Updated on 2025/04/12

写真a

 
OOI Takashi
 
Organization
Institute of Transformative Bio-Molecules Professor
Graduate School
Graduate School of Engineering
Title
Professor
External link

Degree 1

  1. Ph.D. ( 1994.3   Nagoya University ) 

Research Areas 1

  1. Others / Others  / Synthetic Chemistry

Current Research Project and SDGs 1

  1. 有機イオン対の分子設計に基づく触媒機能の創出

Research History 8

  1. Institute of Transformative Bio-Molecules (ITbM) Professor

    2013.4

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    Country:Japan

  2. Professor (Nagoya University)

    2006.5

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  3. Associate Professor (Kyoto University)

    2001.1 - 2006.4

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    Country:Japan

  4. Lecturer (Hokkaido University)

    1998.6 - 2000.12

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    Country:Japan

  5. Assistant Professor (Hokkaido University)

    1995.6 - 1998.5

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    Country:Japan

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Education 2

  1. Nagoya University   Graduate School, Division of Engineering   Department of Applied Chemistry

    1991.4 - 1994.3

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    Country: Japan

  2. Nagoya University   Graduate School, Division of Engineering   Department of Applied Chemistry

    1989.4 - 1991.3

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    Country: Japan

Professional Memberships 3

  1. Chemical Society of Japan

  2. The Society of Synthetic Organic Chemistry, Japan

  3. American Chemical Society

Committee Memberships 4

  1. 独立行政法人日本学術振興会学術システム研究センター   専門研究員  

    2023.4 - 2026.3   

  2. 井上科学振興財団   選考委員会委員  

    2022.4   

  3. 有機合成化学協会   東海支部支部長  

    2021.3 - 2023.2   

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    Committee type:Academic society

  4. 日本学術振興会   先端科学シンポジウム事業委員  

    2020.4   

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    Committee type:Government

Awards 11

  1. 有機合成化学協会研究企画賞

    1996   有機合成化学協会  

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    Country:Japan

  2. 日本化学会進歩賞

    1999   日本化学会  

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    Country:Japan

  3. Theme Journal Award

    2006   Theme  

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    Country:Japan

  4. 日本学術振興会賞

    2011.3   日本学術振興会  

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    Country:Japan

  5. 第25回日本IBM科学賞

    2011.11   日本IBM  

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    Country:Japan

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Papers 203

  1. Photocatalytic carbyne reactivity of phosphorus ylides for three-component formal cycloaddition reactions Reviewed International coauthorship

    Ryuhei Suzuki, Taiga Ando, Fritz Deufel, Kohsuke Ohmatsu, and Takashi Ooi

    Nature Synthesis   Vol. 3   page: 1385 - 1391   2024.7

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s44160-024-00612-7

  2. p-Diarylboryl Halothiophenols as Multifunctional Catalysts via Photoactive Intramolecular Frustrated Lewis Pairs Reviewed Open Access

    Takeru Kikura, Yuya Taura, Yoshitaka Aramaki, and Takashi Ooi

    Journal of the American Chemical Society   Vol. 146 ( 29 ) page: 20425 - 20431   2024.7

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/jacs.4c06122

    Open Access

  3. Zwitterionic Acridinium Amidate: A Nitrogen-Centered Radical Catalyst for Photoinduced Direct Hydrogen Atom Transfer Reviewed International coauthorship Open Access

    Lukas Entgelmeier, Soichiro Mori, Shion Sendo, Rie Yamaguchi, Ryuhei Suzuki, Takeshi Yanai, Olga García Mancheño, Kohsuke Ohmatsu, and Takashi Ooi

    Angewandte Chemie International Edition   Vol. 63 ( 43 ) page: e202404890   2024.6

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/anie.202404890

    Open Access

  4. If the Crown Fits: Sterically Demanding N-Heterocyclic Carbene Promotes the Formation of Au8Pt Nanocluster Reviewed International coauthorship

    Joseph F. DeJesus, Samuel I. Jacob, Quan Manh Phung, Koichi Mimura, Yoshitaka Aramaki, Takashi Ooi, Masakazu Nambo, Cathleen M. Crudden

    Journal of the American Chemical Society   Vol. 146 ( 34 ) page: 23806 - 23813   2024.8

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    Authorship:Corresponding author   Language:English  

    DOI: 10.1021/jacs.4c04873

  5. Catalytic 1,1-Cyanoalkylation of Electron-Deficient Olefins Reviewed

    Kohsuke Ohmatsu, Duc An Truong, Shohei Morita, Keiji Maruoka, and Takashi Ooi

    Organic Letters   Vol. 26 ( 19 ) page: 4055 - 4058   2024.5

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acs.orglett.4c00866

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Books 27

  1. Supramolecular Catalysis: New Directions and Developments Reviewed

    Kohsuke Ohmatsu, Daisuke Uraguchi, Takashi Ooi( Role: Contributor ,  Assembled Ionic Molecular Catalysts and Ligands)

    Wiley‐VCH  2022.1 

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    Total pages:614   Responsible for pages:41-53   Language:English Book type:Scholarly book

  2. Anion-Binding Catalysis Reviewed

    Kohsuke Ohmatsu,Takashi Ooi( Role: Contributor ,  1,2,3-Triazoles and 1,2,3-Triazolium Ions as Catalysts)

    Wiley-VCH  2021.3 

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    Language:English Book type:Scholarly book

  3. Organic Molecular Catalysts in Radical Chemistry: Challenges Toward Selective Transformations

    Daisuke Uraguchi, Kohsuke Ohmatsu, Takashi Ooi( Role: Joint author)

    2019 

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    Language:English Book type:Scholarly book

  4. 多機能型キラルオニウム塩の設計に基づく高選択的分子変換

    大松 亨介, 浦口 大輔, 大井 貴史( Role: Joint author)

    シーエムシー出版  2018 

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    Language:Japanese Book type:Scholarly book

    有機分子触媒の開発と工業利用

  5. Site-Selective Conjugate Addition through Catalytic Generation of Ion-Pairing Intermediates

    ( Role: Joint author)

    2016 

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    Language:English Book type:Scholarly book

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MISC 8

  1. Catalytic acceptorless dehydrogenative coupling mediated by photoinduced hydrogen-atom transfer Invited Reviewed

    Kohsuke Ohmatsu, Takashi Ooi

    Nature Synthesis   Vol. 2   page: 209 - 216   2023.1

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    Authorship:Corresponding author   Language:English   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

    DOI: 10.1038/s44160-022-00195-1

  2. Catalysis of chiral iminophosphorane for simultaneous control of multiple selectivity: experimental and theoretical investigation Reviewed

        2021.5

  3. Cationic Organic Catalysts or Ligands in Concert with Metal Reviewed

    Kohsuke Ohmatsu,Takashi Ooi

    Topics in Current Chemistry     2019.10

  4. Chemistry of Ammonium Betaines: Application to Ion-Pair Catalysis for Selective Organic Transformations Reviewed

    Journal of Synthetic Organic Chemistry, Japan     2018.11

  5. Development of Ion-Paired Chiral Ligands for Asymmetric Transition-Metal Catalysis Reviewed

        2015.3

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Presentations 62

  1. Toward Catalytic Control of Photoinduced Radical Reactions Invited International conference

    Takashi Ooi

    Stereochemisty Gordon Research Conference  2024.7.22  Gordon Research Conference

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    Event date: 2024.7

    Language:English   Presentation type:Oral presentation (invited, special)  

    Venue:Salve Regina University, Rhode Island   Country:United States  

  2. Development of Multifunctional Organic Photocatalysts Invited International conference

    Takashi Ooi

    1st Maruoka Conference at GDUT on the Frontier of Organic Synthesis and Catalysis  2025.1.17  GDUT

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    Event date: 2025.1

    Language:English   Presentation type:Oral presentation (invited, special)  

    Venue:GDUT, Guangzhou   Country:China  

  3. 光駆動ラジカル反応の触媒的な制御 Invited

    2024.10.24 

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    Event date: 2024.10

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  4. Development of Multifunctional Photocatalysts Invited International conference

    Takashi Ooi

    8th UK-Japan Catalysis Meeting  2024.9.26  Green Catalysis Science

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    Event date: 2024.9

    Language:English   Presentation type:Oral presentation (invited, special)  

    Venue:Kyoto University   Country:Japan  

  5. 光駆動ラジカル反応の触媒的な制御 Invited

    2024.9.20 

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    Event date: 2024.9

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

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Research Project for Joint Research, Competitive Funding, etc. 6

  1. アミノ酸誘導体を用いた農業資材に関する研究

    2024.1 - 2024.12

    共同研究  共同研究

    大井 貴史

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    Authorship:Principal investigator  Grant type:Collaborative (industry/university)

    Grant amount:\1430000 ( Direct Cost: \1100000 、 Indirect Cost:\330000 )

  2. 直截的分子変換を担う多機能光ラジカル触媒の創製

    2021.4 - 2023.3

    内藤記念科学奨励金・研究助成 

    大井 貴史

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    Authorship:Principal investigator  Grant type:Other

    Grant amount:\3000000 ( Direct Cost: \3000000 )

  3. ルイスラジカルイオン対の触媒化学

    Grant number:19H00894  2019.4 - 2022.3

    科学研究費補助金   基盤研究(A)

    大井 貴史

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\45500000 ( Direct Cost: \35000000 、 Indirect Cost:\10500000 )

  4. ハイブリッド触媒系による立体分岐型不斉合成

    Grant number:17H06446  2017.6 - 2022.3

    科学研究費補助金   新学術領域研究(研究領域提案型)

    大井貴史

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\144950000 ( Direct Cost: \111500000 、 Indirect Cost:\33450000 )

  5. Development of Molecular Technology for Ideal Chemical Transformations

    2013.10 - 2019.3

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    Grant type:Competitive

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KAKENHI (Grants-in-Aid for Scientific Research) 12

  1. イオン対ラジカル触媒の創製に基づく選択的分子変換法の開発

    Grant number:23K17914  2023.6 - 2025.3

    科学研究費助成事業  挑戦的研究(萌芽)

    大井 貴史

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    Authorship:Principal investigator 

    Grant amount:\6500000 ( Direct Cost: \5000000 、 Indirect Cost:\1500000 )

    静電的な相互作用などの非共有結合性の相互作用を利用したイオン性化学種の反応性や立体化学の制御とは全く異なり、ラジカル種の発生および結合形成の各段階を制御するための信頼性と汎用性を備えた触媒的な方法論はほとんど確立されていない。本研究では、水素原子移動触媒と基質認識を担う分子触媒に電荷を附与しイオン対型ラジカル触媒を組み上げるという戦略に基づき、C(sp3)-H結合の切断を起点とした選択的な分子変換法を開拓する。

  2. ラジカルの発生と反応制御を担う触媒の創製と分子変換法の開拓

    Grant number:23H04907  2023.4 - 2028.3

    科学研究費助成事業  学術変革領域研究(A)

    大井 貴史

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    Authorship:Principal investigator 

    Grant amount:\145990000 ( Direct Cost: \112300000 、 Indirect Cost:\33690000 )

    天然に豊富に存在する多彩な物質を炭素資源として活用するためには、有機分子に遍在するC-H結合の直接的な変換法の開拓、ならびにそれら変換反応の制御を担う触媒の創製が必須となる。本計画研究では、主として水素原子移動から進行するラジカル反応の開発に焦点を当て、C-H結合切断と続く結合形成を制御するための触媒・方法論を開拓することで、官能基を必要としない化学合成を確立する。具体的には、酸化剤を必要としないアクセプターレス脱水素型クロスカップリングや、飽和炭化水素の脱水素反応によって生成するオレフィンを標的とした選択的分子変換反応を実現する。

  3. Green Catalysis Science for Renovating Transformation of Carbon-Based Resources

    Grant number:23H04901  2023.4 - 2028.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Transformative Research Areas (A)

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    Authorship:Principal investigator 

    Grant amount:\49660000 ( Direct Cost: \38200000 、 Indirect Cost:\11460000 )

  4. 水素原子移動触媒ハイブリッド法に基づく革新的分子変換

    Grant number:23H00296  2023.4 - 2026.3

    科学研究費助成事業  基盤研究(A)

    大井 貴史

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    Authorship:Principal investigator 

    Grant amount:\47060000 ( Direct Cost: \36200000 、 Indirect Cost:\10860000 )

    結合の切断は、分子変換に欠かせない最も基本的な素過程である。炭素-ハロゲン(C-X)結合等の切断が容易な結合を利用する手法は分子変換を容易にするものの、適用できる基質が限定されるといったデメリットを生む。一方、有機分子に遍在するC-H結合の切断を起点とすれば、究極的にはあらゆる有機化合物を基質とする分子変換が可能になる。本研究では、2つの異なるC(sp3)-H結合の切断を伴うC-H/C-Hクロスカップリングを実現するための方法論を確立し、多様な化合物の自在変換に資する有機合成化学の開拓を目指す。

  5. Dynamic Element-Effect Design for Unconventional Molecular Functions

    Grant number:22K21346  2022.12 - 2029.3

    Grants-in-Aid for Scientific Research  Fund for the Promotion of Joint International Research (International Leading Research )

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    Authorship:Coinvestigator(s) 

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Industrial property rights 11

  1. 軸不斉を有する光学活性な4級アンモニウム塩を相間移動触媒として用いるβ-ヒドロキシアミノ酸誘導体の製造方法

    丸岡 啓二,大井 貴史

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    Applicant:長瀬産業株式会社

    Date applied:2002

    Announcement no:特開2003-327566 

    Patent/Registration no:特-4217085  Date registered:2009.1 

    Country of applicant:Domestic  

  2. Chiral tetraaminophosphonium salts, catalyst for asymmetric synthesis and method for producing chiral beta-nitroalcohol

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    Date applied:2009

    Announcement no:US-A1-2009131716-2009-05-21 

    Country of applicant:Foreign country  

  3. Preparation of optically active tetraaminophosphonium salts, catalysts for the asymmetric synthesis reactions, asymmetric synthesis reaction, and asymmetric-synthesis method of tetrasubstituted .alpha.- amino-acid containing peptide.

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    Date applied:2008.9

    Announcement no:JP-A-2010059133 

    Country of applicant:Domestic  

  4. Catalyst capable of allowing Strecker reaction to proceed stereoselectively and method for stereoselectively producing .alpha.-aminonitrile derivative using the same.

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    Date applied:2006

    Announcement no:WO-A1-2007074553 

    Country of applicant:Foreign country  

  5. 光学活性なビシナルジアミンおよびその製造方法

    丸岡 啓二,大井 貴史

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    Applicant:長瀬産業株式会社

    Date applied:2004

    Announcement no:特開2005-232103 

    Date registered:2005 

    Country of applicant:Domestic  

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Teaching Experience (On-campus) 195

  1. 卒業研究A

    2020

  2. 卒業研究B

    2020

  3. 化学生命工学序論

    2020

  4. 化学生命工学演習

    2020

  5. Organic Chemistry 4 with Exercises

    2020

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Academic Activities 1

  1. Associate Editor for ACS Catalysis International contribution

    Role(s):Review, evaluation, Peer review

    American Chemical Society  2015.4

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    Type:Peer review