専門医制度委員会   産業専門医・指導医

2017.2

分子予防環境医学研究会

第5回花王研究奨励賞　医学・生物学分野

2003.6   花王芸術・科学財団  

H14年度　安江賞

2002   東海皮膚科漢方研究会  

Just 1-min exposure to a pure tone at 100 Hz with daily exposable sound pressure levels may improve motion sickness. Invited Reviewed Open Access

Gu Y, Ohgami N, He T, Kagawa T, Kurniasari F, Tong K, Li X, Tazaki A, Takeda K, Mouri M, Kato M

Environ Health Prev Med in press   Vol. 30   page： 22   2025

Anti-Graying Effects of External and Internal Treatments with Luteolin on Hair in Model Mice Reviewed

Iida, M; Kagawa, T; Yajima, I; Harusato, A; Tazaki, A; Nishadhi, DASM; Taguchi, N; Kato, M

ANTIOXIDANTS   Vol. 13 ( 12 )   2024.12

Progression from in vivo validation to in vitro screening in hazard assessment for leukoderma-inducible chemicals Reviewed

Tazaki, A; Nishadhi, DASM; Li, A; Zhang, LY; Maw, TH; Kondo-Ida, L; Yanagisawa, K; Kato, M

ENVIRONMENTAL POLLUTION   Vol. 356   page： 124508   2024.9

Elevated level of urinary tellurium is a potential risk for increase of blood pressure in humans and mice. Invited Reviewed

Kurniasari F, Htike Maw Than, Tazaki A, Kagawa T, Al Hossain M.M.A, Akhand AA, Ahsan N, Ohnuma S, Iwasaki N, Kato M.

Environment international   Vol. 188 ( 108735 ) page： 108735   2024.6

Efficacy of 100 hz sound stimulation on saccular dysfunction in meniere's disease Reviewed

Sone, M; Ohgami, N; Katayama, N; Kobayashi, M; Gu, Y; Tong, K; Yoshida, T; Naganawa, S; Kato, M

ACTA OTO-LARYNGOLOGICA   Vol. 144 ( 4 ) page： 272 - 276   2024.4

Upregulation of IL4-induced gene 1 enzyme by B2 cells during melanoma progression impairs their antitumor properties Reviewed

Bekkat, F; Seradj, M; Lengagne, R; Fiore, F; Kato, M; Lucas, B; Castellano, F; Molinier-Frenkel, V; Richard, Y; Prevost-Blondel, A

EUROPEAN JOURNAL OF IMMUNOLOGY   Vol. 54 ( 4 ) page： e2350615   2024.4

Beneficial and adverse effects of dam construction in canal tannery wastewater effluent with a high content of chromium in Hazaribagh, Bangladesh. Reviewed

Kurniasari F, Htike MT, Tazaki A, Kagawa T, Al Hossain MMA, Akhand AA, Ahsan N, Ohnuma S, Iwasaki N, Kato M

Chemosphere   Vol. 350   page： 141047   2024.2

Retinal ferroptosis as a critical mechanism for the induction of retinochoroiditis during ocular toxoplasmosis Reviewed

Yamada, K; Tazaki, A; Ushio-Watanabe, N; Usui, Y; Takeda, A; Matsunaga, M; Suzumura, A; Shimizu, H; Zheng, H; Ariefta, NR; Yamamoto, M; Hara, H; Goto, H; Sonoda, KH; Nishiguchi, KM; Kato, M; Nishikawa, Y; Toyokuni, S; Kaneko, H

REDOX BIOLOGY   Vol. 67   page： 102890   2023.11

Unexpected associations of long-term and excessive exposure to trivalent chromium with hypertension and glycosuria in male tannery workers. Reviewed

Tsuchiyama T, Chen D, Al Hossain MMA, Tazaki A, Kagawa T, Gu Y, Gao Y, Kurniasari F, Ahsan N, Akhand AA, Kato M

Chemosphere   Vol. 337   page： 139190   2023.10

Elevated arsenic level in fasting serum via ingestion of fish meat increased the risk of hypertension in humans and mice Open Access

Kagawa, T; Ohgami, N; He, T; Tazaki, A; Ohnuma, S; Naito, H; Yajima, I; Chen, D; Deng, Y; Tamura, T; Kondo, T; Wakai, K; Kato, M

EUROPEAN HEART JOURNAL OPEN   Vol. 3 ( 5 ) page： oead074   2023.9

Efficient removal of molybdate from groundwater with visible color changes using wasted aerobic granular sludge. Invited Reviewed

Tian Yuan, Jing Xu, Zhiwei Wang, Zhongfang Lei, Masashi Kato, Kazuya Shimizu, Zhenya Zhang

Separation and Purification Technology   Vol. 317   2023.7

Actin crosslinking by α-actinin averts viscous dissipation of myosin force transmission in stress fibers

Katsuta, H; Okuda, S; Nagayama, K; Machiyama, H; Kidoaki, S; Kato, M; Sokabe, M; Miyata, T; Hirata, H

ISCIENCE   Vol. 26 ( 3 ) page： 106090   2023.3

Zinc deficiency is associated with the development of ovarian endometrial cysts

Onuma Toshimichi, Mizutani Tetsuya, Fujita Yuko, Ohgami Nobutaka, Ohnuma Shoko, Kato Masashi, Yoshida Yoshio

AMERICAN JOURNAL OF CANCER RESEARCH   Vol. 13 ( 3 ) page： 1049 - 1066   2023

Zinc deficiency is associated with the development of ovarian endometrial cysts.

Onuma T, Mizutani T, Fujita Y, Ohgami N, Ohnuma S, Kato M, Yoshida Y

American journal of cancer research   Vol. 13 ( 3 ) page： 1049 - 1066   2023

Vascular endothelium as a target tissue for short-term exposure to low-frequency noise that increases cutaneous blood flow

Deng, Y; Ohgami, N; Kagawa, T; Kurniasari, F; Chena, D; Kato, M; Tazaki, A; Aoki, M; Katsuta, H; Tong, K; Gu, Y; Kato, M

SCIENCE OF THE TOTAL ENVIRONMENT   Vol. 851 ( Pt 1 ) page： 158828   2022.12

Potential application of a hydrotalcite-like compound for reduction of toxicity to aquatic organisms via rapid and efficient removal of hydrogen sulfide

Yuan, T; Hashimoto, K; Tazaki, A; Hasegawa, M; Kurniasari, F; Ohta, C; Aoki, M; Ohgami, N; Kato, M

JOURNAL OF ENVIRONMENTAL MANAGEMENT   Vol. 321   page： 115861   2022.11

Decreased hearing levels at frequencies for understanding speech in tannery workers exposed to a high level of trivalent chromium in Bangladesh

Gu, YS; Ohgami, N; Hossain, MMAA; Tazaki, A; Tsuchiyama, T; He, TC; Aoki, M; Ahsan, N; Akhand, AA; Kato, M

CHEMOSPHERE   Vol. 306   page： 135571   2022.11

Redistribution of potentially toxic elements in the hydrosphere after the relocation of a group of tanneries Reviewed

Kurniasari F, Tazaki A, Hashimoto K, Yuan T, Al Hossain MMA, Akhand AA, Ahsan N, Ohnuma S, Kato M.

Chemosphere   Vol. 303 ( 2 ) page： 135098 - 135107   2022.9

Significance of platinum distribution to predict platinum resistance in ovarian cancer after platinum treatment in neoadjuvant chemotherapy

Uno, K; Yoshikawa, N; Tazaki, A; Ohnuma, S; Kitami, K; Iyoshi, S; Mogi, K; Yoshihara, M; Koya, Y; Sugiyama, M; Tamauchi, S; Ikeda, Y; Yokoi, A; Kikkawa, F; Kato, M; Kajiyama, H

SCIENTIFIC REPORTS   Vol. 12 ( 1 ) page： 4513   2022.3

Calcitriol inhibits arsenic-promoted tumorigenesis through regulation of arsenic-uptake in a human keratinocyte cell line Reviewed

Yajima I, Tazaki A, Ohgami N, Kato M.

American Journal of Cancer Research   Vol. 12 ( 11 ) page： 5019 - 5028   2022

Calcitriol inhibits arsenic-promoted tumorigenesis through regulation of arsenic-uptake in a human keratinocyte cell line.

Yajima I, Tazaki A, Ohgami N, Kato M

American journal of cancer research   Vol. 12 ( 11 ) page： 5019 - 5028   2022

Calcitriol inhibits arsenic-promoted tumorigenesis through regulation of arsenic-uptake in a human keratinocyte cell line

Yajima Ichiro, Tazaki Akira, Ohgami Nobutaka, Kato Masashi

AMERICAN JOURNAL OF CANCER RESEARCH   Vol. 12 ( 11 ) page： 5019 - +   2022

Development of an efficient remediation system with a low cost after identification of water pollutants including phenolic compounds in a tannery built-up area in Bangladesh

Yuan, T; Tazaki, A; Hashimoto, K; Al Hossain, MMA; Kurniasari, F; Ohgami, N; Aoki, M; Ahsan, N; Akhand, AA; Kato, M

CHEMOSPHERE   Vol. 280   page： 130959   2021.10

Reply Invited Reviewed

Takumi Kagawa, Akira Tazaki , Huadong Xu, Nobutaka Ohgami, Masashi Kato

J Allergy Clin Immunol   Vol. 148 ( 2 ) page： 655 - 656   2021.8

Intranasal levels of lead as an exacerbation factor for allergic rhinitis in humans and mice

Xu, HD; Ohgami, N; Sakashita, M; Ogi, K; Hashimoto, K; Tazaki, A; Tong, KM; Aoki, M; Fujieda, S; Kato, M

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY   Vol. 148 ( 1 ) page： 139 - +   2021.7

Intranasal levels of lead as an exacerbation factor for allergic rhinitis in humans and mice. Reviewed

Xu H, Ohgami N, Sakashita M, Ogi K, Hashimoto K, Tazaki A, Tong K, Aoki M, Fujieda S, Kato M

The Journal of Allergy and Clinical Immunology     page： in press   2021.3

Loss-of-function mutation of c-Ret causes cerebellar hypoplasia in mice with Hirschsprung disease and Down's syndrome Reviewed

Ohgami N, Iizuka A, Hirai H, Yajima I, Iida M, Shimada A, Tsuzuki T, Jijiwa M, Asai N, Takahashi M, Kato M

Journal of Biological Chemistry   Vol. 296   page： 100389   2021.1

Development of an efficient remediation system with a low cost after identification of water pollutants including phenolic compounds in a tannery built-up area in Bangladesh. Reviewed

Yuan T, Tazaki A, Hashimoto K, Al Hossain MMA, Kurniasaria F, Ohgamia N, Aoki M, Ahsand N, Akhand AA, Kato M

Chemosphere     2021

Lithium promotes malignant transformation of nontumorigenic cells in vitro. Reviewed

Sudo M, Hashimoto K, Yoshinaga M, Azimi MD, Fayaz SH, Hamajima N, Kondo-Ida L, Yanagisawa K, Kato M

The Science of the total environment   Vol. 744   page： 140830   2020.11

High levels of boron promote anchorage-independent growth of nontumorigenic cells.

Xu H, Hashimoto K, Maeda M, Azimi MD, Fayaz SH, Chen W, Hamajima N, Kato M

Environmental pollution (Barking, Essex : 1987)   Vol. 266 ( Pt 3 ) page： 115094   2020.11

Hair graying with aging in mice carrying oncogenic <i>RET</i>

Iida, M; Tazaki, A; Yajima, I; Ohgami, N; Taguchi, N; Goto, Y; Kumasaka, MY; Prévost-Blondel, A; Kono, M; Akiyama, M; Takahashi, M; Kato, M

AGING CELL   Vol. 19 ( 11 ) page： e13273   2020.11

Increased levels of renal damage biomarkers caused by excess exposure to trivalent chromium in workers in tanneries.

Tsuchiyama T, Tazaki A, Al Hossain MA, Yajima I, Ahsan N, Akhand AA, Hashimoto K, Ohgami N, Kato M

Environmental research   Vol. 188   page： 109770   2020.9

Application of a human mesoderm tissue elongation system <i>in vitro</i> derived from human induced pluripotent stem cells to risk assessment for teratogenic chemicals

Ninomiya, H; Intoh, A; Ishimine, H; Onuma, Y; Ito, Y; Michiue, T; Tazaki, A; Kato, M

CHEMOSPHERE   Vol. 250   page： 126124   2020.7

Multidisciplinary approach to assess the toxicities of arsenic and barium in drinking water Reviewed

Kato Masashi, Ohgami Nobutaka, Ohnuma Shoko, Hashimoto Kazunori, Tazaki Akira, Xu Huadong, Kondo-Ida Lisa, Yuan Tian, Tsuchiyama Tomoyuki, He Tingchao, Kurniasari Fitri, Gu Yishuo, Chen Wei, Deng Yuqi, Komuro Kanako, Tong Keming, Yajima Ichiro

ENVIRONMENTAL HEALTH AND PREVENTIVE MEDICINE   Vol. 25 ( 1 ) page： 16   2020.5

A new method with an explant culture of the utricle for assessing the influence of exposure to low-frequency noise on the vestibule Reviewed

Ohgami Nobutaka, He Tingchao, Oshino-Negishi Reina, Gu Yishuo, Li Xiang, Kato Masashi

JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES   Vol. 83 ( 5 ) page： 215 - 218   2020.3

Peptides containing the MXXCW motif inhibit oncogenic RET kinase activity with a novel mechanism of action Reviewed

Takeda Kozue, Kawamoto Yoshiyuki, Nagasaki Yosuke, Okuno Yusuke, Goto Yuko, Iida Machiko, Yajima Ichiro, Ohgami Nobutaka, Kato Masashi

AMERICAN JOURNAL OF CANCER RESEARCH   Vol. 10 ( 1 ) page： 336 - 349   2020

Hair graying with aging in mice carrying oncogenic RET Reviewed

Iida M, Tazaki A, Yajima I, Ohgami N, Taguchi N, Goto Y, Kumasaka YM, Prevost-Blondel A, Kono M, Akiyama M, Takahashi M, Kato M

Aging Cell     page： in press   2020

Peptides containing the MXXCW motif inhibit oncogenic RET kinase activity with a novel mechanism of action.

Takeda K, Kawamoto Y, Nagasaki Y, Okuno Y, Goto Y, Iida M, Yajima I, Ohgami N, Kato M

American journal of cancer research   Vol. 10 ( 1 ) page： 336 - 349   2020

A unique system that can sensitively assess the risk of chemical leukoderma by using murine tail skin

Iida Machiko, Tazaki Akira, Deng Yuqi, Chen Wei, Yajima Ichiro, Kondo-Ida Lisa, Hashimoto Kazunori, Ohgami Nobutaka, Kato Masashi

CHEMOSPHERE   Vol. 235   page： 713 - 718   2019.11

Heat shock protein 70 is a key molecule to rescue imbalance caused by low frequency noise.

Negishi-Oshino R, OhgamiN, He T, Li X, Kato M, Kobayashi M, Gu Y, Komuro K, Angelidis CE, Kato M

Archives of Toxicology   Vol. 93 ( 11 ) page： 3219 - 3228   2019.11

Histological analysis of the skin of Abca1-deleted mice: A potential model for dry skin.

Deng Y, Ohgami N, Iida M, Tazaki A, Intoh A, Kondo-Ida L, Lu R, Tuzuki T, Yokoyama S, Kato M.

European Journal of Dermatology   Vol. 29 ( 5 ) page： 549 - 551   2019.9

Chromium-mediated hyperpigmentation of skin in male tannery workers in Bangladesh

Al Hossain A MM, Yajima I, Tazaki A, Xu H, Saheduzzaman M, Ohgami N, Ahsan N, Akhand AA, Kato M

CHEMOSPHERE   Vol. 229   page： 611 - 617   2019.8

Hearing loss in humans drinking tube well water with high levels of iron in arsenic-polluted area.

He T, Ohgami N, Li X, Yajima I, Oshino R, Kato Y, Ohgami K, Xu Huadong, Ahsan N, Akhand AA, Kato M

Scientific Reports   Vol. 9 ( 1 ) page： 9028   2019.6

cVEMP correlated with imbalance in a mouse model of vestibular disorder.

Negishi-Oshino R, OhgamiN, He T, Ohgami K, Li X, Kato M

Environ Health Prev Med   Vol. 24 ( 1 ) page： 39   2019.6

Adsorption of molybdenum by melanin

Chen Wei, Hashimoto Kazunori, Omata Yasuhiro, Ohgami Nobutaka, Tazaki Akira, Deng Yuqi, Kondo-Ida Lisa, Intoh Atsushi, Kato Masashi

ENVIRONMENTAL HEALTH AND PREVENTIVE MEDICINE   Vol. 24 ( 1 ) page： 36   2019.5

Inhibition of mast cell degranulation by melanin.

Kawamoto Y, Kondo H, Hasegawa M, Kurimoto C, Ishii Y, Kato C, Botei T, Shinya M, Murate T, Ueno Y, Kawabe M, Goto Y, Yamamoto R, Iida M, Yajima I, Ohgami N, Kato M, Takeda K

Biochemical Pharmacology   Vol. 163   page： 178 - 193   2019.5

For making a declaration of countermeasures against the falling birth rate from the Japanese Society for Hygiene: summary of discussion in the working group on academic research strategy against an aging society with low birth rate.

Nomura K, Karita K, Araki A, Nishioka E, Muto G, Iwai-Shimada M, Nishikitani M, Inoue M, Tsurugano S, Kitano N, Tsuji M, Iijima S, Ueda K, Kamijima M, Yamagata Z, Sakata K, Iki M, Yanagisawa H, Kato M, Inadera H, Kokubo Y, Yokoyama K, Koizumi A, Otsuki T

Environmental Health and Preventive Medicine   Vol. 24 ( 1 ) page： 14   2019.3

[Toward a Declaration to Address Japan's Aging Society with Low Birth Rate: Summary of the Japanese Society for Hygiene's Working Group on Academic Research Strategy against an Aging Society with Low Birth Rate].

Nomura K, Karita K, Araki A, Nishioka E, Muto G, Iwai-Shimada M, Nishikitani M, Inoue M, Tsurugano S, Kitano N, Tsuji M, Iijima S, Ueda K, Kamijima M, Yamagata Z, Sakata K, Iki M, Yanagisawa H, Kato M, Yokoyama K, Koizumi A, Otsuki T

Nihon eiseigaku zasshi. Japanese journal of hygiene   Vol. 74 ( 0 )   2019

Improvement of balance in young adults by a sound component at 100Hz in music Reviewed

Huadong Xu, Nobutaka Ohgami, Tingchao He, Kazunori Hashimoto, Akira Tazaki, Kyoko Ohgami, Kozue Takeda & Masashi Kato

Scientific Report   Vol. 8 ( 1 ) page： 16894   2018.11

A disadvantageous effect of adsorption of barium by melanin on transforming activity

Omata Yasuhiro, Yoshinaga Masafumi, Yajima Ichiro, Ohgami Nobutaka, Hashimoto Kazunori, Higashimura Kaho, Tazaki Akira, Kato Masashi

CHEMOSPHERE   Vol. 210   page： 384 - 391   2018.11

Label-Free Imaging of Melanoma with Confocal Photothermal Microscopy: Differentiation between Malignant and Benign Tissue.

Kobayashi T, Nakata K, Yajima I, Kato M, Tsurui H

Bioengineering (Basel, Switzerland)   Vol. 5 ( 3 )   2018.8

Arsenic level in toenails is associated with hearing loss in humans

Li Xiang, Ohgami Nobutaka, Yajima Ichiro, Xu Huadong, Iida Machiko, Oshino Reina, Ninomiya Hiromasa, Shen Dandan, Ahsan Nazmul, Akhand Anwarul Azim, Kato Masashi

PLOS ONE   Vol. 13 ( 7 ) page： e0198743   2018.7

Increased expression level of Hsp70 in the inner ears of mice by exposure to low frequency noise

Ninomiya Hiromasa, Ohgami Nobutaka, Oshino Reina, Kato Masashi, Ohgami Kyoko, Li Xiang, Shen Dandan, Iida Machiko, Yajima Ichiro, Angelidis Charalampos E., Adachi Hiroaki, Katsuno Masahisa, Sobue Gen, Kato Masashi

HEARING RESEARCH   Vol. 363   page： 49 - 54   2018.6

A comprehensive study including monitoring, assessment of health effects and development of a remediation method for chromium pollution

Yoshinaga Masafumi, Ninomiya Hiromasa, Al Hossain M. M. Aeorangajeb, Sudo Makoto, Akhand Anwarul Azim, Ahsan Nazmul, Alim Md. Abdul, Khalequzzaman Md., Iida Machiko, Yajima Ichiro, Ohgami Nobutaka, Kato Masashi

CHEMOSPHERE   Vol. 201   page： 667 - 675   2018.6

Exposure of Mice to 1,2-Dichloropropane Induces CYP450-Dependent Proliferation and Apoptosis of Cholangiocytes

Zhang Xiao, Zong Cai, Zhang Lingyi, Garner Edwin, Sugie Shigeyuki, Huang Chinyen, Wu Wenting, Chang Jie, Sakurai Toshihiro, Kato Masashi, Ichihara Sahoko, Kumagai Shinji, Ichihara Gaku

TOXICOLOGICAL SCIENCES   Vol. 162 ( 2 ) page： 559 - 569   2018.4

Impairment of extra-high frequency auditory thresholds in subjects with elevated levels of fasting blood glucose.

Das A, Sumit AF, Ahsan N, Kato M, Ohgami N, Akhand AA

Journal of otology   Vol. 13 ( 1 ) page： 29-35   2018.3

Arsenic levels in cutaneous appendicular organs are correlated with digitally evaluated hyperpigmented skin of the forehead but not the sole in Bangladesh residents. Reviewed

Yajima I, Ahsan Nazmul, Akhand AA, Al Hossain A MM, Yoshinaga M, Ohgami N, Iida M, Oshino R, Naito M, Wakai K, Kato M.

J Expo Sci Environ Epidemiol     2018.1

Arsenic levels in cutaneous appendicular organs are correlated with digitally evaluated hyperpigmented skin of the forehead but not the sole in Bangladesh residents

Yajima, I; Ahsan, N; Akhand, AA; Al Hossain, MMA; Yoshinaga, M; Ohgami, N; Iida, M; Oshino, R; Naito, M; Wakai, K; Kato, M

JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY   Vol. 28 ( 1 ) page： 64 - 68   2018.1

Inflammation drives nitric oxide synthase 2 expression by gamma delta T cells and affects the balance between melanoma and vitiligo associated melanoma

Douguet Laetitia, Bod Lloyd, Labarthe Laura, Lengagne Renee, Kato Masashi, Couillin Isabelle, Prevost-Blondel Armelle

ONCOIMMUNOLOGY   Vol. 7 ( 9 ) page： e1484979   2018

Manganese in toenails is associated with hearing loss at high frequencies in humans

Ohgami Nobutaka, Li Xiang, Yajima Ichiro, Oshino Reina, Ohgami Kyoko, Kato Yoko, Ahsan Nazmul, Akhand Anwarul Azim, Kato Masashi

BIOMARKERS   Vol. 23 ( 6 ) page： 533 - 539   2018

Label-free imaging of melanoma with confocal photothermal microscopy: Differentiation between malignant and benign tissue. Reviewed

Kobayashi T, Nakata K, Yajima I, Kato M, Tsurui H

Bioengineering     page： in press   2018

Arsenic-mediated hyperpigmentation in skin via NF-kappa B/endothelin-1 signaling in an originally developed hairless mouse model

Yajima Ichiro, Kumasaka Mayuko Y., Iida Machiko, Oshino Reina, Tanihata Hiroko, Al Hossain Aeorangajeb, Ohgami Nobutaka, Kato Masashi

ARCHIVES OF TOXICOLOGY   Vol. 91 ( 11 ) page： 3507 - 3516   2017.11

Manganese-Mediated Decrease in Levels of c-RET and Tyrosine Hydroxylase Expression In Vitro

Kumasaka, MY; Yajima, I; Ohgami, N; Ninomiya, H; Iida, M; Li, X; Oshino, R; Tanihata, H; Yoshinaga, M; Kato, M

NEUROTOXICITY RESEARCH   Vol. 32 ( 4 ) page： 661 - 670   2017.11

Risk assessment of neonatal exposure to low frequency noise based on balance in mice. Reviewed

Ohgami N, Oshino R, Ninomiya H, Li X, Kato M, Yajima I, Kato M.

Front Behav Neurosci     2017.2

Role of cytochrome P450s in male reproductive toxicity of 1-bromopropane. Reviewed

Zong C, Zhang X, Huang C, Chang J, Garner E, Sakurai T, Kato M, Ichihara S, Ichihara G.

Toxicol Res     page： in press   2017

IL4-induced gene 1 promotes tumor growth by shaping the immune microenvironment in melanoma. Reviewed

Bod L, Lengagne R, Wrobel L, Ramspott JP, Kato M, Avril M-F, Castellano F, Molinier-Frenkel V, Prévost-Blondel A.

OncoImmunology     page： in press   2017

Manganese-mediated decrease in levels of c-RET and tyrosine hydroxylase expression in vitro.

Kumasaka MY, Yajima I, Ohgami N, Ninomiya H, Iida M, Li X, Oshino R, Tanihata H, Yoshinaga M, Kato M.

Neurotox Res     page： in press   2017

Oral exposure to arsenic causes hearing loss in young people aged 12-29 years and in young mice.

Li x, Ohgami N, Omata Y, Yajima I, Iida M, Oshino R, Ohnuma S, Ahsan N, Akhand AA, Kato M.

Sci Rep     page： in press   2017

Arsenic-mediated hyperpigmented skin via NF-kappa B/Endothelin1 signaling in an originally developed hairless mouse model.

Yajima I, Kumasaka MY, Iida M, Oshino R, Tanihata H, Al Hossain A MM, Ohgami N, Kato M.

Arch Toxicol     page： in press   2017

Amelioration of arsenic-induced toxic effects in mice by dietary supplementation of Syzygium cumini leaf extract.

Barai M, Ahsan N, Paul N, Hossain K, Rashid M, Abdur, Kato M, Ohgami N, Akhad AA.

Nagoya J Med Sci     page： in press   2017

Exposure to diphtheria toxin during the juvenile period impairs both inner and outer hair cells in C57BL/6 mice.

Konishi H, Ohgami N, Matsushita A, Kondo Y, Aoyama Y, Kobayashi M, Nagai T, Ugawa S, Yamada K, Kato M, Kiyama H.

Neuroscience     page： in press   2017

Impairments of Inner Ears Caused by Physical Environmental Stresses.

Ohgami N, Oshino R, Ninomiya H, Li X, Kato M

Nihon eiseigaku zasshi. Japanese journal of hygiene   Vol. 72 ( 1 ) page： 38 - 42   2017

IL4-induced gene 1 promotes tumor growth by shaping the immune microenvironment in melanoma

Bod, L; Lengagne, E; Wrobel, L; Ramspott, JP; Kato, M; Avril, MF; Castellano, F; Molinier-Frenkel, V; Prevost-Blondel, A

ONCOIMMUNOLOGY   Vol. 6 ( 3 ) page： e1278331   2017

Uranium in well drinking water of Kabul, Afghanistan and its effective, low-cost depuration using Mg-Fe based hydrotalcite-like compounds. Reviewed

Kato M, Azimi MD, Fayaz SH, Shah MD, Hoque MZ, Hamajima N, Ohnuma S, Ohtsuka T, Maeda M, Yoshinaga M.

Chemosphere   Vol. 165   page： 27-32   2016.12

Limited effectiveness of household sand filters for removal of arsenic from well water in North Vietnam. Reviewed

Ilmiawati C, Thang ND, Iida M, Maeda M, Ohnuma S, Yajima I, Ohgami N, Oshino R, Al Hossain A MM, Hiromasa N, Kato M.

J Water Health   Vol. 14 ( 6 ) page： 1032-1040   2016.12

Manganese-mediated acceleration of age-related hearing loss in mice. Reviewed

Ohgami N, Yajima I, Iida M, Li X, Oshino R, Kumasaka YM, Kato M.

Sci Rep   Vol. 8 ( 6 ) page： 36306   2016.11

Propranolol induces a favourable shift of anti-tumor immunity in a murine spontaneous model of melanoma. Reviewed

Wrobel LJ, Bod L, Lengagne R, Kato M, Prévost- Blondel A, Gal1 FL.

Oncotarget   Vol. 7 ( 47 ) page： 77825-77837   2016.11

Response to the letter to the editor: Metallothionein MT2A A-5G polymorphism and the risk for chronic kidney disease and diabetes. Reviewed

Hattori Y, Naito M, Satoh M, Nakatochi M, Naito H, Kato M, Takagi S, Matsunaga T, Seiki T, Sasakabe T, Suma S, Kawai S, Okada R, Hishida A, Hamajima N, Wakai K.

Toxicol Sci     2016.10

Importance of detoxifying enzymes in differentiating fibrotic development between SHRSP5/Dmcr and SHRSP rats. Reviewed

Naito H, Jia X, Yetti H, Yanagiba Y, Tamada H, Kitamori K, Hayashi Y, Wang D, Kato M, Ishii A, Nakajima T.

Environ Health Prev Med   Vol. 21 ( 5 ) page： 368-381   2016.9

Preliminary characterization of a murine model for 1-bromopropane neurotoxicity: Role of cytochrome P450. Reviewed

Zong C, Garner E, Huang C, Zhang X, Zhang L, Chang J, Toyokuni S, Hidenori I, Kato M, Sakurai T, Ichihara S, Ichihara G.

Toxicol Lett   Vol. 258   page： 249-58   2016.9

Epidemiological analysis of the association between hearing and barium in humans. Reviewed

Ohgami N, Mitsumatsu Y, Ahsan Nazmul, Akhand AA, Li X, Iida M, Yajima I, Naito M, Wakai K, Ohnuma S and Kato M.

J Expo Sci Environ Epidemiol   Vol. 26 ( 5 ) page： 488-93   2016.9

Nitric oxide synthase 2 is involved in the pro-tumorigenic potential of γδ17 T cells in melanoma. Reviewed

Douguet L, Bod L, Cherfils-Vicini J, Lengagne R, Labarthe L, Gilson E, Kato M, Avril M-F, Prévost-Blondel A.

OncoImmunology   Vol. 5 ( 8 ) page： e1208878   2016.8

Metallothionein MT2A A-5G polymorphism as a risk factor for chronic kidney disease and diabetes: Cross-sectional and cohort studies. Reviewed

Hattori Y, Naito M, Satoh M, Nakatochi M, Naito H, Kato M, Takagi S, Matsunaga T, Seiki T, Sasakabe T, Suma S, Kawai S, Okada R, Hishida A, Hamajima N, Wakai K.

Toxicol Sci   Vol. 152 ( 1 ) page： 181-93   2016.7

Noninvasive, label-free, three-dimensional imaging of melanoma with confocal photothermal microscopy: Differentiate malignant melanoma from benign tumor tissue. Reviewed

He J, Nan Wang N, Tsurui H, Kato M, Iida M, Kobayashi T.

Sci Rep   Vol. 6   page： 30209   2016.7

Reply to the commentary "To Gorelenkova Miller and Mieyal (2015): Sulfhydryl-mediated redox signaling in inflammation: role in neurodegenerative diseases" by Mieyal JJ. Reviewed

Kato M, Ninomiya H, Maeda M, Ilmiawati C, Al Hossain MMA, Yoshinaga M, Ohgami N.

Arch Toxicol   Vol. 90   page： 1523-4   2016.6

Different biological effects of a constant dose for single UVB irradiation with different intensities and exposure times. Reviewed

Iida M, Nakano C, Tamaki M, Hasegawa M, Tsuzuki T, Kato M.

Exp Dermatol   Vol. 25 ( 5 ) page： 386-8   2016.5

Commentary to Gorelenkova Miller and Mieyal (2015): Sulfhydryl-mediated redox signaling in inflammation: role in neurodegenerative diseases. Reviewed

Kato M, Ninomiya H, Maeda M, Tanaka N, Ilmiawati C, Yoshinaga M.

Arch Toxicol   Vol. 90 ( 4 ) page： 1017-8   2016.4

Transcription factor LSF (TFCP2) inhibits melanoma growth. Reviewed

Goto Y, Yajima I, Kumasaka M, Ohgami N, Tanaka A, Tsuzuki Toyonori, Inoue Y,Fukushima S, Ihn H, Kyoya M, Ohashi H, Kawakami T, Bennett DC and Kato M.

Oncotarget   Vol. 7 ( 2 ) page： 2379-90   2016.1

Efficacy of Dietary Lipid Control in Healing High-fat and High-cholesterol Diet-induced Fibrotic Steatohepatitis in Rats. Reviewed

Tamada H, Naito H, Kitamori K, Hayashi Y, Yamagishi N Kato M, Nakajima T.

PLoS ONE   Vol. 11 ( 1 ) page： e0145939   2016.1

Prevention of allergic rhinitis by ginger and the molecular basis of immunosuppression by 6-gingerol through T cell inactivation. Reviewed

Kawamoto Y, Ueno Y, Nakahashi E, Obayashi M, Sugihara K, Qiao S, Iida M, Yajima-Kumasaka M, Yajima I, Goto Y, Ohgami N, Kato M and Takeda K.

J Nutr Biochem   Vol. 27   page： 112-122   2016.1

Modulated expression levels of tyrosine kinases in spontaneously developed melanoma by single irradiation of non-thermal atmospheric pressure plasmas. Reviewed

Omata Y, Iida M, Yajima I, Ohgami N, Maeda M, Ninomiya H, Oshino R, Tsuzuki T, Hori M, Kato M.

Int J Clin Exp Pathol     page： in press   2016

Rapid dissemination of RET-transgene driven melanoma in the presence of Non-Obese Diabetic alleles: critical roles of Dectin-1 and Nitric-Oxide Synthase type 2. Reviewed

Dabbeche-Bouricha E, Araujo L, Kato M, Prevost-Blondel A, and Garchon H-J.

OncoImmunology   Vol. 5 ( 5 ) page： e1100793   2015.10

Macrophage depletion reduces postsurgical tumor recurrence and metastatic growth in a spontaneous murine model of melanoma. Reviewed

Tham M, Khoo K, Yeo KP, Kato M, Prevost-Blondel A, Angeli V, Abastado JP.

Oncotarget   Vol. 6 ( 26 ) page： 22857-68   2015.9

Carcinogenic risk of chromium, copper and arsenic in CCA-treated woods. Reviewed

Ohgami N, Yamanoshita O, Thang ND, Yajima I, Nakano C, Wu W, Ohnuma S, Kato M.

Environ Pollut   Vol. 206   page： 456-60   2015.8

Decreased expression levels of cell cycle regulators and matrix metalloproteinases in melanoma from RET-transgenic mice by single irradiation of non-equilibrium atmospheric pressure plasmas. Reviewed

Iida M, Omata Y, Nakano C, Yajima I, Tsuzuki T, Ishikawa K, Hori M, Kato M.

Int J Clin Exp Pathol   Vol. 8 ( 8 ) page： 9326-31   2015.8

Deltex-3-like (DTX3L) stimulates metastasis of melanoma through FAK/PI3K/AKT but not MEK/ERK pathway. Reviewed

Thang ND, Yajima I, Kumasaka M, Iida M, Suzuki T, Kato M.

Oncotarget   Vol. 6 ( 16 ) page： 14290-9   2015.6

Prenatal maternal blood triglyceride and fatty acid levels, not term birth dimensions, in relation to exposure to di(2-ethylhexyl)phthalate: a cross-sectional study. Reviewed

Jia X, Harada Y, Tagawa M, Naito H, Hayashi Y, Husna Y, Kato M, Sasaki S, Araki A, Miyashita C, Ikeno T, Kishi R, Nakajima T.

Enviorn Health Prev Med   Vol. 20 ( 3 ) page： 168-78   2015.5

Arsenic-mediated promotion of anchorage-independent growth through increased level of placental growth factor. Reviewed

Yajima I, Kumasaka MY, Ohnuma S, Ohgami N, Naito H, Shekhar HU, Omata Y, Kato M.

J Invest Dermatol   Vol. 135 ( 4 ) page： 1147-56   2015.4

Cupper oxide nanoparticles reduce vasculogenesis in transgenic zebrafish throufg down-regulation of VEGF expression and induction of apoptosis. Reviewed

Chang J, Ichihara G, Shimada Y, Tada-Oikawa S, Kuroyanagi J, Zhang B, Suzuki Y, Sehsah R, Kato M, Tanaka T, Ichihara S.

J Nanosci Nanotechnol   Vol. 15 ( 3 ) page： 2140-7   2015.3

Cigarette smoking causes hearing impairment among Bangladeshi population. Reviewed

Sumit AF, Das A, Sharmin Z, Ahsan N, Ohgami N, Kato M, Akhand AA.

PLoS ONE   Vol. 10 ( 3 ) page： e0118960   2015.3

Tumor stroma and chemokines control T cell migration into melanoma following Temozolomide treatment. Reviewed

Tan KW, Evrard M, Tham M, Hong M, Huang C, Kato M, Prevost-Blondel A, Donnadieu E, Ng LG, Abastado J-P.

OncoImmunology   Vol. 4 ( 2 ) page： e978709   2015.2

Correlated expression levels of Endothelin receptor B and Plexin C1 in melanoma. Reviewed

Kumasaka YM, Yajima I, Iida M, Takahashi H, Inoue Y, Fukushima S, Ihn H, Takeda K, Naito Y, Yoshikawa T, Kato M.

Am J Cancer Res   Vol. 5 ( 3 ) page： 1117-23   2015.2

Treatment of vemurafenib-resistant SKMEL-28 melanoma cells with paclitaxel. Reviewed

Thang ND, Kumasaka YM, Nghia PT, Yajima I, Kato M.

Asian Pac J Cancer Prev   Vol. 16 ( 2 ) page： 699-705   2015.2

Protective effects of Phyllanthus emblica leaf extract on sodium arsenite-mediated adverse effects in mice. Reviewed

Sayed S, Ahsan N, Kato M, Ohgami N, Rashid A, Akhand AA.

Nagoya J Med Sci   Vol. 77 ( 1-2 ) page： 145-53   2015.2

Lymphadenectomy promotes tumor growth and cancer cell dissemination in the spontaneous RET mouse model of human uveal melanoma. Reviewed

Pin YK, Khoo K, Tham M, Karwai T, Hwee TC, Puaux A-L, Phua MLC, KatoM, Veronique A, Abastado JP.

Oncotarget     page： in press   2015

Plasma with high electron density and Plasma-Activated Medium for Cancer Treatment. Reviewed

Tanaka H, Mizuno M, Ishikawa K, Kondo H, Takeda K, Hashizume H, Nakamura K, Utsumi F, Kajiyama H, Kano H, Okazaki Y, Toyokuni S, Akiyama S, Maruyama S, Yamada S, Kodera Y, Kaneko H, Terasaki H, Hara H, Adachi T, Iida M, Yajima I, Kato M, Kikkawa F, Hori M.

Clinical Plasma Medicine     page： in press   2015

Melanoma-Initiating Cells Exploit M2 Macrophage TGF. Reviewed

Tham M, Tan KW, Keeble J, Wang X, Hubert S, Barron L, Tan NS, Kato M, Prevost-Blondel A, Angeli V, Abastado J-P.

Oncotarget   Vol. 5 ( 23 ) page： 12027-42   2014.12

Synergistic effect of exposure to zinc oxide nanoparticle on inflammatory response to bleomycin-induced pulmonary fibrosis in mice. Reviewed

Wu W, Ichihara G, Hashimoto N, Hasegawa Y, Hayashi Y, Tada-Oikawa S, Suzuki Y, Chang J, Kato M, D'Alessandro-Gabazza CN, Gabazza EC, Ichihara S.

Int J Mol Sci   Vol. 16 ( 1 ) page： 660-76   2014.12

Commentary to Pastore et al (2014): Epidermal growth factor receptor signalling in keratinocyte biology: implications for skin toxicity of tyrosine kinase inhibitors. Reviewed

Takeda K, Kawamoto Y, Iida M, Omata Y, Zou C, Kato M.

Arch Toxicol     2014.9

Non-thermal atmospheric pressure plasmas as a novel candidate for preventive therapy of melanoma. Reviewed

Omata Y, Iida M, Yajima I, Takeda K, Ohgami N, Masaru Hori H, Kato M.

Enviorn Health Prev Med   Vol. 19   page： 367-9   2014.9

The transcription factor IRF1 dictates the IL-21-dependent anticancer functions of TH9 cells.

Vegran F, Berger H, Boidot R, Mignot G, Bruchard M, Dosset M, Chalmin F, Rebe C, Derangere V, Ryffel B, Kato M, Prevost-Blondel A, Ghiringhelli F and Apetoh L

Nature Immunology   Vol. 15   page： 758-66   2014.8

A possible role of chenodeoxycholic acid and glycine-conjugated bile acids in fibrotic steatohepatitis in a dietary rat model. Reviewed

Jia X, Suzuki Y, Naito H, Yetti H, Kitamori K, Hayashi Y, Kaneko R, Nomura M, Yamori Y, Zaitsu K, Kato M, Ishii A, Nakajima T.

Dig Dis Sci   Vol. 59 ( 7 ) page： 1490-501   2014.7

Effects of non-thermal atmospheric pressure plasma irradiation on expression levels of matrix metalloproteinases in benign melanocytic tumors in RET-transgenic mice. Reviewed

Iida M,Yajima I, Ohgami N, Tamura H, Takeda K, Ichihara S, Hori M, Kato M.

Eur J Dermatol   Vol. 24 ( 3 ) page： 392-4   2014.6

Non-equilibrium atmospheric pressure plasmas modulate cell cycle-related gene expression levels in melanocytic tumors of RET-transgenic mice. Reviewed

Yajima I, Iida M, Kumasaka MY, Ohgami N, Chang J, Ichihara S, Hori M, Kato M.

Exp Dermatol   Vol. 23 ( 6 ) page： 424-5   2014.6

Bidirectional functions of arsenic as a carcinogen and an anticancer agent in human squamous cell carcinoma. Reviewed

Thang ND, Yajima I, Kumasaka M, Kato M.

PLoS ONE   Vol. 9 ( 5 ) page： e96945   2014.5

Commentary to Krishna et al. (2014): Brain deposition and neurotoxicity of manganese in adult mice exposed via the drinking water.

Kumasaka MY, Yajima I, Ohgami N, Naito H, Omata Y, Kato M.

Arch Toxicol   Vol. 88 ( 5 ) page： 1185-6   2014.5

Actin-binding Protein, Espin: a Novel Metastatic Regulator for Melanoma. Reviewed

Yanagishita T, Yajima I, Kumasaka M, Kawamoto Y, Tsuzuki T, Matsumoto Y, Watanabe D, Kato M.

Mol Cancer Res   Vol. 12 ( 3 ) page： 440-6   2014.3

GNG2 inhibits invasion of human malignant melanoma cells with decreased FAK activity. Reviewed

Yajima I, Kumasaka MY, Yamanoshita O, Zou C, Li X, Ohgami N, Kato M.

Am J Cancer Res   Vol. 4 ( 2 ) page： 182-8   2014.3

Expression of proteins associated with adipocyte lipolysis was significantly changed in the adipose tissues of the obese spontaneously hypertensive/NDmcr-cp rat. Reviewed

Chang J, Oikawa S, Iwahashi H, Kitagawa E, Takeuchi I, Yuda M, Kato C, Yamada Y, Ichihara G, Kato M, Ichihara S.

Diabetol Metab Syndr   Vol. 6 ( 1 ) page： 8   2014.1

Inflammatory monocytes are potent anti-tumor effectors controlled by regulatory CD4+ T cells. Reviewed

Pommier A, Delpoux A, Audemard A, Martin B, Douguet L, Lengagne R, Campion AL, Kato M, Avril MF, Auffray C, Lucas B, Prévost-Blondel A.

Proc Natl Acad Sci USA   Vol. 110 ( 32 ) page： 13085-90   2013.8

Enhanced constitutive invasion activity in human nontumorigenic keratinocytes exposed to a low level of barium for a long time.

Thang ND, Yajima I, Ohnuma S, Ohgami N, Kumasaka MY, Ichihara G, Kato M.

Envion Toxicol     2013.6

Comparison of barium and arsenic concentrations in well drinking water and in human body samples and a novel remediation system for these elements in well drinking water

Kato M, Kumasaka YM, Ohnuma S, Furuta A, Kato Y, Shekhar HU, Kojima M, Koike Y, Thang ND, Ohgami N, Ly TB, Jia X, Yetti H, Naito H, Ichihara G, Yajima I

PLoS ONE   Vol. 8 ( 6 )   2013.6

Cyclophosphamide promotes chronic inflammation-dependent immunosuppression and prevents anti-tumor response in melanoma

Sevko A, Sade-Feldman M, Kanterman J, Michels T, Falk C, Ramacher M, Kato M,

J Invest Dermatol   Vol. 133 ( 6 ) page： 1610-1619   2013.6

Difference in urinary arsenic metabolites of diabetic and non-diabetic subjects in Bangladesh

Nizam S, Kato M, Yatsuya H Khalequzzaman Md, Ohnuma S, Naito H, Nakajima T

Int J Environ Res Public Health   Vol. 10 ( 3 ) page： 1006-19   2013.3

Anti-tumor Effect of Paclitaxel is Mediated by Inhibition of MDSCs and Chronic Inflammation in the Spontaneous Melanoma Model

Sevko A, Michels T, Vrohlings M, Umansky L, Beckhove P, Kato M, Shurin GV, Shurin MR, Umansky V

J Immunol   Vol. 190 ( 5 ) page： 2464-71   2013.3

Enhanced carcinogenicity by coexposure to arsenic and iron and a novel remediation system for the elements in well drinking water.

Kumasaka YM, Yamanoshita O, Shimizu S, Ohnuma S, Furuta A, Yajima I, Nizam S, Khalequzzaman M, Shekhar UH, Nakajima T, Kato M.

Arch Toxicol   Vol. 87 ( 3 ) page： 439-47   2013.3

Hearing impairments caused by genetic and environmental factors.

Ohgami N, Iida M, Yajima I, Tamura H, Ohgami K, Kato M.

Environ Health Prev Med   Vol. 18 ( 1 ) page： 10-5   2013.1

Tumor-Expressed Inducible Nitric Oxide Synthase Controls Induction of Functional Myeloid-Derived Suppressor Cells through Modulation of Vascular Endothelial Growth Factor Release.

Jayaraman P, Parikh F, Lopez-Rivera E, Hailemichael Y, Clark A, Ma G, Cannan D, Ramacher M, Kato M, Overwijk WW, Chen SH, Umansky VY, Sikora AG

J Immunol   Vol. 188 ( 11 ) page： 5365-76   2012.6

Cancer-Induced Immunosuppression: IL-18-Elicited Immunoablative NK Cells.

Terme M, Ullrich E, Aymeric L, Meinhardt K, Coudert JD, Desbois M, Ghiringhelli F, Viaud S, Ryffel B, Yagita H, Chen L, Mécheri S, Kaplanski G, Prévost-Blondel A, Kato M, Schultze JL, Tartour E, Kroemer G, Degli-Esposti M, Chaput N, Zitvogel L

Cancer Res   Vol. 72 ( 1 ) page： 2757-67   2012.6

Barium inhibits arsenic-mediated apoptotic cell death in human squamous cell carcinoma cells.

Yajima I, Uemura N, Nizam S, Khalequzzaman M, Thnag ND, Kumasaka YM, Akhand AA, Shekhar HU, Nakajima T, Kato M

Arch Toxicol   Vol. 86 ( 6 ) page： 961-73   2012.6

A novel hairless mouse model for malignant melanoma.

Thang ND, Yajima I, Nakagawa K, Tsuzuki T, Kumasaka YM, Ohgami N, Thuy LB, Iwamoto T, Watanabe D, Kato M

J Dermatol Sci   Vol. 65 ( 3 ) page： 207-12   2012.3

Partial impairment of c-Ret at tyrosine 1062 accelerates age-related hearing loss in mice.

Ohgami N, Ida-Etoh M, Sakashita N, Sone M, Nakashima N, Tabuchi K, Hoshino T, Shimada A, Tsuzuki T, Yamamoto M, Sobue G, Jijiwa M, Asai N, Hara A, Takahashi M, Kato M

Neurobiol Aging   Vol. 33 ( 3 ) page： 626.e25-34   2012.3

Functional analysis of GNG2 in human malignant melanoma cells.

Yajima I, Kumasaka YM, Tamura H, Ohgami N, Kato M

J Dermatol Sci   Vol. 68 ( 3 ) page： 172-8   2012.1

RAS/RAF/MEK/ERK and PI3K/PTEN/AKT signaling in malignant melanoma progression and therapy

Yajima I, Kumasaka YM, Thang ND, Goto Y, Takeda K, Yamanoshita O, Iida M, Ohgami N, Tamura H, Kawamoto Y, Kato M

Dermatol Res Prac   Vol. 2012   page： 354191   2012

c-Ret-mediated hearing losses

Ohgami N, Tamura H, Ohgami K, Iida M, Yajima I, Kumasaka YM, Goto Y, Sone M, Nakashima T, Kato M

Int J Clin Exp Pathol   Vol. 5 ( 1 ) page： 23-8   2012

Reduced GNG2 expression levels in mouse malignant melanomas and human melanoma cell lines.

Yajima I, Kumasaka YM, Naito Y, Yoshikawa T, Takahashi H, Funasaka Y, Suzuki T, Kato M

Am J Cancer Res   Vol. 2 ( 3 ) page： 322-329   2012

Chronic exposure to low frequency noise at moderate levels causes impaired balance in mice

Tamura H, Ohgami N, Yajima I, Iida M, Ohgami K, Fujii N, Itabe H, Kusudo T, Yamashita H, Kato M

PLoS ONE   Vol. 7 ( 6 ) page： e39807   2012

c-Ret-mediated hearing losses

Ohgami N, Ida M, Shimotake T, Sakashita N, Sone M, Nakashima T, Tabuchi K, Hoshino T, Shimada A, Tsuzuki T, Yamamoto M, Sobue G, Jijiwa M, Asai N, Hara A, Takahashi M, Kato M

Proc Natl Acad Sci USA   Vol. 107 ( 29 ) page： 13051-6   2012

Chemotherapy induces intratumoral expression of chemokines in cutaneous melanoma, favoring T cell infiltration and tumor control.

Hong M, Puaux AL, Huang C, Loumagne L, Tow C, Mackay C, Kato M, Prevost-Blondel A, Avril MF, Nardin A, Abastado JP

Cancer Res   Vol. 71 ( 22 ) page： 6997-7009   2011.11

Chronic inflammation promotes myeloid-derived suppressor cell activation blocking antitumor immunity in transgenic mouse melanoma model.

Meyer C, Sevko A, Ramacher M, Bazhin AV, Falk C, Osen W, Borrello I, Kato M, Schadendorf D, Baniyash M, Umansky V

Proc Natl Acad Sci USA   Vol. 108 ( 41 ) page： 17111-6   2011.10

Mesenchymal transition and dissemination of cancer cells is driven by myeloid-derived suppressor cells infiltrating the primary tumor.

Toh B, Wang X, Keeble J, Sim WJ, Khoo K, Wong WC, Kato M, Prevost-Blondel A, Thiery JP, Abastado JP

PLoS Biol   Vol. 9 ( 9 ) page： e1001162   2011.9

Proteomic identification of hippocampal proteins vulnerable to oxidative stress in excitotoxin-induced acute neuronal injury.

Furukawa A, Kawamoto Y, Chiba Y, Takei S, Hasegawa-Ishii S, Kawamura N, Yoshikawa K, Hosokawa M, Oikawa S, Kato M, Shimada A

Neurobiol Dis   Vol. 43 ( 3 ) page： 706-14   2011.9

Requirement of endothelin receptor B expressed in spiral ganglion neurons for postnatal development of hearing.

Ida-Eto M, Ohgami N, Iida M, Yajima I, Kumasaka MY, Takaiwa K, Kimitsuki T, Sone M, Nakashima T, Tsuzuki T, Komune S, Yanagisawa M, Kato M

J Biol Chem   Vol. 286 ( 34 ) page： 29621-6   2011.8

IL-18 induces PD-1-dependent immunosuppression in cancer.

Terme M, Ullrich E, Aymeric L, Meinhardt K, Desbois M, Delahaye N, Viaud S, Ryffel B, Yagita H, Kaplanski G, Prévost-Blondel A, Kato M, Schultze JL, Tartour E, Kroemer G, Chaput N, Zitvogel L

Cancer Res   Vol. 71 ( 16 ) page： 5393-9   2011.8

Sunlight exposure-mediated DNA damage in young adults.

Kato M, Iida M, Goto Y, Kondo T, Yajima I

Cancer Epidemiol Biomaker Prevent   Vol. 20 ( 8 ) page： 1622-8   2011.8

BMP-4 down-regulates the expression of Ret in murine melanocyte precursors.

Kawakami T, Kumasaka M, Kato M, Mizoguchi M, Soma Y

J Dermatol Sci   Vol. 63 ( 1 ) page： 66-9   2011.7

L-cysteine as a regulator for arsenic-mediated cancer-promoting and anti-cancer effects.

Kato M, Kumasaka MY, Takeda K, Hossain K, Iida M, Yajima I, Goto Y, Ohgami N

Toxcol In Vitro   Vol. 25   page： 623–629   2011.4

Effects of light smoking on extra-high-frequency auditory thresholds in young adults

Ohgami N, Kondo T, Kato M

Toxicol Ind Health   Vol. 27   page： 143-147   2011.3

T Cells Contribute to Tumor Progression by Favoring Pro-Tumoral Properties of Intra-Tumoral Myeloid Cells in a Mouse Model for Spontaneous Melanoma

Lengagne R, Pommier A, Caron J, Douguet L, Garcette M, Kato M, Avril M-F, Abastado J-P, Bercovici N, Lucas B and Prevost-Blondel A

PLoS ONE   Vol. 6 ( 5 ) page： e20235   2011

Molecular network associated with MITF on skin melanoma development and progression.

Yajima I, Kumasaka YM, Thang ND, Goto Y, Takeda K, Iida M, Ohgami N, Tamura H, Yamanoshita O, Kawamoto Y, Furukawa K, Kato M

J Skin Cancer   Vol. 2011   page： 730170   2011

Control of Genetically Designed Protein Tyrosine Kinase Activities by Environment-Linked Redox Reactions

Nakashima I, Kawamoto Y, Takeda K, Kato M

Enzyme Res   Vol. 10   page： 896567   2011

Antioxidative effects of cherry leaves extract on tert-butyl hydroperoxide-mediated cytotoxicity through regulation of thioredoxin-2 protein expression level.

Taguchi N, Uemura N, Goto Y, Sakura M, Hara K, Niwa M, Iida M, Yanagishita T, Watanabe D, Kato M

J Toxicol Environ Health A   Vol. 74 ( 18 ) page： 1240-7   2011

c-Ret-mediated hearing loss in mice with Hirschsprung disease.

Ohgami N, Ida M, Shimotake T, Sakashita N, Sone M, Nakashima T, Tabuchi K,

Proc Natl Acad Sci USA   Vol. 107 ( 29 ) page： 13051-6   2010.7

Targeting Surface Nucleolin with a Multivalent Pseudopeptide Delays Development of Spontaneous Melanoma in RET Transgenic Mice.

Khoury DE, Destouches D, Lengagne R, Krust B, Hamma-Kourbali Y, Garcette M, Niro S, Kato M, Briand J-P, Courty J, Hovanessian AG, Prévost-Blondel A

BMC Cancer   Vol. 10   page： 325   2010.6

c-Ret-mediated hearing loss in mice with Hirschsprung disease. Reviewed

Ohgami N, Ida M, Shimotake T, Sakashita N, Sone M, Nakashima T, Tabuchi K, Hoshino T, Shimada A, Tsuzuki T, Yamamoto M, Sobue G, Jijiwa M, Asai N, Hara A, Takahashi M, Kato M.

Proc Natl Acad Sci USA   Vol. 107 ( 29 ) page： 13051-6   2010.6

Tumor cells disseminate early but immunosurveillance limits metastatic outgrowth in a mouse model of melanoma.

Eyles J, Puaux A, Wang J, Toh B, Prakash C, Hong M, Zheng L, Ong LC, Jin Y, Kato M, Blondel AP, Chow P, Yang H, Abastado J-P

J Clin Invest   Vol. 120 ( 6 ) page： 2030-9   2010.6

A redox-linked novel pathway for arsenic-mediated RET tyrosine kinase activation

Kato M, Takeda K, Hossain K, Thang D. Nguyen, Kaneko Y, Kumasaka M, Yamanoshita O, Uemura N, Takahashi M, Ohgami N, Kawamoto Y

J Cell Biochem   Vol. 110   page： 399-407   2010.5

c-RET molecule in malignant melanoma from oncogenic RET-carrying transgenic mice and human cell lines

Ohshima Y, Yajima I, Takeda K, Iida M, Kumasaka M, Matsumoto Y, Kato M

PLoS ONE   Vol. 5 ( 4 ) page： e10279   2010.4

Ergün S and Schadendorf D: Resistance to anti-angiogenic therapy is directed by vascular phenotype, vessel stabilization and maturation in malignant melanoma.

Helfrich I, Scheffrahn I, Bartling S, Weis J, von Felbert V, Middleton M, Kato M

J Exp Med   Vol. 207 ( 3 ) page： 491-503   2010.3

Increased CD109 expression levels in human malignant melanoma

Ohshima Y, Yajima I, Kumasaka YM, Yanagishita T, Watanabe D, Takahashi M, Inoue Y, Ihn H, Matsumoto Y, Kato M

J Dermatol Sci   Vol. 57 ( 2 ) page： 140-2   2010.2

A Novel Mouse Model for de novo melanoma

Kumasaka YM, Yajima I, Hossain K, Iida M, Tsuzuki T, Ohno T, Takahashi M, Yanagisawa M, Kato M

Cancer Res   Vol. 70 ( 1 ) page： 24-9   2010.1

Toxic Elements in Well Water from Malaysia

Kato M, Ohnuma S, Kato Y, Thang D. Nguyen, Yajima I, Hoque Z. Mohammad, Shekhar U. Hossain

Toxicol Environ Chem   Vol. 92 ( 9 ) page： 1609-12   2010

1,4-butanediyl-bismethanethiosulfonate (BMTS) induces reactive oxygen species-mediated apoptotic signals independent of stress-activated MAPK cascade in Jurkat cells.

Hossain K, Kawamoto Y, Hamada M, Akhand A, Yanagishita T, Hoque Md. A, Tsuboi H, Kato M, Nakashima I

J Cell Biochem   Vol. 108 ( 5 ) page： 1059-65   2009.12

Skin Melanoma Development in Ret Transgenic Mice Despite the Depletion of CD25+FoxP3+ Regulatory T-Cells in Lymphoid Organs.

Kimpfler S, Ring S, Falk C, Osen W, Kato M, Mahnke K, Schadendorf D, Umansky V

J Immunol   Vol. 183 ( 10 ) page： 6330-7   2009.11

Mendelsohn C, Costantini F: Ret-dependent cell rearrangements in the Wolffian duct epithelium initiate ureteric bud morphogenesis.

Chi X, Michos O, Shakya R, Riccio P, Enomoto H, Licht JD, Asai N, Takahashi M, Ohgami N, Kato M

Dev Cell   Vol. 17 ( 2 ) page： 199-209   2009.8

Activation of p38 MAPK Drives Dendritic Cells to Become Tolerogenic in Ret Transgenic Mice Spontaneously Developing Melanoma.

Zhao F, Falk C, Osen W, Kato M, Schadendorf D, Umansky V

Clin Cancer Res   Vol. 15 ( 13 ) page： 4382-90   2009.7

Zinc finger protein 28 as a novel melanoma-related molecule.

Yajima I, Kumasaka M, Thang ND, Yanagishita T, Ohgami N, Kallenberg D, Naito Y, Yoshikawa T, Sakashita N, Kato M.

J Dermatol Sci   Vol. 55 ( 1 ) page： 68-70   2009.7

NCRs and DNAM-1 mediate NK cell recognition and lysis of human and mouse melanoma cell lines in vitro and in vivo.

Lakshmikanth T, Burke S, Ali TH, Kimpfler S, Ursini F, a Ruggeri L, Capanni M, Umansky V, Paschen A, Sucker A, Pende D, Groh V, Biassoni R, Höglund P, Kato M, Shibuya K, Schadendorf D, Anichini A, Ferrone S, Velardi A, Kärre K, Shibuya A, Carbone E, Colucci F.

J Clin Invest   Vol. 119 ( 5 ) page： 1251-63   2009.5

Melanoma Specific Memory T Cells Are Functionally Active in Ret Transgenic Mice Without Macroscopical Tumors.

Umansky V, Abschuetz O, Osen W, Ramacher M, Zhao F, Kato M

Cancer Res   Vol. 68 ( 22 ) page： 9451-8   2008.11

BMP-4 Upregulates Kit Expression in Mouse Melanoblasts prior to the Kit-Dependent Cycle of Melanogenesis.

Kawakami T, Kimura S, Kawa Y, Kato M, Mizoguchi M, Soma Y

J Invest Dermatol   Vol. 128 ( 5 ) page： 1220-6   2008.5

Distinct role for CD8 T cells toward cutaneous tumors and visceral metastases.

Lengagne R, Graff-Dubois S, Garcette M, Renia L, Kato M, Guillet J, Engelhard HV, Avril M, Abastado J and Prévost-Blondel A

J Immunol   Vol. 180 ( 1 ) page： 130-7   2008.1

Arsenic enhances matrix metalloproteinase-14 expression in fibroblasts.

Kato M, Hossain K, Iida M, Sato H, Uemura N, Goto Y

J Toxicol Environ Health A   Vol. 71 ( 16 ) page： 1053-5   2008

Protective Effect of Hyperpigmented Skin on Ultraviolet-Mediated Cutaneous Cancer Development.

Kato M, Ohgami N, Kawamoto Y, Tsuzuki T, Hossain K, Yanagishita T, Ohshima Y, Tsuboi H, Yamanoshita O, Matsumoto Y, Takahashi M, Nakashima I

J Invest Dermatol   Vol. 127 ( 5 ) page： 1244-9   2007.5

Novel hairless RET-transgenic mouse line with melanocytic nevi and anagen hair follicles.

Kato M, Takeda K, Kawamoto Y, Tsuzuki T, Kato Y, Ohno T, Hossain K, Iftakhar-E-Khuda I, Ohgami N, Isobe K, Takahashi M, Nakashima I

J Invest Dermatol   Vol. 126 ( 11 ) page： 2547-50   2006.11

A PKC-mediated backup mechanism of the MXXCW motif-linked switch for initiating tyrosine kinase activities.

Takeda K, Kawamoto Y, Okuno Y, Kato M, Takahashi M, Suzuki H, Isobe K, Nakashima I

FEBS Letters   Vol. 580   page： 839-43   2006.2

5-aminolaevulinic acid photodynamic therapy in a transgenic mouse model of skin melanoma.

Córdoba F, Braathen LR, Weissenberger J, Vallan C, Kato M, Nakashima I, Weis J,

Exp Dermatology   Vol. 14   page： 429-37   2005.6

Interleukin-6 gene ablation in a transgenic mouse model of malignant skin melanoma.

von Felbert V, Cordoba F, Weissenberger J, Vallan C, Kato M, Nakashima I,

Am J Pathol   Vol. 166   page： 831-41   2005.3

Redox control of catalytic activities of membrane-associated protein tyrosine kinases.

Nakashima I, Takeda K, Kawamoto Y, Okuno Y, Kato M, Suzuki H

Arch Biochem Biophys   Vol. 434   page： 3-10   2005.2

A novel RFP-RET transgenic mouse model with abundant eumelanin in the cochlea.

Hayashi H, Sone M, Ito S, Wakamatsu K, Kato M, Nakashima I and Nakashima T

Hear Res   Vol. 195   page： 35-40   2004.9

Identification of RET Autophosphorylation Sites by Mass Spectrometry.

J Biol Chem

J Biol Chem   Vol. 279   page： 14213-14224   2004.4

Spontaneous vitiligo in an animal model for human melanoma: Role of tumorspecific CD8+ T cells.

Lengagne R, Le Gal F-A, Garcette M, Fiette L, Ave P, Kato M, Briand J-P, Massot C, Nakashima I, Rénia L, Guillet J-G, Prévost-Blondel A

Cancer Res   Vol. 64   page： 1496-501   2004.2

c-Kit-targeting immunotherapy for hereditary melanoma in a mouse model.

Kato M, Takeda K, Kawamoto Y, Tsuzuki T, Hossain K, Tamakoshi A, Kunisada T, Kambayashi Y, Ogino K, Takahashi M, Nakashima I

Cancer Res   Vol. 64   page： 801-806   2004.2

Formation of Superoxide Anion during Ferrous Ion-Induced Decomposition of Linoleic Acid Hydroperoxide under Aerobic Conditions.

Kambayashi Y, Tero-Kubota S, Yamamoto Y, Kato M, Nakano M, Yagi K, Ogino K.

J Biochem   Vol. 34   page： 903-909   2003.12

IgA1 molecules produced by tonsillar lymphocytes are under-O-glycosylated in IgA nephropathy.

Horie A, Hiki Y, Odani H, Yasuda Y, Takahashi M, Kato M, Iwase H, Kobayashi Y, Nakashima I, Maeda K

Am J Kidney Dis   Vol. 42   page： 486-96   2003.9

4-Hydoroxynonenal triggers multistep signal transduction cascades for supression of cellular functions.

Nakashima I, Liu W, Akhand AA, Takeda K, Kawamoto K, Kato M, Suzuki H

Mol Aspects Med   Vol. 24   page： 231-238   2003.8

Protein phosphatase 2A-linked and -unlinked caspase-dependent pathways for downregulation of Akt kinase triggered by 4-hydroxynonenal.

Liu W, Akhand AA, Takeda K, Kawamoto Y, Itoigawa M, Kato M, Suzuki H,

Cell Death Differ   Vol. 10   page： 772-81   2003.7

Vam10p Defines a Sec18p-independent Step of Priming which allows Yeast Vacuole Tethering.

Kato M and Wickner W

Proc Natl Acad Sci USA   Vol. 100   page： 6398-6403   2003.5

Caspase activation is accelerated by the inhibition of arsenite-induced, membrane rafts-dependent Akt activation.

Hossain K, Akhand AA, Kawamoto Y, Du J, Takeda K, Wu J, Yoshihara M, Tsuboi H, Kato M, Suzuki H, Nakashima I

Free Radic Biol Med   Vol. 34   page： 598-606   2003.3

Redox control of T cell death.

Nakashima I, Suzuki H, Akhand AA, Kato M

Antioxid Redox Signal   Vol. 4 ( 3 ) page： 353-356   2002.6

Redox-Linked Signal Tansduction Pathways for Protein Tyrosine Kinase Activation.

Nakashima I, Kato M, Akhand AA, Suzuki H, Takeda K, Hossain K, Kawamoto Y

Antioxid Redox Signal   Vol. 4 ( 3 ) page： 517-531   2002.6

Redox-linked cell surface-oriented signaling for T-cell death.

Akhand AA, Du J, Liu W, Hossain K, Miyata T, Nagase F, Kato M, Suzuki H, Nakashima I

Antioxid Redox Signal   Vol. 4 ( 3 ) page： 445-454   2002.6

Repair by Src Kinase of Function-impaired RET with Multiple Endocrine Neoplasia Type 2A Mutation with Substitutions of Tyrosines in the COOH-Terminal Kinase Domain for Phenylalanine.

Kato M, Takeda K, Kawamoto Y, Iwashita T, Akhand AA, Senga T, Yamamoto M, Sobue G, Hamaguchi M, Takahashi M and Nakashima I

Cancer Res   Vol. 62 ( 8 ) page： 2414-22   2002.4

Evidence of Both Extra- and Intracellular Cysteine Targets of Protein Modification for Activation of RET Kinase.

Akhand AA, Ikeyama T, Akazawa S, Kato M, Hossain K, Takeda K, Suzuki H, Takahashi M, Nakashima I

Biochem Biophys Res Commun   Vol. 292 ( 4 ) page： 826-31   2002.4

Genomics Analysis of Homotypic Vacuole Fusion.

Seely S, Kato M, Margolis N, Wickner W, Eitzen G.

Mol Biol Cell   Vol. 13 ( 3 ) page： 782-794   2002.3

Glyoxal and methylglyoxal induce lyoxal and methyglyoxal induce aggergation and inactivation of ERK in human endothelial cells.

Akhand AA, Hossain K, Kato M, Miyata T, Du J, Suzuki H, Kurokawa K, Nakashima I

Free Radic Biol Med   Vol. 31 ( 10 ) page： 1228-1235   2001.11

RET tyrosine kinase enhances hair growth in association with promotion of melanogenesis.

Kato M, Takeda K, Kawamoto Y, Tuzuki T, Dai Y, Nakayama S, Toriyama K, Tamada Y, Takahashi M, Nakashima I

Oncogene   Vol. 20 ( 51 ) page： 7536-7541   2001.11

T-cell Immunity-based Inhibitory Effects of Orally Administered Herbal Medicine Juzen-taiho-to on the Growth of Primarily Developed Melanocytic Tumors in RET-Transgenic Mice.

Dai Y, Kato M, Takeda K, Kawamoto Y, Akhand AA, Hossain K, Suzuki H, and Nakashima I.

J Invest Dermatol   Vol. 117 ( 3 ) page： 694-701   2001.9

Preserved phosphorylation of RET receptor protein in spinal motor neurons of patients with amyotrophic lateral sclerosis: an immunohistochemical study by a phosphorylation-specific antibody at tyrosine 1062.

Yamamoto M, Li M, Mitsuma N, Ito S, Kato M, Takahashi M and Sobue G

Brain Res   Vol. 912 ( 1 ) page： 89-94   2001.8

Ergosterol is required for the Sec18/ATP-dpendent priming step of homotypic vacuole fusion.

Kato M and Wickner W

EMBO J   Vol. 20 ( 15 ) page： 4035-4040   2001.8

Distinct Involvement of NF-kappaB and p38 Mitogen-activated Protein Kinase Pathways in Serum Deprivation-mediated Stimulation of Inducible Nitric Oxide Synthase and Its Inhibition by 4-hydroxynonenal.

Liu W, Kato M, Itoigawa M, Murakami H, Yajima M, Wu J, Ishikawa N, Nakashima I

J Cell Bichem   Vol. 83 ( 2 ) page： 271-280   2001.8

Glyoxal and methylglyoxal trigger distinct signals for MAP family kinases and caspase activation in human endothelial cells.

Akhand AA, Hossain K, Mitsui H, Kato M, Miyata T, Inagi R, Du J, Takeda K, Kawamoto Y, Suzuki H, Kurokawa K and Nakashima I

Free Rad Biol Med   Vol. 31 ( 1 ) page： 20-30   2001.7

Osmotic stress-mediated activation of RET kinases involves intracellular disulfide-bonded dimer formation.

Takeda K, Kato M, Wu J, Iwashita T, Suzuki H, Takahashi M and Nakashima I

Antioxid Redox Signal   Vol. 3 ( 3 ) page： 473-482   2001.6

Cepharanthine Activates Caspases and Induces Apoptosis in Jurkat and K562 Human Leukemia Cell Lines.

Wu J, Suzuki H, Zhou YW, Liu W, Yoshihara M, Kato M, Akhand AA, Hayakawa A, Takeuchi K, Hossain K, Kurosawa M and Nakashima I

J Cell Biochem   Vol. 82 ( 2 ) page： 200-214   2001

Acrolein induces activation of the epidermal growth factor receptor of human keratinocytes for cell death.

Takeuchi K, Kato M, Suzuki H, Akhand AA, Wu J, Hossain K, Miyata T, Matsumoto Y, Nimura Y, Nakashima I.

J Cell Biochem   Vol. 81 ( 4 ) page： 679-88   2001

Ultraviolet Radiation Induces Both Full Activation of Ret Kinase and Malignant Melanocytic Tumor Promotion in RFP-RET-Transgenic Mice.

Kato M, Liu W, Akhand AA, Hossain K, Takeda K, Takahashi M and Nakashima I

J Invest Dermatol   Vol. 115 ( 6 ) page： 1157-1158   2000.12

Mapping of melanoma modifier loci in Ret transgenic mice.

Dragani TA, Peissel B, Zanesi N, Aloisi A, Dai Y, Kato M, Suzuki H, Nakashima I

Jpn J Cancer Res   Vol. 91 ( 11 ) page： 1142-7   2000.11

Arsenite induces apoptosis of murine T lymphocytes through membrane rafts- linked signaling for activation of c-Jun amino terminal kinase1.

Hossain K, Akhand AA, Kato M, Du J, Takeda K, Wu J, Takeuchi K, Liu W, Suzuki H and Nakashima I

J Immunol   Vol. 165 ( 8 ) page： 4290-4297   2000.10

Amount of pollen has an influence on the levels of soluble tumor necrosis factor receptors in patients with pollinosis.

Kato M, Kato Y, Takeuchi K and Nakashima I

Arch Otolaryngol Head Neck Surg   Vol. 126 ( 8 ) page： 997-1000   2000.8

Further characterization of the Sho-saiko-to-mediated anti-tumor effect on melanoma developed in RET- transgenic mice.

Kato M, Isobe K, Dai Y, Liu W, Takahashi M and Nakashima I

Invest Dermatol   Vol. 114 ( 3 ) page： 599-601   2000.3

4-Hydroxynonenal induces a cellular redox status-related activation of the caspase cascade for apoptotic cell death.

Liu W, Kato M, Akhand AA, Hayakawa A, Suzuki H, Miyata T, Hotta Y, Ishikawa N and Nakashima I

J Cell Sci   Vol. 113 ( 4 ) page： 635-641   2000.2

Ultraviolet light induces redox reaction-mediated dimerization and superactivation of oncogenic Ret tyrosine kinases.

Kato M, Iwashita T, Takeda K, Akhand AA, Liu W, Yoshihara M, Asai N, Suzuki H, Takahashi M and Nakashima I

Mol Biol Cell   Vol. 11 ( 1 ) page： 93-101   2000.1

Chemical reaction-mediated alternative signalling pathway in cells of the immune system.

Nakashima I, Kato M, Akhand AA, Du J, Liu W, Dai Y, Suzuki H, Senga T,

Current Trends in Immunology   Vol. 3   page： 45-58   2000

Molecular mechanism of activation and superactivation of Ret tyrosine kinases by ultraviolet light irradiation.

Kato M, Iwashita T, Akhand AA, Liu W, Takeda K, Takeuchi K, Yoshihara M,

Antioxid Redox Signal   Vol. 2 ( 4 ) page： 841-849   2000

Normal regulatory alpha/beta T cells effectively eliminate abnormally activated T cells lacking the interleukin 2 receptor beta in vivo.

Suzuki H, Zhou YW, Kato M, Mak TW and Nakashima I

J Exp Med   Vol. 190 ( 11 ) page： 1561-72   1999.12

Different serum soluble Fas levels in patients with allergic rhinitis and bronchial asthma.

Kato M, Nozaki Y, Yoshimoto T, Tamada Y, Kageyama M, Yamashita T, Kurimoto F and Nakashima I

Allergy   Vol. 54 ( 12 ) page： 1299-1302   1999.12

Nitric oxide controls src kinase activity through a sulfhydryl group modification-mediated Tyr-527-independent and Tyr-416-linked mechanism.

Akhand AA, Pu M, Senga T, Kato M, Suzuki H, Miyata T, Hamaguchi M and Nakashima I

J Biol Chem   Vol. 274 ( 36 ) page： 25821-25826   1999.9

Nitric oxide controls Src Kinase activity through a redox-based molecular modification.

Akhand AA, Pu M, Senga T, Kato M, Suzuki H, Miyata T, Hamaguchi M and Nakashima I

J Biol Chem   Vol. 274 ( 36 ) page： 25821-25826   1999.9

Biological and biochemical properties of Ret with kinase domain mutations identified in multiple endocrine neoplasia type 2B and familial medullary thyroid carcinoma.

Iwashita T, Kato M, Murakami H, Asai N, Ishiguro Y, Ito S, Iwata Y, Kawai K, Asai M, Kurokawa K, Kajita H and Takahashi M

Oncogene   Vol. 18 ( 26 ) page： 3919-3922   1999.7

4-Hydroxynonenal triggers epidermal growth factor receptor-linked signal for growth inhibition.

Liu W, Akhand AA, Kato M, Yokoyama I, Uchida K, Miyata T, Kurokawa K and Nakashima I

J Cell Sci   Vol. 112 ( Pt 14 ) page： 2409-2417   1999.7

Serum soluble Fas levels as a marker to distinguish allergic and non- allergic rhinitis.

Kato M, Hattori T, Ito H, Kageyama M, Yamashita T, Nitta Y and Nakashima I

J Allergy Clin Immunol   Vol. 103 ( 6 ) page： 1213-1214   1999.6

Elevated soluble tumor necrosis factor receptors levels in seasonal allergic rhinitis patients.

Kato M, Hattori T, Kato Y, Matsumoto Y, Yamashita T and Nakashima I

Allergy   Vol. 54 ( 3 ) page： 278-282   1999.3

Linkage between melanocytic tumor development and early burst of Ret protein expression for tolerance induction in metallothionein-I/ret transgenic mouse lines.

Kato M, Liu W, Akhand AA, Dai Y, Ohbayashi M, Tuzuki T, Suzuki H, Isobe K-I, Takahashi M and Izumi Nakashima

Oncogene   Vol. 18 ( 3 ) page： 837-842   1999.1

Carbonyl compounds cross-link cellular proteins and activate protein-tyrosine kinase p60c-Src.

Akhand AA, Kato M, Suzuki H, Liu W, Du J, Hamaguchi M, Miyata T, Kurokawa K and Nakashima I

J Cell Biochem   Vol. 72 ( 1 ) page： 1-7   1999.1

Differential regulation of MMP-9 and TIMP-2 expression in malignant melanoma developed in metallothionein/RET transgenic mice.

Asai M, Kato M, Asai N, Iwashita T, Murakami H, Kawai K, Nakashima I and Takahashi M

Jpn J Cancer Res   Vol. 90 ( 1 ) page： 86-92   1999.1

Mercuric chloride induces increases in both cytoplasmic and nuclear free calcium ions through a protein phophorylation-linked mechanism.

Parashar A, Akhand AA, Rawar R, Furuno T, Nakanishi M, Kato M, Suzuki H and Nakashima I

Free Radical Bio Med   Vol. 26 ( 1-2 ) page： 227-231   1999.1

Induction of T lymphocyte apoptosis by the treatment with glycyrshizing.

Oh C, Kim Y, Eun J, Yokoyama N, Kato M and Nakashima I

Am J Chinese Med.   Vol. 27 ( 2 ) page： 217-226   1999

Oxidative stress and signal transduction in the immune system. Recent Res Devel Immunology

Nakashima I, Akhand AA, Kato M, Du J, Liu W, Hossain K, Suzuki H, Wu J, Takeda K, Takeuchi K and Yoshihara M

Recent Res Devel Immunology   Vol. 1   page： 283-296   1999

Magnitude of HgCl₂-mediated phosphorylation of intracellular proteins determines death of thymic T-lymphocytes with or without DNA fragmenatation.

Akhand AA, Kato M, Suzuki H, Miyata T and Nakashima I

J Cell Biochem   Vol. 71 ( 2 ) page： 243-253   1998.11

Transgenic Mouse Model for Skin Malignant Melanoma.

Kato M, Takahashi M, Akhand Anwarul A, Liu W, Dai Y, Shimizu S, Iwamoto T,

Oncogene   Vol. 17 ( 14 ) page： 1885-1888   1998.10

The herbal medicine Sho-saiko-to inhibits growth and metastasis of malignant melanoma primarily developed in ret-transgenic mice.

Kato M, Liu W, Yi H, Asai N, Hayakawa A, Kozaki K-I, Takahashi M and Nakashima I

J Invest Dermatol   Vol. 111 ( 4 ) page： 640-644   1998.10

Elevated soluble Fas levels in herpes zoster patients.

Kato M, Tamada Y, Kageyama M, Yamashita T, Nitta Y, Ikeya T and Nakashima I

Brit J Dermatol   Vol. 138 ( 6 ) page： 1091   1998.6

The herbal medicine sho-saiko-to inhibits the growth of malignant melanoma cells by upregulating Fas-mediated apoptosis and arresting cell cycle through downregulation of cyclin dependent kinases.

Liu W, Kato M, Akhand AA, Hayakawa A, Takemura M, Yoshida S, Suzuki H, and Nakashima I

Int J Oncol   Vol. 12 ( 6 ) page： 1321-1326   1998.6

Evidence of potential regulation by interleukin 4 of the soluble intercellular adhesion molecule-1 level in patients with seasonal allergic rhinitis under provocation by a small amount of natural allergen.

Kato M, Hattori T, Liu W and Nakashima I

Ann Oto Rhinol Laryn   Vol. 107 ( 3 ) page： 232-235   1998.3

Protein Kinase C α-Mediated Chronic Signal Transduction for Immunosenescence.

Ohkusu K, Du J, Isobe K, Yi H, Akhand AA, Kato M, Suzuki H, Hidaka H and Nakashima I

J Immunol   Vol. 159 ( 5 ) page： 2082-2084   1997.9

Chemical events in signal transduction.

Nakashima I, Pu M, Akhand AA, Kato M and Suzuki H

Immunol Today   Vol. 18 ( 7 ) page： 362   1997.7

Magnitude of protein tyrosine phosphorlyation-linked signals determines growth versus death of thymic T lymphocytes.

Akhand AA, Pu M, Du J, Kato M, Suzuki H, Hamaguchi M and Nakashima I

Eur J Immunol   Vol. 27 ( 5 ) page： 1254-1259   1997.5

Enhancement of interleukin-1 alpha mediated autocrine growth of cultured human keratinocytes by Sho-saiko-to.

Matsumoto Y, Kato M, Tamada Y and Ohashi M

Jpn J Pharmacol   Vol. 73 ( 4 ) page： 333-336   1997.4

Differential sensitivities to hyperbaric oxygen of lymphocyte subpopulations of normal and autoimmune mice.

Xu X, Yi H, Kato M, Suzuki H, Kobayashi S, Takahashi H and Nakashima I

Immunol Lett   Vol. 59   page： 79-84   1997

Dynamics of soluble adhesion molecules level in the patients with pollinosis.

Kato M, Hattori T, Matsumoto Y and Nakashima I

Arch Otolaryngol Head Neck Surg   Vol. 122 ( 12 ) page： 1398-1400   1996.12

Evidence of a novel redox-linked activation mechanism for the Src kinase which is independent of tyrosine 527-mediated regulation.

Pu M, Akhand AA, Kato M, Hamaguchi M, Koike T, Sabe S, Suzuki H and

Oncogene   Vol. 13 ( 12 ) page： 2615-22   1996.12

Mercuric chloride mediates a protein sulfhydyl modification-based pathway of signal transduction for activating Src Kinase which is independent of the phosphorylation/dephosphorylation of a carboxyl terminal tyrosine

Pu M, Akhand AA, Kato M, Koike T, Hamaguchi M, Suzuki H and Nakashima I

J. Cell Biochem.   Vol. 63 ( 1 ) page： 104-114   1996.10

Amount of pollen has an efect on the systemic and local levels of soluble ICAM-1 in patients with seasonal allergic shinitis

Kato M, Hattori T, Ikeda R, Yamamoto J, Yamashita T, Yanagita N and Nakashima I

Allergy   Vol. 51 ( 2 ) page： 128-132   1996.2

Major basic protein (MBP) and topical administration of ketotifen in pollinosis under natural allergen provocation.

Kato M, Hattori T, Kitamura M, Beppu R, Nakashima I and Yanagita N

OLR   Vol. 57 ( 5 ) page： 269   1995.9

Multiphasic modulation of signal transduction into T lymphocytes by monoiodoacetic acid as a sulfhydryl reagent.

Ma Li, Pu M, Yi H, Akhand AA, Ohata N, Ohkusu K, Kato M, Iwamoto T, Isobe K, Hamaguchi M and Nakashima I

J.Cell.Biochem.   Vol. 59 ( 1 ) page： 33-41   1995.9

Soluble ICAM-1 as a regulator of nasal allergic reaction under natural allergen provocation.

Kato M, Hattori T, Kitamura M, Beppu R, Yanagita N and Nakashima I

Cln.Exp.Allergy   Vol. 25 ( 8 ) page： 744   1995.8

Dissociated control by glycyrrhizin of proliferation and IL-2 production of murine thymocytes.

Zhang YH, Kato M, Isobe K, Hamaguchi M, Yokochi T and Nakashima I

Cell Immunol.   Vol. 162 ( 1 ) page： 97-104   1995.4

Oncogene-liked in situ immunotherapy of pre-B lymphoma arising in Eu/ret transgenic mice.

Ichihara M, Iwamoto T, Isobe K, Takahashi M, Nakayama A, Pu M, Parashar A, Ohkusu K, Kato M, Hotta T and Nakashima I

Brit J Cancer   Vol. 71 ( 4 ) page： 808-813   1995.4

Cell type-oriented differential modulatory actions of saikosaponin-d on growth responses and DNA fragmentation of lymphocytes thymic receptor-mediated and receptor-bypassed pathways.

Kato M, Pu M, Isobe K, Hattori T, Yanagita N, Nakashima I

Immunopharmacology   Vol. 29 ( 3 ) page： 207   1995.4

Promotion of cytotoxic T-cell generation in mixed leukocyte culture by phosphatidylinositol-specific phospholipase C from Bacillus Thuringiensis.

Rahman SMJ, Pu M, Hong Y, Ohkusu K, Kato M, Isobe K, Taguchi R, Ikezawa H and Nakashima I

Infect.Immunity   Vol. 63 ( 1 ) page： 259   1995.1

Characterization of the immunoragulatory action of saikosaponin-d.

Kato M, Pu M, Isobe K, Iwamoto T, Nagase F, Lwin T, Zhang YH, Hattori T, Yanagita N and Nakashima I

Cell Immunal   Vol. 159 ( 1 ) page： 15-25   1994.11

Eosinophil cationic protein (ECP) and prophylactic treatment in pollinosis in natural allergen rovocation.

Kato M, Hattori T, Takahashi M, Nakashima I and Yanagita N

Brit.J.Cln.Pract.   Vol. 48 ( 6 ) page： 299-301   1994.11

Pathway of signal delivery to murine thymocytes triggered by co-crosslinking CD3 and thy-1 for cellular DNA fragmentation and growth inhibition.

Nakashima I, Pu M, Hamaguchi M, Iwamoto T, Rahman SMJ, Zhang YH, Kato M,

J.Immunol.   Vol. 151 ( 7 ) page： 3511-20   1993.10

Glycyrrhizin as a promoter of the late signal transduction for interleukin-2 production by splenic lymphocytes.

Zhang YH, Isobe K, Nagase F, Lwin T, Kato M, Hamaguchi M and Nakashima I

Immunology   Vol. 79 ( 4 ) page： 528-534   1993.8

T cell maturation stage-linked heterogeneity of the glycosylphosphatidylinositol membrane anchor of thy-1.

Nakashima I, Yoshida T, Zhang YH, Pu M, Taguchi R, Ikezawa H, Isobe K, Iwamoto T,

Immunobiol   Vol. 185 ( 5 ) page： 466-474   1992.9

Prognostic factors in squamous cell carcinoma of the larynx.

Takahashi M, Avasarala JR, Kato M and Yanagita N

Auris Nasus Larynx   Vol. 19   page： S127-S133   1992

色素細胞（第2版）

山本博章, 大神信孝, 矢嶋伊知朗, 加藤昌志（ Role： Joint author）

慶応義塾大学出版会  2015 

悪性黒色腫の発癌機構（紫外線など環境因子との関係）

矢嶋伊知朗, 加藤昌志（ Role： Joint author）

株式会社　日本臨床社  2013 

モデル動物利用マニュアルシリーズ疾患モデルの作製と利用

加藤昌志, 高橋雅英（ Role： Joint author）

株式会社　エル・アイ・シー  2012 

免疫実験法ハンドブック

中島泉, 加藤昌志他（ Role： Joint author）

名古屋大学出版会  2006 

Systematic elucidation of various health disorders induced by low-frequency sound

Grant number：23K27837  2023.4 - 2027.3

Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)

皮革産業による環境汚染に起因する健康障害を解決する疫学・基礎融合研究

Grant number：22KK0145  2022.10 - 2027.3

科学研究費助成事業  国際共同研究加速基金(国際共同研究強化(B))

加藤 昌志, 田崎 啓, 大神 信孝, 原 田

Development of new technology for custom-made evaluation of health effects of oral exposure to elements

Grant number：19H01147  2019.4 - 2022.3

Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (A)

Kato Masashi

Development of a solution for environmental pollution caused by economic globalization

Grant number：17KT0033  2017.7 - 2024.3

Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)

Kato Masashi

Health risk assessment and development of remediation systems for elemental contamination of drinking water in Asian countries

Grant number：15H02588  2015.4 - 2019.3

Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (A)

Kato Masashi

Clarification of mechanisms and development of preventive methods for health disturbances caused by exposure to low frequency noise

Grant number：15H01743  2015.4 - 2019.3

Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (A)

Kato Masashi

Development of a novel molecular target therapy that can suppress melanoma progression

Grant number：26670525  2014.4 - 2018.3

Grants-in-Aid for Scientific Research  Grant-in-Aid for Challenging Exploratory Research

Masashi Kato, YAJIMA Ichiro

プラズマ医療のための気相・表界反応ダイナミクスの計測と体系化

2012.4 - 2017.3

科学研究費補助金  新学術領域研究

Advanced Occupational and Environmental Health Science

2020

Occupational and Environmental Health

2020

Occupational and Environmental Health

2020

Social Life Science

2020