Updated on 2025/06/28

写真a

 
ZHANG, Hedong
 
Organization
Graduate School of Informatics Department of Complex Systems Science 5 Professor
Graduate School
Graduate School of Informatics
Undergraduate School
School of Informatics Department of Natural Informatics
Title
Professor
Contact information
メールアドレス

Degree 1

  1. Doctor of Engineering ( 2002.3   Nagoya University ) 

Research Interests 8

  1. Healthcare

  2. IoT device

  3. Surface and Interfacial Properties

  4. Surface Engineering

  5. Thin Films

  6. Molecular Simulation

  7. Micro/Nano-scale Measurement

  8. Micro/Nano-tribology

Research Areas 6

  1. Others / Others  / Design Engineering/Machine Functional Elements/Tribology

  2. Others / Others  / Measurement Engineering

  3. Informatics / Computational science  / Molecular simulation

  4. Manufacturing Technology (Mechanical Engineering, Electrical and Electronic Engineering, Chemical Engineering) / Measurement engineering

  5. Manufacturing Technology (Mechanical Engineering, Electrical and Electronic Engineering, Chemical Engineering) / Machine elements and tribology

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Current Research Project and SDGs 5

  1. マルチスケールシミュレーション法の確立

  2. ナノすきま潤滑用の有機摩擦調整剤の分子設計論の確立

  3. ナノすきま潤滑の設計論の確立

  4. Establishment of technology for analyzing and evaluating health conditions based on measurement data

  5. Development of highly sensitive wearable sensors and devices

Research History 2

  1. Nagoya University   Graduate School of Informatics, Department of Complex Systems Science   Professor

    2021.9

  2. Nagoya University   Graduate School of Informatics, Department of Complex Systems Science   Associate Professor

    2017.4 - 2021.8

Education 2

  1. Nagoya University   Graduate School, Division of Engineering   Department of Electro-Mechanical Engineering

    1999.4 - 2002.3

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    Country: Japan

  2. Zhejiang University   Faculty of Engineering

    1990.9 - 1994.6

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    Country: Japan

Professional Memberships 4

  1. 日本機械学会

  2. 日本トライボロジー学会

  3. THE JAPAN SOCIETY OF MECHANICAL ENGINEERS

  4. JAPANESE SOCIETY OF TRIBOLOGISTS

Awards 14

  1. 分野融合研究優秀表彰

    2024.5   日本機械学会ロボティクス・メカトロニクス部門   ナノ深さ矩形流路を用いたナノインプリント用レジスト材料の濡れ現象の観測

    鈴木雅仁,伊藤伸太郎,福澤健二,東直輝,張賀東

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    Country:Japan

  2. 部門貢献表彰

    2023.3   日本機械学会情報・知能・精密機器部門  

    張賀東

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    Award type:Award from Japanese society, conference, symposium, etc. 

  3. 2022 Information, Intelligence and Precision Equipment Division Award for Young Engineer

    2023.3  

    Xingyu Chen

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    Award type:Award from Japanese society, conference, symposium, etc. 

  4. MIPE Student Award 2022

    2022.8   JSME and ASME  

    Xingyu Chen, Koya Inayoshi, Takumi Aoto, Hedong Zhang, Kenji Fukuzawa, Shintaro Itoh, Naoki Azuma

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    Award type:Award from international society, conference, symposium, etc. 

  5. MIPE AWARD 2015

    2015.6  

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    Country:Japan

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Papers 179

  1. Interfacial slip quantification in nanogaps using squeeze flow velocimetry

    Ozeki H., Azuma N., Fukuzawa K., Itoh S., Zhang H., Song Y.

    Physics of Fluids   Vol. 37 ( 5 )   2025.5

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    Publisher:Physics of Fluids  

    Understanding interfacial slip in nanogaps is crucial for modeling fluid flow in mechanical and analytical systems. To quantify slip length and shear stress at the liquid-solid interface, we measured the velocity of squeeze flow as fluid was pressed between solid surfaces. Our results showed that slip length varied with lateral positions and gap heights, while shear stress had a noticeable threshold beyond which slip begins, indicating the limiting shear stress model for interfacial slip in nanogaps. These insights enhance our understanding of interfacial slip phenomena in nanogaps and provide a foundation for modeling their influence on fluid flow.

    DOI: 10.1063/5.0271999

    Scopus

  2. Detection and Behaviors of TEMPO Derivatives in Seven Mass Spectrometry Ionization Methods Open Access

    Oyama, KI; Hor, S; Tsukamoto, M; Zhang, HD

    JOURNAL OF MASS SPECTROMETRY   Vol. 60 ( 4 ) page: e5122   2025.4

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    Language:English   Publisher:Journal of Mass Spectrometry  

    Four 2,2,6,6-tetramethylpiperidinyloxyl (TEMPO) derivatives with molecular weights of 339–1131 Da were synthesized to investigate their ionization behaviors in fast atom bombardment (FAB), electron ionization (EI), direct analysis in real time (DART), electrospray ionization (ESI), atmospheric pressure chemical ionization (APCI), atmospheric pressure photoionization (APPI), and matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS). These include 4-dodecanoylamino-2,2,6,6-tetramethyl-1-piperidinyloxy (1), 4-dodecylamino-2,2,6,6-tetramethyl-1-piperidinyloxy (2), N,N′-bis(2,2,6,6-tetramethyl-1-oxyl-4-piperidinyl)dodecanediamide (3), and bis-cholesterol TEMPO derivative 4. For TEMPO derivatives 1 and 2 (molecular weights: 353 Da and 339 Da), [M]+, [M+H]+•, and [M+2H]+ peaks were detected. TEMPO derivative 3, containing two TEMPO moieties, showed [M]+•, [M+H]+, [M+2H]+•, and [M+3H]+ peaks. EI was optimal for smaller derivatives, as molecular ion peaks were predominant. For larger analytes, molecular ion intensities weakened, favoring hydrogen adduct peaks. EI and DART-MS failed to detect bis-cholesterol TEMPO derivative 4. Under APCI and APPI-MS, N–O bond cleavage was observed. MALDI-MS detected only hydrogen adduct peaks. FAB, ESI, APCI, and APPI-MS detections varied with scan numbers, unlike EI, DART, and MALDI-MS.

    DOI: 10.1002/jms.5122

    Open Access

    Web of Science

    Scopus

    PubMed

  3. Bulk conformation and shear-induced transitions in bottlebrush poly(alkyl methacrylate): The role of side chain length and polymer flexibility Reviewed

    Himanshu Shekhar, Yuma Chikazawa, Yuxi Song, Hedong Zhang

    Tribology International   Vol. 204   page: 110476 - 110476   2025.4

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:Elsevier BV  

    DOI: 10.1016/j.triboint.2024.110476

    Web of Science

    Scopus

  4. Wearable PZT Piezoelectric Sensor Device for Accurate Arterial Pressure Pulse Waveform Measurement Reviewed

    Li, MY; Aoyama, J; Inayoshi, K; Zhang, HD

    ADVANCED ELECTRONIC MATERIALS     2025.1

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/aelm.202400852

    Web of Science

    Scopus

  5. Stretching and immobilizing a single DNA molecule on a glass surface using pressure flow in a microchannel for super-resolution imaging Open Access

    Naoki Azuma, Ryotaro Suzuki, Kenji Fukuzawa, Shintaro Itoh, Hedong Zhang

    AIP Advances   Vol. 15 ( 1 )   2025.1

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    Publishing type:Research paper (scientific journal)   Publisher:AIP Publishing  

    Single-DNA analysis combines fluorescence microscopy with a method of stretching a single DNA molecule from its random coil shape to a linear shape. Although super-resolution imaging methods can be used for analyzing the DNA with a higher lateral resolution, these methods require several seconds to minutes to obtain a super-resolution image of the entire DNA molecule. Therefore, immobilizing the stretched DNA molecules on the substrate surface is essential for preventing the decrease in the lateral resolution caused by thermal fluctuations of the molecule. Previous studies utilized a method to use super-resolution imaging methods, in which a DNA molecule can be stretched by the surface tension of the air–liquid interface and immobilized on a glass surface treated with a silane coupling agent. However, achieving control over the stretch ratio of the DNA molecule poses challenges because of the difficulty in accurately adjusting the surface tension. In this study, we used the combination of stretching DNA molecules using pressure flow in a microchannel and immobilizing them on a glass surface treated with a silane coupling agent. Our results indicated that this method enabled the control of the stretch ratio of the molecule by adjusting the flow velocity and the super-resolution imaging while reducing thermal fluctuation by immobilizing the molecule on the surface. Combining the method with the super-resolution imaging method enables the analysis of single DNA molecules with higher accuracy.

    DOI: 10.1063/5.0223375

    Open Access

    Web of Science

    Scopus

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MISC 1

  1. Formation mechanism and conformation of polyalkylmethacrylate (PAMA) polymer adsorbed film from lubricant oil

    SONG Yuxi, FUKUZAWA Kenji, ITOH Shintaro, ZHANG Hedong, AZUMA Naoki

    日本トライボロジー学会トライボロジー会議予稿集(CD-ROM)   Vol. 2021   2021

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Presentations 486

  1. トライボシミュレーションの進歩と活用 Invited

    張賀東

    分子研研究会「トライボロジーの分子科学」  2025.4.7 

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    Event date: 2025.4

    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Venue:岡崎コンファレンスセンター   Country:Japan  

  2. 熱アシスト磁気記録におけるDLC表面上のPFPE膜のメカノケミカル分解に関するReaxFF分子動力学解析

    情報・知能・精密機器部門講演会 (IIP2025)   2025.3.4  日本機械学会情報・知能・精密機器部門

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    Event date: 2025.3

    Language:English   Presentation type:Oral presentation (general)  

    Venue:山口大学 常盤キャンパス  

  3. 接触させた球面と平面間のナノすきまを用いた環状DNAの一分子伸長と長さ判別

    佐藤鐘太, 東直輝, 福澤健二, 伊藤伸太郎, 張賀東, 宋玉玺

    情報・知能・精密機器部門講演会 (IIP2025)   2025.3.3  日本機械学会情報・知能・精密機器部門

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    Event date: 2025.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:山口大学 常盤キャンパス  

  4. ハンセン溶解度パラメータを用いたポリメチルメタクリレート薄膜の固体面への吸着特性測定

    福井隆士, 伊藤伸太郎, 福澤健二, 東直輝, 張賀東

    情報・知能・精密機器部門講演会 (IIP2025)   2025.3.3  日本機械学会情報・知能・精密機器部門

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    Event date: 2025.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:山口大学 常盤キャンパス  

  5. フレキシブルPZT圧電センサを用いた非侵襲・高感度の圧脈波計測ウェアラブルデバイスの開発

    李旻玉, 青山純, 斎藤まどか,張賀東

    情報・知能・精密機器部門講演会 (IIP2025)   2025.3.3  日本機械学会情報・知能・精密機器部門

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    Event date: 2025.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:山口大学 常盤キャンパス  

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Research Project for Joint Research, Competitive Funding, etc. 10

  1. カフレス血圧・血糖の非侵襲・高精度計測用ウェアラブルデバイスの事業化検証

    2024.6 - 2025.3

    令和5(2023)年度 大学発新産業創出基金事業 スタートアップ・エコシステム共創プログラム GAPファンドプログラム『ステップ1』 

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    Grant amount:\6500000 ( Direct Cost: \5000000 、 Indirect Cost:\1500000 )

  2. 大規模分子シミュレーションと先端計測の協働による有機摩擦調整剤の分子設計指針の構築

    2021.3 - 2023.2

    メカトロニクス技術高度化研究助成 

    張 賀東

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    Authorship:Principal investigator 

    Grant amount:\2000000

  3. 高性能マスクのフィルタ機能を簡便に実現するナノ繊維網目構造体スプレーの開発

    2020.12 - 2022.12

    豊秋奨学会2020年度研究助成 

    張 賀東

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    Authorship:Principal investigator 

    Grant amount:\750000

  4. Reversed-hierarchical multiscale analytical approach to elucidate micro-contacts separated by liquid nano-film

    2020.6 - 2021.6

    Taiho Kogyo Tribology Research Foundation, Research and Development Grant 

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    Authorship:Coinvestigator(s) 

  5. 環境調和型の新規な有機摩擦調整剤の開発

    2019.11 - 2020.11

    研究成果最適展開支援プログラム A-STEP機能検証フェーズ 試験研究タイプ 

    塚本眞幸

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    Grant type:Competitive

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KAKENHI (Grants-in-Aid for Scientific Research) 12

  1. Optimal Molecular Design of Polymeric Organic Friction Modifiers: A Computational Scheme Linking Molecular Structure to Macroscopic Frictional Properties

    Grant number:24H00282  2024.4 - 2028.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (A)

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\48230000 ( Direct Cost: \37100000 、 Indirect Cost:\11130000 )

  2. Science for Boundary Lubrication - Essence of Low Friction Mechanism Based on Structure and Dynamics of Additive Adsorption Layer

    Grant number:23H05448  2023.4 - 2028.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (S)

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    Authorship:Coinvestigator(s)  Grant type:Competitive

    Grant amount:\20930000 ( Direct Cost: \16100000 、 Indirect Cost:\4830000 )

  3. 境界潤滑層の構造とダイナミクス-低摩擦をもたらす潤滑油分子の最適設計

    Grant number:23H00158  2023.4 - 2026.3

    日本学術振興会  科学研究費助成事業  基盤研究(A)

    平山 朋子, 富永 大輝, 土屋 智由, 日野 正裕, 張 賀東, 富永 大輝, 土屋 智由, 日野 正裕, 張 賀東

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    Authorship:Coinvestigator(s) 

    本研究では、潤滑油中に含まれる添加剤の表面吸着に由来する『境界潤滑層』に焦点を当て、その摩擦係数の予測と更なる超低摩擦化に向けた潤滑油の最適設計指針の提示を目指す。具体的には、境界潤滑層の素となる性状を基油中でのその『構造』と『ダイナミクス』に求め、中性子線を用いた各種分析を実施することでそれらの値を定量的に抽出する。さらに得られた構造・ダイナミクス情報と「点」接触系および「面」接触系における『原理的な境界潤滑摩擦係数』を分子シミュレーションを援用して紐付けることにより、超低摩擦発現に向けた境界潤滑の本質を明らかにすることを目的とする。
    本研究では、潤滑油中に含まれる添加剤の表面吸着に由来する『境界潤滑層』に焦点を当て、その摩擦係数の予測と更なる超低摩擦化に向けた潤滑油の最適設計指針の提示を目指すものである。本研究実施期間において、点接触系であるコロイドプローブAFM摩擦試験の条件出しを行い、安定した境界潤滑摩擦係数を取得する手法を確立した。
    令和5年度が最終年度であるため、記入しない。
    令和5年度が最終年度であるため、記入しない。

  4. Precise Molecular Design of Organic Friction Modifiers by Large-Scale Molecular Simulations, Advanced Measurements, and Chemical Syntheses

    Grant number:21H01238  2021.4 - 2024.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)

    Zhang Hedong

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\17940000 ( Direct Cost: \13800000 、 Indirect Cost:\4140000 )

    Aiming to establish systematic molecular design guidelines for organic friction modifiers (OFMs), we advanced our research through the collaboration of large-scale molecular simulations, advanced measurements, and chemical synthesis. Specifically, we established large-scale molecular simulation methods and measurement techniques that can verify and complement the simulation results. Additionally, we designed and synthesized new OFM molecules. Based on these foundations, we tackled the hierarchical correlation between the nano- to macro-scale characteristics of lubrication systems containing OFMs with different molecular structures. These characteristics included the nano-scale characteristics of OFM molecules, the micro-scale characteristics of OFM adsorption films, and the macro-scale friction and wear properties of the system.

  5. Creation of High-Performance Organic Friction Modifiers for Green Tribology

    Grant number:19K21915  2019.6 - 2022.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Challenging Research (Exploratory)

    Zhang Hedong

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    Authorship:Principal investigator 

    Grant amount:\6370000 ( Direct Cost: \4900000 、 Indirect Cost:\1470000 )

    To create high-performance organic friction modifiers (OFM), we designed and synthesized more than 10 types of TEMPO-based molecules, which include a cyclic structure with a free radical at the end of hydrocarbon chains, by changing the functional groups that connect the hydrocarbon chains to the cyclic structure and the length, number, and degree of unsaturation of the hydrocarbon chains. We gained and accumulated knowledge on the relationship between molecular structures of OFMs and their friction and wear properties. Moreover, we successfully developed a new OFM that exhibits lower friction coefficients even under highly-loaded and prolonged sliding and higher anti-wear performance than conventional OFMs.

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Industrial property rights 3

  1. 押し付け用装置および血圧測定装置

    張賀東,李旻玉,三矢保永

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    Applicant:名古屋大学

    Application no:特願2024-207023  Date applied:2024.11

  2. 圧力センサ用パッドおよび圧力測定装置

    張賀東,李旻玉

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    Applicant:国立大学法人東海国立大学機構

    Application no:2024-028019  Date applied:2024.2

    Patent/Registration no:C20230347JP#P01 

  3. 有機摩擦調整剤

    塚本眞幸, 張賀東

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    Application no:特願2020-009894  Date applied:2020.1

    Country of applicant:Domestic  

 

Teaching Experience (On-campus) 12

  1. 化学実験

    2016

  2. 機能性表面科学特論

    2016

  3. 化学実験

    2015

  4. 機能性表面科学特論

    2015

  5. 機能性表面科学特論

    2014

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