi

    ACTA OTO-LARYNGOLOGICA   Vol. 137 ( sup565 ) page: S17 - S23   2017

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    DOI: 10.1080/00016489.2017.1297898

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  96. Epidemiological survey of acute low-tone sensorineural hearing loss

    Sato Hiroaki, Kuwashima Shigeru, Nishio Shin-ya, Kitoh Ryosuke, Fukuda Satoshi, Hara Akira, Hato Naohito, Ikezono Tetsuo, Ishikawa Kotaro, Iwasaki Satoshi, Kaga Kimitaka, Matsubara Atsushi, Matsunaga Tatsuo, Murata Takaaki, Naito Yasushi, Nakagawa Takashi, Nishizaki Kazunori, Noguchi Yoshihiro, Ogawa Kaoru, Sano Hajime, Sone Michihiko, Shojaku Hideo, Takahashi Haruo, Tono Testuya, Yamashita Hiroshi, Yamasoba Tatsuya, Usami Shin-ichi

    ACTA OTO-LARYNGOLOGICA   Vol. 137 ( sup565 ) page: S34 - S37   2017

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    DOI: 10.1080/00016489.2017.1297538

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  97. Detection of endolymphatic hydrops using traditional MR imaging sequences

    Naganawa Shinji, Sone Michihiko

    AMERICAN JOURNAL OF OTOLARYNGOLOGY   Vol. 38 ( 5 ) page: 637-638   2017

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    Web of Science

  98. Magnetic resonance imaging evaluation of endolymphatic hydrops in cases with otosclerosis. Reviewed

    Mukaida T, Sone M, Yoshida T, Kato K, Teranishi M, Naganawa S, Nakashima T.

    Otol Neurotol   Vol. 36 ( 7 ) page: 1146-1150   2015

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  99. Numerical assessment of cholesteatoma by signal intensity on non-EP-DWI and ADC maps. Reviewed

    Suzuki H, Sone M, Yoshida T, Otake H, Kato K, TeranishiM, Suga K, Nakada T, Naganawa S, Nakashima T.

    Otol Neurotol   Vol. 35 ( 6 ) page: 1007-1010   2014

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  100. Evaluation of vascular activity in otosclerosis by laser-Doppler flowmetry: comparison with CT densitometry. Reviewed

    Sone M, Yoshida T, Otake H, Kato K, Teranishi M, Naganawa S, Nakashima T.

    Otol Neurotol   Vol. 34   page: 1559-1563   2013.12

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  101. Prevalence of laryngopharyngeal reflux symptoms: comparison between health check-up examinees and patients with otitis media. Reviewed

    Sone M, Katayama N, Kato T, Izawa K, Wada M, Hamajima N, Nakashima T

    Otolaryngol Head Neck Surg   Vol. 146 ( 4 ) page: 562-566   2012.4

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  102. Audiological signs in pediatric cases with dehiscence of the bony labyrinth caused by a high jugular bulb. Invited Reviewed

    Sone M, Katayama N, Naganawa S, Teranishi M, Nakashima T

    Int J Pedia Otorhinolaryngol   Vol. 76   page: 447-451   2012

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  103. Relevance and characteristics of gastroesophageal reflux in adult patients with otitis media with effusion Reviewed

    Sone M, Kato T, Suzuki Y, Arao H, Sugiyama K, Ishida K, Izawa K, Takasu A, Nakashima T.

    Auris Nasus Larynx   Vol. 38   page: 203-207   2011

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  104. Visualization of endolymphatic hydrops in patients with Meniere's disease Reviewed

    Tsutomu Nakashima, Shinji Naganawa, Makoto Sugiura, Masaaki Teranishi, Michihiko Sone, Hideo Hayashi, Seiichi Nakata, Naomi Katayama, Ieda Maria Ishida

    Laryngoscope   Vol. 17   page: 415-420   2007

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  105. *Vascular evaluation in laryngeal diseases: comparison between contact endoscopy and laser-Dopper flowmetry Reviewed

    Michihiko Sone, Eisuke Sato, Hideo Hayashi, Yasushi Fujimoto, Tsutomu Nakashima

    Arch Otolaryngol Head Neck Surg   Vol. 132   page: 1371-1374   2006

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Research Project for Joint Research, Competitive Funding, etc. 8

  1. 先天性および若年性の視覚聴覚二重障害の難病に対する医療および移行期医療支援に関する研究

    2021.4 - 2022.3

    厚生労働科学研究難治性疾患政策研究事業 

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    Authorship:Coinvestigator(s) 

  2. 先天性および若年性の視覚聴覚二重障害の原因となる難病の診療向上に向けた疾患横断的な全国多施設レジストリ研究

    2018.4 - 2021.3

    難治性疾患実用化研究事業 

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    Grant type:Competitive

  3. 高齢者における聴覚障害と総合機能・認知機能の包括的評価:難聴補正による認知症予防を目指した研究

    2018.4 - 2020.3

    長寿・障害総合研究事業 認知症研究開発事業 

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    Grant type:Competitive

  4. 難治性聴覚障害に関する調査研究

    2017.4 - 2022.3

    科学技術振興調整費 

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    Grant type:Competitive

  5. 難治性聴覚障害に関する調査研究

    2014.4 - 2017.3

    科学技術振興調整費 

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    Grant type:Competitive

  6. ステロイド依存性感音難聴の新しい診断法および診断基準に関する検討

    2010.4 - 2011.3

    科学技術振興調整費 

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    Grant type:Competitive

  7. 内外リンパ腔画像からみた内耳疾患の病態と局所療法

    2008.4 - 2010.3

    科学技術振興調整費 

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    Grant type:Competitive

  8. 人工内耳手術における内視鏡の開発

    2001.4 - 2004.3

    科学技術振興調整費 

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    Grant type:Competitive

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KAKENHI (Grants-in-Aid for Scientific Research) 11

  1. 内リンパ水腫疾患に対する新規治療法の開発

    Grant number:21K09605  2021.4 - 2024.3

    科学研究費助成事業  基盤研究(C)

    曽根 三千彦, 大神 信孝, 吉田 忠雄

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    Authorship:Principal investigator 

    Grant amount:\4290000 ( Direct Cost: \3300000 、 Indirect Cost:\990000 )

    メニエール病は、めまいや難聴などの症状を生じ生活の質を著しく低下させる疾患である。発作予防に対してさまざまな段階的治療法が推奨されているが、その有効性には限界がある。低侵襲で有効な治療法として、100 Hzの軽微な音刺激を連続して与えるという新たな治療法を提示し、症状や内耳機能改善効果を解析しその有効性を検証する。

  2. 人工内耳両側装用者における聴覚処理プロセスの解明

    Grant number:20K11183  2020.4 - 2023.3

    科学研究費助成事業  基盤研究(C)

    吉田 忠雄, 曽根 三千彦

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    Authorship:Coinvestigator(s) 

    成人の人工内耳両側装用は2017年に人工内耳適応基準が改定になったことを受け増加傾向にあるが、その実際の効果についてはまだ明らかとなっていない。人工内耳機器にも現状では健聴者の聴覚能と比較して限界があるのも事実である。
    本研究では、高度から重度の感音難聴患者が人工内耳を両側に装用することによって生じる潜在的効果および表情認識によって読話能力が評価可能であるかどうかについて検討を行う。両側装用のさらなる利点、欠点を明らかにすることで人工内耳の機器選択、プログラムの開発、リハビリテーションの技術向上に貢献すると考えられる。
    現代のマルチチャンネル人工内耳インプラントは、高度から重度の難聴者に対する介入成績が非常に良好であることが立証されている。静寂下におけるオープンセットでの語音聴取成績は良好であり、多くの患者に効果のあることがわかっている。過去30年間にわたって、人工内耳の技術が劇的に向上したことに加え、候補となる患者の基準が拡大してきており、人工内耳の安全性および有効性もより広く認められてきている。人工内耳を一側のみに装用している両側高度難聴者がほとんどであるが、過去20年の間に、人工内耳を両側に装用する患者数が増加してきている。聴神経系に両側から入力することには明らかな効果があり、これらの効果は音響心理学の分野で十分に立証されている。両側で聴くことの効果には、別々の複数音源からの語音聴取成績の向上、雑音下での聴取成績の向上、音源定位能力の向上、より満足度の高い「自然な」音の知覚などがあげられる。
    両側装用前の雑音下での語音聴取検査として1.一側のみ人工内耳装用、2.一側のみ補聴器装用、3.一側人工内耳、反対側に補聴器装用を行った。また、両側装用下において1.右のみ人工内耳装用、2.左のみ人工内耳装用、3.両側人工内耳装用の条件において測定を行った。2モーラの単語を用い、雑音下の語音了解度を検査する。検査は、適応型追跡アルゴリズム(2つ正解すると呈示レベルが下がる/1つ正解すると呈示レベルが上がる)を使用して実施し、精神測定機能で70.9%の正答率を追跡および推定する。これは、語音了解閾値(SRT)として知られている。音源定位では片側装用に比較し、両側装用による効果が非常に高いことが明らかとなった。一方で、方向性マスキング解除に関しては結果のばらつきが大きくさらに対象を増やして検討する必要があることが分かった。
    機器の整備も進んでおり、コロナ禍の影響も受けているが研究は滞りなく進んでいる。
    さらに研究対象者を増やし、検討を重ねる。コロナ禍においての症例のリクルートが課題であるが、感染対策をしっかり行う。

  3. 内耳老廃物排泄機構に着目した新機軸脳神経臨床画像診断の確立

    2017.4

    科学研究費補助金  基盤研究(B)

  4. Development of new dimensional clinical neuroimaging method based on the waste clearance system of inner ear

    Grant number:17H04259  2017.4 - 2020.3

    Naganawa Shinji

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    Authorship:Coinvestigator(s) 

    We have developed new MR pulse sequences that have extremely high sensitivity to low concentration gadolinium based contrast agent. Then we applied them to the patients with the suspicion of endolymphatic hydrops in the inner ear. We found and reported that the leakage of gadolinium to cerebrospinal fluid around cortical veins in the patients older than 37-years-old. As we accumulate many patients' data, we experienced some exceptional cases who shows leakage from younger period. Also we experienced the subjects without leakage in oldr subjects. We exnamined 190 cases, finally, we could find the cut-off value of 37.3-years-old from the receiver operating curve analysis. We have published this result on the journal "Magnetic Resonance in Medical Sciences". These results are gathering many attentions from neuroscience community as the objective biomaker of brain aging.

  5. Analysis of congenital deafness caused by a novel molecule to develop prevention and treatment

    Grant number:16K11177  2016.4 - 2019.3

    Sone Michihiko

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    Authorship:Principal investigator 

    Grant amount:\4680000 ( Direct Cost: \3600000 、 Indirect Cost:\1080000 )

    Congenital deafness appears at a rate of 1/1000 at birth, which is the most frequent disease among congenital disorders. Cochlear implantation is an efficient therapy, however, the existence of the spiral ganglion cell is fundamentally necessary. Recently, the molecule G attracts the worldwide attention because of its neurotrophic and migration properties.
    In order to obtain basic data concerning the development of prevision, prevention and treatment for congenital deafness, we analyzed the mechanism in which the molecule G could induce the congenital deafness. The study has demonstrated that the molecule G is essential factor for the development of the auditory function in mice.

  6. 神経堤細胞の制御遺伝子を標的にした加齢性難聴発症の予防・治療薬の開発

    2011.4 - 2014.3

    科学研究費補助金  基盤研究(C)

    曾根 三千彦

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    Authorship:Principal investigator 

  7. 遺伝子異常モデルマウスを用いた内耳血管条障害の解明と保護作用

    2007.4 - 2010.3

    科学研究費補助金  基盤研究(C)

    曽根 三千彦

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    Authorship:Principal investigator 

  8. 内外リンパの画像化と内耳病態の検索

    2007.4 - 2009.3

    科学研究費補助金  基盤研究(C)

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    Authorship:Coinvestigator(s) 

  9. 内耳障害に対する局所投与治療の向上のためのstrategy—遺伝子導入も含むー

    2002.4 - 2004.3

    科学研究費補助金  基盤研究(C)

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    Authorship:Principal investigator 

  10. レーザースペックルフローグラフィーを用いた内耳血流の画像評価

    Grant number:15390515  2001.4 - 2004.3

    文部省科学研究費 基盤研究B 

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    Authorship:Coinvestigator(s) 

  11. 内耳性難聴、耳鳴、めまいに対する局所療法に関する研究

    2000.4 - 2001.3

    文部省科学研究費 基盤研究B 

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    Authorship:Coinvestigator(s) 

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