Updated on 2024/03/20

写真a

 
TSUKAMOTO, Masaki
 
Organization
Graduate School of Informatics Department of Complex Systems Science 2 Lecturer
Graduate School
Graduate School of Information Science
Graduate School of Informatics
Undergraduate School
School of Informatics Department of Natural Informatics
Title
Lecturer
Contact information
メールアドレス
Homepage
http://www.is.nagoya-u.ac.jp/dep-cs/tsukamoto/index.html
External link

Degree 1

  1. Doctor of Science degree

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Research Areas 3

  1. Others / Others  / Synthetic Chemistry

  2. Others / Others  / Organic Chemistry

  3. Others / Others  / Chemistry Related to Living Body

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Current Research Project and SDGs 1

  1. 生体関連化合物の化学合成

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Research History 4

  1. Assistant Professor, Nagoya University

    2007.4

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    Country：Japan

  2. Research Associate, Nagoya University

    2003.4

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    Country：Japan

  3. Post-doctoral fellow, Universit Paris-Sud

    2001.9

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    Country：Japan

  4. JSPS Post-doctoral fellow, Nagoya University

    1999.4

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    Country：Japan

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Education 1

  1. Nagoya University   Graduate School of Science

    - 1999.3

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    Country： Japan

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Professional Memberships 3

  1. The Chemical Society of Japan

  2. The American Chemical Society

  3. The Society of Synthetic Organic Chemistry, Japan

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Papers 33

  1. Synthesis and Characterization of Maleimide-Terminated Oligoimides Formed by a Michael Addition Reaction Using Methoxybenzenes Reviewed

    T. Wakabayashi, S. Hor, K.-i. Oyama, and M. Tsukamoto

    Tetrahedron   Vol. 141   page： 133486   2023.5

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    Authorship：Last author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： https://doi.org/10.1016/j.tet.2023.133486

  2. Real-Time Monitoring of Enzyme-Catalyzed Phosphoribosylation of Anti-Influenza Prodrug Favipiravir by Time-Lapse NMR Spectroscopy. Reviewed

    T. Sugiki, A. Ito, Y. Hatanaka, M. Tsukamoto, T. Murata, K. Miyanishi, A. Kagawa, T. Fujiwara, M. Kitagawa, Y. Morita, and M. Negoro

    NMR Biomed.   Vol. 36 ( 5 ) page： e4888   2022.12

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： https://doi.org/10.1002/nbm.4888

  3. Characterization of Organic Friction Modifiers Using Lateral Force Microscopy and Eyring Activation Energy Model. Reviewed

    J. Hou, M. Tsukamoto, H. Zhang, K. Fukuzawa, S. Itoh, and N. Azuma

    Tribol. Int.   Vol. 178 ( Part A ) page： 108052   2022.11

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： https://doi.org/10.1016/j.triboint.2022.108052

  4. Molecules with a TEMPO-Based Head Group as High-Performance Organic Friction Modifiers. Reviewed

    J. Hou, M. Tsukamoto, S. Hor, X. Chen, J. Yang, H. Zhang, N. Koga, K. Yasuda, K. Fukuzawa, S. Itoh, and N. Azuma

    Friction   Vol. 11 ( 2 ) page： 316 - 332   2022.5

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： https://doi.org/10.1007/s40544-022-0610-0

  5. Synthesis and characterization of methoxybenzene-linked polyimides formed by 1,4-addition to bismaleimides Reviewed

    Seanghai Hor, Kin-ichi Oyama, Nobuaki Koga, and Masaki Tsukamoto

    Polymer   Vol. 238   page： 124326   2022.1

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    Authorship：Last author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： https://doi.org/10.1016/j.polymer.2021.124326

  6. Metal Ions Sensing by Biodots Prepared from DNA, RNA, and Nucleotides

    Wang Maofei, Tsukamoto Masaki, Sergeyev Vladimir G., Zinchenko Anatoly

    Biosensors   Vol. 11 ( 9 )   2021.9

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    Language：Japanese   Publisher：Biosensors  

    Nucleic acids that exhibit a high affinity toward noble and transition metal ions have attracted growing attention in the fields of metal ion sensing, toxic metal ion removal, and the construction of functional metal nanostructures. In this study, fluorescent nanoparticles (biodots) were synthesized from DNA, RNA, and RNA nucleotides (AMP, GMP, UMP, and CMP) using a hydrothermal (HT) method, in order to study their metal ion sensing characteristics. The fluorescent properties of biodots differ markedly between those prepared from purine and pyrimidine nucle-obases. All biodots demonstrate a high sensitivity to the presence of mercury cations (Hg2+ ), while biodots prepared from DNA, RNA, and guanosine monophosphate (GMP) are also sensitive to Ag+ and Cu2+ ions, but to a lesser extent. The obtained results show that biodots inherit the metal ion recognition properties of nucleobases, while the nucleobase composition of biodot precursors affects metal ion sensitivity and selectivity. A linear response of biodot fluorescence to Hg2+ concentration in solution was observed for AMP and GMP biodots in the range 0–250 µM, which can be used for the analytic detection of mercury ion concentration. A facile paper strip test was also developed that allows visual detection of mercury ions in solutions.

    DOI： 10.3390/bios11090333

    Web of Science

    Scopus

    PubMed

  7. Fluorescent Nanoparticles Synthesized from DNA, RNA, and Nucleotides Reviewed

    Wang Maofei, Tsukamoto Masaki, Sergeyev Vladimir G., Zinchenko Anatoly

    Nanomaterials   Vol. 11 ( 9 )   2021.9

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    Language：Japanese   Publisher：Nanomaterials  

    Ubiquitous on Earth DNA and other nucleic acids are being increasingly considered as promising biomass resources. Due to their unique chemical structure, which is different from that of a more common carbohydrate biomass polymers, materials based on nucleic acids may exhibit new attractive characteristics. In this study, fluorescent nanoparticles (biodots) were prepared by a hydrothermal (HT) method from various nucleic acids (DNA, RNA, nucleotides, and nucleosides) to establish the relationship between the structure of precursors and fluorescent properties of biodots and to optimize conditions for preparation of the most fluorescent product. HT treatment of nucleic acids results in decomposition of sugar moieties and depurination/depyrimidation of nucleobases, while their consequent condensation and polymerization gives fluorescent nanoparticles. Fluorescent properties of DNA and RNA biodots are drastically different from biodots synthesized from individual nucleotides. In particular, biodots synthesized from purine-containing nucleotides or nucleosides show up to 50-fold higher fluorescence compared to analogous pyrimidine-derived biodots. The polymeric nature of a precursor disfavors formation of a bright fluorescent product. The reported effect of the structure of the nucleic acid precursor on the fluorescence properties of biodots should help designing and synthesizing brighter fluorescent nanomaterials with broader specification for bioimaging, sensing, and other applications.

    DOI： 10.3390/nano11092265

    Web of Science

    Scopus

    PubMed

  8. Brønsted acid-catalyzed 1,4-addition of 1,3,5-trimethoxybenzene to maleimides and acrylates Reviewed

    Seanghai Hor, Kin-ichi Oyama, Nobuaki Koga, and Masaki Tsukamoto

    Tetrahedron Lett.   Vol. 74   page： Article 153100   2021.6

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    Authorship：Last author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/j.tetlet.2021.153100

  9. Experimental Study of Application of Molecules with a Cyclic Head Group Containing a Free Radical as Organic Friction Modifiers Reviewed

    X. Zhang, M. Tsukamoto, H. Zhang, Y. Mitsuya, S. Itoh, and K. Fukuzawa

    J. Adv. Mech. Des. Syst.   Vol. 14 ( 4 ) page： JAMDSM0044   2020.4

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1299/jamdsm.2020jamdsm0044

  10. Recent Application of Acidic 1,3-Azolium Salts as Promoters in the Solution-Phase Synthesis of Nucleosides and Nucleotides Invited Reviewed

    M. Tsukamoto and K.-i. Oyama

    Tetrahedron Lett.     page： 2477-2484   2018.6

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    Language：English  

    DOI： 10.1016/j.tetlet.2018.03.074

  11. A Solid-Supported Acidic Oxazolium Perchlorate as an Easy-Handling Catalyst for the Synthesis of Modified Pyrimidine Nucleosides via Vorbrüggen-type N-Glycosylation Reviewed

    N. Basu, K.-i. Oyama, and M. Tsukamoto

    Tetrahedron Lett.   Vol. 58 ( 20 ) page： 1921–1924   2017.5

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    Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/j.tetlet.2017.03.046

  12. Synthesis of Ribonucleoside 3',5'-Cyclic Monophosphorodithioates Reviewed

    A. Fukuhara and M. Tsukamoto

    Tetrahedron   Vol. 71 ( 23 ) page： 3878-3884   2015.6

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    Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/j.tet.2015.04.024

  13. Practical Synthesis of Adenosine 3',5'-Cyclic Monophosphorodithioate Reviewed

    A. Fukuhara, H. Morita, K.-i. Oyama, and M. Tsukamoto

    Tetrahedron Lett.   Vol. 55 ( 38 ) page： 5261-5263   2014.9

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/j.tetlet.2014.07.117

  14. Synthesis of Modified Pyrimidine Nucleosides via Vorbrüggen-type N-Glycosylation Catalyzed by 2-Methyl-5-phenylbenzoxazolium Perchlorate Reviewed

    H. Shirouzu, H. Morita, and M. Tsukamoto

    Tetrahedron   Vol. 70 ( 22 ) page： 3635-3639   2014.3

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    Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/j.tet.2014.03.013

  15. Cyclic Bis(3'-5')diadenylic Acid (c-di-AMP) Analogs Promote the Activities of Photosynthesis and Respiration of Chlamydomonas reinhardtii Reviewed

    T. Tezuka, H. Shirouzu, K. Ishida, N. Suzuki, T. Matsuo, K.-i. Oyama, S. Aoki, and M. Tsukamoto

    Am. J. Plant Sciences   Vol. 5 ( 1 ) page： 24-28   2014.1

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.4236/ajps.2014.51004

  16. Synthesis of 2'-Modified Cyclic Bis(3'-5')diadenylic Acids (c-di-AMPs) and Their Promotion of Cell Division in a Freshwater Green Alga Reviewed

    T. Tezuka, N. Suzuki, K. Ishida, K.-i. Oyama, S. Aoki, and M. Tsukamoto

    Chem. Lett.   Vol. 41 ( 12 ) page： 1723-1725   2012.12

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： doi:10.1246/cl.2012.1723

  17. Controlling Glycosyl Bond Conformation of Guanine Nucleosides: Stabilization of the anti Conformer in 5'-O-Ethylguanosine Reviewed

    H. Asami, S.-h. Urashima, M. Tsukamoto, A. Motoda, Y. Hayakawa, and H. Saigusa

    J. Phys. Chem. Lett.   Vol. 3   page： 571–575   2012.2

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1021/jz300081e

  18. Practical Synthesis of Cyclic Bis(3'-5') diadenylic Acid (c-di-AMP) Reviewed

    N. Suzuki, K.-i. Oyama, and M. Tsukamoto

    Chem. Lett.   Vol. 40 ( 10 ) page： 1113-1114   2011.9

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    Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： doi:10.1246/cl.2011.1113

  19. Gas-Phase Isolation of Diethyl Guanosine 5'-Monophosphate and Its Conformational Assignment Reviewed

    H. Asami, M. Tsukamoto, Y. Hayakawa, and H. Saigusa

    Phys. Chem. Chem. Phys.   Vol. 12 ( 42 ) page： 13918-13921   2010.11

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    Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1039/C0CP01105C

  20. Equilibrium of Homochiral Oligomerization of a Mixture of Enantiomers. Its Relevance to Nonlinear Effects in Asymmetric Catalysis Reviewed

    M. Tsukamoto, K. Gopalaiah, and H. B. Kagan

    J. Phy. Chem. B   Vol. 112 ( 48 ) page： 15361-15368   2008.12

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    Language：English   Publishing type：Research paper (scientific journal)  

  21. Enantiomeric products formed via different mechanisms: asymmetric hydrogenation of an α,β-unsaturated carboxylic acid involving a Ru(CH3COO)2[(R)-binap] catalyst Reviewed

    M. Yoshimura, Y. Ishibashi, K. Miyata, Y. Bessho, M. Tsukamoto, and M. Kitamura

    Tetrahedron   Vol. 63 ( 46 ) page： 11399-11409   2007.11

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    Language：English   Publishing type：Research paper (scientific journal)  

  22. Mechanism of Catalytic Asymmetric Hydrogenation of 2-Formyl-1-methylene-1,2,3,4-tetrahydroisoquinoline Using Ru(CH3COO)2[(S)-binap] Reviewed

    M. Tsukamoto, M. Yoshimura, K. Tsuda, and M. Kitamura

    Tetrahedron   Vol. 62 ( 23 ) page： 5448-5453   2006.6

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    Language：English   Publishing type：Research paper (scientific journal)  

  23. Origin of the Minor Enantiomeric Product in a Noyori Asymmetric Hydrogenation Reviewed

    Y. Ishibashi, Y. Bessho, M. Yoshimura, M. Tsukamoto, and M. Kitamura

    Angew. Chem. Int. Ed.   Vol. 44 ( 44 ) page： 7287-7290   2005.11

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    Language：English   Publishing type：Research paper (scientific journal)  

    The enantiomeric products of the catalytic hydrogenation of an isotopically labeled substrate were separated. The ratios of the isotopomers revealed that the major and minor enantiomers are formed mostly through different mechanisms. Hence, when analyzing the energy profile of an asymmetric catalytic reaction with the Arrhenius equation, two competing diastereomorphic catalytic cycles should be considered.

  24. Recent Advances of Mechanistic Studies on Asymmetric Hydrogenation of Dehydroamino Acid Derivatives Catalyzed by Diphosphine-Rh and -Ru Complexes Reviewed

    J. Synth. Org. Chem. Jpn.   Vol. 63 ( 9 ) page： 899-910   2005.9

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    Language：Japanese  

  25. Novel Synthesis and Characterization of Bioconjugate Block Copolymers Having Oligonucleotides Reviewed

    A. Noro, Y. Nagata, M. Tsukamoto, Y. Hayakawa, A. Takano, and Y. Matsushita

    Biomacromolecules   Vol. 6 ( 4 ) page： 2328-2333   2005

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    Language：English   Publishing type：Research paper (scientific journal)  

  26. Carboxylic Acids as Promoters for Internucleotide-Bond Formation via Condensation of a Nucleoside Phosphoramidite and a Nucleoside: Relationship between the Acidity and the Activity of the Promoter Reviewed

    Y. Hayakawa, T. Iwase, E. J. Nurminen, M. Tsukamoto, and M. Kataoka

    Tetrahedron   Vol. 61 ( 8 ) page： 2203-2209   2005

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    Language：English   Publishing type：Research paper (scientific journal)  

    The relationship between the activity and the acidity of a carboxylic acid as a promoter for condensation of a nucleoside phosphoramidite and a nucleoside was investigated. The investigation revealed that the acid, the pKa value of which in acetonitrile is less than 18, is capable of promoting the condensation reaction, and acid with a pKa value outside of this range does not serve as a promoter. In carboxylic acids serving as promoters, the ones with higher acidity generally show greater activity. In particular, acids with a pKa value less than ca. 16 (measured by a potentiometric method), such as trichloroacetic acid (pKaZ10.6), trifluoroacetic acid (pKaZ12.7), dichloroacetic acid (pKaZ13.2 or 15.8), and 2,4-dinitrobenzoic acid (pKaZ16.1), show high levels of activity higher than that of conventionally used 1H-tetrazole. These carboxylic acids generally serve as excellent promoters for both the liquid-phase and the solid-phase synthesis of oligonucleotides via phosphoramidite method.

  27. Is It Possible to Estimate the Enantioselectivity of a Chiral Catalyst from Its Racemic Mixture? Reviewed

    F. Lagasse, M. Tsukamoto, C. J. Welch, and H. B. Kagan

    J. Am. Chem. Soc.   Vol. 125 ( 25 ) page： 7490-7491   2003

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    Language：English   Publishing type：Research paper (scientific journal)  

  28. Recent Advances in the Measurement of Enantiomeric Excesses Reviewed

    M. Tsukamoto and H. B. Kagan

    Adv. Synth. Catal.   Vol. 344 ( 5 ) page： 453-463   2002

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  29. Mechanism of Asymmetric Hydrogenation of α-(Acylamino)acrylic Esters Catalyzed by BINAP-Ruthenium(II) Diacetate Reviewed

    M. Kitamura, M. Tsukamoto, Y. Bessho, M. Yoshimura, U. Kobs, M. Widhalm, and R. Noyori

    J. Am. Chem. Soc.   Vol. 124 ( 23 ) page： 6649-6667   2002

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    The mechanism of asymmetric hydrogenation of R-(acylamino)acrylic esters with Ru(CH3COO)2[(S)-binap] (BINAP ) 2,2′-bis(diphenylphosphino)-1,1′-binaphthyl), giving the S saturated products in more than 90 per cent enantiomeric excess, has been investigated by means of a kinetic study, deuterium labeling experiments, isotope effect measurements, and NMR and X-ray analysis of certain Ru complexes. The hydrogenation in methanol under a low H2 pressure proceeds via a monohydride-unsaturate mechanism that involves the initial RuH formation followed by a reaction with an olefinic substrate. The migratory insertion in the enamide-RuH chelate complex occurs reversibly and endergonically in an exo manner, giving a five-membered metallacycle intermediate. The cleavage of the Ru-C bond is achieved with either H2 (major) or CH3OH (minor). Both of the pathways result in overall cis hydrogenation products. The hydrogen at C(3) is mainly from an H2 molecule, and the C(2) hydrogen is from another H2 or protic CH3OH. The major S and minor R enantiomers are produced via the same mechanism involving diastereomeric intermediates. The turnover rate is limited by the step of hydrogenolysis of a half-hydrogenated metallacyclic intermediate. The participation of two different hydrogen donor molecules is in contrast to the pairwise dihydrogenation using a single H2 molecule in the Rh(I)-catalyzed reaction which occurs via a dihydride mechanism. In addition, the sense of asymmetric induction is opposite to that observed with (S)-BINAP-Rh(I) catalysts. The origin of this phenomenon is interpreted in terms of stereocomplementary models of the enamide/metal chelate complexes. A series of model stoichiometric reactions mimicking the catalytic steps has indicated that most NMR-observable Ru complexes are not directly involved in the catalytic hydrogenation but are reservoirs of real catalytic complexes or even side products that retard the reaction.

  30. Synthesis of α-Amino Phosphonic Acids by Asymmetric Hydrogenation Reviewed

    M. Kitamura, M. Yoshimura, M. Tsukamoto, and R. Noyori

    Enantiomer   Vol. 1 ( 4-6 ) page： 281-303   1996

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    Language：English   Publishing type：Research paper (scientific journal)  

  31. Conformational Study on 2-Acyl-1-alkylidene-1,2,3,4-tetrahydroisoquinolines Reviewed

    M. Kitamura, M. Tsukamoto, H. Takaya, and R. Noyori

    Bull. Chem. Soc. Jpn.   Vol. 69 ( 6 ) page： 1695-1700   1996

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    Language：English   Publishing type：Research paper (scientific journal)  

  32. General Asymmetric Synthesis of Isoquinoline Alkaloids. Enantioselective Hydrogenation of Enamides Catalyzed by BINAP-Ruthenium(II) Complexes Reviewed

    M. Kitamura, Yi Hsiao, M. Ohta, M. Tsukamoto, T. Ohta, H. Takaya, and R. Noyori

    J. Org. Chem.   Vol. 59 ( 2 ) page： 297-310   1994

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  33. Applicability of a Standardized Discrete Cosine Transform Coding Method to Character Images Reviewed

    Y. Hoshino, D. Ando, S. Higashino, and M. Tsukamoto

    J. Electronic Imaging   Vol. 1 ( 3 ) page： 322-327   1992

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    Language：English  

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Books 9

  1. ビスマレイミドへの炭素求核剤のマイケル付加反応によって生成するポリイミド

    塚本眞幸, 若林知紀, 尾山公一（ Role： Joint author ,  2023年5月号p46-51）

    シーエムシー出版  2023.5 

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    Total pages：6   Responsible for pages：46-51   Language：Japanese

  2. Reduction: Hydrogenation and Transfer Hydrogenation of C=C

    M. Tsukamoto and K.-i. Oyama（ Role： Contributor）

    Elsevier  2023.4 

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    Total pages：22   Responsible for pages：https://doi.org/10.1016/B978-0-32-390644-9.00044-5   Language：English Book type：Scholarly book

    DOI： https://doi.org/10.1016/B978-0-32-390644-9.00044-5

  3. Various Coupling Agents in the Phosphoramidite Method for Oligonucleotide Synthesis. In Synthesis of Therapeutic Oligonucleotides, S. Obika and M. Sekine, Eds.

    M. Tsukamoto and Y. Hayakawa（ Role： Contributor）

    Springer  2018.11 

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  4. Ferrocene, 1,1'-bis[(2R,4R)-2,4-diethyl-1-phosphetanyl]-, stereoisomer; Ferrocene, 1,1'-bis[(2S,4S)-2,4-diethyl-1-phosphetanyl]-, stereoisomer. In electronic-Encyclopedia of Reagents for Organic Synthesis.

    M. Tsukamoto and M. Kitamura（ Role： Contributor）

    Wiley  2013.9 

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    Language：English

  5. Reduction - Hydrogenation: C=C; Chemoselective. In Comprehensive Chirality, E. M. Carreira and H. Yamamoto, Eds.

    M. Tsukamoto and M. Kitamura（ Role： Contributor）

    Elsevier  2012.10  （ ISBN:978-0-08-095168-3 ）

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    Language：English

  6. Reduction by Homogenous Catalysis or Biocatalysis.

    M. Tsukamoto and M. Kitamura（ Role： Contributor）

    Thieme  2009.9 

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    Language：English

  7. Synthesis by Substitution. In "Science of Synthesis, Houben-Weyl Methods of Molecular Transformations", C. J. Forsyth, Ed.

    M. Tsukamoto and M. Kitamura（ Role： Contributor）

    Thieme  2008.5 

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  8. (R)- & (S)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl. First Update. In "Electronic Encyclopedia of Reagents for Organic Synthesis", L. A. Paquette, Ed.

    M. Tsukamoto and M. Kitamura（ Role： Contributor）

    John Wiley & Sons  2005.10 

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  9. Strategies Useful for the Chemical Synthesis of Oligonucleotides and Related Compounds. In "Frontiers in Organic Chemistry", Atta-Ur-Rahman and Y. Hayakawa, Eds.

    M. Tsukamoto and Y. Hayakawa（ Role： Contributor）

    Bentham  2005 

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Presentations 34

  1. 19Fおよび31P NMRスペクトルのタイムラプス測定による抗インフルエンザ薬ファビピラビルの酵素代謝のリアルタイムモニタリング

    杉木俊彦、伊藤彰厚、畑中悠子、塚本眞幸、村田剛志、宮西孝一郎、香川晃徳、藤原敏道、北川勝浩、森田靖、根来誠

    第62回NMR討論会 (2023)  2023.11.9 

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    Event date： 2023.11

    Language：Japanese   Presentation type：Oral presentation (general)  

  2. TEMPO系有機摩擦調整剤の表面吸着膜の構造とせん断強度に関する分子動力学解析

    森田 渓介、Foo Kimberly、陳 星宇、塚本 眞幸、張 賀東

    日本機械学会2023年度 年次大会  2023.9.4 

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    Event date： 2023.9

    Language：Japanese   Presentation type：Poster presentation  

  3. ミニトラクション試験機を用いたTEMPO系有機摩擦調整剤の性能評価

    侯金赤, 若林知紀, 塚本眞幸, 張賀東, 福澤健二, 伊藤伸太郎, 東直輝

    トライボロジー会議2023 春東京  2023.5.31  一般社団法人　日本トライボロジー学会

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    Event date： 2023.5

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：東京   Country：Japan  

  4. Synthesis and characterization of methoxybenzene-linked polyimides by 1,4-addition to bismaleimides

    Seanghai Hor, Kin-ichi Oyama, Nobuaki Koga, Masaki Tsukamoto

    The 102nd CSJ Annual Meeting (2022)  2022.3.24 

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    Event date： 2022.3

    Language：English   Presentation type：Oral presentation (general)  

  5. ガラスホストを用いた低温トリプレットDNPによる19Fスピンの高偏極化

    今若 寛己、畑中 悠子、宮西 孝一郎、香川 晃徳、根来 誠、塚本 眞幸、村田 剛志、森田 靖、北川 勝浩

    日本化学会 第102春季年会 (2022)  2022.3.26  公益社団法人 日本化学会

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    Event date： 2022.3

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：オンライン  

  6. 1,3,5-トリメトキシベンゼンのマレイミド類への1,4-付加反応

    HOR Seanghai, 尾山 公一, 古賀 伸明, 塚本 眞幸

    第52回 中部化学関係学協会支部連合協議会 (静岡)  2021.10.31  中部化学関係学協会支部連合協議会

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    Event date： 2021.10

    Presentation type：Poster presentation  

    Venue：オンライン   Country：Japan  

  7. 有機摩擦調整剤の表面吸着特性と摩擦摩 耗特性の相関に関する研究

    LOW HONG LIAN, Seanghai Hor，塚本眞幸，張賀東，福澤健二，伊藤伸太郎，東直輝

    トライボロジー会議2021 秋　松江  2021.10.29  日本トライボロジー学会

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    Event date： 2021.10

    Presentation type：Oral presentation (general)  

    Venue：オンライン   Country：Japan  

  8. 環状構造とラジカルを含む有機摩擦調整剤の性能に対する官能基の影響

    侯 金赤, Seanghai Hor, 塚本 眞幸, 張 賀東, 福澤 健二, 伊藤 伸太郎, 東 直輝

    日本機械学会2021年度年次大会  2021.9.6  日本機械学会

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    Event date： 2021.9

    Presentation type：Oral presentation (general)  

    Venue：オンライン   Country：Japan  

  9. 潤滑油中における有機摩擦調整剤の作用メカニズム解明のための表面吸着特性計測

    葛谷 光平, 張 賀東, 福澤 健二, 伊藤 伸太郎, 東 直輝, Seanghai Hor, 塚本 眞幸

    IIP2021 情報・知能・精密機器部門（IIP部門）講演会  2021.3  日本機械学会

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    Event date： 2021.3

    Presentation type：Oral presentation (general)  

    Venue：オンライン   Country：Japan  

    DOI： https://doi.org/10.1299/jsmeiip.2021.IIP1B1-2

  10. ラジカルを含む環状構造末端をもつ分子 の有機摩擦調整剤としての応用

    何海涛、塚本眞幸、Seanghai Hor、張賀東、三矢保永、福澤健二、伊藤伸太郎

    トライボロジー会議2020 秋 別府  2020.11.11 

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    Event date： 2020.11

    Presentation type：Oral presentation (general)  

  11. 酸アゾール複合体を促進剤に用いる反応の開発 Invited

    塚本　眞幸

    若手研究者のための有機化学札幌セミナー 

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    Event date： 2019.11

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：北海道大学　   Country：Japan  

  12. A Solid-Supported Acidic Oxazolium Perchlorate as a Heterogeneous Catalyst for N-Glycosylation Reactions

    M. Tsukamoto, N. Basu, and K.-i. Oyama

    The 44th International Symposium on Nucleic Acids Chemistry 

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    Event date： 2017.11

    Language：English   Presentation type：Poster presentation  

    Country：Japan  

  13. Synthesis of Ribonucleoside 3',5'-Cyclic Monophosphorodithioates International conference

    M. Tsukamoto, A. Fukuhara, H. Morita, and K.-i. Oyama

    The 42nd International Symposium on Nucleic Acids Chemistry 

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    Event date： 2015.9

    Language：English   Presentation type：Poster presentation  

    Country：Japan  

  14. アデノシン3',5'-環状モノホスホロジチオエートの合成

    福原充也, 森田裕紀, 尾山公一, 塚本眞幸

    第45回中部化学関係学協会支部連合秋季大会 

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    Event date： 2014.11

    Language：Japanese   Presentation type：Poster presentation  

    Country：Japan  

  15. 過塩素酸オキサゾリウム誘導体を触媒に用いるN-グリコシル化反応によるピリミジンヌクレオシドの合成

    森田裕紀, 白水宏, 塚本眞幸

    日本化学会第94春季年会 

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    Event date： 2014.3

    Language：Japanese   Presentation type：Poster presentation  

    Country：Japan  

  16. 環状ビス(3'-5')ジアデニル酸誘導体による緑藻の代謝活性の促進

    手塚修文, 森田裕紀, 白水宏, 石田啓悟, 鈴木紀尊, 塚本眞幸

    日本化学会第94春季年会 

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    Event date： 2014.3

    Language：Japanese   Presentation type：Poster presentation  

    Country：Japan  

  17. 2'-位を修飾した環状ジアデニル酸の合成およびそれらの生物活性

    手塚修文、鈴木紀尊、石田啓悟、尾山公一、青木摂之、塚本眞幸

    日本化学会第93春季年会 

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    Event date： 2013.3

    Language：Japanese   Presentation type：Poster presentation  

    Country：Japan  

  18. Synthesis of Cyclic Bis(3'-5')diadenylic Acid (c-di-AMP) and Its 2'-Modified Analogs International conference

    N. Suzuki, K.-i. Oyama and M. Tsukamoto

    Asian Core Program 2012 

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    Event date： 2012.12

    Language：English   Presentation type：Poster presentation  

    Country：Singapore  

  19. Synthesis of 2'-Modified Cyclic Bis(3'-5')diadenylic Acids (c-di-AMPs)

    H. Shirouzu, N. Suzuki, K.-i. Oyama, and M. Tsukamoto

    The 39th International Symposium on Nucleic Acids Chemistry 

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    Event date： 2012.11

    Language：English   Presentation type：Poster presentation  

    Country：Japan  

  20. 環状ジアデニル酸の効率的合成法の開発

    鈴木紀尊、尾山公一、塚本眞幸

    日本化学会第92春季年会 

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    Event date： 2012.3

    Language：Japanese   Presentation type：Poster presentation  

    Country：Japan  

  21. 核酸塩基関連分子のレーザー脱離パフォーマンスの改善： サンプルとマトリクス粒子のサイズ調整

    塚島史朗、浅見祐也、元田彩香、 塚本眞幸、早川芳宏、三枝洋之

    第5回分子科学討論会2011 

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    Event date： 2011.9

    Language：Japanese   Presentation type：Poster presentation  

    Country：Japan  

  22. Origin of the Minor Enantiomer in BINAP-Ru-catalyzed Hydrogenation of 3-Phenyl-2-butenoic Acid International conference

    Masaki Tsukamoto, Masahiro Yoshimura, Yoshitaka Ishibashi, Hiroshi Nakatsuka, and Masato Kitamura

    Pacifichem2010 

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    Event date： 2010.12

    Language：English   Presentation type：Poster presentation  

    Country：Japan  

  23. Non-destructive vaporization of GMP facilitated by the phosphoesterification: Conformational preference in the gas phase

    The 37th International Symposium on Nucleic Acids Chemistry 2010 

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    Event date： 2010.11

    Language：English   Presentation type：Poster presentation  

    Country：Japan  

  24. グアニンヌクレオチドのリン酸基エステル化による非破壊的気化と赤外振動分光

    浅見 祐也，元田 彩香，塚本 眞幸，早川 芳宏，三枝 洋之

    第4回分子科学討論会2010 

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    Event date： 2010.9

    Language：Japanese   Presentation type：Oral presentation (general)  

    Country：Japan  

  25. Intact laser desorption of guanosine 5'-monophosphate facilitated by the phosphoesterification - Conformational analysis by infrared vibrational spectroscopy

    Molecular and Ionic Clusters Conference 2010 

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    Event date： 2010.9

    Language：English   Presentation type：Poster presentation  

    Country：Japan  

  26. Mechanism of Catalytic Asymmetric Hydrogenation of 2-Formyl-1-methylene-1,2,3,4-tetrahydroisoquinoline Using Ru(CH3COO)2[(S)-binap] International conference

    The 17th International Conference on Organic Synthesis 

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    Event date： 2008.6

    Language：English   Presentation type：Poster presentation  

  27. c-di-GMPシグナルが及ぼすStreptococcus pyogenesのbiofilm形成性への影響

    亀ヶ谷太一, 山田景子, 岡本陽, 太田美智男, 早川 芳宏, 塚本 眞幸

    第81回日本細菌学会総会 

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    Event date： 2008.3

    Language：Japanese   Presentation type：Oral presentation (general)  

    Country：Japan  

  28. Mechanism of Asymmetric Hydrogenation of 2-Acyl-1-alkylidene-1,2,3,4-tetrahydroisoquinolines Catalyzed by BINAP-Ru(II) Diacetate

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    Event date： 2006.3

    Language：Japanese   Presentation type：Oral presentation (general)  

    Country：Japan  

  29. Internucleotide-linkage formation via the phosphoramidite method using a carboxylic acid as a promoter

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    Event date： 2004.11

    Language：Japanese   Presentation type：Oral presentation (general)  

    Country：Japan  

  30. BINAP–RhおよびRu錯体を触媒に用いるKagan反応の機構

    北村雅人、塚本眞幸、別所祐紀

    第44回天然有機化合物討論会 

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    Event date： 2002.10

    Language：Japanese   Presentation type：Poster presentation  

    Country：Japan  

  31. Structural Analysis of Complexes Related to Asymmetric Hydrogenation of (Z)-Methyl α-(Acetamido) Cinnamate Using Ru(CH3COO)2(binap) International conference

    2000 International Chemical Congress of Pacific Basin Societies 

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    Event date： 2000.12

    Language：English   Presentation type：Poster presentation  

  32. BINAP–Ruジアセタート錯体を触媒に用いるα-(アシルアミノ)アクリル酸エステル類の不斉水素化の機構

    北村雅人、塚本眞幸、吉村正宏、別所祐紀、野依良治

    第46回有機金属化学討論会 

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    Event date： 1999.9

    Language：Japanese   Presentation type：Oral presentation (general)  

    Country：Japan  

  33. BINAP–Ru錯体触媒を用いるエナミド類の不斉水素化

    北村雅人、塚本眞幸、肖毅、野依良治

    日本化学会第69春季年会 

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    Event date： 1995.3

    Language：Japanese   Presentation type：Oral presentation (general)  

    Country：Japan  

  34. 2-アシル-1-アルキリデン-1,2,3,4-テトラヒドロイソキノリン類の立体配座解析

    北村雅人、肖毅、塚本眞幸、野依良治

    日本化学会第67春季年会 

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    Event date： 1994.3

    Language：Japanese   Presentation type：Oral presentation (general)  

    Country：Japan  

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To the head of Presentations.▲

KAKENHI (Grants-in-Aid for Scientific Research) 5

  1. Precise Molecular Design of Organic Friction Modifiers by Large-Scale Molecular Simulations, Advanced Measurements, and Chemical Syntheses

    Grant number：21H01238  2021.4 - 2024.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)

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    Authorship：Coinvestigator(s) 

  2. グリーントライボロジーのための高性能な有機摩擦調整剤の創製

    Grant number：19K21915   2019.6 - 2021.3

    日本学術振興会  科学研究費補助金  挑戦的研究(萌芽)

    張賀東、塚本 眞幸

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    Authorship：Coinvestigator(s)  Grant type：Competitive

    Grant amount：\1800000 （ Direct Cost: \1800000 ）

  3. 酸アゾール複合体を触媒に用いる反応の開拓

    2014.4 - 2017.3

    科学研究費補助金  基盤研究(C)

    塚本 眞幸

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    Authorship：Principal investigator 

  4. 気相水和クラスターを用いた核酸塩基水和構造のモデリング：ヌクレオチドへの展開

    2013.4 - 2016.3

    科学研究費補助金  基盤研究(C)

    三枝 洋之

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    Authorship：Coinvestigator(s) 

  5. 環状ジアデニル酸の生理活性探索

    2010.4 - 2013.3

    科学研究費補助金  若手研究(B)

    塚本　眞幸

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    Authorship：Principal investigator 

To the head of KAKENHI (Grants-in-Aid for Scientific Research).▲
 

Teaching Experience (On-campus) 3

  1. 物質情報学9

    2020

  2. 物質情報学11

    2020

  3. 化学実験

    2020

To the head of Teaching Experience (On-campus).▲

Teaching Experience (Off-campus) 7

  1. 化学II

    2010.4 - 2011.3 （Aichi University of Education）

  2. 化学II

    2011.4 - 2012.3 （Aichi University of Education）

  3. 機器分析

    2011.4 - 2012.3 （Aichi University of Education）

  4. 化学II

    2012.4 - 2013.3 （Aichi University of Education）

  5. 機器分析

    2012.4 - 2013.3 （Aichi University of Education）

  6. 化学II

    2013.4 - 2014.3 （Aichi University of Education）

  7. 機器分析

    2013.4 - 2014.3 （Aichi University of Education）

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To the head of Teaching Experience (Off-campus).▲