Updated on 2022/04/12

写真a

 
KAWASHIMA, Hiroki
 
Organization
Graduate School of Medicine Program in Integrated Medicine Internal Medicine Professor
Graduate School
Graduate School of Medicine
Undergraduate School
School of Medicine Department of Medicine
Title
Professor
Contact information
メールアドレス

Degree 1

  1. 医学博士 ( 2005.10   名古屋大学 ) 

Research Interests 1

  1. 胆膵疾患の内視鏡的診断と治療

Research Areas 1

  1. Others / Others  / Digestive Organs Internal Medicine

Education 1

  1. Nagoya University   Faculty of Medicine

    1989.4 - 1995.3

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    Country: Japan

Professional Memberships 8

  1. 日本内科学会

  2. 日本消化器病学会   学会評議員

  3. 日本消化器内視鏡学会   学術評議委員

  4. 日本超音波医学会   代議員

  5. 日本膵臓学会

  6. 日本胆道学会   評議員 学術委員

  7. 日本癌治療学会

  8. 日本消化器がん検診学会

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Committee Memberships 4

  1. 日本肝胆膵外科学会   胆道癌診療ガイドライン委員  

    2020.8   

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    Committee type:Other

  2. 日本消化器内視鏡学会   内視鏡的乳頭切除術診療ガイドライン作成委員  

    2019.7 - 2021.3   

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    Committee type:Other

  3. 日本胆道学会   会則検討委員  

    2018.9   

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    Committee type:Academic society

  4. 日本胆道学会   学術委員  

    2016.9   

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    Committee type:Academic society

Awards 1

  1. 内科学会奨励賞

    2020.4   日本内科学会   切除不能遠位胆道悪性狭窄に対するFully-covered Self-Expandable Metal Stentsの外径別多施設前向き比較試験

    川嶋啓揮

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    Award type:Award from Japanese society, conference, symposium, etc.  Country:Japan

 

Papers 261

  1. Endoscopic papillectomy for ampullary adenoma and early adenocarcinoma: Analysis of factors related to treatment outcome and long-term prognosis Reviewed International journal

    Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Iida Tadashi, Tanaka Hiroyuki, Furukawa Kazuhiro, Nakamura Masanao, Honda Takashi, Hashimoto Senju, Itoh Akihiro, Ishigami Masatoshi, Hirooka Yoshiki, Fujishiro Mitsuhiro

    DIGESTIVE ENDOSCOPY   Vol. 33 ( 5 ) page: 858 - 869   2021.7

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/den.13881

    Web of Science

    PubMed

  2. Comparison of 8-and 10-mm diameter fully covered self-expandable metal stents: A multicenter prospective study in patients with distal malignant biliary obstruction Reviewed International journal

    Kawashima Hiroki, Hashimoto Senju, Ohno Eizaburo, Ishikawa Takuya, Morishima Tomomasa, Matsubara Hiroshi, Sugimoto Hiroyuki, Nonogaki Koji, Kanamori Akira, Hara Kazuo, Kuwahara Takamichi, Nakamura Masanao, Miyahara Ryoji, Ishigami Masatoshi, Ando Masahiko, Hirooka Yoshiki

    DIGESTIVE ENDOSCOPY   Vol. 31 ( 4 ) page: 439 - 447   2019.7

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/den.13366

    Web of Science

    PubMed

  3. Comprehensive immunotherapy combined with intratumoral injection of zoledronate-pulsed dendritic cells, intravenous adoptive activated T lymphocyte and gemcitabine in unresectable locally advanced pancreatic carcinoma: a phase I/II trial Invited Reviewed International journal

    Hirooka Yoshiki, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Kamigaki Takashi, Goto Shigenori, Takahara Masashi, Goto Hidemi

    ONCOTARGET   Vol. 9 ( 2 ) page: 2838 - 2847   2018.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.18632/oncotarget.22974

    Web of Science

    PubMed

  4. Correction to: Clinical guidelines for primary sclerosing cholangitis 2017.

    Isayama H, Tazuma S, Kokudo N, Tanaka A, Tsuyuguchi T, Nakazawa T, Notohara K, Mizuno S, Akamatsu N, Serikawa M, Naitoh I, Hirooka Y, Wakai T, Itoi T, Ebata T, Okaniwa S, Kamisawa T, Kawashima H, Kanno A, Kubota K, Tabata M, Unno M, Takikawa H, PSC guideline committee Members: Ministry of Health, Labour and Welfare (Japan) Research Project, The Intractable Hepatobiliary Disease Study Group.

    Journal of gastroenterology     2022.3

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    Language:English  

    DOI: 10.1007/s00535-022-01867-7

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  5. Utility of endoscopic retrograde cholangiopancreatography in management of pediatric pancreaticobiliary disease.

    Makita S, Amano H, Kawashima H, Hinoki A, Shirota C, Tainaka T, Sumida W, Yokota K, Okamoto M, Takimoto A, Yasui A, Nakagawa Y, Uchida H

    BMC pediatrics   Vol. 22 ( 1 ) page: 134   2022.3

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    Language:English  

    DOI: 10.1186/s12887-022-03207-3

    PubMed

  6. Patients with low muscle mass have characteristic microbiome with low potential for amino acid synthesis in chronic liver disease.

    Yamamoto K, Ishizu Y, Honda T, Ito T, Imai N, Nakamura M, Kawashima H, Kitaura Y, Ishigami M, Fujishiro M

    Scientific reports   Vol. 12 ( 1 ) page: 3674   2022.3

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    Language:English  

    DOI: 10.1038/s41598-022-07810-3

    PubMed

  7. Changes in the gut microbiome in relation to the degree of gastric mucosal atrophy before and after Helicobacter pylori eradication

    Furune Satoshi, Yamamoto Kenta, Honda Takashi, Fujiyoshi Toshihisa, Kakushima Naomi, Furukawa Kazuhiro, Ohno Eizaburo, Nakamura Masanao, Miyahara Ryoji, Kawashima Hiroki, Ishigami Masatoshi, Hirooka Yoshiki, Fujishiro Mitsuhiro

    SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY   Vol. 57 ( 3 ) page: 266 - 273   2022.3

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  8. Results of a Phase II Study on the use of Neoadjuvant Chemotherapy (FOLFIRINOX or Gemcitabine with nab-paclitaxel) for Borderline-Resectable Pancreatic Cancer (NUPAT-01).

    Yamaguchi J, Yokoyama Y, Fujii T, Yamada S, Takami H, Kawashima H, Ohno E, Ishikawa T, Maeda O, Ogawa H, Kodera Y, Nagino M, Ebata T

    Annals of surgery     2022.3

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    Language:English  

    DOI: 10.1097/SLA.0000000000005430

    PubMed

  9. Artificial intelligence-based diagnosis of upper gastrointestinal subepithelial lesions on endoscopic ultrasonography images

    Hirai Keiko, Kuwahara Takamichi, Furukawa Kazuhiro, Kakushima Naomi, Furune Satoshi, Yamamoto Hideko, Marukawa Takahiro, Asai Hiromitsu, Matsui Kenichi, Sasaki Yoji, Sakai Daisuke, Yamada Koji, Nishikawa Takahiro, Hayashi Daijuro, Obayashi Tomohiko, Komiyama Takuma, Ishikawa Eri, Sawada Tsunaki, Maeda Keiko, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Ishigami Masatoshi, Fujishiro Mitsuhiro

    GASTRIC CANCER   Vol. 25 ( 2 ) page: 382 - 391   2022.3

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  10. The impact of the age-adjusted Charlson comorbidity index as a prognostic factor for endoscopic papillectomy in ampullary tumors

    Takada Yoshihisa, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Mizutani Yasuyuki, Iida Tadashi, Yamamura Takeshi, Kakushima Naomi, Furukawa Kazuhiro, Nakamura Masanao, Honda Takashi, Ishigami Masatoshi, Ito Akihiro, Hirooka Yoshiki

    JOURNAL OF GASTROENTEROLOGY   Vol. 57 ( 3 ) page: 199 - 207   2022.3

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  11. Clinical practice guidelines for endoscopic papillectomy.

    Itoi T, Ryozawa S, Katanuma A, Kawashima H, Iwasaki E, Hashimoto S, Yamamoto K, Ueki T, Igarashi Y, Inui K, Fujita N, Fujimoto K

    Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society   Vol. 34 ( 3 ) page: 394 - 411   2022.3

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    Language:English  

    DOI: 10.1111/den.14233

    PubMed

  12. Safety and efficacy of MIKE-1 in patients with advanced pancreatic cancer: a study protocol for an open-label phase I/II investigator-initiated clinical trial based on a drug repositioning approach that reprograms the tumour stroma

    Mizutani Yasuyuki, Iida Tadashi, Ohno Eizaburo, Ishikawa Takuya, Kinoshita Fumie, Kuwatsuka Yachiyo, Imai Miwa, Shimizu Shinobu, Tsuruta Toshihisa, Enomoto Atsushi, Kawashima Hiroki, Fujishiro Mitsuhiro

    BMC CANCER   Vol. 22 ( 1 ) page: 205   2022.2

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  13. Effects of steroid use for stenosis prevention after endoscopic submucosal dissection for cervical esophageal cancer

    Muroi Koichi, Kakushima Naomi, Furukawa Kazuhiro, Furune Satoshi, Ito Nobuhito, Hirose Takashi, Ishikawa Eri, Mizutani Yasuyuki, Sawada Tsunaki, Maeda Keiko, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Funasaka Kohei, Miyahara Ryoji, Fujishiro Mitsuhiro

    INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY     2022.2

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  14. Preliminary Comparison of Endoscopic Brush and Net Catheters as the Sampling Tool to Analyze the Intestinal Mucus in the Rectum with Ulcerative Colitis Patients

    Nakamura Masanao, Maeda Keiko, Yamamoto Kenta, Yamamura Takeshi, Sawada Tsunaki, Ishikawa Eri, Kakushima Naomi, Furukawa Kazuhiro, Iida Tadashi, Mizutani Yasuyuki, Ishikawa Takuya, Ohno Eizaburo, Honda Takashi, Ishigami Masatoshi, Kawashima Hiroki

    DIGESTION     page: 1 - 12   2022.2

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  15. Immunoproliferative Small Intestinal Disease Diagnosed by Double-balloon Endoscopy with Biopsy Sampling.

    Meza MRR, Nakamura M, Yamamura T, Maeda K, Sawada T, Ishikawa E, Kakushima N, Furukawa K, Ohno E, Honda T, Kawashima H, Ishigami M

    Internal medicine (Tokyo, Japan)     2022.2

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    Language:English  

    DOI: 10.2169/internalmedicine.8847-21

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  16. Immune-related Liver Injury is a Poor Prognostic Factor in Patients with Nonsmall Cell Lung Cancer Treated with Immune Checkpoint Inhibitors

    Yamamoto Takafumi, Ito Takanori, Hase Tetsunari, Ishigami Masatoshi, Mizuno Kazuyuki, Yamamoto Kenta, Imai Norihiro, Ishizu Yoji, Honda Takashi, Shibata Hirofumi, Hatta Takahiro, Yogo Naoyuki, Yasuda Satoshi, Toyoda Hidenori, Abe Takashi, Kawashima Hiroki, Hashimoto Naozumi, Fujishiro Mitsuhiro

    CANCER INVESTIGATION   Vol. 40 ( 2 ) page: 189 - 198   2022.2

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  17. Factors related to delayed adverse events of endoscopic submucosal dissection in the duodenum.

    Kawamura T, Hirose T, Kakushima N, Furukawa K, Furune S, Ishikawa E, Sawada T, Maeda K, Yamamura T, Ishikawa T, Ohno E, Nakamura M, Honda T, Ishigami M, Kawashima H, Fujishiro M

    Digestive diseases (Basel, Switzerland)     2022.2

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    Language:English  

    DOI: 10.1159/000522362

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  18. Development of a Novel Evaluation Method for Endoscopic Ultrasound-Guided Fine-Needle Biopsy in Pancreatic Diseases Using Artificial Intelligence

    Ishikawa Takuya, Hayakawa Masato, Suzuki Hirotaka, Ohno Eizaburo, Mizutani Yasuyuki, Iida Tadashi, Fujishiro Mitsuhiro, Kawashima Hiroki, Hotta Kazuhiro

    DIAGNOSTICS   Vol. 12 ( 2 )   2022.2

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  19. Initial experience of tofacitinib for treating refractory moderate-to-severe ulcerative colitis

    Nakamura Masanao, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Eri, Ishikawa Takuya, Kakushima Naomi, Furukawa Kazuhiro, Ohno Eizaburo, Kawashima Hiroki, Honda Takashi, Ishigami Masatoshi, Fujishiro Mitsuhiro

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 84 ( 1 ) page: 169 - 179   2022.2

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    Language:Japanese  

    DOI: 10.18999/nagjms.84.1.169

    Web of Science

  20. Comparison of outcomes between secondary fully covered and uncovered self-expandable metal stents in the treatment of recurrent biliary obstruction of pancreatic cancer

    Kataoka Kunio, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Mizutani Yasuyuki, Iida Tadashi, Furukawa Kazuhiro, Nakamura Masanao, Honda Takashi, Ishigami Masatoshi, Fujishiro Mitsuhiro

    SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES     2022.1

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  21. Relationship between psoas muscle index and long-term survival in older patients aged >= 80 years after endoscopic submucosal dissection for gastric cancer

    Ito Nobuhito, Funasaka Kohei, Miyahara Ryoji, Furukawa Kazuhiro, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Hirooka Yoshiki, Fujishiro Mitsuhiro

    INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY     2022.1

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  22. Current status of the diagnosis of chronic pancreatitis by ultrasonographic elastography

    Nakaoka Kazunori, Hashimoto Senju, Miyahara Ryoji, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Kuwahara Takamichi, Tanaka Hiroyuki, Hirooka Yoshiki

    KOREAN JOURNAL OF INTERNAL MEDICINE   Vol. 37 ( 1 ) page: 27 - 36   2022.1

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  23. Fish bone migration after pancreaticoduodenectomy: Incidence and treatment options

    Takada Yoshihisa, Ishikawa Takuya, Kawashima Hiroki, Mizutani Yasuyuki, Ohno Eisaburo, Iida Tadashi, Ogawa Hiroshi, Hayashi Masamichi, Takami Hideki, Onoe Shunsuke, Ishigami Masatoshi

    JOURNAL OF DIGESTIVE DISEASES   Vol. 23 ( 1 ) page: 44 - 49   2022.1

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  24. Feasibility of endoscopic ultrasonography using a 60-MHz ultrasound miniature probe in the upper gastrointestinal tract

    Asai Hiromitsu, Furukawa Kazuhiro, Miyahara Ryoji, Funasaka Kohei, Furune Satoshi, Nakamura Masanao, Kawashima Hiroki, Ishigami Masatoshi, Hirooka Yoshiki, Fujishiro Mitsuhiro

    JOURNAL OF MEDICAL ULTRASONICS   Vol. 49 ( 1 ) page: 61 - 69   2022.1

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  25. Differentiation Between Solid Pseudopapillary Neoplasm of the Pancreas and Nonfunctional Pancreatic Neuroendocrine Neoplasm Using Endoscopic Ultrasound

    Kataoka Kunio, Ishikawa Takuya, Ohno Eizaburo, Mizutani Yasuyuki, Iida Tadashi, Furukawa Kazuhiro, Nakamura Masanao, Honda Takashi, Ishigami Masatoshi, Kawashima Hiroki, Hirooka Yoshiki, Fujishiro Mitsuhiro

    PANCREAS   Vol. 51 ( 1 ) page: 106 - 111   2022.1

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  26. Usefulness of Macroscopic On-Site Evaluation Using a Stereomicroscope during EUS-FNB for Diagnosing Solid Pancreatic Lesions.

    Ishikawa T, Ohno E, Mizutani Y, Iida T, Uetsuki K, Yashika J, Yamada K, Gibo N, Aoki T, Kataoka K, Mori H, Takada Y, Takahashi H, Aoi H, Kato K, Yamamura T, Kakushima N, Furukawa K, Nakamura M, Hirooka Y, Kawashima H

    Canadian journal of gastroenterology & hepatology   Vol. 2022   page: 2737578   2022

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    DOI: 10.1155/2022/2737578

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  27. Comparison of contrast-enhanced transabdominal ultrasonography following endoscopic ultrasonography with GD-EOB-DTPA-enhanced MRI for the sequential diagnosis of liver metastasis in patients with pancreatic cancer

    Ishikawa Takuya, Ohno Eizaburo, Mizutani Yasuyuki, Iida Tadashi, Koya Toshinari, Sasaki Yutaka, Ogawa Hiroshi, Kinoshita Fumie, Hirooka Yoshiki, Kawashima Hiroki

    JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES     2021.12

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  28. Real-world local recurrence rate after cold polypectomy in colorectal polyps less than 10 mm using propensity score matching

    Saito Masashi, Yamamura Takeshi, Nakamura Masanao, Maeda Keiko, Sawada Tsunaki, Ishikawa Eri, Mizutani Yasuyuki, Ishikawa Takuya, Kakushima Naomi, Furukawa Kazuhiro, Ohno Eizaburo, Kawashima Hiroki, Ishigami Masatoshi, Fujishiro Mitsuhiro

    WORLD JOURNAL OF GASTROENTEROLOGY   Vol. 27 ( 47 ) page: 8182 - 8193   2021.12

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  29. Changes in the gut microbiota after hepatitis C virus eradication

    Honda Takashi, Ishigami Masatoshi, Yamamoto Kenta, Takeyama Tomoaki, Ito Takanori, Ishizu Yoji, Kuzuya Teiji, Nakamura Masanao, Kawashima Hiroki, Miyahara Ryoji, Ishikawa Tetsuya, Hirooka Yoshiki, Fujishiro Mitsuhiro

    SCIENTIFIC REPORTS   Vol. 11 ( 1 ) page: 23568   2021.12

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  30. Obesity and myosteatosis: the two characteristics of dynapenia in patients with cirrhosis

    Sugiyama Yoshiaki, Ishizu Yoji, Ando Yusuke, Yokoyama Shinya, Yamamoto Kenta, Ito Takanori, Imai Norihiro, Nakamura Masanao, Honda Takashi, Kawashima Hiroki, Ishikawa Tetsuya, Ishigami Masatoshi

    EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY   Vol. 33 ( 1S Suppl 1 ) page: E916 - E921   2021.12

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  31. Clinical characteristics of gastrointestinal immune-related adverse events of immune checkpoint inhibitors and their association with survival

    Yamada Kentaro, Sawada Tsunaki, Nakamura Masanao, Yamamura Takeshi, Maeda Keiko, Ishikawa Eri, Iida Tadashi, Mizutani Yasuyuki, Kakushima Naomi, Ishikawa Takuya, Furukawa Kazuhiro, Ohno Eizaburo, Honda Takashi, Kawashima Hiroki, Ishigami Masatoshi, Furune Satoshi, Hase Tetsunari, Yokota Kenji, Maeda Osamu, Hashimoto Naozumi, Akiyama Masashi, Ando Yuichi, Fujishiro Mitsuhiro

    WORLD JOURNAL OF GASTROENTEROLOGY   Vol. 27 ( 41 ) page: 7190 - 7206   2021.11

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  32. An Unusual Pancreatic Mass with Ductal Disruption: Benign or Malignant? Reviewed International journal

    Takada Y, Ishikawa T, Kawashima H

    Gastroenterology   Vol. 161 ( 4 ) page: 1113 - 1115   2021.10

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    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1053/j.gastro.2021.06.059

    PubMed

  33. Imaging diagnosis of autoimmune pancreatitis using endoscopic ultrasonography

    Ishikawa Takuya, Kawashima Hiroki, Ohno Eizaburo, Mizutani Yasuyuki, Fujishiro Mitsuhiro

    JOURNAL OF MEDICAL ULTRASONICS   Vol. 48 ( 4 ) page: 543 - 553   2021.10

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  34. Endoscopic resection of a duodenal neuroendocrine tumor. Reviewed International journal

    Furukawa K, Nakamura M, Kawashima H, Fujishiro M

    Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva     2021.9

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    DOI: 10.17235/reed.2021.8232/2021

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  35. Endoscopic Ultrasound Elastography as a Novel Diagnostic Method for the Assessment of Hardness and Depth of Invasion in Colorectal Neoplasms Reviewed International journal

    Esaki Masaya, Yamamura Takeshi, Nakamura Masanao, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Eri, Suzuki Hiroto, Kuno Takeshi, Yamada Kentaro, Hasegawa Issei, Ishikawa Takuya, Kakushima Naomi, Furukawa Kazuhiro, Ohno Eizaburo, Kawashima Hiroki, Hirooka Yoshiki, Fujishiro Mitsuhiro

    DIGESTION   Vol. 102 ( 5 ) page: 701 - 713   2021.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1159/000511589

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  36. Late postoperative complications of congenital biliary dilatation in pediatric patients: a single-center experience of managing complications for over 20 years

    Amano Hizuru, Shirota Chiyoe, Tainaka Takahisa, Sumida Wataru, Yokota Kazuki, Makita Satoshi, Takimoto Aitaro, Tanaka Yujiro, Hinoki Akinari, Kawashima Hiroki, Uchida Hiroo

    SURGERY TODAY   Vol. 51 ( 9 ) page: 1488 - 1495   2021.9

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  37. Gastrointestinal: Idiopathic omental hemorrhage Reviewed

    Furukawa K., Yamamura T., Nakamura M., Kawashima H., Fujishiro M.

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY     2021.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/jgh.15639

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  38. Clinical course of liver injury induced by immune checkpoint inhibitors in patients with advanced malignancies Reviewed International journal

    Ito Takanori, Ishigami Masatoshi, Yamamoto Takafumi, Mizuno Kazuyuki, Yamamoto Kenta, Imai Norihiro, Ishizu Yoji, Honda Takashi, Kawashima Hiroki, Yasuda Satoshi, Toyoda Hidenori, Yokota Kenji, Hase Tetsunari, Nishio Naoki, Maeda Osamu, Kato Masashi, Hashimoto Naozumi, Hibi Hideharu, Kodera Yasuhiro, Sone Michihiko, Ando Yuichi, Akiyama Masashi, Shimoyama Yoshie, Fujishiro Mitsuhiro

    HEPATOLOGY INTERNATIONAL   Vol. 15 ( 5 ) page: 1278 - 1287   2021.8

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    DOI: 10.1007/s12072-021-10238-y

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  39. A novel scoring system to predict therapeutic intervention for non-variceal upper gastrointestinal bleeding Reviewed International journal

    Ito Nobuhito, Funasaka Kohei, Furukawa Kazuhiro, Kakushima Naomi, Hirose Takashi, Muroi Koichi, Suzuki Tomohiko, Suzuki Takahiro, Hida Emiko, Ishikawa Takuya, Yamamura Takeshi, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Miyahara Ryoji, Fujishiro Mitsuhiro

    INTERNAL AND EMERGENCY MEDICINE     2021.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s11739-021-02822-9

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  40. A forward-viewing radial-array echoendoscope is useful for diagnosing the depth of colorectal neoplasia invasion Reviewed International journal

    Kuno Takeshi, Yamamura Takeshi, Nakamura Masanao, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Esaki Masaya, Ishikawa Takuya, Furukawa Kazuhiro, Ohno Eizaburo, Kawashima Hiroki, Fujishiro Mitsuhiro

    SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES   Vol. 35 ( 8 ) page: 4389 - 4398   2021.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00464-020-07936-3

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  41. Detection of Colorectal Neoplasms Using Linked Color Imaging: A Prospective, Randomized, Tandem Colonoscon Trial Reviewed International journal

    Hasegawa Issei, Yamamura Takeshi, Suzuki Hiroto, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Eri, Ishikawa Takuya, Kakushima Naomi, Furukawa Kazuhiro, Ohno Eizaburo, Kawashima Hiroki, Nakamura Masanao, Fujishiro Mitsuhiro

    CLINICAL GASTROENTEROLOGY AND HEPATOLOGY   Vol. 19 ( 8 ) page: 1708 - +   2021.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.cgh.2021.04.004

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  42. Feasibility of patency capsule and colon capsule endoscopy in patients with suspected gastrointestinal stenosis: a prospective study. Reviewed International journal

    Otsuka H, Nakamura M, Yamamura T, Maeda K, Sawada T, Mizutani Y, Ishikawa E, Ishikawa T, Kakushima N, Furukawa K, Ohno E, Kawashima H, Honda T, Ishigami M, Fujishiro M

    Nagoya journal of medical science   Vol. 83 ( 3 ) page: 419 - 430   2021.8

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    DOI: 10.18999/nagjms.83.3.419

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  43. Double common bile duct associated with pancreaticobiliary maljunction Reviewed International journal

    Yamada Kenta, Ishikawa Takuya, Ohno Eizaburo, Iida Tadashi, Suzuki Hirotaka, Uetsuki Kota, Yashika Jun, Yoshikawa Masakatsu, Takami Hideki, Inokawa Yoshikuni, Uchida Hiroo, Kawashima Hiroki, Fujishiro Mitsuhiro

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 83 ( 3 ) page: 655 - 661   2021.8

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.18999/nagjms.83.3.655

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  44. Fecal incontinence and oral regurgitation during duodenal endoscopic submucosal dissection using the water pressure method Reviewed International journal

    Takada Yoshihisa, Hirose Takashi, Nishida Kazuki, Kakushima Naomi, Furukawa Kazuhiro, Furune Satoshi, Ishikawa Eri, Sawada Tsunaki, Maeda Keiko, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Honda Takashi, Ishigami Masatoshi, Kawashima Hiroki, Fujishiro Mitsuhiro

    DIGESTIVE ENDOSCOPY     2021.7

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/den.14070

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  45. Differentiation between pancreatic metastases from renal cell carcinoma and pancreatic neuroendocrine neoplasm using endoscopic ultrasound. Reviewed International journal

    Kataoka K, Ishikawa T, Ohno E, Mizutani Y, Iida T, Ishikawa E, Furukawa K, Nakamura M, Honda T, Ishigami M, Kawashima H, Hirooka Y, Fujishiro M

    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]     2021.7

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    DOI: 10.1016/j.pan.2021.07.001

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  46. Evaluation of ulcerative colitis activity using transabdominal ultrasound shear wave elastography Reviewed International journal

    Yamada Kenta, Ishikawa Takuya, Kawashima Hiroki, Ohno Eizaburo, Iida Tadashi, Ishikawa Eri, Mizutani Yasuyuki, Sawada Tsunaki, Maeda Keiko, Yamamura Takeshi, Kakushima Naomi, Furukawa Kazuhiro, Nakamura Masanao, Ishigami Masatoshi, Fujishiro Mitsuhiro

    QUANTITATIVE IMAGING IN MEDICINE AND SURGERY     2021.7

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    DOI: 10.21037/qims-21-403

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  47. Lewis score on capsule endoscopy can predict the prognosis in patients with small bowel lesions of Crohn's disease Reviewed International journal

    Nishikawa Takahiro, Nakamura Masanao, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Eri, Ishikawa Takuya, Kakushima Naomi, Furukawa Kazuhiro, Ohno Eizaburo, Honda Takashi, Kawashima Hiroki, Ishigami Masatoshi, Fujishiro Mitsuhiro

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 36 ( 7 ) page: 1851 - 1858   2021.7

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    DOI: 10.1111/jgh.15366

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  48. Subjective Symptoms in Patients with Eosinophilic Esophagitis Are Related to Esophageal Wall Thickness and Esophageal Body Pressure Reviewed

    Muroi Koichi, Kakushima Naomi, Furukawa Kazuhiro, Ishikawa Eri, Sawada Tsunaki, Ishikawa Takuya, Maeda Keiko, Yamamura Takeshi, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Funasaka Kohei, Miyahara Ryoji, Fujishiro Mitsuhiro

    DIGESTIVE DISEASES AND SCIENCES   Vol. 66 ( 7 ) page: 2291 - 2300   2021.7

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  49. Indications and Limitations Associated with the Patency Capsule Prior to Capsule Endoscopy. Reviewed International journal

    Nakamura M, Kawashima H, Ishigami M, Fujishiro M

    Internal medicine (Tokyo, Japan)     2021.6

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    DOI: 10.2169/internalmedicine.6823-20

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  50. Endocytoscopy Is Useful for the Diagnosis of Superficial Nonampullary Duodenal Epithelial Tumors Reviewed International journal

    Hirose Takashi, Kakushima Naomi, Furukawa Kazuhiro, Furune Satoshi, Ishikawa Eri, Sawada Tsunaki, Maeda Keiko, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Nishida Kazuki, Yokoi Takio, Kawashima Hiroki, Fujishiro Mitsuhiro

    DIGESTION     page: 1 - 8   2021.6

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    DOI: 10.1159/000516512

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  51. An evaluation of resectability among endoscopic treatment methods for rectal neuroendocrine tumors < 10 mm Reviewed International journal

    Toriyama Kazuhiro, Yamamura Takeshi, Nakamura Masanao, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Eri, Furukawa Kazuhiro, Ishikawa Takuya, Ohno Eizaburo, Kawashima Hiroki, Fujishiro Mitsuhiro

    ARAB JOURNAL OF GASTROENTEROLOGY   Vol. 22 ( 2 ) page: 104 - 110   2021.6

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    DOI: 10.1016/j.ajg.2021.05.007

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  52. Comparison of High-Resolution Manometry in Patients Complaining of Dysphagia among Patients with or without Diabetes Mellitus Reviewed International journal

    Muroi Koichi, Miyahara Ryoji, Funasaka Kohei, Furukawa Kazuhiro, Sawada Tsunaki, Maeda Keiko, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Onoue Takeshi, Arima Hiroshi, Hirooka Yoshiki, Fujishiro Mitsuhiro

    DIGESTION   Vol. 102 ( 4 ) page: 554 - 562   2021.6

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    DOI: 10.1159/000510081

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  53. An initial trial of quantitative evaluation of autoimmune pancreatitis using shear wave elastography and shear wave dispersion in transabdominal ultrasound. Reviewed International journal

    Suzuki H, Ishikawa T, Ohno E, Iida T, Uetsuki K, Yashika J, Yamada K, Yoshikawa M, Furukawa K, Nakamura M, Honda T, Ishigami M, Kawashima H, Fujishiro M

    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]   Vol. 21 ( 4 ) page: 682 - 687   2021.6

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    DOI: 10.1016/j.pan.2021.02.014

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  54. Long-Term Prognostic Predictors of Esophageal Squamous Cell Carcinoma Potentially Indicated for Endoscopic Submucosal Dissection Reviewed International journal

    Suzuki Tomohiko, Furukawa Kazuhiro, Funasaka Kohei, Ishikawa Eri, Sawada Tsunaki, Maeda Keiko, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Miyahara Ryoji, Fujishiro Mitsuhiro

    DIGESTION   Vol. 102 ( 4 ) page: 563 - 571   2021.6

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    DOI: 10.1159/000510091

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  55. Double-balloon endoscopic retrograde cholangiography can make a reliable diagnosis and good prognosis for postoperative complications of congenital biliary dilatation Reviewed International journal

    Shirota Chiyoe, Kawashima Hiroki, Tainaka Takahisa, Sumida Wataru, Yokota Kazuki, Makita Satoshi, Amano Hizuru, Takimoto Aitaro, Hinoki Akinari, Uchida Hiroo

    SCIENTIFIC REPORTS   Vol. 11 ( 1 ) page: 11052   2021.5

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    DOI: 10.1038/s41598-021-90550-7

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  56. Immunohistochemical staining for IMP3 in patients with duodenal papilla tumors: assessment of the potential for diagnosing endoscopic resectability and predicting prognosis Reviewed International journal

    Tanaka Hiroyuki, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Iida Tadashi, Ishikawa Eri, Furukawa Kazuhiro, Nakamura Masanao, Honda Takashi, Shimoyama Yoshie, Miyahara Ryoji, Kawabe Naoto, Kuzuya Teiji, Hashimoto Senju, Ishigami Masatoshi, Hirooka Yoshiki, Fujishiro Mitsuhiro

    BMC GASTROENTEROLOGY   Vol. 21 ( 1 ) page: 224   2021.5

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    DOI: 10.1186/s12876-021-01811-8

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  57. Measurement of fasting breath hydrogen concentration as a simple diagnostic method for pancreatic exocrine insufficiency

    Uetsuki Kota, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Iida Tadashi, Yamamoto Kenta, Furukawa Kazuhiro, Nakamura Masanao, Honda Takashi, Ishigami Masatoshi, Hirooka Yoshiki, Fujishiro Mitsuhiro

    BMC GASTROENTEROLOGY   Vol. 21 ( 1 ) page: 211   2021.5

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  58. Diagnostic performance of endoscopic ultrasonography-guided elastography for solid pancreatic lesions: Shear-wave measurements versus strain elastography with histogram analysis Reviewed International journal

    Ohno Eizaburo, Kawashima Hiroki, Ishikawa Takuya, Iida Tadashi, Suzuki Hirotaka, Uetsuki Kota, Yashika Jun, Yamada Kenta, Yoshikawa Masakatsu, Gibo Noriaki, Aoki Toshinori, Kataoka Kunio, Mori Hiroshi, Yamamura Takeshi, Furukawa Kazuhiro, Nakamura Masanao, Hirooka Yoshiki, Fujishiro Mitsuhiro

    DIGESTIVE ENDOSCOPY   Vol. 33 ( 4 ) page: 629 - 638   2021.5

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    DOI: 10.1111/den.13791

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  59. New modality for the quantitative evaluation of tissue elasticity using a forward-viewing radial-array echoendoscope for colorectal neoplasms Reviewed

    Esaki Masaya, Yamamura Takeshi, Nakamura Masanao, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Eri, Furukawa Kazuhiro, Kawashima Hiroki, Hirooka Yoshiki, Fujishiro Mitsuhiro

    INTERNATIONAL JOURNAL OF COLORECTAL DISEASE   Vol. 36 ( 5 ) page: 919 - 927   2021.5

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  60. Endoscopic removal of a fish bone piercing the bile duct after pancreaticoduodenectomy Reviewed International journal

    Ishikawa Takuya, Kawashima Hiroki, Ohno Eizaburo, Nakamura Masanao, Yamada Suguru, Hayashi Masamichi, Fujishiro Mitsuhiro

    ENDOSCOPY   Vol. 53 ( 05 ) page: E164 - E165   2021.5

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    DOI: 10.1055/a-1224-3724

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  61. Variability measurements provide additional value to shear wave elastography in the diagnosis of pancreatic cancer

    Yoshikawa Masakatsu, Ishikawa Takuya, Ohno Eizaburo, Iida Tadashi, Furukawa Kazuhiro, Nakamura Masanao, Honda Takashi, Ishigami Masatoshi, Kinoshita Fumie, Kawashima Hiroki, Fujishiro Mitsuhiro

    SCIENTIFIC REPORTS   Vol. 11 ( 1 ) page: 7409   2021.4

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  62. Filtrated Adipose Tissue-Derived Mesenchymal Stem Cell Lysate Ameliorates Experimental Acute Colitis in Mice Reviewed International journal

    Nishikawa Takahiro, Maeda Keiko, Nakamura Masanao, Yamamura Takeshi, Sawada Tsunaki, Mizutani Yasuyuki, Ito Takanori, Ishikawa Takuya, Furukawa Kazuhiro, Ohno Eizaburo, Miyahara Ryoji, Kawashima Hiroki, Honda Takashi, Ishigami Masatoshi, Yamamoto Tokunori, Matsumoto Seiji, Hotta Yuji, Fujishiro Mitsuhiro

    DIGESTIVE DISEASES AND SCIENCES   Vol. 66 ( 4 ) page: 1034 - 1044   2021.4

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    DOI: 10.1007/s10620-020-06359-3

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  63. Gastrointestinal: Pancreatic metastasis from extramammary Paget's disease diagnosed by endoscopic ultrasound-guided fine-needle biopsy Reviewed International journal

    Suzuki H., Ishikawa T., Ohno E., Kawashima H., Fujishiro M.

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY     2021.3

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    DOI: 10.1111/jgh.15444

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  64. Microbiome, fibrosis and tumor networks in a non-alcoholic steatohepatitis model of a choline-deficient high-fat diet using diethylnitrosamine.

    Yamamoto K, Honda T, Yokoyama S, Ma L, Kato A, Ito T, Ishizu Y, Kuzuya T, Nakamura M, Kawashima H, Ishigami M, Tsuji NM, Fujishiro M

    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver     2021.3

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    DOI: 10.1016/j.dld.2021.02.013

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  65. The relationship between oral-origin bacteria in the fecal microbiome and albumin-bilirubin grade in patients with hepatitis C Reviewed

    Yamamoto Kenta, Honda Takashi, Ito Takanori, Ishizu Yoji, Kuzuya Teiji, Nakamura Masanao, Miyahara Ryoji, Kawashima Hiroki, Ishigami Masatoshi, Fujishiro Mitsuhiro

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 36 ( 3 ) page: 790 - 799   2021.3

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  66. Endoscopic ultrasound elastography for small solid pancreatic lesions with or without main pancreatic duct dilatation Reviewed International journal

    Kataoka Kunio, Ishikawa Takuya, Ohno Eizaburo, Iida Tadashi, Suzuki Hirotaka, Uetsuki Kota, Furukawa Kazuhiro, Nakamura Masanao, Honda Takashi, Ishigami Masatoshi, Kawashima Hiroki, Hirooka Yoshiki, Fujishiro Mitsuhiro

    PANCREATOLOGY   Vol. 21 ( 2 ) page: 451 - 458   2021.3

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    DOI: 10.1016/j.pan.2020.12.012

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  67. Utility of multiphase contrast enhancement patterns on CEH-EUS for the differential diagnosis of IPMN-derived and conventional pancreatic cancer

    Yashika Jun, Ohno Eizaburo, Ishikawa Takuya, Iida Tadashi, Suzuki Hirotaka, Uetsuki Kota, Yamada Kenta, Yoshikawa Masakatsu, Gibo Noriaki, Shimoyama Yoshie, Ishikawa Eri, Furukawa Kazuhiro, Nakamura Masanao, Honda Takashi, Ishigami Masatoshi, Hirooka Yoshiki, Kawashima Hiroki, Fujishiro Mitsuhiro

    PANCREATOLOGY   Vol. 21 ( 2 ) page: 390 - 396   2021.3

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  68. Diagnostic yield of colon capsule endoscopy for Crohn's disease lesions in the whole gastrointestinal tract Reviewed International journal

    Yamada Keisaku, Nakamura Masanao, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Eri, Ishikawa Takuya, Kakushima Naomi, Furukawa Kazuhiro, Ohno Eizaburo, Kawashima Hiroki, Honda Takashi, Ishigami Masatoshi, Fujishiro Mitsuhiro

    BMC GASTROENTEROLOGY   Vol. 21 ( 1 ) page: 75   2021.2

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    DOI: 10.1186/s12876-021-01657-0

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  69. Ustekinumab is effective against small bowel lesions in Crohn's disease: two case reports

    Murate Kentaro, Nakamura Masanao, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Eri, Kakushima Naomi, Furukawa Kazuhiro, Ohno Eizaburo, Honda Takashi, Kawashima Hiroki, Ishigami Masatoshi, Fujishiro Mitsuhiro

    CLINICAL JOURNAL OF GASTROENTEROLOGY   Vol. 14 ( 1 ) page: 129 - 135   2021.2

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  70. Clinical characteristics and long-term prognosis of autoimmune pancreatitis with renal lesions Reviewed International journal

    Ishikawa Takuya, Kawashima Hiroki, Ohno Eizaburo, Iida Tadashi, Suzuki Hirotaka, Uetsuki Kota, Yashika Jun, Yamada Kenta, Yoshikawa Masakatsu, Gibo Noriaki, Aoki Toshinori, Kataoka Kunio, Mori Hiroshi, Yamamura Takeshi, Furukawa Kazuhiro, Nakamura Masanao, Hirooka Yoshiki, Fujishiro Mitsuhiro

    SCIENTIFIC REPORTS   Vol. 11 ( 1 ) page: 406   2021.1

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    DOI: 10.1038/s41598-020-79899-3

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  71. Gastrointestinal tract metastasis of lung cancer: The PD-L1 expression and correlated clinicopathological variables Reviewed International journal

    Ishikawa Eri, Nakaguro Masato, Nakamura Masanao, Yamamura Takeshi, Sawada Tsunaki, Mizutani Yasuyuki, Maeda Keiko, Furukawa Kazuhiro, Shimoyama Yoshie, Kawashima Hiroki, Fujishiro Mitsuhiro

    PATHOLOGY INTERNATIONAL   Vol. 71 ( 1 ) page: 33 - 41   2021.1

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    DOI: 10.1111/pin.13048

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  72. Systematic review and meta-analysis of the diagnostic and therapeutic yield of small bowel endoscopy in patients with overt small bowel bleeding Reviewed

    Uchida Genta, Nakamura Masanao, Yamamura Takeshi, Furukawa Kazuhiro, Kawashima Hiroki, Honda Takashi, Ishigami Masatoshi, Fujishiro Mitsuhiro

    DIGESTIVE ENDOSCOPY   Vol. 33 ( 1 ) page: 66 - 82   2021.1

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  73. Clinical Features of Ischemic Enteritis Diagnosed by Double-Balloon Endoscopy. Reviewed International journal

    Nakamura M, Yamamura T, Maeda K, Sawada T, Mizutani Y, Ishikawa E, Kakushima N, Furukawa K, Ishikawa T, Ohno E, Honda T, Kawashima H, Ishigami M, Fujishiro M

    Canadian journal of gastroenterology & hepatology   Vol. 2021   page: 8875564   2021

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    DOI: 10.1155/2021/8875564

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  74. Surgical mask designed for endoscopic procedures to prevent the diffusion of droplets

    Furukawa K., Sato K., Okachi S., Kawashima H., Fujishiro M.

    ACTA GASTRO-ENTEROLOGICA BELGICA   Vol. 84 ( 3 ) page: 517 - 519   2021

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    DOI: 10.51821/84.3.024

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  75. Collision Tumors of Gastric Adenocarcinoma and Mucosa-associated Lymphoid Tissue Lymphoma Reviewed International journal

    Kobayashi Kenichi, Furukawa Kazuhiro, Ishikawa Eri, Mitsuma Ayako, Funasaka Kohei, Kakushima Naomi, Furune Satoshi, Ito Nobuhito, Wada Hirotaka, Hirose Takashi, Muroi Koichi, Suzuki Tomohiko, Suzuki Takahiro, Hida Emiko, Hirai Keiko, Shibata Hiroyuki, Koya Toshinari, Nakamura Masanao, Kawashima Hiroki, Miyahara Ryoji, Fujishiro Mitsuhiro

    INTERNAL MEDICINE   Vol. 60 ( 15 ) page: 2419 - 2424   2021

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    DOI: 10.2169/internalmedicine.6124-20

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  76. Risks and characteristics of pancreatic cancer and pancreatic relapse in autoimmune pancreatitis patients Reviewed

    Ishikawa Takuya, Kawashima Hiroki, Ohno Eizaburo, Iida Tadashi, Suzuki Hirotaka, Uetsuki Kota, Yamada Kenta, Yashika Jun, Yoshikawa Masakatsu, Gibo Noriaki, Aoki Toshinori, Kataoka Kunio, Mori Hiroshi, Fujishiro Mitsuhiro

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 35 ( 12 ) page: 2281 - 2288   2020.12

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  77. The microbiome can predict mucosal healing in small intestine in patients with Crohn's disease Reviewed

    Hattori Shun, Nakamura Masanao, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Yamamoto Kenta, Ishikawa Takuya, Furukawa Kazuhiro, Ohno Eizaburo, Honda Takashi, Kawashima Hiroki, Ishigami Masatoshi, Hirooka Yoshiki, Fujishiro Mitsuhiro

    JOURNAL OF GASTROENTEROLOGY   Vol. 55 ( 12 ) page: 1138 - 1149   2020.12

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  78. Glycoproteomic analysis identifies cryptdin-related sequence 1 as O-glycosylated protein modified with alpha 1,2-fucose in the small intestine Reviewed International journal

    Hashiguchi Hiroki, Tsukamoto Yohei, Ogawa Mitsutaka, Tashima Yuko, Takeuchi Hideyuki, Nakamura Masanao, Kawashima Hiroki, Fujishiro Mitsuhiro, Okajima Tetsuya

    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS   Vol. 695   page: 108653   2020.11

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    DOI: 10.1016/j.abb.2020.108653

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  79. Accuracy of carbon dioxide insufflation for endoscopic retrograde cholangiopancreatography using double-balloon endoscopy Reviewed International journal

    Niwa Yoshiki, Nakamura Masanao, Kawashima Hiroki, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Eri, Ishikawa Takuya, Kakushima Naomi, Furukawa Kazuhiro, Ohno Eizaburo, Honda Takashi, Ishigami Masatoshi, Fujishiro Mitsuhiro

    WORLD JOURNAL OF GASTROENTEROLOGY   Vol. 26 ( 42 ) page: 6669 - 6678   2020.11

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    DOI: 10.3748/wjg.v26.i42.6669

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  80. Endoscopic Activity and Serum TNF-alpha Level at Baseline Are Associated With Clinical Response to Ustekinumab in Crohn's Disease Patients Reviewed International journal

    Murate Kentaro, Maeda Keiko, Nakamura Masanao, Sugiyama Daisuke, Wada Hirotaka, Yamamura Takeshi, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Takuya, Furukawa Kazuhiro, Ohno Eizaburo, Honda Takashi, Kawashima Hiroki, Miyahara Ryoji, Ishigami Masatoshi, Nishikawa Hiroyoshi, Fujishiro Mitsuhiro

    INFLAMMATORY BOWEL DISEASES   Vol. 26 ( 11 ) page: 1669 - 1681   2020.11

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    DOI: 10.1093/ibd/izaa086

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  81. Mutation analysis of gastrointestinal stromal tumors using RNA obtained via endoscopic ultrasound-guided fine-needle aspiration Reviewed

    Funasaka Kohei, Miyahara Ryoji, Furukawa Kazuhiro, Sawada Tsunaki, Maeda Keiko, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Hirooka Yoshiki, Ohmiya Naoki, Fujishiro Mitsuhiro

    TRANSLATIONAL ONCOLOGY   Vol. 13 ( 11 ) page: 100848   2020.11

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  82. Usefulness of endoscopic ultrasound-guided fine-needle biopsy for the diagnosis of autoimmune pancreatitis using a 22-gauge Franseen needle: a prospective multicenter study

    Ishikawa Takuya, Kawashima Hiroki, Ohno Eizaburo, Suhara Hiroki, Hayashi Daijuro, Hiramatsu Takeshi, Matsubara Hiroshi, Suzuki Takahisa, Kuwahara Takamichi, Ishikawa Eri, Shimoyama Yoshie, Kinoshita Fumie, Hirooka Yoshiki, Fujishiro Mitsuhiro

    ENDOSCOPY   Vol. 52 ( 11 ) page: 978 - 985   2020.11

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  83. What is the role of measuring shear wave dispersion using shear wave elastography in pancreatic parenchyma? Reviewed

    Suzuki Hirotaka, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Hashimoto Senju, Nakamura Masanao, Miyahara Ryoji, Ishigami Masatoshi, Hirooka Yoshiki, Fujishiro Mitsuhiro

    JOURNAL OF MEDICAL ULTRASONICS   Vol. 47 ( 4 ) page: 575 - 581   2020.10

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  84. Low ETV1 mRNA expression is associated with recurrence in gastrointestinal stromal tumors

    Sakamaki Keiichi, Funasaka Kohei, Miyahara Ryoji, Furukawa Kazuhiro, Yamamura Takeshi, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Hirooka Yoshiki, Fujishiro Mitsuhiro, Goto Hidemi

    SCIENTIFIC REPORTS   Vol. 10 ( 1 ) page: 14767   2020.9

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  85. Can contrast-enhanced harmonic endoscopic ultrasonography accurately diagnose main pancreatic duct involvement in intraductal papillary mucinous neoplasms? Reviewed International journal

    Ohno Eizaburo, Kawashima Hiroki, Ishikawa Takuya, Iida Tadashi, Suzuki Hirotaka, Uetsuki Kota, Yashika Jun, Yamada Kenta, Yoshikawa Masakatsu, Gibo Noriaki, Aoki Toshinori, Kataoka Kunio, Mori Hiroshi, Hirooka Yoshiki, Fujishiro Mitsuhiro

    PANCREATOLOGY   Vol. 20 ( 5 ) page: 887 - 894   2020.7

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    DOI: 10.1016/j.pan.2020.06.004

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  86. Gender difference in the transabdominal ultrasound findings of solid-pseudopapillary neoplasm Reviewed International journal

    Sasaki Yutaka, Ishikawa Takuya, Kawashima Hiroki, Ohno Eizaburo, Shimoyama Yoshie, Ishikawa Eri, Fujishiro Mitsuhiro

    PANCREATOLOGY   Vol. 20 ( 5 ) page: 997 - 1003   2020.7

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    DOI: 10.1016/j.pan.2020.06.016

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  87. Endoscopic ultrasonography for the evaluation of pancreatic cystic neoplasms Reviewed International journal

    Ohno Eizaburo, Hirooka Yoshiki, Kawashima Hiroki, Ishikawa Takuya, Fujishiro Mitsuhiro

    JOURNAL OF MEDICAL ULTRASONICS   Vol. 47 ( 3 ) page: 401 - 411   2020.7

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    DOI: 10.1007/s10396-019-00980-0

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  88. Use of Immunostaining for the diagnosis of Lymphovascular invasion in superficial Barrett's esophageal adenocarcinoma

    Hosono Isao, Miyahara Ryoji, Furukawa Kazuhiro, Funasaka Kohei, Sawada Tsunaki, Maeda Keiko, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Yokoi Takio, Hirooka Yoshiki, Fujishiro Mitsuhiro, Tsukamoto Tetsuya

    BMC GASTROENTEROLOGY   Vol. 20 ( 1 ) page: 175   2020.6

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  89. EVALUATION OF RESECTABILITY BETWEEN ENDOSCOPIC TREATMENT METHODS FOR RECTAL NEUROENDOCRINE TUMOR Reviewed International journal

    Toriyama Kazuhiro, Yamamura Takeshi, Nakamura Masanao, Keiko Maeda, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Takuya, Furukawa Kazuhiro, Ohno Eizaburo, Kawashima Hiroki, Fujishiro Mitsuhiro

    GASTROINTESTINAL ENDOSCOPY   Vol. 91 ( 6 ) page: AB101 - AB101   2020.6

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  90. Real world data of liver injury induced by immune checkpoint inhibitors in Japanese patients with advanced malignancies Reviewed

    Mizuno Kazuyuki, Ito Takanori, Ishigami Masatoshi, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Kawashima Hiroki, Inukai Yosuke, Toyoda Hidenori, Yokota Kenji, Hase Tetsunari, Maeda Osamu, Kiyoi Hitoshi, Nagino Masato, Hibi Hideharu, Kodera Yasuhiro, Fujimoto Yasushi, Sone Michihiko, Gotoh Momokazu, Ando Yuichi, Akiyama Masashi, Hasegawa Yoshinori, Fujishiro Mitsuhiro

    JOURNAL OF GASTROENTEROLOGY   Vol. 55 ( 6 ) page: 653 - 661   2020.6

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  91. PROSPECTIVE MULTICENTER STUDY ON THE USEFULNESS OF EUS-GUIDED FINE NEEDLE BIOPSY FOR THE DIAGNOSIS OF AUTOIMMUNE PANCREATITIS USING A 22-GAUGE FRANSEEN NEEDLE

    Ishikawa Takuya, Kawashima Hiroki, Ohno Eizaburo, Nishio Ryo, Iida Tadashi, Suzuki Hirotaka, Uetsuki Kota, Yamada Kenta, Yashika Jun, Yoshikawa Masakatsu, Gibo Noriaki, Aoki Toshinori, Kataoka Kunio, Mori Hiroshi, Keiko Maeda, Sawada Tsunaki, Yamamura Takeshi, Furukawa Kazuhiro, Nakamura Masanao, Fujishiro Mitsuhiro

    GASTROINTESTINAL ENDOSCOPY   Vol. 91 ( 6 ) page: AB172 - AB172   2020.6

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  92. NOVEL METHOD TO DETERMINE THE DEPTH OF INVASION IN COLORECTAL NEOPLASMS WITH ULTRASOUND ELASTOGRAPHY USING A FORWARD-VIEWING RADIAL-ARRAY ECHOENDOSCOPE

    Esaki Masaya, Yamamura Takeshi, Nakamura Masanao, Keiko Maeda, Sawada Tsunaki, Mizutani Yasuyuki, Kuno Takeshi, Yamada Kentaro, Hasegawa Issei, Ishikawa Takuya, Furukawa Kazuhiro, Ohno Eizaburo, Kawashima Hiroki, Fujishiro Mitsuhiro

    GASTROINTESTINAL ENDOSCOPY   Vol. 91 ( 6 ) page: AB430 - AB430   2020.6

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  93. ENDOSCOPIC DIAGNOSIS USING MAGNIFYING IMAGE-ENHANCED ENDOSCOPY FOR SUPERFICIAL NON-AMPULLARY DUODENAL EPITHELIAL TUMORS Reviewed International journal

    Furukawa Kazuhiro, Miyahara Ryoji, Funasaka Kohei, Sawada Tsunaki, Keiko Maeda, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Fujishiro Mitsuhiro

    GASTROINTESTINAL ENDOSCOPY   Vol. 91 ( 6 ) page: AB618 - AB618   2020.6

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  94. Clinical Factors Associated with Missing Colorectal Polyp on Colon Capsule Endoscopy Reviewed International journal

    Yamada Keisaku, Nakamura Masanao, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Takuya, Furukawa Kazuhiro, Ohno Eizaburo, Miyahara Ryoji, Kawashima Hiroki, Hotta Naoki, Hirooka Yoshiki

    DIGESTION   Vol. 101 ( 3 ) page: 316 - 322   2020.5

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    DOI: 10.1159/000498942

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  95. Nonexposed wall-inversion surgery as a novel local resection method for neoplasms in the gastrointestinal tract Invited Reviewed

    Fujishiro Mitsuhiro, Furukawa Kazuhiro, Yamamura Takeshi, Nakamura Masanao, Honda Takashi, Maeda Osamu, Ishigami Masatoshi, Kawashima Hiroki

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 82 ( 2 ) page: 175 - 182   2020.5

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  96. Diagnosis of vascular invasion in pancreatic ductal adenocarcinoma using endoscopic ultrasound elastography Reviewed International journal

    Yamada Kenta, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Tanaka Hiroyuki, Nakamura Masanao, Miyahara Ryoji, Ishigami Masatoshi, Hirooka Yoshiki, Fujishiro Mitsuhiro

    BMC GASTROENTEROLOGY   Vol. 20 ( 1 ) page: 81   2020.3

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    DOI: 10.1186/s12876-020-01228-9

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  97. Double-balloon endoscopic retrograde cholangiopancreatography for patients who underwent liver operation: A retrospective study Reviewed International journal

    Nishio Ryo, Kawashima Hiroki, Nakamura Masanao, Ohno Eizaburo, Ishikawa Takuya, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Tanaka Hiroyuki, Sakai Daisuke, Miyahara Ryoji, Ishigami Masatoshi, Hirooka Yoshiki, Fujishiro Mitsuhiro

    WORLD JOURNAL OF GASTROENTEROLOGY   Vol. 26 ( 10 ) page: 1056 - 1066   2020.3

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    DOI: 10.3748/wjg.v26.i10.1056

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  98. Relationship Between Adverse Events and Microbiomes in Advanced Hepatocellular Carcinoma Patients Treated With Sorafenib Reviewed

    Yamamoto Kenta, Kuzuya Teiji, Honda Takashi, Ito Takanori, Ishizu Yoji, Nakamura Masanao, Miyahara Ryoji, Kawashima Hiroki, Ishigami Masatoshi, Fujishiro Mitsuhiro

    ANTICANCER RESEARCH   Vol. 40 ( 2 ) page: 665 - 676   2020.2

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  99. Usefulness of Endoscopic Ultrasound Elastography Combined With the Strain Ratio in the Estimation of Treatment Effect in Autoimmune Pancreatitis Reviewed

    Ishikawa Takuya, Kawashima Hiroki, Ohno Eizaburo, Tanaka Hiroyuki, Maeda Keiko, Sawada Tsunaki, Yamamura Takeshi, Furukawa Kazuhiro, Nakamura Masanao, Miyahara Ryoji, Ishigami Masatoshi, Fujishiro Mitsuhiro

    PANCREAS   Vol. 49 ( 2 ) page: E21 - E22   2020.2

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  100. Color information from linked color imaging is associated with invasion depth and vascular diameter in superficial esophageal squamous cell carcinoma Reviewed International journal

    Kobayashi Kenichi, Miyahara Ryoji, Funasaka Kohei, Furukawa Kazuhiro, Sawada Tsunaki, Maeda Keiko, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Nakaguro Masato, Okumura Yuki, Hirooka Yoshiki, Fujishiro Mitsuhiro

    DIGESTIVE ENDOSCOPY   Vol. 32 ( 1 ) page: 65 - 73   2020.1

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    DOI: 10.1111/den.13469

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  101. Generation of magnifying endoscopic images of gastric neoplasms based on an all-in-focus algorithm Reviewed International journal

    Matsui Kenichi, Funasaka Kohei, Miyahara Ryoji, Furukawa Kazuhiro, Matsushita Masanobu, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Watanabe Osamu, Ohara Kenichi, Hirooka Yoshiki, Goto Hidemi

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 35 ( 1 ) page: 65 - 70   2020.1

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    DOI: 10.1111/jgh.14792

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  102. Decreased long-term graft survival in persistent biliary complications after right-lobe living-donor liver transplantation Reviewed International journal

    Ogiso Satoshi, Kamei Hideya, Onishi Yasuharu, Kurata Nobuhiko, Jobara Kanta, Kawashima Hiroki, Ogura Yasuhiro

    CLINICAL TRANSPLANTATION   Vol. 34 ( 1 ) page: e13771   2020.1

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    DOI: 10.1111/ctr.13771

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  103. A Prospective Study of Factors Associated with Abdominal Pain in Patients during Unsedated Colonoscopy Using a Magnifying Endoscope Reviewed International journal

    Suzuki Hiroto, Nakamura Masanao, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Takuya, Furukawa Kazuhiro, Ohno Eizaburo, Honda Takashi, Kawashima Hiroki, Ishigami Masatoshi, Fujishiro Mitsuhiro

    INTERNAL MEDICINE   Vol. 59 ( 15 ) page: 1795 - 1801   2020

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    DOI: 10.2169/internalmedicine.4267-19

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  104. Refractory Ulcerative Colitis Improved by Scheduled Combination Therapy of Vedolizumab and Granulocyte and Monocyte Adsorptive Apheresis Reviewed

    Nakamura Masanao, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Eri, Ohashi Ayako, Kajikawa Go, Furukawa Kazuhiro, Ohno Eizaburo, Honda Takashi, Kawashima Hiroki, Ishigami Masatoshi, Fujishiro Mitsuhiro

    INTERNAL MEDICINE   Vol. 59 ( 23 ) page: 3009 - 3014   2020

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  105. Nasal patency as a factor for successful transnasal endoscopy

    Nagaya Toshihiko, Miyahara Ryoji, Funasaka Kohei, Furukawa Kazuhiro, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Nakashima Tsutomu, Nakata Sciichi, Hirooka Yoshiki

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 81 ( 4 ) page: 587 - 595   2019.11

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  106. Feasibility and usefulness of endoscopic ultrasonography-guided shear-wave measurement for assessment of autoimmune pancreatitis activity: a prospective exploratory study Reviewed International journal

    Ohno Eizaburo, Hirooka Yoshiki, Kawashima Hiroki, Ishikawa Takuya, Tanaka Hiroyuki, Sakai Daisuke, Ishizu Yoji, Kuzuya Teiji, Nakamura Masanao, Honda Takashi

    JOURNAL OF MEDICAL ULTRASONICS   Vol. 46 ( 4 ) page: 425 - 433   2019.10

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    DOI: 10.1007/s10396-019-00944-4

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  107. Mucinous cystic neoplasm of the pancreas assessed with a real-time three-dimensional imaging using a transesophageal echocardiography probe

    Ishikawa Takuya, Hirooka Yoshiki, Kawashima Hiroki, Ohno Eizaburo, Fujishiro Mitsuhiro

    CLINICAL JOURNAL OF GASTROENTEROLOGY   Vol. 12 ( 5 ) page: 479 - 483   2019.10

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  108. Increased hardness of the underlying pancreas correlates with the presence of intraductal papillary-mucinous neoplasm in a limited number of cases Reviewed International journal

    Koya Toshinari, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Ishigami Masatoshi, Hashimoto Senju, Goto Hidemi, Hirooka Yoshiki

    JOURNAL OF MEDICAL ULTRASONICS   Vol. 46 ( 4 ) page: 441 - 447   2019.10

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    DOI: 10.1007/s10396-019-00956-0

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  109. Objective evaluation of the therapeutic effect of ustekinumab on Crohn's disease

    Yamamura T., Nakamura M., Murate K., Maeda K., Sawada T., Mizutani Y., Nishikawa T., Hattori S., Yamamoto K., Pu L. Zorron Cheng Tao, Ishikawa T., Furukawa K., Ohno E., Miyahara R., Kawashima H., Fujishiro M.

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 34   page: 145 - 145   2019.9

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  110. Specific members of gut microbiota predict mucosal healing in Crohn's disease

    Hattori S., Nakamura M., Yamamura T., Maeda K., Sawada T., Mizutani Y., Yamamoto K., Pu L. Zorron Cheng Tao, Honda T., Ishikawa T., Furukawa K., Ohno E., Miyahara R., Kawashima H., Fujishiro M.

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 34   page: 152 - 152   2019.9

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  111. Preoperative course of patients undergoing endoscopic nasobiliary drainage during the management of resectable perihilar cholangiocarcinoma Reviewed

    Maeda Takashi, Ebata Tomoki, Yokoyama Yukihiro, Mizuno Takashi, Yamaguchi Junpei, Onoe Shunsuke, Watanabe Nobuyuki, Kawashima Hiroki, Nagino Masato

    JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES   Vol. 26 ( 8 ) page: 341 - 347   2019.8

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    DOI: 10.1002/jhbp.640

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  112. THE PROPAGATION DISPLAY METHOD IMPROVES THE REPRODUCIBILITY OF PANCREATIC SHEAR WAVE ELASTOGRAPHY

    Hashizume Kiyotaka, Hirooka Yoshiki, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Kawai Manabu, Suhara Hiroki, Takeyama Tomoaki, Koya Toshinari, Tanaka Hiroyuki, Sakai Daisuke, Yamamura Takeshi, Furukawa Kazuhiro, Funasaka Kohei, Nakamura Masanao, Miyahara Ryoji, Watanabe Osamu, Ishigami Masatoshi, Kuwahara Takamichi, Hashimoto Senju, Goto Hidemi

    ULTRASOUND IN MEDICINE AND BIOLOGY   Vol. 45 ( 8 ) page: 2242 - 2247   2019.8

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  113. CLINICAL SIGNIFICANCE OF THE PATENCY OF GASTROINTESTINAL TRACT IN CROHN'S DISEASE EVALUATED BY PATENCY CAPSULE Reviewed International journal

    Nakamura Masanao, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Kuno Takeshi, Yamada Keisaku, Ishikawa Takuya, Furukawa Kazuhiro, Ohno Eizaburo, Miyahara Ryoji, Kawashima Hiroki, Hirooka Yoshiki

    GASTROINTESTINAL ENDOSCOPY   Vol. 89 ( 6 ) page: AB333 - AB333   2019.6

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  114. Regioselective Oxidative Ring Cleavage of Antiaromatic Nickel(II) Norcorrole to Dialkoxybis(dipyrrin)s

    Shafie Siham A., Kawashima Hiroyuki, Miyake Yoshihiro, Shinokubo Hiroshi

    CHEMPLUSCHEM   Vol. 84 ( 6 ) page: 623 - 626   2019.6

  115. USEFULNESS OF THE FORWARD-VIEWING RADIAL-ARRAY ECHOENDOSCOPE IN THE DIAGNOSIS OF INVASION DEPTH OF COLORECTAL NEOPLASIA

    Kuno Takeshi, Yamamura Takeshi, Nakamura Masanao, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Suzuki Hiroto, Esaki Masaya, Ishikawa Takuya, Furukawa Kazuhiro, Ohno Eizaburo, Kawashima Hiroki, Miyahara Ryoji, Hirooka Yoshiki

    GASTROINTESTINAL ENDOSCOPY   Vol. 89 ( 6 ) page: AB324 - AB324   2019.6

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  116. FACTORS RELATED TO MISSED COLORECTAL POLYPS ON COLON CAPSULE ENDOSCOPY IN CLINICAL PRACTICE Reviewed International journal

    Yamada Keisaku, Nakamura Masanao, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Niwa Yoshiki, Ishikawa Eri, Otsuka Hiroyuki, Suzuki Hiroto, Ishikawa Takuya, Furukawa Kazuhiro, Ohno Eizaburo, Miyahara Ryoji, Kawashima Hiroki, Hotta Naoki, Pu Leonardo Zorron Cheng Tao, Hirooka Yoshiki

    GASTROINTESTINAL ENDOSCOPY   Vol. 89 ( 6 ) page: AB155 - AB155   2019.6

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  117. USEFULLNESS OF EUS-GUIDED SHEAR-WAVE MEASUREMENT (EUS-SWM) FOR THE ASSESSMENT OF ACTIVITIES OF AUTOIMMUNE PANCREATITIS; A PROSPECTIVE EXPLORATORY STUDY

    Ohno Eizaburo, Hirooka Yoshiki, Kawashima Hiroki, Ishikawa Takuya, Tanaka Hiroyuki, Sakai Daisuke, Iida Tadashi, Nishio Ryo, Suzuki Hirotaka, Uetsuki Kota, Yashika Jun, Yamada Kenta, Yoshikawa Masakatsu, Gibo Noriaki, Aoki Toshinori, Yamamura Takeshi, Furukawa Kazuhiro, Nakamura Masanao, Miyahara Ryoji

    GASTROINTESTINAL ENDOSCOPY   Vol. 89 ( 6 ) page: AB608 - AB608   2019.6

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  118. The utility of ultrathin endoscopy with flexible spectral imaging color enhancement for early gastric cancer Reviewed

    Yokoyama Takafumi, Miyahara Ryoji, Funasaka Kohei, Furukawa Kazuhiro, Yamamura Takeshi, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Watanabe Osamu, Hirooka Yoshiki, Hirakawa Akihiro, Goto Hidemi

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 81 ( 2 ) page: 241 - 248   2019.5

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  119. Phase II study of chemoradiotherapy combined with gemcitabine plus nab-paclitaxel for unresectable locally advanced pancreatic ductal adenocarcinoma (NUPAT 05 Trial): study protocol for a single arm phase II study

    Takano Nao, Yamada Suguru, Hirakawa Akihiro, Yokoyama Yukihiro, Kawashima Hiroki, Maeda Osamu, Okada Tohru, Ohno Eizaburo, Yamaguchi Junpei, Ishikawa Takuya, Sonohara Fuminori, Suenaga Masaya, Takami Hideki, Hayashi Masamichi, Niwa Yukiko, Hirooka Yoshiki, Ito Yoshiyuki, Naganawa Shinji, Ando Yuichi, Nagino Masato, Goto Hidemi, Fuji Tsutomu, Kodera Yasuhiro

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 81 ( 2 ) page: 233 - 239   2019.5

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  120. Utility of linked color imaging for endoscopic diagnosis of early gastric cancer

    Fujiyoshi Toshihisa, Miyahara Ryoji, Funasaka Kohei, Furukawa Kazuhiro, Sawada Tsunaki, Maeda Keiko, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Nakaguro Masato, Nakatochi Masahiro, Hirooka Yoshiki

    WORLD JOURNAL OF GASTROENTEROLOGY   Vol. 25 ( 10 ) page: 1248 - 1258   2019.3

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  121. Transabdominal ultrasound elastography of the esophagogastric junction predicts reflux esophagitis

    Suhara Hiroki, Hirooka Yoshiki, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Nakamura Masanao, Miyahara Ryoji, Ishigami Masatoshi, Hashimoto Senju, Goto Hidemi

    JOURNAL OF MEDICAL ULTRASONICS   Vol. 46 ( 1 ) page: 99 - 104   2019.1

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  122. A Case of Plummer-Vinson Syndrome with Esophageal Web Formation in which Detailed Endoscopic Images Were Obtained. Reviewed

    Hirose T, Funasaka K, Furukawa K, Yamamura T, Ishikawa T, Ohno E, Nakamura M, Kawashima H, Miyahara R, Hirooka Y

    Internal medicine (Tokyo, Japan)   Vol. 58 ( 6 ) page: 785 - 789   2019

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    DOI: 10.2169/internalmedicine.1628-18

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  123. Clinical Impact of EUS-Guided Fine Needle Biopsy Using a Novel Franseen Needle for Histological Assessment of Pancreatic Diseases Reviewed International journal

    Ishikawa Takuya, Kawashima Hiroki, Ohno Eizaburo, Tanaka Hiroyuki, Sakai Daisuke, Iida Tadashi, Nishio Ryo, Yamamura Takeshi, Furukawa Kazuhiro, Nakamura Masanao, Miyahara Ryoji, Hashimoto Senju, Ishigami Masatoshi, Hirooka Yoshiki

    CANADIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 2019   page: 8581743   2019

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    DOI: 10.1155/2019/8581743

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  124. Lewis Score on Capsule Endoscopy as a Predictor of the Risk for Crohn's Disease-Related Emergency Hospitalization and Clinical Relapse in Patients with Small Bowel Crohn's Disease Reviewed

    Nishikawa Takahiro, Nakamura Masanao, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Takuya, Furukawa Kazuhiro, Ohno Eizaburo, Miyahara Ryoji, Kawashima Hiroki, Hirooka Yoshiki

    GASTROENTEROLOGY RESEARCH AND PRACTICE   Vol. 2019   page: 4274257   2019

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  125. Feasibility of EUS-guided shear-wave measurement: A preliminary clinical study Reviewed International journal

    Ohno Eizaburo, Hirooka Yoshiki, Kawashima Hiroki, Ishikawa Takuya

    ENDOSCOPIC ULTRASOUND   Vol. 8 ( 3 ) page: 215 - 216   2019

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    DOI: 10.4103/eus.eus_6_19

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  126. Randomized Phase II Study of Consecutive-Day versus Alternate-Day Treatment with S-1 as Second-Line Chemotherapy in Advanced Pancreatic Cancer

    Ishikawa Takuya, Kawashima Hiroki, Ohno Eizaburo, Matsubara Hiroshi, Sasaki Yoji, Achiwa Koichi, Kanamori Akira, Sumi Hajime, Hirai Takanori, Nonogaki Koji, Tsuzuki Tomoyuki, Kuroiwa Masanori, Hattori Masashi, Maruta Shinya, Hiramatsu Takeshi, Ando Masahiko, Hashimoto Senju, Hirooka Yoshiki

    ONCOLOGY   Vol. 96 ( 1 ) page: 1 - 7   2019

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  127. Validity of Capsule Endoscopy in Monitoring Therapeutic Interventions in Patients with Crohn's Disease

    Nakamura Masanao, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Takuya, Furukawa Kazuhiro, Ohno Eizaburo, Kawashima Hiroki, Miyahara Ryoji, Koulaouzidis Anastasios, Hirooka Yoshiki

    JOURNAL OF CLINICAL MEDICINE   Vol. 7 ( 10 )   2018.10

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  128. Clinical guidelines for primary sclerosing cholangitis 2017 Invited Reviewed International journal

    Isayama Hiroyuki, Tazuma Susumu, Kokudo Norihiro, Tanaka Atsushi, Tsuyuguchi Toshio, Nakazawa Takahiro, Notohara Kenji, Mizuno Suguru, Akamatsu Nobuhisa, Serikawa Masahiro, Naitoh Itaru, Hirooka Yoshiki, Wakai Toshifumi, Itoi Takao, Ebata Tomoki, Okaniwa Shinji, Kamisawa Terumi, Kawashima Hiroki, Kanno Atsushi, Kubota Keiichi, Tabata Masami, Unno Michiaki, Takikawa Hajime

    JOURNAL OF GASTROENTEROLOGY   Vol. 53 ( 9 ) page: 1006 - 1034   2018.9

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    DOI: 10.1007/s00535-018-1484-9

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  129. Effectiveness of a modified 6-Fr endoscopic nasobiliary drainage catheter for patients with preoperative perihilar cholangiocarcinoma. Reviewed International journal

    Kawashima H, Hirooka Y, Ohno E, Ishikawa T, Miyahara R, Watanabe O, Hayashi K, Ishigami M, Hashimoto S, Ebata T, Nagino M, Goto H

    Endoscopy international open   Vol. 6 ( 8 ) page: E1020 - E1030   2018.8

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    DOI: 10.1055/a-0614-2202

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  130. Neuroendocrine neoplasm of pancreas with cystic degeneration mimicking mucinous cystic neoplasm

    Kaosombatwattana Uayporn, Hirooka Yoshiki, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Suhara Hiroki, Goto Hidemi

    CLINICAL JOURNAL OF GASTROENTEROLOGY   Vol. 11 ( 4 ) page: 333 - 337   2018.8

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  131. Objective evaluation of blood flow in the small-intestinal villous: quantification of findings from dynamic endoscopy with concomitant narrow-band imaging

    Takeyama Tomoaki, Hirooka Yoshiki, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Yamamura Takeshi, Furukawa Kazuhiro, Funasaka Kohei, Nakamura Masanao, Miyahara Ryoji, Ishigami Masatoshi, Goto Hidemi

    ENDOSCOPY INTERNATIONAL OPEN   Vol. 6 ( 8 ) page: E941 - E949   2018.8

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  132. Increase in breath hydrogen concentration was correlated with the main pancreatic duct stenosis Reviewed International journal

    Sakai Daisuke, Hirooka Yoshiki, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Suhara Hiroki, Takeyama Tomoaki, Koya Toshinari, Tanaka Hiroyuki, Iida Tadashi, Nishio Ryo, Suzuki Hirotaka, Uetsuki Kota, Matsushita Masanobu, Yamamura Takeshi, Furukawa Kazuhiro, Funasaka Kohei, Nakamura Masanao, Miyahara Ryoji, Watanabe Osamu, Ishigami Masatoshi, Tsuruta Akihiro, Shin Woosuck, Goto Hidemi

    JOURNAL OF BREATH RESEARCH   Vol. 12 ( 3 ) page: 036004   2018.7

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    DOI: 10.1088/1752-7163/aaaf77

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  133. Measurements of renal shear wave velocities in chronic kidney disease patients Reviewed International journal

    Sasaki Yutaka, Hirooka Yoshiki, Kawashima Hiroki, Ishikawa Takuya, Takeshita Kyosuke, Goto Hidemi

    ACTA RADIOLOGICA   Vol. 59 ( 7 ) page: 884 - 890   2018.7

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    DOI: 10.1177/0284185117734417

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  134. DIAGNOSTIC IMAGING SYSTEM WITH VIRTUAL ENTEROSCOPY AND COMPUTER-AIDED DETECTION FOR EVALUATION OF SMALL BOWEL LESIONS OF CROHN'S DISEASE

    Furukawa Kazuhiro, Miyahara Ryoji, Funasaka Kohei, Suhara Hiroki, Matsushita Masanobu, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Watanabe Osamu, Oda Masahiro, Mori Kensaku, Hirooka Yoshiki, Goto Hidemi

    GASTROINTESTINAL ENDOSCOPY   Vol. 87 ( 6 ) page: AB304 - AB304   2018.6

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  135. PROSPECTIVE STUDY OF SMALL BOWEL CAPSULE ENDOSCOPY FOR EVALUATING THE THERAPEUTIC EFFECTS IN PATIENTS WITH CROHN'S DISEASE

    Nakamura Masanao, Hirooka Yoshiki, Watanabe Osamu, Yamamura Takeshi, Matsushita Masanobu, Suhara Hiroki, Ishikawa Takuya, Furukawa Kazuhiro, Funasaka Kohei, Ohno Eizaburo, Kawashima Hiroki, Miyahara Ryoji, Koulaouzidis Anastasios, Goto Hidemi

    GASTROINTESTINAL ENDOSCOPY   Vol. 87 ( 6 ) page: AB393 - AB393   2018.6

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  136. OUTCOMES AND PREDICTORS OF SEVERE SUBMUCOSAL FIBROSIS IN COLORECTAL ENDOSCOPIC SUBMUCOSAL DISSECTION

    Kaosombatwattana Uayporn, Yamamura Takeshi, Limsrivilai Julajak, Watanabe Osamu, Nakamura Masanao, Matsushita Masanobu, Suhara Hiroki, Ishikawa Takuya, Furukawa Kazuhiro, Funasaka Kohei, Ohno Eizaburo, Miyahara Ryoji, Kawashima Hiroki, Leelakusolvong Somchai, Hirooka Yoshiki, Goto Hidemi

    GASTROINTESTINAL ENDOSCOPY   Vol. 87 ( 6 ) page: AB377 - AB377   2018.6

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  137. EVALUATION OF LOCAL RECURRENCE AFTER COLD POLYPECTOMY COMPARED WITH CONVENTIONAL HOT POLYPECTOMY IN A PROSPECTIVE RANDOMIZED CONTROLLED TRIAL

    Yamamura Takeshi, Saito Masashi, Watanabe Osamu, Nakamura Masanao, Matsushita Masanobu, Sawada Tsunaki, Mizutani Yasuyuki, Niwa Yoshiki, Ishikawa Eri, Suzuki Hiroto, Otsuka Hiroyuki, Uchida Genta, Nishikawa Takahiro, Ishida Tetsuya, Kuno Takeshi, Yamada Keisaku, Hattori Shun, Hashiguchi Hiroki, Suhara Hiroki, Ishikawa Takuya, Furukawa Kazuhiro, Funasaka Kohei, Ohno Eizaburo, Miyahara Ryoji, Kawashima Hiroki, Hirooka Yoshiki, Goto Hidemi

    GASTROINTESTINAL ENDOSCOPY   Vol. 87 ( 6 ) page: AB478 - AB478   2018.6

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  138. ENDOSCOPIC TREATMENT FOR SUPERFICIAL NON-AMPULLARY DUODENAL TUMORS

    Furukawa Kazuhiro, Miyahara Ryoji, Funasaka Kohei, Suhara Hiroki, Matsushita Masanobu, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Watanabe Osamu, Hirooka Yoshiki, Goto Hidemi

    GASTROINTESTINAL ENDOSCOPY   Vol. 87 ( 6 ) page: AB315 - AB316   2018.6

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  139. THE DIAGNOSTIC ABILITY AND PITFALL OF JNET(JAPAN NBI EXPERT TEAM)CLASSIFICATION IN TRAINEES

    Suzuki Hiroto, Yamamura Takeshi, Watanabe Osamu, Nakamura Masanao, Matsushita Masanobu, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Eri, Niwa Yoshiki, Uchida Genta, Otsuka Hiroyuki, Nishikawa Takahiro, Ishida Tetsuya, Yamada Keisaku, Hattori Shun, Kajikawa Go, Hashiguchi Hiroki, Suhara Hiroki, Ishikawa Takuya, Furukawa Kazuhiro, Funasaka Kohei, Ohno Eizaburo, Kawashima Hiroki, Miyahara Ryoji, Hirooka Yoshiki, Goto Hidemi

    GASTROINTESTINAL ENDOSCOPY   Vol. 87 ( 6 ) page: AB489 - AB490   2018.6

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  140. USEFULNESS OF HISTOLOGICAL ASSESSMENT WITH EUS-GUIDED FINE NEEDLE BIOPSY USING A NEW CORE NEEDLE IN PANCREATIC DISEASES

    Ishikawa Takuya, Hirooka Yoshiki, Kawashima Hiroki, Ohno Eizaburo, Suhara Hiroki, Takeyama Tomoaki, Koya Toshinari, Tanaka Hiroyuki, Sakai Daisuke, Nishio Ryo, Iida Tadashi, Suzuki Hirotaka, Uetsuki Kota, Matsushita Masanobu, Yamamura Takeshi, Furukawa Kazuhiro, Funasaka Kohei, Nakamura Masanao, Miyahara Ryoji, Watanabe Osamu, Goto Hidemi

    GASTROINTESTINAL ENDOSCOPY   Vol. 87 ( 6 ) page: AB432 - AB433   2018.6

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  141. USEFULLNESS OF CONTRAST-ENHANCED HARMONIC EUS(CH-EUS) FOR THE PREOPERATIVE ASSESSMENT OF MPD INVOLVEMENT IN IPMN; A RETROSPECTIVE COMPARISON STUDY OF CH-EUS AND IDUS

    Ohno Eizaburo, Hirooka Yoshiki, Kawashima Hiroki, Ishikawa Takuya, Suhara Hiroki, Takeyama Tomoaki, Koya Toshinari, Tanaka Hiroyuki, Sakai Daisuke, Nishio Ryo, Iida Tadashi, Suzuki Hirotaka, Uetsuki Kota, Matsushita Masanobu, Furukawa Kazuhiro, Yamamura Takeshi, Funasaka Kohei, Nakamura Masanao, Miyahara Ryoji, Watanabe Osamu, Goto Hidemi

    GASTROINTESTINAL ENDOSCOPY   Vol. 87 ( 6 ) page: AB426 - AB427   2018.6

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  142. A Phase I clinical trial of EUS-guided intratumoral injection of the oncolytic virus, HF10 for unresectable locally advanced pancreatic cancer Reviewed International journal

    Hirooka Yoshiki, Kasuya Hideki, Ishikawa Takuya, Kawashima Hiroki, Ohno Eizaburo, Villalobos Itzel B., Naoe Yoshinori, Ichinose Toru, Koyama Nobuto, Tanaka Maki, Kodera Yasuhiro, Goto Hidemi

    BMC CANCER   Vol. 18 ( 1 ) page: 596   2018.5

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    DOI: 10.1186/s12885-018-4453-z

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  143. Fecal calprotectin reflects endoscopic activity in patients with small-bowel Crohn's disease according to double-balloon endoscopy findings Reviewed International journal

    Matsuura Rinzaburo, Watanabe Osamu, Nakamura Masanao, Yamamura Takeshi, Matsushita Masanobu, Suhara Hiroki, Furukawa Kazuhiro, Ishikawa Takuya, Funasaka Kohei, Ohno Eizaburo, Kawashima Hiroki, Miyahara Ryoji, Hirooka Yoshiki, Goto Hidemi

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 80 ( 2 ) page: 257 - 266   2018.5

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    DOI: 10.18999/nagjms.80.2.257

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  144. Phase I study of chemoradiotherapy using gemcitabine plus nab-paclitaxel for unresectable locally advanced pancreatic cancer

    Yamada Suguru, Fujii Tsutomu, Yokoyama Yukihiro, Kawashima Hiroki, Maeda Osamu, Suzuki Kojiro, Okada Tohru, Ono Eizaburo, Yamaguchi Junpei, Takano Nao, Takami Hideki, Hayashi Masamichi, Niwa Yukiko, Hirooka Yoshiki, Ito Yoshiyuki, Naganawa Shinji, Ando Yuichi, Nagino Masato, Goto Hidemi, Kodera Yasuhiro

    CANCER CHEMOTHERAPY AND PHARMACOLOGY   Vol. 81 ( 5 ) page: 815 - 821   2018.5

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  145. Nomogram-based prediction of rebleeding in small bowel bleeding patients: the 'PRSBB' score

    Uchida Genta, Hirooka Yoshiki, Nakamura Masanao, Watanabe Osamu, Yamamura Takeshi, Matsushita Masanobu, Suhara Hiroki, Ishikawa Takuya, Furukawa Kazuhiro, Funasaka Kohei, Ohno Eizaburo, Kawashima Hiroki, Miyahara Ryoji, Goto Hidemi

    SCIENTIFIC REPORTS   Vol. 8 ( 1 ) page: 6378   2018.4

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  146. Multiphase evaluation of contrast-enhanced endoscopic ultrasonography in the diagnosis of pancreatic solid lesions

    Ishikawa Takuya, Hirooka Yoshiki, Kawashima Hiroki, Ohno Eizaburo, Hashizume Kiyotaka, Funasaka Kohei, Nakamura Masanao, Miyahara Ryoji, Watanabe Osamu, Ishigami Masatoshi, Goto Hidemi

    PANCREATOLOGY   Vol. 18 ( 3 ) page: 291 - 297   2018.4

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    DOI: 10.1016/j.pan.2018.02.002

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  147. Usefulness of shear wave elastography as a quantitative diagnosis of chronic pancreatitis

    Kuwahara Takamichi, Hirooka Yoshiki, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Yamamura Takeshi, Furukawa Kazuhiro, Funasaka Kohei, Nakamura Masanao, Miyahara Ryoji, Watanabe Osamu, Ishigami Masatoshi, Hashimoto Senju, Goto Hidemi

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 33 ( 3 ) page: 756 - 761   2018.3

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  148. Clinical significance of gastrointestinal patency evaluation by using patency capsule in Crohn's disease Reviewed International journal

    Yoshimura Toru, Hirooka Yoshiki, Nakamura Masanao, Watanabe Osamu, Yamamura Takeshi, Matsushita Masanobu, Ishikawa Takuya, Furukawa Kazuhiro, Funasaka Kohei, Ohno Eizaburo, Kawashima Hiroki, Miyahara Ryoji, Goto Hidemi

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 80 ( 1 ) page: 121 - 128   2018.2

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    DOI: 10.18999/nagjms.80.1.121

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  149. Comparison of direct sequencing and Invader assay for Y93H mutation and response to interferon-free therapy in hepatitis C virus genotype 1b. Reviewed

    Hayashi K, Ishigami M, Ishizu Y, Kuzuya T, Honda T, Kawashima H, Ishikawa T, Tachi Y, Hattori M, Katano Y, Goto H, Hirooka Y.

    J Gastroenterol Hepatol.   Vol. 33 ( 1 ) page: 249-255   2018.1

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    DOI: 10.1111/jgh.13809.

  150. Natural history of pancreatic cystic lesions: A multicenter prospective observational study for evaluating the risk of pancreatic cancer. Reviewed

    Ohno E, Hirooka Y, Kawashima H, Ishikawa T, Kanamori A, Ishikawa H, Sasaki Y, Nonogaki K, Hara K, Hashimoto S, Matsubara H, Hirai T, Sumi H, Sugimoto H, Goto H; NSPINAL study group.

    J Gastroenterol Hepatol.   Vol. 33 ( 1 ) page: 320-328.   2018.1

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    DOI: 10.1111/jgh.13967.

  151. Comparison of direct sequencing and Invader assay for Y93H mutation and response to interferon-free therapy in hepatitis C virus genotype 1b Reviewed International journal

    Hayashi Kazuhiko, Ishigami Masatoshi, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Kawashima Hiroki, Ishikawa Tetsuya, Tachi Yoshihiko, Hattori Masashi, Katano Yoshiaki, Goto Hidemi, Hirooka Yoshiki

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 33 ( 1 ) page: 249 - 255   2018.1

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    DOI: 10.1111/jgh.13809

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  152. Natural history of pancreatic cystic lesions: A multicenter prospective observational study for evaluating the risk of pancreatic cancer

    Ohno Eizaburo, Hirooka Yoshiki, Kawashima Hiroki, Ishikawa Takuya, Kanamori Akira, Ishikawa Hideki, Sasaki Yoji, Nonogaki Koji, Hara Kazuo, Hashimoto Senju, Matsubara Hiroshi, Hirai Takanori, Sumi Hajime, Sugimoto Hiroyuki, Goto Hidemi

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 33 ( 1 ) page: 320 - 328   2018.1

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  153. Functional Correlation Between the Pancreas and the Small Intestine in Humans: The First Evaluation Using a Newly Developed Enteroscopy Reviewed International journal

    Hayashi Daijuro, Hirooka Yoshiki, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Kuwahara Takamichi, Kawai Manabu, Yamamura Takeshi, Furukawa Kazuhiro, Funasaka Kohei, Nakamura Masanao, Miyahara Ryoji, Watanabe Osamu, Ishigami Masatoshi, Hashimoto Senju, Goto Hidemi

    PANCREAS   Vol. 47 ( 5 ) page: 601 - 608   2018

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    DOI: 10.1097/MPA.0000000000001039

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  154. Fast Optical Circuit Switch Using Monolithically Integrated Silicon-Photonic Space Switch and Wavelength-Tuneable Filter

    Mori Yojiro, Ganbold Mungun-Erdene, Shiraki Ryuta, Suzuki Keijiro, Matsuura Hiroyuki, Kawashima Hitoshi, Namiki Shu, Ikeda Kazuhiro, Sato Ken-ichi

    2018 EUROPEAN CONFERENCE ON OPTICAL COMMUNICATION (ECOC)     2018

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  155. Usefulness of endoscopic ultrasonography-elastography as a predictive tool for the occurrence of pancreatic fistula after pancreatoduodenectomy.

    Kuwahara T, Hirooka Y, Kawashima H, Ohno E, Yokoyama Y, Fujii T, Nakamura S, Kodera Y, Nagino M, Goto H.

    J Hepatobiliary Pancreat Sci.   Vol. 24 ( 12 ) page: 649-656.   2017.12

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    DOI: 10.1002/jhbp.514.

  156. Usefulness of endoscopic ultrasonography-elastography as a predictive tool for the occurrence of pancreatic fistula after pancreatoduodenectomy

    Kuwahara Takamichi, Hirooka Yoshiki, Kawashima Hiroki, Ohno Eizaburo, Yokoyama Yukihiro, Fujii Tsutomu, Nakamura Shigeo, Kodera Yasuhiro, Nagino Masato, Goto Hidemi

    JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES   Vol. 24 ( 12 ) page: 649 - 656   2017.12

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    DOI: 10.1002/jhbp.514

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  157. Development and validation of a new scoring system to determine the necessity of small-bowel endoscopy in obscure gastrointestinal bleeding. Reviewed

    Uchida G, Nakamura M, Watanabe O, Yamamura T, Ishikawa T, Furukawa K, Funasaka K, Ohno E, Kawashima H, Miyahara R, Goto H, Hirooka Y.

    Dig Liver Dis.   Vol. 49 ( 11 ) page: 1218-1224   2017.11

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    DOI: 10.1016/j.dld.2017.08.036.

  158. Endoscopic ultrasound in diagnosis of solid pancreatic lesions: Elastography or contrast-enhanced harmonic alone versus the combination. Reviewed

    Chantarojanasiri T, Hirooka Y, Kawashima H, Ohno E, Kuwahara T, Yamamura T, Funasaka K, Nakamura M, Miyahara R, Ishigami M, Watanabe O, Hashimoto S, Hirakawa A, Ratanachu-Ek T, Goto H.

    Endosc Int Open.   Vol. 5 ( 11 ) page: E1136-E1143.   2017.11

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    DOI: 10.1055/s-0043-118829.

  159. Development and validation of a new scoring system to determine the necessity of small-bowel endoscopy in obscure gastrointestinal bleeding Reviewed International journal

    Uchida Genta, Nakamura Masanao, Watanabe Osamu, Yamamura Takeshi, Ishikawa Takuya, Furukawa Kazuhiro, Funasaka Kohei, Ohno Eizaburo, Kawashima Hiroki, Miyahara Ryoji, Goto Hidemi, Hirooka Yoshiki

    DIGESTIVE AND LIVER DISEASE   Vol. 49 ( 11 ) page: 1218 - 1224   2017.11

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    DOI: 10.1016/j.dld.2017.08.036

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  160. Endoscopic ultrasound in diagnosis of solid pancreatic lesions: Elastography or contrast-enhanced harmonic alone versus the combination Reviewed International coauthorship International journal

    Chantarojanasiri Tanyaporn, Hirooka Yoshiki, Kawashima Hiroki, Ohno Eizaburo, Kuwahara Takamichi, Yamamura Takeshi, Funasaka Kohei, Nakamura Masanao, Miyahara Ryoji, Ishigami Masatoshi, Watanabe Osamu, Hashimoto Senju, Hirakawa Akihiro, Ratanachu-ek Thawee, Goto Hidemi

    ENDOSCOPY INTERNATIONAL OPEN   Vol. 5 ( 11 ) page: E1136 - E1143   2017.11

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    DOI: 10.1055/s-0043-118829

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  161. In vivo histological diagnosis for gastric cancer using endocytoscopy. Reviewed

    Tsurudome I, Miyahara R, Funasaka K, Furukawa K, Matsushita M, Yamamura T, Ishikawa T, Ohno E, Nakamura M, Kawashima H, Watanabe O, Nakaguro M, Satou A, Hirooka Y, Goto H.

    World J Gastroenterol.   Vol. 23 ( 37 ) page: 6894-6901.   2017.10

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    DOI: 10.3748/wjg.v23.i37.6894.

  162. In vivo histological diagnosis for gastric cancer using endocytoscopy Reviewed International journal

    Tsurudome Issei, Miyahara Ryoji, Funasaka Kohei, Furukawa Kazuhiro, Matsushita Masanobu, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Watanabe Osamu, Nakaguro Masato, Satou Akira, Hirooka Yoshiki, Goto Hidemi

    WORLD JOURNAL OF GASTROENTEROLOGY   Vol. 23 ( 37 ) page: 6894 - 6901   2017.10

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    DOI: 10.3748/wjg.v23.i37.6894

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  163. Dexmedetomidine provides less body motion and respiratory depression during sedation in double-balloon enteroscopy than midazolam. Reviewed

    Oshima H, Nakamura M, Watanabe O, Yamamura T, Funasaka K, Ohno E, Kawashima H, Miyahara R, Goto H, Hirooka Y.

    SAGE Open Med.     2017.9

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    DOI: 10.1177/2050312117729920.

  164. Relational Joins on GPUs: A Closer Look

    Yabuta Makoto, Anh Nguyen, Kato Shinpei, Edahiro Masato, Kawashima Hideyuki

    IEEE TRANSACTIONS ON PARALLEL AND DISTRIBUTED SYSTEMS   Vol. 28 ( 9 ) page: 2663 - 2673   2017.9

  165. ETV1 expression would be a predictive marker of malignancy in GIST

    Funasaka Kohei, Miyahara Ryoji, Furukawa Kazuhiro, Matsushita Masanobu, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Watanabe Osamu, Hirooka Yoshiki, Goto Hidemi

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 32   page: 79 - 80   2017.9

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  166. Making decision to treat with infliximab by the result of periodic surveillance with double-balloon endoscopy after ilectomy can obtain mucosal healing and avoid re-operation on patients with Crohn's disease for a long-term follow-up study

    Watanabe Osamu, Nakamura Masanao, Yamamura Takeshi, Matsushita Masanobu, Saito Masashi, Matsuura Rinzaburou, Sawada Tsunaki, Mizutani Yasuyuki, Niwa Yoshiki, Ishikawa Eri, Uchida Genta, Otsuka Hiroyuki, Suzuki Hiroto, Nishikawa Takahiro, Ishida Tetsuya, Yamada Keishi, Kuno Takeshi, Hattori Shun, Ishikawa Takuya, Furukawa Kazuhiro, Funasaka Kohei, Ohno Eizaburo, Miyahara Ryoji, Kawashima Hiroki, Hirooka Yoshiki, Goto Hidemi

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 32   page: 287 - 287   2017.9

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  167. Clinical factors related to false-positive rates of patency capsule examination. Reviewed

    Sawada T, Nakamura M, Watanabe O, Yamamura T, Ishikawa T, Furukawa K, Funasaka K, Ohno E, Kawashima H, Miyahara R, Goto H, Hirooka Y.

    Therap Adv Gastroenterol.   Vol. 10 ( 8 ) page: 589-598.   2017.8

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  168. Usefulness of shear wave elastography as a quantitative diagnosis of chronic pancreatitis. Reviewed

    Usefulness of shear wave elastography as a quantitative diagnosis of chronic pancreatitis. Kuwahara T, Hirooka Y, Kawashima H, Ohno E, Ishikawa T, Yamamura T, Furukawa K, Funasaka K, Nakamura M, Miyahara R, Watanabe O, Ishigami M, Hashimoto S, Goto H.

    J Gastroenterol Hepatol.     2017.8

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    DOI: 10.1111/jgh.13926.

  169. Clinical factors related to false-positive rates of patency capsule examination Reviewed International journal

    Sawada Tsunaki, Nakamura Masanao, Watanabe Osamu, Yamamura Takeshi, Ishikawa Takuya, Furukawa Kazuhiro, Funasaka Kohei, Ohno Elzaburo, Kawashima Hiroki, Miyahara Ryoji, Goto Hidemi, Hirooka Yoshiki

    THERAPEUTIC ADVANCES IN GASTROENTEROLOGY   Vol. 10 ( 8 ) page: 589 - 598   2017.8

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    DOI: 10.1177/1756283X17722744

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  170. Quantitative diagnosis of chronic pancreatitis using EUS elastography. Reviewed

    Kuwahara T, Hirooka Y, Kawashima H, Ohno E, Ishikawa T, Kawai M, Suhara H, Takeyama T, Hashizume K, Koya T, Tanaka H, Sakai D, Yamamura T, Furukawa K, Funasaka K, Nakamura M, Miyahara R, Watanabe O, Ishigami M, Hashimoto S, Goto H.

    J Gastroenterol.   Vol. 52 ( 7 ) page: 868-874   2017.7

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    DOI: 10.1007/s00535-016-1296-8.

  171. Prospective multicenter phase II study of gemcitabine plus cisplatin in patients with unresectable gallbladder cancer. Reviewed

    Hirooka Y, Ishikawa T, Kawashima H, Ohno E, Nonogaki K, Kanamori A, Hirai T, Uchida H, Shirai O, Ishikawa H, Goto H.

    Cancer Chemother Pharmacol.   Vol. 80 ( 1 ) page: 119-125   2017.7

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    DOI: 10.1007/s00280-017-3341-6.

  172. Quantitative diagnosis of chronic pancreatitis using EUS elastography

    Kuwahara Takamichi, Hirooka Yoshiki, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Kawai Manabu, Suhara Hiroki, Takeyama Tomoaki, Hashizume Kiyotaka, Koya Toshinari, Tanaka Hiroyuki, Sakai Daisuke, Yamamura Takeshi, Furukawa Kazuhiro, Funasaka Kohei, Nakamura Masanao, Miyahara Ryoji, Watanabe Osamu, Ishigami Masatoshi, Hashimoto Senju, Goto Hidemi

    JOURNAL OF GASTROENTEROLOGY   Vol. 52 ( 7 ) page: 868 - 874   2017.7

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  173. Prospective multicenter phase II study of gemcitabine plus cisplatin in patients with unresectable gallbladder cancer

    Hirooka Yoshiki, Ishikawa Takuya, Kawashima Hiroki, Ohno Eizaburo, Nonogaki Koji, Kanamori Akira, Hirai Takanori, Uchida Hiroki, Shirai Osamu, Ishikawa Hideki, Goto Hidemi

    CANCER CHEMOTHERAPY AND PHARMACOLOGY   Vol. 80 ( 1 ) page: 119 - 125   2017.7

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  174. Clinical Factors Related to False Positive Rates of Patency Capsule Examination

    Sawada Tsunaki, Nakamura Masanao, Watanabe Osamu, Yamamura Takeshi, Matsushita Masanobu, Oshima Hiroshi, Sato Junichi, Saito Masashi, Matsuura Rinzaburo, Mizutani Yasuyuki, Niwa Yoshiki, Ishikawa Eri, Uchida Genta, Otsuka Hiroyuki, Suzuki Hiroto, Nishikawa Takahiro, Ishida Tetsuya, Ishikawa Takuya, Furukawa Kazuhiro, Funasaka Kohei, Ohno Eizaburo, Miyahara Ryoji, Kawashima Hiroki, Goto Hidemi, Hirooka Yoshiki

    GASTROINTESTINAL ENDOSCOPY   Vol. 85 ( 5 ) page: AB305 - AB305   2017.5

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  175. Predicting the Depth of Invasion of Esophageal Squamous Cell Carcinoma: Under Experience of Linked Colored Imaging With LED Light Source

    Kobayashi Kenichi, Miyahara Ryoji, Funasaka Kohei, Furukawa Kazuhiro, Matsushita Masanobu, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Watanabe Osamu, Hirooka Yoshiki, Goto Hidemi

    GASTROINTESTINAL ENDOSCOPY   Vol. 85 ( 5 ) page: AB527 - AB527   2017.5

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  176. One Year Follow-Up After Cold Polypectomy Compared With Hot Polypectomy for Small Colorectal Polyps - a Prospective Randomized Controlled Trial

    Saito Masashi, Yamamura Takeshi, Watanabe Osamu, Nakamura Masanao, Matsushita Masanobu, Oshima Hiroshi, Sato Junichi, Matsuura Rinzaburo, Mizutani Yasuyuki, Sawada Tsunaki, Niwa Yoshiki, Ishikawa Eri, Uchida Genta, Otsuka Hiroyuki, Suzuki Hiroto, Nishikawa Takahiro, Ishida Tetsuya, Ishikawa Takuya, Furukawa Kazuhiro, Funasaka Kohei, Ohno Eizaburo, Kawashima Hiroki, Miyahara Ryoji, Goto Hidemi, Hirooka Yoshiki

    GASTROINTESTINAL ENDOSCOPY   Vol. 85 ( 5 ) page: AB365 - AB366   2017.5

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  177. Objective Assessment of Jejunal Villous Blood Flow for Evaluating Pancreas-Jejunum Functional Correlation Using a Novel Image Analyzing System

    Takeyama Tomoaki, Hirooka Yoshiki, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Kawai Manabu, Suhara Hiroki, Hashizume Kiyotaka, Koya Toshinari, Tanaka Hiroyuki, Sakai Daisuke, Matsushita Masanobu, Yamamura Takeshi, Furukawa Kazuhiro, Funasaka Kohei, Nakamura Masanao, Miyahara Ryoji, Watanabe Osamu, Goto Hidemi

    GASTROINTESTINAL ENDOSCOPY   Vol. 85 ( 5 ) page: AB319 - AB320   2017.5

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  178. Novel EMR Technique for Preoperative Diagnosis and Treatment of Submucosal Tumor in the Small Bowel at Double-Balloon Endoscopy

    Nakamura Masanao, Watanabe Osamu, Yamamura Takeshi, Matsushita Masanobu, Oshima Hiroshi, Sato Junichi, Saito Masashi, Matsuura Rinzaburo, Mizutani Yasuyuki, Sawada Tsunaki, Niwa Yoshiki, Ishikawa Eri, Uchida Genta, Otsuka Hiroyuki, Suzuki Hiroto, Nishikawa Takahiro, Ishida Tetsuya, Ishikawa Takuya, Furukawa Kazuhiro, Funasaka Kohei, Ohno Eizaburo, Kawashima Hiroki, Miyahara Ryoji, Goto Hidemi, Hirooka Yoshiki

    GASTROINTESTINAL ENDOSCOPY   Vol. 85 ( 5 ) page: AB300 - AB300   2017.5

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  179. Establishment of a New Scoring System for Predicting the Necessity of Double-Balloon Endoscopy in Obscure Gastrointestinal Bleeding

    Uchida Genta, Watanabe Osamu, Nakamura Masanao, Yamamura Takeshi, Matsushita Masanobu, Oshima Hiroshi, Sato Junichi, Saito Masashi, Matsuura Rinzaburo, Mizutani Yasuyuki, Sawada Tsunaki, Niwa Yoshiki, Ishikawa Eri, Otsuka Hiroyuki, Suzuki Hiroto, Nishikawa Takahiro, Ishida Tetsuya, Ishikawa Takuya, Furukawa Kazuhiro, Funasaka Kohei, Ohno Eizaburo, Kawashima Hiroki, Miyahara Ryoji, Goto Hidemi, Hirooka Yoshiki

    GASTROINTESTINAL ENDOSCOPY   Vol. 85 ( 5 ) page: AB300 - AB300   2017.5

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  180. The Outcome of Treatment in Hypopharyngeal and Cervical Esophageal Carcinoma

    Fujiyoshi Toshihisa, Miyahara Ryoji, Funasaka Kohei, Furukawa Kazuhiro, Matsushita Masanobu, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Watanabe Osamu, Hirooka Yoshiki, Goto Hidemi

    GASTROINTESTINAL ENDOSCOPY   Vol. 85 ( 5 ) page: AB597 - AB598   2017.5

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  181. The Study of Diagnostic Ability for the Colorectal Neoplasms by Imaged Enhanced Endoscopy Using by JNET (Japan NBI Expert Team) Classification

    Yamamura Takeshi, Watanabe Osamu, Nakamura Masanao, Matsushita Masanobu, Oshima Hiroshi, Sato Junichi, Matsuura Rinzaburo, Saito Masashi, Mizutani Yasuyuki, Sawada Tsunaki, Niwa Yoshiki, Ishikawa Eri, Uchida Genta, Otsuka Hiroyuki, Suzuki Hiroto, Nishikawa Takahiro, Ishida Tetsuya, Ishikawa Takuya, Furukawa Kazuhiro, Funasaka Kohei, Ohno Eizaburo, Kawashima Hiroki, Miyahara Ryoji, Hirooka Yoshiki, Goto Hidemi

    GASTROINTESTINAL ENDOSCOPY   Vol. 85 ( 5 ) page: AB402 - AB402   2017.5

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  182. Analysis of the risk factors for severity in post endoscopic retrograde cholangiopancreatography pancreatitis: The indication of prophylactic treatments Reviewed International journal

    Matsubara Hiroshi, Urano Fumihiro, Kinoshita Yuki, Okamura Shozo, Kawashima Hiroki, Goto Hidemi, Hirooka Yoshiki

    WORLD JOURNAL OF GASTROINTESTINAL ENDOSCOPY   Vol. 9 ( 4 ) page: 189 - 195   2017.4

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    DOI: 10.4253/wjge.v9.i4.189

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  183. Comparison of the diagnostic ability of blue laser imaging magnification versus pit pattern analysis for colorectal polyps. Reviewed

    Nakano A, Hirooka Y, Yamamura T, Watanabe O, Nakamura M, Funasaka K, Ohno E, Kawashima H, Miyahara R, Goto H.

    Endosc Int Open.   Vol. 5 ( 4 ) page: E224-E231   2017.4

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    DOI: 10.1055/s-0043-102400.

  184. Analysis of the risk factors for severity in post endoscopic retrograde cholangiopancreatography pancreatitis: The indication of prophylactic treatments. Reviewed

    Matsubara H, Urano F, Kinoshita Y, Okamura S, Kawashima H, Goto H, Hirooka Y.

    World J Gastrointest Endosc.   Vol. 9 ( 4 ) page: 189-195   2017.4

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    DOI: 10.4253/wjge.v9.i4.189.

  185. Comparison of the diagnostic ability of blue laser imaging magnification versus pit pattern analysis for colorectal polyps Reviewed International journal

    Nakano Arihiro, Hirooka Yoshiki, Yamamura Takeshi, Watanabe Osamu, Nakamura Masanao, Funasaka Kohei, Ohno Eizaburo, Kawashima Hiroki, Miyahara Ryoji, Goto Hidemi

    ENDOSCOPY INTERNATIONAL OPEN   Vol. 5 ( 4 ) page: E224 - E231   2017.4

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    DOI: 10.1055/s-0043-102400

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  186. Measurements of renal shear wave velocities in chronic kidney disease patients. Reviewed

    Sasaki Y, Hirooka Y, Kawashima H, Ishikawa T, Takeshita K, Goto H.

    Acta Radiol.     2017.1

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    DOI: 10.1177/0284185117734417.

  187. Prospective study of factors important to achieve observation of the entire colon on colon capsule endoscopy. Reviewed

    Sato J, Nakamura M, Watanabe O, Yamamura T, Funasaka K, Ohno E, Miyahara R, Kawashima H, Goto H, Hirooka Y.

    Therap Adv Gastroenterol.   Vol. 10 ( 1 ) page: 20-31.   2017.1

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    DOI: 10.1177/1756283X16673556.

  188. Specific characteristics of hemorrhagic Meckel's diverticulum at double-balloon endoscopy. Reviewed

    Mizutani Y, Nakamura M, Watanabe O, Yamamura T, Funasaka K, Ohno E, Kawashima H, Miyahara R, Murino A, Goto H Professor, Hirooka Y.

    Endosc Int Open.   Vol. 5 ( 1 ) page: E35-E40   2017.1

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    DOI: 10.1055/s-0042-119810.

  189. Prospective study of factors important to achieve observation of the entire colon on colon capsule endoscopy

    Sato Junichi, Nakamura Masanao, Watanabe Osamu, Yamamura Takeshi, Funasaka Kohei, Ohno Eizaburo, Miyahara Ryoji, Kawashima Hiroki, Goto Hidemi, Hirooka Yoshiki

    THERAPEUTIC ADVANCES IN GASTROENTEROLOGY   Vol. 10 ( 1 ) page: 20 - 31   2017.1

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  190. Specific characteristics of hemorrhagic Meckel's diverticulum at double-balloon endoscopy

    Mizutani Yasuyuki, Nakamura Masanao, Watanabe Osamu, Yamamura Takeshi, Funasaka Kohei, Ohno Eizaburo, Kawashima Hiroki, Miyahara Ryoji, Murino Alberto, Goto Hidemi, Hirooka Yoshiki

    ENDOSCOPY INTERNATIONAL OPEN   Vol. 5 ( 1 ) page: E35 - E40   2017.1

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  191. The role of endoscopic ultrasound in the diagnosis of gallbladder diseases

    Chantarojanasiri Tanyaporn, Hirooka Yoshiki, Kawashima Hiroki, Ohno Eizaburo, Kongkam Pradermchai, Goto Hidemi

    JOURNAL OF MEDICAL ULTRASONICS   Vol. 44 ( 1 ) page: 63 - 70   2017.1

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  192. Endoscopic Characteristics, Risk Grade, and Prognostic Prediction in Gastrointestinal Stromal Tumors of the Small Bowel. Reviewed

    Nakano A, Nakamura M, Watanabe O, Yamamura T, Funasaka K, Ohno E, Kawashima H, Miyahara R, Goto H, Hirooka Y.

    Digestion.   Vol. 95 ( 2 ) page: 122-131   2017

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    DOI: 10.1159/000454728.

  193. Dexmedetomidine provides less body motion and respiratory depression during sedation in double-balloon enteroscopy than midazolam Reviewed International journal

    Oshima Hiroshi, Nakamura Masanao, Watanabe Osamu, Yamamura Takeshi, Funasaka Kohei, Ohno Eizaburo, Kawashima Hiroki, Miyahara Ryoji, Goto Hidemi, Hirooka Yoshiki

    SAGE OPEN MEDICINE   Vol. 5   page: 2050312117729920   2017

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    DOI: 10.1177/2050312117729920

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  194. Endoscopic Characteristics, Risk Grade, and Prognostic Prediction in Gastrointestinal Stromal Tumors of the Small Bowel Reviewed International journal

    Nakano Arihiro, Nakamura Masanao, Watanabe Osamu, Yamamura Takeshi, Funasaka Kohei, Ohno Eizaburo, Kawashima Hiroki, Miyahara Ryoji, Goto Hidemi, Hirooka Yoshiki

    DIGESTION   Vol. 95 ( 2 ) page: 122 - 131   2017

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    DOI: 10.1159/000454728

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  195. Risk factors for rebleeding and risk-based follow-up of obscure gastrointestinal bleeding after its initial diagnosis.

    Uchida G, Nakamura M, Watanabe O, Yamamura T, Matsushita M, Ishikawa T, Furukawa K, Funasaka K, Ohno E, Kawashima H, Miyahara R, Goto H, Hirooka Y

    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology   Vol. 114 ( 10 ) page: 1819 - 1829   2017

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    DOI: 10.11405/nisshoshi.114.1819

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  196. Diagnostic and Therapeutic Endoscopic Retrograde Cholangiography Using a Short-Type Double-Balloon Endoscope in Patients With Altered Gastrointestinal Anatomy: A Multicenter Prospective Study in Japan. Reviewed

    Shimatani M, Hatanaka H, Kogure H, Tsutsumi K, Kawashima H, Hanada K, Matsuda T, Fujita T, Takaoka M, Yano T, Yamada A, Kato H, Okazaki K, Yamamoto H, Ishikawa H, Sugano K; Japanese DB-ERC Study Group.

    Am J Gastroenterol.   Vol. 111 ( 12 ) page: 1750-1758   2016.12

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    DOI: 10.1038/ajg.2016.420.

  197. Quantitative evaluation of pancreatic tumor fibrosis using shear wave elastography. Reviewed

    Kuwahara T, Hirooka Y, Kawashima H, Ohno E, Sugimoto H, Hayashi D, Morishima T, Kawai M, Suhara H, Takeyama T, Yamamura T, Funasaka K, Nakamura M, Miyahara R, Watanabe O, Ishigami M, Shimoyama Y, Nakamura S, Hashimoto S, Goto H.

    Pancreatology.   Vol. 16 ( 6 ) page: 1063-1068   2016.11

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    DOI: 10.1016/j.pan.2016.09.012.

  198. Endoscopic ultrasound in the diagnosis of acinar cell carcinoma of the pancreas: contrast-enhanced endoscopic ultrasound, endoscopic ultrasound elastography, and pathological correlation. Reviewed

    Chantarojanasiri T, Hirooka Y, Kawashima H, Ohno E, Yamamura T, Funasaka K, Nakamura M, Miyahara R, Ishigami M, Watanabe O, Nakaguro M, Shimoyama Y, Nakamura S, Goto H.

    Endosc Int Open.   Vol. 41 ( 11 ) page: E1223-E1226   2016.11

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  199. Endoscopic ultrasound in the diagnosis of acinar cell carcinoma of the pancreas: contrast-enhanced endoscopic ultrasound, endoscopic ultrasound elastography, and pathological correlation. Reviewed

    Chantarojanasiri T, Hirooka Y, Kawashima H, Ohno E, Yamamura T, Funasaka K, Nakamura M, Miyahara R, Ishigami M, Watanabe O, Nakaguro M, Shimoyama Y, Nakamura S, Goto H.

    Endosc Int Open.   Vol. 4 ( 11 ) page: E1223-E1226   2016.11

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  200. Prospective multicenter study on the usefulness of EUS-guided FNA biopsy for the diagnosis of autoimmune pancreatitis. Reviewed

    Morishima T, Kawashima H, Ohno E, Yamamura T, Funasaka K, Nakamura M, Miyahara R, Watanabe O, Ishigami M, Shimoyama Y, Nakamura S, Hashimoto S, Goto H, Hirooka Y.

    Gastrointest Endosc.   Vol. 84 ( 2 ) page: 241-248   2016.8

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    DOI: 10.1016/j.gie.2016.01.016.

  201. The prognostic factors and trajectory of HRQOL in patients with pancreatic cancer who received psychiatric intervention. Reviewed

    Sugimoto H, Kawashima H, Ohno E, Hayashi D, Kuwahara T, Morishima T, Kawai M, Suhara H, Takeyama T, Yamamura T, Funasaka K, Nakamura M, Miyahara R, Watanabe O, Ishigami M, Suzuki M, Kimura H, Ozaki N, Hashimoto S, Goto H, Hirooka Y.

    J Gastroenterol Hepatol.   Vol. 31 ( 3 ) page: 685-690   2016.3

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    DOI: 10.1111/jgh.13172.

  202. Endoscopic Closure of Duodenal Perforation with the Over-the-scope-clipping System. Reviewed

    Furukawa K, Miyahara R, Funasaka K, Yamamura T, Ohno E, Nakamura M, Kawashima H, Watanabe O, Hirooka Y, Goto H.

    Intern Med.   Vol. 55 ( 21 ) page: 3131-3135   2016

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  203. Reply to Letter: "Preoperative Endoscopic Nasobiliary Drainage in Patients With Suspected Hilar Cholangiocarcinoma; Better Than Endoscopic or Percutaneous Biliary Drainage?". Reviewed

    Kawashima H, Itoh A, Ohno E, Itoh Y, Ebata T, Nagino M, Goto H, Hirooka Y

    Annals of surgery   Vol. 262 ( 2 ) page: e55-6   2015.8

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    DOI: 10.1097/SLA.0000000000000822

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  204. Current status of tissue harmonic imaging in endoscopic ultrasonography (EUS) and EUS-elastography in pancreatobiliary diseases. Reviewed

    Ohno E, Kawashima H, Hashimoto S, Goto H, Hirooka Y

    Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society   Vol. 27 Suppl 1   page: 68-73   2015.4

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    DOI: 10.1111/den.12433

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  205. Usefulness and safety of endoscopic retrograde cholangiopancreatography in children with pancreaticobiliary maljunction. Reviewed

    Hiramatsu T, Itoh A, Kawashima H, Ohno E, Itoh Y, Sugimoto H, Sumi H, Funasaka K, Nakamura M, Miyahara R, Katano Y, Ishigami M, Ohmiya N, Kaneko K, Ando H, Goto H, Hirooka Y.

    J Pediatr Surg.   Vol. 50 ( 3 ) page: 377-381   2015.3

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    DOI: 10.1016/j.jpedsurg.2014.08.024.

  206. Simplified magnetic anchor-guided endoscopic submucosal dissection in dogs (with videos). Reviewed

    Matsuzaki I, Miyahara R, Hirooka Y, Funasaka K, Furukawa K, Ohno E, Nakamura M, Kawashima H, Maeda O, Watanabe O, Ando T, Kobayashi M, Goto H

    Gastrointestinal endoscopy   Vol. 80 ( 4 ) page: 712-6   2014.10

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    DOI: 10.1016/j.gie.2014.05.334

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  207. Preliminary study on evaluation of the pancreatic tail observable limit of transabdominal ultrasonography using a position sensor and CT-fusion image. Reviewed

    Sumi H, Itoh A, Kawashima H, Ohno E, Itoh Y, Nakamura Y, Hiramatsu T, Sugimoto H, Hayashi D, Kuwahara T, Morishima T, Kawai M, Furukawa K, Funasaka K, Nakamura M, Miyahara R, Katano Y, Ishigami M, Ohmiya N, Goto H, Hirooka Y.

    Eur J Radiol.   Vol. 83 ( 8 ) page: 1324-31   2014.8

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  208. Three cases with active bleeding from radiation enteritis that were diagnosed with video capsule endoscopy without retention. Reviewed

    Nakamura M, Hirooka Y, Watanabe O, Yamamura T, Furukawa K, Funasaka K, Ohno E, Miyahara R, Kawashima H, Ando T, Ohmiya N, Goto H

    Nagoya journal of medical science   Vol. 76 ( 3-4 ) page: 369-74   2014.8

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  209. Phase I Dose-escalation Clinical Trial of HF10 Oncolytic Herpes Virus in 17 Japanese Patients with Advanced Cancer. Reviewed

    Kasuya H, Kodera Y, Nakao A, Yamamura K, Gewen T, Zhiwen W, Hotta Y, Yamada S, Fujii T, Fukuda S, Tsurumaru N, Kuwahara T, Kikumori T, Koide Y, Fujimoto Y, Nakashima T, Hirooka Y, Shiku H, Tanaka M, Takesako K, Kondo T, Aleksic B, Kawashima H, Goto H, Nishiyama Y

    Hepato-gastroenterology   Vol. 61 ( 131 ) page: 599-605   2014.5

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  210. Impact of instrument channel diameter on therapeutic endoscopic retrograde cholangiography using balloon-assisted enteroscopy. Reviewed

    Kawashima H, Nakamura M, Ohno E, Goto H, Hirooka Y.

    Dig Endosc.   Vol. 26 ( S2 ) page: 127-129   2014.4

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    DOI: 10.1111/den.12262.

  211. Extraluminal GI stromal tumor of the jejunum diagnosed by EUS at double-balloon endoscopy. Reviewed

    Nakamura M, Ohmiya N, Hirooka Y, Kawashima H, Yamamura T, Ishihara M, Yamada K, Nagura A, Yoshimura T, Miyahara R, Funasaka K, Itoh A, Ohno E, Ando T, Watanabe O, Uehara K, Yoshioka Y, Nagino M, Goto H

    Gastrointestinal endoscopy   Vol. 79 ( 2 ) page: 335-6   2014.2

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    DOI: 10.1016/j.gie.2013.09.016

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  212. Should plastic stents be avoided in all unresectable malignant perihilar biliary strictures? Reviewed

    Kawashima H, Itoh A, Ohno E, Goto H, Hirooka Y.

    Dig Endosc.   Vol. 25 ( S2 ) page: 86-89   2013.5

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    DOI: 10.1111/den.12088.

  213. Preoperative Endoscopic Nasobiliary Drainage in 164 Consecutive Patients With Suspected Perihilar Cholangiocarcinoma: A Retrospective Study of Efficacy and Risk Factors Related to Complications. Reviewed

    Kawashima H, Itoh A, Ohno E, Itoh Y, Ebata T, Nagino M, Goto H, Hirooka Y

    Ann surg   Vol. 257 ( 1 ) page: 121-127   2013.1

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    DOI: doi: 10.1097/SLA.0b013e318262b2e9.

  214. Diagnostic and prognostic value of immunohistochemical expression of S100P and IMP3 in transpapillary biliary forceps biopsy samples of extrahepatic bile duct carcinoma. Reviewed

    Kawashima H, Itoh A, Ohno E, Miyahara R, Ohmiya N, Tanaka T, Shimoyama Y, Nakamura S, Ebata T, Nagino M, Goto H, Hirooka Y.

    J Hepatobiliary Pancreat Sci.     page: 1   2012.12

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  215. Transpapillary biliary forceps biopsy to distinguish benign biliary stricture from malignancy: how many tissue samples should be obtained? Invited Reviewed

    Kawashima H, Itoh A, Ohno E, Goto H, Hirooka Y.

    Dig Endosc   Vol. 24 ( supple1 ) page: 22-27   2012.5

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    DOI: doi: 10.1111/j.1443-1661.2012.01253.x.

  216. 膵・胆管合流異常の診断にはどの検査法がいいのか? 腹部超音波検査(US)、超音波内視鏡検査(EUS)、管腔内超音波検査(IDUS)の膵・胆管合流異常診断に対する役割 Invited

    川嶋啓揮, 廣岡芳樹, 伊藤彰浩, 大野栄三郎, 伊藤裕也, 中村陽介, 平松武, 杉本啓之, 鷲見肇, 宮原良二, 大宮直木, 後藤秀実

    胆と膵   Vol. 33 ( 1 ) page: 23-26   2012.1

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  217. Prospective multicenter study to investigate the introduction rate of second-line S-1 in gemcitabine-refractory unresectable pancreatic cancer. Reviewed

    Kawashima H, Itoh A, Ohno E, Nakamura M, Miyahara R, Ohmiya N, Hara K, Kanamori A, Itoh T, Taki T, Hirai T, Hashimoto S, Takeda K, Goto H, Hirooka Y.

    Cancer Chemother Pharmacol.   Vol. 68 ( 3 ) page: 677-83   2011.9

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  218. Dynamic Quantitative Evaluation of Contrast-Enhanced Endoscopic Ultrasonography in the Diagnosis of Pancreatic Diseases. Reviewed

    Matsubara H, Itoh A, Kawashima H, Kasugai T, Ohno E, Ishikawa T, Itoh Y, Nakamura Y, Hiramatsu T, Nakamura M, Miyahara R, Ohmiya N, Ishigami M, Katano Y, Goto H, Hirooka Y.

    Pancreas.     page: Epub ahead of print   2011.5

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  219. Clinical oncology for pancreatic and biliary cancers: Advances and current limitations. Invited Reviewed

    Hirooka Y, Itoh A, Kawashima H, Ohno E, Ishikawa T, Itoh Y, Nakamura Y, Hiramatsu T, Nakamura M, Miyahara R, Ohmiya N, Ishigami M, Katano Y, Goto H.

    World J Clin Oncol.   Vol. 2 ( 5 ) page: 217-24   2011.5

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  220. P53, p21, and p73 gene polymorphisms in gastric carcinoma. Reviewed

    Shirai O, Ohmiya N, Taguchi A, Nakamura M, Kawashima H, Miyahara R, Itoh A, Hirooka Y, Watanabe O, Ando T, Goto Y, Hamajima N, Goto H.

    Hepatogastroenterology.   Vol. 57 ( 104 ) page: 1595-601.   2010.11

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  221. 特集 胆膵EUS-FNAのエビデンス2010切除不能局所進行膵癌に対するゲムシタビンとEUS下樹状細胞局注療法の作用治療 Invited

    廣岡芳樹、伊藤彰浩、川嶋啓揮、大野栄三郎、石川卓哉、松原浩、伊藤裕也、中村陽介、平松武、中村正直、宮原良二、大宮直木、石上雅敏、片野義明、金子享、後藤重則、高原将司、後藤秀実、

    胆と膵   Vol. 31 ( 10 ) page: 1245-1248   2010.11

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  222. 《腫瘍性病変における内視鏡診療の進歩》十二指腸腫瘍-乳頭部腫瘍を中心に- Invited

    伊藤彰浩、廣岡芳樹、川嶋啓揮、大野栄三郎、石川卓哉、後藤秀実

    内科   Vol. 106 ( 4 ) page: 638-642   2010.10

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  223. Is nasobiliary drainage unnecessary for drainage of acute suppurative cholangitis? Our experience Invited Reviewed

    Kawashima H, Itoh A, Ohno E, Goto H, Hirooka Y

    Dig Endosc.   Vol. 22 ( supple1 ) page: 118-122   2010.7

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  224. Usefulness of EUS combined with contrast-enhancement in the differential diagnosis of malignant versus benign and preoperative localization of pancreatic endocrine tumors. Reviewed

    Ishikawa T, Itoh A, Kawashima H, Ohno E, Matsubara H, Itoh Y, Nakamura Y, Nakamura M, Miyahara R, Hayashi K, Ishigami M, Katano Y, Ohmiya N, Goto H, Hirooka Y.

    Gastrointest Endosc.   Vol. 71 ( 6 ) page: 951-9   2010.5

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  225. 【消化器疾患の画像診断[放射線・MRI・超音波] スタンダードから新しい診断技術】 新しい肝・胆・膵の画像診断 膵臓疾患におけるUS elastography Invited

    内田博起, 廣岡芳樹, 飯塚昭男, 川嶋啓揮, 伊藤彰浩, 後藤秀実

    臨床消化器内科   Vol. 25 ( 7 ) page: 1020-1025   2010.5

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  226. 【胆管狭窄に迫る 悪性との鑑別が問題となる良性胆管狭窄】 胆管狭窄良悪性の鑑別診断 画像でどこまでわかるか? EUS・IDUS Invited

    松原浩, 廣岡芳樹, 伊藤彰浩, 川嶋啓揮, 大野栄三郎, 石川卓哉, 伊藤裕也, 中村陽介, 平松武, 後藤秀実

    肝胆膵画像   Vol. 12 ( 3 ) page: 317-324   2010.5

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  227. A preliminary result of three-dimensional microarray technology to gene analysis with endoscopic ultrasound-guided fine-needle aspiration specimens and pancreatic juices. Reviewed

    Nonogaki K, Itoh A, Kawashima H, Ohno E, Ishikawa T, Matsubara H, Itoh Y, Nakamura Y, Nakamura M, Miyahara R, Ohmiya N, Ishigami M, Katano Y, Goto H, Hirooka Y.

    J Exp Clin Cancer Res.     page: 29-36   2010.4

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  228. 【胆道癌の進展度診断と治療戦略】 経乳頭的胆管生検による胆管癌表層進展範囲診断 Invited

    川嶋啓揮, 廣岡芳樹, 伊藤彰浩, 大野栄三郎, 石川卓哉, 松原浩, 伊藤裕也, 中村陽介, 中村正直, 宮原良二, 大宮直木, 後藤秀実

    消化器内科   Vol. 50 ( 2 ) page: 180-183   2010.2

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  229. 【自己免疫性膵炎・長期予後】 自己免疫性膵炎の長期的変化 自己免疫性膵炎における膵機能の長期的変化 Invited

    石川卓哉, 廣岡芳樹, 伊藤彰浩, 川嶋啓揮, 大野栄三郎, 松原浩, 伊藤裕也, 中村正直, 宮原良二, 大宮直木, 丹羽康正, 後藤秀実

    肝・胆・膵   Vol. 60 ( 1 ) page: 75-78   2010.1

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  230. 重複胆管の1例 Reviewed

    石川卓哉, 廣岡芳樹, 伊藤彰浩, 川嶋啓揮, 丹羽康正, 後藤秀実

    胆道   Vol. 23 ( 5 ) page: 797-805   2009.12

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  231. 【胆膵治療内視鏡のエキスパートテクニック】 ERCP関連手技 主(副)乳頭に対するアプローチ 十二指腸乳頭切除術 Invited

    伊藤彰浩, 廣岡芳樹, 川嶋啓揮, 大野栄三郎, 石川卓哉, 松原浩, 伊藤裕也, 後藤秀実

    胆と膵   Vol. 30   page: 1181-1185   2009.10

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  232. 【胆膵治療内視鏡のエキスパートテクニック】 EUS関連手技 切除不能局所進行膵癌に対するEUS下樹状細胞局注療法 Invited

    廣岡芳樹, 伊藤彰浩, 川嶋啓揮, 大野栄三郎, 石川卓哉, 松原浩, 伊藤裕也, 中村陽介, 中村正直, 宮原良二, 大宮直木, 石上雅敏, 片野義明, 金子亨, 後藤重則, 後藤秀実

    胆と膵   Vol. 30   page: 1257-1261   2009.10

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

  233. 良性胆管狭窄診断に対する経乳頭的胆管生検の有用性 Invited

    川嶋啓揮, 廣岡芳樹, 伊藤彰浩, 大野栄三郎, 石川卓哉, 松原浩, 伊藤裕也, 中村正直, 宮原良二, 大宮直木, 丹羽康正, 後藤秀実

    胆と膵   Vol. 30 ( 8 ) page: 849-853   2009.8

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  234. 【胆膵疾患におけるUS/EUS診断・治療の最前線】 膵臓疾患に対する超音波エラストグラフィーの有用性 Invited

    廣岡芳樹, 伊藤彰浩, 川嶋啓揮, 大野栄三郎, 石川卓哉, 松原浩, 伊藤裕也, 中村正直, 宮原良二, 大宮直木, 丹羽康正, 後藤秀実, 内田博起, 春日井俊史

    胆と膵   Vol. 30 ( 7 ) page: 715-721   2009.7

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  235. 【Advanced Therapeutic Endoscopy】 EUS下穿刺術を応用した樹状細胞局注療法 Invited

    廣岡芳樹, 伊藤彰浩, 川嶋啓揮, 大野栄三郎, 石川卓哉, 松原浩, 伊藤裕也, 中村正直, 宮原良二, 大宮直木, 丹羽康正, 後藤秀実, 原和生, 金子亨, 後藤重則

    消化器内視鏡   Vol. 21 ( 6 ) page: 958-963   2009.6

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  236. A combination therapy of gemcitabine with immunotherapy for patients with inoperable locally advanced pancreatic cancer. Reviewed

    Hirooka Y, Itoh A, Kawashima H, Hara K, Nonogaki K, Kasugai T, Ohno E, Ishikawa T, Matsubara H, Ishigami M, Katano Y, Ohmiya N, Niwa Y, Yamamoto K, Kaneko T, Nieda M, Yokokawa K, Goto H.

    Pancreas   Vol. 38 ( 3 ) page: e69-74   2009.4

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  237. 膵石症に対する内視鏡的治療(膵管ステントは?) Invited

    川嶋啓揮, 廣岡芳樹, 伊藤彰浩, 春日井俊史, 大野栄三郎, 石川卓哉, 松原浩, 伊藤裕也, 中村正直, 宮原良二, 大宮直木, 丹羽康正, 後藤秀実

    肝・胆・膵   Vol. 58 ( 4 )   2009.4

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  238. *慢性膵炎に対する内視鏡的膵管ドレナージ術の治療成績 Invited Reviewed

    川嶋啓揮, 廣岡芳樹, 伊藤彰浩, 春日井俊史, 大野栄三郎, 石川卓哉, 松原浩, 丹羽康正, 後藤秀実

    膵臓   Vol. 24 ( 1 ) page: 41-46   2009.2

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  239. Feasibility of tissue elastography using transcutaneous ultrasonography for the diagnosis of pancreatic diseases. Reviewed

    Uchida H, Hirooka Y, Itoh A, Kawashima H, Hara K, Nonogaki K, Kasugai T, Ohno E, Ohmiya N, Niwa Y, Katano Y, Ishigami M, Goto H.

    Pancreas   Vol. 38 ( 1 ) page: 17-22   2009

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  240. 腹部超音波検査(US)、超音波内視鏡(EUS)、管腔内超音波検査(IDUS)による膵胆管合流異常の診断 Invited

    川嶋啓揮, 廣岡芳樹, 伊藤彰浩, 春日井俊史, 大野栄三郎, 石川卓哉, 松原浩, 宮原良二, 大宮直木, 丹羽康正, 後藤秀実

    胆と膵   Vol. 29 ( 10 ) page: 903-907   2008.10

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  241. *胆管癌表層進展範囲診断に対する経乳頭的胆管生検の有用性 Invited Reviewed

    川嶋啓揮, 廣岡芳樹, 伊藤彰浩, 春日井俊史, 大野栄三郎, 石川卓哉, 松原浩, 宮原良二, 大宮直木, 丹羽康正, 後藤秀実

    肝胆膵治療研究会誌   Vol. 6 ( 1 ) page: 16-21   2008.8

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  242. 広基性胆嚢腺腫の1例 Reviewed

    野々垣浩二, 廣岡芳樹, 伊藤彰浩, 川嶋啓揮, 原和生, 内田博起, 春日井俊史, 大野栄三郎, 大宮直木, 丹羽康正, 後藤秀実

    日本消化器病学会雑誌   Vol. 105 ( 1 ) page: 74-80   2008.1

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  243. 【胆道癌の早期診断と治療の選択】 胆嚢癌早期診断における胆嚢壁血流測定の有用性 Invited

    川嶋啓揮, 廣岡芳樹, 伊藤彰浩, 原和生, 内田博起, 野々垣浩二, 春日井俊史, 大野栄三郎, 大宮直木, 丹羽康正, 後藤秀実

    消化器科   Vol. 45 ( 3 ) page: 299-303   2007.9

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  244. FUTURE EXPECTATIONS OF NARROW BAND IMAGING SYSTEM FOR BILIOPANCREATIC DISEASEENDOSCOPIC APPROACH TO THE PANCREATOBILIARY TRACT USING NARROW BANDO IMAGING Invited Reviewed

    Akihiro Itoh,Yoshiki Hirooka Hiroki Kawashima,Yasumasa Nima Hidemi Goto

    Digestiv Endoscopy   Vol. 19 ( Suppl.1 ) page: 115-120   2007.7

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  245. 膵疾患の画像診断における最近のトピックス―膵臓疾患の超音波内視鏡診断― Invited Reviewed

    廣岡芳樹、伊藤彰浩、川嶋啓揮、原和生、内田博起、野々垣浩二、春日井俊史、大野栄三郎、大宮直木、丹羽康正、後藤秀実

    膵臓   Vol. 22   page: 95-109   2007.3

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  246. 膵の超音波内視鏡 Invited Reviewed

    廣岡芳樹、伊藤彰浩、川嶋啓揮、丹羽康正、後藤秀実

      Vol. 34 ( 3 ) page: 319-328   2007.3

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  247. 胆膵結石治療の進歩「内視鏡的膵石治療の適応」 Invited

    川嶋啓揮, 廣岡芳樹, 伊藤彰浩, 原和生, 内田博起, 野々垣浩二, 春日井俊史, 大野栄三郎, 大宮直木, 丹羽康正, 後藤秀実

    消化器科   Vol. 43 ( 6 ) page: 575-579   2007.2

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  248. 特集 膵・胆道周囲の腫瘤性病変-後腹膜を中心に 膵・胆道周囲の腫瘍性病変の画像「US,EUS,EUS-FNAによる後腹膜腫瘍の質的診断」 Invited

    川嶋啓揮、廣岡芳樹、伊藤彰浩、原和生、内田博起、野々垣浩二、春日井俊史、大野栄三郎、大宮直木、丹羽康正、後藤秀実

    消化器画像   Vol. 8 ( 6 ) page: 673-678   2006.11

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  249. 本邦の早期胆嚢癌の現状 Invited

    川嶋啓揮、廣岡芳樹、伊藤彰浩、原和生、内田博起、野々垣浩二、春日井俊史、大野栄三郎、大宮直木、丹羽康正、後藤秀実

    肝胆膵   Vol. 53 ( 2 ) page: 175-180   2006.8

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  250. Management Of Intraductal Papillary Mucinous Neoplasm Of The Pancreas Invited Reviewed

    Itoh, A., Hirooka, Y., Kawashima, H., Niwa, Y., Goto, H.

    Digestive Endoscopy   Vol. 18 ( Suppl.1 ) page: S64-S67   2006.7

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  251. 三次元体外式超音波による胆膵疾患の診断 Invited Reviewed

    橋本千樹, 廣岡芳樹, 伊藤彰浩, 川嶋啓揮, 原和生, 金森明, 内田博起, 後藤順, 丹羽康正, 吉岡健太郎, 後藤秀実

    超音波医学   Vol. 33 ( 4 ) page: 483-492   2006.7

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  252. *Progress of endoscopic ultrasonography and intraductal ultrasonography in the diagnosis of malignant biliary diseases Invited Reviewed

    Kawashima, H., Hirooka, Y., Itoh, A., Hara, K., Kanamori, A., Uchida, H., Goto, J., Nonogaki, K., Matsumoto, Y., Ohmiya, N., Niwa, Y., Goto H.

    Journal of Hepato-Biliary-Pancreatic Surgery   Vol. 13 ( 2 ) page: 69-74   2006.4

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  253. Usefulness of contrast-enhanced endoscopic ultrasonography in the differentiation between malignant and benign lymphadenopathy Reviewed

    Kanamori, A., Hirooka, Y., Itoh, A., Hashimoto, S., Kawashima, H., Hara, K., Uchida, H., Goto, J., Ohmiya, N., Niwa, Y., Goto, H.

    The American Journal of Gastroenterology   Vol. 101 ( 1 ) page: 45-51   2006.1

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  254. 膵石症に対する内視鏡治療の適応 Invited

    川嶋啓揮、廣岡芳樹、伊藤彰浩、原 和生、金森 明、内田博起、野々垣浩二、松本幸成、大宮直木、丹羽康正、後藤秀実

    胆と膵   Vol. 26 ( 11 ) page: 919-924   2005.11

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  255. 膵石症に対する最適治療としての内視鏡治療の適応 Invited

    川嶋啓揮、廣岡芳樹、伊藤彰浩、原 和生、金森 明、内田博起、後藤 順、野々垣浩二、松本幸成、大宮直木、丹羽康正、後藤秀実

    消化器科   Vol. 41 ( 5 ) page: 446-450   2005.11

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  256. Cholecystocolonic fistula preoperatively diagnosed by endoscopic ultrasound of the colon Reviewed

    Okada, N., Hirooka, Y., Itoh, A., Hashimoto, S., Ishikawa, H., Itoh, T., Kawashima, H., Goto H.

    Journal of Gastroen Hepatol   Vol. 20 ( 10 ) page: 1621-1624   2005.10

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  257. *Use of color Doppler ultrasonography in the diagnosis of anomalous connection in pancreatobiliary disease Reviewed

    Kawashima, H., Hirooka, Y., Itoh, A., Hashimoto, S., Itoh, T, Hara, K., Kanamori, A., Ohmiya, N., Niwa, Y., Goto, H.

    World J Gastroentero   Vol. 11 ( 7 ) page: 1018-1022   2005.2

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  258. Solitary fibrous tumor of the uterus producing high-molecular-weight insulin-like growth factor II and associated with hypoglycemia. Reviewed

    Wakami K, Takeyama H, Kawashima H, Matsuno T, Kamiya Y, Jin-No Y,Kimura G, Eimoto T

    Int J Gynecol Pathol   Vol. 24 ( 1 ) page: 79-84   2005.1

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  259. *Usefulness of Contrat-Enhanced Transabdominal Ultrasonography in the Diagnosis of Intraductal Papillary Mucinous Tumors of the Pancreas Reviewed

    Itoh, T., Hirooka, Y., Itoh, A., Hashimoto, S., Kawashima, H., Hara, K., Kanamori, A., Ohmiya, N., Niwa, Y., Goto H.

    Am J Gastroenterol   Vol. 100 ( 1 ) page: 144-152   2005.1

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  260. 十二指腸carcinoid tumorと術前診断された十二指腸gangliocytic paragangliomaの1例 Reviewed

    原 和生、廣岡芳樹、伊藤彰浩、橋本千樹、川嶋啓揮、金森 明、内田博起、後藤 順、大宮直木、丹羽康正、後藤秀実

    胆道   Vol. 18 ( 5 ) page: 614-619   2004.12

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  261. 膵疾患診断に対する造影超音波内視鏡(CE-EUS)および三次元超音波内視鏡(3D-EUS)の有用性 Invited Reviewed

    廣岡芳樹、伊藤彰浩、橋本千樹、川嶋啓揮、原 和生、金森 明、内田博起、後藤 順、石川重人、大宮直木、丹羽康正、後藤秀実

    膵臓   Vol. 19 ( 6 ) page: 598-607   2004.12

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▼display all

Presentations 70

  1. ERCPの基本と応用 Invited

    川嶋啓揮、廣岡芳樹、伊藤彰浩、後藤秀実

    第24回日本消化器内視鏡学会東海セミナー  2014.1 

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  2. 内視鏡的経鼻胆管ドレナージとFully covered metallic stentによる肝門部領域悪性胆道狭窄の術前ドレナージ

    川嶋啓揮、大野栄三郎、廣岡芳樹

    第105回日本消化器病学会総会  2019.5 

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    Presentation type:Symposium, workshop panel (public)  

  3. 内視鏡的乳頭切除術後の長期成績(適応拡大は可能か?

    川嶋啓揮、廣岡芳樹、後藤秀実

    第53回日本胆道学会学術集会  2017.9 

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  4. 肝門部領域胆管癌術前ドレナージにおける 6Fr 多孔式 ENBD カテーテルの有用性

    川嶋啓揮、廣岡芳樹、後藤秀実

    第53回日本胆道学会学術集会  2017.9 

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  5. 肝門部領域胆管癌術前減黄不良例の危険因子とその対処

    川嶋啓揮、廣岡芳樹、後藤秀実

    第101回日本消化器病学会総会  2015.4 

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  6. 安全な肝門部胆管癌術前の内視鏡的経鼻胆管トレナージを目指して

    川嶋啓揮、伊藤彰浩、後藤秀実

    第50回日本胆道学会学術集会  2014.9 

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  7. 内視鏡的十二指腸乳頭切除術の治療成績

    川嶋啓揮、廣岡芳樹、後藤秀実

    第50回日本胆道学会学術集会  2014.9 

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  8. 肝門部胆管癌の術前ドレナージ法

    川嶋啓揮、伊藤彰浩、後藤秀実

    第85回日本消化器内視鏡学会総会  2013.5 

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  9. ERCP・EUSの基本 Invited

    川嶋啓揮、廣岡芳樹、後藤秀実

    第28回日本消化器内視鏡学会東海セミナー  2018.1 

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  10. 教育講演                                 内視鏡的Papillectomyの現状と未来 Invited

    川嶋啓揮、廣岡芳樹、後藤秀実

    第10回日本消化管学会 教育集会  2016.9 

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  11. 胆膵悪性疾患の内視鏡診断と治療 Invited

    川嶋啓揮

    第26回日本消化器内視鏡学会東海セミナー  2016.1 

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  12. 日本胆道学会認定指導医養成講座5 乳頭部腫瘍に対する内視鏡治療 Invited

    川嶋啓揮

    第51回日本胆道学会学術集会  2015.9 

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    Presentation type:Oral presentation (invited, special)  

  13. Endoscopic Transpapillary Pancreatic Duct Drainage for Treatment and Prevention of Pancreatic Fistula after Pancreatic Surgery

    Kawashima H,  Hirooka Y, Itho A, Ohno E, Ishikawa T, Matsubara H, Itho Y, Nakamura Y, Hiramatsu T, Goto H

    2010.7 

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  14. 内視鏡的乳頭切除術の術前検査と術前・術中の準備 Invited

    川嶋啓揮

    第56回日本胆道学会学術集会  2020.10 

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  15. 術前精査でわかる内視鏡的乳頭切除術の偶発症危険因子と予後規定因子

    川嶋啓揮、大野栄三郎、藤城光弘

    第 99 回 日本消化器内視鏡学会総会  2020.9 

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  16. 苦痛まで考慮した肝門部領域胆管癌術前ドレナージ方法

    川嶋啓揮、大野栄三郎、石川卓哉、田中浩敬、飯田忠、西尾亮、鈴木博貴、植月康太、八鹿潤、山田健太、芳川昌功、宜保憲明、青木聡典、片岡邦夫、森 裕、 藤城光弘

    第55回日本胆道学会学術大会  2019.10 

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  17. 早期乳頭部癌に対する治療戦略 Invited

    川嶋啓揮

    Japan Digestive Disease Week 2019  2019.11 

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    Presentation type:Oral presentation (keynote)  

  18. 胆管内stent留置による肝門部領域胆管癌術前ドレナージの実際

    川嶋啓揮, 大野栄三郎, 藤城光弘

    第106回日本消化器病学会総会  2020.8 

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  19. 胆管癌診療と内視鏡的乳頭切除術(誌面発表のみ) Invited

    川嶋啓揮

    日本消化器病学会東海支部第132回例会  2020.6 

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  20. パネルディスカッション19-10胆管狭窄性病変の経乳頭的診断手技における偶発症の検討

    川嶋啓揮、伊藤彰浩、廣岡芳樹

    第78回 日本消化器内視鏡学会総会 

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    Event date: 2009.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  21. The utilities and complications of the endoscopic transpapillary forceps biopsy for diagnosis of the biliary strictures International conference

    Asian Pacific Digestive Week (APDW2009) Taipei, Taiwan 

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    Event date: 2009.10

    Language:English   Presentation type:Poster presentation  

  22. シンポジウム8-6膵管ステント留置術の偶発性と再治療を要する危険因子の検討

    川嶋啓揮、伊藤彰浩、廣岡芳樹

    第77回 日本消化器内視鏡学会総会 

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    Event date: 2009.5

    Language:Japanese  

  23. パネルディスカッション8-10当科におけるEUSにおける胆嚢癌壁深達度診断と経乳頭的胆管生検による胆嚢癌進展範囲診断の現状

    川嶋啓揮、廣岡芳樹、後藤秀実

    第95回 日本消化器病学会総会 

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    Event date: 2009.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  24. シンポジウム15(内視鏡・吸収)慢性膵炎に対する内視鏡的治療の有用性と問題点

    川嶋啓揮、伊藤彰浩、廣岡芳樹

    第76回 日本消化器内視鏡学会総会 

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    Event date: 2008.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  25. Relevant times of transpapillary forceps biopsy for accurate diagnosis of biliary strictures International conference

    16th United European Gastroenterology Week, Vienne, Austria 

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    Event date: 2008.10

    Language:English   Presentation type:Poster presentation  

    Hiroki Kawashima, Yoshiki Hirooka, Aihiro Itoh, Hiroki Uchida, Eizaburo Ohno, Toshihumi Kasugai, Ryoji Miyahara, Naoki Ohmiya, Yasumasa Niwa, Hidemi Goto

  26. ワークショップ(肝臓・消化器病・内視鏡)肝門部胆管病変診断に対する経乳頭的胆管生検の有用性

    川嶋啓揮、伊藤彰浩、廣岡芳樹

    第76回 日本消化器内視鏡学会総会 

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    Event date: 2008.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  27. パネルディスカッション 「良性胆道狭窄に対する治療戦略」良性胆道狭窄の診断と治療

    第44回日本胆道学会学術集会 

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    Event date: 2008.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

    川嶋啓揮、廣岡芳樹、伊藤彰浩、春日井俊史、大野栄三郎、石川卓哉、松原浩、宮原良二、大宮直木、丹羽康正、後藤秀実

  28. シンポジウム2-3 長期予後 合併症からみた慢性膵炎に対する内視鏡的膵管ドレナージ術

    第39回 日本膵臓学会大会 

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    Event date: 2008.7

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

    川嶋啓揮、廣岡芳樹、伊藤彰浩、原和生、春日井俊史、大野栄三郎、石川卓哉、大宮直木、丹羽康正、後藤秀実

  29. ワークショップ22 膵管ステントの適応と問題点

    川嶋啓揮、伊藤彰浩、廣岡芳樹

    第73回日本消化器内視鏡学会総会(DDW2007) 

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    Event date: 2007.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  30. Can we reduce complications and reinsertion of the pancreatic stent in the chronic pancreatitis cases? International conference

    Asian Pacific Digestive Week (APDW2007) 

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    Event date: 2007.10

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  31. シンポジウム4 経乳頭的膵管ドレナージの適応と選択

    川嶋啓揮、伊藤彰浩、廣岡芳樹

    第72回日本消化器内視鏡学会総会 

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    Event date: 2007.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  32. Risk Factors of Complications Both During Pancreatic Stent Placement and for Required Stent Reinsertion Cases in the Chronic Pancreatitis International conference

    DIGESTIVE DISEASE WEEK 2007 Washington 

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    Event date: 2007.5

    Language:English   Presentation type:Poster presentation  

  33. ワークショップ3「膵管stentingの功罪(ERCP後膵炎予防、慢性膵炎、膵仮性嚢胞および膵癌の治療)」膵管stentによる膵炎の予防と治療

    川嶋啓揮、伊藤彰浩、廣岡芳樹

    第71回日本消化器内視鏡学会総会 

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    Event date: 2006.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  34. パネルディスカッション5「胆膵結石の治療:up to date」内視鏡的膵石治療の適応

    川嶋啓揮、廣岡芳樹、伊藤彰浩

    第92回日本消化器病学会総会 

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    Event date: 2006.4

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  35. ワークショップ15「慢性膵炎の合併症と長期予後」慢性膵炎の合併症の危険因子に関する検討

    川嶋啓揮、伊藤彰浩、廣岡芳樹

    第70回日本消化器内視鏡学会総会(DDW2005) 

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    Event date: 2005.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  36. パネルディスカッション9「内視鏡による膵疾患へのアプローチ-その適応と工夫-」慢性膵炎、膵石症の内視鏡的診断と少量膵液による遺伝子解析

    川嶋啓揮、伊藤彰浩、廣岡芳樹

    第69回日本消化器内視鏡学会総会 

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    Event date: 2005.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  37. Predictors of Prolonged Treatment Duration: Laser and/or Extracorporeal Shock Wave Lithotripsy of the Pancreatic Stones International conference

    Digestive Disease Week 2005 Chicago(ASGE) 

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    Event date: 2005.5

    Language:English   Presentation type:Poster presentation  

  38. ビデオシンポジウム7「胆膵管狭窄に対する内視鏡手技とその後の管理」良性膵管狭窄に対する膵管ステント留置の有用性と合併症、再発危険因子の検討

    川嶋啓揮、伊藤彰浩、廣岡芳樹

    第69回日本消化器内視鏡学会総会 

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    Event date: 2005.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  39. パネルディスカッション「膵石症に対する最適治療としての内視鏡的治療の適応」

    川嶋啓揮、伊藤彰浩、後藤秀実

    第91回日本消化器病学会総会 

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    Event date: 2005

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  40. ワークショップ「EUS下穿刺の現況」膵、後腹膜腫瘍の治療方針決定に対するEUS下穿刺生検の有用性

    川嶋啓揮、伊藤彰浩、廣岡芳樹

    第46回日本消化器病学会大会 

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    Event date: 2004.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  41. ワークショップ「膵管ステントと内視鏡的経鼻膵管ドレナージ」膵管ステントによる膵炎の発症予防と治療

    川嶋啓揮、伊藤彰浩、廣岡芳樹

    第67回日本消化器内視鏡学会総会 

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    Event date: 2004.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  42. Usefulness of color doppler ultrasonography in the diagnosis of anomalous pancreaticobiliary ductal union International conference

    Digestive Disease Week 2004 New Orleans AGA 

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    Event date: 2004.5

    Language:English   Presentation type:Poster presentation  

  43. Usefulness of contrast-enhanced extracorporeal ultrasonography in the diagnosis of gallbladder disease International conference

    4th International Symposium on Ultrasound 

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    Event date: 2002.12

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  44. Debate Session What is the Optimal Preoperative Biliary Drainage for HBP Malignancy:ENBD vs ERBD DS-6-1 Preoperative ENBD for perihilar cholanglocarcinoma patients Invited International conference

    Kawashima H

    6th A-PHPBA 29th JSHBPS  2017.6 

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    Language:English   Presentation type:Oral presentation (keynote)  

    Country:Japan  

  45. Endoscopic ampullectomy: Nagoya experience Invited

    Kawashima H

    NUH-NCI Endoscopic Joint Meeting  2016.1 

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    Presentation type:Oral presentation (keynote)  

    Country:Thailand  

  46. Current situation of ERCP in Japan Live demonstrator Invited

    Kawashima H

    第七届東方胆膵ERCP学会  2015.9 

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    Language:English   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Country:China  

  47. Therapeutic endoscopic retrograde cholangiography using balloon-assisted enteroscopy (BAE-ERC) in Nagoya University Hospital Live demonstrator Invited International conference

    Kawashima H

    The 7th National ERCP symposium  2014.8 

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    Language:English   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Country:China  

  48. 内視鏡的十二指腸乳頭切除術早期偶発症の現状と対策

    川嶋啓揮、廣岡芳樹、後藤秀実

    第23回日本消化器関連学会週間  2015.10 

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    Presentation type:Symposium, workshop panel (public)  

  49. 胆道癌における閉塞性黄疸例の術前ドレナージ法の検討

    川嶋啓揮、廣岡芳樹、後藤秀実

    第86回日本消化器内視鏡学会総会  2013.10 

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    Presentation type:Symposium, workshop panel (public)  

  50. 広範囲肝切除を必要とする悪性肝門部胆道狭窄に対する内視鏡的経鼻胆道ドレナージと経乳頭的胆管生検

    川嶋啓揮、伊藤彰浩、廣岡芳樹

    第81回日本消化器内視鏡学会総会  2011.8 

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    Presentation type:Symposium, workshop panel (public)  

  51. 経乳頭的胆管生検による胆管狭窄病変診断の実際

    川嶋啓揮、伊藤彰浩、廣岡芳樹

    第79回日本消化器内視鏡学会総会  2010.5 

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    Presentation type:Symposium, workshop panel (public)  

  52. 内視鏡的十二指腸乳頭切除術における病理断端評価と長期予後の関連

    川嶋啓揮、廣岡芳樹、後藤秀実

    第95回日本消化器内視鏡学会総会  2018.5 

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    Presentation type:Symposium, workshop panel (public)  

  53. 未処置乳頭肝門部領域胆管狭窄症例に対する経乳頭的胆管生検と経鼻胆管ドレナージの現状

    川嶋啓揮、廣岡芳樹、後藤秀実

    第104回日本消化器病学会総会  2018.4 

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    Presentation type:Symposium, workshop panel (public)  

  54. 十二指腸乳頭部癌に対する内視鏡的乳頭切除術の治療成績

    川嶋啓揮、廣岡芳樹、後藤秀実

    第59回日本消化器病学会大会  2017.10 

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    Presentation type:Symposium, workshop panel (public)  

  55. 内視鏡的十二指腸乳頭切除術の治療成績と長期予後

    川嶋啓揮、廣岡芳樹、後藤秀実

    第93回日本消化器内視鏡学会総会  2017.5 

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    Presentation type:Symposium, workshop panel (public)  

  56. 内視鏡的手技による肝門部胆道癌術前マネージメント

    川嶋啓揮、廣岡芳樹、後藤秀実

    第87回日本消化器内視鏡学会総会  2014.5 

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    Presentation type:Symposium, workshop panel (public)  

  57. 教育講演 術者の気持ちがわかるERCPの基本 Invited

    川嶋啓揮

    日本消化器内視鏡学会東海支部技師会  2018.11 

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    Presentation type:Public lecture, seminar, tutorial, course, or other speech  

  58. ERCPとその関連手技のガイドライン Invited

    川嶋啓揮

    第18回日本消化器内視鏡学会東海支部ガイドライン研修会  2018.7 

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    Presentation type:Public lecture, seminar, tutorial, course, or other speech  

  59. ERCP関連手技のガイドライン Invited

    川嶋啓揮、廣岡芳樹、後藤秀実

    第17回日本消化器内視鏡学会東海支部ガイドライン研修会  2017.7 

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    Presentation type:Public lecture, seminar, tutorial, course, or other speech  

  60. 「症例検討〜あなたならどうする〜」 第2部 症例提示者 Invited

    川嶋啓揮

    第46回日本膵臓学会大会  2015.6 

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    Presentation type:Oral presentation (invited, special)  

  61. 胆道・膵臓疾患の内視鏡による診断と治療 Invited

    川嶋啓揮

    第81回日本消化器病学会東海支部市民公開講座  2011.12 

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    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

  62. あなたの超音波検査の疑問に専門家が答える Invited

    川嶋啓揮

    日本消化器集団検診学会 東海北陸支部 超音波部会第3回超音波セミナー  2005.9 

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    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

  63. 内視鏡的十二指腸乳頭切除術の治療成績と長期予後

    川嶋啓揮、廣岡芳樹、後藤秀実

    第93回日本消化器内視鏡学会総会  2017.5 

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    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

  64. Preoperative endoscopic nasobiliary drainage (ENBD) in perihilar cholangiocarcinoma patients: A single-center retrospective cohort study of 439 patients"

    Kawashima H, Hirooka Y, Ohno E, Kuwahara T, Yamamura T, Funasaka K, Nakamura M, Miyahara R, Watanabe O, Goto H.

    Asia Pacific Digestive Week (APDW)2016  2016.11 

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    Language:English   Presentation type:Poster presentation  

  65. 悪性胆道狭窄に対するドレナージ戦略のトレンドを追う-Metallic Stentingを中心とした現状と将来展望- Invited

    川嶋啓揮

    Japan Digestive Disease Week 2016  2016.11 

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    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

  66. Live demonstrator Invited International conference

    Kawashima H

    TAGE-Rajavity Endoscopy Symposium  2017.11 

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    Language:English   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Country:Thailand  

  67. 新しい胆膵治療デバイスの使用経験 ~造影カテーテルとガイドワイヤー~ Invited

    川嶋啓揮

    第 99 回 日本消化器内視鏡学会総会  2020.9 

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    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

  68. MWS9難渋する胆道ドレナージの工夫

    川嶋啓揮

    第56回日本胆道学会学術集会  2020.10 

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    Language:Japanese   Presentation type:Oral presentation (general)  

  69. 肝門部領域胆管癌の術前評価とドレナージ~安全で苦痛の少ない手技を目指して~ Invited

    川嶋啓揮

    第55回日本胆道学会学術大会  2019.10 

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    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

  70. ERCP・DBERCPによる胆道疾患の診断と治療~やればやるほど奥深い胆道の世界~ Invited

    川嶋啓揮

    第55回日本胆道学会学術大会  2019.10 

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    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

▼display all

KAKENHI (Grants-in-Aid for Scientific Research) 7

  1. Development of new diagnostic method for duodenal ampullary carcinoma amenable to local excision

    Grant number:18K08614  2018.4 - 2021.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\4420000 ( Direct Cost: \3400000 、 Indirect Cost:\1020000 )

  2. 胆膵疾患の十二指腸主乳頭擦過採取による表在細菌叢プロファイル作成と臨床応用の探索

    Grant number:21K19897  2021.7 - 2024.3

    科学研究費助成事業  挑戦的研究(萌芽)

    川嶋 啓揮

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\3640000 ( Direct Cost: \2800000 、 Indirect Cost:\840000 )

  3. 免疫チェックポイント阻害剤抵抗性を改善する革新的膵癌治療法の開発

    Grant number:21K07941  2021.4 - 2024.3

    科学研究費助成事業  基盤研究(C)

    飯田 忠, 大野 栄三郎, 石川 卓哉, 川嶋 啓揮, 藤城 光弘

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    Authorship:Coinvestigator(s)  Grant type:Competitive

    膵がんに代表される難治がんは免疫チェックポイント阻害剤(以下ICI)に対して抵抗性であり、その原因としてCAFが重要な役割を担っている。近年の研究によりCAFを促進性から抑制性にリプログラム(CAF初期化)させることで抵抗性が改善される可能性が示唆されているがその有効性に関しては明らかとなっていない。我々はMeflinを指標とすることでCAF初期化薬の候補薬を既に同定しており、本研究ではこれらの薬剤とICIとの併用効果を検証し、間質をターゲットとした革新的新規治療法の確立を目指す。

  4. 炎症性腸疾患における新規粘膜関連細菌叢検出法を用いた腸粘膜炎症プロファイルの作成

    Grant number:20K07801  2020.4 - 2023.3

    中村 正直

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    Authorship:Coinvestigator(s) 

    炎症性腸疾患の腸表面の粘膜関連細菌叢から粘膜固有層までの免疫増幅経路は同時に同部位で評価すべき事象である。同じ部位の内視鏡生検検体を用いて、A)粘膜関連細菌叢の最適検出法を見出したうえで採取、細菌16SrRNA次世代シークエンス解析を行う。B)生検組織のフローサイトメトリーによる免疫担当細胞とT細胞の分布解析、細胞内炎症性サイトカインの定量を行い、免疫応答をカテゴリー化する。C)粘膜内蛋白質量解析により、炎症反応のKeyとなる分子の量と種類につき網羅的に解析する。A)B)C)から得た結果を疾患活動性とリンクさせ、腸粘膜炎症プロファイルを作成する。

  5. Clinical Application of Artificial Intelligence to Improve Diagnostic Performance of Endoscopic Ultrasound for Pancreatic Diseases

    Grant number:20K12689  2020.4 - 2023.3

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    Authorship:Coinvestigator(s) 

  6. 超音波内視鏡下エラストグラフィによる組織硬度測定による膵癌の臨床病理学的病態解析

    Grant number:18K12054  2018.4 - 2021.3

    科学研究費助成事業  基盤研究(C)

    大野 栄三郎, 川嶋 啓揮, 廣岡 芳樹, 宮原 良二, 中村 正直, 石川 卓哉

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    Authorship:Coinvestigator(s)  Grant type:Competitive

    膵癌は豊富な線維性間質(がん関連線維芽細胞:cancer-associated fibroblast:CAF)を有し、「硬い」腫瘍と認識され、一方で癌細胞は硬い組織環境下において更に悪性度を増すとの報告も認め、膵癌およびその周囲組織の硬度と膵癌細胞の悪性度及び進行度に密接に関連している可能性がある。膵癌組織においてCAFは単なるbystanderではなく膵癌の進展など病態に強く関わっていることも報告されている。我々は臨床的に膵癌の硬度を測定し(超音波内視鏡下エラストグラフィ及び組織に対する原子間力顕微鏡(AFM))、硬度と膵癌の病理像(癌促進性、癌抑制性CAFの比率、分布)と臨床像(予後、化学療法の奏功率)との関連性を明らかにすることを目的としている。
    1)EUS-SWE(EUS-guided shear wave elastography)による膵癌を含む膵病変組織硬度測定
    超音波エラストグラフィは非侵襲的に組織弾性を測定し画像化、数値化する技術である。本年はEUS-SWEの膵癌をはじめとする膵病変の組織硬度測定精度の検証を行うため、もう一つの超音波エラストグラフィシステムであるStrain elastography法と対比して、硬度測定を行い(学会報告、論文報告JMU2019)、膵癌組織硬度測定における超音波エラストグラフィの使用方法に関する最適な測定条件を見いだす。
    2)膵癌、膵腫瘍患者の進行度と治療効果と組織硬度との関連性の検討
    EUS-SWE、超音波エラストグラフィにて得られた組織硬度は膵癌や自己免疫性膵炎(ステロイド治療前)にて他膵腫瘤性病変や正常膵に比して高硬度を示した。切除病理標本の免疫組織染色(AZAN,αSMA, CD31)による検討では、高硬度を示す膵癌においては膵癌組織中の線維芽細胞の比率が高い傾向を認めた。(未発表)
    EUS-SWを用いた膵癌、膵腫瘍測定における精度評価、問題点を抽出し、学会報告を行った。また現在論文投稿中である。硬度測定においてはStrain elastography法をヒストグラム解析にて半定量化する結果を用いることで診断精度の向上を認めた。
    現在、実際の膵癌の組織硬度測定結果と病理組織の免疫組織学的検討との対比を行うと同時に、組織硬度に関連するタンパク、CAFの発現を病理組織FFPE標本を用い検討する準備を行っている。臨床面においては膵癌組織硬度の差異をEUS-FNAによる針生検の病理組織所見との対比を行う前向き研究、膵癌化学療法前後における組織硬度変化の前向き研究を現在on goingにて進行中である。
    1)膵癌切除症例の病理組織所見と術前画像所見の対比:膵癌切除病理標本の間質組織の組成、成分解析を行うための免疫染色を行う。昨年度施行した免疫染色に加え、ミオシン軽鎖染色、Yap染色を追加する予定。さらに、線維芽細胞の組織硬度に関連すると考えられるlysyl oxidase(Lox)発現量を免疫染色にて評価を行う。(継続課題)
    2)膵癌組織硬度と発現遺伝子異常の相関の検討:膵癌組織を間質のCAFの発現、硬度により分類し、硬度の異なる膵癌組織における遺伝子異常の発現プロファイルを探索するため、EUS-FNAにて採取された膵癌検体もしくは切除例の病理組織標本よりlaser microdissection法にて癌組織を切り出し、癌組織よりDNAを抽出し、膵癌に代表的に認められる遺伝子変異をマイクロアレイにて解析し、硬度の異なる膵癌の遺伝子プロファイルの差異を検討する。(継続課題)
    3)物理的な膵癌をはじめとした臓器、組織の硬度測定法の開発を目指す。
    臓器の組織組成、物理学的な生体組織の特性を評価し、既存の診断機器、治療機器、デバイスの機能的特性を新たな研究領域として体系化する。具体的には細胞硬度、細胞集塊硬度、組織硬度、臓器硬度にスケール分類した場合、各スケールに併せた適切な硬度測定方法を確立する。当面、臨床的に最優先の課題としては生検にて採取された細胞集塊の硬度測定の定量化と実際の疾患、病態、既存の硬度測定(エラストデータ)との相関を示すベースとなるデータの集積を行う。
    1)2)に関しては既存の膵癌組織を用いた遺伝子プロファイル、タンパク発現解析を目的としたゲノム解析研究専門審査委員会の承認を得て研究を開始している。

  7. Evaluation of biomarkers related to intestinal epithelial disorder using endoscopic biopsy specimen

    Grant number:16K09406  2016.4 - 2020.3

    Nakamura Masanao

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    Authorship:Coinvestigator(s) 

    Intestinal biopsy specimen in endoscopy revealed the distribution of mRNA expression of biological marker in human small intestinal mucosa, and showed that nutrient absorption structure could be maintained in intestinal mucosa of patients with small bowel disease. Factors related to intestinal epithelial damage in acute enteritis model mice were examined, and we considered the potential of regenerative medicine in the treatment. Focusing on some components of stem cells, we showed their anti-inflammatory and healing effects for acute colitis. Considering the relationship between the intestinal epithelium and the mucosa-associated bacterial flora, the sample of intestinal mucosa was collected with a brush forceps during endoscopy and we showed a strong relationship between the mucosa-associated bacterial flora and colitis.

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Teaching Experience (On-campus) 6

  1. 胆道・膵疾患

    2020

  2. 胆道・膵疾患

    2019

  3. 膵疾患

    2018

  4. 膵疾患

    2017

  5. 膵疾患

    2016

  6. 膵疾患

    2015

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