研究者詳細 - 秋間　広

Effects of 10-week walking and walking with home-based resistance training on muscle quality, muscle size, an physical functional tests in healthy older individuals. 査読有り

Yoshiko, A., Tomita, A., Ando,. R., Ogawa, M., Kondo, S., Saito, A., Tanaka, N., Koike, T., Oshida, Y., Akima, H.

Eur. Rev. Aging Phys Act. 頁： 000-000 2018年

Relationship between quadriceps echo intensity and functional and morphological characteristics in older men and women 査読有り Open Access

Akima, H., Yoshiko, A., Tomita, A., Ando, R., Saito, A., Ogawa, M., Kondo, S., Tanaka, N.I.

Arch. Gerontol. Geriatr. 70 巻頁： 105-111 2017年2月

Three-dimensional comparison of intramuscular fat content between young and old adults 査読有り Open Access

Yoshiko A, Hioki M, Kanehira N, Shimaoka K, Koike T, Sakakibara H, Oshida Y, Akima H.

BMC Med Imaging 10 巻頁： 17 2017年2月

Three-dimensional comparison of intramuscular fat content between young and old adults 査読有り Open Access

Yoshiko, A., Hioki, M., Kanehira, N., Shimaoka, K., Koike, T., Sakakibara, H., Oshida, Y., Akima, H.

BMC Medical Imaging 17 巻頁： 12 2017年1月

Effects of prolonged vibration to vastus intermedius muscle on force steadiness of knee extensor muscles during isometric force-matching task 査読有り

Saito, A., Ando, R., Akima, H.

J. Electromyogr. Kinesiol. 2016年12月

Associations of intramyocellular lipid in vastus lateralis and biceps femoris with blood free fatty acid and muscle strength differ between young and elderly adults. 査読有り Open Access

Hioki M, Kanehira N, Koike T, Saito A, Takahashi H, Shimaoka K, Sakakibara H, Oshida Y, Akima H.

Clin Physiol Funct Imaging 36 巻 ( 6 ) 頁： 457-463 2016年11月

Neuromuscular Activation of the Vastus Intermedius Muscle during Isometric Hip Flexion. 査読有り Open Access

Saito A, Akima H.

PLoS One 10 巻 ( 10 ) 頁： e0141146 2016年10月

Age-related changes in motor unit firing pattern of vastus lateralis muscle during low-moderate contraction. 査読有り Open Access

Watanabe K, Holobar A, Kouzaki M, Ogawa M, Akima H, Moritani T

Age (Dordr) 38 巻 ( 3 ) 頁： 48 2016年6月

Intramuscular adipose tissue determined by T1-weighted MRI at 3T primarily reflects extramyocellular lipids. 査読有り

Akima H, Hioki M, Yoshiko A, Koike T, Sakakibara H, Takahashi H, Oshida Y.

Magn Reson Imaging 34 巻 ( 4 ) 頁： 397-403 2016年5月

Effects of prolonged patellar tendon vibration on force steadiness in quadriceps femoris during force-matching task 査読有り

Saito, A., Ando, R., Akima, H.

Exp. Brain Res. 234 巻 ( 1 ) 頁： 209-217 2016年1月

Effect of interelectrode distance on surface electromyographic signals of vastus intermedius muscle in women and men 査読有り

Tomita, A., Ando, R., Saito, A., Watanabe, K.,Akima, H.

J. Electromyogr. Kinesiol. 25 巻頁： 841-846 2015年12月

Non-uniform recruitment along humans rectus femmoris muscle during transcutaneous electrical nerve stimulation. 査読有り

Watanabe, K., Kouzaki, M., Ando, R., Akima, H., Moritani, T.

Eur. J. Appl. Phsyiol. 115 巻頁： 2159-2165 2015年6月

Skeletal muscle size is a major predictor of intramuscular fat content regardless of age 査読有り

Akima, H., Yoshiko, A., Hioki, M., Kanehira, N., Shimaoka, K., Koike, T., Sakakibara, H., Oshida, Y.

Eur. J. Appl. Physiol. 頁： 000-000 2015年

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

Purpose
Skeletal muscles of older individuals have a larger amount of intramuscular adipose tissue (IntraMAT) than those of younger individuals. It is not understood how aging affects the IntraMAT content of individual muscles of the thigh. We assessed the relationship between IntraMAT content and skeletal muscle cross-sectional area (CSA), subcutaneous adipose tissue CSA, biochemical blood profiles, and physical activity.
Methods
Fifteen older (70.7 ± 3.8 years) and 15 younger (20.9 ± 0.3 years) men and women participated in this study. Magnetic resonance imaging of the right thigh was taken to measure IntraMAT content and skeletal muscle CSA for the quadriceps femoris (QF), hamstrings (HM), adductor (AD) muscle groups and subcutaneous adipose tissue CSA of the thigh. Fasting blood samples were collected to measure plasma lipids, adiponectin, and HbA1c levels.
Results
IntraMAT content in QF, HM, and AD for the Older group was significantly higher than in the Younger group. However, skeletal muscle CSA normalized by body weight (skeletal muscle CSA/bw) in the QF (P < 0.001) and total thigh (P < 0.01) were significantly lower in the Older group compared with the Younger group.There were no significant differences in HM and AD. Stepwise regression analysis with IntraMAT content as a dependent variable revealed that skeletal muscle CSA/bw of the thigh was the only predictive variable for IntraMAT content in Older and Younger groups.
Conclusion
These results suggest that skeletal muscle size could be a major determinant of IntraMAT content regardless of age.

DOI： 10.1007/s00421-015-3148-2

Effects of prolonged patellar tendon vibration on force steadiness in quadriceps femoris during force-matching task. 査読有り

Saito, A., Ando, R., Akima, H.

Exp. Brain Res. 頁： 00-00 2015年

Difference in fascicle behaviors between superficial and deep quadriceps muscles during isometric contractions 査読有り

Difference in fascicle behaviors between superficial and deep quadriceps muscles during isometric contractions.

Muscle & Nerve 999 巻 ( 999 ) 頁： 999-999 2015年

Coordination among thigh muscles including the vastus intermedius and adductor magnus at different cycling intensities. 査読有り

Saito, A., Akima, H.

Human Mov. Sci. 頁： 000-000 2014年12月

Validity of fascicle length estimation in the vastus lateralis and vastus intermedius using ultrasonography 査読有り

Ando, R., Taniguchi, K., Saito, A., Fujimiya, M., Katayose, M., Akima, H.

J. Electromyogr. Kinesiol. 24 巻頁： 214-220 2014年7月

Estimation of muscle atrophy based on muscle thickness in knee surgery patients 査読有り

Hioki, M., Furukawa, T., Akima, H.

Clin. Physiol. Funct. Imaging 34 巻頁： 183-190 2014年7月

Local architecture of the vastus intermedius is a better predictor of knee extension force than that of the other quadriceps femoris muscle heads. 査読有り

Ando, R., Saito, A., Umemura, Y., Akima, H.

Clin. Physiol. Func. Imaging 9999 巻頁： 9999 2014年6月

Coordination among thigh muscles including the vastus intermedius and adductor magnus at different cycling intensities. 査読有り

Saito, A., Watanabe, K., Akima, H.

Human Mov. Sci. 頁： 000-000 2014年

Activation of quadriceps femoris including vastus intermedius during fatiguing dynamic knee extensions 査読有り

Akima, H., Saito, A.

Eur. J. Appl. Physiol. 113 巻頁： 2829-2840 2013年9月

Estimation of muscle atrophy based on muscle thickness in knee surgery patients 査読有り

Hioki, M., Fufukawa, T., Akima, H.

Clin. Physiol. Funct. Imaging 2013年9月

Knee joint angle affects EMG-force relationship in the vastus intermedius muscle 査読有り

Saito, A., Akima, H.

J. Electromyogr. Kinesiol. 23 巻頁： 1406-1412 2013年9月

The highest antagonistic coactivation of the vastus intermedius muscle among quadriceps femoris muscles during isometric knee flexion. 査読有り

Saito, A., Akima, H.

J. Electromyogr. Kinesiol. 頁： 000 2013年5月

Inverse activation between the deeper vastus intermedius and superficial muscles in quadriceps during dynamic knee extensions 査読有り

Akima, H., Saito, A.

Muscle & Nerve 47 巻頁： 682-690 2012年12月

Evaluation of functional properties of skeletal muscle using functional magnetic resonance imaging 招待有り

Akima, H.

J. Phys. Fitness Sports Med. 1 巻頁： 621-630 2012年12月

Alternate muscle activity patterns among synergists of the quadriceps femoris including the vastus intermedius during low-level sustained contraction in men 査読有り

Akima, H., Saito, A.

Muscle & Nerve 2012年3月

Relationships of thigh muscle contractile and non-contractile tissue with function, strength, and age in boys with Duchenne muscular dystrophy. 査読有り Open Access

Akima, H., Lott, D., Senesac, C., Deol, J., Gemain, S., Arpan, I., Bendixen, R., Walter, G., Vandenborne, K.

Neuromuscul. Disord. 22 巻頁： 16-25 2012年1月

Alternate muscle activity patterns among synergists of the quadriceps femoris including the vastus intermedius during low-level sustained contraction in men. 査読有り

Akima, H., Saito, A., Watanabe, K., Kouzaki, M.

Muscle & Nerve in pres 巻頁： 00-000 2011年12月

The effect of intense interval cycling-training on unloading-induced dysfunction and atrophy in the human calf muscle. 査読有り

Hotta, N., Ishida, K., Sato, K., Watanabe, K., Katayama, K., Akima, H.

J. Physiol. Anthropol. 30 巻頁： 29-35 2011年

Effect of knee joint angle on neuromuscular activation of the vastus intermedius muscle during isometric contraction. 査読有り

Watanabe, K., Akima, H.

Scand. J. Med. Sci. Sports 頁： 000-000 2011年

Validity of surface electromyography for vastus intermedius muscle assessed by needle electromyography. 査読有り

Watanabe, K., Akima, H.

J. Neurosci. Methods 198 巻頁： 332-335 2011年

Relationship between aerobic capacity and muscle atrophy after lower limbs suspension with and without countermeasure. 査読有り

Sato, K., Hotta, N., Miyachi, M., Masuda, K., Koike, T., Akima, H.

Aviat. Space Environ Med. 30 巻頁： 1085-1091 2010年

Effects of deconditioning on the initial ventilatory and circulatory responses at the onset of exercise in man. 査読有り

Ishida, K., Katayama, K., Akima, H., Iwase, S., Sato, K., Hotta, N., Miyamura, M

Adv. Exp. Med. Biol. 669 巻頁： 319-322 2010年

Neuromuscular activation of vastus intermedius muscle during fatiguing exercise. 査読有り

Watanabe, K., Akima, H.

J. Electromyogr. Kinesiol. 20 巻頁： 661-666 2010年

Muscle deoxygenation during sustained and intermittent isometric exercise in hypoxia. 査読有り

Katayama, K., Yoshitake, Y., Watanabe, K., Akima, H., Ishida, K.

Med. Sci. Sports Exerc. 42 巻頁： 1269-1278 2010年

Cycle ergometer exercise counteract muscle atrophy during unilateral lower limb suspension. 査読有り

Akima, H., Hotta, N., Sato, K., Ishida, K., Koike, T., Katayama, K.

Aviat. Space Environ. Med. 80 巻頁： 652-656 2009年

*Cross-talk from adjacent muscle has a negligible effect on surface electromyographic activity of vastus intermedius muscle during isometric contraction.

Watanabe, K, Akima, H.

J. Electromyogr. Kinesiol. 19 巻頁： e280-e289 2009年

The adaptive responses in several mediators linked with hypertrophy and atrophy of skeletal muscle after lower limb unloading in humans. 査読有り

Sakuma, K., Watanabe, K., Hotta, N., Koike, T., Ishida, K., Katayama, K., Akima, H

Acta Physiol. 197 巻頁： 151-159 2009年

Electromyographic analysis of hip adductor muscles during incremental fatiguing pedaling exercise. 査読有り

Watanabe, K., Katayama, K., Ishida, K., Akima, H.

Eur. J. Appl. Physiol. 106 巻頁： 815-825 2009年

*Effect of arthroscopic partial meniscectomy on the function of quadriceps femoris. 査読有り

Akima, H., Hioki, M., Furukawa, T.

Knee Surg. Sports Traumatol. Arthrosc. 16 巻頁： 1017-1025 2008年

Age-related reductions in expression of serum response factor and myocardin-related transcription factor A in mouse skeletal muscles. 査読有り Open Access

Sakuma, K., Akiho, M., Nakashima, H., Akima, H., Yasuhara, M.

Biochimica Biophysica Acta 1782 巻頁： 453-461 2008年

Effect of unweighting on muscle volume with and without resistance training. 査読有り

Akima, H., Ushiyama, J., Kubo, J., Fukuoka, H., Kanehisa, H., Fukunaga, T.

Acta Astronaut 60 巻頁： 728-736 2007年

Thigh muscle activation distribution and pulmonary Vo2 kinetics during moderate, heavy and severe intensity cycling exercise in humans. 査読有り

Yamaoka-Endo, M., Kobayakawa, M., Kinugasa, R., Kuno, S., Akima, H., Rossiter, H. B., Miura, A., Fukuba, Y.

Am. J. Physiol. Regul. Comp. Physiol. 293 巻頁： R812-R820 2007年

Effects of 20-day bed rest with and without strength training on postural sway during quite standing. 査読有り

Kouzaki, M., Masani, K., Akima, H., Shirasawa, H., Fukuoka, H., Kanehisa, H., Fukunaga, T.

Acta Physiol. 183 巻頁： 279-292 2007年

Ubiquitin ligase gene expression in healthy volunteers with 20-day bedrest. 査読有り

Ogawa, T., Furochi, H., Mameoka, M., Hirasaka, K., Suzue, N., Oarada, M., Akamatsu, M., Akima, H., Fukunaga, T., Kishi, K., Yasui, N., Fukuoka, H., Nikawa, T.

Muscle & Nerve 34 巻頁： 463-469 2006年

Muscle soreness and damage augment ventilatory response at the onset of exercise 査読有り

Hotta, N., Sato, K., Sun, Z., Katayama, K., Akima, H., Kondo, T., Ishida, K.

Eur. J. Appl. Phjysiol. 97 巻頁： 598-606 2006年

Atrophy of thigh muscles after meniscal lesions and arthroscopic partial meniscectomy. 査読有り

Knee Surg. Sports Traumatol. Arthrosc. 13 巻頁： 632-637 2005年

Recruitment of the thigh muscles during sprint cycling by muscle functional magnetic resonance imaging. 査読有り

Akima, H., Kinugasa, R., Kuno, S.

Int. J. Sports Med. 26 巻頁： 245-252 2005年

Functional imaging of human skeletal muscle during movement: Implication for recruitment, metabolism and circulation. 招待有り査読有り Open Access

Akima, H.

Int. J. Sport Health Sci. 3 巻頁： 193-206 2005年

Intensive cycle training with artificial gravity maintains muscle size during bed rest. 査読有り

Akima, H., Katayama, K., Sato, K., Ishida, K., Masuda, K., Takada, H., Watanabe, Y., Iwase, S.

Aviat. Space Environ. Med. 76 巻頁： 923-929 2005年

Neuromuscular activation of triceps surae using muscle functional MRI and EMG. 査読有り

Kinugasa, R., Akima, H.

Med. Sci. Sports Exerc 37 巻頁： 593-598 2005年

Effects of 20 days of bed rest on the viscoelastic properties of tendon structures in lower limb muscles. 査読有り Open Access

Kubo, K., Akima, H., Ushiyama, J., Tabata, I., Fukuoka, H., Kanehisa, H., Fukunaga, T.

Br. J. Sports Med. 38 巻頁： 324-330 2004年

Effects of bed rest deconditioning on ventilatory and cardiovascular responses to hypoxia and hypercapnia. 査読有り

Katayama, K., Sato, K., Akima, H., Ishida, K., Yanagiya, T., Kanehisa, H., Fukuoka, H., Fukunaga, T., Miyamura, M.

Aviat. Space Environ. Med. 75 巻頁： 312-316 2004年

Short-term creatine supplementation does not improve muscle activation or sprint performance in humans. 査読有り

Kinugasa, R., Akima, H., Ota, A., Ohta, A., Sugiura, K., Kuno, S.

Eur. J. Appl. Physiol. 91 巻頁： 230-237 2004年

Coactivation pattern in human quadriceps during isokinetic knee-extension by muscle functional MRI. 査読有り

Akima, H., Takahashi, H., Kuno, S., Katsuta, S.

Eur. J. Appl. Physiol. 91 巻頁： 7-14 2004年

Acceleration with exercise during head-down bed rest preserves upright exercise responses. 査読有り

Katayama, K., Sato, K., Akima, H., Ishida, K., Takada, H., Watanabe, Y., Iwase, M., Miyamura, M., Iwase, S.

Aviat. Space Environ. Med. 75 巻頁： 1029-1035 2004年

Human adductor muscle atrophy after short duration of unweighting. 査読有り

Kawashima, S., Akima, H., Kuno, S., Gunji, A., Fukunaga, T.

Eur. J. Appl. Physiol. 92 巻頁： 602-605 2004年

Effects of resistance training during bed rest on the viscoelastic properties of tendon structures in the lower limb. 査読有り

Kubo, K., Akima, H., Ushiyama, J., Tabata, I., Fukuoka, H., Kanehisa, H., Fukunaga, T.

Scan. J. Med. Sci. Sports 14 巻頁： 296-302 2004年

Resistance training during unweighting maintains muscle size and function in human calf. 査読有り

Akima, H., Ushiyama, J., Kubo, J., Tonosaki, S., Itoh, M., Kawakami, Y., Fukuoka, H., Kanehisa, H., Fukunaga, T.

Med. Sci. Sports Exerc. 35 巻頁： 655-662 2003年

Vastus lateralis fatigue alters recruitment of musclus quadriceps femoris in humans. 査読有り

Akima, H., Foley, J.M., Prior, B.M., Dudley, G.A., Meyer, R.A.

J. Appl. Physiol. 92 巻頁： 679-684 2002年

Inactivity and muscle: effect of resistance training during bed rest on muscle size in the lower limb. 査読有り

Akima, H., Kubo, K., Imai, M., Kanehisa, H., Suzuki, Y., Gunji, A., Fukunaga, T.

Acta Physiol. Scand. 172 巻頁： 269-278 2001年

Muscle function in 164 men and women aged 20-84 yr. 査読有り

Akima, H., Kano, Y., Enomoto, Y., Ishizu, M., Okada, M., Ohishi, Y., Katsuta, S., Kuno, S.

Med. Sci. Sports Exerc. 33 巻頁： 220-226 2001年

*Leg-press training during 20 days of 6 head-down-tilt bed rest prevents muscle deconditioning. 査読有り

Akima, H., Kubo, K., Kanehisa, H., Suzuki, Y., Gunji, A., Fukunaga, T.

Eur. J. Appl. Physiol. 82 巻頁： 30-38 2000年

The use of magnetic resonance images to investigate the influence of recruitment on the relationship between torque-cross-sectional area in human muscle. 査読有り

Akima, H., Kuno, S., Takahashi, H., Fukunaga, T., Katsuta, S.

Eur. J. Appl. Physiol. 83 巻頁： 475-480 2000年

*Effect of short-duration spaceflight on thigh and leg muscle volume. 査読有り

Akima, H., Kawakami, Y., Kubo, K., Sekiguchi, C., Ohshima, H., Miyamoto, A., Fukunaga, T.

Med. Sci. Sports Exerc. 32 巻頁： 1743-1747 2000年

Recruitment plasticity of neuromuscular compartments in exercising tibialis anterior using echo-planar magnetic resonance imaging in humans. 査読有り

Akima, H., Ito, M., Yoshikawa, H., Fukunaga, T.

Neurosci. Lett. 296 巻頁： 133-136 2000年

*Early phase adaptations of muscle use and strength to isokinetic training. 査読有り

Akima, H., Takahashi, H., Kuno, S., Masuda, K., Masuda, T., Shimojo, H., Anno, I., Itai, Y., Katsuta, S.

Med. Sci. Sports Exerc. 31 巻頁： 588-594 1999年

Effects of 20 days of bed rest on physiological cross-sectional area of human thigh and leg muscles evaluated by magnetic resonance imaging. 査読有り

Akima, H., Kuno, S., Suzuki, Y., Gunji, A., Fukunaga, T.

J. Gravitat. Physiol. 4 巻頁： S15-S22 1997年

Effects of sprint cycle training on architectural characteristics, torque-velocity relationships, and power output in human skeletal muscles. 査読有り

Akima, H., Kuno, S., Inaki, M., Shimojo, H., Katsuta, S.

Adv. Exerc. Sports Physiol. 3 巻頁： S9-S15 1997年

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