論文 - 小杉 智規
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High fat and high sucrose (western) diet induce steatohepatitis that is dependent on fructokinase. 査読有り
Ishimoto T, Lanaspa MA, Rivard CJ, Roncal-Jimenez CA, Orlicky DJ, Cicerchi C, McMahan RH, Abdelmalek MF, Rosen HR, Jackman MR, Maclean PS, Diggle CP, Asipu A, Inaba S, Kosugi T, Sato W, Maruyama S, Sánchez-Lozada LG, Sautin YY, Hill JO, Bonthron DT, Johnson RJ.
Hepatology 2013年6月
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Endogenous fructose production and metabolism in the liver contributes to the development of metabolic syndrome. 査読有り
Lanaspa MA, Ishimoto T, Li N, Cicerchi C, Orlicky DJ, Ruzicky P, Rivard C, Inaba S, Roncal-Jimenez CA, Bales ES, Diggle CP, Asipu A, Petrash JM, Kosugi T, Maruyama S, Sanchez-Lozada LG, McManaman JL, Bonthron DT, Sautin YY, Johnson RJ.
Nat Commun. ( 4 ) 頁： 2434 2013年
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Uncoupling of VEGF with endothelial NO as a potential mechanism for abnormal angiogenesis in the diabetic nephropathy. 査読有り
Nakagawa T, Sato W, Kosugi T, Johnson RJ.
J Diabetes Res. 2013年
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Toll-like receptor 3 ligand, polyIC, induces proteinuria and glomerular CD80, and increases urinary CD80 in mice. 査読有り
Ishimoto T, Shimada M, Gabriela G, Kosugi T, Sato W, Lee PY, Lanaspa MA, Rivard C, Maruyama S, Garin EH, Johnson RJ
Nephrol Dial Transplant. 2012年12月
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Deficiency of Growth Factor Midkine Exacerbates Necrotizing Glomerular Injuries in Progressive Glomerulonephritis. 査読有り
Kojima H, Kosugi T, Sato W, Sato Y, Maeda K, Kato N, Kato K, Inaba S, Ishimoto T, Tsuboi N, Matsuo S, Maruyama S, Yuzawa Y, Kadomatsu K.
Am J Pathol. 2012年11月
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Distribution of hydrogen sulfide (H(2)S)-producing enzymes and the roles of the H(2)S donor sodium hydrosulfide in diabetic nephropathy. 査読有り
Yamamoto J, Sato W, Kosugi T, Yamamoto T, Kimura T, Taniguchi S, Kojima H, Maruyama S, Imai E, Matsuo S, Yuzawa Y, Niki I.
Clin Exp Nephrol. 2012年8月
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A rare case of acute kidney injury associated with autoimmune hemolytic anemia and thrombocytopenia after long-term usage of oxaliplatin. 査読有り
Ito I, Ito Y, Mizuno M, Suzuki Y, Yasuda K, Ozaki T, Kosugi T, Yasuda Y, Sato W, Tsuboi N, Maruyama S, Imai E, Matsuo S.
Clin Exp Nephrol. 16 巻 ( 3 ) 頁： 490-494 2012年6月
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Opposing effects of fructokinase C and A isoforms on fructose-induced metabolic syndrome in mice. 査読有り
Ishimoto T, Lanaspa MA, Le MT, Garcia GE, Diggle CP, Maclean PS, Jackman MR, Asipu A, Roncal-Jimenez CA, Kosugi T, Rivard CJ, Maruyama S, Rodriguez-Iturbe B, Sanchez-Lozada LG, Bonthron DT, Sautin YY, Johnson RJ
Proc Natl Acad Sci U S A. 109 巻 ( 11 ) 頁： 4320-4325 2012年3月
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Midkine and the kidney; health and diseases 招待有り 査読有り
Kosugi T and Sato W
Nephrol. Dial Transplant. 2011年12月
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Selective Stimulation of VEGFR2 Accelerates Progressive Renal Disease. 査読有り
Sato W, Tanabe K, Kosugi T, Hudkins K, Lanaspa MA, Zhang L, Campbell-Thompson M, Li Q, Long DA, Alpers CE, Nakagawa T.
American Journal of Pathology 2011年5月
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Growth factor Midkine is involved in the pathogenesis of renal injury induced by protein overload containing endotoxin. 査読有り
Kato K, Kosugi T, Sato W, Arata-Kawai H, Ozaki T, Tsuboi N, Ito I, Tawada H, Yuzawa Y, Matsuo S, Kadomatsu K, Maruyama S.
Clin Exp Nephrol. 2011年3月
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Basigin/CD147 promotes renal fibrosis after unilateral ureteral obstruction. 査読有り
Kato N, Kosugi T, Sato W, Ishimoto T, Kojima H, Sato Y, Sakamoto K, Maruyama S, Yuzawa Y, Matsuo S, Kadomatsu K.
American Journal of Pathology. 178 巻 ( 2 ) 頁： 572-9 2011年2月
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Endothelial dysfunction as a potential contributor in diabetic nephropathy. 査読有り
Nakagawa T, Tanabe K, Croker BP, Johnson RJ, Grant MB, Kosugi T, Li Q.
Nature Review Nephrology. 7 巻 ( 1 ) 頁： 36-44 2011年1月
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Endothelial von Willebrand factor release due to eNOS deficiency predisposes to thrombotic microangiopathy in mouse aging kidney. 査読有り
Nakayama T, Sato W, Yoshimura A, Zhang L, Kosugi T, Campbell-Thompson M, Kojima H, Croker BP, Nakagawa T.
American Journal of Pathology. 176 巻 ( 5 ) 頁： 2198-208 2010年5月
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Soluble Flt-1 gene therapy ameliorates albuminuria but accelerates tubulointerstitial injury in diabetic mice. 査読有り
Kosugi T, Nakayama T, Li Q, Chiodo VA, Zhang L, Campbell-Thompson M, Grant M, Croker BP, Nakagawa T.
Am J Physiol Renal Physiol. 298 巻 ( 3 ) 頁： F609-616 2010年3月
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Dietary fructose causes tubulointerstitial injury in the normal rat kidney. 査読有り
Nakayama T, Kosugi T, Gersch M, Connor T, Sanchez-Lozada LG, Lanaspa MA, Roncal C, Perez-Pozo SE, Johnson RJ, Nakagawa T.
Am J Physiol Renal Physiol. 298 巻 ( 3 ) 頁： F712-20 2010年3月
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eNOS knockout mice with advanced diabetic nephropathy have less benefit from renin-angiotensin blockade than from aldosterone receptor antagonists. 査読有り
Kosugi T, Heinig M, Nakayama T, Matsuo S, Nakagawa T.
American Journal of Pathology 176 巻 ( 2 ) 頁： 619-629 2010年2月
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Effect of lowering uric acid on renal disease in the type 2 diabetic db/db mice. 査読有り
Kosugi T, Nakayama T, Heinig M, Zhang L, Yuzawa Y, Sanchez-Lozada LG, Roncal C, Johnson RJ, Nakagawa T.
Am J Physiol Renal Physiol. 297 巻 ( 2 ) 頁： F481-488 2009年8月
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The E-selectin ligand basigin/CD147 is responsible for neutrophil recruitment in renal ischemia/reperfusion 査読有り
Kato N, Yuzawa Y, Kosugi T, Hobo A, Sato W, Miwa Y, Sakamoto K, Matsuo S, Kadomatsu K.
Journal of American Society of Nephrology 20 巻 ( 7 ) 頁： 1565-1576 2009年7月
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Abnormal angiogenesis in diabetic nephropathy. 査読有り
Nakagawa T, Kosugi T, Haneda M, Rivard CJ, Long DA.
Diabetes. 58 巻 ( 7 ) 頁： 1471-8 2009年7月