論文 - 上野山 賀久
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Involvement of nuclear receptor corepressor 2 (NCOR2) in estrogen-induced repression of arcuate Kiss1 expression in female rats 査読有り
"Takizawa, M. Miyazaki, S. Tsuchida, H. Nagae, M. Seki, S. Hirabayashi, M. Osakada, F. Inoue, N. Tsukamura, H. Uenoyama, Y."
J Reprod Dev 2025年1月
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AVPV Kiss1 neuron-specific knockdown of purinergic P2X2 receptor suppresses LH surge and ovulation in Kiss1-Cre rats 招待有り 査読有り
"Hazim, S. Seki, S. Yabushita, R. Nagae, M. Tsuchida, H. Hirabayashi, M. Uenoyama, Y. Tsukamura, H. Inoue, N."
J Reprod Dev 70 巻 ( 6 ) 頁： 379 - 388 2024年12月
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Absence of sex differences in diabetes-induced suppression of KNDy neurons in rats 査読有り
Otsuka M, Iwata K, Otsuka Y, Uenoyama Y, Ozawa H, Ishii H
J Endocrinol 2024年10月
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Central δ/κ opioid receptor signaling pathways mediate chronic and/or acute suckling-induced LH suppression in rats during late lactation 査読有り
Uenoyama Y, Nonogaki M, Tsuchida H, Takizawa M, Matsuzaki S, Inoue N, Tsukamura H
J Reprod Dev 2024年8月
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Raphe glucose-sensing serotonergic neurons stimulate KNDy neurons to enhance LH pulses via 5HT2CR: rat and goat studies 査読有り
Nakamura S, Sasaki T, Uenoyama Y, Inoue N, Nakanishi M, Yamada K, Morishima A, Suzumura R, Kitagawa Y, Morita Y, Ohkura S, Tsukamura H
Scientific Reports 14 巻 頁： 10190 2024年5月
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Neonatal aromatase inhibition blocked defeminization of AVPV Kiss1 neurons and LH surge-generating system in male rats 査読有り
Yamada K, Mano T, Hazim S, Takizawa M, Inoue N, Uenoyama Y, Tsukamura H
Endocrinology 165 巻 ( 4 ) 2024年3月
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Capturing temperature changes on the ocular surface along with estrus and ovulation using infrared thermography in Japanese Black cows 査読有り
Ozaki R, Inoue S, Yorozui Y, Ichikawa R, Yamada N, Higashi S, Matsuyama S, Tsukamura H, Ohkura S, Uenoyama Y, Morita Y
J Reprod Dev 70 巻 ( 1 ) 頁： 49 - 54 2023年11月
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Conditional Oprk1-dependent Kiss1 deletion in kisspeptin neurons caused estrogen-dependent LH pulse disruption and LH surge attenuation in female rats 査読有り
Nagae M, Yamada K, Enomoto Y, Kometani M, Tsuchida H, Panthee A, Nonogaki M, Matsunaga N, Takizawa M, Matsuzaki S, Hirabayashi M, Inoue N, Tsukamura H, Uenoyama Y
Scientific Reports 13 巻 ( 1 ) 2023年11月
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Sex difference in developmental changes in visualized Kiss1 neurons in newly generated Kiss1-Cre rats 査読有り
Yamada K, Nagae M, Mano T, Tsuchida H, Hazim S, Goto T, Sanbo M, Hirabayashi M, Inoue N, Uenoyama Y, Tsukamura H
J Reprod Dev 69 巻 ( 5 ) 頁： 227 - 238 2023年7月
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Enkephalin-δ opioid receptor signaling partly mediates suppression of LH release during early lactation in rats 査読有り
Tsuchida H, Takizawa M, Nonogaki M, Inoue N, Uenoyama Y, Tsukamura H
J Reprod Dev 69 巻 ( 4 ) 2023年6月
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Kisspeptin and lactational anestrus: Current understanding and future prospects 招待有り 査読有り
Uenoyama Y, Inoue N, Tsukamura H
Peptides 166 巻 2023年5月
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KNDy neurones and GnRH/LH pulse generation: Current understanding and future aspects 招待有り 査読有り
Uenoyama Y, Tsukamura H
J Neuroendocrinol 35 巻 2023年5月
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Hindbrain Adenosine 5-Triphosphate (ATP)-Purinergic Signaling Triggers LH Surge and Ovulation via Activation of AVPV Kisspeptin Neurons in Rats. 査読有り
Inoue N, Hazim S, Tsuchida H, Dohi Y, Ishigaki R, Takahashi A, Otsuka Y, Yamada K, Uenoyama Y, Tsukamura H
The Journal of neuroscience 43 巻 ( 12 ) 頁： 2140 - 2152 2023年3月
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Enkephalin-δ Opioid Receptor Signaling Mediates Glucoprivic Suppression of LH Pulse and Gluconeogenesis in Female Rats. 査読有り
Tsuchida H, Nonogaki M, Takizawa M, Inoue N, Uenoyama Y, Tsukamura H
Endocrinology 164 巻 ( 3 ) 2023年1月
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Intronic Enhancer Is Essential for Nr5a1 Expression in the Pituitary Gonadotrope and for Postnatal Development of Male Reproductive Organs in a Mouse Model 招待有り 査読有り
Shima Yuichi, Miyabayashi Kanako, Mori Takami, Ono Koji, Kajimoto Mizuki, Cho Hae Lim, Tsuchida Hitomi, Uenoyama Yoshihisa, Tsukamura Hiroko, Suzuki Kentaro, Choi Man Ho, Toida Kazunori
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 24 巻 ( 1 ) 2023年1月
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Dynorphin-Kappa-opioid receptor signaling, but not mu-opioid receptor signaling, partly mediates the suppression of luteinizing hormone release during late lactation in rats 招待有り 査読有り
Tsuchida Hitomi, Nonogaki Miku, Inoue Naoko, Uenoyama Yoshihisa, Tsukamura Hiroko
Neuroscience letters 791 巻 頁： 136920 2022年11月
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Establishment of embryo transfer in the musk shrew (Suncus murinus). 査読有り
Inoue N, Hotta A, Goto T, Hirabayashi M, Uenoyama Y, Tsukamura H
The Journal of reproduction and development 66 巻 ( 5 ) 頁： 340 - 344 2022年10月
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Opioidergic pathways and kisspeptin in the regulation of female reproduction in mammals 招待有り 査読有り
Uenoyama Y, Tsuchida H, Nagae M, Inoue N, Tsukamura H
Front Neurosci 16 巻 頁： 958377 2022年9月
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A Survey of Genome-Wide Genetic Characterizations of Crossbred Dairy Cattle in Local Farms in Cambodia 招待有り 査読有り 国際共著
Somony Mam, Bengthay Tep, Soriya Rin, Yoshihisa Uenoyama, Shuichi Matsuyama, Satoshi Ohkura, Tetsuma Murase, Mitsuo Nunome, Yasuhiro Morita
Animals 12 巻 ( 16 ) 頁： 2072 2022年8月
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Central somatostatin-somatostatin receptor 2 signaling mediates lactational suppression of luteinizing hormone release via the inhibition of glutamatergic interneurons during late lactation in rats 査読有り
Sugimoto A, Tsuchida H, Nagae M, Inoue N, Uenoyama Y, Tsukamura H
J Reprod Dev 68 巻 ( 3 ) 頁： 190 - 197 2022年6月
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Generation of Tfap2c-T2A-tdTomato knock-in reporter rats via adeno-associated virus-mediated efficient gene targeting 査読有り
Oikawa M, Nagae M, Mizuno N, Iwatsuki K, Yoshida F, Inoue N, Uenoyama Y, Tsukamura H, Nakauchi H, Hirabayashi M, Kobayashi T
Mol Reprod Dev 89 巻 頁： 129–132 2022年2月
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Kiss1-dependent and independent release of luteinizing hormone and testosterone in perinatal male rats 査読有り
Chen J, Minabe S, Munetomo A, Magata F, Sato M, Nakamura S, Hirabayashi M, Ishihara Y, Yamazaki T, Uenoyama Y, Tsukamura H, Matsuda F
Endocrine Journal 2022年2月
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Cellular and molecular mechanisms regulating the KNDy neuronal activities to generate and modulate GnRH pulse in mammals 査読有り
Ikegami K, Watanabe Y, Nakamura S, Goto T, Inoue N, Uenoyama Y, Tsukamura H
Front Neuroendocrinol 64 巻 頁： 100968 2021年11月
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Kisspeptin neurons as a key player bridging the endocrine system and sexual behavior in mammals 査読有り
Nakamura S, Watanabe Y, Goto T, Ikegami K, Inoue N, Uenoyama Y, Tsukamura H
Front Neuroendocrinol 64 巻 頁： 100952 2021年11月
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Role of KNDy neurons expressing kisspeptin, neurokinin B, and dynorphin A as a GnRH pulse generator controlling mammalian reproduction 査読有り
Uenoyama Y, Nagae M, Tsuchida H, Inoue N, Tsukamura H
Front Endocrinol (Lausanne) 12 巻 頁： 724632 2021年9月
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Kisspeptin neurons and estrogen-estrogen receptor α signaling: Unraveling the mystery of steroid feedback system regulating mammalian reproduction 査読有り
Uenoyama Y, Inoue N, Nakamura S, Tsukamura H
Int J Mol Sci 22 巻 頁： 9229 2021年9月
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Central μ-opioid receptor antagonism blocks glucoprivic LH pulse suppression and gluconeogenesis/feeding in female rats 査読有り
Tsuchida H, Kawai N, Yamada K, Takizawa M, Inoue N, Uenoyama Y, Tsukamura H
Endocrinology 162 巻 頁： bqab140 2021年7月
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Morphological Analysis of the Hindbrain Glucose Sensor-Hypothalamic Neural Pathway Activated by Hindbrain Glucoprivation 査読有り
Sato M, Minabe S, Sakono T, Magata F, Nakamura S, Watanabe Y, Inoue N, Uenoyama Y, Tsukamura H, Matsuda F
Endocrinology 162 巻 頁： bqab125 2021年6月
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Reduction of arcuate kappa-opioid receptor-expressing cells increased luteinizing hormone pulse frequency in female rats 査読有り
Dai M, Nakamura S, Takahashi C, Sato M, Munetomo A, Magata F, Uenoyama Y, Tsukamura H, Matsuda F
Endocr J 2021年4月
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Direct evidence that KNDy neurons maintain gonadotropin pulses and folliculogenesis as the GnRH pulse generator. 査読有り
Nagae M, Uenoyama Y, Okamoto S, Tsuchida H, Ikegami K, Goto T, Majarune S, Nakamura S, Sanbo M, Hirabayashi M, Kobayashi K, Inoue N, Tsukamura H
Proceedings of the National Academy of Sciences of the United States of America 118 巻 ( 5 ) 頁： e2009156118 2021年2月
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Paraventricular Dynorphin A Neurons Mediate LH Pulse Suppression Induced by Hindbrain Glucoprivation in Female Rats. 査読有り
Tsuchida H, Mostari P, Yamada K, Miyazaki S, Enomoto Y, Inoue N, Uenoyama Y, Tsukamura H
Endocrinology 161 巻 ( 11 ) 2020年11月
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Facilitatory and inhibitory role of central amylin administration in the regulation of the gonadotropin-releasing hormone pulse generator activity in goats 査読有り
Kitagawa Y, Sasaki T, Suzumura R, Morishima A, Tatebayashi R, Assadullah, Ieda N, Morita Y, Matsuyama S, Inoue N, Uenoyama Y, Tsukamura H, Ohkura S
Neuroscience Letters 736 巻 頁： 135276 2020年9月
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Mating-induced increase in Kiss1 mRNA expression in the anteroventral periventricular nucleus prior to an increase in LH and testosterone release in male rats. 査読有り
Watanabe Y, Ikegami K, Nakamura S, Uenoyama Y, Ozawa H, Maeda KI, Tsukamura H, Inoue N
The Journal of Reproduction and Development 66 巻 頁： 579 - 586 2020年9月
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Testosterone Supplementation Rescues Spermatogenesis and In Vitro Fertilizing Ability of Sperm in Kiss1 Knockout Mice 査読有り
Goto T, Hirabayashi M, Watanabe Y, Sanbo M, Tomita K, Inoue N, Tsukamura H, Uenoyama Y
Endocrinology 161 巻 ( 9 ) 頁： bqaa092 2020年9月
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Conditional kisspeptin neuron-specific Kiss1 knockout with newly generated Kiss1-floxed and Kiss1-Cre mice replicates a hypogonadal phenotype of global Kiss1 knockout mice. 査読有り
Ikegami K, Goto T, Nakamura S, Watanabe Y, Sugimoto A, Majarune S, Horihata K, Nagae M, Tomikawa J, Imamura T, Sanbo M, Hirabayashi M, Inoue N, Maeda KI, Tsukamura H, Uenoyama Y
The Journal of Reproduction and Development 66 巻 ( 4 ) 頁： 359 - 367 2020年8月
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Inducible Kiss1 knockdown in the hypothalamic arcuate nucleus suppressed pulsatile secretion of luteinizing hormone in male mice. 査読有り
Minabe S, Nakamura S, Fukushima E, Sato M, Ikegami K, Goto T, Sanbo M, Hirabayashi M, Tomikawa J, Imamura T, Inoue N, Uenoyama Y, Tsukamura H, Maeda KI, Matsuda F
The Journal of Reproduction and Development 66 巻 ( 4 ) 頁： 369 - 375 2020年8月
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Peripheral administration of SB223412, a selective neurokinin-3 receptor antagonist, suppresses pulsatile luteinizing hormone secretion by acting on the gonadotropin-releasing hormone pulse generator in estrogen-treated ovariectomized female goats. 査読有り
Sasaki T, Sonoda T, Tatebayashi R, Kitagawa Y, Oishi S, Yamamoto K, Fujii N, Inoue N, Uenoyama Y, Tsukamura H, Maeda KI, Matsuda F, Morita Y, Matsuyama S, Ohkura S
The Journal of Reproduction and Development 66 巻 ( 4 ) 頁： 351 - 357 2020年8月
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Establishment of immortalised cell lines derived from female Shiba goat KNDy and GnRH neurones 査読有り
Suetomi Y, Tatebayashi R, Sonoda S, Munetomo A, Matsuyama S, Inoue N, Uenoyama Y, Takeuchi Y, Tsukamura H, Ohkura S, Matsuda F
Journal of Neuroendocrinology 32 巻 ( 6 ) 頁： e12857 2020年6月
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GnRH(1-5), a metabolite of gonadotropin-releasing hormone, enhances luteinizing hormone release via activation of kisspeptin neurons in female rats 査読有り
Ieda N, Assadullah, Minabe S, Ikegami K, Watanabe Y, Sugimoto Y, Sugimoto A, Kawai N, Ishii H, Inoue N, Uenoyama Y, Tsukamura H
Endocrine Journal 67 巻 ( 4 ) 頁： 409 - 418 2020年4月
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Seasonal changes in the reproductive performance in local cows receiving artificial insemination in the Pursat province of Cambodia. 査読有り 国際共著
Tep B, Morita Y, Matsuyama S, Ohkura S, Inoue N, Tsukamura H, Uenoyama Y, Pheng V
Asian-Australasian Journal of Animal Sciences 2020年4月
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Retinoblastoma binding protein 7 is involved in Kiss1 mRNA upregulation in rodents. 査読有り
Horihata K, Inoue N, Uenoyama Y, Maeda KI, Tsukamura H
The Journal of Reproduction and Development 66 巻 ( 2 ) 頁： 125 - 133 2020年4月
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Role of kisspeptin neurons as a GnRH surge generator: Comparative aspects in rodents and non-rodent mammals 査読有り
Matsuda F, Ohkura S, Magata F, Munetomo A, Chen J, Sato M, Inoue N, Uenoyama Y, Tsukamura H
Journal Of Obstetrics And Gynaecology Research 45 巻 ( 12 ) 頁： 2318 - 2329 2019年12月
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Ad libitum feeding triggers puberty onset associated with increases in arcuate Kiss1 and Pdyn expression in growth-retarded rats. 査読有り
Majarune S, Nima P, Sugimoto A, Nagae M, Inoue N, Tsukamura H, Uenoyama Y
The Journal of reproduction and development 65 巻 ( 5 ) 頁： 397-406 2019年10月
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Peripheral administration of kappa-opioid receptor antagonist stimulates gonadotropin-releasing hormone pulse generator activity in ovariectomized, estrogen-treated female goats
Sasaki T., Ito D., Sonoda T., Morita Y., Wakabayashi Y., Yamamura T., Okamura H., Oishi S., Noguchi T., Fujii N., Uenoyama Y., Tsukamura H., Maeda K. I, Matsuda F., Ohkura S.
DOMESTIC ANIMAL ENDOCRINOLOGY 68 巻 頁： 83-91 2019年7月
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Central Mechanism Controlling Pubertal Onset in Mammals: A Triggering Role of Kisspeptin
Uenoyama Y, Inoue N, Nakamura S, Tsukamura H
FRONTIERS IN ENDOCRINOLOGY 10 巻 頁： 312 2019年5月
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Neonatal Estrogen Causes Irreversible Male Infertility via Specific Suppressive Action on Hypothalamic Kiss1 Neurons
Minabe Shiori, Sato Marimo, Inoue Naoko, Watanabe Youki, Magata Fumie, Matsuda Fuko, Uenoyama Yoshihisa, Ozawa Hitoshi, Tsukamura Hiroko
ENDOCRINOLOGY 160 巻 ( 5 ) 頁： 1223-1233 2019年5月
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Morphological analysis for neuronal pathway from the hindbrain ependymocytes to the hypothalamic kisspeptin neurons.
Deura C, Minabe S, Ikegami K, Inoue N, Uenoyama Y, Maeda KI, Tsukamura H
The Journal of reproduction and development 65 巻 ( 2 ) 頁： 129-137 2019年4月
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Kisspeptin: A Central Regulator of Reproduction in Mammals 招待有り 査読有り
Ieda N, Hassaneen ASA, Inoue N, Uenoyama Y, Tsukamura H
SVU- International Journal of Veterinary Sciences 3. 巻 ( 1 ) 頁： 10 - 26 2019年
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Study on the Reproductive Performance and Problems in Crossbred Cows in Jalalabad, East of Afghanistan 招待有り 査読有り
Assadullah, Ieda N, Bayer DM, Stanikzai PM, Memlawal R, Inoue N, Uenoyama Y, Tsukamura H
J Intl Cooper Agric Dev 17 巻 頁： 2 - 7 2019年
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The roles of kisspeptin in the mechanism underlying reproductive functions in mammals.
Uenoyama Y, Inoue N, Maeda KI, Tsukamura H
The Journal of reproduction and development 2018年10月
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Co-expression of the calcitonin receptor gene in the hypothalamic kisspeptin neurons in female rats.
Assadullah, Ieda N, Kawai N, Ishii H, Ihara K, Inoue N, Uenoyama Y, Tsukamura H
Reproductive medicine and biology 17 巻 ( 2 ) 頁： 164-172 2018年4月
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Somatostatin-Somatostatin Receptor 2 Signaling Mediates LH Pulse Suppression in Lactating Rats
Sugimoto A, Tsuchida H, Ieda N, Ikegami K, Inoue N, Uenoyama Y, Tsukamura H
ENDOCRINOLOGY 160 巻 ( 2 ) 頁： 473 - 483 2018年
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SB223412, a neurokinin-3 receptor-selective antagonist, suppresses testosterone secretion in male guinea pigs
Nakamura Sho, Ito Yoshiko, Yamamoto Koki, Takahashi Chudai, Dai Mingdao, Tanahashi Miyu, Uenoyama Yoshihisa, Tsukamura Hiroko, Oishi Shinya, Maeda Kei-ichiro, Matsuda Fuko
THERIOGENOLOGY 102 巻 頁： 183-189 2017年
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Long-Term Neonatal Estrogen Exposure Causes Irreversible Inhibition of LH Pulses by Suppressing Arcuate Kisspeptin Expression via Estrogen Receptors alpha and beta in Female Rodents
Minabe Shiori, Ieda Nahoko, Watanabe Youki, Inoue Naoko, Uenoyama Yoshihisa, Maeda Kei-ichiro, Tsukamura Hiroko
ENDOCRINOLOGY 158 巻 ( 9 ) 頁： 2918-2929 2017年
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Evolutionally Conserved Function of Kisspeptin Neuronal System Is Nonreproductive Regulation as Revealed by Nonmammalian Study
Nakajo Mikoto, Kanda Shinji, Karigo Tomomi, Takahashi Akiko, Akazome Yasuhisa, Uenoyama Yoshihisa, Kobayashi Makito, Oka Yoshitaka
ENDOCRINOLOGY 159 巻 ( 1 ) 頁： 163-183 2017年
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Evidence of involvement of neurone-glia/neurone-neurone communications via gap junctions in synchronised activity of KNDy neurones
Ikegami K., Minabe S., Ieda N., Goto T., Sugimoto A., Nakamura S., Inoue N., Oishi S., Maturana A. D., Sanbo M., Hirabayashi M., Maeda K-I, Tsukamura H., Uenoyama Y.
JOURNAL OF NEUROENDOCRINOLOGY 29 巻 ( 6 ) 2017年
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Evaluation of heat stress response in crossbred dairy cows under tropical climate by analysis of heart rate variability
Bun Chan, Watanabe Youki, Uenoyama Yoshihisa, Inoue Naoko, Ieda Nahoko, Matsuda Fuko, Tsukamura Hiroko, Kuwahara Masayoshi, Maeda Kei-ichiro, Ohkura Satoshi, Pheng Vutha
JOURNAL OF VETERINARY MEDICAL SCIENCE 80 巻 ( 1 ) 頁： 181-185 2017年
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Enhancement of the luteinising hormone surge by male olfactory signals is associated with anteroventral periventricular Kiss1 cell activation in female rats
Watanabe Y, Ikegami K, Ishigaki R, Ieda N, Uenoyama Y, Maeda KI, Tsukamura H, Inoue N
JOURNAL OF NEUROENDOCRINOLOGY 29 巻 ( 8 ) 2017年
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CRISPR/Cas9-mediated genome editing in wild-derived mice: generation of tamed wild-derived strains by mutation of the a (nonagouti) gene
Hirose M, Hasegawa A, Mochida K, Matoba S, Hatanaka Y, Inoue K, Goto T, Kaneda H, Yamada I, Furuse T, Abe K, Uenoyama Y, Tsukamura H, Wakana S, Honda A, Ogura A
SCIENTIFIC REPORTS 7 巻 頁： 42476 2017年
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Characterization of smallholder livestock farming in Kampong Cham province, Cambodia -A pilot study in Prey Chhor district-. 招待有り 査読有り
Ieda N, Watanabe Y, Bun C, Pheng V, Uenoyama Y
J Intl Cooper Agric Dev 15 巻 頁： 42 - 47 2017年
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Immunohistochemical characterization of the arcuate kisspeptin/neurokinin B/dynorphin (KNDy) and preoptic kisspeptin neuronal populations in the hypothalamus during the estrous cycle in heifers 査読有り
Hassaneen ASA, Naniwa Y, Suetomi Y, Matsuyama S, Kimura K, Ieda N, Inoue N, Uenoyama Y, Tsukamura H, Maeda K-I, Matsuda F, Ohkura S
J Reprod Dev 62 巻 頁： 471-477 2016年
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The roles of kisspeptin revisited: inside and outside the hypothalamus 招待有り 査読有り
Uenoyama Y, Pheng V, Tsukamura H, Maeda K.
J Reprod Dev 62 巻 頁： 537-545 2016年
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Neonatal kisspeptin is steroid-independently required for defeminisation and peripubertal kisspeptin-induced testosterone is required for masculinisation of the brain 査読有り
Nakamura S, Uenoyama Y, Ikegami K, Dai M, Watanabe Y, Takahashi C, Hirabayashi M, Tsukamura H, Maeda KI.
J Neuroendocrinol 頁： 10.1111/jne.12409 2016年
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Molecular and epigenetic mechanism regulating hypothalamic Kiss1 gene expression in mammals 招待有り 査読有り
Uenoyama Y, Tomikawa J, Inoue N, Goto T, Minabe S, Ieda N, Nakamura S, Watanabe Y, Ikegami K, Matsuda F, Ohkura S, Maeda KI, Tsukamura H
Neuroendocrinology 103 巻 頁： 640 - 649 2016年
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Pharmacological and morphological evidence of AMPK-mediated energy sensing in the lower brain stem ependymocytes to control reproduction in female rodents 査読有り
Minabe S, Deura C, Ikegami K, Goto T, Sanbo M, Hirabayashi M, Inoue N, Uenoyama Y, Maeda KI, Tsukamura H
Endocrinology 156 巻 頁： 2278-2287 2015年6月
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The LH surge-generating system is functional in male goats as in females: involvement of kisspeptin neurones in the medial preoptic area
Matsuda, F., Nakatsukasa, K., Suetomi, Y., Naniwa, Y., Ito, D., Inoue, N., Wakabayashi, Y., Okamura, H., Maeda, K.I., Uenoyama, Y., Tsukamura, H. and Ohkura, S.
J. Neuroendocrinol. 27 巻 頁： 57-65 2015年
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Identification of hypothalamic arcuate nucleus-specific enhancer region of Kiss1 gene in mice 査読有り
Goto, T., Tomikawa, J., Ikegami, K., Minabe, S., Abe, H., Fukanuma, T., Imamura, T., Takase, K., Sanbo, M., Tomita, K., Hirabayashi, M., Maeda, K.I., Tsukamura, H. and Uenoyama, Y.
Mol. Endocrinol. 29 巻 頁： 121-129 2015年
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Lack of pulse and surge modes and glutamatergic stimulation of LH release in Kiss1 knockout rats. 査読有り
Uenoyama Y, Nakamura S, Hayakawa Y, Ikegami K, Watanabe Y, Deura C, Minabe S, Tomikawa J, Goto T, Ieda N, Inoue N, Sanbo M, Tamura C, Hirabayashi M, Maeda KI, Tsukamura H
J. Neuroendocrinol. 27 巻 頁： 187 - 197 2015年
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Central estrogen action sites involved in prepubertal restraint of pulsatile luteinizing hormone release in female rats 査読有り
Uenoyama Y, Tanaka A, Takase K, Yamada S, Pheng V, Inoue N, Maeda KI, Tsukamura H
Journal of Reproduction and Development 61 巻 頁： 351-359 2015年
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Design and synthesis of fluorescent probes for GPR54
Kaneda, M., Misu, R., Ohno, H., Hirasawa, A., Ieda, N., Uenoyama, Y., Tsukamura, H., Maeda, K.I., Oishi, S. and Fujii, N.
Bioorg. Med. Chem. 22 巻 頁： 3325-3330 2014年
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KISS1 gene expression in the developing brain of female pigs in pre- and peripubertal periods.
Ieda, N., Uenoyama, Y., Tajima, Y., Nakata, T., Kano, M., Naniwa, Y., Watanabe, Y., Minabe, S., Tomikawa, J., Inoue, N., Matsuda, F., Ohkura, S., Maeda, K.I. and Tsukamura, H
J. Reprod. Dev. 60 巻 頁： 312-316 2014年
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Oestrogen-induced activation of preoptic kisspeptin neurones may be involved in the luteinizing hormone surge in male and female Japanese monkeys
Watanabe, Y., Uenoyama, Y., Suzuki, J., Takase, K., Suetomi, Y., Ohkura, S., Inoue, N., Maeda, K.I. and Tsukamura, H
J. Neuroendocrinol. 26 巻 頁： 909-917 2014年
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KNDy neuron as a gatekeeper of puberty onset 招待有り 査読有り
Uenoyama Y, Tsukamura H, Maeda KI
J Obstet Gynaecol Res 40 巻 頁： 1518 - 1526 2014年
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Microarray Analysis of Perinatal-Estrogen-Induced Changes in Gene Expression Related to Brain Sexual Differentiation in Mice
Sakakibara M, Uenoyama Y, Minabe S, Watanabe Y, Deura C, Nakamura S, Suzuki G, Maeda K-I and Tsukamura H
PLoS ONE 8 巻 頁： e79437 2013年11月
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Effects of Full-Length Kisspeptin Administration on Follicular Development in Japanese Black Beef Cows
Naniwa Y, Nakatsukasa K, Setsuda S, Oishi S, Fujii N, Matsuda F, Uenoyama Y, Tsukamura H, Maeda KI, Ohkura S
J Reprod Dev 59 巻 頁： 588–594 2013年8月
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Chronic peripheral administration of kappa-opioid receptor antagonist advances puberty onset associated with acceleration of pulsatile luteinizing hormone secretion in female rats
Nakahara T, Uenoyama Y, Iwase A, Oishi S, Nakamura S, Minabe S, Watanabe Y, Deura C, Noguchi T, Fujii N, Kikkawa F, Maeda KI, Tsukamura H
J Reprod Dev 59 巻 頁： 479-484 2013年6月
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Molecular cloning and identification of the transcriptional regulatory domain of the goat neurokinin B Gene TAC3
Suetomi Y, Matsuda F, Uenoyama Y, Maeda KI, Tsukamura H, Ohkura S
J Reprod Dev 59 巻 頁： 463-469 2013年3月
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Dynorphin-kappa opioid receptor signaling partly mediates estrogen negative feedback effect on LH pulses in female rats 査読有り
Mostari MP, Ieda N, Deura C, Minabe S, Yamada S, Uenoyama Y, Maeda KI, Tsukamura H
59 巻 頁： 266–272 2013年1月
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Central distribution of kiss2 neurons and peri-pubertal changes in their expression in the brain of male and female red seabream Pagrus major
Shimizu Y, Tomikawa J, Hirano K, Nanikawa Y, Akazome Y, Kanda S, Kazeto Y, Okuzawa K, Uenoyama Y, Ohkura S, Tsukamura H, Maeda KI, Gen K, Oka Y, Yamamoto N
Gen Comp Endocrinol 175 巻 頁： 432-442 2012年
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Epigenetic regulation of Kiss1 gene expression mediating estrogen-positive feedback action in the mouse brain
Tomikawa J, Uenoyama Y, Ozawa M, Fukanuma T, Takase K, Goto T, Abe H, Ieda N, Minabe S, Deura C, Inoue N, Sanbo M, Tomita K, Hirabayashi M, Tanaka S, Imamura T, Okamura H, Maeda KI, Tsukamura H
Proc Natl Acad Sci USA 2012年
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Oestrogen-Dependent Suppression of Pulsatile Luteinizing Hormone Secretion and Kiss1 mRNA Expression in the Arcuate Nucleus During Late Lactation in Rats 査読有り
Yamada S, Uenoyama Y, Deura C, Minabe S, Naniwa Y, Iwata K, Kawata M, Maeda KI, Tsukamura H
J Neuroendocrinol 24 巻 頁： 1234-1242 2012年
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Different Critical Perinatal Periods and Hypothalamic Sites of Oestradiol Action in the Defeminization of LH Surge and Lordosis Capacity in the Rat
Sakakibara M, Deura C, Minabe S, Iwata Y, Uenoyama Y, Maeda KI, Tsukamura H
J Neuroendocrinol 2012年
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Kisspeptin neurons mediate reflex ovulation in the musk shrew (Suncus murinus)
Inoue N, Sasagawa K, Ikai K, Sasaki Y, Tomikawa J, Oishi S, Fujii N, Uenoyama Y, Ohmori Y, Yamamoto N, Hondo E, Maeda K and Tsukamura H
Proc Natl Acad Sci USA 108 巻 頁： 17527-32 2011年
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Central Injection of Ketone Body Suppresses Luteinizing Hormone Release via the Catecholaminergic Pathway in Female Rats
Iwata K, Kinoshita M, Susaki N, Uenoyama Y, Tsukamura H and Maeda KI
J Reprod Dev 57 巻 頁： 379-384 2011年
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Involvement of brain ketone bodies and the noradrenergic pathway in diabetic hyperphagia in rats. 招待有り 査読有り
Iwata K, Kinoshita M, Yamada S, Imamura T, Uenoyama Y, Tsukamura H and Maeda KI
J Physiol Sci 61 巻 頁： 103 - 113 2011年
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Ultrastructural evidence of kisspeptin-gonadotrophin-releasing hormone interaction in the median eminence of female rats: Implication of axo-axonal regulation of GnRH release 招待有り 査読有り
Uenoyama Y, Inoue N, Pheng V, Homma T, Takase K, Yamada S, Ajiki K, Ichikawa M, Okamura H, Maeda KI and Tsukamura H
J Neuroendocrinol 23 巻 頁： 863 - 870 2011年
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Testicular toxicity induced by a triple neurokinin receptor antagonist in male dogs 招待有り 査読有り
Noritake KI, Suzuki J, Matsuoka T, Makino T, Ohnishi H, Shimomura K, Uenoyama Y, Tsukamura H, Maeda KI and Sanbuissho A
Reprod Toxicol 31 巻 頁： 440 - 446 2011年
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Involvement of neurokinin receptors in the control of pulsatile luteinizing hormone secretion in rats 招待有り 査読有り
Noritake KI, Matsuoka T, Ohsawa T, Shimomura K, Sanbuissho A, Uenoyama Y, Maeda KI and Tsukamura H
J Reprod Dev 57 巻 頁： 409 - 415 2011年
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Analysis of pulsatile and surge-like luteinizing hormone secretion with frequent blood sampling in female mice 招待有り 査読有り
Minabe S, Uenoyama Y, Tsukamura H and Maeda KI
J Reprod Dev 57 巻 頁： 660 - 664 2011年
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Molecular characterization and estrogen regulation of hypothalamic Kiss1 gene in the pig 査読有り
Tomikawa J, Homma T, Tajima S, Shibata T, Inamoto Y, Takase K, Inoue N, Ohkura S, Uenoyama Y, Maeda KI and Tsukamura H
Biology of Reproduction 82 巻 頁： 313-319 2010年2月
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Activation of Neuropeptide FF Receptors by Kisspeptin Receptor Ligands 査読有り
Oishi S, Misu R, Tomita K, Setsuda S, Masuda R, Ohno H, Naniwa Y, Ieda N, Inoue N, Ohkura S, Uenoyama Y, Tsukamura H, Maeda K, Hirasawa A, Tsujimoto G, Fujii N
ACS Medicinal Chemistry Letters 頁： in press 2010年
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Neurobiological mechanisms underlying GnRH pulse generation by the hypothalamus 査読有り
Maeda KI, Ohkura S, Uenoyama Y, Wakabayashi Y, Oka Y, Tsukamura H, Okamura H
Brain Res 頁： in press 2010年
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Sexual differentiation of kisspeptin neurons responsible for sex difference in gonadotropin release in rats 招待有り 査読有り
Tsukamura H, Homma T, Tomikawa J, Uenoyama Y and Maeda K
Ann N Y Acad Sci 1200 巻 頁： 95 - 103 2010年
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Significance of Neonatal Testicular Sex Steroids to Defeminize Anteroventral Periventricular Kisspeptin Neurons and the GnRH/LH Surge System in Male Rats 査読有り
Homma T., Sakakibara M., Yamada S., Kinoshita M., Iwata K., Tomikawa J., Kanazawa T., Matsui H., Takatsu Y., Ohtaki T., Matsumoto H., Uenoyama Y., Maeda K.I, Tsukamura H.
Biology of Reproduction 81 巻 ( 6 ) 頁： 1216-25 2009年12月
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Potencies of Centrally- or Peripherally-Injected Full-Length Kisspeptin or Its C-Terminal Decapeptide on LH Release in Intact Male Rats 査読有り
Pheng V., Uenoyama Y., Homma T., Inamoto Y., Takase K., Yoshizawa-Kumagaye K., Isaka S., Watanabe T.X., Ohkura S., Tomikawa J., Maeda K.I., Tsukamura H.
Journal of Reproduction and Development 55 巻 頁： 378-382 2009年
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Physiological role of metastin/kisspeptin in regulating gonadotropin-releasing hormone (GnRH) secretion in female rats 査読有り
Ohkura, S.Uenoyama, Y.Yamada, S.Homma, T.Takase, K.Inoue, N.Maeda, K. I.Tsukamura, H.
Peptides 30 巻 頁： 49-56 2009年
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Food deprivation induces monocarboxylate transporter 2 expression in the brainstem of female rat 査読有り
Matsuyama, S.Ohkura, S.Iwata, K.Uenoyama, Y.Tsukamura, H.Maeda, K. I.Kimura, K.
J Reprod Dev 55 巻 頁： 256-261 2009年
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Kisspeptin/metastin: A key molecule controlling two modes of gonadotrophin-releasing hormone/luteinising hormone release in female rats
Uenoyama Y, Tsukamura H, Maeda KI
J Neuroendocrinol 21 巻 頁： 299 - 304 2009年
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Gonadotrophin-Releasing Hormone Pulse Generator Activity in the Hypothalamus of the Goat 査読有り
Ohkura S., Takase K., Matsuyama S., Mogi K., Ichimaru T., Wakabayashi Y., Uenoyama Y., Mori Y., Steiner R.A., Tsukamura H., Maeda K.I, Okamura H.
Journal of Neuroendocrinology 21 巻 頁： 813-821 2009年
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Possible role of oestrogen in pubertal increase of Kiss1/kisspeptin expression in discrete hypothalamic areas of female rats 査読有り
Takase K, Uenoyama Y, Inoue N, Matsui H, Yamada S, Shimizu M, Homma T, Tomikawa J, Kanda S, Matsumoto H, Oka Y, Tsukamura H, Maeda KI
Journal of Neuroendocrinology 21 巻 頁： 527-537 2009年
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Central lipoprivation-induced suppression of luteinizing hormone pulses is mediated by paraventricular catecholaminergic inputs in female rats 査読有り
Sajapitak S, Iwata K, Shahab M, Uenoyama Y, Yamada S, Kinoshita M, Bari FY, I'Anson H, Tsukamura H, Maeda K.
Endocrinology 149 巻 頁： 3016-24 2008年
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Paraventricular α1- and α2-adrenergic receptors mediate hindbrain lipoprivation-induced suppression of luteinizing hormone pulses in female rats
Sajapitak S, Uenoyama Y, Yamada S, Kinoshita M, Iwata K, Bari FY, I'Anson H, Tsukamula H, Maeda KI
J Reprod Dev 54 巻 頁： 198-202 2008年
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Oestrogen-dependent stimulation of luteinising hormone release by galanin-like peptide in female rats 査読有り
Uenoyama Y, Tsukamura H, Kinoshita M, Yamada S, Iwata K, Pheng V, Sajapitak S, Sakakibara M, Ohtaki T, Matsumoto H, Maeda KI
J Neuroendocrinol 20 巻 頁： 626-31 2008年
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Inhibition of Metastin (Kisspeptin-54)-GPR 54 Signaling in the Arcuate Nucleus-Median Eminence Region during Lactation in Rats. 査読有り
Yamada S, Uenoyama Y, Kinoshita M, Iwata K, Takase K, Matsui H, Adachi S, Inoue K, Maeda KI, Tsukamura H.
Endocrinology 148 巻 頁： 2226-2232 2007年
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Involvement of Anteroventral Periventricular Metastin/Kisspeptin Neurons in Estrogen Positive Feedback Action on Luteinizing Hormone Release in Female Rats
Adachi, S., Yamada, S., Takatsu, Y., Matsui, H., Kinoshita, M., Takase, K., Sugiura, H., Ohtaki, T., Matsumoto, H., Uenoyama, Y., Tsukamura, H., Inoue, K., and Maeda, K.
Journal of Reproduction and Development 53 巻 頁： 367-378 2007年
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Acute Lipoprivation Suppresses Pulsatile Luteinizing Hormone Secretion without Affecting Food Intake in Female Rats
Shahab,M., Sajapitak, S., Tsukamura H., Kinoshita M., Matsuyama S., Ohkura S., Yamada S., Uenoyama Y., I'Anson, H., and Maeda K.-I.
Journal of Reproduction and Development 52 巻 頁： 763-772 2006年
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Role of Noradrenergic Receptors in the Bed Nucleus of the Stria Terminalis in Regulating Pulsatile Leteinizing Hormone Secretion in Female Rats
Yamada, S., Uenoyama, Y., Maeda, K.-I., and Tsukamura, H.
Journal of Reproduction and Development 52 巻 頁： 115-121 2006年
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Involvement of central metastin in the regulation of preovulatory luteinizing hormone surge and estrous cyclicity in female rats
Kinoshita, M., Tsukamura, H., Adachi, S., Matsui, H., Uenoyama, Y., Iwata, K., Yamada, S., Inoue, K., Ohtaki, T., Matsumoto, H., and Maeda, K.-I.
Endocrinology 146 巻 頁： 4431-4436 2005年
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Involvement of brainstem catecholaminergic inputs to the hypothalamic paraventricular nucleus in estrogen receptorα expression in this nucleus during different stress conditions in female rats
Estacio, M., A., C., Tsukamura, H., Reyes, B., A., S., Uenoyama, Y., I'Anson, H. and Maeda, K.-I.
Endocrinology 145 巻 頁： 4917-4926 2004年
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The lipoxygenase pathway are involved in LH-stimulated progesterone production in bovine corpus luteum
Taniguchi, H., Uenoyama, Y., Miyamoto, Y. and Okuda, K
Prostaglandins and other lipid mediators 67 巻 頁： 49-60 2002年6月
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Prepubertal Changes in Immunoreactive Inhibin Concentration in Blood Serum and Testicular Tissue in Holstein Bull Calves
Matsuzaki S, Uenoyama Y, Okuda K, Watanabe G, Kitamura N, Taya K, Cruzana MBC, Yamada J
J Vet Med Sci 63 巻 頁： 1303-1307 2001年12月
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Estradiol-17b Is Produced in Bovine Corpus Luteum
Okuda K, Uenoyama Y, Berisha B, Lange IG, Taniguchi H, Kobayashi S, Kobayashi S-I, Miyamoto A, and Schams D
Biol Reprod 65 巻 頁： 1634-1639 2001年12月
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Age-related changes in the serum levels of inhibin, FSH, LH and testosterone in Holstein bulls. 査読有り
Matsuzaki S, Uenoyama Y, Okuda K, Watanabe G, Kitamura N, Taya K, Yamada J.
J Reprod Dev 46 巻 頁： 245-248 2000年8月
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Basic fibroblast growth factor-induced prostaglansin production and its intracellular mechanisms in cultured bovine luteal cells
Uenoyama Y, Murakami S, Schams D, Okuda K
J Reprod Dev 46 巻 頁： 93-99 2000年4月
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Luteinizing hormone receptors in the bovine corpus luteum during the oestrous cycle and pregnancy
Okuda K, Uenoyama Y, Naito C, Sakabe Y, Kawate N
Reprod Fertil Dev 11 巻 頁： 147-151 1999年11月
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Tumor necrosis factor a receptors in microvascular endothelial cells from bovine corpus luteum
Okuda K, Sakumoto R, Uenoyama Y, Berisha B, Miyamoto A, Schams D
Biol Reprod 61 巻 頁： 1017-1022 1999年10月
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Noradrenaline stimulates the secretion of prostaglandin F2a in cultured endometrial cells
Skarzynski DJ, Uenoyama Y, Kotwica J, Okuda K
Biol Reprod 60 巻 頁： 277-282 1999年2月
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Secretion of prostaglandins E2 and F2a by bovine endometrium in response to oxytocin during the estrous cycle
Miyamoto Y, Skarzynski DJ, Uenoyama Y, Okuda K
J Reprod Dev 44 巻 頁： 289-295 1998年8月
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Progesterone stimulation by prostaglandin F2a involves the protein kinase C pathway in cultured bovine luteal cells
Okuda K, Uenoyama Y, Lee KW, Sakumoto R, Skarzynski DJ
J Reprod Dev 44 巻 頁： 79-84 1998年4月
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Oxytocin receptors and their physiological significance in the ovary 招待有り
Okuda K, Uenoyama Y
Reproductive Biology Update -Novel Tools for Assessment of Environmental Toxicity- 頁： 297-304 1998年1月
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Up-regulation of oxytocin receptors in porcine endometrium by adenosine 3',5'-monophosphate
Uenoyama Y, Hattori S, Miyake M, Okuda K
Biol Reprod 57 巻 頁： 723-728 1997年10月
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Regulation of oxytocin receptors in bovine granulosa cells.
Uenoyama Y, Okuda K
Biol Reprod 57(3) 巻 頁： 569-574 1997年9月
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Functional oxytocin receptors in bovine granulosa cells
Okuda K, Uenoyama Y, Fujita Y, Iga K, Sakamoto K, Kimura T
Biol Reprod 56(3) 巻 頁： 625-631 1997年3月
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Effects of prostaglandins and oestradiol-17b on oxytocin binding in cultured bovine luteal cells
Okuda K, Uenoyama Y, Miyamoto A, Okano A, Schweigert FJ, Schams D.
Reprod Fertil Dev 7(5) 巻 頁： 1045-1051 1995年10月
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Epidermal growth factor and its receptor in bovine corpus luteum during the estrous cycle 査読有り
Okuda K, Uenoyama Y, Hwang KN, Yamada J, Wakabayashi K
J Reprod Dev 40 巻 頁： 349-54 1994年