日本緩和医療学会

日本臨床細胞学会

日本臨床腫瘍学会

Chemoresistance to paclitaxel induces epithelial-mesenchymal transition and enhances metastatic potential for epithelial ovarian carcinoma cells. Reviewed

Kajiyama H, Shibata K, Terauchi M, Yamashita M, Ino K, Nawa A, Kikkawa F.

Int J Oncol   Vol. 31 ( 2 ) page： 277-83   2007.8

Involvement of aminopeptidase N in enhanced chemosensitivity to paclitaxel in ovarian carcinoma in vitro and in vivo. Reviewed

Yamashita M, Kajiyama H, Terauchi M, Shibata K, Ino K, Nawa A, Mizutani S, Kikkawa F

Int J Cancer.   Vol. 120 ( 10 ) page： 2243-50   2007.5

Expression of Twist increases the risk for recurrence and for poor survival in epithelial ovarian carcinoma patients. Reviewed

Hosono S, Kajiyama H, Terauchi M, Shibata K, Ino K, Nawa A, Kikkawa F

Br J Cancer.   Vol. 96 ( 2 ) page： 314-20   2007.1

Involvement of DPPIV/CD26 in epithelial morphology and suppressed invasive ability in ovarian carcinoma cells Reviewed

Kajiyama H, Shibata K, Terauchi M, Ino K, Nawa A, Kikkawa F.

Ann N Y Acad Sci   Vol. 1086   page： 233-40   2006.11

Anti-progressive effect of neutral endopeptidase 24.11 (NEP/CD10) on cervical carcinoma in vitro and in vivo. Reviewed

Terauchi M, Kajiyama H, Shibata K, Ino K, Mizutani S, Kikkawa F.

Oncology   Vol. 69 ( 1 ) page： 52-62   2005.8

Neutral endopeptidase 24.11/CD10 suppresses progressive potential in ovarian carcinoma in vitro and in vivo. Reviewed

Kajiyama H, Shibata K, Terauchi M, Morita T, Ino K, Mizutani S, Kikkawa F.

Clin Cancer Res.   Vol. 11 ( 5 ) page： 1798-808   2005.3

*Involvement of SDF-1alpha/CXCR4 axis in the enhanced peritoneal metastasis of epithelial ovarian carcinoma. Reviewed

Kajiyama H, Shibata K, Terauchi M, Ino K, Nawa A, Kikkawa F.

Int J Cancer   Vol. 122 ( 1 ) page： 91-9   2008.1

Dipeptidyl peptidase IV overexpression induces up-regulation of E-cadherin and tissue inhibitors of matrix metalloproteinases, resulting in decreased invasive potential in ovarian carcinoma cells. Reviewed

Kajiyama H, Kikkawa F, Khin E, Shibata K, Ino K, Mizutani S.

Cancer Res.   Vol. 63 ( 9 ) page： 2278-83   2003.5

*Prolonged survival and decreased invasive activity attributable to dipeptidyl peptidase IV overexpression in ovarian carcinoma. Reviewed

Kajiyama H, Kikkawa F, Suzuki T, Shibata K, Ino K, Mizutani S.

Cancer Res.   Vol. 62 ( 10 ) page： 2753-7   2002.5

Fertility-sparing surgery in patients with clear-cell carcinoma of the ovary: is it possible? Reviewed

Kajiyama H, Shibata K, Mizuno M, Hosono S, Kawai M, Nagasaka T, Kikkawa F.

Hum Reprod.   Vol. 26 ( 12 ) page： 3297-302   2101.11

Aberrant inflammation in rat pregnancy leads to cardiometabolic alterations in their offspring and intrauterine growth restriction in the F2 generation.

Ushida T, Cotechini T, Protopapas N, Atallah A, Collyer C, Toews AJ, Macdonald-Goodfellow SK, Tse MY, Winn LM, Pang SC, Adams MA, Othman M, Kotani T, Kajiyama H, Graham CH

Journal of developmental origins of health and disease     page： 1 - 13   2022.5

Aberrant Activation of Cell-Cycle-Related Kinases and the Potential Therapeutic Impact of PLK1 or CHEK1 Inhibition in Uterine Leiomyosarcoma.

Yoshida K, Yokoi A, Yamamoto T, Hayashi Y, Nakayama J, Yokoi T, Yoshida H, Kato T, Kajiyama H, Yamamoto Y

Clinical cancer research : an official journal of the American Association for Cancer Research   Vol. 28 ( 10 ) page： 2147 - 2159   2022.5

Intrauterine exposure to hypertensive disorders of pregnancy and postnatal growth in extremely and very preterm infants.

Ushida T, Kotani T, Nakatochi M, Kobayashi Y, Nakamura N, Imai K, Iitani Y, Nakano-Kobayashi T, Hayakawa M, Kajiyama H, Neonatal Research Network of Japan.

Pregnancy hypertension   Vol. 28   page： 174 - 179   2022.5

Reassessing the duration of each stage of labor and their relation to postpartum hemorrhage in the current Japanese population

Ushida Takafumi, Matsuo Seiko, Nakamura Noriyuki, Iitani Yukako, Imai Kenji, Nakano-Kobayashi Tomoko, Yoshida Shigeru, Yamashita Mamoru, Kajiyama Hiroaki, Kotani Tomomi

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH     2022.5

Cytotoxicity of plasma-irradiated lactate solution produced under atmospheric airtight conditions and generation of the methyl amino group

Ito Daiki, Iwata Naoyuki, Ishikawa Kenji, Nakamura Kae, Hashizume Hiroshi, Miron Camelia, Tanaka Hiromasa, Kajiyama Hiroaki, Toyokuni Shinya, Mizuno Masaaki, Hori Masaru

APPLIED PHYSICS EXPRESS   Vol. 15 ( 5 )   2022.5

Is cystectomy an option as conservative surgery for young patients with borderline ovarian tumor? A multi-institutional retrospective study

Ikeda Yoshiki, Yoshihara Masato, Yoshikawa Nobuhisa, Tamauchi Satoshi, Yokoi Akira, Nishino Kimihiro, Niimi Kaoru, Kajiyama Hiroaki

INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS   Vol. 157 ( 2 ) page： 437 - 443   2022.5

Peritoneal restoration by repurposing vitamin D inhibits ovarian cancer dissemination via blockade of the TGF-β1/thrombospondin-1 axis.

Kitami K, Yoshihara M, Tamauchi S, Sugiyama M, Koya Y, Yamakita Y, Fujimoto H, Iyoshi S, Uno K, Mogi K, Ikeda Y, Yokoi A, Yoshikawa N, Nishino K, Niimi K, Nawa A, Enomoto A, Kajiyama H

Matrix biology : journal of the International Society for Matrix Biology   Vol. 109   page： 70 - 90   2022.5

Machine learning prediction models for postpartum depression: A multicenter study in Japan

Matsuo Seiko, Ushida Takafumi, Emoto Ryo, Moriyama Yoshinori, Iitani Yukako, Nakamura Noriyuki, Imai Kenji, Nakano-Kobayashi Tomoko, Yoshida Shigeru, Yamashita Mamoru, Matsui Shigeyuki, Kajiyama Hiroaki, Kotani Tomomi

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH     2022.4

Assessment of placental abruption with diffusion-weighted imaging

Mizutani Teruyuki, Kotani Tomomi, Kato Noriko, Imai Kenji, Ushida Takafumi, Nakano-Kobayashi Tomoko, Kinoshita Yoshimi, Ito Masato, Kinoshita Fumie, Yamamuro Osamu, Kajiyama Hiroaki

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH   Vol. 48 ( 4 ) page： 930 - 937   2022.4

Metastatic Voyage of Ovarian Cancer Cells in Ascites with the Assistance of Various Cellular Components

Uno Kaname, Iyoshi Shohei, Yoshihara Masato, Kitami Kazuhisa, Mogi Kazumasa, Fujimoto Hiroki, Sugiyama Mai, Koya Yoshihiro, Yamakita Yoshihiko, Nawa Akihiro, Kanayama Tomohiro, Tomita Hiroyuki, Enomoto Atsushi, Kajiyama Hiroaki

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES   Vol. 23 ( 8 )   2022.4

Crosstalk between foetal vasoactive peptide hormones and placental aminopeptidases regulates placental blood flow: Its significance in preeclampsia

Yoshihara Masato, Mizutani Shigehiko, Matsumoto Kunio, Kato Yukio, Masuo Yusuke, Tano Sho, Mizutani Hidesuke, Kotani Tomomi, Mizutani Eita, Shibata Kiyosumi, Kajiyama Hiroaki

PLACENTA   Vol. 121   page： 32 - 39   2022.4

Effectiveness of NLRP3 Inhibitor as a Non-Hormonal Treatment for ovarian endometriosis

Murakami Mayuko, Osuka Satoko, Muraoka Ayako, Hayashi Shotaro, Bayasula, Kasahara Yukiyo, Sonehara Reina, Hariyama Yumi, Shinjo Kanako, Tanaka Hideaki, Miyake Natsuki, Yoshita Sayako, Nakanishi Natsuki, Nakamura Tomoko, Goto Maki, Kajiyama Hiroaki

REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY   Vol. 20 ( 1 ) page： 58   2022.3

Annual Body Mass Index Gain and Risk of Gestational Diabetes Mellitus in a Subsequent Pregnancy

Tano Sho, Kotani Tomomi, Ushida Takafumi, Yoshihara Masato, Imai Kenji, Nakano-Kobayashi Tomoko, Moriyama Yoshinori, Iitani Yukako, Kinoshita Fumie, Yoshida Shigeru, Yamashita Mamoru, Kishigami Yasuyuki, Oguchi Hidenori, Kajiyama Hiroaki

FRONTIERS IN ENDOCRINOLOGY   Vol. 13   page： 815390   2022.3

Increased Risk of Thyroid Dysfunction by PD-1 and CTLA-4 Blockade in Patients Without Thyroid Autoantibodies at Baseline

Iwama Shintaro, Kobayashi Tomoko, Yasuda Yoshinori, Okuji Takayuki, Ito Masaaki, Ando Masahiko, Zhou Xin, Yamagami Ayana, Onoue Takeshi, Kawaguchi Yohei, Miyata Takashi, Sugiyama Mariko, Takagi Hiroshi, Hagiwara Daisuke, Suga Hidetaka, Banno Ryoichi, Hase Tetsunari, Morise Masahiro, Wakahara Keiko, Yokota Kenji, Kato Masashi, Nishio Naoki, Tanaka Chie, Miyata Kazushi, Ogura Atsushi, Ito Takanori, Sawada Tsunaki, Shimokata Tomoya, Niimi Kaoru, Ohka Fumiharu, Ishigami Masatoshi, Gotoh Momokazu, Hashimoto Naozumi, Saito Ryuta, Kiyoi Hitoshi, Kajiyama Hiroaki, Ando Yuichi, Hibi Hideharu, Sone Michihiko, Akiyama Masashi, Kodera Yasuhiro, Arima Hiroshi

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM   Vol. 107 ( 4 ) page： E1620 - E1630   2022.3

Is adjuvant chemotherapy necessary for young women with early-stage epithelial ovarian cancer who have undergone fertility-sparing surgery?: a multicenter retrospective analysis

Ikeda Yoshiki, Yoshihara Masato, Yoshikawa Nobuhisa, Yokoi Akira, Tamauchi Satoshi, Nishino Kimihiro, Niimi Kaoru, Kajiyama Hiroaki

BMC WOMENS HEALTH   Vol. 22 ( 1 ) page： 80   2022.3

Significance of platinum distribution to predict platinum resistance in ovarian cancer after platinum treatment in neoadjuvant chemotherapy

Uno Kaname, Yoshikawa Nobuhisa, Tazaki Akira, Ohnuma Shoko, Kitami Kazuhisa, Iyoshi Shohei, Mogi Kazumasa, Yoshihara Masato, Koya Yoshihiro, Sugiyama Mai, Tamauchi Satoshi, Ikeda Yoshiki, Yokoi Akira, Kikkawa Fumitaka, Kato Masashi, Kajiyama Hiroaki

SCIENTIFIC REPORTS   Vol. 12 ( 1 ) page： 4513   2022.3

Functional Lactotrophs in Induced Adenohypophysis Differentiated From Human iPS Cells

Miyake Natsuki, Nagai Takashi, Suga Hidetaka, Osuka Satoko, Kasai Takatoshi, Sakakibara Mayu, Soen Mika, Ozaki Hajime, Miwata Tsutomu, Asano Tomoyoshi, Kano Mayuko, Muraoka Ayako, Nakanishi Natsuki, Nakamura Tomoko, Goto Maki, Yasuda Yoshinori, Kawaguchi Yohei, Miyata Takashi, Kobayashi Tomoko, Sugiyama Mariko, Onoue Takeshi, Hagiwara Daisuke, Iwama Shintaro, Iwase Akira, Inoshita Naoko, Arima Hiroshi, Kajiyama Hiroaki

ENDOCRINOLOGY   Vol. 163 ( 3 )   2022.3

Adjuvant taxane plus platinum chemotherapy for stage I ovarian clear cell carcinoma with complete surgical staging: are more than three cycles necessary?

Ukai Mayu, Suzuki Shiro, Yoshihara Masato, Yokoi Akira, Yoshikawa Nobuhisa, Kajiyama Hiroaki, Kikkawa Fumitaka

INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY   Vol. 27 ( 3 ) page： 609 - 618   2022.3

Survival and reproductive outcomes after fertility-sparing surgery performed for borderline epithelial ovarian tumor in Japanese adolescents and young adults: Results of a retrospective nationwide study

Kuji Shiho, Harada Miyuki, Yoshioka Norihito, Kajiyama Hiroaki, Satoh Toyomi, Mikami Mikio, Shozu Makio, Enomoto Takayuki, Osuga Yutaka, Suzuki Nao

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH   Vol. 48 ( 3 ) page： 806 - 816   2022.3

Tamoxifen Activates Dormant Primordial Follicles in Mouse Ovaries

Wei Wei, Komatsu Kouji, Osuka Satoko, Murase Tomohiko, Bayasula Bayasula, Nakanishi Natsuki, Nakamura Tomoko, Goto Maki, Iwase Akira, Masubuchi Satoru, Kajiyama Hiroaki

REPRODUCTIVE SCIENCES     2022.2

Survival benefits of retroperitoneal lymphadenectomy for optimally-resected advanced ovarian high-grade serous carcinoma: a multi-institutional retrospective study.

Ikeda Y, Yoshihara M, Tamauchi S, Yokoi A, Yoshikawa N, Kajiyama H

Journal of gynecologic oncology     2022.2

Adipose-mesothelial crosstalk regulates peritoneal tumor microenvironment and accelerates metastasis of ovarian cancer

Mogi Kazumasa, Yoshihara Masato, Uno Kaname, Iyoshi Shohei, Kitami Kazuhisa, Sugiyama Mai, Koya Yoshihiro, Tamauchi Satoshi, Yokoi Akira, Yoshikawa Nobuhisa, Nawa Akihiro, Kajiyama Hiroaki

CANCER SCIENCE   Vol. 113   page： 735 - 735   2022.2

Prognostic impact of extracellular miRNAs in patients with high-grade serous ovarian carcinoma

Yoshida Kosuke, Yokoi Akira, Matsuzaki Juntaro, Kato Tomoyasu, Ochiya Takahiro, Kajiyama Hiroaki, Yamamoto Yusuke

CANCER SCIENCE   Vol. 113   page： 1788 - 1788   2022.2

Pre-pregnancy sleep duration and postpartum depression: a multicenter study in Japan

Matsuo Seiko, Ushida Takafumi, Iitani Yukako, Imai Kenji, Nakano-Kobayashi Tomoko, Moriyama Yoshinori, Yoshida Shigeru, Yamashita Mamoru, Kajiyama Hiroaki, Kotani Tomomi

ARCHIVES OF WOMENS MENTAL HEALTH   Vol. 25 ( 1 ) page： 181 - 189   2022.2

Notch-dependent intra-tumoral heterogeneity mediates cell-fate dynamics and development of peritoneal dissemination

Yoshihara Masato, Sugiyama Mai, Koya Yoshihiro, Iyoshi Shohei, Kitami Kazuhisa, Uno Kaname, Mogi Kazumasa, Nawa Akihiro, Kajiyama Hiroaki

CANCER SCIENCE   Vol. 113   page： 1405 - 1405   2022.2

Notch signaling contributes to drug resistance acquisition through metabolic alteration in advanced ovarian cancer

Sugiyama Mai, Yoshihara Masato, Koya Yoshihiro, Kitami Kazuhisa, Uno Kaname, Iyoshi Shohei, Mogi Kazumasa, Yokoi Akira, Nawa Akihiro, Kajiyama Hiroaki

CANCER SCIENCE   Vol. 113   page： 1280 - 1280   2022.2

NGFR contributes the malignancy of ovarian carcinoma cells

Koya Yoshihiro, Sugiyama Mai, Yoshihara Masato, Kitami Kazuhisa, Uno Kaname, Mogi Kazumasa, Iyoshi Shohei, Nawa Akihiro, Kajiyama Hiroaki

CANCER SCIENCE   Vol. 113   page： 1033 - 1033   2022.2

Frequency of homologous recombination deficiency in high-grade serous ovarian cancer in Japan; JGOG3025-TR2 study

Matsumura Noriomi, Takamatsu Shiro, Yoshihara Kosuke, Baba Tsukasa, Shimada Muneaki, Yoshida Hiroshi, Okamoto Aikou, Kajiyama Hiroaki, Oda Katsutoshi, Enomoto Takayuki

CANCER SCIENCE   Vol. 113   page： 827 - 827   2022.2

Discovering novel therapeutic agents for uterine leiomyosarcoma

Nagao Yukari, Yokoi Akira, Yoshida Kosuke, Watanabe Eri, Yoshihara Masato, Tamauchi Satoshi, Yoshikawa Nobuhisa, Yamamoto Yusuke, Kato Tomoyasu, Kajiyama Hiroaki

CANCER SCIENCE   Vol. 113   page： 1181 - 1181   2022.2

Chemical library-based drug repositioning strategy for choriocarcinoma therapy

Watanabe Eri, Yokoi Akira, Yoshida Kosuke, Yamamoto Yusuke, Nishino Kimihiro, Niimi Kaoru, Kajiyama Hiroaki

CANCER SCIENCE   Vol. 113   page： 1501 - 1501   2022.2

Anti-tumor capacity of specific contents in small extracellular vesicles derived from ADSCs in ovarian cancer

Yokoi Akira, Yoshida Kosuke, Uno Kaname, Kajiyama Hiroaki

CANCER SCIENCE   Vol. 113   page： 1408 - 1408   2022.2

Vitamin D inhibits mesothelial-mesenchymal-transition accelerating peritoneal dissemination in ovarian cancer via THBS1

Kitami Kazuhisa, Yoshihara Masato, Sugiyama Mai, Koya Yoshihiro, Yamakita Yoshihiko, Iyoshi Shohei, Uno Kaname, Mogi Kazumasa, Tamauchi Satoshi, Yokoi Akira, Yoshikawa Nobuhisa, Nishino Kimihiro, Niimi Kaoru, Nawa Akihiro, Kajiyama Hiroaki

CANCER SCIENCE   Vol. 113   page： 729 - 729   2022.2

Enhancement of ethanol production and cell growth in budding yeast by direct irradiation of low-temperature plasma

Tanaka Hiromasa, Matsumura Shogo, Ishikawa Kenji, Hashizume Hiroshi, Ito Masafumi, Nakamura Kae, Kajiyama Hiroaki, Kikkawa Fumitaka, Ito Mikako, Ohno Kinji, Okazaki Yasumasa, Toyokuni Shinya, Mizuno Masaaki, Hori Masaru

JAPANESE JOURNAL OF APPLIED PHYSICS   Vol. 61 ( SA )   2022.1

Cell surface membrane lysosome-associated membrane glycoprotein 2 promotes cell adhesion via abundant N-glycans in choriocarcinoma

Nishino Kimihiro, Nishiko Yuki, Shibata Mayu, Oda Yukari, Watanabe Eri, Niimi Kaoru, Yamamoto Eiko, Kajiyama Hiroaki

PLACENTA   Vol. 117   page： 109 - 117   2022.1

Placental Leucine Aminopeptidase as a Potential Specific Urine Biomarker for Invasive Ovarian Cancer

Matsukawa Tetsuya, Mizutani Shigehiko, Matsumoto Kunio, Kato Yukio, Yoshihara Masato, Kajiyama Hiroaki, Shibata Kiyosumi

JOURNAL OF CLINICAL MEDICINE   Vol. 11 ( 1 )   2022.1

Laparoscopic pelvic surgery after reconstructive surgery with vertical rectus abdominis muscle flap: A case report.

Nishino K, Ikeda Y, Kitami K, Niimi K, Kajiyama H

International journal of surgery case reports   Vol. 90   page： 106706   2022.1

Clinical practice guideline for the treatment of malignant ascites: section summary in Clinical Practice Guideline for peritoneal dissemination (2021)

Matsusaki Keisuke, Aridome Kuniaki, Emoto Shigenobu, Kajiyama Hiroaki, Takagaki Nobumasa, Takahashi Takao, Tsubamoto Hiroshi, Nagao Shoji, Watanabe Akihiro, Shimada Hideaki, Kitayama Joji

INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY   Vol. 27 ( 1 ) page： 1 - 6   2022.1

Impact of perioperative use of GnRH agonist or dienogest on ovarian reserve after cystectomy for endometriomas: a randomized controlled trial

Muraoka Ayako, Osuka Satoko, Yabuki Atsushi, Bayasula, Yoshihara Masato, Tanaka Hideaki, Sonehara Reina, Miyake Natsuki, Murakami Mayuko, Yoshita Sayako, Nakanishi Natsuki, Nakamura Tomoko, Goto Maki, Iwase Akira, Kajiyama Hiroaki

REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY   Vol. 19 ( 1 ) page： 179   2021.12

Clinical effects of cervical conization with positive margins in cervical cancer

Nagao Yukari, Yokoi Akira, Yoshida Kosuke, Sumi Masanori, Yoshihara Masato, Tamauchi Satoshi, Ikeda Yoshiki, Yoshikawa Nobuhisa, Nishino Kimihiro, Niimi Kaoru, Kajiyama Hiroaki

SCIENTIFIC REPORTS   Vol. 11 ( 1 ) page： 23288   2021.12

Pro-tumoral behavior of omental adipocyte-derived fibroblasts in tumor microenvironment at the metastatic site of ovarian cancer

Iyoshi Shohei, Yoshihara Masato, Nakamura Kae, Sugiyama Mai, Koya Yoshihiro, Kitami Kazuhisa, Uno Kaname, Mogi Kazumasa, Tano Sho, Tomita Hiroyuki, Kajiwara Keiji, Taki Masayasu, Yamaguchi Shigehiro, Nawa Akihiro, Kajiyama Hiroaki

INTERNATIONAL JOURNAL OF CANCER   Vol. 149 ( 11 ) page： 1961 - 1972   2021.12

Extracellular microRNA profiling for prognostic prediction in patients with high-grade serous ovarian carcinoma

Yoshida Kosuke, Yokoi Akira, Matsuzaki Juntaro, Kato Tomoyasu, Ochiya Takahiro, Kajiyama Hiroaki, Yamamoto Yusuke

CANCER SCIENCE   Vol. 112 ( 12 ) page： 4977 - 4986   2021.12

Recent Insights into Human Endometrial Peptidases in Blastocyst Implantation via Shedding of Microvesicles

Yoshihara Masato, Mizutani Shigehiko, Kato Yukio, Matsumoto Kunio, Mizutani Eita, Mizutani Hidesuke, Fujimoto Hiroki, Osuka Satoko, Kajiyama Hiroaki

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES   Vol. 22 ( 24 )   2021.12

Prevalence and risk factors of labor-onset hypertension: A multicenter study in Japan

Ushida Takafumi, Kotani Tomomi, Imai Kenji, Nakano-Kobayashi Tomoko, Iitani Yukako, Nakamura Noriyuki, Moriyama Yoshinori, Yoshida Shigeru, Yamashita Mamoru, Kajiyama Hiroaki

PREGNANCY HYPERTENSION-AN INTERNATIONAL JOURNAL OF WOMENS CARDIOVASCULAR HEALTH   Vol. 26   page： 48 - 53   2021.12

Long-term post-recurrence survival outcomes in young women receiving fertility-sparing surgery for epithelial ovarian cancer

Shigeyama Munehisa, Yoshihara Masato, Kitami Kazuhisa, Mogi Kazumasa, Uno Kaname, Iyoshi Shohei, Tano Sho, Yoshikawa Nobuhisa, Kajiyama Hiroaki

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY   Vol. 267   page： 221 - 225   2021.12

Hypertensive disorders of pregnancy and alterations in brain metabolites in preterm infants: A multi-voxel proton MR spectroscopy study

Katsuki Satoru, Ushida Takafumi, Kidokoro Hiroyuki, Nakamura Noriyuki, Iitani Yukako, Fuma Kazuya, Imai Kenji, Nakano-Kobayashi Tomoko, Sato Yoshiaki, Hayakawa Masahiro, Natsume Jun, Kajiyama Hiroaki, Kotani Tomomi

EARLY HUMAN DEVELOPMENT   Vol. 163   page： 105479   2021.12

Annual body mass index gain and risk of hypertensive disorders of pregnancy in a subsequent pregnancy

Tano Sho, Kotani Tomomi, Ushida Takafumi, Yoshihara Masato, Imai Kenji, Nakano-Kobayashi Tomoko, Moriyama Yoshinori, Iitani Yukako, Kinoshita Fumie, Yoshida Shigeru, Yamashita Mamoru, Kishigami Yasuyuki, Oguchi Hidenori, Kajiyama Hiroaki

SCIENTIFIC REPORTS   Vol. 11 ( 1 ) page： 22519   2021.11

Achievement of live birth after overcoming two gynecological malignancies treated with radical trachelectomy and medroxyprogesterone acetate therapy

Tamauchi Satoshi, Moriyama Yoshinori, Suzuki Shiro, Ikeda Yoshiki, Yoshikawa Nobuhisa, Kajiyama Hiroaki

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH   Vol. 47 ( 11 ) page： 4101 - 4105   2021.11

Manual removal of the placenta and postpartum hemorrhage: A multicenter retrospective study

Fujita Kei, Ushida Takafumi, Imai Kenji, Nakano-Kobayashi Tomoko, Iitani Yukako, Matsuo Seiko, Yoshida Shigeru, Yamashita Mamoru, Kajiyama Hiroaki, Kotani Tomomi

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH   Vol. 47 ( 11 ) page： 3867 - 3874   2021.11

Upregulation of ENDOU in cytotrophoblasts from placenta complicated with preeclampsia and fetal growth restriction

Nomoto Masataka, Kotani Tomomi, Miki Rika, Ushida Takafumi, Imai Kenji, Iitani Yukako, Tano Sho, Wang Jingwen, Moriyama Yoshinori, Kobayashi Tomoko, Mimura Nobuko, Iriyama Takayuki, Kikkawa Fumitaka, Kajiyama Hiroaki

JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION   Vol. 69 ( 3 ) page： 280 - 285   2021.11

Heat Shock Protein 105 as an Immunotherapeutic Target for Patients With Cervical Cancer

Nosaka Kazuto, Suzuki Shiro, Yoshikawa Toshiaki, Shimomura Manami, Kitami Kazuhisa, Yoshida Kosuke, Yoshihara Masato, Kikkawa Fumitaka, Nakatsura Tetsuya, Kajiyama Hiroaki

ANTICANCER RESEARCH   Vol. 41 ( 10 ) page： 4741 - 4751   2021.10

Plasma-activated Ringer's lactate solution inhibits the cellular respiratory system in HeLa cells

Tanaka Hiromasa, Maeda Shogo, Nakamura Kae, Hashizume Hiroshi, Ishikawa Kenji, Ito Mikako, Ohno Kinji, Mizuno Masaaki, Motooka Yashiro, Okazaki Yasumasa, Toyokuni Shinya, Kajiyama Hiroaki, Kikkawa Fumitaka, Hori Masaru

PLASMA PROCESSES AND POLYMERS   Vol. 18 ( 10 )   2021.10

Low temperature plasma irradiation products of sodium lactate solution that induce cell death on U251SP glioblastoma cells were identified

Tanaka Hiromasa, Hosoi Yugo, Ishikawa Kenji, Yoshitake Jun, Shibata Takahiro, Uchida Koji, Hashizume Hiroshi, Mizuno Masaaki, Okazaki Yasumasa, Toyokuni Shinya, Nakamura Kae, Kajiyama Hiroaki, Kikkawa Fumitaka, Hori Masaru

SCIENTIFIC REPORTS   Vol. 11 ( 1 ) page： 18488   2021.9

Short tandem repeat analysis to identify the causative pregnancy of high-risk gestational trophoblastic neoplasia: Molar versus nonmolar pregnancy and its relation to the outcome

Nishino Kimihiro, Yamamoto Eiko, Oda Yukari, Watanabe Eri, Niimi Kaoru, Yamamoto Toshimichi, Kajiyama Hiroaki

PLACENTA   Vol. 112   page： 28 - 35   2021.9

Current Issues within the Perinatal Mental Health Care System in Aichi Prefecture, Japan: A Cross-Sectional Questionnaire Survey

Fujita Kei, Kotani Tomomi, Moriyama Yoshinori, Ushida Takafumi, Imai Kenji, Kobayashi-Nakano Tomoko, Kato Noriko, Kano Takeo, Kikkawa Fumitaka, Kajiyama Hiroaki

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH   Vol. 18 ( 17 )   2021.9

Prenatal Molecular Hydrogen Administration Ameliorates Several Findings in Nitrofen-Induced Congenital Diaphragmatic Hernia

Miura Mayo, Imai Kenji, Tsuda Hiroyuki, Miki Rika, Tano Sho, Ito Yumiko, Hirako-Takamura Shima, Moriyama Yoshinori, Ushida Takafumi, Iitani Yukako, Nakano-Kobayashi Tomoko, Toyokuni Shinya, Kajiyama Hiroaki, Kotani Tomomi

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES   Vol. 22 ( 17 )   2021.9

Impact of incomplete surgery and adjuvant chemotherapy for the intraoperative rupture of capsulated stage I epithelial ovarian cancer: a multi-institutional study with an in-depth subgroup analysis

Yoshihara Masato, Tamauchi Satoshi, Iyoshi Shohei, Kitami Kazuhisa, Uno Kaname, Mogi Kazumasa, Kajiyama Hiroaki

JOURNAL OF GYNECOLOGIC ONCOLOGY   Vol. 32 ( 5 ) page： e66   2021.9

Frequency of homologous recombination associated gene mutations in Japanese patients with ovarian cancer

Yoshihara Kosuke, Baba Tsukasa, Shimada Mueaki, Yoshida Hiroshi, Okamoto Aikou, Kajiyama Hiroaki, Kagimura Tatsuo, Oda Katsutoshi, Sugiyama Toru, Enomoto Takayuki

GYNECOLOGIC ONCOLOGY   Vol. 162   page： S163 - S164   2021.8

Impact of maternal hypertensive disorders of pregnancy on brain volumes at term-equivalent age in preterm infants: A voxel-based morphometry study

Ushida Takafumi, Kidokoro Hiroyuki, Nakamura Noriyuki, Katsuki Satoru, Imai Kenji, Nakano-Kobayashi Tomoko, Moriyama Yoshinori, Sato Yoshiaki, Hayakawa Masahiro, Natsume Jun, Kajiyama Hiroaki, Kotani Tomomi

PREGNANCY HYPERTENSION-AN INTERNATIONAL JOURNAL OF WOMENS CARDIOVASCULAR HEALTH   Vol. 25   page： 143 - 149   2021.8

A large-scale multi-institutional study evaluating prognostic aspects of positive ascites cytology and effects of therapeutic interventions in epithelial ovarian cancer

Yoshihara Masato, Emoto Ryo, Kitami Kazuhisa, Iyoshi Shohei, Uno Kaname, Mogi Kazumasa, Tano Sho, Yoshikawa Nobuhisa, Matsui Shigeyuki, Kajiyama Hiroaki

SCIENTIFIC REPORTS   Vol. 11 ( 1 ) page： 15154   2021.7

Primate-specific POTE-actin gene could play a role in human folliculogenesis by controlling the proliferation of granulosa cells

Kasahara Yukiyo, Osuka Satoko, Takasaki Nobuyoshi, Bayasula, Koya Yoshihiro, Nakanishi Natsuki, Murase Tomohiko, Nakamura Tomoko, Goto Maki, Iwase Akira, Kajiyama Hiroaki

CELL DEATH DISCOVERY   Vol. 7 ( 1 ) page： 186   2021.7

Core 2 beta 1,6-N-acetylglucosaminyltransferases accelerate the escape of choriocarcinoma from natural killer cell immunity

Nakamura Kenichi, Niimi Kaoru, Yamamoto Eiko, Ikeda Yoshiki, Nishino Kimihiro, Suzuki Shiro, Kajiyama Hiroaki, Kikkawa Fumitaka

BIOCHEMISTRY AND BIOPHYSICS REPORTS   Vol. 26   page： 100951   2021.7

Reduced response to controlled ovarian stimulation after radical trachelectomy: A pitfall of fertility-sparing surgery for cervical cancer

Tamauchi Satoshi, Kajiyama Hiroaki, Osuka Satoko, Moriyama Yoshinori, Yoshihara Masato, Kikkawa Fumitaka

INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS   Vol. 154 ( 1 ) page： 162 - 168   2021.7

Lysosomal nitric oxide determines transition from autophagy to ferroptosis after exposure to plasma-activated Ringer's lactate

Jiang Li, Zheng Hao, Lyu Qinying, Hayashi Shotaro, Sato Kotaro, Sekido Yoshitaka, Nakamura Kae, Tanaka Hiromasa, Ishikawa Kenji, Kajiyama Hiroaki, Mizuno Masaaki, Hori Masaru, Toyokuni Shinya

REDOX BIOLOGY   Vol. 43   page： 101989   2021.7

Next-generation genome sequencing of a matched normal-tumor pair from a patient with intractable gestational choriocarcinoma: A case report

Niimi Kaoru, Yamamoto Eiko, Morita Sachi, Morikawa Maki, Hattori Hikaru, Hatakeyama Miki, Morita Mami, Nishino Kimihiro, Oda Yukari, Watanabe Eri, Yamamoto Toshimichi, Kajiyama Hiroaki, Kikkawa Fumitaka

MOLECULAR AND CLINICAL ONCOLOGY   Vol. 15 ( 1 ) page： 143   2021.7

Metabolome analysis reveals a diversity of cancer tissues in advanced epithelial ovarian cancer

Yoshida Kosuke, Yoshikawa Nobuhisa, Kitami Kazuhisa, Tamauchi Satoshi, Ikeda Yoshiki, Yokoi Akira, Nishino Kimihiro, Niimi Kaoru, Kajiyama Hiroaki

CANCER CELL INTERNATIONAL   Vol. 21 ( 1 ) page： 314   2021.6

Platelet counts during normal pregnancies and pregnancies complicated with hypertensive disorders

Ushida Takafumi, Kotani Tomomi, Moriyama Yoshinori, Imai Kenji, Nakano-Kobayashi Tomoko, Kinoshita Fumie, Nakamura Noriyuki, Iitani Yukako, Yoshida Shigeru, Yamashita Mamoru, Kajiyama Hiroaki

PREGNANCY HYPERTENSION-AN INTERNATIONAL JOURNAL OF WOMENS CARDIOVASCULAR HEALTH   Vol. 24   page： 73 - 78   2021.6

Antenatal prediction models for short- and medium-term outcomes in preterm infants

Ushida Takafumi, Moriyama Yoshinori, Nakatochi Masahiro, Kobayashi Yumiko, Imai Kenji, Nakano-Kobayashi Tomoko, Nakamura Noriyuki, Hayakawa Masahiro, Kajiyama Hiroaki, Kotani Tomomi

ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA   Vol. 100 ( 6 ) page： 1089 - 1096   2021.6

Significance of Concurrent Chemoradiotherapy as Primary Treatment in Patients with Metastatic Cervical Cancer

Hattori Satomi, Yoshikawa Nobuhisa, Mogi Kazumasa, Yoshida Kosuke, Yoshihara Masato, Tamauchi Satoshi, Ikeda Yoshiki, Yokoi Akira, Nishino Kimihiro, Niimi Kaoru, Suzuki Shiro, Kajiyama Hiroaki

CURRENT ONCOLOGY   Vol. 28 ( 3 ) page： 1663 - 1672   2021.6

Postpartum alterations following inflammation in rat pregnancy: a discovery proteomic analysis

Ushida Takafumi, Kotani Tomomi, Moriyama Yoshinori, Hindmarch Charles C. T., Cotechini Tiziana, Imai Kenji, Nakano-Kobayashi Tomoko, Kajiyama Hiroaki, Graham Charles H.

REPRODUCTION   Vol. 161 ( 5 ) page： 513 - 522   2021.5

A poor prognostic metastatic nongestational choriocarcinoma of the ovary: a case report and the literature review

Nishino Kimihiro, Yamamoto Eiko, Ikeda Yoshiki, Niimi Kaoru, Yamamoto Toshimichi, Kajiyama Hiroaki

JOURNAL OF OVARIAN RESEARCH   Vol. 14 ( 1 ) page： 56   2021.4

Vitamin D improves pulmonary function in a rat model for congenital diaphragmatic hernia

Ito Yumiko, Tsuda Hiroyuki, Imai Kenji, Miki Rika, Miura Mayo, Tachi Asuka, Tano Sho, Hirako-Takamura Shima, Moriyama Yoshinori, Ushida Takafumi, Kobayashi Tomoko, Sumigama Seiji, Kajiyama Hiroaki, Kikkawa Fumitaka, Kotani Tomomi

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS   Vol. 700   page： 108769   2021.3

ChrXq27.3 miRNA cluster functions in cancer development

Yoshida Kosuke, Yokoi Akira, Yamamoto Yusuke, Kajiyama Hiroaki

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH   Vol. 40 ( 1 ) page： 112   2021.3

Trisomy 5p with bilateral congenital diaphragmatic hernia: a case report

Nakamura Noriyuki, Ushida Takafumi, Moriyama Yoshinori, Imai Kenji, Nakano-Kobayashi Tomoko, Osuka Satoko, Goto Maki, Kajiyama Hiroaki, Asada Hideyuki, Hayakawa Masahiro, Kotani Tomomi

JOURNAL OF MEDICAL CASE REPORTS   Vol. 15 ( 1 ) page： 114   2021.3

Shock Index and Postpartum Hemorrhage in Vaginal Deliveries: A Multicenter Retrospective Study

Ushida Takafumi, Kotani Tomomi, Imai Kenji, Nakano-Kobayashi Tomoko, Nakamura Noriyuki, Moriyama Yoshinori, Yoshida Shigeru, Yamashita Mamoru, Kajiyama Hiroaki, Kikkawa Fumitaka

SHOCK   Vol. 55 ( 3 ) page： 332 - 337   2021.3

Maternal low birth weight and hypertensive disorders of pregnancy

Ushida Takafumi, Kotani Tomomi, Kinoshita Fumie, Imai Kenji, Nakano-Kobayashi Tomoko, Nakamura Noriyuki, Moriyama Yoshinori, Yoshida Shigeru, Yamashita Mamoru, Kajiyama Hiroaki

PREGNANCY HYPERTENSION-AN INTERNATIONAL JOURNAL OF WOMENS CARDIOVASCULAR HEALTH   Vol. 23   page： 5 - 10   2021.3

Preclinical Verification of the Efficacy and Safety of Aqueous Plasma for Ovarian Cancer Therapy

Nakamura Kae, Yoshikawa Nobuhisa, Mizuno Yuko, Ito Miwa, Tanaka Hiromasa, Mizuno Masaaki, Toyokuni Shinya, Hori Masaru, Kikkawa Fumitaka, Kajiyama Hiroaki

CANCERS   Vol. 13 ( 5 )   2021.3

Does complete-staging lymphadenectomy improve survival outcomes in stage I endometrioid epithelial ovarian carcinoma? A multi-institutional retrospective study with propensity score-weighted analysis

Yoshihara Masato, Tamauchi Satoshi, Iyoshi Shohei, Kitami Kazuhisa, Uno Kaname, Tano Sho, Matsui Shigeyuki, Kajiyama Hiroaki

JAPANESE JOURNAL OF CLINICAL ONCOLOGY   Vol. 51 ( 3 ) page： 387 - 392   2021.3

Ovarian Cancer-Associated Mesothelial Cells: Transdifferentiation to Minions of Cancer and Orchestrate Developing Peritoneal Dissemination

Mogi Kazumasa, Yoshihara Masato, Iyoshi Shohei, Kitami Kazuhisa, Uno Kaname, Tano Sho, Koya Yoshihiro, Sugiyama Mai, Yamakita Yoshihiko, Nawa Akihiro, Tomita Hiroyuki, Kajiyama Hiroaki

CANCERS   Vol. 13 ( 6 )   2021.3

Liver transaminase levels during pregnancy: a Japanese multicenter study

Ushida Takafumi, Kotani Tomomi, Kinoshita Fumie, Imai Kenji, Nakano-Kobayashi Tomoko, Nakamura Noriyuki, Moriyama Yoshinori, Yoshida Shigeru, Yamashita Mamoru, Kajiyama Hiroaki

JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE     page： 1 - 7   2021.2

Expression of the chrXq27.3 miRNA cluster in recurrent ovarian clear cell carcinoma and its impact on cisplatin resistance

Yoshida Kosuke, Yokoi Akira, Sugiyama Mai, Oda Shingo, Kitami Kazuhisa, Tamauchi Satoshi, Ikeda Yoshiki, Yoshikawa Nobuhisa, Nishino Kimihiro, Niimi Kaoru, Suzuki Shiro, Kikkawa Fumitaka, Yokoi Tsuyoshi, Kajiyama Hiroaki

ONCOGENE   Vol. 40 ( 7 ) page： 1255 - 1268   2021.2

Extracellular miRNAs as Predictive Biomarkers for Glypican-3-Derived Peptide Vaccine Therapy Response in Ovarian Clear Cell Carcinoma

Ukai Mayu, Yokoi Akira, Yoshida Kosuke, Suzuki Shiro, Shibata Kiyosumi, Kikkawa Fumitaka, Nakatsura Tetsuya, Kajiyama Hiroaki

CANCERS   Vol. 13 ( 3 )   2021.2

Active vitamin D inhibits mesothelial-mesenchymal-transition accelerating peritoneal dissemination in ovarian cancer

Kitami Kazuhisa, Yoshihara Masato, Sugiyama Mai, Koya Yoshihiro, Iyoshi Shohei, Uno Kaname, Mogi Kazumasa, Tamauchi Satoshi, Yokoi Akira, Yoshikawa Nobuhisa, Nawa Akihiro, Kajiyama Hiroaki

CANCER SCIENCE   Vol. 112   page： 351 - 351   2021.2

Establishment of a patient-derived xenograft model and cell line of malignant transformation of mature cystic teratoma of the ovary

Tamauchi Satoshi, Suzuki Shiro, Xuboya Chang, Yoshihara Masato, Yoshida Kosuke, Ikeda Yoshiki, Yoshikawa Nobuhisa, Kajiyama Hiroaki, Kikkawa Fumitaka

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH   Vol. 47 ( 2 ) page： 713 - 719   2021.2

Anti-tumor effect of 9-oxo-10,12-ODA on human cervical cancer cells

Koya Yoshihiro, Sugiyama Mai, Yoshihara Masato, Shibata Kiyosumi, Nawa Akihiro, Kajiyama Hiroaki

CANCER SCIENCE   Vol. 112   page： 826 - 826   2021.2

How do peritoneal mesothelial cells on adipose tissue attract ovarian cancer cells?

Mogi Kazumasa, Yoshihara Masato, Kitami Kazuhisa, Iyoshi Shohei, Uno Kaname, Tano Sho, Sugiyama Mai, Koya Yoshihiro, Tamauchi Satoshi, Yokoi Akira, Yoshikawa Nobuhisa, Nawa Akihiro, Kajiyama Hiroaki

CANCER SCIENCE   Vol. 112   page： 341 - 341   2021.2

Multiple cytokine analysis in gastroschisis: Association with adverse outcomes including fetal brain damage

Owaki Taro, Imai Kenji, Miki Rika, Niwa Yuri, Kotani Tomomi, Nakano-Kobayashi Tomoko, Ushida Takafumi, Kajiyama Hiroaki

CYTOKINE   Vol. 138   page： 155406   2021.2

Luteolin suppresses Ovarian Cancer progression via decrease the expression of VRK1

Chang Xuboya, Kajiyama Hiroaki, Yoshikawa Nobuhisa, Yokoi Akira, Tamauchi Satoshi, Yoshihara Masato

CANCER SCIENCE   Vol. 112   page： 770 - 770   2021.2

Intra-tumoral polarity induced by Notch signaling can be a novel therapeutic target for advanced ovarian cancer

Yoshihara Masato, Sugiyama Mai, Koya Yoshihiro, Iyoshi Shohei, Kitami Kazuhisa, Uno Kaname, Mogi Kazumasa, Tano Sho, Tamauchi Satoshi, Yokoi Akira, Yoshikawa Nobuhisa, Nawa Akihiro, Kajiyama Hiroaki

CANCER SCIENCE   Vol. 112   page： 363 - 363   2021.2

The role of chrXq27.3 miRNA cluster in advanced ovarian clear cell carcinoma

Yoshida Kosuke, Yokoi Akira, Yoshihara Masato, Tamauchi Satoshi, Yoshikawa Nobuhisa, Nishino Kimihiro, Niimi Kaoru, Kikkawa Fumitaka, Kajiyama Hiroaki

CANCER SCIENCE   Vol. 112   page： 291 - 291   2021.2

Visualization of platinum resistance through mapping trace elements

Uno Kaname, Yoshikawa Nobuhisa, Yoshihara Masato, Tazaki Kei, Kato Masashi, Kitami Kazuhisa, Iyoshi Shohei, Tamauchi Satoshi, Sugiyama Mai, Koya Yoshihiro, Kajiyama Hiroaki

CANCER SCIENCE   Vol. 112   page： 906 - 906   2021.2

Mortality and neurological outcomes in extremely and very preterm infants born to mothers with hypertensive disorders of pregnancy

Nakamura Noriyuki, Ushida Takafumi, Nakatochi Masahiro, Kobayashi Yumiko, Moriyama Yoshinori, Imai Kenji, Nakano-Kobayashi Tomoko, Hayakawa Masahiro, Kajiyama Hiroaki, Kikkawa Fumitaka, Kotani Tomomi

SCIENTIFIC REPORTS   Vol. 11 ( 1 ) page： 1729   2021.1

A uterine pseudotumor of immunoglobulinG4-related disease

Senda Yasutaka, Ikeda Yoshiki, Tamauchi Satoshi, Yoshikawa Nobuhisa, Kikkawa Fumitaka, Kajiyama Hiroaki

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH   Vol. 47 ( 1 ) page： 430 - 435   2021.1

The Prognostic Significance of Peritumoral Lymphocytes' Band-like Structure in Type II Endometrial Cancer

Shimizu Yusuke, Suzuki Shiro, Ukai Mayu, Hattori Satomi, Yoshikawa Nobuhisa, Kajiyama Hiroaki

ANTICANCER RESEARCH   Vol. 41 ( 1 ) page： 249 - 258   2021.1

Cancer Treatments Using Low-Temperature Plasma

Tanaka Hiromasa, Mizuno Masaaki, Ishikawa Kenji, Toyokuni Shinya, Kajiyama Hiroaki, Kikkawa Fumitaka, Hori Masaru

CURRENT MEDICINAL CHEMISTRY   Vol. 28 ( 41 ) page： 8549 - 8558   2021

[Promotion of Equal Access to Medical Services for Children, Adolescent and Young Adult(CAYA)Cancer Patients with Reproductive Problems-A Nationwide Expansion of the Regional Oncofertility Network in Japan].

Takenaka M, Furui T, Takae S, Sugishita Y, Kawahara T, Shigematsu K, Kimura F, Horie A, Hara T, Kato M, Nishiyama H, Suzuki T, Miyachi M, Kanenishi K, Kubo K, Nakayama S, Kajiyama H, Takai Y, Suzuki N

Gan to kagaku ryoho. Cancer & chemotherapy   Vol. 47 ( 12 ) page： 1691 - 1696   2020.12

Efficacy of 5-aminolevulinic acid and LED photodynamic therapy in cervical intraepithelial neoplasia: A clinical trial

Mizuno Mika, Mitsui Hiroko, Kajiyama Hiroaki, Teshigawara Toshiya, Inoue Katsushi, Takahashi Kiwamu, Ishii Takuya, Ishizuka Masahiro, Nakajima Motowo, Kikkawa Fumitaka

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY   Vol. 32   page： 102004   2020.12

Microphthalmia-Associated Transcription Factor-Dependent Melanoma Cell Adhesion Molecule Activation Promotes Peritoneal Metastasis of Ovarian Cancer

Kitami Kazuhisa, Yoshihara Masato, Koya Yoshihiro, Sugiyama Mai, Iyoshi Shohei, Uno Kaname, Mogi Kazumasa, Tano Sho, Fujimoto Hiroki, Nawa Akihiro, Kikkawa Fumitaka, Kajiyama Hiroaki

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES   Vol. 21 ( 24 )   2020.12

Sarcopenia as a Predictor of Survival Among Patients With Organ Metastatic Cervical Cancer

Yoshikawa Nobuhisa, Shirakawa Akira, Yoshida Kosuke, Tamauchi Satoshi, Suzuki Shiro, Kikkawa Fumitaka, Kajiyama Hiroaki

NUTRITION IN CLINICAL PRACTICE   Vol. 35 ( 6 ) page： 1041 - 1046   2020.12

Does uterine preservation affect survival outcomes of patients with stage I ovarian sex cord-stromal cell tumours? A multi-institutional study

Yoshihara Masato, Tamauchi Satoshi, Iyoshi Shohei, Kitami Kazuhisa, Uno Kaname, Yoshikawa Nobuhisa, Ikeda Yoshiki, Kawai Michiyasu, Nagasaka Tetsuro, Kajiyama Hiroaki

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY   Vol. 254   page： 52 - 56   2020.11

Establishment and characterization of cell lines from human endometrial epithelial and mesenchymal cells from patients with endometriosis.

Muraoka A, Osuka S, Kiyono T, Suzuki M, Yokoi A, Murase T, Nishino K, Niimi K, Nakamura T, Goto M, Kajiyama H, Kondo Y, Kikkawa F

F&S science   Vol. 1 ( 2 ) page： 195 - 205   2020.11

Adjusted multiple gases in the plasma flow induce differential antitumor potentials of plasma-activated solutions

Nakamura Kae, Yoshikawa Nobuhisa, Yoshihara Masato, Ikeda Yoshiki, Higashida Akihiro, Niwa Akihiro, Jindo Takahiro, Tanaka Hiromasa, Ishikawa Kenji, Mizuno Masaaki, Toyokuni Shinya, Hori Masaru, Kikkawa Fumitaka, Kajiyama Hiroaki

PLASMA PROCESSES AND POLYMERS   Vol. 17 ( 10 )   2020.10

Macrophage-derived extracellular vesicles regulate concanavalin A-induced hepatitis by suppressing macrophage cytokine production

Kawata Reo, Oda Shingo, Koya Yoshihiro, Kajiyama Hiroaki, Yokoi Tsuyoshi

TOXICOLOGY   Vol. 443   page： 152544   2020.10

Novel ovarian endometriosis model causes infertility via iron-mediated oxidative stress in mice

Hayashi Shotaro, Nakamura Tomoko, Motooka Yashiro, Ito Fumiya, Jiang Li, Akatsuka Shinya, Iwase Akira, Kajiyama Hiroaki, Kikkawa Fumitaka, Toyokuni Shinya

REDOX BIOLOGY   Vol. 37   page： 101726   2020.10

Long non-coding RNA: A recently accentuated molecule in chemoresistance in cancer

Peng Yang, Tang Dihong, Zhao Meng, Kajiyama Hiroaki, Kikkawa Fumitaka, Kondo Yutaka

CANCER AND METASTASIS REVIEWS   Vol. 39 ( 3 ) page： 825 - 835   2020.9

Follicular dendritic cell sarcoma of the uterine cervix: a case report

Nakamura Takuto, Yoshihara Masato, Tamauchi Satoshi, Kajiyama Hiroaki, Kikkawa Fumitaka

BMC WOMENS HEALTH   Vol. 20 ( 1 ) page： 182   2020.8

Survival after Anticancer Treatment of Terminally Ill Patients with Ovarian Carcinoma

Kajiyama Hiroaki, Suzuki Shiro, Shimbo Akiko, Utsumi Fumi, Yoshikawa Nobuhisa, Kikkawa Fumitaka

JOURNAL OF PALLIATIVE MEDICINE   Vol. 23 ( 8 ) page： 1060 - 1065   2020.8

Impact of uterus-preserving surgery on Stage I primary mucinous epithelial ovarian carcinoma: A multi-institutional study with propensity score-weighted analysis

Yoshihara Masato, Kajiyama Hiroaki, Tamauchi Satoshi, Iyoshi Shohei, Yokoi Akira, Suzuki Shiro, Kawai Michiyasu, Nagasaka Tetsuro, Takahashi Kunihiko, Matsui Shigeyuki, Kikkawa Fumitaka

INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS   Vol. 150 ( 2 ) page： 177 - 183   2020.8

Non-thermal plasma-activated lactate solution kills U251SP glioblastoma cells in an innate reductive manner with altered metabolism

Ishikawa Kenji, Hosoi Yugo, Tanaka Hiromasa, Jiang Li, Toyokuni Shinya, Nakamura Kae, Kajiyama Hiroaki, Kikkawa Fumitaka, Mizuno Masaaki, Hori Masaru

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS   Vol. 688   page： 108414   2020.7

Filopodia play an important role in the trans-mesothelial migration of ovarian cancer cells

Yoshihara Masato, Yamakita Yoshihiko, Kajiyama Hiroaki, Senga Takeshi, Koya Yoshihiro, Yamashita Mamoru, Nawa Akihiro, Kikkawa Fumitaka

EXPERIMENTAL CELL RESEARCH   Vol. 392 ( 2 ) page： 112011   2020.7

Exploration of small RNA biomarkers for testicular injury in the serum exosomes of rats

Kawata Reo, Kagawa Takumi, Koya Yoshihiro, Kajiyama Hiroaki, Oda Shingo, Yokoi Tsuyoshi

TOXICOLOGY   Vol. 440   page： 152490   2020.7

The impact of systematic retroperitoneal lymphadenectomy on long-term oncologic outcome of women with advanced ovarian clear-cell carcinoma

Kajiyama Hiroaki, Suzuki Shiro, Yoshikawa Nobuhisa, Tamauchi Satoshi, Shibata Kiyosumi, Kikkawa Fumitaka

JOURNAL OF GYNECOLOGIC ONCOLOGY   Vol. 31 ( 4 ) page： e47   2020.7

The management of hydatidiform mole using prophylactic chemotherapy and hysterectomy for high-risk patients decreased the incidence of gestational trophoblastic neoplasia in Vietnam: a retrospective observational study

Yamamoto Eiko, Tien Dat Minh, Sekiya Yoko, Tamakoshi Koji, Xuan Phuoc Nguyen, Nishino Kimihiro, Kotani Kaoru Tomomi, Kajiyama Hiroaki, Shibata Kiyosumi, Quang Thanh Le, Kikkawa Fumitaka

NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 82 ( 2 ) page： 183 - 191   2020.5

Clinical characteristics and surgical outcomes of retroperitoneal tumors: a comprehensive data collection from multiple departments

Sassa Naoto, Yokoyama Yukihiro, Nishida Yoshihiro, Yamada Suguru, Uchida Hiroo, Kajiyama Hiroaki, Nagino Masato, Kodera Yasuhiro, Gotoh Momokazu

INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY   Vol. 25 ( 5 ) page： 929 - 936   2020.5

Folate-appended cyclodextrin carrier targets ovarian cancer cells expressing the proton-coupled folate transporter

Saito Shinichi, Koya Yoshihiro, Kajiyama Hiroaki, Yamashita Mamoru, Kikkawa Fumitaka, Nawa Akihiro

CANCER SCIENCE   Vol. 111 ( 5 ) page： 1794 - 1804   2020.5

Pegylated Liposomal Doxorubicin/Oxaliplatin Chemotherapy Can Overcome Cisplatin Resistance in Spectrin alpha II-Overexpressing Ovarian Carcinoma

Maeda Osamu, Kajiyama Hiroaki, Shibata Kiyosumi, Nakamura Shigeo, Kikkawa Fumitaka

ANTICANCER RESEARCH   Vol. 40 ( 5 ) page： 2497 - 2507   2020.5

Is cell block technique useful to predict histological type in patients with ovarian mass and/or body cavity fluids?

Masekii Zenta, Kajiyama Hiroaki, Nishikawa Eri, Satake Tatsunari, Misawa Toshiya, Kikkawa Fumitaka

NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 82 ( 2 ) page： 225 - 235   2020.5

The Preoperative Prognostic Nutritional Index for the Prediction of Outcomes in Patients with Early-Stage Ovarian Clear Cell Carcinoma

Yoshikawa Nobuhisa, Yoshida Kosuke, Tamauchi Satoshi, Ikeda Yoshiki, Nishino Kimihiro, Niimi Kaoru, Suzuki Shiro, Kikkawa Fumitaka, Kajiyama Hiroaki

SCIENTIFIC REPORTS   Vol. 10 ( 1 ) page： 7135   2020.4

The Therapeutic Effects of Goreisan, a Traditional Japanese Herbal Medicine, on Lower-Limb Lymphedema after Lymphadenectomy in Gynecologic Malignancies: A Case Series Study

Yoshikawa Nobuhisa, Kajiyama Hiroaki, Otsuka Naoki, Tamauchi Satoshi, Ikeda Yoshiki, Nishino Kimihiro, Niimi Kaoru, Suzuki Shiro, Utsumi Fumi, Shibata Kiyosumi, Kikkawa Fumitaka

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE   Vol. 2020   page： 6298293   2020.4

Ovarian cancer-associated mesothelial cells induce acquired platinum-resistance in peritoneal metastasis via the FN1/Akt signaling pathway

Yoshihara Masato, Kajiyama Hiroaki, Yokoi Akira, Sugiyama Mai, Koya Yoshihiro, Yamakita Yoshihiko, Liu Wenting, Nakamura Kae, Moriyama Yoshinori, Yasui Hiroaki, Suzuki Shiro, Yamamoto Yusuke, Ricciardelli Carmela, Nawa Akihiro, Shibata Kiyosumi, Kikkawa Fumitaka

INTERNATIONAL JOURNAL OF CANCER   Vol. 146 ( 8 ) page： 2268 - 2280   2020.4

How do doctors choose treatment for older gynecological cancer patients? A Japanese Gynecologic Oncology Group survey of gynecologic oncologists

Yamamoto Makoto, Yoshida Yoshio, Itani Yoshio, Sato Shinya, Futagami Masayuki, Sakai Hitomi, Kajiyama Hiroaki, Ura Masaki Fujim, Aoki Yoichi

INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY   Vol. 25 ( 4 ) page： 741 - 745   2020.4

Is standard radical surgery necessary for elderly patients with early-stage epithelial ovarian carcinoma? similar to Propensity score matched analysis similar to

Kajiyama Hiroaki, Yoshihara Masato, Tamauchi Satoshi, Yoshikawa Nobuhisa, Niimi Kaoru, Suzuki Shiro, Shibata Kiyosumi, Kikkawa Fumitaka

JAPANESE JOURNAL OF CLINICAL ONCOLOGY   Vol. 50 ( 4 ) page： 411 - 418   2020.4

Japan society of clinical oncology/Japanese society of medical oncology-led clinical recommendations on the diagnosis and use of tropomyosin receptor kinase inhibitors in adult and pediatric patients with neurotrophic receptor tyrosine kinase fusion-positive advanced solid tumors, cooperated by the Japanese society of pediatric hematology/oncology

Naito Yoichi, Mishima Saori, Akagi Kiwamu, Igarashi Ataru, Ikeda Masafumi, Okano Susumu, Kato Shunsuke, Takano Tadao, Tsuchihara Katsuya, Terashima Keita, Nishihara Hiroshi, Nishiyama Hiroyki, Hiyama Eiso, Hirasawa Akira, Hosoi Hajime, Maeda Osamu, Yatabe Yasushi, Okamoto Wataru, Ono Shigeru, Kajiyama Hiroaki, Nagashima Fumio, Hatanaka Yutaka, Miyachi Mitsuru, Kodera Yasuhiro, Yoshino Takayuki, Taniguchi Hiroya

INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY   Vol. 25 ( 3 ) page： 403 - 417   2020.3

CCL2 secreted from cancer-associated mesothelial cells promotes peritoneal metastasis of ovarian cancer cells through the P38-MAPK pathway

Yasui Hiroaki, Kajiyama Hiroaki, Tamauchi Satoshi, Suzuki Shiro, Peng Yang, Yoshikawa Nobuhisa, Sugiyama Mai, Nakamura Kae, Kikkawa Fumitaka

CLINICAL & EXPERIMENTAL METASTASIS   Vol. 37 ( 1 ) page： 145 - 158   2020.2

Prognostic impact of pelvic and para-aortic lymphadenectomy on clinically-apparent stage I primary mucinous epithelial ovarian carcinoma: a multi-institutional study with propensity score-weighted analysis

Yoshihara Masato, Kajiyama Hiroaki, Tamauchi Satoshi, Iyoshi Shohei, Yokoi Akira, Suzuki Shiro, Kawai Michiyasu, Nagasaka Tetsuro, Takahashi Kunihiko, Matsui Shigeyuki, Kikkawa Fumitaka

JAPANESE JOURNAL OF CLINICAL ONCOLOGY   Vol. 50 ( 2 ) page： 145 - 151   2020.2

The role of additional hysterectomy after concurrent chemoradiation for patients with locally advanced cervical cancer

Yoshida Kosuke, Kajiyama Hiroaki, Yoshihara Masato, Tamauchi Satoshi, Ikeda Yoshiki, Yoshikawa Nobuhisa, Nishino Kimihiro, Niimi Kaoru, Suzuki Shiro, Kikkawa Fumitaka

INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY   Vol. 25 ( 2 ) page： 384 - 390   2020.2

Plasma-activated medium promotes autophagic cell death along with alteration of the mTOR pathway

Yoshikawa Nobuhisa, Liu Wenting, Nakamura Kae, Yoshida Kosuke, Ikeda Yoshiki, Tanaka Hiromasa, Mizuno Masaaki, Toyokuni Shinya, Hori Masaru, Kikkawa Fumitaka, Kajiyama Hiroaki

SCIENTIFIC REPORTS   Vol. 10 ( 1 ) page： 1614   2020.1

Impact of age on clinicopathological features and survival of epithelial ovarian neoplasms in reproductive age

Hanatani Maya, Yoshikawa Nobuhisa, Yoshida Kosuke, Tamauchi Satoshi, Ikeda Yoshiki, Nishino Kimihiro, Niimi Kaoru, Suzuki Shiro, Kawai Michiyasu, Kajiyama Hiroaki, Kikkawa Fumitaka

INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY   Vol. 25 ( 1 ) page： 187 - 194   2020.1

The efficacy and toxicity of 4-day chemotherapy with methotrexate, etoposide and actinomycin D in patients with choriocarcinoma and high-risk gestational trophoblastic neoplasia

Sato Shizuka, Yamamoto Eiko, Niimi Kaoru, Ino Kazuhiko, Nishino Kimihiro, Suzuki Shiro, Kotani Tomomi, Kajiyama Hiroaki, Kikkawa Fumitaka

INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY   Vol. 25 ( 1 ) page： 203 - 209   2020.1

Clinical Significance of Ubiquitin-associated Protein 2-like in Patients With Uterine Cervical Cancer

Yoshida Kosuke, Kajiyama Hiroaki, Inami Eri, Tamauchi Satoshi, Ikeda Yoshiki, Yoshikawa Nobuhisa, Nishino Kimihiro, Utsumi Fumi, Niimi Kaoru, Suzuki Shiro, Shibata Kiyosumi, Nawa Akihiro, Kikkawa Fumitaka

IN VIVO   Vol. 34 ( 1 ) page： 109 - 116   2020

Complete Response of Recurrent Small Cell Carcinoma of the Uterine Cervix to Paclitaxel, Carboplatin, and Bevacizumab Combination Therapy

Nakao Yuri, Tamauchi Satoshi, Yoshikawa Nobuhisa, Suzuki Shiro, Kajiyama Hiroaki, Kikkawa Fumitaka

CASE REPORTS IN ONCOLOGY   Vol. 13 ( 1 ) page： 373 - 378   2020

Fertility-sparing surgery and oncologic outcome among patients with early-stage ovarian cancer similar to propensity score- matched analysis similar to

Kajiyama Hiroaki, Suzuki Shiro, Yoshikawa Nobuhisa, Kawai Michiyasu, Mizuno Kimio, Yamamuro Osamu, Nagasaka Tetsuro, Shibata Kiyosumi, Kikkawa Fumitaka

BMC CANCER   Vol. 19 ( 1 ) page： 1235   2019.12

Unique miRNA profiling of squamous cell carcinoma arising from ovarian mature teratoma: comprehensive miRNA sequence analysis of its molecular background

Yoshida Kosuke, Yokoi Akira, Kagawa Takumi, Oda Shingo, Hattori Satomi, Tamauchi Satoshi, Ikeda Yoshiki, Yoshikawa Nobuhisa, Nishino Kimihiro, Utsumi Fumi, Niimi Kaoru, Suzuki Shiro, Shibata Kiyosumi, Kajiyama Hiroaki, Yokoi Tsuyoshi, Kikkawa Fumitaka

CARCINOGENESIS   Vol. 40 ( 12 ) page： 1435 - 1444   2019.12

Expression of connective tissue growth factor as a prognostic indicator and its possible involvement in the aggressive properties of epithelial ovarian carcinoma

Shimbo Akiko, Kajiyama Hiroaki, Tamauchi Satoshi, Yoshikawa Nobuhisa, Ikeda Yoshiki, Nishino Kimihiro, Suzuki Shiro, Niimi Kaoru, Sakata Jun, Kikkawa Fumitaka

ONCOLOGY REPORTS   Vol. 42 ( 6 ) page： 2323 - 2332   2019.12

The usefulness of bevacizumab for relief from symptomatic malignant ascites in patients with heavily treated recurrent ovarian cancer

Shimizu Yusuke, Kajiyama Hiroaki, Yoshida Kosuke, Tamauchi Satoshi, Nakanishi Toru, Kikkawa Fumitaka

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH   Vol. 45 ( 12 ) page： 2435 - 2439   2019.12

COMPREHENSIVE MIRNA SEQUENCING OF SQUAMOUS CELL CARCINOMA ARISING FROM OVARIAN MATURE TERATOMA

Yoshida K., Yokoi A., Tamauchi S., Ikeda Y., Yoshikawa N., Nishino K., Niimi K., Suzuki S., Kajiyama H., Kikkawa F.

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER   Vol. 29   page： A544 - A545   2019.11

Prognostic factors and effects of fertility-sparing surgery in women of reproductive age with ovarian clear-cell carcinoma: a propensity score analysis

Yoshihara Masato, Kajiyama Hiroaki, Tamauchi Satoshi, Suzuki Shiro, Takahashi Kunihiko, Matsui Shigeyuki, Kikkawa Fumitaka

JOURNAL OF GYNECOLOGIC ONCOLOGY   Vol. 30 ( 6 ) page： e102   2019.11

REDUCED RESPONSE TO CONTROLLED OVARIAN STIMULATION AFTER RADICAL TRACHELECTOMY

Tamauchi S., Kajiyama H., Osuka S., Moriyama Y., Yoshihara M., Iyoshi S., Yoshida K., Ikeda Y., Yoshikawa N., Nishino K., Niimi K., Suzuki S., Kikkawa F.

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER   Vol. 29   page： A269 - A270   2019.11

Prognostic value of neutrophil-to-lymphocyte ratio in early-stage ovarian clear-cell carcinoma

Yoshida Kosuke, Yoshikawa Nobuhisa, Shirakawa Akira, Niimi Kaoru, Suzuki Shiro, Kajiyama Hiroaki, Kikkawa Fumitaka

JOURNAL OF GYNECOLOGIC ONCOLOGY   Vol. 30 ( 6 ) page： e85   2019.11

Fertility-Sparing surgery for young women with ovarian endometrioid carcinoma: a multicenteric comparative study using inverse probability of treatment weighting.

Kajiyama H, Yoshihara M, Tamauchi S, Yoshikawa N, Suzuki S, Kikkawa F

European journal of obstetrics & gynecology and reproductive biology: X   Vol. 4   page： 100071   2019.10

Relationship between preexisting mental disorders and prognosis of gynecologic cancers: A case-control study

Tamauchi Satoshi, Kajiyama Hiroaki, Moriyama Yoshinori, Yoshihara Masato, Ikeda Yoshiki, Yoshikawa Nobuhisa, Nishino Kimihiro, Niimi Kaoru, Suzuki Shiro, Kikkawa Fumitaka

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH   Vol. 45 ( 10 ) page： 2082 - 2087   2019.10

Oxidative stress-dependent and -independent death of glioblastoma cells induced by non-thermal plasma-exposed solutions

Tanaka Hiromasa, Mizuno Masaaki, Katsumata Yuko, Ishikawa Kenji, Kondo Hiroki, Hashizume Hiroshi, Okazaki Yasumasa, Toyokuni Shinya, Nakamura Kae, Yoshikawa Nobuhisa, Kajiyama Hiroaki, Kikkawa Fumitaka, Hori Masaru

SCIENTIFIC REPORTS   Vol. 9 ( 1 ) page： 13657   2019.9

Long-term oncologic outcome and its prognostic indicators in reproductive-age women with ovarian clear-cell carcinoma

Kajiyama Hiroaki, Suzuki Shiro, Yoshikawa Nobuhisa, Niimi Kaoru, Kawai Michiyasu, Shibata Kiyosumi, Kikkawa Fumitaka

ARCHIVES OF GYNECOLOGY AND OBSTETRICS   Vol. 300 ( 3 ) page： 717 - 724   2019.9

Interleukin-33 expression in ovarian cancer and its possible suppression of peritoneal carcinomatosis

Sekiya Atsushi, Suzuki Shiro, Tanaka Ayako, Hattori Satomi, Shimizu Yusuke, Yoshikawa Nobuhisa, Koya Yoshihiro, Kajiyama Hiroaki, Kikkawa Fumitaka

INTERNATIONAL JOURNAL OF ONCOLOGY   Vol. 55 ( 3 ) page： 755 - 765   2019.9

Comparison of long-term oncologic outcomes between metastatic ovarian carcinoma originating from gastrointestinal organs and advanced mucinous ovarian carcinoma

Kajiyama Hiroaki, Suzuki Shiro, Utsumi Fumi, Yoshikawa Nobuhisa, Nishino Kimihiro, Ikeda Yoshiki, Niimi Kaoru, Yamamoto Eiko, Kawai Michiyasu, Shibata Kiyosumi, Nagasaka Tetsuro, Kikkawa Fumitaka

INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY   Vol. 24 ( 8 ) page： 950 - 956   2019.8

Oncologic and reproductive outcomes of cystectomy as a fertility-sparing treatment for early-stage epithelial ovarian cancer

Kajiyama Hiroaki, Suzuki Shiro, Niimi Kaoru, Tamauchi Satoshi, Kawai Michiyasu, Nagasaka Tetsuro, Shibata Kiyosumi, Kikkawa Fumitaka

INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY   Vol. 24 ( 7 ) page： 857 - 862   2019.7

Oncologic outcomes after secondary surgery in recurrent clear-cell carcinoma of the ovary

Kajiyama Hiroaki, Suzuki Shiro, Yoshikawa Nobuhisa, Kawai Michiyasu, Shibata Kiyosumi, Nagasaka Tetsuro, Kikkawa Fumitaka

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER   Vol. 29 ( 5 ) page： 910 - 915   2019.6

Epidemiological overview of metastatic ovarian carcinoma: long-term experience of TOTSG database

Kajiyama Hiroaki, Suzuki Shiro, Utsumi Fumi, Nishino Kimihiro, Niimi Kaoru, Mizuno Mika, Yoshikawa Nobuhisa, Kawai Michiyasu, Oguchi Hidenori, Mizuno Kimio, Yamamuro Osamu, Shibata Kiyosumi, Nagasaka Tetsuro, Kikkawa Fumitaka

NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 81 ( 2 ) page： 193 - 198   2019.5

Does postoperative prophylactic irradiation of para-aortic lymph nodes reduce the risk of recurrence in uterine cervical cancer with positive pelvic lymph nodes?

Yoshida Kosuke, Kajiyama Hiroaki, Yoshihara Masato, Ikeda Yoshiki, Yoshikawa Nobuhisa, Nishino Kimihiro, Utsumi Fumi, Niimi Kaoru, Suzuki Shiro, Kikkawa Fumitaka

INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY   Vol. 24 ( 5 ) page： 567 - 574   2019.5

Urinary levels of the leukocyte surface molecule CD11b associate with glomerular inflammation in lupus nephritis

Kitagawa Akimitsu, Tsuboi Naotake, Yokoe Yuki, Katsuno Takayuki, Ikeuchi Hidekazu, Kajiyama Hiroshi, Endo Nobuhide, Sawa Yuriko, Suwa Junya, Sugiyama Yutaka, Hachiya Asaka, Mimura Toshihide, Hiromura Keiju, Maruyama Shoichi

KIDNEY INTERNATIONAL   Vol. 95 ( 3 ) page： 680 - 692   2019.3

Endometriosis and cancer

Kajiyama Hiroaki, Suzuki Shiro, Yoshihara Masato, Tamauchi Satoshi, Yoshikawa Nobuhisa, Niimi Kaoru, Shibata Kiyosumi, Kikkawa Fumitaka

FREE RADICAL BIOLOGY AND MEDICINE   Vol. 133   page： 186 - 192   2019.3

Survival impact of capsule status in stage I ovarian mucinous carcinoma-A mulicentric retrospective study

Kajiyama Hiroaki, Suzuki Shiro, Yoshikawa Nobuhisa, Kawai Michiyasu, Nagasaka Tetsuro, Kikkawa Fumitaka

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY   Vol. 234   page： 131 - 136   2019.3

Non-thermal plasma-activated medium modified metabolomic profiles in the glycolysis of U251SP glioblastoma

Kurake Naoyuki, Ishikawa Kenji, Tanaka Hiromasa, Hashizume Hiroshi, Nakamura Kae, Kajiyama Hiroaki, Toyokuni Shinya, Kikkawa Fumitaka, Mizuno Masaaki, Hori Masaru

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS   Vol. 662   page： 83 - 92   2019.2

PAI-1 secreted from metastatic ovarian cancer cells triggers the tumor-promoting role of the mesothelium in a feedback loop to accelerate peritoneal dissemination

Peng Yang, Kajiyama Hiroaki, Yuan Hong, Nakamura Kae, Yoshihara Masato, Yokoi Akira, Fujikake Kayo, Yasui Hiroaki, Yoshikawa Nobuhisa, Suzuki Shiro, Senga Takeshi, Shibata Kiyosumi, Kikkawa Fumitaka

CANCER LETTERS   Vol. 442   page： 181 - 192   2019.2

Estrogen producing ovarian fibrosarcoma: A case report

Miura Mayo, Suzuki Shiro, Shibata Kiyosumi, Kajiyama Hiroaki, Kikkawa Fumitaka

NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 81 ( 1 ) page： 171 - 176   2019.2

Molecular mechanisms of non-thermal plasmainduced effects in cancer cells

Tanaka Hiromasa, Mizuno Masaaki, Ishikawa Kenji, Toyokuni Shinya, Kajiyama Hiroaki, Kikkawa Fumitaka, Hori Masaru

BIOLOGICAL CHEMISTRY   Vol. 400 ( 1 ) page： 87 - 91   2019.1

The role of extracellular RNAs in ovarian cancer

Yokoi Akira, Yoshioka Yusuke, Yamamoto Yusuke, Matsuzaki Juntaro, Kato Tomoyasu, Kato Ken, Kajiyama Hiroaki, Kikkawa Fumitaka, Ochiya Takahiro

CANCER SCIENCE   Vol. 109   page： 351 - 351   2018.12

Cancer-associated mesothelial cells as a potential therapeutic target in epithelial ovarian cancer

Yoshihara Masato, Kajiyama Hiroaki, Sugiyama Mai, Koya Yoshihiro, Ryu Buntei, Yokoi Akira, Yamamoto Yusuke, Kikkawa Fumitaka

CANCER SCIENCE   Vol. 109   page： 247 - 247   2018.12

Mesothelial cells create invasion frontier in peritoneal metastasis of epithelial ovarian cancer

Iyoshi Shohei, Kajiyama Hiroaki, Yoshihara Masato, Yamakita Yoshihiko, Sugiyama Mai, Koya Yoshihiro, Ryu Buntei, Kikkawa Fumitaka

CANCER SCIENCE   Vol. 109   page： 282 - 282   2018.12

Notch signaling enhances the mutual association with epithelial ovarian cancer and mesothelial cells

Sugiyama Mai, Yoshihara Masato, Koya Yoshihiro, Yokoi Akira, Ryu Buntei, Kikkawa Fumitaka, Kajiyama Hiroaki

CANCER SCIENCE   Vol. 109   page： 864 - 864   2018.12

MITF contributes to cell migration/invasion in ovarian carcinoma cells

Koya Yoshihiro, Ryu Buntei, Sugiyama Mai, Yoshihara Masato, Senga Takeshi, Nawa Akihiro, Kikkawa Fumitaka, Kajiyama Hiroaki

CANCER SCIENCE   Vol. 109   page： 503 - 503   2018.12

Reproductive outcomes of 105 malignant ovarian germ cell tumor survivors: a multicenter study

Tamauchi Satoshi, Kajiyama Hiroaki, Yoshihara Masato, Ikeda Yoshiki, Yoshikawa Nobuhisa, Nishino Kimihiro, Utsumi Fumi, Niimi Kaoru, Suzuki Shiro, Kikkawa Fumitaka

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY   Vol. 219 ( 4 ) page： 385.e1 - 385.e7   2018.10

CANCER-ASSOCIATED MESOTHELIAL CELLS IN PERITONEAL METASTASIS OF EPITHELIAL OVARIAN CANCER AS A NOVEL THERAPEUTIC TARGET: 3D CO-CULTURE MODELS AND MULTI-OMICS ANALYSIS

Masato Y., Kajiyama H., Yoshihiko Y., Mai S., Koya Y., Ryu B., Akira Y., Shiro S., Kikkawa F.

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER   Vol. 28   page： 187 - 188   2018.9

EFFECT OF CONCURRENT CHEMO-RADIOTHERAPY ON CLINICAL OUTCOMES IN SMALL CELL CARCINOMA OF THE UTERINE CERVIX

Ikeda Y., Kajiyama H., Yoshida K., Yoshikawa N., Nishino K., Utsumi F., Niimi K., Suzuki S., Kawai M., Kikkawa F.

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER   Vol. 28   page： 294 - 294   2018.9

PROPENSITY SCORE ADJUSTED ANALYSIS OF PROPHYLACTIC IRRADIATION TO PARA-AORTIC LYMPH NODE AFTER RADICAL HYSTERECTOMY FOR UTERINE CERVICAL CANCER.

Yoshida K., Yoshihara M., Ikeda Y., Yoshikawa N., Nishino K., Utumi F., Niimi K., Suzuki S., Kajiyama H., Kikkawa F.

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER   Vol. 28   page： 447 - 447   2018.9

Hematopoietic lineage cell-specific protein 1 (HS1), a hidden player in migration, invasion, and tumor formation, is over-expressed in ovarian carcinoma cells.

Koya Y, Liu W, Yamakita Y, Senga T, Shibata K, Yamashita M, Nawa A, Kikkawa F, Kajiyama H

Oncotarget   Vol. 9 ( 66 ) page： 32609 - 32623   2018.8

KIF20A expression as a prognostic indicator and its possible involvement in the proliferation of ovarian clear-cell carcinoma cells

Kawai Yosuke, Shibata Kiyosumi, Sakata Jun, Suzuki Shiro, Utsumi Fumi, Niimi Kaoru, Sekiya Ryuichiro, Senga Takeshi, Kikkawa Fumitaka, Kajiyama Hiroaki

ONCOLOGY REPORTS   Vol. 40 ( 1 ) page： 195 - 205   2018.7

The upregulated expression of vascular endothelial growth factor in surgically treated patients with recurrent/radioresistant cervical cancer of the uterus

Yoshida Kosuke, Suzuki Shiro, Sakata Jun, Utsumi Fumi, Niimi Kaoru, Yoshikawa Nobuhisa, Nishino Kimihiro, Shibata Kiyosumi, Kikkawa Fumitaka, Kajiyama Hiroaki

ONCOLOGY LETTERS   Vol. 16 ( 1 ) page： 515 - 521   2018.7

Fertility-sparing surgery of malignant transformation arising from mature cystic teratoma of the ovary.

Yoshikawa N, Teshigawara T, Ikeda Y, Nishino K, Sakata J, Utsumi F, Niimi K, Sekiya R, Suzuki S, Kawai M, Shibata K, Kikkawa F, Kajiyama H

Oncotarget   Vol. 9 ( 44 ) page： 27564 - 27573   2018.6

Hematopoietic lineage cell-specific protein 1 immunoreactivity indicates an increased risk of poor overall survival in patients with ovarian carcinoma

Liu Wenting, Kajiyama Hiroaki, Shibata Kiyosumi, Koya Yoshihiro, Senga Takeshi, Kikkawa Fumitaka

ONCOLOGY LETTERS   Vol. 15 ( 6 ) page： 9406 - 9412   2018.6

Dengue fever during pregnancy.

Tien Dat T, Kotani T, Yamamoto E, Shibata K, Moriyama Y, Tsuda H, Yamashita M, Kajiyama H, Duc Thien Minh D, Quang Thanh L, Kikkawa F

Nagoya journal of medical science   Vol. 80 ( 2 ) page： 241 - 247   2018.5

Dengue fever during pregnancy

Trinh Tien Dat, Kotani Tomomi, Yamamoto Eiko, Shibata Kiyosumi, Moriyama Yoshinori, Tsuda Hiroyuki, Yamashita Mamoru, Kajiyama Hiroaki, Dien Duc Thien Minh, Le Quang Thanh, Kikkawa Fumitaka

NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 80 ( 2 ) page： 241 - 247   2018.5

Connective tissue growth factor-specific monoclonal antibody inhibits growth of malignant mesothelioma in an orthotopic mouse model.

Ohara Y, Chew SH, Misawa N, Wang S, Somiya D, Nakamura K, Kajiyama H, Kikkawa F, Tsuyuki Y, Jiang L, Yamashita K, Sekido Y, Lipson KE, Toyokuni S

Oncotarget   Vol. 9 ( 26 ) page： 18494 - 18509   2018.4

Splicing variant of WDFY4 augments MDA5 signalling and the risk of clinically amyopathic dermatomyositis

Kochi Yuta, Kamatani Yoichiro, Kondo Yuya, Suzuki Akari, Kawakami Eiryo, Hiwa Ryosuke, Momozawa Yukihide, Fujimoto Manabu, Jinnin Masatoshi, Tanaka Yoshiya, Kanda Takashi, Cooper Robert G., Chinoy Hector, Rothwell Simon, Lamb Janine A., Vencovsky Jiri, Mann Herman, Ohmura Koichiro, Myouzen Keiko, Ishigaki Kazuyoshi, Nakashima Ran, Hosono Yuji, Tsuboi Hiroto, Kawasumi Hidenaga, Iwasaki Yukiko, Kajiyama Hiroshi, Horita Tetsuya, Ogawa-Momohara Mariko, Takamura Akito, Tsunoda Shinichiro, Shimizu Jun, Fujio Keishi, Amano Hirofumi, Mimori Akio, Kawakami Atsushi, Umehara Hisanori, Takeuchi Tsutomu, Sano Hajime, Muro Yoshinao, Atsumi Tatsuya, Mimura Toshihide, Kawaguchi Yasushi, Mimori Tsuneyo, Takahashi Atsushi, Kubo Michiaki, Kohsaka Hitoshi, Sumida Takayuki, Yamamoto Kazuhiko

ANNALS OF THE RHEUMATIC DISEASES   Vol. 77 ( 4 ) page： 602 - 611   2018.4

Novel potential photodynamic therapy strategy using 5-Aminolevulinic acid for ovarian clear-cell carcinoma

Teshigawara Toshiya, Mizuno Mika, Ishii Takuya, Kitajima Yuya, Utsumi Fumi, Sakata Jun, Kajiyama Hiroaki, Shibata Kiyosumi, Ishizuka Masahiro, Kikkawa Fumitaka

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY   Vol. 21   page： 121 - 127   2018.3

Glioblastoma Cell Lines Display Different Sensitivities to Plasma-Activated Medium

Tanaka Hiromasa, Mizuno Masaaki, Ishikawa Kenji, Takeda Keigo, Hashizume Hiroshi, Nakamura Kae, Utsumi Fumi, Kajiyama Hiroaki, Okazaki Yasumasa, Toyokuni Shinya, Akiyama Shinichi, Maruyama Shoichi, Kikkawa Fumitaka, Hori Masaru

IEEE TRANSACTIONS ON RADIATION AND PLASMA MEDICAL SCIENCES   Vol. 2 ( 2 ) page： 99 - 102   2018.3

Secondary cytoreductive surgery potentially improves the oncological outcomes of patients with recurrent uterine sarcomas

Nakamura Kenichi, Kajiyama Hiroaki, Utsumi Fumi, Suzuki Shiro, Niimi Kaoru, Sekiya Ryuichiro, Sakata Jun, Yamamoto Eiko, Shibata Kiyosumi, Kikkawa Fumitaka

MOLECULAR AND CLINICAL ONCOLOGY   Vol. 8 ( 3 ) page： 499 - 503   2018.3

A post-recurrence survival-predicting indicator for cervical cancer from the analysis of 165 patients who developed recurrence.

Yoshida K, Kajiyama H, Utsumi F, Niimi K, Sakata J, Suzuki S, Shibata K, Kikkawa F

Molecular and clinical oncology   Vol. 8 ( 2 ) page： 281 - 285   2018.2

The possible existence of occult metastasis in patients with ovarian clear-cell carcinoma who underwent complete resection without any residual tumours.

Kajiyama H, Suzuki S, Yoshihara M, Nishino K, Yoshikawa N, Utsumi F, Niimi K, Mizuno M, Kawai M, Oguchi H, Mizuno K, Yamamuro O, Nagasaka T, Shibata K, Kikkawa F

Oncotarget   Vol. 9 ( 5 ) page： 6298 - 6307   2018.1

A novel mechanism of neovascularization in peritoneal dissemination via cancer-associated mesothelial cells affected by TGF-beta derived from ovarian cancer

Fujikake Kayo, Kajiyama Hiroaki, Yoshihara Masato, Nishino Kimihiro, Yoshikawa Nobuhisa, Utsumi Fumi, Suzuki Shiro, Niimi Kaoru, Sakata Jun, Mitsui Hiroko, Shibata Kiyosumi, Senga Takeshi, Kikawa Fumitaka

ONCOLOGY REPORTS   Vol. 39 ( 1 ) page： 193-200   2018.1

Efficacy of medroxyprogesterone acetate treatment and retreatment for atypical endometrial hyperplasia and endometrial cancer

Tamauchi Satoshi, Kajiyama Hiroaki, Utsumi Fumi, Suzuki Shiro, Niimi Kaoru, Sakata Jun, Mizuno Mika, Shibata Kiyosumi, Kikkawa Fumitaka

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH   Vol. 44 ( 1 ) page： 151 - 156   2018.1

Carcinoma-associated mesothelial cells promote dissemination and platinum resistance in epithelial ovarian cancer.

Yoshihara Masato, Kajiyama Hiroaki, Sugiyama Mai, Yasui Hiroaki, Koya Yoshihiro, Yamakita Yoshihiko, Ryu Buntei, Yokoi Akira, Yamamoto Yusuke, Kikkawa Fumitaka

CANCER SCIENCE   Vol. 109   page： 118 - 118   2018.1

HS1 contributes cell migration/invasion and tumor formation in ovarian carcinoma

Koya Yoshihiro, Liu Wenting, Yamakita Yoshihiko, Kajiyama Hiroaki, Senga Takeshi, Shibata Kiyosumi, Nawa Akihiro, Kikkawa Fumitaka

CANCER SCIENCE   Vol. 109   page： 308 - 308   2018.1

The impact of chemokine in the peritoneal metastatic niche composed of ovarian cancer and peritoneal mesothelial cells

Yasui Hiroaki, Kajiyama Hiroaki, Yoshihara Masato, Sugiyama Mai, Kikkawa Fumitaka

CANCER SCIENCE   Vol. 109   page： 1013 - 1013   2018.1

Notch signaling enhances the mutual association with epithelial ovarian cancer and mesothelial cells

Sugiyama Mai, Kajiyama Hiroaki, Yoshihara Masato, Yasui Hiroaki, Ryu Buntei, Koya Yoshihiro, Ymakita Yoshihiko, Kikkawa Fumitaka

CANCER SCIENCE   Vol. 109   page： 1043 - 1043   2018.1

Malignant extracellular vesicles carrying MMP1 mRNA facilitate peritoneal dissemination in ovarian cancer

Yokoi Akira, Yoshioka Yusuke, Yamamoto Yusuke, Ishikawa Mitsuya, Kato Tomoyasu, Kiyono Tohru, Kajiyama Hiroaki, Kikkawa Fumitaka, Ochiya Takahiro

CANCER SCIENCE   Vol. 109   page： 29 - 29   2018.1

HS1 immunoreactivity indicates increased risk of poor overall survival in ovarian carcinoma

Liu Wenting, Kajiyama Hiroaki, Shibata Kiyosumi, Koya Yoshihiro, Senga Takeshi, Kikkawa Fumitaka

CANCER SCIENCE   Vol. 109   page： 307 - 307   2018.1

Association of serum asymmetric dimethylarginine, homocysteine, and L-arginine concentrations during early pregnancy with hypertensive disorders of pregnancy

Maruta Ei, Wang Jingwen, Kotani Tomomi, Tsuda Hiroyuki, Nakano Tomoko, Imai Kenji, Sumigama Seiji, Niwa Yoshimitsu, Mitsui Takashi, Yoshida Shigeru, Yamashita Mamoru, Nawa Akihiro, Tamakoshi Koji, Kajiyama Hiroaki, Kikkawa Fumitaka

CLINICA CHIMICA ACTA   Vol. 475   page： 70 - 77   2017.12

Inhibition of ZEB1 leads to inversion of metastatic characteristics and restoration of paclitaxel sensitivity of chronic chemoresistant ovarian carcinoma cells

Sakata Jun, Utsumi Fumi, Suzuki Shiro, Niimi Kaoru, Yamamoto Eiko, Shibata Kiyosumi, Senga Takeshi, Kikkawa Fumitaka, Kajiyama Hiroaki

ONCOTARGET   Vol. 8 ( 59 ) page： 99482 - 99494   2017.11

ALTERATION OF THE TUMOR MICROENVIRONMENT BY NOTCH SINGNALING ENHANCES THE MUTUAL ASSOCIATION WITH EPITHELIAL OVARIAN CANCER AND MESOTHELIAL CALLS

Yoshihara M., Kajiyama H., Sugiyama M., Kikkawa F.

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER   Vol. 27   page： 1726-1726   2017.11

ALTERATION OF THE TUMOR MICROENVIRONMENT BY NOTCH SINGNALING ENHANCES THE MUTUAL ASSOCIATION WITH EPITHELIAL OVARIAN CANCER AND MESOTHELIAL CALLS

Yoshihara M., Kajiyama H., Sugiyama M., Kikkawa F.

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER   Vol. 27   page： 563 - 563   2017.11

EVALUATING THE LONG TERM PROGNOSTIC FACTOR AND THE ROLE OF CYTOREDUCTION IN THE OVERALL POPULATION OF PATIENTS WITH CLINICAL AND SURGICAL STAGE IV ENDOMETRIAL CARCINOMA

Shimizu Y., Kajiyama H., Suzuki S., Yoshikawa N., Nakamura K., Yoshihara M., Tamauchi S., Yoshida K., Kikkawa F.

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER   Vol. 27   page： 1213 - 1213   2017.11

ESTABLISHMENT AND CHARACTERISATION OF PATIENT-DERIVED XENOGRAFT MODELS FOR MALIGNANT GYNECOLOGIC TUMORS

Suzuki S., Tamauchi S., Shimizu Y., Yoshihara M., Nakamura K., Yoshikawa N., Kajiyama H., Kikkawa F.

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER   Vol. 27   page： 1382 - 1382   2017.11

ESTABLISHMENT AND CHARACTERISATION OF PATIENT-DERIVED XENOGRAFT MODELS FOR MALIGNANT GYNECOLOGIC TUMORS

Suzuki S., Tamauchi S., Shimizu Y., Yoshihara M., Nakamura K., Yoshikawa N., Kajiyama H., Kikkawa F.

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER   Vol. 27   page： 494 - 494   2017.11

PELVIC EXENTERATION IN PATIENTS WITH RECURRENT OR ADVANCED GYNECOLOGIC MALIGNANCIES

Takuto N., Shimizu Y., Yoshihara M., Nakamura K., Yoshikawa N., Suzuki S., Kajiyama H., Kikkawa F.

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER   Vol. 27   page： 896 - 896   2017.11

PRIMA-1MET INDUCES APOPTOSIS THROUGH ACCUMULATION OF INTRACELLULAR REACTIVE OXYGEN SPECIES IRRESPECTIVE OF P53 STATUS AND CHEMO-SENSITIVITY IN EPITHELIAL OVARIAN CANCER CELLS

Yoshikawa N., Shimizu Y., Yoshihara M., Nakamura K., Suzuki S., Kajiyama H., Kikkawa F.

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER   Vol. 27   page： 324 - 324   2017.11

PRIMA-1MET INDUCES APOPTOSIS THROUGH ACCUMULATION OF INTRACELLULAR REACTIVE OXYGEN SPECIES IRRESPECTIVE OF P53 STATUS AND CHEMO-SENSITIVITY IN EPITHELIAL OVARIAN CANCER CELLS

Yoshikawa N., Shimizu Y., Yoshihara M., Nakamura K., Suzuki S., Kajiyama H., Kikkawa F.

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER   Vol. 27   page： 84 - 84   2017.11

A combination of circulating miRNAs for the early detection of ovarian cancer

Yokoi Akira, Yoshioka Yusuke, Hirakawa Akihiro, Yamamoto Yusuke, Ishikawa Mitsuya, Ikeda Shun-ichi, Kato Tomoyasu, Niimi Kaoru, Kajiyama Hiroaki, Kikkawa Fumitaka, Ochiya Takahiro

ONCOTARGET   Vol. 8 ( 52 ) page： 89811 - 89823   2017.10

Crystallization of calcium oxalate dihydrate in a buffered calcium-containing glucose solution by irradiation with non-equilibrium atmospheric pressure plasma

Kurake Naoyuki, Tanaka Hiromasa, Ishikawa Kenji, Nakamura Kae, Kajiyama Hiroaki, Kikkawa Fumitaka, Mizuno Masaaki, Ikehara Yuzuru, Hori Masaru

JOURNAL OF APPLIED PHYSICS   Vol. 122 ( 14 )   2017.10

Impact of positive ZEB1 expression in patients with epithelial ovarian carcinoma as an oncologic outcome-predicting indicator

Sakata Jun, Kajiyama Hiroaki, Suzuki Shiro, Utsumi Fumi, Niimi Kaoru, Sekiya Ryuichiro, Shibata Kiyosumi, Senga Takeshi, Kikkawa Fumitaka

ONCOLOGY LETTERS   Vol. 14 ( 4 ) page： 4287 - 4293   2017.10

Establishment and characterization of cell lines derived from complete hydatidiform mole

Yamamoto Eiko, Niimi Kaoru, Kiyono Tohru, Yamamoto Toshimichi, Nishino Kimihiro, Nakamura Kenichi, Kotani Tomomi, Kajiyama Hiroaki, Shibata Kiyosumi, Kikkawa Fumitaka

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE   Vol. 40 ( 3 ) page： 614 - 622   2017.9

Novel Intraperitoneal Treatment With Non-Thermal Plasma-Activated Medium Inhibits Metastatic Potential of Ovarian Cancer Cells

Nakamura Kae, Peng Yang, Utsumi Fumi, Tanaka Hiromasa, Mizuno Masaaki, Toyokuni Shinya, Hori Masaru, Kikkawa Fumitaka, Kajiyama Hiroaki

SCIENTIFIC REPORTS   Vol. 7 ( 1 ) page： 6085   2017.7

Intraperitoneal Administration of Plasma-Activated Medium: Proposal of a Novel Treatment Option for Peritoneal Metastasis From Gastric Cancer

Takeda Shigeomi, Yamada Suguru, Hattori Norifumi, Nakamura Kae, Tanaka Hiromasa, Kajiyama Hiroaki, Kanda Mitsuro, Kobayashi Daisuke, Tanaka Chie, Fujii Tsutomu, Fujiwara Michitaka, Mizuno Masaaki, Hori Masaru, Kodera Yasuhiro

ANNALS OF SURGICAL ONCOLOGY   Vol. 24 ( 5 ) page： 1188 - 1194   2017.5

Postoperative chemoradiation therapy using high dose cisplatin and fluorouracil for high- and intermediate-risk uterine cervical cancer

Miyauchi Rise, Itoh Yoshiyuki, Kawamura Mariko, Hirakawa Akihiro, Shibata Kiyosumi, Kajiyama Hiroaki, Nakahara Rie, Kubota Seiji, Ito Junji, Okada Tohru, Kikkawa Fumitaka, Naganawa Shinji

NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 79 ( 2 ) page： 211 - 220   2017.5

Effects of center dot OH and center dot NO radicals in the aqueous phase on H2O2 and NO2- generated in plasma-activated medium

Kurake Naoyuki, Tanaka Hiromasa, Ishikawa Kenji, Takeda Keigo, Hashizume Hiroshi, Nakamura Kae, Kajiyama Hiroaki, Kondo Takashi, Kikkawa Fumitaka, Mizuno Masaaki, Hori Masaru

JOURNAL OF PHYSICS D-APPLIED PHYSICS   Vol. 50 ( 15 )   2017.3

Malignant extracellular vesicles carrying MMP1 mRNA facilitate peritoneal dissemination in ovarian cancer

Yokoi Akira, Yoshioka Yusuke, Yamamoto Yusuke, Ishikawa Mitsuya, Ikeda Shun-ichi, Kato Tomoyasu, Kiyono Tohru, Takeshita Fumitaka, Kajiyama Hiroaki, Kikkawa Fumitaka, Ochiya Takahiro

NATURE COMMUNICATIONS   Vol. 8   page： 14470   2017.3

Clinical significance and predicting indicators of post-cancer-treatment survival in terminally ill patients with ovarian cancer

Utsumi Fumi, Kajiyama Hiroaki, Niimi Kaoru, Sekiya Ryuichiro, Sakata Jun, Suzuki Shiro, Shibata Kiyosumi, Mizuno Mika, Kikkawa Fumitaka

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH   Vol. 43 ( 2 ) page： 365 - 370   2017.2

Future perspective of strategic non-thermal plasma therapy for cancer treatment

Kajiyama Hiroaki, Utsumi Fumi, Nakamura Kae, Tanaka Hiromasa, Toyokuni Shinya, Hori Masaru, Kikkawa Fumitaka

JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION   Vol. 60 ( 1 ) page： 33 - 38   2017.1

c-Rel Promotes Invasion of Choriocarcinoma Cells via PI3K/AKT Signaling

Sekiya Yoko, Yamamoto Eiko, Niimi Kaoru, Nishino Kimihiro, Nakamura Kenichi, Kotani Tomomi, Kajiyama Hiroaki, Shibata Kiyosumi, Kikkawa Fumitaka

ONCOLOGY   Vol. 92 ( 5 ) page： 299 - 310   2017

A recurrence-predicting prognostic factor for patients with ovarian clear-cell adenocarcinoma at reproductive age. Reviewed

Kajiyama H, Mizuno M, Shibata K, Umezu T, Suzuki S, Yamamoto E, Mitsui H, Sekiya R, Niimi K, Kawai M, Nagasaka T, Kikkawa F.

Int J Clin Oncol.   Vol. 19 ( 5 ) page： 921-7   2014.10

Oncologic outcome after recurrence in patients with stage I epithelial ovarian cancer: are clear-cell and mucinous histological types a different entities? Reviewed

Kajiyama H, Mizuno M, Shibata K, Umezu T, Suzuki S, Yamamoto E, Mitsui H, Sekiya R, Niimi K, Kawai M, Nagasaka T, Kikkawa F.

Eur J Obstet Gynecol Reprod Biol.   Vol. 181   page： 305-10   2014.10

PLAGL2 regulates actin cytoskeletal architecture and cell migration. Reviewed

Sekiya R, Maeda M, Yuan H, Asano E, Hyodo T, Hasegawa H, Ito S, Shibata K, Hamaguchi M, Kikkawa F, Kajiyama H, Senga T.

Carcinogenesis.     2014.9

Expression of the miR200 family of microRNAs in mesothelial cells suppresses the dissemination of ovarian cancer cells. Reviewed

Expression of the miR200 family of microRNAs in mesothelial cells suppresses the dissemination of ovarian cancer cells.

Mol Cancer Ther.   Vol. 13 ( 8 ) page： 2081-91   2014.8

Selective cytotoxicity of indirect nonequilibrium atmospheric pressure plasma against ovarian clear-cell carcinoma. Reviewed

Utsumi F, Kajiyama H, Nakamura K, Tanaka H, Hori M, Kikkawa F.

Springerplus.     page： 10.1186/2193-1801-3-398   2014.7

Recurrence-predicting prognostic factors for patients with early-stage epithelial ovarian cancer undergoing fertility-sparing surgery: a multi-institutional study. Reviewed

Kajiyama H, Mizuno M, Shibata K, Yamamoto E, Kawai M, Nagasaka T, Kikkawa F.

Eur J Obstet Gynecol Reprod Biol.     page： 10.1016/j.ejogrb.2014.01.014.   2014.4

Survival benefit of taxane plus platinum in recurrent ovarian cancer with non-clear cell, non-mucinous histology. Reviewed

Kajiyama H, Shibata K, Mizuno M, Umezu T, Suzuki S, Sekiya R, Niimi K, Mitsui H, Yamamoto E, Kawai M, Nagasaka T, Kikkawa F.

J Gynecol Oncol.   Vol. 25 ( 1 ) page： 43-50   2014.4

Is there any association between where patients spend the end of life and survival after anticancer treatment for gynecologic malignancy? Reviewed

Kajiyama H, Utsumi F, Higashi M, Sakata J, Sekiya R, Mizuno M, Umezu T, Suzuki S, Yamamoto E, Mitsui H, Niimi K, Shibata K, Kikkawa F.

J Palliat Med.   Vol. 17 ( 3 ) page： 325-30   2014.3

Effect of indirect nonequilibrium atmospheric pressure plasma on anti-proliferative activity against chronic chemo-resistant ovarian cancer cells in vitro and in vivo. Reviewed

Utsumi F, Kajiyama H, Nakamura K, Tanaka H, Mizuno M, Ishikawa K, Kondo H, Kano H, Hori M, Kikkawa F.

PLoS One.     page： 10.1371/journal.pone.0081576.   2013.12

Long-term clinical outcome of patients with recurrent epithelial ovarian carcinoma: is it the same for each histological type? Reviewed

  Vol. 22 ( 3 ) page： 394-9   2012.3

Postrecurrent oncologic outcome of patients with ovarian clear cell carcinoma. Reviewed

Kajiyama H, Shibata K, Mizuno M, Yamamoto E, Fujiwara S, Umezu T, Suzuki S, Nakanishi T, Nagasaka T, Kikkawa F.

Int J Gynecol Cancer.     page： 10.1097/IGC.0b013e3182540145.   2012

Expression of Twist enhances risk of poor oncologic outcome in patients with stage Ib to II cervical carcinoma with lymphovascular space involvement. Reviewed

    page： doi:pii: S0046-8177(12)00190-6   2012

Long-term survival of young women receiving fertility-sparing surgery for ovarian cancer in comparison with those undergoing radical surgery. Reviewed

Kajiyama H, Shibata K, Mizuno M, Umezu T, Suzuki S, Nawa A, Kawai M, Nagasaka T, Kikkawa F.

Br J Cancer   Vol. 105 ( 9 ) page： 1288-94   2011.11

*Fertility-sparing surgery in young women with invasive epithelial ovarian cancer. Reviewed

Kajiyama H, Shibata K, Suzuki S, Ino K, Nawa A, Kawai M, Nagasaka T, Kikkawa F.

Eur J Surg Oncol. 2010   Vol. in press   2010

Fertility-sparing surgery in young women with invasive epithelial ovarian cancer. Reviewed

Kajiyama H, Shibata K, Suzuki S, Ino K, Nawa A, Kawai M, Nagasaka T, KikkawaF.

Eur J Surg Oncol.   Vol. 36 ( 4 ) page： 404-8   2010

The expression ofdipeptidyl peptidase IV (DPPIV/CD26) is associated with enhanced chemosensitivity to paclitaxel in epithelial ovarian carcinoma cells. Reviewed

Kajiyama H, Shibata K, Ino K, Mizutani S, Nawa A, Kikkawa F

Cancer Sci.   Vol. 101 ( 2 ) page： 347-54   2010

The expression of dipeptidyl peptidase IV (DPPIV/CD26) is associated with enhanced chemosensitivity to paclitaxel in epithelial ovarian carcinoma cells. Reviewed

Kajiyama H, Shibata K, Ino K, Mizutani S, Nawa A, Kikkawa F.

Cancer Sci. 2009   Vol. in press   2009

Development of "super-bio-functions" by plasma-activated biological substances

Grant number：19H05462  2019.4 - 2024.3

Grants-in-Aid for Scientific Research  Grant-in-Aid for Specially Promoted Research

Elucidation of malignancy, peritoneal dissemination and spread mechanism of ovarian cancer by interaction with peritoneal mesothelium.

Grant number：19H03797  2019.4 - 2022.3

Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)

Interdisciplinary research on intraperitoneal cell-to-cell crosstalk focusing ovarian cancer-associated mesothelial cells

Grant number：17H04338  2017.4 - 2020.3

Kajiyama Hiroaki

Analysis of tumor-infiltrating lymphocytes in malignant gynecologic tumors for development of personalized tumor immunotherapy

Grant number：16H05472  2016.4 - 2019.3

Kikkawa Fumitaka

Elucidation of peritoneal dissemination mechanism by exosome from ovarian cancer and development of new treatment

Grant number：16K15704  2016.4 - 2018.3

Kikkawa Fumitaka

Interdisciplinary study of obstetric management and gynecological rare tumor in Vietnam

Grant number：15H02660  2015.4 - 2020.3

FUMITAKA KIKKAWA

The development of tailor-made immunotherapy based on ovarian cancer local immunity analysis

Grant number：15K10714  2015.4 - 2018.3

Shibata Kiyoisumi

Photodynamic diagnosis of ovarian cancer by 5-aminolevulinic acid and establishment of novel treatment

Grant number：15K10713  2015.4 - 2018.3

Mika Mizuno

EMTを標的とする、微少環境ストレス誘導転移の解明と克服～卵巣癌の予後向上へ～

2012.4

科学研究費補助金  基盤研究(B)

難治性卵巣癌における上皮間葉転換に基づくオンコジェニック ストレス耐性のメカニズム

2009 - 2012

科学研究費補助金  若手研究Ａ

梶山広明

上皮間葉転換に基づく細胞膜型ペプチド分解酵素を分子標的とした卵巣癌腹膜転移の抑制

2006.4 - 2009.3

科学研究費補助金  若手研究(A)