Updated on 2025/03/07

写真a

 
INDEN, Yasuya
 
Organization
Graduate School of Medicine Program in Integrated Medicine Internal Medicine Associate professor
Graduate School
Graduate School of Medicine
Undergraduate School
School of Medicine Department of Medicine
Title
Associate professor
Contact information
メールアドレス

Degree 1

  1. 博士(医学)(登録番号第2925号) ( 2001.9   名古屋大学 ) 

Research Interests 3

  1. 心不全

  2. 不整脈

  3. 循環器

Research Areas 1

  1. Others / Others  / Cardiology

Education 1

  1. Nagoya University   Faculty of Medicine

    - 1988.3

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    Country: Japan

Professional Memberships 4

  1. Japanese Heart Failure Society

  2. Japanese Heart Rhythm Society

  3. The Japanese Circulation Society

  4. 日本内科学会

Awards 1

  1. 第11回 医科学応用研究財団助成による日本心電学会論文賞

    2011.9   心電学会  

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    Country:Japan

 

Papers 159

  1. Global myocardial work index predicts response to biventricular pacing in patients with non-left bundle branch block

    Kondo, S; Inden, Y; Yanagisawa, S; Miyamae, K; Miyazawa, H; Goto, T; Tachi, M; Iwawaki, T; Yamauchi, R; Hiramatsu, K; Shimojo, M; Tsuji, Y; Murohara, T

    ESC HEART FAILURE     2025.2

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  2. Peak frequency drop: a novel intraprocedural parameter predicting acute conduction gaps post-pulmonary vein isolation

    Mizutani, Y; Matsumoto, Y; Nishio, K; Sakai, H; Fujiwara, G; Nonokawa, D; Makino, Y; Suzuki, H; Ichimiya, H; Uchida, Y; Watanabe, J; Kanashiro, M; Yanagisawa, S; Inden, Y; Murohara, T

    JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY     2025.2

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  3. Decreased left ventricular systolic function during the late phase after response to cardiac resynchronization therapy.

    Iwawaki T, Inden Y, Yanagisawa S, Miyamae K, Miyazawa H, Goto T, Kondo S, Tachi M, Shimojo M, Tsuji Y, Murohara T

    Heart rhythm     2025.2

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    Language:English  

    DOI: 10.1016/j.hrthm.2025.02.002

    PubMed

  4. Editorial to "Novel mapping techniques for ablation of non-pulmonary vein foci using complex signal identification"

    Mizutani, Y; Yanagisawa, S; Inden, Y

    JOURNAL OF ARRHYTHMIA   Vol. 41 ( 1 ) page: e70006   2025.2

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  5. Feasibility of left bundle branch area pacing with left axillary pacemaker implantation in a young female patient with heart failure

    Kato, H; Narita, Y; Yanagisawa, S; Inden, Y; Murohara, T

    JOURNAL OF ARRHYTHMIA   Vol. 41 ( 1 ) page: e70022   2025.2

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  6. Editorial to "Pre-procedural imaging guiding ventricular tachycardia ablation in structural heart disease".

    Mizutani Y, Yanagisawa S, Inden Y

    Journal of arrhythmia   Vol. 41 ( 1 ) page: e13211   2025.2

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    DOI: 10.1002/joa3.13211

    PubMed

  7. Left internal thoracic artery injury in percutaneous epicardial access for catheter ablation: Prevention and management.

    Morishima I, Morita Y, Kanzaki Y, Miyazawa H, Shimojo K, Inden Y

    HeartRhythm case reports   Vol. 11 ( 2 ) page: 159 - 163   2025.2

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    DOI: 10.1016/j.hrcr.2024.11.004

    PubMed

  8. A simple technique for manipulating a pentaspline pulsed field ablation catheter to select right inferior pulmonary vein using vertebral body alignment

    Mizutani, Y; Nonokawa, D; Kanashiro, M; Yanagisawa, S; Inden, Y; Murohara, T

    JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY     2025.1

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  9. "Performance of the novel ANTWERP score in predicting heart function improvement after atrial fibrillation ablation in Asian patients with heart failure"

    Yanagisawa, S; Inden, Y; Murohara, T

    JOURNAL OF ARRHYTHMIA   Vol. 40 ( 6 ) page: 1370 - 1371   2024.12

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  10. Editorial to "investigating the role of electroanatomical mapping in single-shot pulsed field catheter ablation"

    Mizutani, Y; Yanagisawa, S; Inden, Y

    JOURNAL OF ARRHYTHMIA   Vol. 40 ( 6 ) page: 1379 - 1380   2024.12

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  11. Do not stop effective atrial-based antitachycardia pacing: Insights into episode duration and success rate for termination.

    Yanagisawa S, Sato Y, Shimizu A, Narita Y, Inden Y, Murohara T

    HeartRhythm case reports   Vol. 10 ( 12 ) page: 867 - 871   2024.12

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    DOI: 10.1016/j.hrcr.2024.08.016

    PubMed

  12. Differentiation between epicardial and endocardial conduction gaps for left atrial posterior wall isolation using peak frequency annotation algorithm.

    Suga K, Kato H, Murakami H, Yanagisawa S, Inden Y, Murohara T

    HeartRhythm case reports   Vol. 10 ( 12 ) page: 912 - 916   2024.12

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    DOI: 10.1016/j.hrcr.2024.08.028

    PubMed

  13. An abrupt loss of capture during permanent His-bundle pacing: Assessment of mechanism underlying late capture threshold rise

    Kato, H; Yanagisawa, S; Ota, R; Inden, Y; Murohara, T

    JOURNAL OF ARRHYTHMIA   Vol. 40 ( 6 ) page: 1525 - 1528   2024.12

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  14. Identification of regions maintaining atrial fibrillation through cycle length and cycle length gradient mapping

    Shimojo, M; Inden, Y; Yanagisawa, S; Yamauchi, R; Hiramatsu, K; Iwawaki, T; Tachi, M; Kondo, S; Goto, T; Tsuji, Y; Murohara, T

    JOURNAL OF ARRHYTHMIA   Vol. 40 ( 6 ) page: 1389 - 1399   2024.12

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  15. Synthesized V7 QRS Amplitude and Oversensing Episodes in Patients With Subcutaneous Implantable Cardioverter-Defibrillators

    Okajima, T; Ishikawa, S; Yanagisawa, S; Okamoto, T; Uemura, Y; Takemoto, K; Inden, Y; Murohara, T; Watarai, M

    PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY   Vol. 47 ( 12 ) page: 1565 - 1573   2024.12

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  16. Reply to the Editor -Additional value of venous flow pattern for ultrasound-guided venous closure with suture-mediated vascular closure device.

    Tachi M, Tanaka A, Teraoka T, Furuta T, Matsushita E, Hayashi K, Shimojo M, Yanagisawa S, Inden Y, Murohara T

    Heart rhythm     2024.11

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    DOI: 10.1016/j.hrthm.2024.11.006

    PubMed

  17. Optimal ablation settings of TactiFlex SE laser-cut irrigated-tip catheter: comparison with ThermoCool SmartTouch SurroundFlow porous irrigated-tip catheter

    Suga, K; Kato, H; Akita, S; Sakurai, T; Ota, R; Okada, T; Murakami, H; Kada, K; Tsuboi, N; Yanagisawa, S; Inden, Y; Murohara, T

    JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY   Vol. 67 ( 8 ) page: 1755 - 1769   2024.11

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  18. Early Cryoablation After First Diagnosis of Atrial Fibrillation Reduces Arrhythmia Recurrence in Heart Failure Patients.

    Ando M, Yanagisawa S, Suzuki H, Yoshida Y, Kanzaki Y, Morishima I, Ishikawa S, Kamikubo Y, Okumura S, Kato H, Mizutani Y, Murase Y, Nakasuka K, Warita S, Sekimoto S, Takemoto Y, Takasugi N, Ohguchi S, Senga M, Yokoi K, Watanabe R, Ogura Y, Shibata R, Inden Y, Murohara T

    JACC. Asia   Vol. 4 ( 11 ) page: 857 - 871   2024.11

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    DOI: 10.1016/j.jacasi.2024.08.005

    PubMed

  19. Feasibility and efficacy of real-time ultrasound-guided venous closure with suture-mediated vascular closure device

    Tachi, M; Tanaka, A; Teraoka, T; Furuta, T; Matsushita, E; Hayashi, K; Shimojo, M; Yanagisawa, S; Inden, Y; Murohara, T

    HEART RHYTHM   Vol. 21 ( 10 ) page: 2028 - 2036   2024.10

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  20. Reversible complete left bundle branch block and a wide QRS complex following administration of sodium-glucose cotransporter-2 inhibitor and volume reduction in a patient with systolic heart failure: a case report

    Takenaka, M; Yanagisawa, S; Yoshida, Y; Inden, Y; Murohara, T

    EUROPEAN HEART JOURNAL-CASE REPORTS   Vol. 8 ( 9 ) page: ytae512   2024.9

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  21. A Novel Liver Fibrosis Marker FIB-5 Index Predicted Response to Cardiac Resynchronization Therapy and Prognostic Outcomes in Patients With Heart Failure

    Iwawaki, T; Inden, Y; Yanagisawa, S; Goto, T; Kondo, S; Tachi, M; Hiramatsu, K; Yamauchi, R; Shimojo, M; Tsuji, Y; Murohara, T

    ANNALS OF NONINVASIVE ELECTROCARDIOLOGY   Vol. 29 ( 5 ) page: e70004   2024.9

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  22. The benefits of ablation using TactiFlex compared with TactiCath in an ex vivo model: a face-to-face experimental comparison study

    Odake, Y; Tokuyama, T; Aonuma, K; Kuroki, K; Inden, Y; Furutani, M; Okubo, Y; Okamura, S; Miyauchi, S; Miyamoto, S; Oguri, N; Uotani, Y; Sakai, T; Nakano, Y

    JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY     2024.8

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  23. Long-Term Outcomes in Patients With Relatively High His-Bundle Capture Threshold After Permanent His-Bundle Pacing - A Multicenter Clinical Study.

    Watanabe R, Kato H, Yanagisawa S, Sakurai T, Ota R, Murakami H, Kada K, Tsuboi N, Inden Y, Shibata R, Murohara T

    Circulation reports   Vol. 6 ( 8 ) page: 294 - 302   2024.8

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    DOI: 10.1253/circrep.CR-24-0035

    PubMed

  24. Long-Term Outcomes in Patients With Relatively High His-Bundle Capture Threshold After Permanent His-Bundle Pacing ― A Multicenter Clinical Study ―

    Watanabe, R; Kato, H; Yanagisawa, S; Sakurai, T; Ota, R; Murakami, H; Kada, K; Tsuboi, N; Inden, Y; Shibata, R; Murohara, T

    CIRCULATION REPORTS   Vol. 6 ( 8 ) page: 294 - 302   2024.8

  25. Long-Term Outcomes in Patients With Relatively High His-Bundle Capture Threshold After Permanent His-Bundle Pacing ― A Multicenter Clinical Study ―

    Watanabe, R; Kato, H; Yanagisawa, S; Sakurai, T; Ota, R; Murakami, H; Kada, K; Tsuboi, N; Inden, Y; Shibata, R; Murohara, T

    CIRCULATION REPORTS   Vol. 6 ( 8 ) page: 294 - 302   2024.8

  26. Elevated liver fibrosis-4 index predicts recurrence after catheter ablation for atrial fibrillation in patients with heart failure

    Iwawaki, T; Morishima, I; Kanzaki, Y; Morita, Y; Watanabe, N; Yoshioka, N; Shibata, N; Miyazawa, H; Shimojo, K; Yanagisawa, S; Inden, Y; Murohara, T

    JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY   Vol. 67 ( 5 ) page: 1093 - 1108   2024.8

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  27. Evaluation of microembolic signals on carotid ultrasound during pulmonary vein isolation with high-power short-duration and cryoballoon ablations: When and where do bubble and solid emboli arise?

    Mizutani, Y; Yanagisawa, S; Ichikawa, M; Nishio, K; Sakai, H; Nonokawa, D; Makino, Y; Suzuki, H; Ichimiya, H; Uchida, Y; Watanabe, J; Kanashiro, M; Inden, Y; Murohara, T

    JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY   Vol. 35 ( 8 ) page: 1589 - 1600   2024.8

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  28. Editorial to "Notched P-wave on digital electrocardiogram predicts the recurrence of atrial fibrillation in patients who have undergone catheter ablation"

    Yanagisawa, S; Inden, Y; Murohara, T

    JOURNAL OF ARRHYTHMIA   Vol. 40 ( 4 ) page: 790 - 791   2024.8

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  29. Refractory atrial tachycardia after transcatheter closure of an atrial septal defect, successfully treated by catheter ablation with transseptal approach via the side of the device.

    Hiramatsu K, Tanaka A, Furusawa K, Inden Y, Murohara T

    Journal of cardiology cases   Vol. 29 ( 6 ) page: 258 - 260   2024.6

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    DOI: 10.1016/j.jccase.2024.02.007

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  30. Mid-term outcomes of delivery catheter-based and stylet-based right ventricular septal pacing: Follow-up results from a multicenter, prospective, randomized study

    Tsurumi, N; Naruse, Y; Kurebayashi, N; Morikawa, S; Sano, M; Shiozawa, T; Takano, S; Ogano, M; Kimura, K; Miyajima, K; Sugiura, R; Henmi, R; Muto, M; Hosoya, N; Hasebe, H; Mizukami, A; Iguchi, K; Atsumi, A; Odagiri, K; Yanagisawa, S; Inden, Y; Murohara, T; Maekawa, Y

    JOURNAL OF ARRHYTHMIA   Vol. 40 ( 3 ) page: 605 - 613   2024.6

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  31. Coagulation Profile After Catheter Ablation for Ventricular Tachycardia in Antiplatelet and Anticoagulant Regimens

    Yanagisawa, S; Inden, Y; Iwawaki, T; Tachi, M; Hiramatsu, K; Yamauchi, R; Shimojo, M; Tsuji, Y; Shibata, R; Murohara, T

    JACC-CLINICAL ELECTROPHYSIOLOGY   Vol. 10 ( 5 ) page: 976 - 978   2024.5

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  32. Comparison of novel intrinsic versus conventional antitachycardia pacing for ventricular tachycardia among implantable cardioverter-defibrillator recipients

    Yanagisawa, S; Inden, Y; Sato, Y; Watanabe, R; Goto, T; Kondo, S; Tachi, M; Iwawaki, T; Yamauchi, R; Hiramatsu, K; Shimojo, M; Tsuji, Y; Shibata, R; Murohara, T

    JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY   Vol. 35 ( 4 ) page: 821 - 831   2024.4

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  33. Mechanisms of torsades de pointes: an update

    Tsuji, Y; Yamazaki, M; Shimojo, M; Yanagisawa, S; Inden, Y; Murohara, T

    FRONTIERS IN CARDIOVASCULAR MEDICINE   Vol. 11   page: 1363848   2024.3

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  34. Distributions and number of drivers on real-time phase mapping associated with successful atrial fibrillation termination during catheter ablation for non-paroxysmal atrial fibrillation

    Riku, S; Inden, Y; Yanagisawa, S; Fujii, A; Tomomatsu, T; Nakagomi, T; Shimojo, M; Okajima, T; Furui, K; Suga, K; Suzuki, S; Shibata, R; Murohara, T

    JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY   Vol. 67 ( 2 ) page: 303 - 317   2024.3

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  35. REPLY: Methodological and Mechanistic Considerations in Local Repolarization Mapping

    Yanagisawa, S; Inden, Y; Tsuji, Y; Shibata, R; Murohara, T

    JACC-CLINICAL ELECTROPHYSIOLOGY   Vol. 10 ( 2 ) page: 378 - 378   2024.2

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  36. Editorial to "pseudo-slow-fast atrioventricular nodal reentrant tachycardia: Is the fast pathway a criminal or innocent bystander?".

    Mizutani Y, Yanagisawa S, Inden Y

    Journal of arrhythmia   Vol. 40 ( 1 ) page: 146 - 147   2024.2

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    DOI: 10.1002/joa3.12978

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  37. Usefulness of omnipolar technology near field for accessory pathway ablation through the coronary sinus.

    Mizutani Y, Yanagisawa S, Matsumoto Y, Kanashiro M, Inden Y, Murohara T

    HeartRhythm case reports   Vol. 10 ( 1 ) page: 92 - 95   2024.1

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    DOI: 10.1016/j.hrcr.2023.10.030

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  38. Clinical outcomes and predictors of delayed echocardiographic response to cardiac resynchronization therapy

    Tsurumi, N; Inden, Y; Yanagisawa, S; Hiramatsu, K; Yamauchi, R; Watanabe, R; Suzuki, N; Shimojo, M; Suga, K; Tsuji, Y; Murohara, T

    JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY   Vol. 35 ( 1 ) page: 97 - 110   2024.1

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  39. Triggers of Ventricular Fibrillation in Patients With Inferolateral J-Wave Syndrome

    Komatsu, Y; Nogami, A; Hocini, M; Morita, H; Sato, N; Marijon, E; Arentz, T; Yli-Maeyry, S; Onishi, Y; Kowase, S; Duchateau, J; Benali, K; Takase, T; Hosaka, Y; Takei, A; Nakajima, I; Kawamura, M; Inden, Y; Ieda, M; Aonuma, K; Haissaguerre, M

    JACC-CLINICAL ELECTROPHYSIOLOGY   Vol. 10 ( 1 ) page: 1 - 12   2024.1

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  40. Association Between Catheter Ablation for Nonparoxysmal Atrial Fibrillation and Functional Mitral Regurgitation in Patients With Heart Failure With Preserved Ejection Fraction

    Yamauchi, R; Morishima, I; Okumura, K; Kanzaki, Y; Morita, Y; Watanabe, N; Furui, K; Yoshioka, N; Shibata, N; Miyazawa, H; Shimojo, K; Imaoka, T; Sakamoto, G; Goto, H; Ohi, T; Yanagisawa, S; Inden, Y; Murohara, T

    AMERICAN JOURNAL OF CARDIOLOGY   Vol. 207   page: 192 - 201   2023.11

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  41. Visualization of Repolarization Heterogeneity in Brugada Syndrome A Quantitative Analysis of Unipolar Electrogram T-Wave

    Yanagisawa, S; Inden, Y; Goto, T; Kondo, S; Tachi, M; Iwawaki, T; Hiramatsu, K; Yamauchi, R; Shimojo, M; Tsuji, Y; Shibata, R; Murohara, T

    JACC-CLINICAL ELECTROPHYSIOLOGY   Vol. 9 ( 11 ) page: 2401 - 2411   2023.11

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  42. Initial multicenter clinical experience with the first-generation endoscopic guided laser balloon in Japan

    Goya, M; Hirao, K; Aonuma, K; Nogami, A; Yamane, T; Yamauchi, Y; Okishige, K; Yotsukura, A; Kimura, M; Naito, S; Kato, R; Nitta, J; Inaba, O; Satomi, K; Morita, N; Kobayashi, Y; Inden, Y; Yoshida, Y; Kakita, K; Kobori, A; Kusano, K; Inoue, K; Masuda, M; Hiroshima, K; Koyama, J; Kumagai, K; Okumura, K; HeartLight Study Investigators

    JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY   Vol. 66 ( 7 ) page: 1713 - 1721   2023.10

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  43. Lethal ventricular arrhythmia due to entrectinib-induced Brugada syndrome: a case report and literature review

    Futamura, K; Hase, T; Tanaka, A; Sakai, Y; Okachi, S; Shibata, H; Ushijima, F; Hashimoto, T; Nakashima, K; Ito, K; Yamamoto, T; Numaguchi, A; Inden, Y; Ishii, M

    INTERNATIONAL CANCER CONFERENCE JOURNAL   Vol. 12 ( 4 ) page: 299 - 304   2023.10

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  44. Subclinical persistent atrial fibrillation in left atrium behind the ectopic atrial rhythm on electrocardiogram.

    Mizutani Y, Yanagisawa S, Makino Y, Kanashiro M, Inden Y, Murohara T

    HeartRhythm case reports   Vol. 9 ( 9 ) page: 685 - 688   2023.9

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    DOI: 10.1016/j.hrcr.2023.07.005

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  45. Different time course effect of autonomic nervous modulation after cryoballoon and hotballoon catheter ablations for paroxysmal atrial fibrillation

    Suzuki, N; Inden, Y; Yanagisawa, S; Shimizu, Y; Narita, S; Hiramatsu, K; Yamauchi, R; Watanabe, R; Tsurumi, N; Shimojo, M; Suga, K; Tsuji, Y; Shibata, R; Murohara, T

    JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY     2023.6

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  46. Evaluation of the direction and extent of ice formation during cryoballoon ablation: an experimental study

    Mizutani, Y; Yanagisawa, S; Fujiwara, G; Kasai, Y; Tajima, A; Makino, Y; Suzuki, H; Hiramatsu, T; Ichimiya, H; Uchida, Y; Watanabe, J; Kanashiro, M; Inden, Y; Murohara, T

    JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY   Vol. 66 ( 4 ) page: 981 - 989   2023.6

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  47. Transmural lesion formation after left atrial roof cryoballoon ablation: Insight from simultaneous high-density epicardial mapping

    Kato, H; Yanagisawa, S; Sakurai, T; Murakami, H; Inden, Y; Murohara, T

    HEART RHYTHM O2   Vol. 4 ( 5 ) page: 329 - 332   2023.5

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  48. Successful catheter ablation for a dominant atrial fibrillation driver manifested after box isolation using a novel mapping system in a patient with persistent atrial fibrillation.

    Tachi M, Teraoka T, Hayashi K, Yanagisawa S, Inden Y, Murohara T

    HeartRhythm case reports   Vol. 9 ( 5 ) page: 319 - 323   2023.5

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    DOI: 10.1016/j.hrcr.2023.02.010

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  49. Catheter ablation for atrial fibrillation in heart failure: Getting closer to the full picture in the whole population

    Yanagisawa, S; Inden, Y; Murohara, T

    INTERNATIONAL JOURNAL OF CARDIOLOGY   Vol. 376   page: 81 - 82   2023.4

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  50. The ridge line of left pulmonary vein isolation from left atrial appendage can subsequently increase the completion rate of the mitral isthmus block line

    Hori, H; Kaneko, S; Fujita, M; Nagai, S; Ito, R; Shirai, Y; Adachi, K; Suzuki, N; Suzuki, J; Kondo, K; Yamauchi, R; Haga, T; Tatami, Y; Ohashi, T; Kubota, R; Shinoda, M; Tanaka, A; Inden, Y; Murohara, T

    JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY   Vol. 66 ( 3 ) page: 673 - 681   2023.4

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  51. A rare case of delayed complete lead dislodgement after deep septal pacing: A hidden risk of the specific procedure

    Watanabe, R; Inden, Y; Yanagisawa, S; Narita, Y; Hiramatsu, K; Yamauchi, R; Tsurumi, N; Suzuki, N; Shimojo, M; Suga, K; Tsuji, Y; Murohara, T

    PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY   Vol. 46 ( 4 ) page: 341 - 345   2023.4

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  52. A novel practical algorithm using machine learning to differentiate outflow tract ventricular arrhythmia origins

    Shimojo, M; Inden, Y; Yanagisawa, S; Suzuki, N; Tsurumi, N; Watanabe, R; Nakagomi, T; Okajima, T; Suga, K; Tsuji, Y; Murohara, T

    JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY   Vol. 34 ( 3 ) page: 627 - 637   2023.3

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  53. HotBalloon Pulmonary Vein Isolation Registry Study - Real-World Efficacy and Safety of HotBalloon Ablation -

    Yamasaki, H; Nakahara, S; Sohara, H; Yoshida, Y; Kohno, T; Shimane, A; Miyauchi, Y; Kusano, K; Inden, Y; Yamane, T; Aonuma, K

    CIRCULATION JOURNAL   Vol. 87 ( 1 ) page: 65 - +   2023.1

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  54. Stereotactic radiotherapy for ventricular tachycardia: A study protocol.

    Kawamura M, Shimojo M, Inden Y, Kamomae T, Okudaira K, Komada T, Aoki S, Shindo Y, Yasui R, Yanagi Y, Okumura M, Yamada T, Kozai Y, Oie Y, Kato Y, Ishihara S, Murohara T, Naganawa S

    F1000Research   Vol. 12   page: 798   2023

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    DOI: 10.12688/f1000research.138758.2

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  55. Higher F-wave frequency associates with poor procedural success rate after Maze procedure

    Usui, R; Mutsuga, M; Narita, Y; Tokuda, Y; Terazawa, S; Ito, H; Uchida, W; Inden, Y; Murohara, T; Usui, A

    GENERAL THORACIC AND CARDIOVASCULAR SURGERY   Vol. 70 ( 12 ) page: 997 - 1004   2022.12

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  56. Efficacy and feasibility of cryoballoon ablation for atrial fibrillation in patients with heart failure: A large-scale multicenter study

    Yanagisawa, S; Suzuki, H; Kanzaki, Y; Ishikawa, S; Kamikubo, Y; Okumura, S; Kato, H; Mizutani, Y; Murase, Y; Nakasuka, K; Warita, S; Sekimoto, S; Takemoto, Y; Takasugi, N; Ohguchi, S; Senga, M; Yokoi, K; Shibata, R; Inden, Y; Murohara, T

    JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY   Vol. 33 ( 12 ) page: 2447 - 2464   2022.12

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  57. A case of successful catheter ablation of blocked atrial bigeminy and bradycardia with the recovery of normal sinus rhythm and myocardial reverse remodeling

    Sugiyama, T; Mizutani, Y; Yanagisawa, S; Kanashiro, M; Inden, Y; Murohara, T

    CLINICAL CASE REPORTS   Vol. 10 ( 12 ) page: e6791   2022.12

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  58. JCS/JHRS 2020 Guideline on Pharmacotherapy of Cardiac Arrhythmias

    Ono, K; Iwasaki, YK; Akao, M; Ikeda, T; Ishii, K; Inden, Y; Kusano, K; Kobayashi, Y; Koretsune, Y; Sasano, T; Sumitomo, N; Takahashi, N; Niwano, S; Hagiwara, N; Hisatome, I; Furukawa, T; Honjo, H; Maruyama, T; Murakawa, Y; Yasaka, M; Watanabe, E; Aiba, T; Amino, M; Itoh, H; Ogawa, H; Okumura, Y; Aoki-Kamiya, C; Kishihara, J; Kodani, E; Komatsu, T; Sakamoto, Y; Satomi, K; Shiga, T; Shinohara, T; Suzuki, A; Suzuki, S; Sekiguchi, Y; Nagase, S; Hayami, N; Harada, M; Fujino, T; Makiyama, T; Maruyama, M; Miake, J; Muraji, S; Murata, H; Morita, N; Yokoshiki, H; Yoshioka, K; Yodogawa, K; Inoue, H; Okumura, K; Kimura, T; Tsutsui, H; Shimizu, W

    JOURNAL OF ARRHYTHMIA   Vol. 38 ( 6 ) page: 833 - 973   2022.12

  59. Regional left atrial conduction velocity in the anterior wall is associated with clinical recurrence of atrial fibrillation after catheter ablation: efficacy in combination with the ipsilateral low voltage area

    Ohguchi, S; Inden, Y; Yanagisawa, S; Fujita, R; Yasuda, K; Katagiri, K; Oguri, M; Murohara, T

    BMC CARDIOVASCULAR DISORDERS   Vol. 22 ( 1 ) page: 457   2022.11

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  60. JCS/JHRS 2020 Guideline on Pharmacotherapy of Cardiac Arrhythmias Reviewed

    Ono, K; Iwasaki, YK; Akao, M; Ikeda, T; Ishii, K; Inden, Y; Kusano, K; Kobayashi, Y; Koretsune, Y; Sasano, T; Sumitomo, N; Takahashi, N; Niwano, S; Hagiwara, N; Hisatome, I; Furukawa, T; Honjo, H; Maruyama, T; Murakawa, Y; Yasaka, M; Watanabe, E; Aiba, T; Amino, M; Itoh, H; Ogawa, H; Okumura, Y; Aoki-Kamiya, C; Kishihara, J; Kodani, E; Komatsu, T; Sakamoto, Y; Satomi, K; Shiga, T; Shinohara, T; Suzuki, A; Suzuki, S; Sekiguchi, Y; Nagase, S; Hayami, N; Harada, M; Fujino, T; Makiyama, T; Maruyama, M; Miake, J; Muraji, S; Murata, H; Morita, N; Yokoshiki, H; Yoshioka, K; Yodogawa, K; Inoue, H; Okumura, K; Kimura, T; Tsutsui, H; Shimizu, W

    CIRCULATION JOURNAL   Vol. 86 ( 11 ) page: 1790 - 1924   2022.11

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  61. Septal coronary artery fistula after left bundle branch area pacing assessed by multi-imaging modalities and shunt volume quantification

    Kato, H; Yanagisawa, S; Ota, R; Murakami, H; Kada, K; Tsuboi, N; Inden, Y; Murohara, T

    PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY   Vol. 45 ( 11 ) page: 1299 - 1302   2022.11

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  62. Impact of synchronized left ventricular pacing rate on risk for ventricular tachyarrhythmias after cardiac resynchronization therapy in patients with heart failure

    Okajima, T; Inden, Y; Yanagisawa, S; Suga, K; Shimojo, M; Nakagomi, T; Tsurumi, N; Watanabe, R; Suzuki, N; Shibata, R; Murohara, T

    JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY   Vol. 65 ( 1 ) page: 239 - 249   2022.10

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  63. Depolarization and repolarization dynamics after His-bundle pacing: Comparison with right ventricular pacing and native ventricular conduction

    Yanagisawa, S; Inden, Y; Watanabe, R; Tsurumi, N; Suzuki, N; Nakagomi, T; Shimojo, M; Okajima, T; Riku, S; Furui, K; Suga, K; Shibata, R; Murohara, T

    ANNALS OF NONINVASIVE ELECTROCARDIOLOGY   Vol. 27 ( 5 ) page: e12991   2022.9

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  64. Characteristics of successful reactive atrial-based antitachycardia pacing in patients with cardiac implantable electronic devices: History of catheter ablation of atrial fibrillation as a predictor of high treatment efficacy

    Nakagomi, T; Inden, Y; Yanagisawa, S; Suzuki, N; Tsurumi, N; Watanabe, R; Shimojo, M; Okajima, T; Suga, K; Shibata, R; Murohara, T

    JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY   Vol. 33 ( 7 ) page: 1515 - 1528   2022.7

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  65. Short coupling interval with high burden of atrial ectopy predicts recurrence after atrial fibrillation ablation Reviewed

    Okajima, T; Inden, Y; Yanagisawa, S; Imai, H; Murase, Y; Ogawa, Y; Kawaguchi, K; Murohara, T

    HEART AND VESSELS   Vol. 37 ( 5 ) page: 775 - 787   2022.5

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  66. Identification of high priority focal activations in persistent atrial fibrillation using a novel mapping strategy Reviewed

    Shimojo, M; Inden, Y; Yanagisawa, S; Riku, S; Suga, K; Furui, K; Nakagomi, T; Okajima, T; Shibata, R; Murohara, T

    HEART AND VESSELS   Vol. 37 ( 5 ) page: 840 - 853   2022.5

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  67. Cryoballoon ablation for atrial fibrillation without the use of a contrast medium: a combination of the intracardiac echocardiography and pressure wave monitoring guided approach Reviewed

    Makino, Y; Mizutani, Y; Yamashita, D; Yonekawa, J; Satake, A; Kurobe, M; Hiramatsu, T; Ichimiya, H; Uchida, Y; Watanabe, J; Kanashiro, M; Ichimiya, S; Yanagisawa, S; Inden, Y; Murohara, T

    HEART AND VESSELS   Vol. 37 ( 5 ) page: 765 - 774   2022.5

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  68. Evaluation of the Novel Automated Anti-Tachycardia Pacing Algorithm Successfully Terminating Sustained Monomorphic Ventricular Tachycardia in an Electrophysiology Study A Case Report

    Yanagisawa, S; Inden, Y; Okajima, T; Nakagomi, T; Shimojo, M; Watanabe, R; Tsurumi, N; Suzuki, N; Suga, K; Shibata, R; Murohara, T

    INTERNATIONAL HEART JOURNAL   Vol. 63 ( 3 ) page: 633 - 638   2022.5

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  69. Very long-term clinical outcomes after percutaneous coronary intervention for complex vs non-complex lesions: 10-year outcomes following sirolimus-eluting stent implantation

    Riku, S; Suzuki, S; Yokoi, T; Sakaguchi, T; Yamamoto, T; Jinno, Y; Tanaka, A; Ishii, H; Inden, Y; Murohara, T

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 84 ( 2 ) page: 352 - 365   2022.5

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  70. Long P-wave duration immediately after pulmonary vein isolation on radiofrequency catheter ablation for atrial fibrillation predicts clinical recurrence: correlation with atrial remodeling in persistent atrial fibrillation Reviewed

    Ohguchi, S; Inden, Y; Yanagisawa, S; Shigematsu, T; Yasuda, K; Katagiri, K; Oguri, M; Murohara, T

    HEART AND VESSELS   Vol. 37 ( 3 ) page: 476 - 488   2022.3

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  71. Impact of Preoperative Nutritional Status on the Outcome of Catheter Ablation for Atrial Fibrillation Reviewed

    Furui, K; Morishima, I; Morita, Y; Kanzaki, Y; Takagi, K; Nagai, H; Watanabe, N; Yoshioka, N; Yamauchi, R; Miyazawa, H; Yanagisawa, S; Inden, Y; Murohara, T

    CIRCULATION JOURNAL   Vol. 86 ( 2 ) page: 268 - +   2022.2

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  72. Comparison of the empirical linear ablation and low voltage area-guided ablation in addition to pulmonary vein isolation in patients with persistent atrial fibrillation: a propensity score-matched analysis Reviewed

    Suzuki, N; Kaneko, S; Fujita, M; Shinoda, M; Kubota, R; Ohashi, T; Tatami, Y; Suzuki, J; Hori, H; Adachi, K; Ito, R; Shirai, Y; Yanagisawa, S; Inden, Y; Murohara, T

    BMC CARDIOVASCULAR DISORDERS   Vol. 22 ( 1 ) page: 13   2022.1

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  73. Efficacy of His Bundle Pacing on LV Relaxation and Clinical Improvement in HF and LBBB Reviewed

    Kato, H; Yanagisawa, S; Sakurai, T; Mizuno, C; Ota, R; Watanabe, R; Suga, K; Okada, T; Murakami, H; Kada, K; Inden, Y; Tsuboi, N; Murohara, T

    JACC-CLINICAL ELECTROPHYSIOLOGY   Vol. 8 ( 1 ) page: 59 - 69   2022.1

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  74. Usefulness of the Snare Technique During Leadless Pacemaker Implantation for a Patient with a Severely Dilated Right Atrium A Case Report Reviewed

    Hiramatsu, T; Mizutani, Y; Yanagisawa, S; Sugiyama, T; Yamashita, D; Tajima, A; Yonekawa, J; Makino, Y; Suzuki, H; Ichimiya, H; Uchida, Y; Watanabe, J; Kanashiro, M; Inden, Y; Murohara, T

    INTERNATIONAL HEART JOURNAL   Vol. 63 ( 1 ) page: 159 - 162   2022.1

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  75. Permanent His-bundle pacing using distal His-bundle electrogram-guided approach in patients with atrioventricular block Reviewed

    Suga, K; Kato, H; Inden, Y; Yanagisawa, S; Murakami, H; Kada, K; Tsuboi, N; Murohara, T

    PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY   Vol. 44 ( 11 ) page: 1907 - 1917   2021.11

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  76. Earliest pulmonary vein potential-guided cryoballoon ablation is associated with better clinical outcomes than conventional cryoballoon ablation: A result from two randomized clinical studies Reviewed

    Mizutani, Y; Yanagisawa, S; Kanashiro, M; Yamashita, D; Yonekawa, J; Makino, Y; Hiramatsu, T; Ichimiya, H; Uchida, Y; Watanabe, J; Ichimiya, S; Inden, Y; Murohara, T

    JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY   Vol. 32 ( 11 ) page: 2933 - 2942   2021.11

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  77. Incidence of Left Atrial Thrombus Development and Imaging Approach in Patients Scheduled for Repeat Catheter Ablation for Atrial Fibrillation Reviewed

    Yanagisawa, S; Inden, Y; Riku, S; Suga, K; Furui, K; Nakagomi, T; Shimojo, M; Okajima, T; Shibata, R; Murohara, T

    AMERICAN JOURNAL OF CARDIOLOGY   Vol. 155   page: 52 - 63   2021.9

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  78. Dynamic Changes in Electrocardiogram Parameters After Epicardial Substrate Catheter Ablation of Brugada Syndrome. Reviewed

    Mamiya K, Inden Y, Yanagisawa S, Fujii A, Tomomatsu T, Okamoto H, Riku S, Suga K, Furui K, Nakagomi T, Shibata R, Murohara T

    Circulation journal : official journal of the Japanese Circulation Society   Vol. 85 ( 8 ) page: 1283 - +   2021.8

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    DOI: 10.1253/circj.CJ-20-1060

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  79. Disappearance pattern and the last remaining earliest pulmonary vein potential during cryoballoon ablation in predicting recurrence and conduction gap site of pulmonary veins Reviewed

    Mizutani Yoshiaki, Inden Yasuya, Yanagisawa Satoshi, Kanashiro Masaaki, Makino Yuichiro, Satake Akinori, Kurobe Masanari, Ichimiya Hitoshi, Uchida Yasuhiro, Watanabe Junji, Ichimiya Satoshi, Murohara Toyoaki

    HEART AND VESSELS   Vol. 36 ( 8 ) page: 1190 - 1200   2021.8

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    DOI: 10.1007/s00380-021-01785-3

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  80. JCS/JHRS 2019 guideline on non-pharmacotherapy of cardiac arrhythmias

    Nogami, A; Kurita, T; Abe, H; Ando, K; Ishikawa, T; Imai, K; Usui, A; Okishige, K; Kusano, K; Kumagai, K; Goya, M; Kobayashi, Y; Shimizu, A; Shimizu, W; Shoda, M; Sumitomo, N; Seo, Y; Takahashi, A; Tada, H; Naito, S; Nakazato, Y; Nishimura, T; Nitta, T; Niwano, S; Hagiwara, N; Murakawa, Y; Yamane, T; Aiba, T; Inoue, K; Iwasaki, Y; Inden, Y; Uno, K; Ogano, M; Kimura, M; Sakamoto, S; Sasaki, S; Satomi, K; Shiga, T; Suzuki, T; Sekiguchi, Y; Soejima, K; Takagi, M; Chinushi, M; Nishi, N; Noda, T; Hachiya, H; Mitsuno, M; Mitsuhashi, T; Miyauchi, Y; Miyazaki, A; Morimoto, T; Yamasaki, H; Aizawa, Y; Ohe, T; Kimura, T; Tanemoto, K; Tsutsui, H; Mitamura, H

    JOURNAL OF ARRHYTHMIA   Vol. 37 ( 4 ) page: 709 - 870   2021.8

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  81. Defibrillation threshold of internal cardioversion prior to ablation predicts atrial fibrillation recurrence Reviewed

    Sawasaki, K; Inden, Y; Hosoya, N; Muto, M; Murohara, T

    CLINICAL CARDIOLOGY   Vol. 44 ( 8 ) page: 1169 - 1176   2021.8

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  82. JCS/JHRS 2019 Guideline on Non-Pharmacotherapy of Cardiac Arrhythmias. Reviewed

    Nogami A, Kurita T, Abe H, Ando K, Ishikawa T, Imai K, Usui A, Okishige K, Kusano K, Kumagai K, Goya M, Kobayashi Y, Shimizu A, Shimizu W, Shoda M, Sumitomo N, Seo Y, Takahashi A, Tada H, Naito S, Nakazato Y, Nishimura T, Nitta T, Niwano S, Hagiwara N, Murakawa Y, Yamane T, Aiba T, Inoue K, Iwasaki Y, Inden Y, Uno K, Ogano M, Kimura M, Sakamoto SI, Sasaki S, Satomi K, Shiga T, Suzuki T, Sekiguchi Y, Soejima K, Takagi M, Chinushi M, Nishi N, Noda T, Hachiya H, Mitsuno M, Mitsuhashi T, Miyauchi Y, Miyazaki A, Morimoto T, Yamasaki H, Aizawa Y, Ohe T, Kimura T, Tanemoto K, Tsutsui H, Mitamura H, JCS/JHRS Joint Working Group.

    Circulation journal : official journal of the Japanese Circulation Society   Vol. 85 ( 7 ) page: 1104 - 1244   2021.7

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    DOI: 10.1253/circj.CJ-20-0637

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  83. The mechanism and prognosis of acute and late improvement in mitral regurgitation after cardiac resynchronization therapy Reviewed

    Okamoto Hiroya, Inden Yasuya, Yanagisawa Satoshi, Fujii Aya, Tomomatsu Toshiro, Mamiya Keita, Riku Shuro, Suga Kazumasa, Furui Koichi, Nakagomi Toshifumi, Shibata Rei, Murohara Toyoaki

    HEART AND VESSELS   Vol. 36 ( 7 ) page: 986 - 998   2021.7

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    DOI: 10.1007/s00380-021-01771-9

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  84. Defibrillation threshold of internal cardioversion prior to ablation predicts atrial fibrillation recurrence Reviewed

    Sawasaki K, Inden Y, Hosoya N, Muto M, Murohara T

    Clin Cardiol     2021.6

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  85. Coagulation Response and Prothrombotic Effect of Uninterrupted Oral Anticoagulant Administration After Catheter Ablation for VT

    Yanagisawa, S; Inden, Y; Riku, S; Furui, K; Suga, K; Nakagomi, T; Shimojo, M; Okajima, T; Watanabe, R; Tsurumi, N; Suzuki, N; Shibata, R; Murohara, T

    JACC-CLINICAL ELECTROPHYSIOLOGY   Vol. 8 ( 6 ) page: 735 - 748   2021.6

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  86. A case of heart failure complicated with double ventricular response triggered by beta blocker. Reviewed

    Kazama S, Kondo T, Suga K, Yanagisawa S, Morimoto R, Okumura T, Inden Y, Murohara T

    HeartRhythm case reports   Vol. 7 ( 3 ) page: 174 - 177   2021.3

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    DOI: 10.1016/j.hrcr.2020.12.004

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  87. Early improvement of daily physical activity after catheter ablation for atrial fibrillation in an accelerometer assessment: A prospective pilot study Reviewed

    Yanagisawa Satoshi, Inden Yasuya, Fujii Aya, Sakamoto Yusuke, Tomomatsu Toshiro, Mamiya Keita, Okamoto Hiroya, Murohara Toyoaki, Shibata Rei

    ANNALS OF NONINVASIVE ELECTROCARDIOLOGY   Vol. 26 ( 1 ) page: e12807   2021.1

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    DOI: 10.1111/anec.12807

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  88. CORRIGENDUM: JCS/JHRS 2019 Guideline on Non-Pharmacotherapy of Cardiac Arrhythmias.

    Nogami A, Kurita T, Abe H, Ando K, Ishikawa T, Imai K, Usui A, Okishige K, Kusano K, Kumagai K, Goya M, Kobayashi Y, Shimizu A, Shimizu W, Shoda M, Sumitomo N, Seo Y, Takahashi A, Tada H, Naito S, Nakazato Y, Nishimura T, Nitta T, Niwano S, Hagiwara N, Murakawa Y, Yamane T, Aiba T, Inoue K, Iwasaki Y, Inden Y, Uno K, Ogano M, Kimura M, Sakamoto SI, Sasaki S, Satomi K, Shiga T, Suzuki T, Sekiguchi Y, Soejima K, Takagi M, Chinushi M, Nishi N, Noda T, Hachiya H, Mitsuno M, Mitsuhashi T, Miyauchi Y, Miyazaki A, Morimoto T, Yamasaki H, Aizawa Y, Ohe T, Kimura T, Tanemoto K, Tsutsui H, Mitamura H, JCS/JHRS Joint Working Group.

    Circulation journal : official journal of the Japanese Circulation Society   Vol. 85 ( 9 ) page: 1692 - 1700   2021

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    DOI: 10.1253/circj.CJ-66-0196

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  89. Improved Risk Stratification of Patients With Brugada Syndrome by the New Japanese Circulation Society Guideline - A Multicenter Validation Study - Reviewed

    Wakamiya Akinori, Kamakura Tsukasa, Shinohara Tetsuji, Yodogawa Kenji, Murakoshi Nobuyuki, Morita Hiroshi, Takahashi Naohiko, Inden Yasuya, Shimizu Wataru, Nogami Akihiko, Horie Minoru, Nakajima Kenzaburo, Kataoka Naoya, Wada Mitsuru, Yamagata Kenichiro, Ishibashi Kohei, Inoue Yuko, Miyamoto Koji, Nagase Satoshi, Noda Takashi, Aiba Takeshi, Yasuda Satoshi, Ieda Masaki, Kusano Kengo

    CIRCULATION JOURNAL   Vol. 84 ( 12 ) page: 2158 - +   2020.12

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  90. Safety and efficacy of first-line cryoablation for para-hisian ventricular arrhythmias using a cryomapping protocol approach: A case series Reviewed

    Mizutani Yoshiaki, Yanagisawa Satoshi, Kanashiro Masaaki, Inden Yasuya, Murohara Toyoaki

    CLINICAL CASE REPORTS   Vol. 8 ( 12 ) page: 3247 - 3252   2020.12

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    DOI: 10.1002/ccr3.3401

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  91. Autopsy evaluation of the implantation site of a His bundle pacing lead demonstrating selective capture Reviewed

    Kato Hiroyuki, Igawa Osamu, Suga Kazumasa, Murakami Hisashi, Kada Kenji, Tsuboi Naoya, Yanagisawa Satoshi, Inden Yasuya, Murohara Toyoaki

    PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY   Vol. 43 ( 11 ) page: 1412 - 1416   2020.11

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    DOI: 10.1111/pace.13989

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  92. The impact of the dominant frequency of body surface electrocardiography in patients with persistent atrial fibrillation Reviewed International coauthorship

    Murase Yosuke, Inden Yasuya, Shibata Rei, Yanagisawa Satoshi, Fujii Aya, Ando Monami, Otake Noriaki, Takenaka Masaki, Funabiki Junya, Sakamoto Yusuke, Murohara Toyoaki

    HEART AND VESSELS   Vol. 35 ( 7 ) page: 967 - 976   2020.7

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    DOI: 10.1007/s00380-020-01563-7

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  93. Periprocedural Management of Cardiac Tamponade During Catheter Ablation for AF Under Uninterrupted DOAC and Warfarin Reviewed

    Yanagisawa Satoshi, Inden Yasuya, Ohguchi Shiou, Nagao Tomoyuki, Fujii Aya, Tomomatsu Toshiro, Mamiya Keita, Okamoto Hiroya, Sakamoto Yusuke, Shibata Rei, Murohara Toyoaki

    JACC-CLINICAL ELECTROPHYSIOLOGY   Vol. 6 ( 7 ) page: 786 - 795   2020.7

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  94. Prospective comparison of periprocedural coagulation markers among uninterrupted anticoagulants for atrial fibrillation ablation Reviewed

    Nagao Tomoyuki, Higo Sayaka, Suzuki Hitomi, Teshima Yuto, Matsunaga Syun, Harada Kazuhiro, Shinoda Norihiro, Harada Ken, Kato Masataka, Marui Nobuyuki, Amano Tetsuya, Inden Yasuya, Murohara Toyoaki

    HEART RHYTHM   Vol. 17 ( 3 ) page: 391 - 397   2020.3

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    DOI: 10.1016/j.hrthm.2019.10.015

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  95. Electrocardiogram characteristics of P wave associated with successful pulmonary vein isolation in patients with paroxysmal atrial fibrillation: Significance of changes in P-wave duration and notched P wave Reviewed

    Yanagisawa Satoshi, Inden Yasuya, Okamoto Hiroya, Fujii Aya, Sakamoto Yusuke, Mamiya Keita, Tomomatsu Toshiro, Shibata Rei, Murohara Toyoaki

    ANNALS OF NONINVASIVE ELECTROCARDIOLOGY   Vol. 25 ( 2 ) page: e12712   2020.3

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    DOI: 10.1111/anec.12712

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  96. Long-term prognosis of patients with J-wave syndrome Reviewed

    Kamakura Tsukasa, Shinohara Tetsuji, Yodogawa Kenji, Murakoshi Nobuyuki, Morita Hiroshi, Takahashi Naohiko, Inden Yasuya, Shimizu Wataru, Nogami Akihiko, Horie Minoru, Aiba Takeshi, Kusano Kengo

    HEART   Vol. 106 ( 4 ) page: 299 - 306   2020.2

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    DOI: 10.1136/heartjnl-2019-315007

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  97. Earliest pulmonary vein potential-guided cryoballoon ablation for atrial fibrillation Reviewed

    Mizutani Yoshiaki, Kanashiro Masaaki, Makino Yuichiro, Satake Akinori, Suzuki Wataru, Kurobe Masanari, Mizutani Kouji, Ichimiya Hitoshi, Uchida Yasuhiro, Watanabe Junji, Ichimiya Satoshi, Inden Yasuya, Murohara Toyoaki

    HEART AND VESSELS   Vol. 35 ( 2 ) page: 232 - 238   2020.2

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    DOI: 10.1007/s00380-019-01471-5

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  98. Anatomical assessment of crosstalk phenomenon during laser balloon ablation with imaging in a patient with unusual atrial hypertrophy Reviewed

    Yanagisawa Satoshi, Inden Yasuya, Okamoto Hiroya, Tomomatsu Toshiro, Fujii Aya, Mamiya Keita, Shibata Rei, Murohara Toyoaki

    JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY   Vol. 57 ( 1 ) page: 157 - 159   2020.1

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    DOI: 10.1007/s10840-019-00632-w

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  99. Hot-Balloon Pulmonary Vein Isolation Registry Study (HARVEST Study): The Efficacy and Safety Data of SATAKE Hot-Balloon in the Real World Reviewed

    Nakahara Shiro, Sohara Hiroshi, Nakamura Yoshinori, Yamasaki Hiro, Yoshida Yukihiko, Kohno Tsunesuke, Shimane Akira, Miyauchi Yasushi, Okano Yoshifumi, Shioji Keisuke, Fukae Satoki, Satake Shutaro, Ozawa Tomoya, Kobori Atsushi, Kamijima Toru, Muto Masahiro, Nagashima Koichi, Naito Shigeto, Usui Tatsuya, Harada Masahide, Sasaki Takeshi, Watanabe Tetsuya, Fukata Mitsuhiro, Yamane Teiichi, Oba Kageyuki, Kimura Masaomi, Murakami Hisashi, Sugiura Hirotaka, Kusano Kengo, Inden Yasuya, Aonuma Kazutaka

    CIRCULATION   Vol. 140 ( 25 ) page: E990 - E991   2019.12

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  100. Prothrombotic Responses After Catheter Ablation for Atrial Fibrillation During Uninterrupted Oral Anticoagulant Agent Administration Reviewed

    JACC-CLINICAL ELECTROPHYSIOLOGY   Vol. 5 ( 12 ) page: 1418 - 1427   2019.12

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    DOI: 10.1016/j.jacep.2019.09.002

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  101. Study design and protocol for evaluating the long-term prognosis of patients receiving his bundle pacing: A multicenter observational study Reviewed

    Yanagisawa Satoshi, Inden Yasuya, Kato Hiroyuki, Suzuki Hirohiko, Fujita Masaya, Ishikawa Shinji, Kanzaki Yasunori, Kamikubo Yosuke, Murase Yosuke, Murohara Toyoaki, Shibata Rei

    JOURNAL OF ARRHYTHMIA   Vol. 35 ( 5 ) page: 760 - 765   2019.10

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    DOI: 10.1002/joa3.12229

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  102. T-wave changes of cardiac memory caused by frequent premature ventricular contractions originating from the right ventricular outflow tract Reviewed

    Sakamoto Yusuke, Inden Yasuya, Okamoto Hiroya, Mamiya Keita, Tomomatsu Toshiro, Fujii Aya, Yanagisawa Satoshi, Shibata Rei, Hirai Makoto, Murohara Toyoaki

    JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY   Vol. 30 ( 9 ) page: 1549 - 1556   2019.9

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    DOI: 10.1111/jce.14008

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  103. Differences in prothrombotic response between the uninterrupted and interrupted apixaban therapies in patients undergoing cryoballoon ablation for paroxysmal atrial fibrillation: a randomized controlled study

    Ando, M; Inden, Y; Yoshida, Y; Sairaku, A; Yanagisawa, S; Suzuki, H; Watanabe, R; Takenaka, M; Maeda, M; Murohara, T

    HEART AND VESSELS   Vol. 34 ( 9 ) page: 1533 - 1541   2019.9

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  104. Differences in prothrombotic response between the uninterrupted and interrupted apixaban therapies in patients undergoing cryoballoon ablation for paroxysmal atrial fibrillation: a randomized controlled study (vol 34, pg 1533, 2019)

    Ando, M; Inden, Y; Yoshida, Y; Sairaku, A; Yanagisawa, S; Suzuki, H; Watanabe, R; Takenaka, M; Maeda, M; Murohara, T

    HEART AND VESSELS   Vol. 34 ( 9 ) page: 1542 - 1542   2019.9

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  105. Discontinuous contraction in the left ventricle assessed by 2-D speckle tracking echocardiography benefits from CRT Reviewed

    Fujii Aya, Inden Yasuya, Yanagisawa Satoshi, Mamiya Keita, Okamoto Hiroya, Sakamoto Yusuke, Tomomatsu Toshiro, Shibata Rei, Murohara Toyoaki

    PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY   Vol. 42 ( 9 ) page: 1204 - 1212   2019.9

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    DOI: 10.1111/pace.13759

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  106. Identification of precise accessory pathway using ultra-high-resolution three-dimensional mapping system: utility and feasibility in preliminary experience

    Yanagisawa, S; Inden, Y; Fujii, A; Sakamoto, Y; Ichiyanagi, H; Shibata, R; Murohara, T

    JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY   Vol. 55 ( 2 ) page: 241 - 242   2019.8

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  107. His bundle pacing with unusual automaticity

    Yanagisawa, S; Inden, Y; Shibata, R; Murohara, T

    JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY   Vol. 30 ( 6 ) page: 966 - 968   2019.6

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  108. Clinical significance of the timing of early recurrence of atrial arrhythmia after pulmonary vein isolation: a two-institution clinical study.

    Murase Y, Inden Y, Imai H, Kyo S, Yanagisawa S, Fujii A, Sakamoto Y, Tomomatsu T, Murohara T

    Heart and vessels   Vol. 34 ( 5 ) page: 842 - 850   2019.5

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    DOI: 10.1007/s00380-018-1295-1

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  109. Adjacentmultiple accessory pathways demonstrated on ultra-high-resolution mapping

    Yanagisawa, S; Inden, Y; Murohara, T

    EUROPACE   Vol. 21 ( 5 ) page: 723 - 723   2019.5

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  110. Impact of periprocedural anticoagulation therapy on the incidence of silent stroke after atrial fibrillation ablation in patients receiving direct oral anticoagulants: uninterrupted vs. interrupted by one dose strategy.

    Nagao T, Suzuki H, Matsunaga S, Nishikawa Y, Harada K, Mamiya K, Shinoda N, Harada K, Kato M, Marui N, Amano T, Inden Y, Murohara T

    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology   Vol. 21 ( 4 ) page: 590 - 597   2019.4

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    DOI: 10.1093/europace/euy224

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  111. Myocardial viability as shown by left ventricular lead pacing threshold and improved dyssynchrony by QRS narrowing predicts the response to cardiac resynchronization therapy.

    Takenaka M, Inden Y, Yanagisawa S, Fujii A, Ando M, Funabiki J, Murase Y, Otake N, Sakamoto Y, Shibata R, Murohara T

    Journal of cardiovascular electrophysiology   Vol. 30 ( 3 ) page: 311 - 319   2019.3

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    DOI: 10.1111/jce.13806

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  112. Atypical Fast-Slow Atrioventricular Nodal Reentrant Tachycardia Utilizing a Slow Pathway Extending to the Inferolateral Right Atrium.

    Kaneko Y, Nakajima T, Nogami A, Inden Y, Asakawa T, Morishima I, Mizukami A, Iizuka T, Tamura S, Ota C, Kanzaki Y, Nakagawa K, Suzuki M, Kurabayashi M

    Circulation reports   Vol. 1 ( 2 ) page: 46 - 54   2019.1

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    DOI: 10.1253/circrep.CR-18-0016

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  113. Uninterrupted Direct Oral Anticoagulant and Warfarin Administration in Elderly Patients Undergoing Catheter Ablation for Atrial Fibrillation: A Comparison With Younger Patients.

    Yanagisawa S, Inden Y, Fujii A, Ando M, Funabiki J, Murase Y, Takenaka M, Otake N, Ikai Y, Sakamoto Y, Shibata R, Murohara T

    JACC. Clinical electrophysiology   Vol. 4 ( 5 ) page: 592 - 600   2018.5

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    DOI: 10.1016/j.jacep.2018.02.013

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  114. Comparison of uninterrupted anticoagulation with dabigatran etexilate or warfarin in the periprocedural period for atrial fibrillation catheter ablation: Results of the Japanese subgroup of the RE-CIRCUIT trial

    Yoshida Yukihiko, Watarai Masato, Fujii Kenshi, Shimizu Wataru, Satomi Kazuhiro, Inden Yasuya, Murakami Yoshimasa, Murakami Masato, Iwasa Atsushi, Kimura Masaomi, Yamada Nobuko, Nakagawa Tomofumi, Nordaby Matias, Okumura Ken

    JOURNAL OF ARRHYTHMIA   Vol. 34 ( 2 ) page: 148 - 157   2018.4

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    DOI: 10.1002/joa3.12024

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  115. Head-to-head comparison of acute and chronic pulmonary vein stenosis for cryoballoon versus radiofrequency ablation

    Watanabe Ryo, Sairaku Akinori, Yoshida Yukihiko, Nanasato Mamoru, Kamiya Hiroki, Suzuki Hirohiko, Ogura Yasuhiro, Aoyama Yutaka, Maeda Mayuho, Ando Monami, Eguchi Shunsuke, Inden Yasuya, Kihara Yasuki, Murohara Toyoaki

    PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY   Vol. 41 ( 4 ) page: 376 - 382   2018.4

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    DOI: 10.1111/pace.13293

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  116. Renal function and risk of stroke and bleeding in patients undergoing catheter ablation for atrial fibrillation: Comparison between uninterrupted direct oral anticoagulants and warfarin administration

    Yanagisawa Satoshi, Inden Yasuya, Fujii Aya, Ando Monami, Funabiki Junya, Murase Yosuke, Takenaka Masaki, Otake Noriaki, Ikai Yoshihiro, Sakamoto Yusuke, Shibata Rei, Murohara Toyoaki

    HEART RHYTHM   Vol. 15 ( 3 ) page: 348 - 354   2018.3

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    DOI: 10.1016/j.hrthm.2017.10.033

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  117. Assessment of autonomic nervous system modulation after novel catheter ablation techniques for atrial fibrillation using multiple short-term electrocardiogram recordings

    Yanagisawa Satoshi, Inden Yasuya, Fujii Aya, Kamikubo Yosuke, Kanzaki Yasunori, Ando Monami, Funabiki Junya, Murase Yosuke, Takenaka Masaki, Otake Noriaki, Ikai Yoshihiro, Sakamoto Yusuke, Shibata Rei, Murohara Toyoaki

    JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY   Vol. 51 ( 1 ) page: 35 - 44   2018.1

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    DOI: 10.1007/s10840-017-0295-x

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  118. Different rate-dependent responses between J waves and the notches on an epicardial local electrogram in a patient with idiopathic ventricular fibrillation.

    Kamikubo Y, Inden Y, Nagao T, Aizawa Y, Murohara T

    HeartRhythm case reports   Vol. 3 ( 9 ) page: 427 - 430   2017.9

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    DOI: 10.1016/j.hrcr.2017.06.010

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  119. Monitoring of anti-Xa activity and factors related to bleeding events: A study in Japanese patients with nonvalvular atrial fibrillation receiving rivaroxaban

    Sakaguchi Teruhiro, Osanai Hiroyuki, Murase Yosuke, Ishii Hideki, Nakashima Yoshihito, Asano Hiroshi, Suzuki Susumu, Takefuji Mikito, Inden Yasuya, Sakai Kazuyoshi, Murohara Toyoaki, Ajioka Masayoshi

    JOURNAL OF CARDIOLOGY   Vol. 70 ( 3-4 ) page: 244 - 249   2017.9

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    DOI: 10.1016/j.jjcc.2016.11.013

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  120. Vagal response in cryoballoon ablation of atrial fibrillation and autonomic nervous system: Utility of epicardial adipose tissue location

    Yanagisawa Satoshi, Inden Yasuya, Mizutani Yoshiaki, Fujii Aya, Kamikubo Yosuke, Kanzaki Yasunori, Ando Monami, Funabiki Junya, Murase Yosuke, Takenaka Masaki, Otake Noriaki, Hattori Tetsuyoshi, Shibata Rei, Murohara Toyoaki

    JOURNAL OF ARRHYTHMIA   Vol. 33 ( 4 ) page: 275 - 282   2017.8

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    DOI: 10.1016/j.joa.2017.03.001

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  121. Tachycardia-Induced J-Wave Changes in Patients With and Without Idiopathic Ventricular Fibrillation

    Aizawa Yoshiyasu, Takatsuki Seiji, Nishiyama Takahiko, Kimura Takehiro, Kohsaka Shun, Kaneko Yoshiaki, Inden Yasuya, Takahashi Naohiko, Nagase Satoshi, Aizawa Yoshifusa, Fukuda Keichi

    CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY   Vol. 10 ( 7 )   2017.7

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    DOI: 10.1161/CIRCEP.117.005214

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  122. Impaired renal function is associated with recurrence after cryoballoon catheter ablation for paroxysmal atrial fibrillation: A potential effect of non-pulmonary vein foci

    Yanagisawa Satoshi, Inden Yasuya, Kato Hiroyuki, Fujii Aya, Mizutani Yoshiaki, Ito Tadahiro, Kamikubo Yosuke, Kanzaki Yasunori, Ando Monami, Hirai Makoto, Shibata Rei, Murohara Toyoaki

    JOURNAL OF CARDIOLOGY   Vol. 69 ( 1-2 ) page: 3 - 10   2017.1

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    DOI: 10.1016/j.jjcc.2016.07.008

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  123. An ECG Index of P-Wave Force Predicts the Recurrence of Atrial Fibrillation after Pulmonary Vein Isolation Reviewed

    Kanzaki Y, Inden Y, Ando M, Kamikubo Y, Ito T, Mizutani Y, Kato H, Fujii A, Yanagisawa S, Hirai M, Murohara T

    Pacing Clin Electrophysiol   Vol. 39 ( 11 ) page: 1191-1197   2016.11

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    DOI: 10.1111/pace.12956

  124. Decrease in B-Type Natriuretic Peptide Levels and Successful Catheter Ablation for Atrial Fibrillation in Patients with Heart Failure. Reviewed

    Yanagisawa S, Inden Y, Kato H, Fujii A, Mizutani Y, Ito T, Kamikubo Y, Kanzaki Y, Hirai M, Murohara T

    Pacing Clin Electrophysiol   Vol. 39 ( 3 ) page: 225-234   2016.3

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    DOI: 10.1111/pace.12788

  125. Efficacy and safety of apixaban in the patients undergoing the ablation of atrial fibrillation. Reviewed

    Nagao T, Inden Y, Shimano M, Fujita M, Yanagisawa S, Kato H, Ishikawa S, Miyoshi A, Okumura S, Ohguchi S, Yamamoto T, Yoshida N, Hirai M, Murohara T.

    Pacing Clin Electrophysiol   Vol. 38 ( 2 ) page: 155-63   2015.2

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    DOI: 10.1111/pace.12553.

  126. Clinical characteristics and predictors of super-response to cardiac resynchronization therapy: a combination of predictive factors. Reviewed

    Yanagisawa S, Inden Y, Shimano M, Yoshida N, Fujita M, Ohguchi S, Ishikawa S, Kato H, Okumura S, Miyoshi A, Nagao T, Yamamoto T, Hirai M, Murohara T.

    Pacing Clin Electrophysiol.   Vol. 37 ( 11 ) page: 1553-64   2014.11

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    DOI: 10.1111/pace.12506.

  127. Efficacy and safety of radiofrequency catheter ablation for atrial fibrillation in chronic hemodialysis patients

    Hayashi M, Kaneko S, Shimano M, Ohashi T, Kubota R, Takeshita K, Shinoda M, Inden Y, Kanayama H, Murohara T

    Nephrol Dial Transplant   Vol. 29 ( 1 ) page: 160-7   2014.1

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    DOI: 10.1093/ndt/gft233

  128. Clinical outcome of implantable cardioverter defibrillators with recalled and non-recalled leads in Japanese patients

    Yanagisawa S, Inden Y, Shimano M, Yoshida N, Ichiyanagi H, Fujita M, Ohguchi S, Ishikawa S, Kato H, Okumura S, Miyoshi A, Nagao T, Yamamoto T, Hirai M, Murohara T

    Circ J   Vol. 78 ( 2 ) page: 353-9   2014.1

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    DOI: 353-9

  129. Mechanisms with clinical implications for atrial fibrillation-associated remodeling: cathepsin K expression, regulation, and therapeutic target and biomarker

    Fujita M, Cheng XW, Inden Y, Shimano M, Yoshida N, Inoue A, Yamamoto T, Takeshita K, Kyo S, Taguchi N, Shi GP, Kuzuya M, Okumura K, Murohara T

    J Am Heart Assoc   Vol. 2 ( 6 ) page: e000503   2013.12

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    DOI: 10.1161/JAHA.113.000503

  130. Cystatin C as a predictor of mortality and cardiovascular morbidity after cardiac resynchronization therapy

    Yamamoto T, Shimano M, Inden Y, Miyata S, Inoue Y, Yoshida N, Tsuji Y, Hirai M, Murohara T

    Circ J   Vol. 77 ( 11 ) page: 2751-6   2013.8

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    DOI: 2751-6

  131. Physiological Magnetic Stimulation for Arousal of Elderly Car Driver Evaluated With Electro-Encephalogram and Spine Magnetic Field Reviewed

    Kaneo Mohri, Tsuyoshi Uchiyama, MuneoYamada, Yoshiyuki Mohri, K. Endo, T. Suzuki, Yasuya Inden

    IEEE TRANSACTIONS ON MAGNETICS,   Vol. 48 ( 11 ) page: 3505-3508   2012.11

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    DOI: 10.1109/TMAG.2012.2200457

  132. Ca(2+)-related signaling and protein phosphorylation abnormalities play central roles in a new experimental model of electrical storm.

    Tsuji Y, Hojo M, Voigt N, El-Armouche A, Inden Y, Murohara T, Dobrev D, Nattel S, Kodama I, Kamiya K.

    Circulation   Vol. 123 ( 20 ) page: 2192-2203   2011.5

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  133. Novel transitional zone index allows more accurate differentiation between idiopathic right ventricular outflow tract and aortic sinus cusp ventricular arrhythmias.

    Yoshida N, Inden Y, Uchikawa T, Kamiya H, Kitamura K, Shimano M, Tsuji Y, Hirai M, Murohara T.

    Heart Rhythm   Vol. 8 ( 3 ) page: 349-356   2011.3

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  134. Electrocardiographic and electrophysiological characteristics in idiopathicventricular arrhythmias originating from the papillary muscles in the leftventricle: relevance for catheter ablation Reviewed

    Yamada T, Doppalapudi H, McElderry HT, Okada T, Murakami Y, Inden Y, YoshidaY, Yoshida N, Murohara T, Epstein AE, Plumb VJ, Litovsky SH, Kay GN

    Circ Arrhythm Electrophysiol   Vol. 3 ( 4 ) page: 324-31   2010.8

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  135. Combined assessment of left ventricular dyssynchrony and contractility by speckled tracking strain imaging: a novel index for predicting responders to cardiac resynchronization therapy Reviewed

    Inden Y, Ito R, Yoshida N, Kamiya H, Kitamura K, Kitamura T, Shimano M, Uchikawa T, Tsuji Y, Shibata R, Hirai M, Murohara T

    Heart Rhythm   Vol. 7 ( 5 ) page: :655-61   2010.5

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  136. *Morphological characteristics of the Holter P-waves associated with pulmonary vein pacing. Reviewed

    Harata S, Inden Y, Shimano M, Uchikawa T, Mutoh M, Hirai M, Murohara T

    Europace   Vol. 12 ( 1 ) page: 124-129   2010.1

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  137. Morphological characteristics of the Holter P-waves associated with pulmonaryvein pacing Reviewed

    Harata S, Inden Y, Shimano M, Uchikawa T, Mutoh M, Hirai M, Murohara T

    Europace   Vol. 12 ( 1 ) page: 124-9   2010.1

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  138. Difference in percentage of ventricular pacing between two algorithms for minimizing ventricular pacing: results of the IDEAL RVP (Identify the Best Algorithm for Reducing Unnecessary Right Ventricular Pacing) study. Reviewed

    Murakami Y, Tsuboi N, Inden Y, Yoshida Y, Murohara T, Ihara Z, Takami M

    Europace   Vol. 12 ( 1 ) page: 96-102   2010.1

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  139. Impact of acarbose on carotid intima-media thickness in patients with newly diagnosed impaired glucose tolerance or mildtype 2 diabetes mellitus: A one-year, prospective, randomized, open-label,parallel-group study in Japanese adults with established coronary artery disease Reviewed

    Koyasu M, Ishii H, Watarai M, Takemoto K, Inden Y, Takeshita K, Amano T,Yoshikawa D, Matsubara T, Murohara T

    Clin Ther   Vol. 32 ( 9 ) page: 1610-7   2010

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  140. The difference in autonomic denervation and its effect on atrial fibrillation recurrence between the standard segmental and circumferential pulmonary vein isolation techniques. Reviewed

    Yamada T, Yoshida N, Murakami Y, Okada T, Yoshida Y, Muto M, Inden Y, Murohara T

    Europace   Vol. 11 ( 12 ) page: 1612-1619   2009.12

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  141. *Reactive oxidative metabolites are associated with atrial conduction disturbance in patients with atrial fibrillation. Reviewed

    Shimano M, Shibata R, Inden Y, Yoshida N, Uchikawa T, Tsuji Y, Murohara T

    Heart Rhythm   Vol. 6 ( 7 ) page: 935-940   2009.4

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  142. Vagal modification can also help prevent late recurrence of atrial fibrillation after segmental pulmonary vein isolation. Reviewed

    Yoshida N, Yamada T, Murakami Y, Okada T, Ninomiya Y, Toyama J, Yoshida Y, Tsuboi N, Muto M, Inden Y, Hirai M, Murohara T

    Circ J   Vol. 73 ( 4 ) page: 632-638   2008.12

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  143. Circulating homocysteine levels in patients with radiofrequency catheter ablation for atrial fibrillation. Europace. Reviewed

    Shimano M, Inden Y, Tsuji Y, Kamiya H, Uchikawa T, Shibata R, Murohara T

    Europace   Vol. 10 ( 8 ) page: 961-966   2008.8

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  144. Circulating adiponectin levels in patients with atrial fibrillation. Reviewed

    Shimano M, Shibata R, Tsuji Y, Kamiya H, Uchikawa T, Harata S, Muto M, Ouchi N, Inden Y, Murohara T

    Circ J   Vol. 72 ( 7 ) page: 1120-1124   2008.7

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  145. *Pioglitazone, a peroxisome proliferator-activated receptor-gamma activator, attenuates atrial fibrosis and atrial fibrillation promotion in rabbits with congestive heart failure.

    Shimano M, Tsuji Y, Inden Y, Kitamura K, Uchikawa T, Harata S, Nattel S, Murohara T

    Heart Rhythm   Vol. 5 ( 3 ) page: 451-459   2008.3

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  146. Electrophysiologic characteristics and outcome of segmental ostial superior vena cava isolation in patients with paroxysmal atrial fibrillation initiated by superior vena cava ectopy: comparison with pulmonary vein isolation. Reviewed

    Muto M, Yamada T, Murakami Y, Okada T, Okamoto M, Shimizu T, Toyama J,Yoshida Y, Tsuboi N, Ito T, Kondo T, Inden Y, Hirai M, Murohara T

    J Electrocardiol   Vol. 40 ( 4 ) page: 319-325   2007.10

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  147. Prevalence and severity of left atrial edema detected by electron beam tomography early after pulmonary vein ablation. Reviewed

    Okada T, Yamada T, Murakami Y, Yoshida N, Ninomiya Y, Shimizu T, Toyama J, Yoshida Y, Ito T, Tsuboi N, Kondo T, Inden Y, Hirai M, Murohara T

    J Am Coll Cardiol   Vol. 49 ( 13 ) page: 1436-1442   2007.4

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  148. Does RV lead positioning provide additional benefit to cardiac resynchronization therapy in patients with advanced heart failure? Reviewed

    Shimano M, Inden Y, Yoshida Y, Tsuji Y, Tsuboi N, Okada T, Yamada T, Murakami Y, Takada Y, Hirayama H, Murohara T

    Pacing Clin Electrophysiol   Vol. 29 ( 10 ) page: 1069-1074   2006

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  149. Sinoatrial node dysfunction and early unexpected death of mice with a defect of klotho gene expression. Reviewed

    Takeshita K, Fujimori T, Kurotaki Y, Honjo H, Tsujikawa H, Yasui K, Lee JK,Kamiya K, Kitaichi K, Yamamoto K, Ito M, Kondo T, Iino S, Inden Y, Hirai M,Murohara T, Kodama I, Nabeshima Y

    Circulation   Vol. 109 ( 14 ) page: 1776-17782   2004.4

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  150. Smoking cessation rapidly increases circulating progenitor cells in peripheral blood in chronic smokers Reviewed

    Kondo T, Hayashi M, Takeshita K, Numaguchi Y, Kobayashi K, Iino S, Inden Y, Murohara T

    Arterioscler Thromb Vasc Biol   Vol. 24   page: 1442-1447   2004

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  151. Diagnostic usefulness of postexercise systolic blood pressure response for detection of coronary artery disease in patients with echocardiographic left ventricular hypertrophy Reviewed

    Yamada K, Hirai M, Abe K, Ishihara H, Takeshita K, Takada Y, Mutoh M, Noda H, Shimizu A, Shibata Y, Yamada T, Kondo T, Yoshida Y, Inden Y, Murohara T

    Can J Cardiol   Vol. 20   page: 705-711   2004

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  152. *Ionic mechanisms of acquired QT prolongation and torsades de pointes in rabbits with chronic complete atrioventricular block. Reviewed

    Tsuji Y, Opthof T, Yasui K, Inden Y, Takemura H, Niwa N, Lu Z, Lee JK, Honjo H, Kamiya K, Kodama I

    Circulation   Vol. 106 ( 15 ) page: 2012-2018   2002.10

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  153. Repetitive atrial flutter as a complication of the left-sided simple maze procedure. Reviewed

    Usui A, Inden Y, Mizutani S, Takagi Y, Akita T, Ueda Y

    Ann Thorac Surg   Vol. 73 ( 5 ) page: 1457-1459   2002.5

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  154. Changes in repolarization properties with long-term cardiac memory modify dispersion of repolarization in patients with Wolff-Parkinson-White syndrome. Reviewed

    akada Y, Inden Y, Akahoshi M, Shibata Y, Shimizu A, Yoshida Y, Yamada T, Tsuboi N, Hirayama H, Ito T, Kondo T, Saito H, Hirai M

    J Cardiovasc Electrophysiol   Vol. 13 ( 4 ) page: 324-330   2002.4

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  155. *Prolongation of activation-recovery interval over a preexcited region before and after catheter ablation in patients with Wolff-Parkinson-White syndrome. Reviewed

    Inden Y, Hirai M, Takada Y, Shimizu A, Shimokata K, Yoshida Y, Akahoshi M,Kondo T, Saito H

    J Cardiovasc Electrophysiol   Vol. 12 ( 8 ) page: 933-945   2001.4

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  156. Antiarrhythmic efficacy of dipyridamole in treatment of reperfusion arrhythmias : evidence for cAMP-mediated triggered activity as a mechanism responsible for reperfusion arrhythmias. Reviewed

    Yoshida Y, Hirai M, Yamada T, Tsuji Y, Kondo T, Inden Y, Akahoshi M, MurakamiY, Tsuda M, Tsuboi N, Hirayama H, Okamoto M, Ito T, Saito H, Toyama J

    Circulation   Vol. 101 ( 6 ) page: 624-630   2000.2

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  157. Relationship between Joint National Committee-VI classification of hypertension and ambulatory blood pressure in patients with hypertension diagnosed by casual blood pressure. Reviewed

    Inden Y, Tsuda M, Hayashi H, Takezawa H, Iino S, Kondo T, Yoshida Y, Akahoshi M, Terasawa M, Itoh T, Saito H, Hirai M

    Clin Cardiol   Vol. 21 ( 11 ) page: 801-806   1998.11

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  158. Body-surfacedistribution of changes in activation-recovery intervals before and after catheter ablation in patients with Wolff-Parkinson-White syndrome: clinical evidence for ventricular 'electrical remodeling' with prolongation of action-potential duration over a preexcited area. Reviewed

    Akahoshi M, Hirai M, Inden Y, Sano H, Shimizu A, Kondo T, Makino M, Horiba M,Yoshida Y, Tsuboi N, Hirayama H, Ito T, Hayashi H, Saito H

    Circulation   Vol. 96 ( 5 ) page: 1566-1574   1997.9

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  159. Body surface distribution of abnormally low QRST areas in patients with Wolff-Parkinson-White syndrome. Evidence for continuation of repolarization abnormalities before and after catheter ablation. Reviewed

    Hirai M, Tsuboi N, Hayashi H, Ito M, Inden Y, Hirayama H, Ito T, Yanagawa T, Sano H, Kondo T, et al

    Circulation   Vol. 88 ( 6 ) page: 2674-2684   1993.12

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Presentations 6

  1. A Novel Combined Assessment of Left Ventricular Dyssynchrony and Contractility by Radial Strain Echocardiography Predicts Responders to Cardiac Resynchronization Therapy International conference

    第82回American Heart Association Scientific Sessions 

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    Event date: 2009.11

    Language:English   Presentation type:Oral presentation (general)  

  2. Bepridil Magnifies Left-to-Right Atrial Frequency Gradient in Chronic Atrial Fibrillation

    The 71st Annual Scientific Meeting of the Japanese Circulation Society 

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    Event date: 2007.3

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  3. Atrial Fibrillation is Associated with Collagen Type I Synthesis in Patients without Organic Heart Disease International conference

    Heart Rhythm Society 2006 

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    Event date: 2006.5

    Language:English   Presentation type:Oral presentation (general)  

  4. Paroxysmal Atrial Fibrillation Terminates by Pilsicainide through Attenuation of Left-to-Right Atrial Frequency Gradient

    The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society 

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    Event date: 2006.3

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  5. Novel ECG parameters during atrial fibrillation predict th possibility of conversion by the infusion of pilsicainide International conference

    Heart Rhythm Society 2005 

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    Event date: 2005.5

    Language:English   Presentation type:Oral presentation (general)  

  6. Atrial Fibrillation is Associated with Collagen Type I Synthesis in Patients without Organic Heart Disease

    The 69th Annual Scientific Meeting of the Japanese Circulation Society 

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    Event date: 2005.3

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

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Research Project for Joint Research, Competitive Funding, etc. 1

  1. PPARγアゴニストおよびMMP阻害薬による心筋線維化抑制作用と不整脈抑制作用

    2006

KAKENHI (Grants-in-Aid for Scientific Research) 6

  1. 頸動脈波の微小栓子シグナル信号解析を用いた、有効で安全な次世代不整脈治療法の確立

    Grant number:23K07549  2023.4 - 2027.3

    科学研究費助成事業  基盤研究(C)

    柳澤 哲, 因田 恭也

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    Authorship:Coinvestigator(s)  Grant type:Competitive

    本研究は、微小栓子を描出可能な専用の頸動脈ドップラー血流超音波装置を用いて、不整脈アブレーション治療における潜在的脳梗塞のリスクを評価することである。そして、新しい手技法や出力エネルギーの違い、アプローチ法、術中の抗凝固管理等様々な視点から塞栓リスクを評価し、より安全で有効な不整脈治療・予防法を確立することにある。さらに、検出された微小栓子と凝固機能活性化や高次脳機能への影響を評価する。
    本研究は、微小栓子を描出可能な専用の頸動脈ドップラー血流超音波装置を用いて、不整脈カテーテルアブレーション治療中における潜在的脳梗塞のリスクを評価することである。本装置は比較的装着の平易な、侵襲の少ないプローベを頸部に貼付することにより、ドップラー血流解析を連続的に行うことができ、微小栓子発生の頻度やその種類についても評価を行うことが可能である。
    今年度は、既に出力の違いによる微小栓子発生の違いについて、前向きの無作為比較研究を立案し、当院での生命倫理審査委員会の承認を得たのち、研究実施を開始して症例登録を続けている。この微小栓子の発生については、治療中の部位においても、発生頻度の違いが観察されており、その特徴的な傾向と誘因についてさらに解析を進めている。また汎用的に登録を続けているカテーテルアブレーション症例の評価研究についても、連続的にデータ解析を行っており、多種多様な不整脈アブレーションの手技とそのリスク・危険性についてデータを収集している。今年度までに、研究開始から40例以上のデータ収集を行うことができた。この内カテーテルデバイスの違いによる栓子発生の違いについて着目し、現在解析と検討を進めている途中である。また、この頸動脈エコー器機について、他施設共同での研究実施についても計画を立案し、現在多施設共同でのアブレーション中の微小栓子または微小空気発生の評価について研究計画を進めているところである。
    アブレーション中の出力の違いによる無作為化比較研究において、症例数の見積もり予定を見直し、研究実施期間と目標症例数の修正を行った。その他、後ろ向き解析においては症例数の蓄積が得られ、現在テーマごとに解析を進めている。
    今後も引き続き症例登録を続けて、できるだけ多くの症例登録を目指す。また得られた結果をもとに分析を開始していく予定である。

  2. 非可逆的電気穿孔法の出力設定最適化と心室性不整脈治療への応用に関する検討

    Grant number:22K08177  2022.4 - 2025.3

    科学研究費助成事業  基盤研究(C)

    因田 恭也, 辻 幸臣

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    Authorship:Principal investigator 

    Grant amount:\3900000 ( Direct Cost: \3000000 、 Indirect Cost:\900000 )

    カテーテルアブレーションにおける高周波に代わるエネルギー源として電界パルスを用いた非可逆的電気穿孔法が考案された。本法はその通電設定により心筋に特異的な障害を加えることが可能で、本法による心房細動治療の実験的検討が行われ、さらに臨床応用が始まろうとしている。しかし、これまでの報告では、電界パルスの幅、回数、頻度、電界などの条件は十分に検討されておらず、また心室性不整脈に対する治療効果は不明である。本研究の目的は、電界パルスを用いた非可逆的電気穿孔法の設定条件を心筋及び周囲組織の組織学的な検討を踏まえ検討し、さらに心室頻拍心室細動などの難治性不整脈に対する治療効果を実験的に検討することである。
    初めに遺伝子導入に用いるパルス電界発生装置を用いてウサギ心筋への影響を検討した。この装置の最大電圧は300Vであり、パルス幅は長く、回数も少ない設定であった。繰り返し300V通電を行うことにより永続的な房室ブロックを作成できた。
    独自に作成したパルス電界発生装置を用いて、ウサギ、豚の心筋への効果を検討した。ウサギ心筋にて、様々な出力、パルス幅、パルス間隔を試したところ、850V、パルス幅30μs、パルス間隔30μs 、総通電時間100msにて、2mm程度の病変の作成が可能であった。ウサギにおいて房室ブロック作成を試みた。心外膜側から一過性の完全房室ブロックを作成することが可能であったが、多くは一過性の房室ブロックであった。その後のPR間隔は元に戻っていたことより、刺激伝導系と心筋組織とでは、PFAに対するダメージ閾値が異なることが予想された。また複数回通電することによりブロックが完成されることが確かめられた。
    パルス幅を800μsと長くすると房室ブロック作成できず、30μでは房室ブロックを作成できた。表面には焼けどの様な所見も伴っていたものの、HE染色では正常組織と違いなく、TTC染色にて病巣を確認し、PFAによる障害であると判断した。
    豚心筋にて電圧を650Vから850Vまで変化させると、病変も拡大した。しかしながら、病変は浅く、心筋心外膜側からの通電では心筋中層や心内膜層に病変を作成することはできなかった。右室心筋に線状通電を試みたが、貫壁性の病変は作成されなかった。っ複数回の通電により、より深い病変を作成できることが確認された。
    独自に作成したパルス電界発生装置のトラブルが多く、高出力にて機器内での電流ショートが発生、その修理に時間を要するなど、なかなか実験が進まなかった。しかし、実際に心筋でPFAによる病変作成が確認されたことは意義がある。本来は様々な組織や、心臓内各所での効果の違いなども検討したいところであったものの、現状ではそこまで行えていない。
    独自に作成したパルス電界発生装置では高出力通電ができないため、電界発生装置の改良が必要である者の、容易ではない。現状で可能な出力にて、心筋内各所での通電効果の違い、血管や神経への影響、房室結節やプルキンエ線維への効果を検討する。またより深い病変作成のための通電方法の工夫を行う。

  3. 治療抵抗性致死的不整脈に対する定位放射線治療の研究

    Grant number:21K07725  2021.4 - 2026.3

    科学研究費助成事業  基盤研究(C)

    川村 麻里子, 因田 恭也, 駒田 智大

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    Authorship:Coinvestigator(s) 

    器質的心疾患に伴う心室頻拍(VT)はしばしば難治性である。国外を中心に、この難治性なVTに対する放射線を用いた非侵襲的アブレーション治療の臨床試験が行われ、短期的には良好な結果が報告されている。本研究では海外での研究成果を基盤に、国内の診療体制でも実現可能な方法へ変換し、高精度定位放射線治療によるアブレーション治療技術を開発するものである。本治療が本邦でも施行可能となることで、現在治療法がなく、突然死の恐怖と日々戦っている患者の希望となると確信している。
    致死的不整脈に対する定位放射線治療の特定臨床試験実施のために、プロトコルを作成し、院内の倫理審査を経て、2023年6月に正式にプロトコルが承認された。本試験ではまず、3名の患者に対する本治療の安全性を検討することとしている。特定臨床研究の実施に際しては、JRCTsにて公開(jRCTs042230030)し、臨床試験プロトコルについては英語論文化し、公開した。
    (Stereotactic radiotherapy for ventricular tachycardia: A study protocol. https://doi.org/10.12688/f1000research.138758.2)
    更に、11月に、2名の患者に対し、本治療を実施し、現在、経過観察中である。前年度、先行施設見学として、当初予定していたワシントン大学ではなく、チェコのオストラバ大学とスイスのCHUV大学へ施設見学し、協力要請を行ったことから、同施設に2名の患者の治療に際しては、協力を依頼し、治療計画作成時にZoomでのカンファレンスも実施した上で治療を行なった。
    当初予定したワシントン大学から見学先を変更した理由として、ワシントン大学で使用している照射装置と当院で使用している照射装置が異なることから、当院で採用している照射装置を用いて本治療の実施実績のあるオストラバ大学、CHUV大学へ協力を仰いだ。治療の実施については研究会でも報告しており、現在、論文化に向けて準備中である。現時点では大きな合併症もなく、順調である。
    R6年度中に臨床試験を開始する予定だったが、R5年度中に開始できた。
    特定臨床試験としてはあと1名の治療を実施し、1年間フォローを行う予定である。それらの結果を国内外で発表する予定である。

  4. Evaluation by Frequency Analysis of Surface Electrocardiogram and Rotor Mapping in Left Atrum

    Grant number:15K09076  2015.4 - 2018.3

    Yasuya Inden

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    Authorship:Principal investigator 

    Grant amount:\4680000 ( Direct Cost: \3600000 、 Indirect Cost:\1080000 )

    Dominant frequency (DF) of atrial fibrillation (AF) reflects atrial electrical activity. We retrospectively investigated 78 patients who underwent catheter ablation due to persistent AF. The high DF of lead aVL and V1 was a predictor of arrhythmia recurrence after persistent AF ablation.
    Electrical rotors may be targets in ablations for persistent atrial fibrillation. Unipolar electrograms in left atrium were recorded with using basket catheter, and we analyzed rotational activities by NavX. rotors were recognized in anterior and posterior LA. We performed PV isolation and delivered RF application to the rotors. AF terminated in some patients and more patients maintained sinus rhythm. Rotors could be able to be recognized by use of basket catheter and EnSite system in patients with persistent AF and may be the target of ablation in persistent AF next to PVI.

  5. Exploratory research of microscopic myocardial injury by irradiation using averaged electrocardiogram

    Grant number:26461883  2014.4 - 2018.3

    Tohru Okada

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    Authorship:Coinvestigator(s) 

    In this study, to explore myocardial damage due to irradiation, we use averaged electrocardiogram that can identify microscopic myocardial injury. Interventions other than the above were judged to deviate from regular medical practice, therefore this study was approved in our hospital as a prospective clinical trial considerably later than the original schedule. About 40% of the case arrival number (30 cases) was accumulated and analyzed as much as possible this time. No significant change was observed by irradiation with fQRS-d, RMS 40ms, LAS 40μV which are indicators of the averaged electrocardiogram. In E/e’ which is an index of diastolic cardiac function at echocardiogram, an upward trend was observed after 6 months of irradiation, although a statistically significant difference was not observed. This study will continue as an in-hospital clinical trial and accumulate cases and plan to reanalyze as soon as the number of cases is reached.

  6. Pioglitazone, a peroxisome proliferator-activated receptor-gamma activator, attenuates atrial fibrosis and atrial fibrillation-promotion

    2006.4 - 2008.3

    Grant-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research(C)

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    Authorship:Principal investigator 

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Teaching Experience (On-campus) 11

  1. 循環器内科

    2022

  2. 循環器内科選択講義

    2022

  3. 循環器

    2021

  4. 循環器内科

    2023

  5. 循環器内科選択講義

    2023

  6. 循環器内科ポリクリ実習

    2023

  7. 循環器内科ポリクリ実習

    2022

  8. 循環器

    2021

  9. 循環器ポリクリ

    2021

  10. 循環器

    2020

  11. 循環器

    2020

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